-
Membrane phospholipids activate the inflammatory response in macrophages by various mechanisms. FASEB J. 2024 Apr 30; 38(8):e23619.
Cauvi DM, Hawisher D, Derunes J, Rodriguez E, De Maio A. PMID: 38661031.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Human HSP70-escort protein 1 (hHep1) interacts with negatively charged lipid bilayers and cell membranes. Cell Stress Chaperones. 2023 11; 28(6):1001-1012.
Moritz MNO, Dores-Silva PR, Coto ALS, Selistre-de-Araújo HS, Leitão A, Cauvi DM, De Maio A, Carra S, Borges JC. PMID: 38001371; PMCID: PMC10746634.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired. Nat Commun. 2023 08 18; 14(1):5031.
Liang W, Sagar S, Ravindran R, Najor RH, Quiles JM, Chi L, Diao RY, Woodall BP, Leon LJ, Zumaya E, Duran J, Cauvi DM, De Maio A, Adler ED, Gustafsson ÅB. PMID: 37596294; PMCID: PMC10439183.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
The Small GTPase Rab7 Regulates Release of Mitochondria in Extracellular Vesicles in Response to Lysosomal Dysfunction. bioRxiv. 2023 Feb 13.
Liang W, Diao RY, Quiles JM, Najor RH, Chi L, Woodall BP, Leon LJ, Duran J, Cauvi DM, De Maio A, Adler ED, Gustafsson ÃSB. PMID: 36824711; PMCID: PMC9949095.
View in:
PubMed Mentions:
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Phosphatidylcholine Liposomes Reprogram Macrophages toward an Inflammatory Phenotype. Membranes (Basel). 2023 Jan 21; 13(2).
Cauvi DM, Hawisher D, Derunes J, De Maio A. PMID: 36837644; PMCID: PMC9968183.
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PubMed Mentions:
2
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Elemental, fatty acid, and protein composition of appendicoliths. Sci Rep. 2022 11 17; 12(1):19764.
Prieto JM, Wang AW, Halbach J, Cauvi DM, Day JMD, Gembicky M, Ghassemian M, Quehenberger O, Kling K, Ignacio R, DeMaio A, Bickler SW. PMID: 36396724; PMCID: PMC9671961.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Extremes of age are associated with differences in the expression of selected pattern recognition receptor genes and ACE2, the receptor for SARS-CoV-2: implications for the epidemiology of COVID-19 disease. BMC Med Genomics. 2021 05 24; 14(1):138.
Bickler SW, Cauvi DM, Fisch KM, Prieto JM, Sykes AG, Thangarajah H, Lazar DA, Ignacio RC, Gerstmann DR, Ryan AF, Bickler PE, De Maio A. PMID: 34030677; PMCID: PMC8142073.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Human heat shock cognate protein (HSC70/HSPA8) interacts with negatively charged phospholipids by a different mechanism than other HSP70s and brings HSP90 into membranes. Cell Stress Chaperones. 2021 07; 26(4):671-684.
Dores-Silva PR, Cauvi DM, Coto ALS, Silva NSM, Borges JC, De Maio A. PMID: 34003451; PMCID: PMC8129608.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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New insights on human Hsp70-escort protein 1: Chaperone activity, interaction with liposomes, cellular localizations and HSPA's self-assemblies remodeling. Int J Biol Macromol. 2021 Jul 01; 182:772-784.
Dores-Silva PR, Kiraly VTR, Moritz MNO, Serrão VHB, Dos Passos PMS, Spagnol V, Teixeira FR, Gava LM, Cauvi DM, Ramos CHI, De Maio A, Borges JC. PMID: 33857516.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Regulation of the Nfkbiz Gene and Its Protein Product IkBζ in Animal Models of Sepsis and Endotoxic Shock. Infect Immun. 2021 03 17; 89(4).
Casas A, Hawisher D, De Guzman CB, Bickler SW, De Maio A, Cauvi DM. PMID: 33431705; PMCID: PMC8090956.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Mechanisms of Environment-Induced Autoimmunity. Annu Rev Pharmacol Toxicol. 2021 01 06; 61:135-157.
