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John Alksne

Photo of John Alksne
Title(s)Emeritus Professor, Neurological Surgery
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Overview 
    Collapse overview
    Dr. John F. Alksne, a distinguished neurosurgeon and highly respected researcher in neurological disease, joined the UC San Diego Neurosurgery faculty in 1971 as a Professor of Neurological Surgery. Dr. Alksne served as Chief of Neurological Surgery at UC San Diego until 1995. He was appointed dean of the UC San Diego School of Medicine in 1992 and appointed Vice Chancellor for Health Sciences in 1994.

    Dr. Alksne's clinical practice focuses on the care of patients suffering from trigeminal neuralgia (tic doloreux), facial tic, glossopharyngeal neuralgia, spasmodic torticollis, epilepsy, and acoustic neuroma.

    Throughout his career, Dr. Alksne has pioneered new surgical techniques and technologies to advance the treatment of diseases and disorders of the central nervous system. He established and directs the Epilepsy Surgery Program at UC San Diego, and in 1992 was honored with a Special Commendation by the Epilepsy society of San Diego County. As Dean, he has been instrumental in establishing the UC San Diego Program in Gene Therapy, which includes research, training and clinical trials in the promising new field of gene therapy.

    Dr. Alksne earned his medical degree at the University of Washington in Seattle, where he also completed his training. He was Chief of Neurosurgery at Harbor General Hospital at UCLA from 1964-67, and Professor and Chair of Neurological Surgery at the Medical College of Virginia from 1967-71.

    He is a member of numerous scientific and professional societies, including the American Association of Neurological Surgeons, the Latin American Federal of Neurosurgeons, the World Society of Stereotactic and Functional Neurosurgery, the Association of American Medical Colleges, and the Association of Academic Health Centers.

    Diseases/Research Topics
    Glioma, Malignant Glioma

    Research Interests
    Intra-tumoral infusion for malignant glioma, conducted in both clinical trials and in animal experimentation.

    Collapse Research 
    Collapse research activities and funding
    BRAIN PROTECTION DURING HYPOTHERMIC CIRCULATORY ARREST
    NIH R01NS028450Aug 1, 1992 - Jul 31, 1996
    Role: Principal Investigator
    NEUROSURGERY RESEARCH TRAINING GRANT
    NIH T32NS007342Jul 1, 1991 - Jun 30, 1997
    Role: Principal Investigator
    PREVENTION OF INTRACRANIAL ARTERIAL REACTION TO SAH
    NIH R01NS018522Sep 1, 1982 - Nov 30, 1988
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000827Mar 1, 1974 - Nov 30, 2010
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Diabetes knowledge, risk and severity perceptions, lifestyle behaviours and management barriers among Sub-Saharan African immigrants living in the UK: an ethnographic study. BMC Public Health. 2025 Aug 22; 25(1):2883. Onuorah L, Santy-Tomlinson J, Draper P. PMID: 40846934; PMCID: PMC12372270.
      View in: PubMed   Mentions:    Fields:    
    2. Graduate Students' Perspectives on Obtaining a Master's of Science in Respiratory Care. Respir Care. 2025 04; 70(4):384-392. Koster MS, McHenry KL, Caldwell-Chadwick BG, Null MM. PMID: 40193534.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Comparative risk of QTc prolongation induced by second-generation antipsychotics in the real world: retrospective cohort study based on a hospital information system. BJPsych Open. 2025 Mar 10; 11(2):e42. He L, Yu W, Song H, Li L, Shen Y, Zhang L, Li H. PMID: 40059385; PMCID: PMC12001931.
