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    Miles Wilkinson

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentReproductive Medicine
    Address9500 Gilman Drive #0695
    CA La Jolla 92093
    Phone858-822-4819
    vCardDownload vCard

      Collapse Research 
      Collapse Research Activities and Funding
      Spermatogonial Stem Cell Establishment
      NIH/NIGMS R01GM119128May 1, 2016 - Apr 30, 2020
      Role: Principal Investigator
      Cisplatin-induced epigenomic modifications in male germ cells
      NIH/NICHD R01HD082065Dec 1, 2015 - Nov 30, 2017
      Role: Principal Investigator
      The Role of NMD in Olfactory Neurogenesis
      NIH/NIGMS R01GM111838Jul 10, 2014 - Apr 30, 2018
      Role: Principal Investigator
      Androgen-Dependent Rhox Homeobox Genes
      NIH/NICHD R01HD053808May 7, 2007 - Mar 31, 2013
      Role: Principal Investigator
      Conditional Knockout of WT1 in Sertoli Cells In Vivo
      NIH/NICHD R01HD042714Mar 1, 2003 - Feb 28, 2010
      Role: Principal Investigator
      Regulation of RNA Surveillance
      NIH/NIGMS R01GM058595Jan 1, 1999 - Jun 30, 2013
      Role: Principal Investigator
      Regulation and Function of the Rhox5 Homeobox Gene
      NIH/NICHD R01HD045595May 1, 1991 - May 31, 2014
      Role: Principal Investigator
      PEM HOMEOBOX GENE
      NIH/NCI R01CA078023May 1, 1991 - Jan 31, 2004
      Role: Principal Investigator
      PEM-A NOVEL GENE EXPRESSED IN EMBRYOS AND TUMOR CELLS
      NIH/NICHD R01HD027233May 1, 1991 - Dec 31, 1997
      Role: Principal Investigator
      REGULATION OF T-CELL RECEPTOR EXPRESSION
      NIH/NIGMS R01GM039586Feb 1, 1988 - Aug 31, 1999
      Role: Principal Investigator
      REGULATION OF T-CELL RECEPTOR GENE EXPRESSION
      NIH/NIGMS R29GM039586Feb 1, 1988 - Jan 31, 1993
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Goetz AE, Wilkinson M. Stress and the nonsense-mediated RNA decay pathway. Cell Mol Life Sci. 2017 May 13. PMID: 28503708.
        View in: PubMed
      2. Jones SH, Wilkinson M. RNA Decay, Evolution, and the Testis. RNA Biol. 2016 Dec 02; 0. PMID: 27911186.
        View in: PubMed
      3. Borgmann J, Tüttelmann F, Dworniczak B, Röpke A, Song HW, Kliesch S, Wilkinson M, Laurentino S, Gromoll J. The human RHOX gene cluster: target genes and functional analysis of gene variants in infertile men. Hum Mol Genet. 2016 Nov 15; 25(22):4898-4910. PMID: 28171660.
        View in: PubMed
      4. Song HW, Bettegowda A, Lake BB, Zhao AH, Skarbrevik D, Babajanian E, Sukhwani M, Shum EY, Phan MH, Plank TD, Richardson ME, Ramaiah M, Sridhar V, de Rooij DG, Orwig KE, Zhang K, Wilkinson M. The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment. Cell Rep. 2016 Sep 27; 17(1):149-64. PMID: 27681428.
        View in: PubMed
      5. Lu J, Plank TD, Su F, Shi X, Liu C, Ji Y, Li S, Huynh A, Shi C, Zhu B, Yang G, Wu Y, Wilkinson M, Lu Y. The nonsense-mediated RNA decay pathway is disrupted in inflammatory myofibroblastic tumors. J Clin Invest. 2016 Aug 1; 126(8):3058-62. PMID: 27348585.
        View in: PubMed
      6. Lou CH, Dumdie J, Goetz A, Shum EY, Brafman D, Liao X, Mora-Castilla S, Ramaiah M, Cook-Andersen H, Laurent L, Wilkinson M. Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate. Stem Cell Reports. 2016 Jun 14; 6(6):844-57. PMID: 27304915.
