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    Barbara Parker

    TitleProfessor Of Clinical
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9500 Gilman Drive #0987
    CA La Jolla 92093
    Phone858-822-6135
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      Research Interests
      My research interests include personalized approaches to cancer screening and prevention, new therapies on genomic profiling and breast cancer survivorship issues. I served as the Medical Director of the WHEL Diet Study. I currently serve as the CALGB/Alliance/ACTION clinical trials UCSD Principal Investigator and serve on the CALGB/Alliance Breast Committee and the CALGB/Alliance Prevention Committee. I serve as site PI and Co-Chair of the Diagnosis and Treatment Clinical Care and Research Group of the California Athena Breast Health Network, co-investigator of studies of life-style modification in breast cancer survivors, and co-investigator of studies involving new agents. My clinical practice is comprised of breast cancer patients.

      Education and Training
      BA - Chemistry - University of North Carolina at Chapel Hill, NC - 1974
      MD - Medicine - Stanford University of Medicine, CA - 1981
      Intern/Resident - Medicine - UC San Diego Department of Medicine, CA - 1982-1984
      Chief Resident - Medicine - UC San Diego Department of Medicine, CA - 1985
      Fellowship - Hematology/Oncology - UC San Diego Department of Medicine, CA - 1987


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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Bao L, Messer K, Schwab R, Harismendy O, Pu M, Crain B, Yost S, Frazer KA, Rana B, Hasteh F, Wallace A, Parker BA. Mutational Profiling Can Establish Clonal or Independent Origin in Synchronous Bilateral Breast and Other Tumors. PLoS One. 2015; 10(11):e0142487. PMID: 26554380.
        View in: PubMed
      2. Patel SP, Schwaederle M, Daniels GA, Fanta PT, Schwab RB, Shimabukuro KA, Kesari S, Piccioni DE, Bazhenova LA, Helsten TL, Lippman SM, Parker BA, Kurzrock R. Molecular inimitability amongst tumors: implications for precision cancer medicine in the age of personalized oncology. Oncotarget. 2015 Oct 20; 6(32):32602-9. PMID: 26418953.
        View in: PubMed
      3. Hartman SJ, Natarajan L, Palmer BW, Parker B, Patterson RE, Sears DD. Impact of increasing physical activity on cognitive functioning in breast cancer survivors: Rationale and study design of Memory & Motion. Contemp Clin Trials. 2015 Nov; 45(Pt B):371-6. PMID: 26427563.
        View in: PubMed
      4. Rock CL, Flatt SW, Byers TE, Colditz GA, Demark-Wahnefried W, Ganz PA, Wolin KY, Elias A, Krontiras H, Liu J, Naughton M, Pakiz B, Parker BA, Sedjo RL, Wyatt H. Results of the Exercise and Nutrition to Enhance Recovery and Good Health for You (ENERGY) Trial: A Behavioral Weight Loss Intervention in Overweight or Obese Breast Cancer Survivors. J Clin Oncol. 2015 Oct 1; 33(28):3169-76. PMID: 26282657.
        View in: PubMed
      5. Schwab RB, Kato S, Crain B, Pu M, Messer K, Weidner N, Blair SL, Wallace AM, Carson DA, Parker BA. A window-of-opportunity biomarker study of etodolac in resectable breast cancer. Cancer Med. 2015 Oct; 4(10):1583-8. PMID: 26275572.
        View in: PubMed
      6. Parker BA, Schwaederlé M, Scur MD, Boles SG, Helsten T, Subramanian R, Schwab RB, Kurzrock R. Breast Cancer Experience of the Molecular Tumor Board at the University of California, San Diego Moores Cancer Center. J Oncol Pract. 2015 Nov; 11(6):442-9. PMID: 26243651.
        View in: PubMed
      7. Schwaederle M, Daniels GA, Piccioni DE, Kesari S, Fanta PT, Schwab RB, Shimabukuro KA, Parker BA, Kurzrock R. Next generation sequencing demonstrates association between tumor suppressor gene aberrations and poor outcome in patients with cancer. Cell Cycle. 2015 Jun 3; 14(11):1730-7. PMID: 25928476.
        View in: PubMed
      8. Kato S, Schwaederle M, Daniels GA, Piccioni D, Kesari S, Bazhenova L, Shimabukuro K, Parker BA, Fanta P, Kurzrock R. Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics. Cell Cycle. 2015 Apr 18; 14(8):1252-9. PMID: 25695927.