      View in: PubMed   Mentions:
    4. Association of Lower Rostral Anterior Cingulate GABA+ and Dysregulated Cortisol Stress Response With Altered Functional Connectivity in Young Adults With Lifetime Depression: A Multimodal Imaging Investigation of Trait and State Effects. Am J Psychiatry. 2024 Jul 01; 181(7):639-650. Ironside M, Duda JM, Moser AD, Holsen LM, Zuo CS, Du F, Perlo S, Richards CE, Chen X, Chen X, Nickerson LD, Null KE, Esfand SM, Alexander MM, Crowley DJ, Lauze M, Misra M, Goldstein JM, Pizzagalli DA. PMID: 38685857; PMCID: PMC11216878.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    5. [Determination of trace anions in battery-grade lithium carbonate by double-inhibition on-line matrix-removal ion chromatography]. Se Pu. 2024 Mar 08; 42(3):291-295. Wu G, Wu G, Wu GQ. PMID: 38503706; PMCID: PMC10951807.
      View in: PubMed   Mentions:    Fields:    
    6. Porcine reproductive and respiratory syndrome virus degrades DDX10 via SQSTM1/p62-dependent selective autophagy to antagonize its antiviral activity. Autophagy. 2023 08; 19(8):2257-2274. Li J, Li J, Zhou Y, Zhao W, Zhao W, Liu J, Liu J, Ullah R, Fang P, Fang L, Xiao S. PMID: 36779599; PMCID: PMC10351467.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    7. [Determination of organophosphate diesters in facility vegetable soils using ultra-high performance liquid chromatography-electrostatic field orbitrap high resolution mass spectrometry]. Se Pu. 2023 Jan; 41(1):58-65. Liu M, Wang M, Zhao A, Zhao A, Zhu L, Wang C, Wei C, Liu W, Liu W, Xu J. PMID: 36633077; PMCID: PMC9837671.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    8. [Simultaneous determination of 28 fragrance components in cosmetics by gas chromatography-tandem mass spectrometry]. Se Pu. 2023 Jan; 41(1):76-86. Xu D, Wu Y, Wu Y, Wang Y, Chen F, Chen F, Zhang S, Lai G. PMID: 36633079; PMCID: PMC9841437.
      View in: PubMed   Mentions: 1     Fields:    
    9. DBI/ACBP is a targetable autophagy checkpoint involved in aging and cardiovascular disease. Autophagy. 2023 07; 19(7):2166-2169. Montégut L, Joseph A, Chen H, Chen H, Abdellatif M, Ruckenstuhl C, Martins I, Madeo F, Kroemer G. PMID: 36579946; PMCID: PMC10283417.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    10. Author Correction: Polycomb CBX7 has a unifying role in cellular lifespan. Nat Cell Biol. 2022 Sep; 24(9):1445. Gil J, Bernard D, Martínez D, Beach D. PMID: 35941232.
      View in: PubMed   Mentions: 1     Fields:    
    11. [Plasma metabolomics in a deep vein thrombosis rat model based on ultra-high performance liquid chromatography-electrostatic field orbitrap high resolution mass spectrometry]. Se Pu. 2022 Aug; 40(8):736-745. Gu Y, Zang P, Li J, Li J, Yan Y, Wang J. PMID: 35903841; PMCID: PMC9404070.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    12. Autophagy and its mediated mitochondrial quality control maintain pollen tube growth and male fertility in Arabidopsis. Autophagy. 2023 03; 19(3):768-783. Yan H, Zhuang M, Xu X, Li S, Li S, Yang M, Li N, Du X, Hu K, Peng X, Huang W, Wu H, Wu H, Tse YC, Zhao L, Wang H. PMID: 35786359; PMCID: PMC9980518.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    13. Results of three or more Gamma Knife radiosurgery procedures for recurrent trigeminal neuralgia. J Neurosurg. 2021 12 01; 135(6):1789-1798. Gupta M, Sagi V, Mittal A, Yekula A, Hawkins D, Shimizu J, Duddleston PJ, Thomas K, Goetsch SJ, Alksne JF, Hodgens DW, Ott K, Shimizu KT, Duma C, Ben-Haim S. PMID: 34852325.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    14. Uniform criteria for total hip replacement surgery in patients with hip osteoarthritis: a decision tool to guide treatment decisions. Int J Qual Health Care. 2021 Mar 04; 33(1). Atsma F, Molenkamp O, Bouma H, Bolder SB, Groenewoud AS, Westert GP. PMID: 33616656; PMCID: PMC7941208.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Injury, Illness, and Mental Health Risks in United States Domestic Mariners. J Occup Environ Med. 2020 10; 62(10):839-841. Lefkowitz RY, Null DB, Slade MD, Redlich CA. PMID: 32769797.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Imaging examination, diagnosis, and control and prevention of nosocomial infection for coronavirus disease 2019: Expert consensus of Hunan radiologist. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2020 Mar 28; 45(3):221-228. Liu J, Liu J, Liu J, Wang W. PMID: 32386011.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    17. Tentorial sling for microvascular decompression in patients with trigeminal neuralgia: a description of operative technique and clinical outcomes. J Neurosurg. 2019 04 01; 130(4):1315-1320. Steinberg JA, Sack J, Wilson B, Weingarten D, Carter B, Khalessi A, Ben-Haim S, Alksne J. PMID: 29676696.