Pollard KM, Cauvi DM, Mayeux JM, Toomey CB, Peiss AK, Hultman P, Kono DH. PMID: 32857688; PMCID: PMC8166384.
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PubMed Mentions:
12 Fields:
Translation:
HumansPHPublic Health
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Human HSPA9 (mtHsp70, mortalin) interacts with lipid bilayers containing cardiolipin, a major component of the inner mitochondrial membrane. Biochim Biophys Acta Biomembr. 2020 11 01; 1862(11):183436.
Dores-Silva PR, Cauvi DM, Kiraly VTR, Borges JC, De Maio A. PMID: 32781155.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Interaction of HSPA5 (Grp78, BIP) with negatively charged phospholipid membranes via oligomerization involving the N-terminal end domain. Cell Stress Chaperones. 2020 11; 25(6):979-991.
Dores-Silva PR, Cauvi DM, Coto ALS, Kiraly VTR, Borges JC, De Maio A. PMID: 32725381; PMCID: PMC7385938.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCellsPHPublic Health
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Differential expression of nuclear genes encoding mitochondrial proteins from urban and rural populations in Morocco. Cell Stress Chaperones. 2020 11; 25(6):847-856.
Bickler SW, Prieto JM, Cauvi DM, De Cos V, Nasamran C, Ameh E, Amin S, Nicholson S, Din H, Mocumbi AO, Noormahomed EV, Tellez-Isaias G, Fisch KM, De Maio A. PMID: 32319023; PMCID: PMC7591688.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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The Greater Omentum-A Vibrant and Enigmatic Immunologic Organ Involved in Injury and Infection Resolution. Shock. 2020 04; 53(4):384-390.
Wang AW, Prieto JM, Cauvi DM, Bickler SW, De Maio A. PMID: 31389904; PMCID: PMC7000303.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Thermal aggregates of human mortalin and Hsp70-1A behave as supramolecular assemblies. Int J Biol Macromol. 2020 Mar 01; 146:320-331.
Kiraly VTR, Dores-Silva PR, Serrão VHB, Cauvi DM, De Maio A, Borges JC. PMID: 31899237; PMCID: PMC7024674.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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The Contribution of the Omentum to the Outcome From Sepsis: An Experimental Animal Study. Shock. 2019 12; 52(6):604-611.
Wang AW, Cauvi DM, Hawisher D, Reyes T, Coimbra R, Bickler S, De Maio A. PMID: 30601409; PMCID: PMC6588511.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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The small heat shock proteins, HSPB1 and HSPB5, interact differently with lipid membranes. Cell Stress Chaperones. 2019 09; 24(5):947-956.
De Maio A, Cauvi DM, Capone R, Bello I, Egberts WV, Arispe N, Boelens W. PMID: 31338686; PMCID: PMC6717221.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Early hyperbaric oxygen therapy improves survival in a model of severe sepsis. Am J Physiol Regul Integr Comp Physiol. 2019 07 01; 317(1):R160-R168.
Halbach JL, Prieto JM, Wang AW, Hawisher D, Cauvi DM, Reyes T, Okerblom J, Ramirez-Sanchez I, Villarreal F, Patel HH, Bickler SW, Perdrizet GA, De Maio A. PMID: 31091156; PMCID: PMC6692752.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Mercury-induced inflammation and autoimmunity. Biochim Biophys Acta Gen Subj. 2019 12; 1863(12):129299.
Pollard KM, Cauvi DM, Toomey CB, Hultman P, Kono DH. PMID: 30742953; PMCID: PMC6689266.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimals
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Nitrendipine, an antihypertensive alpha calcium channel blocker, is cytotoxic to neuroblastoma cells. Molecular & Cellular Toxicology. 2019; 15:469-475.
Rivera I, Cauvi DM, Arispe N, De Maio A.