        View in: PubMed
      9. Schwaederle M, Daniels GA, Piccioni DE, Fanta PT, Schwab RB, Shimabukuro KA, Parker BA, Kurzrock R. On the Road to Precision Cancer Medicine: Analysis of Genomic Biomarker Actionability in 439 Patients. Mol Cancer Ther. 2015 Jun; 14(6):1488-94. PMID: 25852059.
        View in: PubMed
      10. Schwaederlé M, Daniels GA, Piccioni DE, Fanta PT, Schwab RB, Shimabukuro KA, Parker BA, Kurzrock R. Cyclin alterations in diverse cancers: Outcome and co-amplification network. Oncotarget. 2015 Feb 20; 6(5):3033-42. PMID: 25596748.
        View in: PubMed
      11. Scott BJ, van Vugt VA, Rush T, Brown T, Chen CC, Carter BS, Schwab R, Fanta P, Helsten T, Bazhenova L, Parker B, Pingle S, Saria MG, Brown BD, Piccioni DE, Kesari S. Concurrent intrathecal methotrexate and liposomal cytarabine for leptomeningeal metastasis from solid tumors: a retrospective cohort study. J Neurooncol. 2014 Sep; 119(2):361-8. PMID: 24942463.
        View in: PubMed
      12. Wheler JJ, Parker BA, Lee JJ, Atkins JT, Janku F, Tsimberidou AM, Zinner R, Subbiah V, Fu S, Schwab R, Moulder S, Valero V, Schwaederle M, Yelensky R, Miller VA, Stephens MP, Meric-Bernstam F, Kurzrock R. Unique molecular signatures as a hallmark of patients with metastatic breast cancer: Implications for current treatment paradigms. Oncotarget. 2014 May 15; 5(9):2349-54. PMID: 24811890.
        View in: PubMed
      13. Schwaederle M, Parker BA, Schwab RB, Fanta PT, Boles SG, Daniels GA, Bazhenova LA, Subramanian R, Coutinho AC, Ojeda-Fournier H, Datnow B, Webster NJ, Lippman SM, Kurzrock R. Molecular tumor board: the university of california san diego moores cancer center experience. Oncologist. 2014 Jun; 19(6):631-6. PMID: 24797821.
        View in: PubMed
      14. Ancoli-Israel S, Liu L, Rissling M, Natarajan L, Neikrug AB, Palmer BW, Mills PJ, Parker BA, Sadler GR, Maglione J. Sleep, fatigue, depression, and circadian activity rhythms in women with breast cancer before and after treatment: a 1-year longitudinal study. Support Care Cancer. 2014 Sep; 22(9):2535-45. PMID: 24733634.
        View in: PubMed
      15. Yan M, Parker BA, Schwab R, Kurzrock R. HER2 aberrations in cancer: implications for therapy. Cancer Treat Rev. 2014 Jul; 40(6):770-80. PMID: 24656976.
        View in: PubMed
      16. Harismendy O, Schwab RB, Alakus H, Yost SE, Matsui H, Hasteh F, Wallace AM, Park HL, Madlensky L, Parker B, Carpenter PM, Jepsen K, Anton-Culver H, Frazer KA. Evaluation of ultra-deep targeted sequencing for personalized breast cancer care. Breast Cancer Res. 2013; 15(6):R115. PMID: 24326041.
        View in: PubMed
      17. Rock CL, Pande C, Flatt SW, Ying C, Pakiz B, Parker BA, Williams K, Bardwell WA, Heath DD, Nichols JF. Favorable changes in serum estrogens and other biologic factors after weight loss in breast cancer survivors who are overweight or obese. Clin Breast Cancer. 2013 Jun; 13(3):188-95. PMID: 23375717.
        View in: PubMed
      18. Rock CL, Byers TE, Colditz GA, Demark-Wahnefried W, Ganz PA, Wolin KY, Elias A, Krontiras H, Liu J, Naughton M, Pakiz B, Parker BA, Sedjo RL, Wyatt H. Reducing breast cancer recurrence with weight loss, a vanguard trial: the Exercise and Nutrition to Enhance Recovery and Good Health for You (ENERGY) Trial. Contemp Clin Trials. 2013 Mar; 34(2):282-95. PMID: 23266440.
        View in: PubMed
      19. Cadmus-Bertram L, Wang JB, Patterson RE, Newman VA, Parker BA, Pierce JP. Web-based self-monitoring for weight loss among overweight/obese women at increased risk for breast cancer: the HELP pilot study. Psychooncology. 2013 Aug; 22(8):1821-8. PMID: 23188655.