      View in: PubMed   Mentions: 8     Fields:    
    18. Improving the Prognostic Value of Disease-Specific Graded Prognostic Assessment Model for Renal Cell Carcinoma by Incorporation of Cumulative Intracranial Tumor Volume. World Neurosurg. 2017 Dec; 108:151-156. Ali MA, Hirshman BR, Wilson B, Schupper AJ, Joshi R, Proudfoot JA, Goetsch SJ, Alksne JF, Ott K, Aiyama H, Nagano O, Carter BS, Chiang V, Serizawa T, Yamamoto M, Chen CC. PMID: 28754641; PMCID: PMC5705321.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    19. Survival Patterns of 5750 Stereotactic Radiosurgery-Treated Patients with Brain Metastasis as a Function of the Number of Lesions. World Neurosurg. 2017 Nov; 107:944-951.e1. Ali MA, Hirshman BR, Wilson B, Carroll KT, Proudfoot JA, Goetsch SJ, Alksne JF, Ott K, Aiyama H, Nagano O, Carter BS, Fogarty G, Hong A, Serizawa T, Yamamoto M, Chen CC. PMID: 28735121; PMCID: PMC5654648.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    20. Management patterns of patients with cerebral metastases who underwent multiple stereotactic radiosurgeries. J Neurooncol. 2016 05; 128(1):119-128. Marshall DC, Marcus LP, Kim TE, McCutcheon BA, Goetsch SJ, Koiso T, Alksne JF, Ott K, Carter BS, Hattangadi-Gluth JA, Yamamoto M, Chen CC. PMID: 26948673.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    21. Stereotactic Radiosurgery Treatment of Trigeminal Neuralgia: Clinical Outcomes and Prognostic Factors. World Neurosurg. 2016 Jun; 90:604-612.e11. Taich ZJ, Goetsch SJ, Monaco E, Carter BS, Ott K, Alksne JF, Chen CC. PMID: 26915701.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    22. Prognostic factors for stereotactic radiosurgery-treated patients with cerebral metastasis: implications on randomised control trial design and inter-institutional collaboration. Eur J Cancer. 2014 Apr; 50(6):1148-58. Gonda DD, Kim TE, Goetsch SJ, Kawabe T, Watanabe S, Alksne JF, Hattangadi JA, Nitta M, Ott K, Hodgens DW, Carter BS, Yamamoto M, Chen CC. PMID: 24529832.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. Immediate post-operative brachytherapy prior to irradiation and temozolomide for newly diagnosed glioblastoma. J Neurooncol. 2013 Jul; 113(3):467-77. Waters JD, Rose B, Gonda DD, Scanderbeg DJ, Russell M, Alksne JF, Murphy K, Carter BS, Lawson J, Chen CC. PMID: 23673513.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    24. Frameless, real-time, surface imaging-guided radiosurgery: clinical outcomes for brain metastases. Neurosurgery. 2012 Oct; 71(4):844-51. Pan H, Cerviño LI, Pawlicki T, Jiang SB, Alksne J, Detorie N, Russell M, Carter BS, Murphy KT, Mundt AJ, Chen C, Lawson JD. PMID: 22989959.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    25. Patterns of imaging failures in glioblastoma patients treated with chemoradiation: a retrospective study. Med Oncol. 2012 Sep; 29(3):2040-5. Pan H, Alksne J, Mundt AJ, Murphy KT, Cornell M, Kesari S, Lawson JD. PMID: 22108847.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    26. Novel use of the Contura for high dose rate cranial brachytherapy. Med Dosim. 2011; 36(4):344-6. Scanderbeg DJ, Alksne JF, Lawson JD, Murphy KT. PMID: 21144735.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Single-isocenter frameless intensity-modulated stereotactic radiosurgery for simultaneous treatment of multiple brain metastases: clinical experience. Int J Radiat Oncol Biol Phys. 2010 Sep 01; 78(1):91-7. Nath SK, Lawson JD, Simpson DR, Vanderspek L, Wang JZ, Alksne JF, Ciacci J, Mundt AJ, Murphy KT. PMID: 20096509.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    28. Optically-guided frameless linac-based radiosurgery for brain metastases: clinical experience. J Neurooncol. 2010 Mar; 97(1):67-72. Nath SK, Lawson JD, Wang JZ, Simpson DR, Newman CB, Alksne JF, Mundt AJ, Murphy KT. PMID: 19701719; PMCID: PMC2814046.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    29. AAN-EFNS guidelines on trigeminal neuralgia management. Eur J Neurol. 2008 Oct; 15(10):1013-28. Cruccu G, Gronseth G, Alksne J, Argoff C, Brainin M, Burchiel K, Nurmikko T, Zakrzewska JM, American Academy of Neurology Society, European Federation of Neurological Society. PMID: 18721143.