-
Macrophage reprogramming by negatively charged membrane phospholipids controls infection. FASEB J. 2019 02; 33(2):2995-3009.
Cauvi DM, Hawisher D, Dores-Silva PR, Lizardo RE, De Maio A. PMID: 30325674; PMCID: PMC6338646.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Urbanization in Sub-Saharan Africa: Declining Rates of Chronic and Recurrent Infection and Their Possible Role in the Origins of Non-communicable Diseases. World J Surg. 2018 06; 42(6):1617-1628.
Bickler SW, Wang A, Amin S, Halbach J, Lizardo R, Cauvi DM, De Maio A. PMID: 29234849; PMCID: PMC5935558.
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PubMed Mentions:
15 Fields:
Translation:
Humans
-
Isolation and characterization of human urine extracellular vesicles. Cell Stress Chaperones. 2018 09; 23(5):943-953.
Liu Z, Cauvi DM, Bernardino EMA, Lara B, Lizardo RE, Hawisher D, Bickler S, De Maio A. PMID: 29796787; PMCID: PMC6111092.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Environmental Xenobiotic Exposure and Autoimmunity. Curr Opin Toxicol. 2018 Aug; 10:15-22.
Pollard KM, Christy JM, Cauvi DM, Kono DH. PMID: 29503968; PMCID: PMC5831116.
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PubMed Mentions:
20
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Why Antibiotic Treatment Is Not Enough for Sepsis Resolution: an Evaluation in an Experimental Animal Model. Infect Immun. 2017 12; 85(12).
Halbach JL, Wang AW, Hawisher D, Cauvi DM, Lizardo RE, Rosas J, Reyes T, Escobedo O, Bickler SW, Coimbra R, De Maio A. PMID: 28947644; PMCID: PMC5695106.
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PubMed Mentions:
18 Fields:
Translation:
Animals
-
Modulation of Alzheimer's amyloid β peptide oligomerization and toxicity by extracellular Hsp70. Cell Stress Chaperones. 2018 03; 23(2):269-279.
Rivera I, Capone R, Cauvi DM, Arispe N, De Maio A. PMID: 28956268; PMCID: PMC5823807.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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From the Cover: Interplay Between IFN-γ and IL-6 Impacts the Inflammatory Response and Expression of Interferon-Regulated Genes in Environmental-Induced Autoimmunity. Toxicol Sci. 2017 07 01; 158(1):227-239.
Cauvi DM, Cauvi G, Toomey CB, Jacquinet E, Pollard KM. PMID: 28453771; PMCID: PMC6075572.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Grape seed proanthocyanidin extract protects lymphocytes against histone-induced apoptosis. PeerJ. 2017; 5:e3108.
Chang P, Mo B, Cauvi DM, Yu Y, Guo Z, Zhou J, Huang Q, Yan Q, Chen G, Liu Z. PMID: 28344907; PMCID: PMC5363264.
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PubMed Mentions:
5 Fields:
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The transition from a rural to an urban environment in Africa alters G protein-coupled receptor signaling. Med Hypotheses. 2016 Oct; 95:49-53.
Bickler SW, Lizardo E, Cauvi DM, De Maio A. PMID: 27692166.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Bacterial Hsp70 (DnaK) and mammalian Hsp70 interact differently with lipid membranes. Cell Stress Chaperones. 2016 07; 21(4):609-16.
Lopez V, Cauvi DM, Arispe N, De Maio A. PMID: 27075190; PMCID: PMC4907991.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Changes in macrophage function modulated by the lipid environment. Innate Immun. 2016 Apr; 22(3):141-51.
Williams MR, Cauvi DM, Rivera I, Hawisher D, De Maio A. PMID: 26951856; PMCID: PMC5102337.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Pulmonary preconditioning, injury, and inflammation modulate expression of the candidate tumor suppressor gene ECRG4 in lung. Exp Lung Res. 2015 Apr; 41(3):162-72.