        View in: PubMed
      20. Jeste N, Liu L, Rissling M, Trofimenko V, Natarajan L, Parker BA, Ancoli-Israel S. Prevention of quality-of-life deterioration with light therapy is associated with changes in fatigue in women with breast cancer undergoing chemotherapy. Qual Life Res. 2013 Aug; 22(6):1239-44. PMID: 22865153.
        View in: PubMed
      21. Saquib J, Parker BA, Natarajan L, Madlensky L, Saquib N, Patterson RE, Newman VA, Pierce JP. Prognosis following the use of complementary and alternative medicine in women diagnosed with breast cancer. Complement Ther Med. 2012 Oct; 20(5):283-90. PMID: 22863642.
        View in: PubMed
      22. Yost SE, Smith EN, Schwab RB, Bao L, Jung H, Wang X, Voest E, Pierce JP, Messer K, Parker BA, Harismendy O, Frazer KA. Identification of high-confidence somatic mutations in whole genome sequence of formalin-fixed breast cancer specimens. Nucleic Acids Res. 2012 Aug; 40(14):e107. PMID: 22492626.
        View in: PubMed
      23. Liu L, Mills PJ, Rissling M, Fiorentino L, Natarajan L, Dimsdale JE, Sadler GR, Parker BA, Ancoli-Israel S. Fatigue and sleep quality are associated with changes in inflammatory markers in breast cancer patients undergoing chemotherapy. Brain Behav Immun. 2012 Jul; 26(5):706-13. PMID: 22406004.
        View in: PubMed
      24. Liu L, Rissling M, Natarajan L, Fiorentino L, Mills PJ, Dimsdale JE, Sadler GR, Parker BA, Ancoli-Israel S. The longitudinal relationship between fatigue and sleep in breast cancer patients undergoing chemotherapy. Sleep. 2012 Feb; 35(2):237-45. PMID: 22294814.
        View in: PubMed
      25. Neikrug AB, Rissling M, Trofimenko V, Liu L, Natarajan L, Lawton S, Parker BA, Ancoli-Israel S. Bright light therapy protects women from circadian rhythm desynchronization during chemotherapy for breast cancer. Behav Sleep Med. 2012; 10(3):202-16. PMID: 22742438.
        View in: PubMed
      26. Ancoli-Israel S, Rissling M, Neikrug A, Trofimenko V, Natarajan L, Parker BA, Lawton S, Desan P, Liu L. Light treatment prevents fatigue in women undergoing chemotherapy for breast cancer. Support Care Cancer. 2012 Jun; 20(6):1211-9. PMID: 21660669.
        View in: PubMed
      27. Al-Delaimy WK, Flatt SW, Natarajan L, Laughlin GA, Rock CL, Gold EB, Caan BJ, Parker BA, Pierce JP. IGF1 and risk of additional breast cancer in the WHEL study. Endocr Relat Cancer. 2011 Apr; 18(2):235-44. PMID: 21263044.
        View in: PubMed
      28. Saquib N, Pierce JP, Saquib J, Flatt SW, Natarajan L, Bardwell WA, Patterson RE, Stefanick ML, Thomson CA, Rock CL, Jones LA, Gold EB, Karanja N, Parker BA. Poor physical health predicts time to additional breast cancer events and mortality in breast cancer survivors. Psychooncology. 2011 Mar; 20(3):252-9. PMID: 20878837.
        View in: PubMed
      29. Patterson RE, Flatt SW, Newman VA, Natarajan L, Rock CL, Thomson CA, Caan BJ, Parker BA, Pierce JP. Marine fatty acid intake is associated with breast cancer prognosis. J Nutr. 2011 Feb; 141(2):201-6. PMID: 21178081.
        View in: PubMed
      30. Erickson K, Patterson RE, Flatt SW, Natarajan L, Parker BA, Heath DD, Laughlin GA, Saquib N, Rock CL, Pierce JP. Clinically defined type 2 diabetes mellitus and prognosis in early-stage breast cancer. J Clin Oncol. 2011 Jan 1; 29(1):54-60. PMID: 21115861.
        View in: PubMed
      31. Patterson RE, Saquib N, Natarajan L, Rock CL, Parker BA, Thomson CA, Pierce JP. Improvement in self-reported physical health predicts longer survival among women with a history of breast cancer. Breast Cancer Res Treat. 2011 Jun; 127(2):541-7. PMID: 21042931.
        View in: PubMed
      32. Gorman JR, Roesch SC, Parker BA, Madlensky L, Saquib N, Newman VA, Pierce JP. Physical and mental health correlates of pregnancy following breast cancer. Psychooncology. 2010 May; 19(5):517-24. PMID: 20425779.
        View in: PubMed
      33. Patterson RE, Flatt SW, Saquib N, Rock CL, Caan BJ, Parker BA, Laughlin GA, Erickson K, Thomson CA, Bardwell WA, Hajek RA, Pierce JP. Medical comorbidities predict mortality in women with a history of early stage breast cancer. Breast Cancer Res Treat. 2010 Aug; 122(3):859-65. PMID: 20077000.
        View in: PubMed
      34. Natarajan L, Pu M, Parker BA, Thomson CA, Caan BJ, Flatt SW, Madlensky L, Hajek RA, Al-Delaimy WK, Saquib N, Gold EB, Pierce JP. Time-varying effects of prognostic factors associated with disease-free survival in breast cancer. Am J Epidemiol. 2009 Jun 15; 169(12):1463-70. PMID: 19403844.
        View in: PubMed
      35. Pierce JP, Natarajan L, Caan BJ, Flatt SW, Kealey S, Gold EB, Hajek RA, Newman VA, Rock CL, Pu M, Saquib N, Stefanick ML, Thomson CA, Parker B. Dietary change and reduced breast cancer events among women without hot flashes after treatment of early-stage breast cancer: subgroup analysis of the Women's Healthy Eating and Living Study. Am J Clin Nutr. 2009 May; 89(5):1565S-1571S. PMID: 19339393.
        View in: PubMed
      36. Liu L, Fiorentino L, Natarajan L, Parker BA, Mills PJ, Sadler GR, Dimsdale JE, Rissling M, He F, Ancoli-Israel S. Pre-treatment symptom cluster in breast cancer patients is associated with worse sleep, fatigue and depression during chemotherapy. Psychooncology. 2009 Feb; 18(2):187-94. PMID: 18677716.
        View in: PubMed
      37. Pierce JP, Newman VA, Natarajan L, Flatt SW, Al-Delaimy WK, Caan BJ, Emond JA, Faerber S, Gold EB, Hajek RA, Hollenbach K, Jones LA, Karanja N, Kealey S, Madlensky L, Marshall J, Ritenbaugh C, Rock CL, Stefanick ML, Thomson C, Wasserman L, Parker BA. Telephone counseling helps maintain long-term adherence to a high-vegetable dietary pattern. J Nutr. 2007 Oct; 137(10):2291-6. PMID: 17885013.
        View in: PubMed
      38. Pierce JP, Natarajan L, Caan BJ, Parker BA, Greenberg ER, Flatt SW, Rock CL, Kealey S, Al-Delaimy WK, Bardwell WA, Carlson RW, Emond JA, Faerber S, Gold EB, Hajek RA, Hollenbach K, Jones LA, Karanja N, Madlensky L, Marshall J, Newman VA, Ritenbaugh C, Thomson CA, Wasserman L, Stefanick ML. Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women's Healthy Eating and Living (WHEL) randomized trial. JAMA. 2007 Jul 18; 298(3):289-98. PMID: 17635889.
        View in: PubMed
      39. Pierce JP, Stefanick ML, Flatt SW, Natarajan L, Sternfeld B, Madlensky L, Al-Delaimy WK, Thomson CA, Kealey S, Hajek R, Parker BA, Newman VA, Caan B, Rock CL. Greater survival after breast cancer in physically active women with high vegetable-fruit intake regardless of obesity. J Clin Oncol. 2007 Jun 10; 25(17):2345-51. PMID: 17557947.
        View in: PubMed
      40. Mortimer JE, Flatt SW, Parker BA, Gold EB, Wasserman L, Natarajan L, Pierce JP. Tamoxifen, hot flashes and recurrence in breast cancer. Breast Cancer Res Treat. 2008 Apr; 108(3):421-6. PMID: 17541741.
        View in: PubMed
      41. Ancoli-Israel S, Liu L, Marler MR, Parker BA, Jones V, Sadler GR, Dimsdale J, Cohen-Zion M, Fiorentino L. Fatigue, sleep, and circadian rhythms prior to chemotherapy for breast cancer. Support Care Cancer. 2006 Mar; 14(3):201-9. PMID: 16010529.
        View in: PubMed
      42. Liu L, Marler MR, Parker BA, Jones V, Johnson S, Cohen-Zion M, Fiorentino L, Sadler GR, Ancoli-Israel S. The relationship between fatigue and light exposure during chemotherapy. Support Care Cancer. 2005 Dec; 13(12):1010-7. PMID: 15864659.
        View in: PubMed
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