      View in: PubMed   Mentions: 179     Fields:    Translation:Humans
    30. Practice parameter: the diagnostic evaluation and treatment of trigeminal neuralgia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the European Federation of Neurological Societies. Neurology. 2008 Oct 07; 71(15):1183-90. Gronseth G, Cruccu G, Alksne J, Argoff C, Brainin M, Burchiel K, Nurmikko T, Zakrzewska JM. PMID: 18716236.
      View in: PubMed   Mentions: 131     Fields:    Translation:Humans
    31. Cerebellopontine angle cyst compressing the vagus nerve: case report. Neurosurgery. 2007 Jun; 60(6):E1150; discussion 1150. Hayden MG, Tornabene SV, Nguyen A, Thekdi A, Alksne JF. PMID: 17538363.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    32. Idiopathic normal pressure hydrocephalus may be a "two hit" disease: benign external hydrocephalus in infancy followed by deep white matter ischemia in late adulthood. J Magn Reson Imaging. 2006 Oct; 24(4):747-55. Bradley WG, Bahl G, Alksne JF. PMID: 16958056.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    33. An open study of botulinum-A toxin treatment of trigeminal neuralgia. Neurology. 2006 May 09; 66(9):1458-9; author reply 1458-9. Zakrzewska JM, Cohen J, Brown J, Alksne J, Gemillion H, Linskey M, Sirois D, Pollock B. PMID: 16685762.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. Multimodality treatment of trigeminal neuralgia: impact of radiosurgery and high resolution magnetic resonance imaging. J Clin Neurosci. 2006 Feb; 13(2):239-44. Aryan HE, Nakaji P, Lu DC, Alksne JF. PMID: 16439132.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    35. Focal radiation therapy of brain metastases after complete surgical resection. Med Oncol. 2006; 23(3):317-24. Bahl G, White G, Alksne J, Vemuri L, Spear MA. PMID: 17018888.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    36. Neuropsychological change following gamma knife surgery in patients with left temporal lobe epilepsy: a review of three cases. Epilepsy Behav. 2004 Dec; 5(6):949-57. McDonald CR, Norman MA, Tecoma E, Alksne J, Iragui V. PMID: 15582844.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    37. Is a large hat size hazardous to your health? AJNR Am J Neuroradiol. 2004 Oct; 25(9):1454-5; author reply 1455. McComb JG, Bradley WG, Safar FG, Furtado C, Hurtado C, Ord J, Alksne JF. PMID: 15502119; PMCID: PMC7976427.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Increased intracranial volume: a clue to the etiology of idiopathic normal-pressure hydrocephalus? AJNR Am J Neuroradiol. 2004 Oct; 25(9):1479-84. Bradley WG, Safar FG, Furtado C, Hurtado C, Ord J, Alksne JF. PMID: 15502125; PMCID: PMC7976411.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    39. Role of proton magnetic resonance spectroscopy in the diagnosis of gliomatosis cerebri: a unique pattern of normal choline but elevated Myo-inositol metabolite levels. J Comput Assist Tomogr. 2004 Jan-Feb; 28(1):103-5. Mohana-Borges AV, Imbesi SG, Dietrich R, Alksne J, Amjadi DK. PMID: 14716242.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    40. Improvement of aggressive and antisocial behavior after resection of temporal lobe tumors. Pediatrics. 