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    Andrew Baird

    TitleProfessor In Residence
    SchoolUniversity of California, San Diego
    DepartmentSurgery
    Phone619-471-9027
    Emailanbaird@ucsd.edu
    vCardDownload vCard

      Collapse Biography 
      Collapse Education and Training
      Salk InstitutePost-doctoral Fellow1982Neuroendocrinology
      McGill UniversityPh.D. 1980Biochemistry
      University of OttawaHons. B.Sc. 1976Biochemistry
      University of OttawaB.Sc.1975Biochemistry

      Collapse Overview 
      Collapse Overview
      Although it is widely accepted that the presence of taxonomically-restricted genes in different species make those genomes unique from all other species, it is not known if, or how, these species-specific genes might confer species-specific biological responsiveness to fundamental processes like inflammation and fibrosis.

      Our laboratories have shown how the emergence of uniquely-human genes during hominid evolution may contribute to the appearance and progression of complex human inflammatory diseases.

      First, we showed that uniquely-human genes are over-represented and regulated in immune cells like monocytes, lymphocytes and progenitor cells of bone marrow.

      Second, we showed how the open reading frames encoded by these genes (once thought to be “pseudogenes”) can produce species-specific ligands (e.g. c2orf40TRG), receptors (e.g. CHRFAM7A), signal transduction molecules (e.g. TBC1D3) and even candidate transcription factors (e.g. TPTEP1).

      Finally, we also showed how each of these genes can be implicated in human inflammatory disease, from injury and regeneration to cancer and tissue repair.

      Having shown that these genes can have new biological activities unto themselves, gauge the activities of genes common to all species or compensate for the activity of their “parental” gene(s), we are evaluating how they arise and what they do in the hominid genome.

      The mechanisms that explain their appearance in the human genome are common to all species. They include
      (1) mutagenesis,
      (2) partial gene duplication and rearrangement,
      (3) differential mRNA splicing and,
      (4) the endogenization of foreign DNA.

      Their effects on human biology include modulating human monocytes, lymphocytes and epithelial cell migration and trafficking, altering responsiveness to secretogogues, changing the drug sensitivity of human cells, alter resilience and inhibiting colony formation.

      Because uniquely-human genes have the potential to create uniquely human signaling pathways that, by definition are absent in other species, we propose that their identity, their expression and their contributions to human disease need to be better understood so as to fully understand the development, progression and resolution of human inflammatory disease and the mechanisms that govern human tissue repair and regeneration.

      1: Baird A, Costantini T, Coimbra R, Eliceiri BP. Injury, inflammation and the emergence of human-specific genes. Wound Repair Regen. 2016 May;24(3):602-6. doi: 10.1111/wrr.12422. Epub 2016 Apr 4. PubMed PMID: 26874655.
      2: Costantini TW, Dang X, Coimbra R, Eliceiri BP, Baird A. CHRFAM7A, a human-specific and partially duplicated a7-nicotinic acetylcholine receptor gene with the potential to specify a human-specific inflammatory response to injury. Leukoc Biol. 2015 Feb;97(2):247-57. doi: 10.1189/jlb.4RU0814-381R. PubMed PMID: 25473097
      3: Costantini TW, Dang X, Yurchyshyna MV, Coimbra R, Eliceiri BP, Baird A. A Human-Specific a7-Nicotinic Acetylcholine Receptor Gene in Human Leukocytes: Identification, Regulation and the Consequences of CHRFAM7A Expression. Mol Med. 2015 Apr 3;21:323-36. doi: 10.2119/molmed.2015.00018. PubMed PMID: 25860877
      4: Baird A, Coimbra R, Dang X, Eliceiri BP, Costantini TW. Up-regulation of the human-specific CHRFAM7A gene in inflammatory bowel disease. BBA Clin. 2016 Jan;5:66-71. doi: 10.1016/j.bbacli.2015.12.003. eCollection 2016 Jun. PubMed PMID:27051591
      5: Dang X, Eliceiri BP, Baird A, Costantini TW. CHRFAM7A: a human-specific 7-nicotinic acetylcholine receptor gene shows differential responsiveness of human intestinal epithelial cells to LPS. FASEB J. 2015 Jun;29(6):2292-302. doi: 10.1096/fj.14-268037. Epub 2015 Feb 13. PubMed PMID: 25681457
      6: Costantini TW, Meads M, Dang X, Coimbra R, Torbett BE, Baird A, Eliceiri BP. The Response to Burn Injury in Mice With Human Hematolymphoid Systems. Ann Surg. 2016 Jan;263(1):199-204. doi: 10.1097/SLA.0000000000001123. PubMed PMID:25575256.


      Collapse Research 
      Collapse Research Activities and Funding
      Targeting the choroid plexus for drug translocation into CSF
      NIH/NEI R21EY018479Sep 30, 2007 - Dec 31, 2010
      Role: Principal Investigator
      A Combinatorial Approach to Wound Healing for Protein, Gene and Cell Therapeutics
      NIH/NIGMS P20GM078421Aug 1, 2006 - Jul 31, 2011
      Role: Principal Investigator
      Directed Delivery of Growth Factors to the CNS
      NIH/NINDS R43NS051896Jul 15, 2005 - Jun 30, 2006
      Role: Principal Investigator
      SMALL INSTRUMENTATION GRANT
      NIH/NIDDK S15DK049155Aug 1, 1994 - Jul 31, 1995
      Role: Principal Investigator
      BRAIN PEPTIDES IN PITUITARY FUNCTIONS AND DIABETES
      NIH/NIDDK P01DK018811Jun 30, 1975 - Apr 30, 1996
      Role: Co-Principal Investigator

      Collapse ORNG Applications 
      Collapse Featured Publications
      Collapse Websites