        View in: PubMed
      7. Shum EY, Jones SH, Shao A, Dumdie J, Krause MD, Chan WK, Lou CH, Espinoza JL, Song HW, Phan MH, Ramaiah M, Huang L, McCarrey JR, Peterson KJ, De Rooij DG, Cook-Andersen H, Wilkinson M. The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay. Cell. 2016 Apr 7; 165(2):382-95. PMID: 27040500.
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      8. Cook-Andersen H, Wilkinson M. Molecular biology: Splicing does the two-step. Nature. 2015 May 21; 521(7552):300-1. PMID: 25970243.
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      9. Shum EY, Espinoza JL, Ramaiah M, Wilkinson M. Identification of novel post-transcriptional features in olfactory receptor family mRNAs. Nucleic Acids Res. 2015 Oct 30; 43(19):9314-26. PMID: 25908788.
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      10. Lou CH, Shum EY, Wilkinson M. RNA degradation drives stem cell differentiation. EMBO J. 2015 Jun 12; 34(12):1606-8. PMID: 25899816.
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      11. Wilkinson M. Evidence that DNA methylation engenders dynamic gene regulation. Proc Natl Acad Sci U S A. 2015 Apr 28; 112(17):E2116. PMID: 25848065.
        View in: PubMed
      12. Karam R, Lou CH, Kroeger H, Huang L, Lin JH, Wilkinson M. The unfolded protein response is shaped by the NMD pathway. EMBO Rep. 2015 May; 16(5):599-609. PMID: 25807986.
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      13. Song HW, Bettegowda A, Oliver D, Yan W, Phan MH, de Rooij DG, Corbett MA, Wilkinson M. shRNA Off-Target Effects In Vivo: Impaired Endogenous siRNA Expression and Spermatogenic Defects. PLoS One. 2015; 10(3):e0118549. PMID: 25790000.
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      14. Shao A, Wilkinson M. Suppressing nonsense-a surprising function for 5-azacytidine. EMBO Mol Med. 2014; 6(12):1518-20. PMID: 25378479.
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      15. Rao MK, Matsumoto Y, Richardson ME, Panneerdoss S, Bhardwaj A, Ward JM, Shanker S, Bettegowda A, Wilkinson M. Hormone-induced and DNA Demethylation-induced Relief of a Tissue-specific and Developmentally Regulated Block in Transcriptional Elongation. J Biol Chem. 2014 Dec 19; 289(51):35087-101. PMID: 25331959.
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      16. Liu C, Karam R, Zhou Y, Su F, Ji Y, Li G, Xu G, Lu L, Wang C, Song M, Zhu J, Wang Y, Zhao Y, Foo WC, Zuo M, Valasek MA, Javle M, Wilkinson M, Lu Y. The UPF1 RNA surveillance gene is commonly mutated in pancreatic adenosquamous carcinoma. Nat Med. 2014 Jun; 20(6):596-8. PMID: 24859531.
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      17. De Gendt K, Verhoeven G, Amieux PS, Wilkinson M. Research Resource: Genome-Wide Identification of AR-Regulated Genes Translated in Sertoli Cells In Vivo Using the RiboTag Approach. Mol Endocrinol. 2014 Apr; 28(4):575-91. PMID: 24606126.
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      18. Song HW, Wilkinson M. Transcriptional control of spermatogonial maintenance and differentiation. Semin Cell Dev Biol. 2014 Jun; 30:14-26. PMID: 24560784.
        View in: PubMed
      19. Lou CH, Shao A, Shum EY, Espinoza JL, Huang L, Karam R, Wilkinson M. Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway. Cell Rep. 2014 Feb 27; 6(4):748-64. PMID: 24529710.
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      20. Nguyen LS, Wilkinson M, Gecz J. Nonsense-mediated mRNA decay: inter-individual variability and human disease. Neurosci Biobehav Rev. 2014 Oct; 46 Pt 2:175-86. PMID: 24239855.