Kao S, Shaterian A, Cauvi DM, Dang X, Chun HB, De Maio A, Costantini TW, Coimbra R, Eliceiri BP, Baird A. PMID: 25513848; PMCID: PMC4524537.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Cathepsin B regulates the appearance and severity of mercury-induced inflammation and autoimmunity. Toxicol Sci. 2014 Dec; 142(2):339-49.
Toomey CB, Cauvi DM, Hamel JC, Ramirez AE, Pollard KM. PMID: 25237059; PMCID: PMC4250846.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Sustained expression of lipocalin-2 during polymicrobial sepsis. Innate Immun. 2015 Jul; 21(5):477-89.
Vazquez DE, Niño DF, De Maio A, Cauvi DM. PMID: 25227123.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Elevated expression of IL-23/IL-17 pathway-related mediators correlates with exacerbation of pulmonary inflammation during polymicrobial sepsis. Shock. 2014 Sep; 42(3):246-55.
Cauvi DM, Williams MR, Bermudez JA, Armijo G, De Maio A. PMID: 24978886; PMCID: PMC4134380.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Itraconazole, a commonly used antifungal, inhibits Fcγ receptor-mediated phagocytosis: alteration of Fcγ receptor glycosylation and gene expression. Shock. 2014 Jul; 42(1):52-9.
Niño DF, Cauvi DM, De Maio A. PMID: 24667630; PMCID: PMC4071940.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Interaction of heat shock protein 70 with membranes depends on the lipid environment. Cell Stress Chaperones. 2014 Nov; 19(6):877-86.
Armijo G, Okerblom J, Cauvi DM, Lopez V, Schlamadinger DE, Kim J, Arispe N, De Maio A. PMID: 24789271; PMCID: PMC4389847.
View in:
PubMed Mentions:
31 Fields:
Translation:
Cells
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A tandem repeat in decay accelerating factor 1 is associated with severity of murine mercury-induced autoimmunity. Autoimmune Dis. 2014; 2014:260613.
Cauvi DM, Gabriel R, Kono DH, Hultman P, Pollard KM. PMID: 24818014; PMCID: PMC4003777.
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PubMed Mentions:
1
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The role of decay accelerating factor in environmentally induced and idiopathic systemic autoimmune disease. Autoimmune Dis. 2014; 2014:452853.
Toomey CB, Cauvi DM, Pollard KM. PMID: 24592327; PMCID: PMC3921935.
View in:
PubMed Mentions:
8
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Interferon-γ and systemic autoimmunity. Discov Med. 2013 Sep; 16(87):123-31.
Pollard KM, Cauvi DM, Toomey CB, Morris KV, Kono DH. PMID: 23998448; PMCID: PMC3934799.
View in:
PubMed Mentions:
137 Fields:
Translation:
HumansAnimals
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Deletion of scavenger receptor A gene in mice resulted in protection from septic shock and modulation of TLR4 signaling in isolated peritoneal macrophages. Innate Immun. 2013 Feb; 19(1):30-41.
Drummond R, Cauvi DM, Hawisher D, Song D, Niño DF, Coimbra R, Bickler S, De Maio A. PMID: 22751446; PMCID: PMC4349423.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity. J Autoimmun. 2012 Dec; 39(4):323-31.
Pollard KM, Hultman P, Toomey CB, Cauvi DM, Hoffman HM, Hamel JC, Kono DH. PMID: 22578563; PMCID: PMC3570757.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Period of irreversible therapeutic intervention during sepsis correlates with phase of innate immune dysfunction. J Biol Chem. 2012 Jun 08; 287(24):19804-15.
Cauvi DM, Song D, Vazquez DE, Hawisher D, Bermudez JA, Williams MR, Bickler S, Coimbra R, De Maio A. PMID: 22518839; PMCID: PMC3370166.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
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Depletion of complement does not impact initiation of xenobiotic-induced autoimmune disease. Immunology. 2012 Apr; 135(4):333-43.
Cauvi DM, Toomey CB, Pollard KM. PMID: 22136142; PMCID: PMC3372748.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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β2-microglobulin is required for the full expression of xenobiotic-induced systemic autoimmunity. J Immunotoxicol. 2011 Jul-Sep; 8(3):228-37.