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Baird A, Deng C, Eliceiri MH, Haghi F, Dang X, Coimbra R, Costantini TW, Torbett BE, Eliceiri BP. Mice engrafted with human hematopoietic stem cells support a human myeloid cell inflammatory response in vivo. Wound Repair Regen. 2016 Nov; 24(6):1004-1014. PMID: 27663454.
        View in: PubMed
      2. Costantini TW, Baird A. Lost your nerve? Modulating the parasympathetic nervous system to treat inflammatory bowel disease. J Physiol. 2016 Aug 01; 594(15):4097-8. PMID: 27477606; PMCID: PMC4967743 [Available on 08/01/17].
      3. Baird A, Costantini T, Coimbra R, Eliceiri BP. Injury, inflammation and the emergence of human-specific genes. Wound Repair Regen. 2016 May; 24(3):602-6. PMID: 26874655; PMCID: PMC5021143.
      4. Podvin S, Miller MC, Rossi R, Chukwueke J, Donahue JE, Johanson CE, Baird A, Stopa EG. The Orphan C2orf40 Gene is a Neuroimmune Factor in Alzheimer's Disease. JSM Alzheimers Dis Relat Dement. 2016; 3(1). PMID: 27990492.
        View in: PubMed
      5. Kurabi A, Pak KK, Bernhardt M, Baird A, Ryan AF. Discovery of a Biological Mechanism of Active Transport through the Tympanic Membrane to the Middle Ear. Sci Rep. 2016 Mar 07; 6:22663. PMID: 26946957; PMCID: PMC4780071.
      6. Baird A, Coimbra R, Dang X, Eliceiri BP, Costantini TW. Up-regulation of the human-specific CHRFAM7A gene in inflammatory bowel disease. BBA Clin. 2016 Jun; 5:66-71. PMID: 27051591; PMCID: PMC4802402.
      7. Costantini TW, Meads M, Dang X, Coimbra R, Torbett BE, Baird A, Eliceiri BP. The Response to Burn Injury in Mice With Human Hematolymphoid Systems. Ann Surg. 2016 Jan; 263(1):199-204. PMID: 25575256.
        View in: PubMed
      8. Costantini TW, Coimbra R, Lopez NE, Lee JG, Potenza B, Smith A, Baird A, Eliceiri BP. Monitoring Neutrophil-Expressed Cell Surface Esophageal Cancer Related Gene-4 after Severe Burn Injury. Surg Infect (Larchmt). 2015 Dec; 16(6):669-74. PMID: 26460850; PMCID: PMC4663648 [Available on 12/01/16].
      9. Costantini TW, Dang X, Yurchyshyna MV, Coimbra R, Eliceiri BP, Baird A. A Human-Specific a7-Nicotinic Acetylcholine Receptor Gene in Human Leukocytes: Identification, Regulation and the Consequences of CHRFAM7A Expression. Mol Med. 2015 Apr 03; 21:323-36. PMID: 25860877; PMCID: PMC4534468.
      10. Torbett BE, Baird A, Eliceiri BP. Understanding the rules of the road: proteomic approaches to interrogate the blood brain barrier. Front Neurosci. 2015; 9:70. PMID: 25788875; PMCID: PMC4349081.
      11. Dang X, Eliceiri BP, Baird A, Costantini TW. CHRFAM7A: a human-specific a7-nicotinic acetylcholine receptor gene shows differential responsiveness of human intestinal epithelial cells to LPS. FASEB J. 2015 Jun; 29(6):2292-302. PMID: 25681457; PMCID: PMC4763870.
      12. Podvin S, Dang X, Meads M, Kurabi A, Costantini T, Eliceiri BP, Baird A, Coimbra R. Esophageal cancer-related gene-4 (ECRG4) interactions with the innate immunity receptor complex. Inflamm Res. 2015 Feb; 64(2):107-18. PMID: 25511108; PMCID: PMC4301958.
      13. Kao S, Shaterian A, Cauvi DM, Dang X, Chun HB, De Maio A, Costantini TW, Coimbra R, Eliceiri BP, Baird A. Pulmonary preconditioning, injury, and inflammation modulate expression of the candidate tumor suppressor gene ECRG4 in lung. Exp Lung Res. 2015 Apr; 41(3):162-72. PMID: 25513848; PMCID: PMC4524537.
      14. Costantini TW, Dang X, Coimbra R, Eliceiri BP, Baird A. CHRFAM7A, a human-specific and partially duplicated a7-nicotinic acetylcholine receptor gene with the potential to specify a human-specific inflammatory response to injury. J Leukoc Biol. 2015 Feb; 97(2):247-57. PMID: 25473097; PMCID: PMC4304420.
      15. Baird A, Nowak S. Why primary care practices should become digital health information hubs for their patients. BMC Fam Pract. 2014 Nov 25; 15:190. PMID: 25421733; PMCID: PMC4247781.
      16. Lee J, Dang X, Borboa A, Coimbra R, Baird A, Eliceiri BP. Thrombin-processed Ecrg4 recruits myeloid cells and induces antitumorigenic inflammation. Neuro Oncol. 2015 May; 17(5):685-96. PMID: 25378632; PMCID: PMC4482854.
      17. Baird A, Lee J, Podvin S, Kurabi A, Dang X, Coimbra R, Costantini T, Bansal V, Eliceiri BP. Esophageal cancer-related gene 4 at the interface of injury, inflammation, infection, and malignancy. Gastrointest Cancer. 2014; 2014(4):131-142. PMID: 25580077.
        View in: PubMed
      18. Lee J, Baird A, Eliceiri BP. Vascular normalization in cerebral angiogenesis: friend or foe? Methods Mol Biol. 2014; 1135:25-34. PMID: 24510852; PMCID: PMC4524516.
      19. Kurabi A, Pak K, Dang X, Coimbra R, Eliceiri BP, Ryan AF, Baird A. Ecrg4 attenuates the inflammatory proliferative response of mucosal epithelial cells to infection. PLoS One. 2013; 8(4):e61394. PMID: 23626679; PMCID: PMC3634077.
      20. Costantini TW, Eliceiri BP, Putnam JG, Bansal V, Baird A, Coimbra R. Intravenous phage display identifies peptide sequences that target the burn-injured intestine. Peptides. 2012 Nov; 38(1):94-9. PMID: 22960048; PMCID: PMC4524536.
      21. Shaterian A, Kao S, Chen L, DiPietro LA, Coimbra R, Eliceiri BP, Baird A. The candidate tumor suppressor gene Ecrg4 as a wound terminating factor in cutaneous injury. Arch Dermatol Res. 2013 Mar; 305(2):141-9. PMID: 22899245; PMCID: PMC3510341.
      22. Lopez NE, Krzyzaniak M, Costantini TW, De Maio A, Baird A, Eliceiri BP, Coimbra R. Vagal nerve stimulation blocks peritoneal macrophage inflammatory responsiveness after severe burn injury. Shock. 2012 Aug; 38(3):294-300. PMID: 22683732; PMCID: PMC3422402.
      23. Ortiz-Pomales YT, Krzyzaniak M, Coimbra R, Baird A, Eliceiri BP. Vagus nerve stimulation blocks vascular permeability following burn in both local and distal sites. Burns. 2013 Feb; 39(1):68-75. PMID: 22694873; PMCID: PMC3443518.
      24. Dang X, Podvin S, Coimbra R, Eliceiri B, Baird A. Cell-specific processing and release of the hormone-like precursor and candidate tumor suppressor gene product, Ecrg4. Cell Tissue Res. 2012 Jun; 348(3):505-14. PMID: 22526622; PMCID: PMC3367106.
      25. Kao S, Mo J, Baird A, Eliceiri BP. Basic fibroblast growth factor in an animal model of spontaneous mammary tumor progression. Oncol Rep. 2012 Jun; 27(6):1807-14. PMID: 22407271; PMCID: PMC4224275.
      26. Baird A, Coimbra R, Dang X, Lopez N, Lee J, Krzyzaniak M, Winfield R, Potenza B, Eliceiri BP. Cell surface localization and release of the candidate tumor suppressor Ecrg4 from polymorphonuclear cells and monocytes activate macrophages. J Leukoc Biol. 2012 May; 91(5):773-81. PMID: 22396620; PMCID: PMC3336773.
      27. Krzyzaniak M, Ortiz-Pomales Y, Lopez N, Reys LG, Cheadle G, Wolf P, Eliceiri B, Bansal V, Baird A, Coimbra R. CPSI-121 pharmacologically prevents intestinal barrier dysfunction after cutaneous burn through a vagus nerve-dependent mechanism. J Trauma Acute Care Surg. 2012 Feb; 72(2):355-61; discussion 361-3. PMID: 22327977; PMCID: PMC4251782.
      28. Bansal V, Ryu SY, Lopez N, Allexan S, Krzyzaniak M, Eliceiri B, Baird A, Coimbra R. Vagal stimulation modulates inflammation through a ghrelin mediated mechanism in traumatic brain injury. Inflammation. 2012 Feb; 35(1):214-20. PMID: 21360048; PMCID: PMC3282000.
      29. Podvin S, Gonzalez AM, Miller MC, Dang X, Botfield H, Donahue JE, Kurabi A, Boissaud-Cooke M, Rossi R, Leadbeater WE, Johanson CE, Coimbra R, Stopa EG, Eliceiri BP, Baird A. Esophageal cancer related gene-4 is a choroid plexus-derived injury response gene: evidence for a biphasic response in early and late brain injury. PLoS One. 2011; 6(9):e24609. PMID: 21935431; PMCID: PMC3173480.
      30. Baird A. Gene transfer into Mammalian cells using targeted filamentous bacteriophage. Cold Spring Harb Protoc. 2011 Aug 01; 2011(8):950-7. PMID: 21807851; PMCID: PMC4251578.
      31. Chun HB, Scott M, Niessen S, Hoover H, Baird A, Yates J, Torbett BE, Eliceiri BP. The proteome of mouse brain microvessel membranes and basal lamina. J Cereb Blood Flow Metab. 2011 Dec; 31(12):2267-81. PMID: 21792245; PMCID: PMC3323187.
      32. Krzyzaniak MJ, Peterson CY, Cheadle G, Loomis W, Wolf P, Kennedy V, Putnam JG, Bansal V, Eliceiri B, Baird A, Coimbra R. Efferent vagal nerve stimulation attenuates acute lung injury following burn: The importance of the gut-lung axis. Surgery. 2011 Sep; 150(3):379-89. PMID: 21783215; PMCID: PMC4251587.
      33. Shaterian A, Borboa A, Coimbra R, Baird A, Eliceiri BP. Non-invasive detection of spatio-temporal activation of SBE and NFAT5 promoters in transgenic reporter mice following stroke. Neuropathology. 2012 Apr; 32(2):118-23. PMID: 21749466; PMCID: PMC3193877.
      34. Krzyzaniak M, Cheadle G, Peterson C, Loomis W, Putnam J, Wolf P, Baird A, Eliceiri B, Bansal V, Coimbra R. Burn-induced acute lung injury requires a functional Toll-like receptor 4. Shock. 2011 Jul; 36(1):24-9. PMID: 21330948; PMCID: PMC4241238.
      35. Krzyzaniak M, Peterson C, Loomis W, Hageny AM, Wolf P, Reys L, Putnam J, Eliceiri B, Baird A, Bansal V, Coimbra R. Postinjury vagal nerve stimulation protects against intestinal epithelial barrier breakdown. J Trauma. 2011 May; 70(5):1168-75; discussion 1175-6. PMID: 21610431; PMCID: PMC4241239.
      36. Sawada R, Peterson CY, Gonzalez AM, Potenza BM, Mueller B, Coimbra R, Eliceiri BP, Baird A. A phage-targeting strategy for the design of spatiotemporal drug delivery from grafted matrices. Fibrogenesis Tissue Repair. 2011 Feb 17; 4:7. PMID: 21329515; PMCID: PMC3050739.
      37. Huang D, Licuanan WY, Baird A, Fukami H. Cleaning up the 'Bigmessidae': molecular phylogeny of scleractinian corals from Faviidae, Merulinidae, Pectiniidae and Trachyphylliidae. BMC Evol Biol. 2011 Feb 07; 11:37. PMID: 21299898; PMCID: PMC3042006.
      38. Lee J, Borboa AK, Baird A, Eliceiri BP. Non-invasive quantification of brain tumor-induced astrogliosis. BMC Neurosci. 2011 Jan 19; 12:9. PMID: 21247490; PMCID: PMC3033849.
      39. Gonzalez AM, Podvin S, Lin SY, Miller MC, Botfield H, Leadbeater WE, Roberton A, Dang X, Knowling SE, Cardenas-Galindo E, Donahue JE, Stopa EG, Johanson CE, Coimbra R, Eliceiri BP, Baird A. Ecrg4 expression and its product augurin in the choroid plexus: impact on fetal brain development, cerebrospinal fluid homeostasis and neuroprogenitor cell response to CNS injury. Fluids Barriers CNS. 2011 Jan 18; 8(1):6. PMID: 21349154; PMCID: PMC3042980.