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      21. Lasalde C, Rivera AV, León AJ, González-Feliciano JA, Estrella LA, Rodríguez-Cruz EN, Correa ME, Cajigas IJ, Bracho DP, Vega IE, Wilkinson M, González CI. Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1. Nucleic Acids Res. 2014 Feb 1; 42(3):1916-29. PMID: 24198248.
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      22. Maclean JA, Hu Z, Welborn JP, Song HW, Rao MK, Wayne CM, Wilkinson M. The RHOX Homeodomain Proteins Regulate the Expression of Insulin and Other Metabolic Regulators in the Testis. J Biol Chem. 2013 Nov 29; 288(48):34809-25. PMID: 24121513.
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      23. Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson M, Joung JK. Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins. Nat Biotechnol. 2013 Dec; 31(12):1137-42. PMID: 24108092.
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      24. Richardson ME, Bleiziffer A, Tüttelmann F, Gromoll J, Wilkinson M. Epigenetic regulation of the RHOX homeobox gene cluster and its association with human male infertility. Hum Mol Genet. 2014 Jan 1; 23(1):12-23. PMID: 23943794.
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      25. Karam R, Wengrod J, Gardner LB, Wilkinson M. Regulation of nonsense-mediated mRNA decay: implications for physiology and disease. Biochim Biophys Acta. 2013 Jun-Jul; 1829(6-7):624-33. PMID: 23500037.
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      26. Song HW, Anderson RA, Bayne RA, Gromoll J, Shimasaki S, Chang RJ, Parast MM, Laurent LC, de Rooij DG, Hsieh TC, Wilkinson M. The RHOX homeobox gene cluster is selectively expressed in human oocytes and male germ cells. Hum Reprod. 2013 Jun; 28(6):1635-46. PMID: 23482336.
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      27. Huang L, Wilkinson M. Regulation of nonsense-mediated mRNA decay. Wiley Interdiscip Rev RNA. 2012 Nov-Dec; 3(6):807-28. PMID: 23027648.
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      28. Song HW, Wilkinson M. In vitro spermatogenesis: A long journey to get tails. Spermatogenesis. 2012 Oct 01; 2(4):238-244. PMID: 23248764.
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      29. MacLean JA, Hayashi K, Turner TT, Wilkinson M. The Rhox5 homeobox gene regulates the region-specific expression of its paralogs in the rodent epididymis. Biol Reprod. 2012 Jun; 86(6):189. PMID: 22423045.
        View in: PubMed
      30. Song HW, Dann CT, McCarrey JR, Meistrich ML, Cornwall GA, Wilkinson M. Dynamic expression pattern and subcellular localization of the Rhox10 homeobox transcription factor during early germ cell development. Reproduction. 2012 May; 143(5):611-24. PMID: 22393026.
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      31. Ramaiah M, Shum EY, Wilkinson M. How to activate a gene: decap its associated noncoding RNA. Mol Cell. 2012 Feb 10; 45(3):271-3. PMID: 22325347.
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      32. Bhardwaj A, Song HW, Beildeck M, Kerkhofs S, Castoro R, Shanker S, De Gendt K, Suzuki K, Claessens F, Issa JP, Orgebin-Crist MC, Wilkinson M. DNA demethylation-dependent AR recruitment and GATA factors drive Rhox5 homeobox gene transcription in the epididymis. Mol Endocrinol. 2012 Apr; 26(4):538-49. PMID: 22322598.
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      33. Karam R, Wilkinson M. A conserved microRNA/NMD regulatory circuit controls gene expression. RNA Biol. 2012 Jan; 9(1):22-6. PMID: 22258150.
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      34. Nguyen LS, Jolly L, Shoubridge C, Chan WK, Huang L, Laumonnier F, Raynaud M, Hackett A, Field M, Rodriguez J, Srivastava AK, Lee Y, Long R, Addington AM, Rapoport JL, Suren S, Hahn CN, Gamble J, Wilkinson M, Corbett MA, Gecz J. Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability. Mol Psychiatry. 2012 Nov; 17(11):1103-15. PMID: 22182939.