Pollard KM, Hultman P, Toomey CB, Cauvi DM, Kono DH, Konoc DH. PMID: 21793797; PMCID: PMC3257888.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Acute acalculous cholecystitis-like phenotype in scavenger receptor A knock-out mice. J Surg Res. 2012 May 15; 174(2):344-51.
Drummond R, Song D, Hawisher D, Wolf PL, Vazquez DE, Nino DF, Coimbra R, Cauvi DM, De Maio A. PMID: 21474146; PMCID: PMC3173564.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Tumor necrosis factor expression is ameliorated after exposure to an acidic environment. J Surg Res. 2012 Mar; 173(1):127-34.
Grabowski J, Vazquez DE, Costantini T, Cauvi DM, Charles W, Bickler S, Talamini MA, Vega VL, Coimbra R, De Maio A. PMID: 20888586; PMCID: PMC3017641.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Decay-accelerating factor 1 (Daf1) deficiency exacerbates xenobiotic-induced autoimmunity. Immunology. 2010 Sep; 131(1):99-106.
Toomey CB, Cauvi DM, Song WC, Pollard KM. PMID: 20408894; PMCID: PMC2966762.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Reduced expression of decay-accelerating factor 1 on CD4+ T cells in murine systemic autoimmune disease. Arthritis Rheum. 2007 Jun; 56(6):1934-44.
Cauvi DM, Cauvi G, Pollard KM. PMID: 17530719.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Constitutive expression of murine decay-accelerating factor 1 is controlled by the transcription factor Sp1. J Immunol. 2006 Sep 15; 177(6):3837-47.
Cauvi DM, Cauvi G, Pollard KM. PMID: 16951346; PMCID: PMC1766464.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Transport of the IgE receptor alpha-chain is controlled by a multicomponent intracellular retention signal. J Biol Chem. 2006 Apr 14; 281(15):10448-60.
Cauvi DM, Tian X, von Loehneysen K, Robertson MW. PMID: 16459334.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Role of sulfated tyrosines of thyroglobulin in thyroid hormonosynthesis. Endocrinology. 2005 Nov; 146(11):4834-43.
Nlend MC, Cauvi DM, Venot N, Chabaud O. PMID: 16037381.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Thyrotropin and iodide regulate sulfate concentration in thyroid cells. Relationship to thyroglobulin sulfation. Can J Physiol Pharmacol. 2003 Dec; 81(12):1131-8.
Cauvi D, Venot N, Nlend MC, Chabaud OM. PMID: 14719032.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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The hormonogenic tyrosine 5 of porcine thyroglobulin is sulfated. Biochem Biophys Res Commun. 2002 Oct 25; 298(2):193-7.
Venot N, Nlend MC, Cauvi D, Chabaud O. PMID: 12387814.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Sulfate transport in porcine thyroid cells. Effects of thyrotropin and iodide. Am J Physiol Endocrinol Metab. 2001 Sep; 281(3):E440-8.
Cauvi D, Nlend MC, Venot N, Chabaud O. PMID: 11500298.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Regulation of thyroid cell volumes and fluid transport: opposite effects of TSH and iodide on cultured cells. Am J Physiol Endocrinol Metab. 2000 Sep; 279(3):E546-53.
Cauvi D, Penel C, Nlend MC, Venot N, Allasia C, Chabaud O. PMID: 10950821.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Sulfated tyrosines of thyroglobulin are involved in thyroid hormone synthesis. Biochem Biophys Res Commun. 1999 Aug 19; 262(1):193-7.
Nlend MC, Cauvi D, Venot N, Chabaud O. PMID: 10448091.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Thyrotropin regulates tyrosine sulfation of thyroglobulin. Eur J Endocrinol. 1999 Jul; 141(1):61-9.
Nlend MC, Cauvi D, Venot N, Desruisseau S, Chabaud O. PMID: 10407225.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells