Tom Alsaigh

Title(s)Assistant Professor Of Clinical, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Patients with Prior Exposure to a Combination of Statins & Angiotensin-Converting Enzyme Inhibitors (ACE-Is)/Angiotensin Receptor Blockers (ARBs) Have Better Outcomes after Carotid Revascularization than Patients with Prior Exposure to Statins Alone: A MultiCenter Analysis. Ann Vasc Surg. 2024 Mar; 100:165-171. Willie-Permor D, Rahgozar S, Zarrintan S, Alsaigh T, Gaffey AC, Malas MB. PMID: 37852362.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    2. An Alternate Explanation. Reply. N Engl J Med. 2023 Sep 28; 389(13):1251. Alsaigh T, Leeper NJ, Sayed N. PMID: 37754300.
      View in: PubMed   Mentions:    Fields:    
    3. Combined near infrared photoacoustic imaging and ultrasound detects vulnerable atherosclerotic plaque. Biomaterials. 2023 11; 302:122314. Schneider MK, Wang J, Kare A, Adkar SS, Salmi D, Bell CF, Alsaigh T, Wagh D, Coller J, Mayer A, Snyder SJ, Borowsky AD, Long SR, Lansberg MG, Steinberg GK, Heit JJ, Leeper NJ, Ferrara KW. PMID: 37776766; PMCID: PMC10872807.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Combined near infrared photoacoustic imaging and ultrasound detects vulnerable atherosclerotic plaque. medRxiv. 2023 Jun 12. Schneider MK, Wang J, Kare A, Adkar SS, Salmi D, Bell CF, Alsaigh T, Wagh D, Coller J, Mayer A, Snyder SJ, Borowsky AD, Long SR, Lansberg MG, Steinberg GK, Heit JJ, Leeper NJ, Ferrara KW. PMID: 37398016; PMCID: PMC10312879.
      View in: PubMed   Mentions:
    5. An Alternate Explanation. N Engl J Med. 2023 Apr 06; 388(14):1318-1324. Alsaigh T, Dhaliwal G, Fukaya E, Leeper NJ, Sayed N. PMID: 37018496; PMCID: PMC10409491.
      View in: PubMed   Mentions:    Fields:    
    6. Dynamic changes in chromatin accessibility are associated with the atherogenic transitioning of vascular smooth muscle cells. Cardiovasc Res. 2022 10 21; 118(13):2792-2804. Wang Y, Gao H, Wang F, Ye Z, Mokry M, Turner AW, Ye J, Koplev S, Luo L, Alsaigh T, Adkar SS, Elishaev M, Gao X, Maegdefessel L, Björkegren JLM, Pasterkamp G, Miller CL, Ross EG, Leeper NJ. PMID: 34849613; PMCID: PMC9586565.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    7. Decoding the transcriptome of calcified atherosclerotic plaque at single-cell resolution. Commun Biol. 2022 Oct 12; 5(1):1084. Alsaigh T, Evans D, Frankel D, Torkamani A. PMID: 36224302; PMCID: PMC9556750.
      View in: PubMed   Mentions: 31  Translation:HumansCells
    8. Varicose Veins and Chronic Venous Disease. Cardiol Clin. 2021 Nov; 39(4):567-581. Alsaigh T, Fukaya E. PMID: 34686268.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Bench-to-Bedside in Vascular Medicine: Optimizing the Translational Pipeline for Patients With Peripheral Artery Disease. Circ Res. 2021 06 11; 128(12):1927-1943. Alsaigh T, Di Bartolo BA, Mulangala J, Figtree GA, Leeper NJ. PMID: 34110900; PMCID: PMC8208504.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    10. What Should Clinicians Do to Engage the Public About Gene Editing? AMA J Ethics. 2019 12 01; 21(12):E1089-1097. Alsaigh T, Nicholson L, Topol E. PMID: 31876474.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Cleavage of the leptin receptor by matrix metalloproteinase-2 promotes leptin resistance and obesity in mice. Sci Transl Med. 2018 08 22; 10(455). Mazor R, Friedmann-Morvinski D, Alsaigh T, Kleifeld O, Kistler EB, Rousso-Noori L, Huang C, Li JB, Verma IM, Schmid-Schönbein GW. PMID: 30135249; PMCID: PMC9678493.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    12. In vivo analysis of intestinal permeability following hemorrhagic shock. World J Crit Care Med. 2015 Nov 04; 4(4):287-95. Alsaigh T, Chang M, Richter M, Mazor R, Kistler EB. PMID: 26557479; PMCID: PMC4631874.
      View in: PubMed   Mentions: 8  
    13. Cellular and molecular basis of Venous insufficiency. Vasc Cell. 2014; 6(1):24. Pocock ES, Alsaigh T, Mazor R, Schmid-Schönbein GW. PMID: 25520775; PMCID: PMC4268799.
      View in: PubMed   Mentions: 21  
    14. Matrix metalloproteinase-1-mediated up-regulation of vascular endothelial growth factor-2 in endothelial cells. J Biol Chem. 2013 Jan 04; 288(1):598-607. Mazor R, Alsaigh T, Shaked H, Altshuler AE, Pocock ES, Kistler EB, Karin M, Schmid-Schönbein GW. PMID: 23155052; PMCID: PMC3537058.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    15. Impaired small-bowel barrier integrity in the presence of lumenal pancreatic digestive enzymes leads to circulatory shock. Shock. 2012 Aug; 38(3):262-7. Kistler EB, Alsaigh T, Chang M, Schmid-Schönbein GW. PMID: 22576000; PMCID: PMC3422435.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    16. Breakdown of mucin as barrier to digestive enzymes in the ischemic rat small intestine. PLoS One. 2012; 7(6):e40087. Chang M, Alsaigh T, Kistler EB, Schmid-Schönbein GW. PMID: 22768227; PMCID: PMC3387149.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    17. Acute venous occlusion enhances matrix metalloprotease activity: Implications on endothelial dysfunction. Microvasc Res. 2011 Jan; 81(1):108-16. Alsaigh T, Pocock ES, Bergan JJ, Schmid-Schönbein GW. PMID: 20923679; PMCID: PMC3021174.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    18. Mechanisms in experimental venous valve failure and their modification by Daflon 500 mg. Eur J Vasc Endovasc Surg. 2008 Jan; 35(1):102-10. Pascarella L, Lulic D, Penn AH, Alsaigh T, Lee J, Shin H, Kapur V, Bergan JJ, Schmid-Schönbein GW. PMID: 17890112.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
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