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      35. Huang L, Lou CH, Chan W, Shum EY, Shao A, Stone E, Karam R, Song HW, Wilkinson M. RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD. Mol Cell. 2011 Sep 16; 43(6):950-61. PMID: 21925383.
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      36. De Gendt K, Denolet E, Willems A, Daniels VW, Clinckemalie L, Denayer S, Wilkinson M, Claessens F, Swinnen JV, Verhoeven G. Expression of Tubb3, a beta-tubulin isotype, is regulated by androgens in mouse and rat Sertoli cells. Biol Reprod. 2011 Nov; 85(5):934-45. PMID: 21734264.
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      37. Bruno IG, Karam R, Huang L, Bhardwaj A, Lou CH, Shum EY, Song HW, Corbett MA, Gifford WD, Gecz J, Pfaff SL, Wilkinson M. Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay. Mol Cell. 2011 May 20; 42(4):500-10. PMID: 21596314.
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      38. Maclean JA, Bettegowda A, Kim BJ, Lou CH, Yang SM, Bhardwaj A, Shanker S, Hu Z, Fan Y, Eckardt S, McLaughlin KJ, Skoultchi AI, Wilkinson M. The rhox homeobox gene cluster is imprinted and selectively targeted for regulation by histone h1 and DNA methylation. Mol Cell Biol. 2011 Mar; 31(6):1275-87. PMID: 21245380.
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      39. Bettegowda A, Wilkinson M. Transcription and post-transcriptional regulation of spermatogenesis. Philos Trans R Soc Lond B Biol Sci. 2010 May 27; 365(1546):1637-51. PMID: 20403875.
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      40. MacLean JA, Wilkinson M. The Rhox genes. Reproduction. 2010 Aug; 140(2):195-213. PMID: 20430877.
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      41. Imam JS, Gudikote JP, Chan WK, Wilkinson M. Frame-disrupting mutations elicit pre-mRNA accumulation independently of frame disruption. Nucleic Acids Res. 2010 Mar; 38(5):1559-74. PMID: 20007599.
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      42. Hu Z, Dandekar D, O'Shaughnessy PJ, De Gendt K, Verhoeven G, Wilkinson M. Androgen-induced Rhox homeobox genes modulate the expression of AR-regulated genes. Mol Endocrinol. 2010 Jan; 24(1):60-75. PMID: 19901196.
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      43. Estrella LA, Wilkinson M, González CI. The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae. J Mol Biol. 2009 Dec 4; 394(3):410-22. PMID: 19733178.
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      44. Chan WK, Bhalla AD, Le Hir H, Nguyen LS, Huang L, Gécz J, Wilkinson M. A UPF3-mediated regulatory switch that maintains RNA surveillance. Nat Struct Mol Biol. 2009 Jul; 16(7):747-53. PMID: 19503078.
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      45. Zhu K, Chan W, Heymach J, Wilkinson M, McConkey DJ. Control of HIF-1alpha expression by eIF2 alpha phosphorylation-mediated translational repression. Cancer Res. 2009 Mar 1; 69(5):1836-43. PMID: 19244104.
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      46. Bhalla AD, Gudikote JP, Wang J, Chan WK, Chang YF, Olivas OR, Wilkinson M. Nonsense codons trigger an RNA partitioning shift. J Biol Chem. 2009 Feb 13; 284(7):4062-72. PMID: 19091751.
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      47. Shanker S, Hu Z, Wilkinson M. Epigenetic regulation and downstream targets of the Rhox5 homeobox gene. Int J Androl. 2008 Sep; 31(5):462-70. PMID: 18637153.
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      48. Karam R, Carvalho J, Bruno I, Graziadio C, Senz J, Huntsman D, Carneiro F, Seruca R, Wilkinson M, Oliveira C. The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers. Oncogene. 2008 Jul 10; 27(30):4255-60. PMID: 18427545.
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      49. Shyu AB, Wilkinson M, van Hoof A. Messenger RNA regulation: to translate or to degrade. EMBO J. 2008 Feb 6; 27(3):471-81. PMID: 18256698.
