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Arwa Kurabi

Title(s)Associate Project Scientist, Surgery
SchoolHealth Sciences
Phone858-534-4594
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    Collapse Research 
    Collapse Research Activities and Funding
    Establishment of an animal model of human-specific responses to middle ear infection.
    NIH/NIDCD R03DC014801Apr 5, 2016 - Mar 31, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lee J, Leichtle A, Zuckerman E, Pak K, Spriggs M, Wasserman SI, Kurabi A. NOD1/NOD2-mediated recognition of non-typeable Haemophilus influenzae activates innate immunity during otitis media. Innate Immun. 2019 Aug 31; 1753425919872266. PMID: 31474163.
      View in: PubMed
    2. Lim HW, Pak K, Kurabi A, Ryan AF. Lack of the hyaluronan receptor CD44 affects the course of bacterial otitis media and reduces leukocyte recruitment to the middle ear. BMC Immunol. 2019 Jun 21; 20(1):20. PMID: 31226944.
      View in: PubMed
    3. Kurabi A, Schaerer D, Noack V, Bernhardt M, Pak K, Alexander T, Husseman J, Nguyen Q, Harris JP, Ryan AF. Active Transport of Peptides Across the Intact Human Tympanic Membrane. Sci Rep. 2018 Aug 07; 8(1):11815. PMID: 30087425.
      View in: PubMed
    4. Lim HW, Pak K, Ryan AF, Kurabi A. Screening Mammalian Cochlear Hair Cells to Identify Critical Processes in Aminoglycoside-Mediated Damage. Front Cell Neurosci. 2018; 12:179. PMID: 30013464.
      View in: PubMed
    5. Hur DG, Kurabi A, Ryan AF. Screening antioxidants for the protection of cochlear sensory cells. Neural Regen Res. 2018 Jan; 13(1):62-64. PMID: 29451206.
      View in: PubMed
    6. Ryals M, Pak K, Jalota R, Kurabi A, Ryan AF. A kinase inhibitor library screen identifies novel enzymes involved in ototoxic damage to the murine organ of Corti. PLoS One. 2017; 12(10):e0186001. PMID: 29049311.
      View in: PubMed
    7. Deniffel D, Nuyen B, Pak K, Suzukawa K, Hung J, Kurabi A, Wasserman SI, Ryan AF. Otitis Media and Nasopharyngeal Colonization in ccl3-/- Mice. Infect Immun. 2017 11; 85(11). PMID: 28847849.
      View in: PubMed
    8. Noack V, Pak K, Jalota R, Kurabi A, Ryan AF. An Antioxidant Screen Identifies Candidates for Protection of Cochlear Hair Cells from Gentamicin Toxicity. Front Cell Neurosci. 2017; 11:242. PMID: 28867994.
      View in: PubMed
    9. Kurabi A, Schaerer D, Chang L, Pak K, Ryan AF. Optimisation of peptides that actively cross the tympanic membrane by random amino acid extension: a phage display study. J Drug Target. 2018 02; 26(2):127-134. PMID: 28658990.
      View in: PubMed
    10. Preciado D, Granath A, Lin J, Val S, Kurabi A, Johnston N, Vijayasekaran S, Valdez T, Depireux D, Hermansson A. Panel 8: Report on Recent Advances in Molecular and Cellular Biochemistry. Otolaryngol Head Neck Surg. 2017 04; 156(4_suppl):S106-S113. PMID: 28372528.
      View in: PubMed
    11. Kyd JM, Hotomi M, Kono M, Kurabi A, Pichichero M, Ryan A, Swords WE, Thornton R. Panel 5: Immunology. Otolaryngol Head Neck Surg. 2017 04; 156(4_suppl):S63-S75. PMID: 28372530.
      View in: PubMed
    12. Kurabi A, Beasley KA, Chang L, McCann J, Pak K, Ryan AF. Peptides actively transported across the tympanic membrane: Functional and structural properties. PLoS One. 2017; 12(2):e0172158. PMID: 28234923.
      View in: PubMed
    13. Kurabi A, Keithley EM, Housley GD, Ryan AF, Wong AC. Cellular mechanisms of noise-induced hearing loss. Hear Res. 2017 06; 349:129-137. PMID: 27916698.
      View in: PubMed
    14. Cho CG, Pak K, Webster N, Kurabi A, Ryan AF. Both canonical and non-canonical NF-?B activation contribute to the proliferative response of the middle ear mucosa during bacterial infection. Innate Immun. 2016 11; 22(8):626-634. PMID: 27655045.
      View in: PubMed
    15. Kurabi A, Pak KK, Bernhardt M, Baird A, Ryan AF. Discovery of a Biological Mechanism of Active Transport through the Tympanic Membrane to the Middle Ear. Sci Rep. 2016 Mar 07; 6:22663. PMID: 26946957.
