Christopher Putnam

Title(s)Associate Adjunct Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research Activities and Funding
    FEN1 Endonuclease as a Synthetic Lethal Target for Cancer Therapy
    NIH R01CA255341Aug 15, 2021 - Jul 31, 2026
    Role: Co-Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Identification of different classes of genome instability suppressor genes through analysis of DNA damage response markers. G3 (Bethesda). 2024 Mar 25. Li BZ, Kolodner RD, Putnam CD. PMID: 38526099.
      View in: PubMed   Mentions:    Fields:    
    2. Loss of mitochondrial DNA is associated with reduced DNA content variability in Saccharomyces cerevisiae. MicroPubl Biol. 2024; 2024. Putnam CD. PMID: 38533353; PMCID: PMC10964099.
      View in: PubMed   Mentions:
    3. The discovery of NLRP3 and its function in cryopyrin-associated periodic syndromes and innate immunity. Immunol Rev. 2023 Dec 25. Putnam CD, Broderick L, Hoffman HM. PMID: 38146057.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. Insights into DNA cleavage by MutL homologs from analysis of conserved motifs in eukaryotic Mlh1. Bioessays. 2023 09; 45(9):e2300031. Putnam CD, Kolodner RD. PMID: 37424007; PMCID: PMC10530380.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome. N Engl J Med. 2023 Jun 15; 388(24):2241-2252. Baghdassarian H, Blackstone SA, Clay OS, Philips R, Matthiasardottir B, Nehrebecky M, Hua VK, McVicar R, Liu Y, Tucker SM, Randazzo D, Deuitch N, Rosenzweig S, Mark A, Sasik R, Fisch KM, Pimpale Chavan P, Eren E, Watts NR, Ma CA, Gadina M, Schwartz DM, Sanyal A, Werner G, Murdock DR, Horita N, Chowdhury S, Dimmock D, Jepsen K, Remmers EF, Goldbach-Mansky R, Gahl WA, O'Shea JJ, Milner JD, Lewis NE, Chang J, Kastner DL, Torok K, Oda H, Putnam CD, Broderick L. PMID: 37256972; PMCID: PMC10392571.
      View in: PubMed   Mentions: 7     Fields:    
    6. The unstructured linker of Mlh1 contains a motif required for endonuclease function which is mutated in cancers. Proc Natl Acad Sci U S A. 2022 10 18; 119(42):e2212870119. Torres KA, Calil FA, Zhou AL, DuPrie ML, Putnam CD, Kolodner RD. PMID: 36215471; PMCID: PMC9586283.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    7. Mlh1 interacts with both Msh2 and Msh6 for recruitment during mismatch repair. DNA Repair (Amst). 2022 11; 119:103405. DuPrie ML, Palacio T, Calil FA, Kolodner RD, Putnam CD. PMID: 36122480; PMCID: PMC9639671.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Rad5 and Its Human Homologs, HLTF and SHPRH, Are Novel Interactors of Mismatch Repair. Front Cell Dev Biol. 2022; 10:843121. Miller AK, Mao G, Knicely BG, Daniels HG, Rahal C, Putnam CD, Kolodner RD, Goellner EM. PMID: 35784486; PMCID: PMC9243396.