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      50. Bhardwaj A, Rao MK, Kaur R, Buttigieg MR, Wilkinson M. GATA factors and androgen receptor collaborate to transcriptionally activate the Rhox5 homeobox gene in Sertoli cells. Mol Cell Biol. 2008 Apr; 28(7):2138-53. PMID: 18212046.
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      51. Hu Z, Shanker S, MacLean JA, Ackerman SL, Wilkinson M. The RHOX5 homeodomain protein mediates transcriptional repression of the netrin-1 receptor gene Unc5c. J Biol Chem. 2008 Feb 15; 283(7):3866-76. PMID: 18077458.
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      52. Hu Z, MacLean JA, Bhardwaj A, Wilkinson M. Regulation and function of the Rhox5 homeobox gene. Ann N Y Acad Sci. 2007 Dec; 1120:72-83. PMID: 18184911.
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      53. Chang YF, Chan WK, Imam JS, Wilkinson M. Alternatively spliced T-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame. J Biol Chem. 2007 Oct 12; 282(41):29738-47. PMID: 17693403.
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      54. Chan WK, Huang L, Gudikote JP, Chang YF, Imam JS, MacLean JA, Wilkinson M. An alternative branch of the nonsense-mediated decay pathway. EMBO J. 2007 Apr 4; 26(7):1820-30. PMID: 17363904.
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      55. Chang YF, Imam JS, Wilkinson M. The nonsense-mediated decay RNA surveillance pathway. Annu Rev Biochem. 2007; 76:51-74. PMID: 17352659.
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      56. Bruno I, Wilkinson M. P-bodies react to stress and nonsense. Cell. 2006 Jun 16; 125(6):1036-8. PMID: 16777595.
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      57. Wang W, Cajigas IJ, Peltz SW, Wilkinson M, González CI. Role for Upf2p phosphorylation in Saccharomyces cerevisiae nonsense-mediated mRNA decay. Mol Cell Biol. 2006 May; 26(9):3390-400. PMID: 16611983.
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      58. MacLean JA, Lorenzetti D, Hu Z, Salerno WJ, Miller J, Wilkinson M. Rhox homeobox gene cluster: recent duplication of three family members. Genesis. 2006 Mar; 44(3):122-9. PMID: 16496311.
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      59. Rao MK, Pham J, Imam JS, MacLean JA, Murali D, Furuta Y, Sinha-Hikim AP, Wilkinson M. Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis. Genes Dev. 2006 Jan 15; 20(2):147-52. PMID: 16418481.
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      60. Rao MK, Wilkinson M. Tissue-specific and cell type-specific RNA interference in vivo. Nat Protoc. 2006; 1(3):1494-501. PMID: 17406440.
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      61. Gudikote JP, Imam JS, Garcia RF, Wilkinson M. RNA splicing promotes translation and RNA surveillance. Nat Struct Mol Biol. 2005 Sep; 12(9):801-9. PMID: 16116435.
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      62. MacLean JA, Rao MK, Doyle KM, Richards JS, Wilkinson M. Regulation of the Rhox5 homeobox gene in primary granulosa cells: preovulatory expression and dependence on SP1/SP3 and GABP. Biol Reprod. 2005 Dec; 73(6):1126-34. PMID: 16093360.
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      63. Bhardwaj A, Wilkinson M. A metabolic enzyme doing double duty as a transcription factor. Bioessays. 2005 May; 27(5):467-71. PMID: 15832388.
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      64. Sims-Mourtada JC, Bruce S, McKeller MR, Rangel R, Guzman-Rojas L, Cain K, Lopez C, Zimonjic DB, Popescu NC, Gordon J, Wilkinson M, Martinez-Valdez H. The human AKNA gene expresses multiple transcripts and protein isoforms as a result of alternative promoter usage, splicing, and polyadenylation. DNA Cell Biol. 2005 May; 24(5):325-38. PMID: 15869410.