      40. Gonzalez AM, Leadbeater WE, Burg M, Sims K, Terasaki T, Johanson CE, Stopa EG, Eliceiri BP, Baird A. Targeting choroid plexus epithelia and ventricular ependyma for drug delivery to the central nervous system. BMC Neurosci. 2011 Jan 07; 12:4. PMID: 21214926; PMCID: PMC3025905.
      41. Baird A, Eliceiri BP, Gonzalez AM, Johanson CE, Leadbeater W, Stopa EG. Targeting the choroid plexus-CSF-brain nexus using peptides identified by phage display. Methods Mol Biol. 2011; 686:483-98. PMID: 21082389; PMCID: PMC4224277.
      42. Lee J, Baird A, Eliceiri BP. In vivo measurement of glioma-induced vascular permeability. Methods Mol Biol. 2011; 763:417-22. PMID: 21874468; PMCID: PMC4251581.
      43. Eliceiri BP, Gonzalez AM, Baird A. Zebrafish model of the blood-brain barrier: morphological and permeability studies. Methods Mol Biol. 2011; 686:371-8. PMID: 21082382; PMCID: PMC4222041.
      44. Lee J, Borboa AK, Chun HB, Baird A, Eliceiri BP. Conditional deletion of the focal adhesion kinase FAK alters remodeling of the blood-brain barrier in glioma. Cancer Res. 2010 Dec 15; 70(24):10131-40. PMID: 21159635; PMCID: PMC3059220.
      45. Bansal V, Ryu SY, Blow C, Costantini T, Loomis W, Eliceiri B, Baird A, Wolf P, Coimbra R. The hormone ghrelin prevents traumatic brain injury induced intestinal dysfunction. J Neurotrauma. 2010 Dec; 27(12):2255-60. PMID: 20858122; PMCID: PMC3304249.
      46. Johanson C, Stopa E, Baird A, Sharma H. Traumatic brain injury and recovery mechanisms: peptide modulation of periventricular neurogenic regions by the choroid plexus-CSF nexus. J Neural Transm (Vienna). 2011 Jan; 118(1):115-33. PMID: 20936524; PMCID: PMC3026679.
      47. Gonzalez AM, Leadbeater W, Podvin S, Borboa A, Burg M, Sawada R, Rayner J, Sims K, Terasaki T, Johanson C, Stopa E, Eliceiri B, Baird A. Epidermal growth factor targeting of bacteriophage to the choroid plexus for gene delivery to the central nervous system via cerebrospinal fluid. Brain Res. 2010 Nov 04; 1359:1-13. PMID: 20732308; PMCID: PMC2955767.
      48. Gonzalez AM, Taylor WM, Johanson CE, King JC, Leadbeater WE, Stopa EG, Baird A. Co-localization and regulation of basic fibroblast growth factor and arginine vasopressin in neuroendocrine cells of the rat and human brain. Cerebrospinal Fluid Res. 2010 Aug 13; 7:13. PMID: 20707896; PMCID: PMC2927497.
      49. Costantini TW, Bansal V, Krzyzaniak M, Putnam JG, Peterson CY, Loomis WH, Wolf P, Baird A, Eliceiri BP, Coimbra R. Vagal nerve stimulation protects against burn-induced intestinal injury through activation of enteric glia cells. Am J Physiol Gastrointest Liver Physiol. 2010 Dec; 299(6):G1308-18. PMID: 20705905; PMCID: PMC3774266.
      50. Costantini TW, Bansal V, Peterson CY, Loomis WH, Putnam JG, Rankin F, Wolf P, Eliceiri BP, Baird A, Coimbra R. Efferent vagal nerve stimulation attenuates gut barrier injury after burn: modulation of intestinal occludin expression. J Trauma. 2010 Jun; 68(6):1349-54; discussion 1354-6. PMID: 20539179; PMCID: PMC4251593.
      51. Bansal V, Costantini T, Ryu SY, Peterson C, Loomis W, Putnam J, Elicieri B, Baird A, Coimbra R. Stimulating the central nervous system to prevent intestinal dysfunction after traumatic brain injury. J Trauma. 2010 May; 68(5):1059-64. PMID: 20453760; PMCID: PMC4251579.
      52. Peterson CY, Costantini TW, Loomis WH, Putnam JG, Wolf P, Bansal V, Eliceiri BP, Baird A, Coimbra R. Toll-like receptor-4 mediates intestinal barrier breakdown after thermal injury. Surg Infect (Larchmt). 2010 Apr; 11(2):137-44. PMID: 20374005; PMCID: PMC3304242.
      53. Costantini TW, Eliceiri BP, Peterson CY, Loomis WH, Putnam JG, Baird A, Wolf P, Bansal V, Coimbra R. Quantitative assessment of intestinal injury using a novel in vivo, near-infrared imaging technique. Mol Imaging. 2010 Feb; 9(1):30-9. PMID: 20128996; PMCID: PMC4241240.
      54. Costantini TW, Peterson CY, Kroll L, Loomis WH, Putnam JG, Wolf P, Eliceiri BP, Baird A, Bansal V, Coimbra R. Burns, inflammation, and intestinal injury: protective effects of an anti-inflammatory resuscitation strategy. J Trauma. 2009 Dec; 67(6):1162-8. PMID: 20009662; PMCID: PMC4251580.
      55. Peterson CY, Shaterian A, Borboa AK, Gonzalez AM, Potenza BM, Coimbra R, Eliceiri BP, Baird A. The noninvasive, quantitative, in vivo assessment of adenoviral-mediated gene delivery in skin wound biomaterials. Biomaterials. 2009 Dec; 30(35):6788-93. PMID: 19781761; PMCID: PMC2948440.
      56. Costantini TW, Putnam JG, Sawada R, Baird A, Loomis WH, Eliceiri BP, Bansal V, Coimbra R. Targeting the gut barrier: identification of a homing peptide sequence for delivery into the injured intestinal epithelial cell. Surgery. 2009 Aug; 146(2):206-12. PMID: 19628075; PMCID: PMC4251594.
      57. Gonzalez AM, Berlanga O, Leadbeater WE, Cooper-Charles L, Sims K, Logan A, Eliceiri B, Berry M, Baird A. The deployment of adenovirus-containing gene activated matrices onto severed axons after central nervous system injury leads to transgene expression in target neuronal cell bodies. J Gene Med. 2009 Aug; 11(8):679-88. PMID: 19507166; PMCID: PMC4241242.
      58. Bansal V, Costantini T, Kroll L, Peterson C, Loomis W, Eliceiri B, Baird A, Wolf P, Coimbra R. Traumatic brain injury and intestinal dysfunction: uncovering the neuro-enteric axis. J Neurotrauma. 2009 Aug; 26(8):1353-9. PMID: 19344293; PMCID: PMC2989839.
      59. Lee J, Lund-Smith C, Borboa A, Gonzalez AM, Baird A, Eliceiri BP. Glioma-induced remodeling of the neurovascular unit. Brain Res. 2009 Sep 08; 1288:125-34. PMID: 19595677; PMCID: PMC2735571.
      60. Shaterian A, Borboa A, Sawada R, Costantini T, Potenza B, Coimbra R, Baird A, Eliceiri BP. Real-time analysis of the kinetics of angiogenesis and vascular permeability in an animal model of wound healing. Burns. 2009 Sep; 35(6):811-7. PMID: 19423227; PMCID: PMC2739287.
      61. Costantini TW, Peterson CY, Kroll L, Loomis WH, Eliceiri BP, Baird A, Bansal V, Coimbra R. Role of p38 MAPK in burn-induced intestinal barrier breakdown. J Surg Res. 2009 Sep; 156(1):64-9. PMID: 19577248; PMCID: PMC4251589.
      62. Costantini TW, Loomis WH, Putnam JG, Drusinsky D, Deree J, Choi S, Wolf P, Baird A, Eliceiri B, Bansal V, Coimbra R. Burn-induced gut barrier injury is attenuated by phosphodiesterase inhibition: effects on tight junction structural proteins. Shock. 2009 Apr; 31(4):416-22. PMID: 18791495; PMCID: PMC3445035.
      63. Costantini TW, Loomis WH, Putnam JG, Kroll L, Eliceiri BP, Baird A, Bansal V, Coimbra R. Pentoxifylline modulates intestinal tight junction signaling after burn injury: effects on myosin light chain kinase. J Trauma. 2009 Jan; 66(1):17-24; discussion 24-5. PMID: 19131801; PMCID: PMC4251583.
      64. Costantini TW, Deree J, Loomis W, Putnam JG, Choi S, Baird A, Eliceiri BP, Bansal V, Coimbra R. Phosphodiesterase inhibition attenuates alterations to the tight junction proteins occludin and ZO-1 in immunostimulated Caco-2 intestinal monolayers. Life Sci. 2009 Jan 02; 84(1-2):18-22. PMID: 18992758.
        View in: PubMed
      65. Gonzalez AM, Berry M, Greenlees L, Logan A, Baird A. Matrix-mediated gene transfer to brain cortex and dorsal root ganglion neurones by retrograde axonal transport after dorsal column lesion. J Gene Med. 2006 Jul; 8(7):901-9. PMID: 16718733.
        View in: PubMed
      66. Logan A, Ahmed Z, Baird A, Gonzalez AM, Berry M. Neurotrophic factor synergy is required for neuronal survival and disinhibited axon regeneration after CNS injury. Brain. 2006 Feb; 129(Pt 2):490-502. PMID: 16339795.
        View in: PubMed
      67. Johanson CE, Duncan JA, Stopa EG, Baird A. Enhanced prospects for drug delivery and brain targeting by the choroid plexus-CSF route. Pharm Res. 2005 Jul; 22(7):1011-37. PMID: 16028003.
        View in: PubMed
      68. Burg M, Ravey EP, Gonzales M, Amburn E, Faix PH, Baird A, Larocca D. Selection of internalizing ligand-display phage using rolling circle amplification for phage recovery. DNA Cell Biol. 2004 Jul; 23(7):457-62. PMID: 15294095.
        View in: PubMed
      69. Faix PH, Burg MA, Gonzales M, Ravey EP, Baird A, Larocca D. Phage display of cDNA libraries: enrichment of cDNA expression using open reading frame selection. Biotechniques. 2004 Jun; 36(6):1018-22, 1024, 1026-9. PMID: 15211753.
        View in: PubMed
      70. Barrett LB, Berry M, Ying WB, Hodgkin MN, Seymour LW, Gonzalez AM, Read ML, Baird A, Logan A. CTb targeted non-viral cDNA delivery enhances transgene expression in neurons. J Gene Med. 2004 Apr; 6(4):429-38. PMID: 15079817.
        View in: PubMed
      71. Larocca D, Burg MA, Jensen-Pergakes K, Ravey EP, Gonzalez AM, Baird A. Evolving phage vectors for cell targeted gene delivery. Curr Pharm Biotechnol. 2002 Mar; 3(1):45-57. PMID: 11883506.
        View in: PubMed
      72. Burg MA, Jensen-Pergakes K, Gonzalez AM, Ravey P, Baird A, Larocca D. Enhanced phagemid particle gene transfer in camptothecin-treated carcinoma cells. Cancer Res. 2002 Feb 15; 62(4):977-81. PMID: 11861367.
        View in: PubMed
      73. Larocca D, Jensen-Pergakes K, Burg MA, Baird A. Gene transfer using targeted filamentous bacteriophage. Methods Mol Biol. 2002; 185:393-401. PMID: 11769003.
        View in: PubMed
      74. Larocca D, Baird A. Receptor-mediated gene transfer by phage-display vectors: applications in functional genomics and gene therapy. Drug Discov Today. 2001 Aug 01; 6(15):793-801. PMID: 11470588.
        View in: PubMed
      75. Berry M, Barrett L, Seymour L, Baird A, Logan A. Gene therapy for central nervous system repair. Curr Opin Mol Ther. 2001 Aug; 3(4):338-49. PMID: 11525557.
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      76. Larocca D, Jensen-Pergakes K, Burg MA, Baird A. Receptor-targeted gene delivery using multivalent phagemid particles. Mol Ther. 2001 Apr; 3(4):476-84. PMID: 11319907.