2003 Nov; 112(5):e430. Nakaji P, Meltzer HS, Singel SA, Alksne JF. PMID: 14595088.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    41. Thalamic hypometabolism in a patient undergoing vagal nerve stimulation seen on F-18 FDG PET imaging. Clin Nucl Med. 2003 Sep; 28(9):784-5. Petrucci M, Hoh C, Alksne JF. PMID: 12973011.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    42. Growth factor gene therapy for Alzheimer disease. Neurosurg Focus. 2002 Nov 15; 13(5):e5. Tuszynski MH, U HS, Alksne J, Bakay RA, Pay MM, Merrill D, Thal LJ. PMID: 15769074.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    43. Pain subsequent to resection of acoustic neuromas via suboccipital and translabyrinthine approaches. Am J Otol. 1996 Jul; 17(4):620-4. Ruckenstein MJ, Harris JP, Cueva RA, Prioleau G, Alksne J. PMID: 8841710.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    44. Pilocytic astrocytoma presenting as an extra-axial tumor in the cerebellopontine angle: case report. Neurosurgery. 1995 Jul; 37(1):125-8. Beutler AS, Hsiang JK, Moorhouse DF, Hansen LA, Alksne JF. PMID: 8587672.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    45. Intraoperative assessment of aneurysm clip placement by intravenous fluorescein angiography. Neurosurgery. 1994 Nov; 35(5):970-3; discussion 973. Wrobel CJ, Meltzer H, Lamond R, Alksne JF. PMID: 7838352.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    46. A comparison of the effects on neuronal Golgi morphology, assessed with electron microscopy, of cardiopulmonary bypass, low-flow bypass, and circulatory arrest during profound hypothermia. J Thorac Cardiovasc Surg. 1992 Nov; 104(5):1396-404. Scheller MS, Branson PJ, Cornacchia LG, Alksne JF. PMID: 1434722.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    47. Retromastoid cisternal Ommaya reservoir for intrathecal therapy of coccidioidomycosis meningitis. Technical note. J Neurosurg. 1992 Sep; 77(3):476-7. Wrobel CJ, Alksne JF. PMID: 1506899.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    48. Masking of epileptiform activity by propofol during seizure surgery. Anesthesiology. 1992 Apr; 76(4):652-4. Drummond JC, Iragui-Madoz VJ, Alksne JF, Kalkman CJ. PMID: 1550293.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    49. Effect of uridine 5'-diphosphate on cryogenic brain edema in rabbits. Stroke. 1989 Dec; 20(12):1694-9. Yoshida S, Alksne JF, Seelig JM, Bailey MD, Moore SS, Kitamura K. PMID: 2595732.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    50. Diagnosis and treatment of an odontoid fracture in a patient with polyostotic fibrous dysplasia: case report. Neurosurgery. 1989 Jun; 24(6):905-9. Stompro BE, Alksne JF, Press GA. PMID: 2747866.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    51. The transoropalatal approach to the atlantoaxial-clival region: considerations for the head and neck surgeon. Laryngoscope. 1989 May; 99(5):467-74. Harris JP, Godin MS, Krekorian TD, Alksne JF. PMID: 2709933.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    52. Experimental model of symptomatic vasospasm in rabbits. Stroke. 1988 Nov; 19(11):1420-5. Endo S, Branson PJ, Alksne JF. PMID: 3188126.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    53. Modification of experimental post-subarachnoid hemorrhage vasculopathy with intracisternal plasmin. Neurosurgery. 1988 Sep; 23(3):335-7. Alksne JF, Branson PJ, Bailey M. PMID: 2976126.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    54. Demonstration by magnetic resonance of symptomatic spinal epidural lipomatosis. Neurosurgery. 1987 Sep; 21(3):414-5. Healy ME, Hesselink JR, Ostrup RC, Alksne JF. PMID: 3670587.