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Co-administration of PEGylated Apohemoglobin and Haptoglobin can Limit Vascular Dysfunction in the Microcirculation and Prevent Acute Inflammation. J Appl Physiol (1985). 2024 Aug 15.
Munoz CJ, Lucas D, Muller CR, Martinez J, O'Boyle Q, Pires IS, Palmer AF, Cabrales P. PMID: 39143905.
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Degree of PEGylatation of Lumbricus terrestris Hemoglobin Improves Microcirculatory Blood Flow but Increases the Rate of Auto-Oxidation. ACS Appl Bio Mater. 2024 Jul 05.
Munoz CJ, Lucas D, Muller CR, Breton A, Jani V, Savla C, Palmer AF, Cabrales P. PMID: 38970152.
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AnimalsCells
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Toxic side-effects of diaspirin cross-linked human hemoglobin are attenuated by the apohemoglobin-haptoglobin complex. Biomed Pharmacother. 2024 May; 174:116569.
Munoz CJ, Lucas D, Martinez J, Ricario M, O'Boyle QT, Pires IS, Palmer AF, Cabrales P. PMID: 38603886.
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HumansAnimals
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A mathematical model of tissue axial and radial diffusion in the microvasculature for intravascular microscopy and phosphorescence quenching data. Comput Biol Med. 2024 May; 174:108406.
Jani VP, Jani VP, Munoz C, Cabrales P. PMID: 38603898.
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AnimalsCells
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Focal drug-resistant temporal lobe epilepsy associated with an ipsilateral anterior choroidal artery aneurysm: illustrative case. J Neurosurg Case Lessons. 2023 Jun 26; 5(26).
Phillips HW, Rangwala SD, Papadakis J, Segar DJ, Tsuboyama M, Pinto ALR, Harmon JP, Soriano SG, Munoz CJ, Madsen JR, See AP, Stone SS. PMID: 37399139; PMCID: PMC10550554.
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Airway Impedance: A Novel Diagnostic Tool to Predict Extraesophageal Airway Inflammation. J Pediatr. 2023 05; 256:5-10.e2.
Rosen R, Rahbar R, Watters K, Hseu A, Munoz CJ, Ferrari L, Holzman R, Mohammad S, Cohen A, Du M, Akkara A, Catacora A, Simoneau T, Connearney S, Mitchell P, Nurko S. PMID: 36403673.
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Humans
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Apohemoglobin-haptoglobin complex alleviates iron toxicity in mice with β-thalassemia via scavenging of cell-free hemoglobin and heme. Biomed Pharmacother. 2022 Dec; 156:113911.
Munoz CJ, Pires IS, Jani V, Gopal S, Palmer AF, Cabrales P. PMID: 36308920.
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1 Fields:
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Animals
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Hyperspectral wide-field-of-view imaging to study dynamic microcirculatory changes during hypoxia. Am J Physiol Heart Circ Physiol. 2022 07 01; 323(1):H49-H58.
Lucas A, Munoz C, Cabrales P. PMID: 35522555; PMCID: PMC9169845.
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1 Fields:
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Animals
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Implications of microvascular dysfunction and nitric oxide mediated inflammation in severe COVID-19 infection. Am J Med Sci. 2022 09; 364(3):251-256.
Jani VP, Munoz CJ, Govender K, Williams AT, Cabrales P. PMID: 35469768; PMCID: PMC9027037.
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PubMed Mentions:
1 Fields:
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HumansPHPublic Health
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Attenuating ischemia-reperfusion injury with polymerized albumin. J Appl Physiol (1985). 2022 02 01; 132(2):489-496.
Belcher DA, Williams AT, Munoz CJ, Muller CR, Walser C, Palmer AF, Cabrales P. PMID: 34913740; PMCID: PMC8816619.
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1 Fields:
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HumansAnimalsCells
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Purification and analysis of a protein cocktail capable of scavenging cell-free hemoglobin, heme, and iron. Transfusion. 2021 06; 61(6):1894-1907.
Pires IS, Govender K, Munoz CJ, Williams AT, O'Boyle QT, Savla C, Cabrales P, Palmer AF. PMID: 33817808.
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2 Fields:
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HumansAnimals
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Application of negative tissue interstitial pressure improves functional capillary density after hemorrhagic shock in the absence of volume resuscitation. Physiol Rep. 2021 03; 9(5):e14783.
Jani VP, Jani VP, Munoz CJ, Govender K, Williams AT, Cabrales P. PMID: 33661575; PMCID: PMC7931804.
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1 Fields:
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Animals
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Negative pressure increases microvascular perfusion during severe hemorrhagic shock. Microvasc Res. 2021 03; 134:104125.
Govender K, Munoz CJ, Williams AT, Cabrales P. PMID: 33346023; PMCID: PMC7856175.
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2 Fields:
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Animals
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Resuscitation After Hemorrhagic Shock in the Microcirculation: Targeting Optimal Oxygen Delivery in the Design of Artificial Blood Substitutes. Front Med (Lausanne). 2020; 7:585638.
Munoz C, Aletti F, Govender K, Cabrales P, Kistler EB. PMID: 33195342; PMCID: PMC7652927.
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4
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Safety profile of high molecular weight polymerized hemoglobins. Transfusion. 2021 01; 61(1):212-224.
Muller CR, Williams AT, Munoz CJ, Eaker AM, Breton AN, Palmer AF, Cabrales P. PMID: 33104250.
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5 Fields:
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HumansAnimalsCells
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Polymerized human hemoglobin increases the effectiveness of cisplatin-based chemotherapy in non-small cell lung cancer. Oncotarget. 2020 Oct 20; 11(42):3770-3781.
Lucas A, Belcher DA, Munoz C, Williams AT, Palmer AF, Cabrales P. PMID: 33144918; PMCID: PMC7584239.
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4 Fields:
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Resuscitation From Hemorrhagic Shock With Fresh and Stored Blood and Polymerized Hemoglobin. Shock. 2020 10; 54(4):464-473.
Williams AT, Lucas A, Muller CR, Munoz C, Bolden-Rush C, Palmer AF, Cabrales P. PMID: 32097242; PMCID: PMC7442586.
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PubMed Mentions:
8 Fields:
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Animals
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Purification of Lumbricus terrestris Mega-Hemoglobin for Diverse Oxygen Therapeutic Applications. ACS Biomater Sci Eng. 2020 09 14; 6(9):4957-4968.
Savla C, Munoz C, Hickey R, Belicak M, Gilbert C, Cabrales P, Palmer AF. PMID: 33313397; PMCID: PMC7725263.
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3 Fields:
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HumansAnimalsCells
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Enhanced Photodynamic Therapy Using the Apohemoglobin-Haptoglobin Complex as a Carrier of Aluminum Phthalocyanine. ACS Appl Bio Mater. 2020 Jul 20; 3(7):4495-4506.
Pires IS, O'Boyle QT, Munoz CJ, Savla C, Cabrales P, Palmer AF. PMID: 35025448.
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2 Fields:
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Apohemoglobin-haptoglobin complexes attenuate the hypertensive response to low-molecular-weight polymerized hemoglobin. Blood Adv. 2020 06 23; 4(12):2739-2750.
Belcher DA, Munoz C, Pires IS, Williams AT, Cabrales P, Palmer AF. PMID: 32559292; PMCID: PMC7322967.
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Animals
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Apohemoglobin-haptoglobin complex attenuates the pathobiology of circulating acellular hemoglobin and heme. Am J Physiol Heart Circ Physiol. 2020 05 01; 318(5):H1296-H1307.
Munoz CJ, Pires IS, Baek JH, Buehler PW, Palmer AF, Cabrales P. PMID: 32302494; PMCID: PMC7346542.
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PubMed Mentions:
5 Fields:
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HumansAnimalsCells
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A Review on Microvascular Hemodynamics: The Control of Blood Flow Distribution and Tissue Oxygenation. Crit Care Clin. 2020 Apr; 36(2):293-305.
Munoz CJ, Lucas A, Williams AT, Cabrales P. PMID: 32172814; PMCID: PMC7093304.
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PubMed Mentions:
10 Fields:
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HumansCells
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Numerical Model for the Determination of Erythrocyte Mechanical Properties and Wall Shear Stress in vivo From Intravital Microscopy. Front Physiol. 2019; 10:1562.
Jani VP, Lucas A, Jani VP, Munoz C, Williams AT, Ortiz D, Yalcin O, Cabrales P. PMID: 32038273; PMCID: PMC6989587.
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3