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      77. Berry M, Gonzalez AM, Clarke W, Greenlees L, Barrett L, Tsang W, Seymour L, Bonadio J, Logan A, Baird A. Sustained effects of gene-activated matrices after CNS injury. Mol Cell Neurosci. 2001 Apr; 17(4):706-16. PMID: 11312606.
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      78. Stopa EG, Berzin TM, Kim S, Song P, Kuo-LeBlanc V, Rodriguez-Wolf M, Baird A, Johanson CE. Human choroid plexus growth factors: What are the implications for CSF dynamics in Alzheimer's disease? Exp Neurol. 2001 Jan; 167(1):40-7. PMID: 11161591.
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      79. Sudhoff H, Dazert S, Gonzales AM, Borkowski G, Park SY, Baird A, Hildmann H, Ryan AF. Angiogenesis and angiogenic growth factors in middle ear cholesteatoma. Am J Otol. 2000 Nov; 21(6):793-8. PMID: 11078065.
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      80. Trudel C, Faure-Desire V, Florkiewicz RZ, Baird A. Translocation of FGF2 to the cell surface without release into conditioned media. J Cell Physiol. 2000 Nov; 185(2):260-8. PMID: 11025448.
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      81. Barrett LB, Logan A, Berry M, Ying W, Gonzalez AM, Baird A, Seymour LW. Targeted transfection of neuronal cells using a poly(D-lysine)-cholera-toxin b chain conjugate. Biochem Soc Trans. 1999 Dec; 27(6):851-7. PMID: 10830116.
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      82. Kassner PD, Burg MA, Baird A, Larocca D. Genetic selection of phage engineered for receptor-mediated gene transfer to mammalian cells. Biochem Biophys Res Commun. 1999 Nov 02; 264(3):921-8. PMID: 10544031.
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      83. Logan A, Baird A, Berry M. Decorin attenuates gliotic scar formation in the rat cerebral hemisphere. Exp Neurol. 1999 Oct; 159(2):504-10. PMID: 10506521.
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      84. Doukas J, Hoganson DK, Ong M, Ying W, Lacey DL, Baird A, Pierce GF, Sosnowski BA. Retargeted delivery of adenoviral vectors through fibroblast growth factor receptors involves unique cellular pathways. FASEB J. 1999 Aug; 13(11):1459-66. PMID: 10428769.
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      85. Johanson CE, Szmydynger-Chodobska J, Chodobski A, Baird A, McMillan P, Stopa EG. Altered formation and bulk absorption of cerebrospinal fluid in FGF-2-induced hydrocephalus. Am J Physiol. 1999 Jul; 277(1 Pt 2):R263-71. PMID: 10409281.
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      86. Gu DL, Gonzalez AM, Printz MA, Doukas J, Ying W, D'Andrea M, Hoganson DK, Curiel DT, Douglas JT, Sosnowski BA, Baird A, Aukerman SL, Pierce GF. Fibroblast growth factor 2 retargeted adenovirus has redirected cellular tropism: evidence for reduced toxicity and enhanced antitumor activity in mice. Cancer Res. 1999 Jun 01; 59(11):2608-14. PMID: 10363982.
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      87. Chandler LA, Sosnowski BA, Greenlees L, Aukerman SL, Baird A, Pierce GF. Prevalent expression of fibroblast growth factor (FGF) receptors and FGF2 in human tumor cell lines. Int J Cancer. 1999 May 05; 81(3):451-8. PMID: 10209961.
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      88. Larocca D, Kassner PD, Witte A, Ladner RC, Pierce GF, Baird A. Gene transfer to mammalian cells using genetically targeted filamentous bacteriophage. FASEB J. 1999 Apr; 13(6):727-34. PMID: 10094933.
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      89. Hoganson DK, Chandler LA, Fleurbaaij GA, Ying W, Black ME, Doukas J, Pierce GF, Baird A, Sosnowski BA. Targeted delivery of DNA encoding cytotoxic proteins through high-affinity fibroblast growth factor receptors. Hum Gene Ther. 1998 Nov 20; 9(17):2565-75. PMID: 9853523.
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      90. Larocca D, Witte A, Johnson W, Pierce GF, Baird A. Targeting bacteriophage to mammalian cell surface receptors for gene delivery. Hum Gene Ther. 1998 Nov 01; 9(16):2393-9. PMID: 9829538.
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      91. Dazert S, Kim D, Luo L, Aletsee C, Garfunkel S, Maciag T, Baird A, Ryan AF. Focal delivery of fibroblast growth factor-1 by transfected cells induces spiral ganglion neurite targeting in vitro. J Cell Physiol. 1998 Oct; 177(1):123-9. PMID: 9731752.
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      92. Chandler LA, Sosnowski BA, McDonald JR, Price JE, Aukerman SL, Baird A, Pierce GF, Houston LL. Targeting tumor cells via EGF receptors: selective toxicity of an HBEGF-toxin fusion protein. Int J Cancer. 1998 Sep 25; 78(1):106-11. PMID: 9724101.
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      93. Florkiewicz RZ, Anchin J, Baird A. The inhibition of fibroblast growth factor-2 export by cardenolides implies a novel function for the catalytic subunit of Na+,K+-ATPase. J Biol Chem. 1998 Jan 02; 273(1):544-51. PMID: 9417114.
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      94. Dazert S, Baird A, Ryan AF. Receptor-targeted delivery of an intracellular toxin to outer hair cells by fibroblast growth factor. Hear Res. 1998 Jan; 115(1-2):143-8. PMID: 9472743.
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      95. Fenton H, Finch PW, Rubin JS, Rosenberg JM, Taylor WG, Kuo-Leblanc V, Rodriguez-Wolf M, Baird A, Schipper HM, Stopa EG. Hepatocyte growth factor (HGF/SF) in Alzheimer's disease. Brain Res. 1998 Jan 01; 779(1-2):262-70. PMID: 9473690.
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      96. Ray J, Baird A, Gage FH. A 10-amino acid sequence of fibroblast growth factor 2 is sufficient for its mitogenic activity on neural progenitor cells. Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13):7047-52. PMID: 9192689; PMCID: PMC21282.
      97. Goldman CK, Rogers BE, Douglas JT, Sosnowski BA, Ying W, Siegal GP, Baird A, Campain JA, Curiel DT. Targeted gene delivery to Kaposi's sarcoma cells via the fibroblast growth factor receptor. Cancer Res. 1997 Apr 15; 57(8):1447-51. PMID: 9108444.
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      98. Jones EM, Baird A. Cell-surface ADP-ribosylation of fibroblast growth factor-2 by an arginine-specific ADP-ribosyltransferase. Biochem J. 1997 Apr 01; 323 ( Pt 1):173-7. PMID: 9173879; PMCID: PMC1218292.
      99. Sosnowski BA, Gonzalez AM, Chandler LA, Buechler YJ, Pierce GF, Baird A. Targeting DNA to cells with basic fibroblast growth factor (FGF2). J Biol Chem. 1996 Dec 27; 271(52):33647-53. PMID: 8969234.
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      100. de Iongh RU, Lovicu FJ, Hanneken A, Baird A, McAvoy JW. FGF receptor-1 (flg) expression is correlated with fibre differentiation during rat lens morphogenesis and growth. Dev Dyn. 1996 Aug; 206(4):412-26. PMID: 8853990.
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      101. Fuxe K, Tinner B, Zoli M, Pettersson RF, Baird A, Biagini G, Chadi G, Agnati LF. Computer-assisted mapping of basic fibroblast growth factor immunoreactive nerve cell populations in the rat brain. J Chem Neuroanat. 1996 Jul; 11(1):13-35. PMID: 8841886.
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      102. Low W, Dazert S, Baird A, Ryan AF. Basic fibroblast growth factor (FGF-2) protects rat cochlear hair cells in organotypical culture from aminoglycoside injury. J Cell Physiol. 1996 Jun; 167(3):443-50. PMID: 8655598.
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      103. Gonzalez AM, Hill DJ, Logan A, Maher PA, Baird A. Distribution of fibroblast growth factor (FGF)-2 and FGF receptor-1 messenger RNA expression and protein presence in the mid-trimester human fetus. Pediatr Res. 1996 Mar; 39(3):375-85. PMID: 8929854.
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      104. Gonzalez AM, Berry M, Maher PA, Logan A, Baird A. A comprehensive analysis of the distribution of FGF-2 and FGFR1 in the rat brain. Brain Res. 1995 Dec 01; 701(1-2):201-26. PMID: 8925285.
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      105. Boulle N, Jones EM, Auguste P, Baird A. Adenosine diphosphate ribosylation of fibroblast growth factor-2. Mol Endocrinol. 1995 Jun; 9(6):767-75. PMID: 8592522.
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      106. Feige JJ, Baird A. Crinopexy: extracellular regulation of growth factor action. Kidney Int Suppl. 1995 Jun; 49:S15-8. PMID: 7674586.
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      107. Luo L, Moore JK, Baird A, Ryan AF. Expression of acidic FGF mRNA in rat auditory brainstem during postnatal maturation. Brain Res Dev Brain Res. 1995 May 26; 86(1-2):24-34. PMID: 7544700.
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      108. Hanneken A, Baird A. Soluble forms of the high-affinity fibroblast growth factor receptor in human vitreous fluid. Invest Ophthalmol Vis Sci. 1995 May; 36(6):1192-6. PMID: 7730030.
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      109. Hanneken A, Frautschy S, Galasko D, Baird A. A fibroblast growth factor binding protein in human cerebral spinal fluid. Neuroreport. 1995 Apr 19; 6(6):886-8. PMID: 7612876.
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      110. Denton DA, Blair-West JR, McBurnie M, Weisinger RS, Logan A, Gonzales AM, Baird A. Central action of basic fibroblast growth factor on ingestive behaviour in mice. Physiol Behav. 1995 Apr; 57(4):747-52. PMID: 7777612.
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      111. Hanneken A, Maher PA, Baird A. High affinity immunoreactive FGF receptors in the extracellular matrix of vascular endothelial cells--implications for the modulation of FGF-2. J Cell Biol. 1995 Mar; 128(6):1221-8. PMID: 7896883; PMCID: PMC2120425.
      112. Ray J, Hogg J, Beutler AS, Takayama H, Baird A, Gage FH. Expression of biologically active basic fibroblast growth factor by genetically modified rat primary skin fibroblasts. J Neurochem. 1995 Feb; 64(2):503-13. PMID: 7830042.
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      113. Takayama H, Ray J, Raymon HK, Baird A, Hogg J, Fisher LJ, Gage FH. Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease. Nat Med. 1995 Jan; 1(1):53-8. PMID: 7584953.