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      65. Wilkinson M. A new function for nonsense-mediated mRNA-decay factors. Trends Genet. 2005 Mar; 21(3):143-8. PMID: 15734573.
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      66. Maclean JA, Chen MA, Wayne CM, Bruce SR, Rao M, Meistrich ML, Macleod C, Wilkinson M. Rhox: a new homeobox gene cluster. Cell. 2005 Feb 11; 120(3):369-82. PMID: 15707895.
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      67. Maclean JA, Wilkinson M. Gene regulation in spermatogenesis. Curr Top Dev Biol. 2005; 71:131-97. PMID: 16344105.
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      68. Li S, Wilkinson M, Xia X, David M, Xu L, Purkel-Sutton A, Bhardwaj A. Induction of IFN-regulated factors and antitumoral surveillance by transfected placebo plasmid DNA. Mol Ther. 2005 Jan; 11(1):112-9. PMID: 15585412.
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      69. Inoue K, Khajavi M, Ohyama T, Hirabayashi S, Wilson J, Reggin JD, Mancias P, Butler IJ, Wilkinson M, Wegner M, Lupski JR. Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations. Nat Genet. 2004 Apr; 36(4):361-9. PMID: 15004559.
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      70. Wilkinson M. The cycle of nonsense. Mol Cell. 2003 Nov; 12(5):1059-61. PMID: 14636563.
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      71. Rao MK, Wayne CM, Meistrich ML, Wilkinson M. Pem homeobox gene promoter sequences that direct transcription in a Sertoli cell-specific, stage-specific, and androgen-dependent manner in the testis in vivo. Mol Endocrinol. 2003 Feb; 17(2):223-33. PMID: 12554750.
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      72. Wayne CM, Sutton K, Wilkinson M. Expression of the pem homeobox gene in Sertoli cells increases the frequency of adjacent germ cells with deoxyribonucleic acid strand breaks. Endocrinology. 2002 Dec; 143(12):4875-85. PMID: 12446615.
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      73. Wayne CM, MacLean JA, Cornwall G, Wilkinson M. Two novel human X-linked homeobox genes, hPEPP1 and hPEPP2, selectively expressed in the testis. Gene. 2002 Nov 13; 301(1-2):1-11. PMID: 12490318.
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      74. Wang J, Chang YF, Hamilton JI, Wilkinson M. Nonsense-associated altered splicing: a frame-dependent response distinct from nonsense-mediated decay. Mol Cell. 2002 Oct; 10(4):951-7. PMID: 12419238.
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      75. Rao MK, Wayne CM, Wilkinson M. Pem homeobox gene regulatory sequences that direct androgen-dependent developmentally regulated gene expression in different subregions of the epididymis. J Biol Chem. 2002 Dec 13; 277(50):48771-8. PMID: 12351657.
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      76. Wang J, Hamilton JI, Carter MS, Li S, Wilkinson M. Alternatively spliced TCR mRNA induced by disruption of reading frame. Science. 2002 Jul 5; 297(5578):108-10. PMID: 12098701.
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      77. Bühler M, Wilkinson M, Mühlemann O. Intranuclear degradation of nonsense codon-containing mRNA. EMBO Rep. 2002 Jul; 3(7):646-51. PMID: 12101097.
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      78. Wilkinson M, Shyu AB. RNA surveillance by nuclear scanning? Nat Cell Biol. 2002 Jun; 4(6):E144-7. PMID: 12042827.
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      79. Rao MK, Maiti S, Ananthaswamy HN, Wilkinson M. A highly active homeobox gene promoter regulated by Ets and Sp1 family members in normal granulosa cells and diverse tumor cell types. J Biol Chem. 2002 Jul 19; 277(29):26036-45. PMID: 11986330.
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      80. Wang J, Vock VM, Li S, Olivas OR, Wilkinson M. A quality control pathway that down-regulates aberrant T-cell receptor (TCR) transcripts by a mechanism requiring UPF2 and translation. J Biol Chem. 2002 May 24; 277(21):18489-93. PMID: 11889124.
