Daniel Hollern

Title(s)Assistant Adjunct Professor, Molecular Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Identifying Effective Immune Checkpoint Therapy Strategies in Triple Negative Breast Cancer
    NIH F32CA210427Aug 1, 2016 - Jul 31, 2019
    Role: Principal Investigator
    Illuminating the E2F Transcription Factors Control of Breast Cancer Metastasis
    NIH F31CA183272Sep 15, 2014 - Sep 14, 2015
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sensitivity to targeted therapy differs between HER2-amplified breast cancer cells harboring kinase and helical domain mutations in PIK3CA. Breast Cancer Res. 2021 08 03; 23(1):81. Garay JP, Smith R, Devlin K, Hollern DP, Liby T, Liu M, Boddapati S, Watson SS, Esch A, Zheng T, Thompson W, Babcock D, Kwon S, Chin K, Heiser L, Gray JW, Korkola JE. PMID: 34344439.
      View in: PubMed   Mentions:    Fields:    
    2. FOXA1 overexpression suppresses interferon signaling and immune response in cancer. J Clin Invest. 2021 07 15; 131(14). He Y, Wang L, Wei T, Xiao YT, Sheng H, Su H, Hollern DP, Zhang X, Ma J, Wen S, Xie H, Yan Y, Pan Y, Hou X, Tang X, Suman VJ, Carter JM, Weinshilboum R, Wang L, Kalari KR, Weroha SJ, Bryce AH, Boughey JC, Dong H, Perou CM, Ye D, Goetz MP, Ren S, Huang H. PMID: 34101624.
      View in: PubMed   Mentions: 1     Fields:    
    3. PDGFRβ is an essential therapeutic target for BRCA1-deficient mammary tumors. Breast Cancer Res. 2021 01 21; 23(1):10. Bai F, Liu S, Liu X, Hollern DP, Scott A, Wang C, Zhang L, Fan C, Fu L, Perou CM, Zhu WG, Pei XH. PMID: 33478572.
      View in: PubMed   Mentions: 1     Fields:    
    4. FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease. J Clin Invest. 2020 09 01; 130(9):4871-4887. Garcia-Recio S, Thennavan A, East MP, Parker JS, Cejalvo JM, Garay JP, Hollern DP, He X, Mott KR, Galván P, Fan C, Selitsky SR, Coffey AR, Marron D, Brasó-Maristany F, Burgués O, Albanell J, Rojo F, Lluch A, de Dueñas EM, Rosen JM, Johnson GL, Carey LA, Prat A, Perou CM. PMID: 32573490.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    5. Stimulation of Oncogene-Specific Tumor-Infiltrating T Cells through Combined Vaccine and αPD-1 Enable Sustained Antitumor Responses against Established HER2 Breast Cancer. Clin Cancer Res. 2020 09 01; 26(17):4670-4681. Crosby EJ, Acharya CR, Haddad AF, Rabiola CA, Lei G, Wei JP, Yang XY, Wang T, Liu CX, Wagner KU, Muller WJ, Chodosh LA, Broadwater G, Hyslop T, Shepherd JH, Hollern DP, He X, Perou CM, Chai S, Ashby BK, Vincent BG, Snyder JC, Force J, Morse MA, Lyerly HK, Hartman ZC. PMID: 32732224.