      View in: PubMed   Mentions:
    9. Disease-associated mutations in topoisomerase IIβ result in defective NK cells. J Allergy Clin Immunol. 2022 06; 149(6):2171-2176.e3. Broderick L, Clay GM, Blum RH, Liu Y, McVicar R, Papes F, Booshehri LM, Cowell IG, Austin CA, Putnam CD, Kaufman DS. PMID: 35063500.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    10. Rad27 and Exo1 function in different excision pathways for mismatch repair in Saccharomyces cerevisiae. Nat Commun. 2021 09 22; 12(1):5568. Calil FA, Li BZ, Torres KA, Nguyen K, Bowen N, Putnam CD, Kolodner RD. PMID: 34552065; PMCID: PMC8458276.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    11. Strand discrimination in DNA mismatch repair. DNA Repair (Amst). 2021 09; 105:103161. Putnam CD. PMID: 34171627; PMCID: PMC8785607.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    12. Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function. Blood. 2021 05 06; 137(18):2450-2462. Aluri J, Bach A, Kaviany S, Chiquetto Paracatu L, Kitcharoensakkul M, Walkiewicz MA, Putnam CD, Shinawi M, Saucier N, Rizzi EM, Harmon MT, Keppel MP, Ritter M, Similuk M, Kulm E, Joyce M, de Jesus AA, Goldbach-Mansky R, Lee YS, Cella M, Kendall PL, Dinauer MC, Bednarski JJ, Bemrich-Stolz C, Canna SW, Abraham SM, Demczko MM, Powell J, Jones SM, Scurlock AM, De Ravin SS, Bleesing JJ, Connelly JA, Rao VK, Schuettpelz LG, Cooper MA. PMID: 33512449; PMCID: PMC8109013.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    13. A Case of Severe Combined Immunodeficiency Missed by Newborn Screening. J Clin Immunol. 2021 08; 41(6):1352-1355. Kitcharoensakkul M, Aluri J, Elsharkawi I, Steed A, Putnam CD, Swayampakula AK, Cooper MA, Bednarski JJ. PMID: 33712943; PMCID: PMC7954206.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    14. Ligation of newly replicated DNA controls the timing of DNA mismatch repair. Curr Biol. 2021 03 22; 31(6):1268-1276.e6. Reyes GX, Kolodziejczak A, Devakumar LJPS, Kubota T, Kolodner RD, Putnam CD, Hombauer H. PMID: 33417883; PMCID: PMC8281387.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    15. Mechanisms underlying genome instability mediated by formation of foldback inversions in Saccharomyces cerevisiae. Elife. 2020 08 07; 9. Li BZ, Putnam CD, Kolodner RD. PMID: 32762846; PMCID: PMC7467729.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    16. MutS sliding clamps on an uncertain track to DNA mismatch repair. Proc Natl Acad Sci U S A. 2020 08 25; 117(34):20351-20353. Putnam CD. PMID: 32753381; PMCID: PMC7456105.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    17. FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination. Proc Natl Acad Sci U S A. 2020 08 11; 117(32):19415-19424. Guo E, Ishii Y, Mueller J, Srivatsan A, Gahman T, Putnam CD, Wang JYJ, Kolodner RD. PMID: 32719125; PMCID: PMC7431096.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    18. Author Correction: Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners. Nat Struct Mol Biol. 2019 Dec; 26(12):1184. Goellner EM, Putnam CD, Graham WJ, Rahal CM, Li BZ, Kolodner RD. PMID: 31686054.
      View in: PubMed   Mentions:    Fields:    
    19. Mutations in topoisomerase IIβ result in a B cell immunodeficiency. Nat Commun. 2019 08 13; 10(1):3644. Broderick L, Yost S, Li D, McGeough MD, Booshehri LM, Guaderrama M, Brydges SD, Kucharova K, Patel NC, Harr M, Hakonarson H, Zackai E, Cowell IG, Austin CA, Hügle B, Gebauer C, Zhang J, Xu X, Wang J, Croker BA, Frazer KA, Putnam CD, Hoffman HM. PMID: 31409799; PMCID: PMC6692411.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    20. Essential Saccharomyces cerevisiae genome instability suppressing genes identify potential human tumor suppressors. Proc Natl Acad Sci U S A. 2019 08 27; 116(35):17377-17382. Srivatsan A, Li B, Sanchez DN, Somach SB, da Silva VL, de Souza SJ, Putnam CD, Kolodner RD. PMID: 31409704; PMCID: PMC6717276.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    21. Alternative splicing regulates stochastic NLRP3 activity. Nat Commun. 2019 07 19; 10(1):3238. Hoss F, Mueller JL, Rojas Ringeling F, Rodriguez-Alcazar JF, Brinkschulte R, Seifert G, Stahl R, Broderick L, Putnam CD, Kolodner RD, Canzar S, Geyer M, Hoffman HM, Latz E. PMID: 31324763; PMCID: PMC6642158.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    22. Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microb Cell. 2019 Jan 07; 6(1):1-64. Klein HL, Bacinskaja G, Che J, Cheblal A, Elango R, Epshtein A, Fitzgerald DM, Gómez-González B, Khan SR, Kumar S, Leland BA, Marie L, Mei Q, Miné-Hattab J, Piotrowska A, Polleys EJ, Putnam CD, Radchenko EA, Saada AA, Sakofsky CJ, Shim EY, Stracy M, Xia J, Yan Z, Yin Y, Aguilera A, Argueso JL, Freudenreich CH, Gasser SM, Gordenin DA, Haber JE, Ira G, Jinks-Robertson S, King MC, Kolodner RD, Kuzminov A, Lambert SA, Lee SE, Miller KM, Mirkin SM, Petes TD, Rosenberg SM, Rothstein R, Symington LS, Zawadzki P, Kim N, Lisby M, Malkova A. PMID: 30652105; PMCID: PMC6334234.
      View in: PubMed   Mentions: 25  
    23. EPCAM mutation update: Variants associated with congenital tufting enteropathy and Lynch syndrome. Hum Mutat. 2019 02; 40(2):142-161. Pathak SJ, Mueller JL, Okamoto K, Das B, Hertecant J, Greenhalgh L, Cole T, Pinsk V, Yerushalmi B, Gurkan OE, Yourshaw M, Hernandez E, Oesterreicher S, Naik S, Sanderson IR, Axelsson I, Agardh D, Boland CR, Martin MG, Putnam CD, Sivagnanam M. PMID: 30461124; PMCID: PMC6328345.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    24. The properties of Msh2-Msh6 ATP binding mutants suggest a signal amplification mechanism in DNA mismatch repair. J Biol Chem. 2018 11 23; 293(47):18055-18070. Graham WJ, Putnam CD, Kolodner RD. PMID: 30237169; PMCID: PMC6254361.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    25. The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects. Nat Commun. 2018 09 11; 9(1):3680. Srivatsan A, Li BZ, Szakal B, Branzei D, Putnam CD, Kolodner RD. PMID: 30206225; PMCID: PMC6134005.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    26. Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners. Nat Struct Mol Biol. 2018 08; 25(8):650-659. Goellner EM, Putnam CD, Graham WJ, Rahal CM, Li BZ, Kolodner RD. PMID: 30061603; PMCID: PMC6837739.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    27. SUMO E3 ligase Mms21 prevents spontaneous DNA damage induced genome rearrangements. PLoS Genet. 2018 03; 14(3):e1007250. Liang J, Li BZ, Tan AP, Kolodner RD, Putnam CD, Zhou H. PMID: 29505562; PMCID: PMC5860785.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    28. Cdc73 suppresses genome instability by mediating telomere homeostasis. PLoS Genet. 2018 01; 14(1):e1007170. Nene RV, Putnam CD, Li BZ, Nguyen KG, Srivatsan A, Campbell CS, Desai A, Kolodner RD. PMID: 29320491; PMCID: PMC5779705.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    29. Analyzing Genome Rearrangements in Saccharomyces cerevisiae. Methods Mol Biol. 2018; 1672:43-61. Srivatsan A, Putnam CD, Kolodner RD. PMID: 29043616; PMCID: PMC5657460.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    30. Pathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiae. Genetics. 2017 07; 206(3):1187-1225. Putnam CD, Kolodner RD. PMID: 28684602; PMCID: PMC5500125.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    31. Correction: Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements. PLoS Genet. 2016 Aug; 12(8):e1006302. Albuquerque CP, Wang G, Lee NS, Kolodner RD, Putnam CD, Zhou H. PMID: 27579875; PMCID: PMC5006978.
      View in: PubMed   Mentions:    Fields:    
    32. Guinier peak analysis for visual and automated inspection of small-angle X-ray scattering data. J Appl Crystallogr. 2016 Oct 01; 49(Pt 5):1412-1419. Putnam CD. PMID: 27738411; PMCID: PMC5045725.
      View in: PubMed   Mentions: 20  
    33. A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers. Nat Commun. 2016 Apr 13; 7:11256. Putnam CD, Srivatsan A, Nene RV, Martinez SL, Clotfelter SP, Bell SN, Somach SB, de Souza JE, Fonseca AF, de Souza SJ, Kolodner RD. PMID: 27071721; PMCID: PMC4833866.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    34. Evolution of the methyl directed mismatch repair system in Escherichia coli. DNA Repair (Amst). 2016 Feb; 38:32-41. Putnam CD. PMID: 26698649; PMCID: PMC4740232.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    35. Exonuclease 1-dependent and independent mismatch repair. DNA Repair (Amst). 2015 Aug; 32:24-32. Goellner EM, Putnam CD, Kolodner RD. PMID: 25956862; PMCID: PMC4522362.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    36. PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair. Mol Cell. 2014 Jul 17; 55(2):291-304. Goellner EM, Smith CE, Campbell CS, Hombauer H, Desai A, Putnam CD, Kolodner RD. PMID: 24981171; PMCID: PMC4113420.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    37. Mlh2 is an accessory factor for DNA mismatch repair in Saccharomyces cerevisiae. PLoS Genet. 2014 May; 10(5):e1004327. Campbell CS, Hombauer H, Srivatsan A, Bowen N, Gries K, Desai A, Putnam CD, Kolodner RD. PMID: 24811092; PMCID: PMC4014439.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    38. DNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures. PLoS Genet. 2014 Apr; 10(4):e1004277. Putnam CD, Pallis K, Hayes TK, Kolodner RD. PMID: 24699249; PMCID: PMC3974649.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    39. A saccharomyces cerevisiae RNase H2 interaction network functions to suppress genome instability. Mol Cell Biol. 2014 Apr; 34(8):1521-34. Allen-Soltero S, Martinez SL, Putnam CD, Kolodner RD. PMID: 24550002; PMCID: PMC3993591.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    40. Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway. PLoS Genet. 2013 Oct; 9(10):e1003869. Smith CE, Mendillo ML, Bowen N, Hombauer H, Campbell CS, Desai A, Putnam CD, Kolodner RD. PMID: 24204293; PMCID: PMC3814310.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    41. DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals. Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43):17308-13. Hura GL, Tsai CL, Claridge SA, Mendillo ML, Smith JM, Williams GJ, Mastroianni AJ, Alivisatos AP, Putnam CD, Kolodner RD, Tainer JA. PMID: 24101514; PMCID: PMC3808630.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    42. Distinct SUMO ligases cooperate with Esc2 and Slx5 to suppress duplication-mediated genome rearrangements. PLoS Genet. 2013; 9(8):e1003670. Albuquerque CP, Wang G, Lee NS, Kolodner RD, Putnam CD, Zhou H. PMID: 23935535; PMCID: PMC3731205.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    43. Bioinformatic identification of genes suppressing genome instability. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):E3251-9. Putnam CD, Allen-Soltero SR, Martinez SL, Chan JE, Hayes TK, Kolodner RD. PMID: 23129647; PMCID: PMC3511103.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    44. Engineered disulfide-forming amino acid substitutions interfere with a conformational change in the mismatch recognition complex Msh2-Msh6 required for mismatch repair. J Biol Chem. 2012 Nov 30; 287(49):41232-44. Hargreaves VV, Putnam CD, Kolodner RD. PMID: 23045530; PMCID: PMC3510822.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    45. Mutations of complement factor I and potential mechanisms of neuroinflammation in acute hemorrhagic leukoencephalitis. J Clin Immunol. 2013 Jan; 33(1):162-71. Broderick L, Gandhi C, Mueller JL, Putnam CD, Shayan K, Giclas PC, Peterson KS, Aceves SS, Sheets RM, Peterson BM, Newbury RO, Hoffman HM, Bastian JF. PMID: 22926405; PMCID: PMC3540165.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    46. Mismatch repair, but not heteroduplex rejection, is temporally coupled to DNA replication. Science. 2011 Dec 23; 334(6063):1713-6. Hombauer H, Srivatsan A, Putnam CD, Kolodner RD. PMID: 22194578; PMCID: PMC3806717.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    47. A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):18748-53. Zimmermann C, Chymkowitch P, Eldholm V, Putnam CD, Lindvall JM, Omerzu M, Bjørås M, Kolodner RD, Enserink JM. PMID: 22042866; PMCID: PMC3219101.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    48. Cancer. Aneuploidy drives a mutator phenotype in cancer. Science. 2011 Aug 19; 333(6045):942-3. Kolodner RD, Cleveland DW, Putnam CD. PMID: 21852477; PMCID: PMC3806716.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    49. Determination of gross chromosomal rearrangement rates. Cold Spring Harb Protoc. 2010 Sep 01; 2010(9):pdb.prot5492. Putnam CD, Kolodner RD. PMID: 20810639; PMCID: PMC3047512.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    50. Post-replication repair suppresses duplication-mediated genome instability. PLoS Genet. 2010 May 06; 6(5):e1000933. Putnam CD, Hayes TK, Kolodner RD. PMID: 20463880; PMCID: PMC2865514.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    51. Functional studies and homology modeling of Msh2-Msh3 predict that mispair recognition involves DNA bending and strand separation. Mol Cell Biol. 2010 Jul; 30(13):3321-8. Dowen JM, Putnam CD, Kolodner RD. PMID: 20421420; PMCID: PMC2897569.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    52. Probing DNA- and ATP-mediated conformational changes in the MutS family of mispair recognition proteins using deuterium exchange mass spectrometry. J Biol Chem. 2010 Apr 23; 285(17):13170-82. Mendillo ML, Putnam CD, Mo AO, Jamison JW, Li S, Woods VL, Kolodner RD. PMID: 20181951; PMCID: PMC2857143.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    53. A conserved MutS homolog connector domain interface interacts with MutL homologs. Proc Natl Acad Sci U S A. 2009 Dec 29; 106(52):22223-8. Mendillo ML, Hargreaves VV, Jamison JW, Mo AO, Li S, Putnam CD, Woods VL, Kolodner RD. PMID: 20080788; PMCID: PMC2796910.
      View in: PubMed   Mentions: 49     Fields:    Translation:Cells
    54. Specific pathways prevent duplication-mediated genome rearrangements. Nature. 2009 Aug 20; 460(7258):984-9. Putnam CD, Hayes TK, Kolodner RD. PMID: 19641493; PMCID: PMC2785216.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    55. Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity. Immunity. 2009 Jun 19; 30(6):875-87. Brydges SD, Mueller JL, McGeough MD, Pena CA, Misaghi A, Gandhi C, Putnam CD, Boyle DL, Firestein GS, Horner AA, Soroosh P, Watford WT, O'Shea JJ, Kastner DL, Hoffman HM. PMID: 19501000; PMCID: PMC2759865.
      View in: PubMed   Mentions: 177     Fields:    Translation:AnimalsCells
    56. Perspectives on the DNA damage and replication checkpoint responses in Saccharomyces cerevisiae. DNA Repair (Amst). 2009 Sep 02; 8(9):974-82. Putnam CD, Jaehnig EJ, Kolodner RD. PMID: 19477695; PMCID: PMC2725198.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    57. X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution. Q Rev Biophys. 2007 Aug; 40(3):191-285. Putnam CD, Hammel M, Hura GL, Tainer JA. PMID: 18078545.
      View in: PubMed   Mentions: 507     Fields:    Translation:Cells
    58. Coupling distant sites in DNA during DNA mismatch repair. Proc Natl Acad Sci U S A. 2007 Aug 07; 104(32):12953-4. Kolodner RD, Mendillo ML, Putnam CD. PMID: 17664420; PMCID: PMC1941800.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    59. Chimeric Saccharomyces cerevisiae Msh6 protein with an Msh3 mispair-binding domain combines properties of both proteins. Proc Natl Acad Sci U S A. 2007 Jun 26; 104(26):10956-61. Shell SS, Putnam CD, Kolodner RD. PMID: 17573527; PMCID: PMC1904149.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    60. The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA. Mol Cell. 2007 May 25; 26(4):565-78. Shell SS, Putnam CD, Kolodner RD. PMID: 17531814; PMCID: PMC2001284.
      View in: PubMed   Mentions: 72     Fields:    Translation:Animals
    61. Escherichia coli MutS tetramerization domain structure reveals that stable dimers but not tetramers are essential for DNA mismatch repair in vivo. J Biol Chem. 2007 Jun 01; 282(22):16345-54. Mendillo ML, Putnam CD, Kolodner RD. PMID: 17426027.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    62. The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model. Arthritis Rheum. 2007 Apr; 56(4):1273-1285. Aksentijevich I, Putnam CD, Remmers EF, Mueller JL, Le J, Kolodner RD, Moak Z, Chuang M, Austin F, Goldbach-Mansky R, Hoffman HM, Kastner DL. PMID: 17393462; PMCID: PMC4321998.
      View in: PubMed   Mentions: 145     Fields:    Translation:HumansCells
    63. Chromosome healing by de novo telomere addition in Saccharomyces cerevisiae. Mol Microbiol. 2006 Mar; 59(5):1357-68. Pennaneach V, Putnam CD, Kolodner RD. PMID: 16468981.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    64. Analysis of gross-chromosomal rearrangements in Saccharomyces cerevisiae. Methods Enzymol. 2006; 409:462-76. Schmidt KH, Pennaneach V, Putnam CD, Kolodner RD. PMID: 16793418.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    65. Protein mimicry of DNA and pathway regulation. DNA Repair (Amst). 2005 Dec 08; 4(12):1410-20. Putnam CD, Tainer JA. PMID: 16226493.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    66. Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype. Mol Cell Biol. 2005 Aug; 25(16):7226-38. Putnam CD, Pennaneach V, Kolodner RD. PMID: 16055731; PMCID: PMC1190249.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    67. Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice. Nat Genet. 2005 Jul; 37(7):750-5. Wang Y, Putnam CD, Kane MF, Zhang W, Edelmann L, Russell R, Carrión DV, Chin L, Kucherlapati R, Kolodner RD, Edelmann W. PMID: 15965476.
      View in: PubMed   Mentions: 83     Fields:    Translation:AnimalsCells
    68. Chromosome healing through terminal deletions generated by de novo telomere additions in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13262-7. Putnam CD, Pennaneach V, Kolodner RD. PMID: 15328403; PMCID: PMC516557.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    69. Mechanism and energetics of green fluorescent protein chromophore synthesis revealed by trapped intermediate structures. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12111-6. Barondeau DP, Putnam CD, Kassmann CJ, Tainer JA, Getzoff ED. PMID: 14523232; PMCID: PMC218721.
      View in: PubMed   Mentions: 62     Fields:    Translation:Cells
    70. Maintenance of genome stability in Saccharomyces cerevisiae. Science. 2002 Jul 26; 297(5581):552-7. Kolodner RD, Putnam CD, Myung K. PMID: 12142524.
      View in: PubMed   Mentions: 247     Fields:    Translation:AnimalsCells
    71. Structure and function correlation in histone H2A peptide-mediated gene transfer. Proc Natl Acad Sci U S A. 2002 May 28; 99(11):7467-71. Balicki D, Putnam CD, Scaria PV, Beutler E. PMID: 12032306; PMCID: PMC124254.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    72. DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes. Prog Nucleic Acid Res Mol Biol. 2001; 68:315-47. Hosfield DJ, Daniels DS, Mol CD, Putnam CD, Parikh SS, Tainer JA. PMID: 11554309.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    73. Lessons learned from structural results on uracil-DNA glycosylase. Mutat Res. 2000 Aug 30; 460(3-4):183-99. Parikh SS, Putnam CD, Tainer JA. PMID: 10946228.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    74. Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism. J Mol Biol. 2000 Feb 11; 296(1):295-309. Putnam CD, Arvai AS, Bourne Y, Tainer JA. PMID: 10656833.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    75. The food of sweet and bitter fancy. Nat Struct Biol. 2000 Jan; 7(1):17-8. Putnam CD, Tainer JA. PMID: 10625418.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    76. Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex. Nat Struct Biol. 1999 Oct; 6(10):932-6. Han S, Craig JA, Putnam CD, Carozzi NB, Tainer JA. PMID: 10504727.
      View in: PubMed   Mentions: 78     Fields:    Translation:Cells
    77. Mutation of an active site residue in Escherichia coli uracil-DNA glycosylase: effect on DNA binding, uracil inhibition and catalysis. Biochemistry. 1999 Apr 13; 38(15):4834-45. Shroyer MJ, Bennett SE, Putnam CD, Tainer JA, Mosbaugh DW. PMID: 10200172.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    78. Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase. J Mol Biol. 1999 Mar 26; 287(2):331-46. Putnam CD, Shroyer MJ, Lundquist AJ, Mol CD, Arvai AS, Mosbaugh DW, Tainer JA. PMID: 10080896.
      View in: PubMed   Mentions: 55     Fields:    Translation:Cells
    79. DNA repair mechanisms for the recognition and removal of damaged DNA bases. Annu Rev Biophys Biomol Struct. 1999; 28:101-28. Mol CD, Parikh SS, Putnam CD, Lo TP, Tainer JA. PMID: 10410797.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    80. Rational design of a functional metalloenzyme: introduction of a site for manganese binding and oxidation into a heme peroxidase. Biochemistry. 1998 Dec 01; 37(48):16853-62. Wilcox SK, Putnam CD, Sastry M, Blankenship J, Chazin WJ, McRee DE, Goodin DB. PMID: 9836578.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    81. The RNA polymerase I transactivator upstream binding factor requires its dimerization domain and high-mobility-group (HMG) box 1 to bend, wrap, and positively supercoil enhancer DNA. Mol Cell Biol. 1994 Oct; 14(10):6476-88. Putnam CD, Copenhaver GP, Denton ML, Pikaard CS. PMID: 7935371; PMCID: PMC359177.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    82. The RNA polymerase I transcription factor UBF is a sequence-tolerant HMG-box protein that can recognize structured nucleic acids. Nucleic Acids Res. 1994 Jul 11; 22(13):2651-7. Copenhaver GP, Putnam CD, Denton ML, Pikaard CS. PMID: 8041627; PMCID: PMC308223.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    83. Cooperative binding of the Xenopus RNA polymerase I transcription factor xUBF to repetitive ribosomal gene enhancers. Mol Cell Biol. 1992 Nov; 12(11):4970-80. Putnam CD, Pikaard CS. PMID: 1406673; PMCID: PMC360429.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
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