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      81. Wang J, Han Y, Liang S, Wilkinson M. Catalytic antibody therapy against the insecticide carbaryl. Biochem Biophys Res Commun. 2002 Mar 1; 291(3):605-10. PMID: 11855832.
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      82. Wang J, Gudikote JP, Olivas OR, Wilkinson M. Boundary-independent polar nonsense-mediated decay. EMBO Rep. 2002 Mar; 3(3):274-9. PMID: 11850396.
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      83. Gudikote JP, Wilkinson M. T-cell receptor sequences that elicit strong down-regulation of premature termination codon-bearing transcripts. EMBO J. 2002 Jan 15; 21(1-2):125-34. PMID: 11782432.
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      84. Wang J, Han Y, Wilkinson M. An active immunization approach to generate protective catalytic antibodies. Biochem J. 2001 Nov 15; 360(Pt 1):151-7. PMID: 11696002.
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      85. Wang J, Wilkinson M. Deletion mutagenesis of large (12-kb) plasmids by a one-step PCR protocol. Biotechniques. 2001 Oct; 31(4):722-4. PMID: 11680696.
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      86. Wilkinson M, Shyu AB. Multifunctional regulatory proteins that control gene expression in both the nucleus and the cytoplasm. Bioessays. 2001 Sep; 23(9):775-87. PMID: 11536290.
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      87. Mühlemann O, Mock-Casagrande CS, Wang J, Li S, Custódio N, Carmo-Fonseca M, Wilkinson M, Moore MJ. Precursor RNAs harboring nonsense codons accumulate near the site of transcription. Mol Cell. 2001 Jul; 8(1):33-43. PMID: 11511358.
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      88. Maiti S, Meistrich ML, Wilson G, Shetty G, Marcelli M, McPhaul MJ, Morris PL, Wilkinson M. Irradiation selectively inhibits expression from the androgen-dependent Pem homeobox gene promoter in sertoli cells. Endocrinology. 2001 Apr; 142(4):1567-77. PMID: 11250938.
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      89. Clement JQ, Maiti S, Wilkinson M. Localization and stability of introns spliced from the Pem homeobox gene. J Biol Chem. 2001 May 18; 276(20):16919-30. PMID: 11278282.
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      90. Wang J, Wilkinson M. Site-directed mutagenesis of large (13-kb) plasmids in a single-PCR procedure. Biotechniques. 2000 Nov; 29(5):976-8. PMID: 11084857.
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      91. Shyu AB, Wilkinson M. The double lives of shuttling mRNA binding proteins. Cell. 2000 Jul 21; 102(2):135-8. PMID: 10943833.
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      92. Clement JQ, Wilkinson M. Rapid induction of nuclear transcripts and inhibition of intron decay in response to the polymerase II inhibitor DRB. J Mol Biol. 2000 Jun 23; 299(5):1179-91. PMID: 10873444.
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      93. Clement JQ, Qian L, Kaplinsky N, Wilkinson M. The stability and fate of a spliced intron from vertebrate cells. RNA. 1999 Feb; 5(2):206-20. PMID: 10024173.
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      94. Misteli T, Cáceres JF, Clement JQ, Krainer AR, Wilkinson M, Spector DL. Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo. J Cell Biol. 1998 Oct 19; 143(2):297-307. PMID: 9786943.
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      95. Sutton KA, Vu MN, Wilkinson M. Distal V beta promoters transcribe novel T-cell receptor-beta transcripts in early development. Immunology. 1998 Feb; 93(2):213-20. PMID: 9616371.
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      96. Li S, Wilkinson M. Nonsense surveillance in lymphocytes? Immunity. 1998 Feb; 8(2):135-41. PMID: 9491995.
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      97. Sutton KA, Maiti S, Tribley WA, Lindsey JS, Meistrich ML, Bucana CD, Sanborn BM, Joseph DR, Griswold MD, Cornwall GA, Wilkinson M. Androgen regulation of the Pem homeodomain gene in mice and rat Sertoli and epididymal cells. J Androl. 1998 Jan-Feb; 19(1):21-30. PMID: 9537288.
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