      View in: PubMed   Mentions: 4     Fields:    
    6. NCOA5 deficiency promotes a unique liver protumorigenic microenvironment through p21WAF1/CIP1 overexpression, which is reversed by metformin. Oncogene. 2020 05; 39(19):3821-3836. Williams M, Liu X, Zhang Y, Reske J, Bahal D, Gohl TG, Hollern D, Ensink E, Kiupel M, Luo R, Das R, Xiao H. PMID: 32203160.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    7. Virus expression detection reveals RNA-sequencing contamination in TCGA. BMC Genomics. 2020 Jan 28; 21(1):79. Selitsky SR, Marron D, Hollern D, Mose LE, Hoadley KA, Jones C, Parker JS, Dittmer DP, Perou CM. PMID: 31992194.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    8. B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer. Cell. 2019 11 14; 179(5):1191-1206.e21. Hanna RF, Ward TJ, Chow DS, Lagana SM, Moreira RK, Emond JC, Weintraub JL, Prince MR, Hollern DP, Xu N, Thennavan A, Glodowski C, Garcia-Recio S, Mott KR, He X, Garay JP, Carey-Ewend K, Marron D, Ford J, Liu S, Vick SC, Martin M, Parker JS, Vincent BG, Serody JS, Perou CM. PMID: 31730857; PMCID: PMC6911685.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    9. E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration. Sci Rep. 2019 07 24; 9(1):10718. Hollern DP, Swiatnicki MR, Rennhack JP, Misek SA, Matson BC, McAuliff A, Gallo KA, Caron KM, Andrechek ER. PMID: 31341204.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    10. Identification of Jun loss promotes resistance to histone deacetylase inhibitor entinostat through Myc signaling in luminal breast cancer. Genome Med. 2018 11 30; 10(1):86. Tanioka M, Mott KR, Hollern DP, Fan C, Darr DB, Perou CM. PMID: 30497520.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    11. A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer. Breast Cancer Res Treat. 2019 Feb; 174(1):143-155. Hollern DP, Contreras CM, Dance-Barnes S, Silva GO, Pfefferle AD, Xiong J, Darr DB, Usary J, Mott KR, Perou CM. PMID: 30484104.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    12. Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast. Cell Rep. 2018 10 16; 25(3):702-714.e6. An Y, Adams JR, Hollern DP, Zhao A, Chang SG, Gams MS, Chung PED, He X, Jangra R, Shah JS, Yang J, Beck LA, Raghuram N, Kozma KJ, Loch AJ, Wang W, Fan C, Done SJ, Zacksenhaus E, Guidos CJ, Perou CM, Egan SE. PMID: 30332649.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    13. A Review of FOXI3 Regulation of Development and Possible Roles in Cancer Progression and Metastasis. Front Cell Dev Biol. 2018; 6:69. Mukherjee A, Hollern DP, Williams OG, Rayburn TS, Byrd WA, Yates C, Jones JD. PMID: 30018953.
      View in: PubMed   Mentions:
    14. Integrated Molecular Characterization of Testicular Germ Cell Tumors. Cell Rep. 2018 06 12; 23(11):3392-3406. Shen H, Shih J, Hollern DP, Wang L, Bowlby R, Tickoo SK, Thorsson V, Mungall AJ, Newton Y, Hegde AM, Armenia J, Sánchez-Vega F, Pluta J, Pyle LC, Mehra R, Reuter VE, Godoy G, Jones J, Shelley CS, Feldman DR, Vidal DO, Lessel D, Kulis T, Cárcano FM, Leraas KM, Lichtenberg TM, Brooks D, Cherniack AD, Cho J, Heiman DI, Kasaian K, Liu M, Noble MS, Xi L, Zhang H, Zhou W, ZenKlusen JC, Hutter CM, Felau I, Zhang J, Schultz N, Getz G, Meyerson M, Stuart JM, Cancer Genome Atlas Research Network , Akbani R, Wheeler DA, Laird PW, Nathanson KL, Cortessis VK, Hoadley KA. PMID: 29898407.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    15. Histological subtypes of mouse mammary tumors reveal conserved relationships to human cancers. PLoS Genet. 2018 01; 14(1):e1007135. Hollern DP, Swiatnicki MR, Andrechek ER. PMID: 29346386.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    16. LPA receptor activity is basal specific and coincident with early pregnancy and involution during mammary gland postnatal development. Sci Rep. 2016 11 03; 6:35810. Acosta D, Bagchi S, Broin PÓ, Hollern D, Racedo SE, Morrow B, Sellers RS, Greally JM, Golden A, Andrechek E, Wood T, Montagna C. PMID: 27808166.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    17. Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation. Mol Cell. 2015 Jan 08; 57(1):95-107. Lunt SY, Muralidhar V, Hosios AM, Israelsen WJ, Gui DY, Newhouse L, Ogrodzinski M, Hecht V, Xu K, Acevedo PN, Hollern DP, Bellinger G, Dayton TL, Christen S, Elia I, Dinh AT, Stephanopoulos G, Manalis SR, Yaffe MB, Andrechek ER, Fendt SM, Vander Heiden MG. PMID: 25482511.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    18. The E2F transcription factors regulate tumor development and metastasis in a mouse model of metastatic breast cancer. Mol Cell Biol. 2014 Sep; 34(17):3229-43. Hollern DP, Honeysett J, Cardiff RD, Andrechek ER. PMID: 24934442.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    19. A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer. Breast Cancer Res. 2014 Jun 05; 16(3):R59. Hollern DP, Andrechek ER. PMID: 25069779.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    20. Prediction and genetic demonstration of a role for activator E2Fs in Myc-induced tumors. Cancer Res. 2011 Mar 01; 71(5):1924-32. Fujiwara K, Yuwanita I, Hollern DP, Andrechek ER. PMID: 21245101.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
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