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      114. Gonzalez AM, Carman LS, Ong M, Ray J, Gage FH, Shults CW, Baird A. Storage, metabolism, and processing of 125I-fibroblast growth factor-2 after intracerebral injection. Brain Res. 1994 Dec 05; 665(2):285-92. PMID: 7895064.
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      115. Logan A, Gonzalez AM, Hill DJ, Berry M, Gregson NA, Baird A. Coordinated pattern of expression and localization of insulin-like growth factor-II (IGF-II) and IGF-binding protein-2 in the adult rat brain. Endocrinology. 1994 Nov; 135(5):2255-64. PMID: 7525264.
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      116. Geller J, Sionit LR, Baird A, Kohls M, Connors KM, Hoffman RM. In vivo and in vitro effects of androgen on fibroblast growth factor-2 concentrations in the human prostate. Prostate. 1994 Oct; 25(4):206-9. PMID: 7521961.
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      117. Hanneken A, Ying W, Ling N, Baird A. Identification of soluble forms of the fibroblast growth factor receptor in blood. Proc Natl Acad Sci U S A. 1994 Sep 13; 91(19):9170-4. PMID: 8090787; PMCID: PMC44769.
      118. Baird A. Potential mechanisms regulating the extracellular activities of basic fibroblast growth factor (FGF-2). Mol Reprod Dev. 1994 Sep; 39(1):43-8. PMID: 7528026.
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      119. Ying W, Martineau D, Beitz J, Lappi DA, Baird A. Anti-B16-F10 melanoma activity of a basic fibroblast growth factor-saporin mitotoxin. Cancer. 1994 Aug 01; 74(3):848-53. PMID: 8039113.
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      120. Otonkoski T, Beattie GM, Rubin JS, Lopez AD, Baird A, Hayek A. Hepatocyte growth factor/scatter factor has insulinotropic activity in human fetal pancreatic cells. Diabetes. 1994 Jul; 43(7):947-53. PMID: 8013761.
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      121. Gonzalez AM, Logan A, Ying W, Lappi DA, Berry M, Baird A. Fibroblast growth factor in the hypothalamic-pituitary axis: differential expression of fibroblast growth factor-2 and a high affinity receptor. Endocrinology. 1994 May; 134(5):2289-97. PMID: 8156932.
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      122. Lappi DA, Ying W, Barthelemy I, Martineau D, Prieto I, Benatti L, Soria M, Baird A. Expression and activities of a recombinant basic fibroblast growth factor-saporin fusion protein. J Biol Chem. 1994 Apr 29; 269(17):12552-8. PMID: 8175664.
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      123. Koutnouyan HA, Baird A, Ryan AF. Acidic and basic FGF mRNA expression in the middle ear mucosa during experimental acute and chronic otitis media. Laryngoscope. 1994 Mar; 104(3 Pt 1):350-8. PMID: 7510359.
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      124. Tuszynski MH, Peterson DA, Ray J, Baird A, Nakahara Y, Gage FH. Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord. Exp Neurol. 1994 Mar; 126(1):1-14. PMID: 8157119.
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      125. Logan A, Berry M, Gonzalez AM, Frautschy SA, Sporn MB, Baird A. Effects of transforming growth factor beta 1 on scar production in the injured central nervous system of the rat. Eur J Neurosci. 1994 Mar 01; 6(3):355-63. PMID: 8019673.
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      126. Baird A. Fibroblast growth factors: activities and significance of non-neurotrophin neurotrophic growth factors. Curr Opin Neurobiol. 1994 Feb; 4(1):78-86. PMID: 8173328.
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      127. Casscells W, Lappi DA, Baird A. Molecular atherectomy for restenosis. Trends Cardiovasc Med. 1993 Nov-Dec; 3(6):235-43. PMID: 21244914; PMCID: PMC4524533.
      128. Vilgrain I, Gonzalez AM, Baird A. Phosphorylation of basic fibroblast growth factor (FGF-2) in the nuclei of SK-Hep-1 cells. FEBS Lett. 1993 Oct 04; 331(3):228-32. PMID: 8397111.
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      129. Luo L, Koutnouyan H, Baird A, Ryan AF. Acidic and basic FGF mRNA expression in the adult and developing rat cochlea. Hear Res. 1993 Sep; 69(1-2):182-93. PMID: 7693641.
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      130. Lappi DA, Matsunami R, Martineau D, Baird A. Reducing the heterogeneity of chemically conjugated targeted toxins: homogeneous basic FGF-saporin. Anal Biochem. 1993 Aug 01; 212(2):446-51. PMID: 8214586.
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      131. Fina M, Baird A, Ryan A. Direct application of basic fibroblast growth factor improves tympanic membrane perforation healing. Laryngoscope. 1993 Jul; 103(7):804-9. PMID: 8341107.
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      132. Baird A. Fibroblast growth factors: what's in a name? Endocrinology. 1993 Feb; 132(2):487-8. PMID: 8425469.
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      133. Ryan AF, Baird A. Growth factors during proliferation of the middle ear mucosa. Acta Otolaryngol. 1993 Jan; 113(1):68-74. PMID: 8442425.
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      134. Lappi DA, Martineau D, Sarmientos P, Garofano L, Aranda AP, Miyajima A, Kitamura T, Baird A. Characterization of a saporin mitotoxin specifically cytotoxic to cells bearing the granulocyte-macrophage colony-stimulating factor receptor. Growth Factors. 1993; 9(1):31-9. PMID: 8347350.
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      135. David T, Tassin J, Lappi DA, Baird A, Courtois Y. Biphasic effect of the mitotoxin bFGF-saporin on bovine lens epithelial cell growth: effect of cell density and extracellular matrix. J Cell Physiol. 1992 Dec; 153(3):483-90. PMID: 1447311.
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      136. Logan A, Frautschy SA, Gonzalez AM, Baird A. A time course for the focal elevation of synthesis of basic fibroblast growth factor and one of its high-affinity receptors (flg) following a localized cortical brain injury. J Neurosci. 1992 Oct; 12(10):3828-37. PMID: 1403086; PMCID: PMC4086626.
      137. Gonzalez AM, Buscaglia M, Fox R, Isacchi A, Sarmientos P, Farris J, Ong M, Martineau D, Lappi DA, Baird A. Basic fibroblast growth factor in Dupuytren's contracture. Am J Pathol. 1992 Sep; 141(3):661-71. PMID: 1325742; PMCID: PMC1886703.
      138. Yoshida K, Kakihana M, Chen LS, Ong M, Baird A, Gage FH. Cytokine regulation of nerve growth factor-mediated cholinergic neurotrophic activity synthesized by astrocytes and fibroblasts. J Neurochem. 1992 Sep; 59(3):919-31. PMID: 1494917.
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      139. Logan A, Frautschy SA, Gonzalez AM, Sporn MB, Baird A. Enhanced expression of transforming growth factor beta 1 in the rat brain after a localized cerebral injury. Brain Res. 1992 Aug 07; 587(2):216-25. PMID: 1525658; PMCID: PMC4310563.
      140. Speir E, Tanner V, Gonzalez AM, Farris J, Baird A, Casscells W. Acidic and basic fibroblast growth factors in adult rat heart myocytes. Localization, regulation in culture, and effects on DNA synthesis. Circ Res. 1992 Aug; 71(2):251-9. PMID: 1378359.
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      141. Schiff M, Gonzalez AM, Ong M, Baird A. Juvenile nasopharyngeal angiofibroma contain an angiogenic growth factor: basic FGF. Laryngoscope. 1992 Aug; 102(8):940-5. PMID: 1323004.
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      142. Casscells W, Lappi DA, Olwin BB, Wai C, Siegman M, Speir EH, Sasse J, Baird A. Elimination of smooth muscle cells in experimental restenosis: targeting of fibroblast growth factor receptors. Proc Natl Acad Sci U S A. 1992 Aug 01; 89(15):7159-63. PMID: 1323129; PMCID: PMC49665.
      143. Hanneken A, Baird A. Immunolocalization of basic fibroblast growth factor: dependence on antibody type and tissue fixation. Exp Eye Res. 1992 Jun; 54(6):1011-4. PMID: 1521575.
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      144. Alvarez JA, Baird A, Tatum A, Daucher J, Chorsky R, Gonzalez AM, Stopa EG. Localization of basic fibroblast growth factor and vascular endothelial growth factor in human glial neoplasms. Mod Pathol. 1992 May; 5(3):303-7. PMID: 1495934.
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      145. Lappi DA, Martineau D, Maher PA, Florkiewicz RZ, Buscaglia M, Gonzalez AM, Farris J, Hamer M, Fox R, Baird A. Basic fibroblast growth factor in cells derived from Dupuytren's contracture: synthesis, presence, and implications for treatment of the disease. J Hand Surg Am. 1992 Mar; 17(2):324-32. PMID: 1314273.
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      146. Beitz JG, Davol P, Clark JW, Kato J, Medina M, Frackelton AR, Lappi DA, Baird A, Calabresi P. Antitumor activity of basic fibroblast growth factor-saporin mitotoxin in vitro and in vivo. Cancer Res. 1992 Jan 01; 52(1):227-30. PMID: 1309225.
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      147. Brown MR, Vaughan J, Jimenez LL, Vale W, Baird A. Transforming growth factor-beta: role in mediating serum-induced endothelin production by vascular endothelial cells. Endocrinology. 1991 Nov; 129(5):2355-60. PMID: 1935770.
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      148. Klagsbrun M, Baird A. A dual receptor system is required for basic fibroblast growth factor activity. Cell. 1991 Oct 18; 67(2):229-31. PMID: 1655276.
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      149. Cuevas P, Gonzalez AM, Carceller F, Baird A. Vascular response to basic fibroblast growth factor when infused onto the normal adventitia or into the injured media of the rat carotid artery. Circ Res. 1991 Aug; 69(2):360-9. PMID: 1713534.
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      150. Frautschy SA, Walicke PA, Baird A. Localization of basic fibroblast growth factor and its mRNA after CNS injury. Brain Res. 1991 Jul 12; 553(2):291-9. PMID: 1933286; PMCID: PMC4352091.
      151. Beattie GM, Lappi DA, Baird A, Hayek A. Functional impact of attachment and purification in the short term culture of human pancreatic islets. J Clin Endocrinol Metab. 1991 Jul; 73(1):93-8. PMID: 2045476.