      View in: PubMed
    16. Kurabi A, Pak K, Ryan AF, Wasserman SI. Innate Immunity: Orchestrating Inflammation and Resolution of Otitis Media. Curr Allergy Asthma Rep. 2016 Jan; 16(1):6. PMID: 26732809.
      View in: PubMed
    17. Podvin S, Dang X, Meads M, Kurabi A, Costantini T, Eliceiri BP, Baird A, Coimbra R. Esophageal cancer-related gene-4 (ECRG4) interactions with the innate immunity receptor complex. Inflamm Res. 2015 Feb; 64(2):107-18. PMID: 25511108.
      View in: PubMed
    18. Suzukawa K, Tomlin J, Pak K, Chavez E, Kurabi A, Baird A, Wasserman SI, Ryan AF. A mouse model of otitis media identifies HB-EGF as a mediator of inflammation-induced mucosal proliferation. PLoS One. 2014; 9(7):e102739. PMID: 25033458.
      View in: PubMed
    19. Kurabi A, Lee J, Wong C, Pak K, Hoffman HM, Ryan AF, Wasserman SI. The inflammasome adaptor ASC contributes to multiple innate immune processes in the resolution of otitis media. Innate Immun. 2015 Feb; 21(2):203-14. PMID: 24652041.
      View in: PubMed
    20. Baird A, Lee J, Podvin S, Kurabi A, Dang X, Coimbra R, Costantini T, Bansal V, Eliceiri BP. Esophageal cancer-related gene 4 at the interface of injury, inflammation, infection, and malignancy. Gastrointest Cancer. 2014; 2014(4):131-142. PMID: 25580077.
      View in: PubMed
    21. Smirnova E, Shanbhag R, Kurabi A, Mobli M, Kwan JJ, Donaldson LW. Solution structure and peptide binding of the PTB domain from the AIDA1 postsynaptic signaling scaffolding protein. PLoS One. 2013; 8(6):e65605. PMID: 23799029.
      View in: PubMed
    22. Kurabi A, Pak K, Dang X, Coimbra R, Eliceiri BP, Ryan AF, Baird A. Ecrg4 attenuates the inflammatory proliferative response of mucosal epithelial cells to infection. PLoS One. 2013; 8(4):e61394. PMID: 23626679.
      View in: PubMed
    23. Podvin S, Gonzalez AM, Miller MC, Dang X, Botfield H, Donahue JE, Kurabi A, Boissaud-Cooke M, Rossi R, Leadbeater WE, Johanson CE, Coimbra R, Stopa EG, Eliceiri BP, Baird A. Esophageal cancer related gene-4 is a choroid plexus-derived injury response gene: evidence for a biphasic response in early and late brain injury. PLoS One. 2011; 6(9):e24609. PMID: 21935431.
      View in: PubMed
    24. Shanbhag R, Kurabi A, Kwan JJ, Donaldson LW. Solution structure of the carboxy-terminal Tudor domain from human Coilin. FEBS Lett. 2010 Oct 22; 584(20):4351-6. PMID: 20875822.
      View in: PubMed
    25. Kurabi A, Brener S, Mobli M, Kwan JJ, Donaldson LW. A nuclear localization signal at the SAM-SAM domain interface of AIDA-1 suggests a requirement for domain uncoupling prior to nuclear import. J Mol Biol. 2009 Oct 09; 392(5):1168-77. PMID: 19666031.
      View in: PubMed
    26. Tu M, Zhang X, Kurabi A, Gilkes N, Mabee W, Saddler J. Immobilization of beta-glucosidase on Eupergit C for lignocellulose hydrolysis. Biotechnol Lett. 2006 Feb; 28(3):151-6. PMID: 16489491.
      View in: PubMed
    27. Berlin A, Gilkes N, Kurabi A, Bura R, Tu M, Kilburn D, Saddler J. Weak lignin-binding enzymes: a novel approach to improve activity of cellulases for hydrolysis of lignocellulosics. Appl Biochem Biotechnol. 2005; 121-124:163-70. PMID: 15917596.
      View in: PubMed
    28. Kurabi A, Berlin A, Gilkes N, Kilburn D, Bura R, Robinson J, Markov A, Skomarovsky A, Gusakov A, Okunev O, Sinitsyn A, Gregg D, Xie D, Saddler J. Enzymatic hydrolysis of steam-exploded and ethanol organosolv-pretreated Douglas-Firby novel and commercial fungal cellulases. Appl Biochem Biotechnol. 2005; 121-124:219-30. PMID: 15917601.
      View in: PubMed