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    55. Intracerebral hemorrhage after experimental embolic infarction. Anticoagulation. Arch Neurol. 1987 Aug; 44(8):848-50. Lyden PD, Zivin JA, Soll M, Sitzer M, Rothrock JF, Alksne J. PMID: 3632395.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    56. Intranasal schwannoma with extension into the intracranial compartment: case report. Neurosurgery. 1986 Nov; 19(5):813-5. Zovickian J, Barba D, Alksne JF. PMID: 3785631.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    57. Modification of experimental post-subarachnoid hemorrhage vasculopathy with intracisternal plasmin. Neurosurgery. 1986 Jul; 19(1):20-5. Alksne JF, Branson PJ, Bailey M. PMID: 2944029.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    58. Intimal proliferation of cerebral arteries after subarachnoid blood injection in pigs. J Neurosurg. 1984 Sep; 61(3):494-500. Takemae T, Branson PJ, Alksne JF. PMID: 6747685.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    59. Success of microvascular decompression with and without prior surgical therapy for trigeminal neuralgia. J Neurosurg. 1984 Jan; 60(1):104-7. Barba D, Alksne JF. PMID: 6689703.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    60. Iotrol, a new myelographic agent: 2. Comparative electroencephalographic evaluation by spectrum analysis. AJNR Am J Neuroradiol. 1983 May-Jun; 4(3):319-22. Sovak M, Ranganathan R, Kerber CW, Bickford R, Alksne JF. PMID: 6410733; PMCID: PMC8334988.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    61. Prevention of arterial injury reaction to adventitial blood with intravenous persantine. Angiology. 1982 Dec; 33(12):776-80. Alksne JF, Branson PJ. PMID: 7181170.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    62. Timing of periarterial blood removal for the prevention of vasonecrosis. Angiology. 1982 Apr; 33(4):259-67. Alksne JF, Branson FJ. PMID: 7073018.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    63. Mechanisms of whole blood-induced cerebral arterial contraction. Neurosurgery. 1981 Sep; 9(3):275-82. Schumacher MA, Alksne JF. PMID: 7301070.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    64. Ferromagnetic embolization. Experimental evaluation. Radiology. 1981 Feb; 138(2):341-9. Barry JW, Bookstein JJ, Alksne JF. PMID: 7455113.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    65. Development of a multinational traumatic coma data bank. Neurosurgery. 1980 Oct; 7(4):433-4. Marshall LF, Bowers SA, Alksne JF, Sadler GR. PMID: 7442985.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    66. Microsurgical vascular decompression of cranial nerves. Am J Surg. 1980 Jul; 140(1):156-7. Alksne JF. PMID: 7396079.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    67. Stereotaxic occlusion of 22 consecutive anterior communicating artery aneurysms. J Neurosurg. 1980 Jun; 52(6):790-3. Alksne JF, Smith RW. PMID: 6991648.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    68. Changes in pituitary hormones during and following transsphenoidal removal of prolactinomas. Am J Obstet Gynecol. 1980 Feb 15; 136(4):518-23. Casper RF, Rakoff JS, Quigley ME, Gilliland B, Alksne J, Yen SS. PMID: 6766667.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    69. Pathogenesis of cerebral vasospasm. Neurol Res. 1980; 2(3-4):273-82. Alksne JF, Branson PJ. PMID: 6111035.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    70. Needle biopsy under computerized tomographic control: a method for tissue diagnosis in intracranial lesions. Neurosurgery. 1979 Dec; 5(6):671-4. James HE, Wells M, Alksne JF, Wickbom I, Siemers P, Brahme F, Rosenberg J. PMID: 534075.