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      152. Vilgrain I, Baird A. Phosphorylation of basic fibroblast growth factor by a protein kinase associated with the outer surface of a target cell. Mol Endocrinol. 1991 Jul; 5(7):1003-12. PMID: 1658631.
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      153. Frautschy SA, Gonzalez AM, Martinez Murillo R, Carceller F, Cuevas P, Baird A. Expression of basic fibroblast growth factor and its receptor in the rat subfornical organ. Neuroendocrinology. 1991 Jul; 54(1):55-61. PMID: 1656299; PMCID: PMC4237606.
      154. Walicke PA, Baird A. Internalization and processing of basic fibroblast growth factor by neurons and astrocytes. J Neurosci. 1991 Jul; 11(7):2249-58. PMID: 1648607.
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      155. Baird A, Klagsbrun M. The fibroblast growth factor family. Cancer Cells. 1991 Jun; 3(6):239-43. PMID: 1911037.
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      156. Lappi DA, Maher PA, Martineau D, Baird A. The basic fibroblast growth factor-saporin mitotoxin acts through the basic fibroblast growth factor receptor. J Cell Physiol. 1991 Apr; 147(1):17-26. PMID: 1645359.
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      157. Emoto N, Ling N, Baird A. Growth factor-mediated regulation of aromatase activity in human skin fibroblasts. Proc Soc Exp Biol Med. 1991 Mar; 196(3):351-8. PMID: 1671798.
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      158. Shults CW, O'Connor DT, Baird A, Hill R, Goetz CG, Watts RL, Klawans HL, Carvey PM, Bakay RA, Gage FH. Clinical improvement in parkinsonian patients undergoing adrenal to caudate transplantation is not reflected by chromogranin A or basic fibroblast growth factor in ventricular fluid. Exp Neurol. 1991 Mar; 111(3):276-81. PMID: 1999231.
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      159. Feige JJ, Ling N, Baird A. Phosphorylation of basic fibroblast growth factor by purified protein kinase C and the identification of a cryptic site of phosphorylation. Biochem Biophys Res Commun. 1991 Feb 28; 175(1):31-6. PMID: 1900153.
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      160. Gonzalez AM, Buscaglia ML, Fuller J, Dahl R, Carman LS, Baird A. Local fate and distribution of locally infused basic FGF. The example of the rat brain and the Xenopus tail mesenchyme. Ann N Y Acad Sci. 1991; 638:416-9. PMID: 1785813.
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      161. Fina M, Bresnick S, Baird A, Ryan A. Improved healing of tympanic membrane perforations with basic fibroblast growth factor. Growth Factors. 1991; 5(4):265-72. PMID: 1777236.
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      162. Emoto N, Isozaki O, Arai M, Murakami H, Shizume K, Baird A, Tsushima T, Demura H. Identification and characterization of basic fibroblast growth factor in porcine thyroids. Endocrinology. 1991 Jan; 128(1):58-64. PMID: 1702706.
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      163. Gonzalez AM, Lappi DA, Buscaglia ML, Carman LS, Gage FH, Baird A. Basic FGF-SAP mitotoxin in the hippocampus. Specific lethal effect on cells expressing the basic FGF receptor. Ann N Y Acad Sci. 1991; 638:442-4. PMID: 1664696.
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      164. Feige JJ, Baird A. Growth factor regulation of adrenal cortex growth and function. Prog Growth Factor Res. 1991; 3(2):103-13. PMID: 1663405.
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      165. Kiefer MC, Baird A, Nguyen T, George-Nascimento C, Mason OB, Boley LJ, Valenzuela P, Barr PJ. Molecular cloning of a human basic fibroblast growth factor receptor cDNA and expression of a biologically active extracellular domain in a baculovirus system. Growth Factors. 1991; 5(2):115-27. PMID: 1662973.
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      166. Isik FF, Valentine HA, McDonald TO, Baird A, Gordon D. Localization of bFGF in human transplant coronary atherosclerosis. Ann N Y Acad Sci. 1991; 638:487-8. PMID: 1785825.
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      167. Logan A, Frautschy SA, Baird A. Basic fibroblast growth factor and central nervous system injury. Ann N Y Acad Sci. 1991; 638:474-6. PMID: 1785823; PMCID: PMC4086467.
      168. Shibata F, Baird A, Florkiewicz RZ. Functional characterization of the human basic fibroblast growth factor gene promoter. Growth Factors. 1991; 4(4):277-87. PMID: 1764264.
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      169. Feige JJ, Baird A. Phosphorylation and identification of phosphorylated forms of basic fibroblast growth factor. Methods Enzymol. 1991; 198:138-47. PMID: 1857215.
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      170. Vilgrain I, Baird A. Basic fibroblast growth factor is phosphorylated by an ecto-protein kinase associated with the surface of SK-Hep cells. Ann N Y Acad Sci. 1991; 638:445-8. PMID: 1664697.
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      171. Lindner V, Lappi DA, Baird A, Majack RA, Reidy MA. Role of basic fibroblast growth factor in vascular lesion formation. Circ Res. 1991 Jan; 68(1):106-13. PMID: 1984855.
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      172. Martineau D, Lappi DA, Amburn E, Baird A. Basic fibroblast growth factor-saporin mitotoxin. In vitro studies of its cell-killing activity and of substances that alter that activity. Ann N Y Acad Sci. 1991; 638:438-41. PMID: 1785818.
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      173. Prieto I, Lappi DA, Ong M, Matsunami R, Benatti L, Villares R, Soria M, Sarmientos P, Baird A. Expression and characterization of a basic fibroblast growth factor-saporin fusion protein in Escherichia coli. Ann N Y Acad Sci. 1991; 638:434-7. PMID: 1785817.
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      174. Buscaglia ML, Ong M, Fuller J, Gonzalez AM, Baird A. Inhibition of pregnancy in the passively and actively immunized mammals rabbit, rat, and mouse. Ann N Y Acad Sci. 1991; 638:494-6. PMID: 1785828.
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      175. Florkiewicz RZ, Shibata F, Barankiewicz T, Baird A, Gonzalez AM, Florkiewicz E, Shah N. Basic fibroblast growth factor gene expression. Ann N Y Acad Sci. 1991; 638:109-26. PMID: 1785797.
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      176. Florkiewicz RZ, Baird A, Gonzalez AM. Multiple forms of bFGF: differential nuclear and cell surface localization. Growth Factors. 1991; 4(4):265-75. PMID: 1764263.
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      177. Brown MR, Vaughan J, Walsh J, Jimenez L, Hexum TD, Baird A, Vale W. Endothelin releasing activity in calf serum and porcine follicular fluid. Biochem Biophys Res Commun. 1990 Dec 31; 173(3):807-15. PMID: 2268344.
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      178. Baird A, Florkiewicz RZ, Maher PA, Kaner RJ, Hajjar DP. Mediation of virion penetration into vascular cells by association of basic fibroblast growth factor with herpes simplex virus type 1. Nature. 1990 Nov 22; 348(6299):344-6. PMID: 2174511.
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      179. Stopa EG, Gonzalez AM, Chorsky R, Corona RJ, Alvarez J, Bird ED, Baird A. Basic fibroblast growth factor in Alzheimer's disease. Biochem Biophys Res Commun. 1990 Sep 14; 171(2):690-6. PMID: 2403357.
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      180. Beattie GM, Lappi DA, Baird A, Hayek A. Selective elimination of fibroblasts from pancreatic islet monolayers by basic fibroblast growth factor-saporin mitotoxin. Diabetes. 1990 Aug; 39(8):1002-5. PMID: 2165003.
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      181. Kaner RJ, Baird A, Mansukhani A, Basilico C, Summers BD, Florkiewicz RZ, Hajjar DP. Fibroblast growth factor receptor is a portal of cellular entry for herpes simplex virus type 1. Science. 1990 Jun 15; 248(4961):1410-3. PMID: 2162560.
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      182. Gonzalez AM, Buscaglia M, Ong M, Baird A. Distribution of basic fibroblast growth factor in the 18-day rat fetus: localization in the basement membranes of diverse tissues. J Cell Biol. 1990 Mar; 110(3):753-65. PMID: 1689733; PMCID: PMC2116039.
      183. Hexum TD, Hoeger C, Rivier JE, Baird A, Brown MR. Characterization of endothelin secretion by vascular endothelial cells. Biochem Biophys Res Commun. 1990 Feb 28; 167(1):294-300. PMID: 2178609.
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      184. Lappi DA, Baird A. Mitotoxins: growth factor-targeted cytotoxic molecules. Prog Growth Factor Res. 1990; 2(4):223-36. PMID: 2133290.
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      185. Feige JJ, Bradley JD, Fryburg K, Farris J, Cousens LC, Barr PJ, Baird A. Differential effects of heparin, fibronectin, and laminin on the phosphorylation of basic fibroblast growth factor by protein kinase C and the catalytic subunit of protein kinase A. J Cell Biol. 1989 Dec; 109(6 Pt 1):3105-14. PMID: 2592418; PMCID: PMC2115963.
      186. Feige JJ, Baird A. Basic fibroblast growth factor is a substrate for protein phosphorylation and is phosphorylated by capillary endothelial cells in culture. Proc Natl Acad Sci U S A. 1989 May; 86(9):3174-8. PMID: 2541433; PMCID: PMC287089.
      187. Lappi DA, Martineau D, Baird A. Biological and chemical characterization of basic FGF-saporin mitotoxin. Biochem Biophys Res Commun. 1989 Apr 28; 160(2):917-23. PMID: 2541718.
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      188. Baird A, Walicke PA. Fibroblast growth factors. Br Med Bull. 1989 Apr; 45(2):438-52. PMID: 2480829.
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      189. Wehrenberg WB, Baird A, Klepper R, Mormede P, Ling N. Interactions between growth hormone-releasing hormone and glucocorticoids in male rats. Regul Pept. 1989 Apr; 25(1):147-55. PMID: 2497499.
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      190. Walicke PA, Feige JJ, Baird A. Characterization of the neuronal receptor for basic fibroblast growth factor and comparison to receptors on mesenchymal cells. J Biol Chem. 1989 Mar 05; 264(7):4120-6. PMID: 2537305.
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      191. Emoto N, Gonzalez AM, Walicke PA, Wada E, Simmons DM, Shimasaki S, Baird A. Basic fibroblast growth factor (FGF) in the central nervous system: identification of specific loci of basic FGF expression in the rat brain. Growth Factors. 1989; 2(1):21-9. PMID: 2635054.
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      192. Fauser BC, Baird A, Hsueh AJ. Fibroblast growth factor inhibits luteinizing hormone-stimulated androgen production by cultured rat testicular cells. Endocrinology. 1988 Dec; 123(6):2935-41. PMID: 2848690.
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      193. Shimasaki S, Emoto N, Koba A, Mercado M, Shibata F, Cooksey K, Baird A, Ling N. Complementary DNA cloning and sequencing of rat ovarian basic fibroblast growth factor and tissue distribution study of its mRNA. Biochem Biophys Res Commun. 1988 Nov 30; 157(1):256-63. PMID: 3196337.
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      194. Cuevas P, Burgos J, Baird A. Basic fibroblast growth factor (FGF) promotes cartilage repair in vivo. Biochem Biophys Res Commun. 1988 Oct 31; 156(2):611-8. PMID: 3190672.
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      195. Feige JJ, Baird A. Glycosylation of the basic fibroblast growth factor receptor. The contribution of carbohydrate to receptor function. J Biol Chem. 1988 Oct 05; 263(28):14023-9. PMID: 2844752.
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      196. Emoto N, Baird A. The effect of tumor necrosis factor/cachectin on follicle-stimulating hormone-induced aromatase activity in cultured rat granulosa cells. Biochem Biophys Res Commun. 1988 Jun 16; 153(2):792-8. PMID: 3132919.
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      197. Walicke PA, Baird A. Neurotrophic effects of basic and acidic fibroblast growth factors are not mediated through glial cells. Brain Res. 1988 May 01; 468(1):71-9. PMID: 3132309.
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      198. Baird A, Schubert D, Ling N, Guillemin R. Receptor- and heparin-binding domains of basic fibroblast growth factor. Proc Natl Acad Sci U S A. 1988 Apr; 85(7):2324-8. PMID: 2832850; PMCID: PMC279984.
      199. Zeytin FN, Rusk SF, Baird A, Raymond V, Leff SE, Haaparanta T, Mandell AJ. Induction of c-fos, calcitonin gene expression, and acidic fibroblast growth factor production in a multipeptide-secreting neuroendocrine cell line. Endocrinology. 1988 Mar; 122(3):1114-20. PMID: 2893727.
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      200. Walicke PA, Baird A. Trophic effects of fibroblast growth factor on neural tissue. Prog Brain Res. 1988; 78:333-8. PMID: 3073416.
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      201. Hayek A, Culler FL, Beattie GM, Lopez AD, Cuevas P, Baird A. An in vivo model for study of the angiogenic effects of basic fibroblast growth factor. Biochem Biophys Res Commun. 1987 Sep 15; 147(2):876-80. PMID: 2443140.
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      202. Hotta M, Baird A. The inhibition of low density lipoprotein metabolism by transforming growth factor-beta mediates its effects on steroidogenesis in bovine adrenocortical cells in vitro. Endocrinology. 1987 Jul; 121(1):150-9. PMID: 3036466.
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      203. Schubert D, Ling N, Baird A. Multiple influences of a heparin-binding growth factor on neuronal development. J Cell Biol. 1987 Mar; 104(3):635-43. PMID: 3818795; PMCID: PMC2114536.
      204. Ueno N, Baird A, Esch F, Ling N, Guillemin R. Isolation and partial characterization of basic fibroblast growth factor from bovine testis. Mol Cell Endocrinol. 1987 Feb; 49(2-3):189-94. PMID: 3556754.
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      205. Baird A, Ling N. Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells in vitro: implications for a role of heparinase-like enzymes in the neovascular response. Biochem Biophys Res Commun. 1987 Jan 30; 142(2):428-35. PMID: 2434094.
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      206. Baird A, Ueno N, Esch F, Ling N. Distribution of fibroblast growth factors (FGFs) in tissues and structure-function studies with synthetic fragments of basic FGF. J Cell Physiol Suppl. 1987; Suppl 5:101-6. PMID: 3479434.
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      207. Halaban R, Ghosh S, Baird A. bFGF is the putative natural growth factor for human melanocytes. In Vitro Cell Dev Biol. 1987 Jan; 23(1):47-52. PMID: 3027025.
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      208. Baird A, Hsueh AJ. Fibroblast growth factor as an intraovarian hormone: differential regulation of steroidogenesis by an angiogenic factor. Regul Pept. 1986 Dec 30; 16(3-4):243-50. PMID: 3104999.
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      209. Ueno N, Baird A, Esch F, Shimasaki S, Ling N, Guillemin R. Purification and partial characterization of a mitogenic factor from bovine liver: structural homology with basic fibroblast growth factor. Regul Pept. 1986 Dec 22; 16(2):135-45. PMID: 3809608.
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      210. Montesano R, Vassalli JD, Baird A, Guillemin R, Orci L. Basic fibroblast growth factor induces angiogenesis in vitro. Proc Natl Acad Sci U S A. 1986 Oct; 83(19):7297-301. PMID: 2429303; PMCID: PMC386703.
      211. Hotta M, Baird A. Differential effects of transforming growth factor type beta on the growth and function of adrenocortical cells in vitro. Proc Natl Acad Sci U S A. 1986 Oct; 83(20):7795-9. PMID: 3020557; PMCID: PMC386808.
      212. Ueno N, Baird A, Esch F, Ling N, Guillemin R. Isolation of an amino terminal extended form of basic fibroblast growth factor. Biochem Biophys Res Commun. 1986 Jul 31; 138(2):580-8. PMID: 3741423.
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      213. Baird A, Durkin T. Inhibition of endothelial cell proliferation by type beta-transforming growth factor: interactions with acidic and basic fibroblast growth factors. Biochem Biophys Res Commun. 1986 Jul 16; 138(1):476-82. PMID: 3461784.
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      214. Walicke P, Cowan WM, Ueno N, Baird A, Guillemin R. Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension. Proc Natl Acad Sci U S A. 1986 May; 83(9):3012-6. PMID: 3458259; PMCID: PMC323437.
      215. Ying SY, Becker A, Baird A, Ling N, Ueno N, Esch F, Guillemin R. Type beta transforming growth factor (TGF-beta) is a potent stimulator of the basal secretion of follicle stimulating hormone (FSH) in a pituitary monolayer system. Biochem Biophys Res Commun. 1986 Mar 28; 135(3):950-6. PMID: 3083816.
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      216. Baird A, Wehrenberg WB, Ling N. Relative potencies of human, rat, bovine/caprine, porcine and ovine hypothalamic growth hormone-releasing factors to release growth hormone by the rat anterior pituitary in vitro. Neuroendocrinology. 1986; 42(4):273-6. PMID: 3083281.
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      217. Bloch B, Baird A, Ling N, Guillemin R. Immunohistochemical evidence that growth hormone-releasing factor (GRF) neurons contain an amidated peptide derived from cleavage of the carboxyl-terminal end of the GRF precursor. Endocrinology. 1986 Jan; 118(1):156-62. PMID: 3079700.
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      218. Wehrenberg WB, Esch F, Baird A, Ying SY, Bölen P, Ling N. Growth hormone-releasing factor: a new chapter in neuroendocrinology. Horm Res. 1986; 24(2-3):82-90. PMID: 2875926.
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      219. Baird A, Esch F, Mormède P, Ueno N, Ling N, Böhlen P, Ying SY, Wehrenberg WB, Guillemin R. Molecular characterization of fibroblast growth factor: distribution and biological activities in various tissues. Recent Prog Horm Res. 1986; 42:143-205. PMID: 3526451.
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      220. Baird A, Mormède P, Böhlen P. Immunoreactive fibroblast growth factor (FGF) in a transplantable chondrosarcoma: inhibition of tumor growth by antibodies to FGF. J Cell Biochem. 1986; 30(1):79-85. PMID: 3958062.
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      221. Gospodarowicz D, Baird A, Cheng J, Lui GM, Esch F, Bohlen P. Isolation of fibroblast growth factor from bovine adrenal gland: physicochemical and biological characterization. Endocrinology. 1986 Jan; 118(1):82-90. PMID: 3940857.
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      222. Baird A, Esch F, Gospodarowicz D, Guillemin R. Retina- and eye-derived endothelial cell growth factors: partial molecular characterization and identity with acidic and basic fibroblast growth factors. Biochemistry. 1985 Dec 31; 24(27):7855-60. PMID: 3912009.
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      223. Esch F, Ueno N, Baird A, Hill F, Denoroy L, Ling N, Gospodarowicz D, Guillemin R. Primary structure of bovine brain acidic fibroblast growth factor (FGF). Biochem Biophys Res Commun. 1985 Dec 17; 133(2):554-62. PMID: 4084288.
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      224. Gospodarowicz D, Cheng J, Lui GM, Baird A, Esch F, Bohlen P. Corpus luteum angiogenic factor is related to fibroblast growth factor. Endocrinology. 1985 Dec; 117(6):2383-91. PMID: 4065037.
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      225. Baird A, Esch F, Böhlen P, Ling N, Gospodarowicz D. Isolation and partial characterization of an endothelial cell growth factor from the bovine kidney: homology with basic fibroblast growth factor. Regul Pept. 1985 Nov 07; 12(3):201-13. PMID: 4081126.
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      226. Esch F, Baird A, Ling N, Ueno N, Hill F, Denoroy L, Klepper R, Gospodarowicz D, Böhlen P, Guillemin R. Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc Natl Acad Sci U S A. 1985 Oct; 82(19):6507-11. PMID: 3863109; PMCID: PMC390746.
      227. Baird A, Wehrenberg WB, Böhlen P, Ling N. Immunoreactive and biologically active growth hormone-releasing factor in the rat placenta. Endocrinology. 1985 Oct; 117(4):1598-601. PMID: 3928335.
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      228. Baird A, Culler F, Jones KL, Guillemin R. Angiogenic factor in human ocular fluid. Lancet. 1985 Sep 07; 2(8454):563. PMID: 2412079.
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      229. Böhlen P, Esch F, Baird A, Gospodarowicz D. Acidic fibroblast growth factor (FGF) from bovine brain: amino-terminal sequence and comparison with basic FGF. EMBO J. 1985 Aug; 4(8):1951-6. PMID: 4065099; PMCID: PMC554446.
      230. Baird A, Mormède P, Ying SY, Wehrenberg WB, Ueno N, Ling N, Guillemin R. A nonmitogenic pituitary function of fibroblast growth factor: regulation of thyrotropin and prolactin secretion. Proc Natl Acad Sci U S A. 1985 Aug; 82(16):5545-9. PMID: 3927303; PMCID: PMC391159.
      231. Böhlen P, Esch F, Baird A, Jones KL, Gospodarowicz D. Human brain fibroblast growth factor. Isolation and partial chemical characterization. FEBS Lett. 1985 Jun 03; 185(1):177-81. PMID: 3996594.
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      232. Gospodarowicz D, Cheng J, Lui GM, Fujii DK, Baird A, Böhlen P. Fibroblast growth factor in the human placenta. Biochem Biophys Res Commun. 1985 Apr 30; 128(2):554-62. PMID: 3994712.
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      233. Baird A, Böhlen P, Ling N, Guillemin R. Radioimmunoassay for fibroblast growth factor (FGF): release by the bovine anterior pituitary in vitro. Regul Pept. 1985 Apr; 10(4):309-17. PMID: 4039829.
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      234. Reyl-Desmars F, Baird A, Zeytin FN. GRF is a highly potent activator of adenylate cyclase in the normal human, bovine and rat pituitary: interaction with somatostatin. Biochem Biophys Res Commun. 1985 Mar 29; 127(3):977-85. PMID: 2859017.
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      235. Wehrenberg WB, Baird A, Ying SY, Ling N. The effects of testosterone and estrogen on the pituitary growth hormone response to growth hormone-releasing factor. Biol Reprod. 1985 Mar; 32(2):369-75. PMID: 3921073.
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      236. Baird A, Mormède P, Böhlen P. Immunoreactive fibroblast growth factor in cells of peritoneal exudate suggests its identity with macrophage-derived growth factor. Biochem Biophys Res Commun. 1985 Jan 16; 126(1):358-64. PMID: 3970698.
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      237. Ling N, Zeytin F, Böhlen P, Esch F, Brazeau P, Wehrenberg WB, Baird A, Guillemin R. Growth hormone releasing factors. Annu Rev Biochem. 1985; 54:403-23. PMID: 2992358.
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      238. Benoit R, Bohlen P, Ling N, Esch F, Baird A, Ying SY, Wehrenberg WB, Guillemin R, Morrison JH, Bakhit C. Somatostatin-28 [1-12]-like peptides. Adv Exp Med Biol. 1985; 188:89-107. PMID: 2863951.
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      239. Wehrenberg WB, Baird A, Zeytin F, Esch F, Böhlen P, Ling N, Ying SY, Guillemin R. Physiological studies with somatocrinin, a growth hormone-releasing factor. Annu Rev Pharmacol Toxicol. 1985; 25:463-83. PMID: 2860847.
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      240. Kudo T, Baird A. Inhibition of aldosterone production in the adrenal glomerulosa by atrial natriuretic factor. Nature. 1984 Dec 20-1985 Jan 2; 312(5996):756-7. PMID: 6096716.
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      241. Baird A, Wehrenberg WB, Ling N. Ontogeny of the response to growth hormone-releasing factor. Regul Pept. 1984 Dec; 10(1):23-8. PMID: 6442442.
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      242. Gospodarowicz D, Cheng J, Lui GM, Baird A, Böhlent P. Isolation of brain fibroblast growth factor by heparin-Sepharose affinity chromatography: identity with pituitary fibroblast growth factor. Proc Natl Acad Sci U S A. 1984 Nov; 81(22):6963-7. PMID: 6594674; PMCID: PMC392056.
      243. Ling N, Baird A, Wehrenberg WB, Ueno N, Munegumi T, Brazeau P. Synthesis and in vitro bioactivity of C-terminal deleted analogs of human growth hormone-releasing factor. Biochem Biophys Res Commun. 1984 Sep 17; 123(2):854-61. PMID: 6435620.
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      244. Böhlen P, Baird A, Esch F, Ling N, Gospodarowicz D. Isolation and partial molecular characterization of pituitary fibroblast growth factor. Proc Natl Acad Sci U S A. 1984 Sep; 81(17):5364-8. PMID: 6591194; PMCID: PMC391704.
      245. Esch F, Ling N, Bohlen P, Baird A, Benoit R, Guillemin R. Isolation and characterization of the bovine hypothalamic corticotropin-releasing factor. Biochem Biophys Res Commun. 1984 Aug 16; 122(3):899-905. PMID: 6332625.
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      246. Ling N, Esch F, Böhlen P, Baird A, Guillemin R. Isolation and characterization of caprine corticotropin-releasing factor. Biochem Biophys Res Commun. 1984 Aug 16; 122(3):1218-24. PMID: 6332624.
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      247. Ling N, Baird A, Wehrenberg WB, Ueno N, Munegumi T, Chiang TC, Regno M, Brazeau P. Synthesis and in vitro bioactivity of human growth hormone-releasing factor analogs substituted at position-1. Biochem Biophys Res Commun. 1984 Jul 18; 122(1):304-10. PMID: 6430292.
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      248. Bloch B, Milner RJ, Baird A, Gubler U, Reymond C, Bohlen P, le Guellec D, Bloom FE. Detection of the messenger RNA coding for preproenkephalin A in bovine adrenal by in situ hybridization. Regul Pept. 1984 Jul; 8(4):345-54. PMID: 6548571.
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      249. Wehrenberg WB, Baird A, Ying SY, Rivier C, Ling N, Guillemin R. Multiple stimulation of the adenohypophysis by combinations of hypothalamic releasing factors. Endocrinology. 1984 Jun; 114(6):1995-2001. PMID: 6327231.
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      250. Baird A, Klepper R, Ling N. In vitro and in vivo evidence that the C-terminus of preproenkephalin-A circulates as an 8500-dalton molecule. Proc Soc Exp Biol Med. 1984 Mar; 175(3):304-8. PMID: 6546448.
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      251. Guillemin R, Brazeau P, Böhlen P, Esch F, Ling N, Wehrenberg WB, Bloch B, Mougin C, Zeytin F, Baird A. Somatocrinin, the growth hormone releasing factor. Recent Prog Horm Res. 1984; 40:233-99. PMID: 6148773.
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      252. Kan KW, Baird A, Solomon S. Gestational changes in the metabolism of progesterone by the fetal calf adrenal. Endocrinology. 1983 Sep; 113(3):1077-80. PMID: 6872950.
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      253. Wehrenberg WB, Baird A, Ling N. Potent interaction between glucocorticoids and growth hormone-releasing factor in vivo. Science. 1983 Aug 05; 221(4610):556-8. PMID: 6408735.
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      254. Baird A, Kan KW, Solomon S. Role of pro-opiomelanocortin-derived peptides in the regulation of steroid production by human fetal adrenal cells in culture. J Endocrinol. 1983 Jun; 97(3):357-67. PMID: 6306129.
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      255. Wehrenberg WB, Benoit R, Baird A, Guillemin R. Inhibitory effects of cysteamine on neuroendocrine function. Regul Pept. 1983 May; 6(2):137-45. PMID: 6410461.
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      256. Baird A, Kan KW, Solomon S. Androstenedione-mediated inhibition of 11 beta-hydroxylation in monolayer cell cultures of fetal calf adrenals. J Steroid Biochem. 1983 May; 18(5):581-4. PMID: 6602249.
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      257. Bloch B, Baird A, Ling N, Benoit R, Guillemin R. Immunohistochemical evidence that brain enkephalins arise from a precursor similar to adrenal preproenkephalin. Brain Res. 1983 Mar 21; 263(2):251-7. PMID: 6340794.
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      258. Wehrenberg WB, Ling N, Brazeau P, Esch F, Böhlen P, Baird A, Ying S, Guillemin R. Somatocrinin, growth hormone releasing factor, stimulates secretion of growth hormone in anesthetized rats. Biochem Biophys Res Commun. 1982 Nov 30; 109(2):382-7. PMID: 6817757.
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      259. Baird A, Wehrenberg WB, Shibasaki T, Benoit R, Chong-Li Z, Esch F, Ling N. Ovine corticotropin-releasing factor stimulates the concomitant secretion of corticotropin, beta-lipotropin, beta-endorphin and gamma-melanotropin by the bovine adenohypophysis in vitro. Biochem Biophys Res Commun. 1982 Oct 15; 108(3):959-64. PMID: 6295379.
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      260. Brubaker PL, Baird A, Bennett HP, Browne CA, Solomon S. Corticotropic peptides in the human fetal pituitary. Endocrinology. 1982 Oct; 111(4):1150-5. PMID: 6288348.
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      261. Baird A, Ling N, Böhlen P, Benoit R, Klepper R, Guillemin R. Molecular forms of the putative enkephalin precursor BAM-12P in bovine adrenal, pituitary, and hypothalamus. Proc Natl Acad Sci U S A. 1982 Mar; 79(6):2023-5. PMID: 6952250; PMCID: PMC346114.
      262. Böhlen P, Esch F, Shibasaki T, Baird A, Ling N, Guillemin R. Isolation and characterization of a gamma 1-melanotropin-like peptide from bovine neurointermediate pituitary. FEBS Lett. 1981 Jun 01; 128(1):67-70. PMID: 7274457.
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      263. Brubaker PL, Bennett HP, Baird A, Solomon S. Isolation of ACTH1-39,ACTH1-38 and CLIP from the calf anterior pituitary. Biochem Biophys Res Commun. 1980 Oct 16; 96(3):1441-8. PMID: 6254534.
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      264. Baird A, Brisson G, Kan KW, Duguid WC, Solomon S. Control of steroid synthesis in human fetal adrenals in monolayer culture. Can J Biochem. 1978 Jun; 56(6):577-84. PMID: 208729.
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      265. Kan KW, Baird A, Seidah NG, Lis M, Chrétien M, Ling N, Guillemin R, Solomon S. Effects of peptides of pituitary origin on the formation of C21 steroid by fetal calf adrenal cells in culture. Biochem Biophys Res Commun. 1977 Nov 21; 79(2):553-60. PMID: 201254; PMCID: PMC4524514.