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    71. Neurosurgery-epitomes of progress: hemifacial spasm or facial tic. West J Med. 1979 Nov; 131(5):429. Smith RW, Alksne J. PMID: 18748507; PMCID: PMC1271873.
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    72. Prevention of experimental subarachnoid hemorrhage-induced intracranial arterial vasonecrosis with phosphodiesterase inhibitor phthalazinol (EG-626). Stroke. 1979 Nov-Dec; 10(6):638-44. Alksne JF, Branson PJ. PMID: 118551.
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    73. Vasospasms. J Neurosurg. 1979 Oct; 51(4):576. Alksne JF. PMID: 113511.
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    74. Prevention of persistent cerebral smooth muscle contraction in response to whole blood. Stroke. 1978 Sep-Oct; 9(5):472-7. Linder M, Alksne JF. PMID: 100906.
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    75. Stereotaxic thrombosis of inaccessible intracranial aneurysms. J Neurosurg. 1977 Dec; 47(6):833-9. Smith RW, Alksne JF. PMID: 336850.
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    76. Neurosurgery-epitomes of progress: the warning leak as a clue to the presence of an intracranial aneurysm. West J Med. 1977 Sep; 127(3):232-3. Alksne JF. PMID: 18748034; PMCID: PMC1237782.
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    77. Hormonal changes following hypophysectomy in humans. Obstet Gynecol. 1977 Sep; 50(3):333-9. Lachelin GC, Yen SC, Alksne JF. PMID: 142934.
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    78. Iron-acrylic compound for steriotaxic aneurysm thrombosis. J Neurosurg. 1977 Aug; 47(2):137-41. Alksne JF, Smith RW. PMID: 327029.
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    79. Experimental models of spasm. Clin Neurosurg. 1977; 24:216-27. Alksne JF, Smith RW. PMID: 412632.
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    80. A comparison of intimal proliferation in experimental subarachnoid hemorrhage and atherosclerosis. Angiology. 1976 Dec; 27(12):712-20. Alksne JF, Branson PJ. PMID: 1078306.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    81. Infections complicating the use of external ventriculostomy. J Neurosurg. 1976 May; 44(5):567-70. Smith RW, Alksne JF. PMID: 1262916.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    82. Experimental catecholamine-induced chronic cerebral vasospasm. Myonecrosis in vessel wall. J Neurosurg. 1974 Oct; 41(4):440-5. Alksne JF, Greenhoot JH. PMID: 4213103.
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    83. Myonecrosis in chronic experimental vasospasm. Surgery. 1974 Jul; 76(1):1-7. Alksne JF. PMID: 4210214.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    84. Functional ultrastructure of the arachnoid villus. Arch Neurol. 1972 Nov; 27(5):371-7. Alksne JF, Lovings ET. PMID: 5078893.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    85. The role of the arachnoid villus in the removal of red blood cells from the subarachnoid space. An electron microscope study in the dog. J Neurosurg. 1972 Feb; 36(2):192-200. Alksne JF, Lovings ET. PMID: 5008733.
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    86. Stereotactic thrombosis of intracranial aneurysms. N Engl J Med. 1971 Jan 28; 284(4):171-4. Alksne JF. PMID: 4923683.
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    87. Arachnoid villi after subarachnoid blood. J Neuropathol Exp Neurol. 1971 Jan; 30(1):135. Alksne JF. PMID: 5542521.
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    88. Stereotactic thrombosis of intracranial aneurysms. Neurology. 1970 Apr; 20(4):376. Alksne JF. PMID: 4935021.
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    89. Brain death as seen by the neurosurgeon. Laval Med. 1970 Feb; 41(2):180-2. Alksne JF. PMID: 4929490.
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    90. En bloc resection of the pterygoid region in the management of advanced oropharyngeal carcinoma. Surg Gynecol Obstet. 1970 Feb; 130(2):349-52. Terz JJ, Alksne JF, Lawrence W. PMID: 5411284.
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    91. Management of subarachnoid hemorrhage. Va Med Mon (1918). 1970 Feb; 97(2):95-8. Alksne JF. PMID: 4950766.
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    92. Craniofacial resection for tumors invading the pterygoid fossa. Am J Surg. 1969 Nov; 118(5):732-40. Terz JJ, Alksne JF, Lawrence W. PMID: 5347091.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    93. Osteochondroma of the base of the skull causing an isolated oculomotor nerve paralysis. Case report emphasizing microsurgical techniques. J Neurosurg. 1969 Aug; 31(2):230-3. Bakdash H, Alksne JF, Rand RW. PMID: 5803809.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    94. Stereotactic thrombosis of intracranial aneurysms using a magnetic probe. Confin Neurol. 1969; 31(1):95-8. Alksne JF. PMID: 4900495.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    95. Transport of intrathecal I-125 RISA to circulating plasma. A test for communicating hydrocephalus. Neurology. 1968 Sep; 18(9):870-4. Abbott M, Alksne JF. PMID: 5303180.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    96. Magnetically controlled intravascular catheter. Surgery. 1968 Jul; 64(1):339-45. Alksne JF. PMID: 5658737.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    97. The surgical challenge of carotid-cavernous fistula: the critical role of intracranial circulatory dynamics. J Neurosurg. 1967 Oct; 27(4):298-308. Stern WE, Brown WJ, Alksne JF. PMID: 6054733.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    98. The stereotaxic obliteration of intracranial aneurysms. Bull Los Angeles Neurol Soc. 1967 Apr; 32(2):77-85. Feigenbaum J, Alksne J. PMID: 5340509.
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    99. Magnetic probe for the stereotactic thrombosis of intracranial aneurysms. J Neurol Neurosurg Psychiatry. 1967 Apr; 30(2):159-62. Alksne JF, Fingerhut AG, Rand RW. PMID: 5340536; PMCID: PMC496155.
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    100. Brain scan and twist drill needle biopsy of metastatic brain tumors. Am Surg. 1967 Jan; 33(1):31-5. Killeffer FA, Alksne JF. PMID: 6016516.
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    101. Magnetically controlled focal intravascular thrombosis in dogs. J Neurosurg. 1966 Nov; 25(5):516-25. Alksne JF, Fingerhut AG, Rand RW. PMID: 5926317.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    102. Thrombosis of intracranial aneurysms. An experimental approach utilizing magnetically controlled iron particles. Radiology. 1966 Feb; 86(2):342-3. Fingerhut AG, Alksne JF. PMID: 5902473.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    103. Electron microscopy of axon degeneration: a valuable tool in experimental neuroanatomy. Ergeb Anat Entwicklungsgesch. 1966; 39(1):3-32. Alksne JF, Blackstad TW, Walberg F, White LE. PMID: 6005628.
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    104. Magnetically controlled metallic thrombosis of intracranial aneurysms. A preliminary report. Bull Los Angeles Neurol Soc. 1965 Sep; 30(3):153-5. Alksne JF, Fingerhut AG. PMID: 5847973.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    105. Electron-microscope study of the effect of increased intracranial pressure on the arachnoid villus. J Neurosurg. 1965 May; 22(5):481-8. Alksne JF, White LE. PMID: 5825610.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    106. EXPERIMENTAL PSYCHOSOMATIC DISEASE STATES IN MONKEYS. II. GUT HYPERMOTILITY. J Surg Res. 1964 Oct; 4:454-64. FOLTZ EL, MILLET FE, WEBER DE, ALKSNE JF. PMID: 14224008.
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    107. The passage of colloidal particles across the dermal capillary wall under the influence of histamine. Q J Exp Physiol Cogn Med Sci. 1959 Jan; 44(1):51-66. ALKSNE JF. PMID: 13624013.
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