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Leslie Kobayashi

Title(s)Associate Professor Of Clinical, Surgery
SchoolHealth Sciences
Phone619-543-5805
Emaillkobayashi@ucsd.edu
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    Collapse Overview 
    Collapse Overview
    Dr. Kobayashi joined the Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery at UC San Diego in August 2010 as an assistant professor of clinical surgery. Her current duties include clinical care in the outpatient, inpatient and intensive care setting as an attending physician on the Trauma, General Surgery and Surgical Intensive Care Services.

    Dr. Kobayashi is dedicated to teaching medical students, residents and critical care fellows. She is also involved in teaching in the community as an instructor for the many Advanced Trauma Operative Management (ATOM) and Advanced Trauma Life Support (ATLS) courses offered at UC San Diego every year.

    Dr. Kobayashi earned her medical degree at the University of Colorado Health Sciences Center where she had the opportunity to train under the tutelage of some of the most influential surgeons in the field of trauma including Dr. C. Cothren, Dr. J. Johnson, and Drs. Earnest and JB Moore at the Denver Health Medical Center. She completed her internship and residency in general surgery at the University of Southern California in Los Angeles. She completed advanced training in a Trauma/Critical Care fellowship at Los Angeles County+USC Medical Center. LAC+USC is a busy Level I trauma center with an Acute Care Surgery model run by the Division of Trauma and Surgical Critical Care.

    Dr. Kobayashi's training included a dedication to hands-on clinical teaching at all levels, including pre-medical volunteers, medical students and residents. Additionally, the unique collaboration between LAC+USC and the U.S. Naval Trauma Training Center allowed her to be involved in the training of multiple groups of corpsmen, nurses, physicians and physician extenders in preparation for their deployment to active military conflict zones. Additionally, she has experience with other teaching modalities including: didactic teaching during journal clubs, core lectures and medical student lectures, both didactic and skills-based teaching as an ATLS and ATOM instructor, and module-based teaching as an instructor in the Fundamentals of Critical Care Course taught by the Society of Critical Care Medicine.

    Research Overview
    My research focuses on clinical questions in trauma management, particularly traumatic brain injury, management of the potential organ donor, and venous thromboembolic complications in trauma and the ICU.

    Research Topics
    - Trauma

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Coccolini F, Kobayashi L, Kluger Y, Moore EE, Ansaloni L, Biffl W, Leppaniemi A, Augustin G, Reva V, Wani I, Kirkpatrick A, Abu-Zidan F, Cicuttin E, Fraga GP, Ordonez C, Pikoulis E, Sibilla MG, Maier R, Matsumura Y, Masiakos PT, Khokha V, Mefire AC, Ivatury R, Favi F, Manchev V, Sartelli M, Machado F, Matsumoto J, Chiarugi M, Arvieux C, Catena F, Coimbra R. Duodeno-pancreatic and extrahepatic biliary tree trauma: WSES-AAST guidelines. World J Emerg Surg. 2019; 14:56. PMID: 31867050.
      View in: PubMed
    2. Ballon-Landa E, Raheem OA, Fuller TW, Kobayashi L, Buckley JC. Renal Trauma Classification and Management: Validating the Revised Renal Injury Grading Scale. J Urol. 2019 11; 202(5):994-1000. PMID: 31144592.
      View in: PubMed
    3. Ballon-Landa E, Raheem OA, Fuller TW, Kobayashi L, Buckley JC. Reply by Authors. J Urol. 2019 11; 202(5):1000. PMID: 31766096.
      View in: PubMed
    4. Kobayashi LM, Williams E, Brown CV, Emigh BJ, Bansal V, Badiee J, Checchi KD, Castillo EM, Doucet J. The e-merging e-pidemic of e-scooters. Trauma Surg Acute Care Open. 2019; 4(1):e000337. PMID: 31565677.
      View in: PubMed
    5. Savage SA, Li SW, Utter GH, Cox JA, Wydo SM, Cahill K, Sarani B, Holzmacher J, Duane TM, Gandhi RR, Zielinski MD, Ray-Zack M, Tierney J, Chapin T, Murphy PB, Vogt KN, Schroeppel TJ, Callaghan E, Kobayashi L, Coimbra R, Schuster KM, Gillaspie D, Timsina L, Louis A, Crandall M. The EGS grading scale for skin and soft-tissue infections is predictive of poor outcomes: a multicenter validation study. J Trauma Acute Care Surg. 2019 Apr; 86(4):601-608. PMID: 30601458.
      View in: PubMed
    6. Kobayashi LM, Brito A, Barmparas G, Bosarge P, Brown CV, Bukur M, Carrick MM, Catalano RD, Holly-Nicolas J, Inaba K, Kaminski S, Klein AL, Kopelman T, Ley EJ, Martinez EM, Moore FO, Murry J, Nirula R, Paul D, Quick J, Rivera O, Schreiber M, Coimbra R. Laboratory measures of coagulation among trauma patients on NOAs: results of the AAST-MIT. Trauma Surg Acute Care Open. 2018; 3(1):e000231. PMID: 30402564.
      View in: PubMed
    7. Barmparas G, Kobayashi L, Dhillon NK, Patel KA, Ley EJ, Coimbra R, Margulies DR. The risk of delayed intracranial hemorrhage with direct acting oral anticoagulants after trauma: A two-center study. Am J Surg. 2019 Jun; 217(6):1051-1054. PMID: 30336936.
      View in: PubMed
    8. Godat LN, Kobayashi LM, Chang DC, Coimbra R. Improving life expectancy: A 'broken neck' doesn't have to be a terminal diagnosis for the elderly. Trauma Surg Acute Care Open. 2018; 3(1):e000174. PMID: 29766142.
      View in: PubMed
    9. Kobayashi L, Barmparas G, Bosarge P, Brown CV, Bukur M, Carrick MM, Catalano RD, Holly-Nicolas J, Inaba K, Kaminski S, Klein AL, Kopelman T, Ley EJ, Martinez EM, Moore FO, Murry J, Nirula R, Paul D, Quick J, Rivera O, Schreiber M, Coimbra R. Novel oral anticoagulants and trauma: The results of a prospective American Association for the Surgery of Trauma Multi-Institutional Trial. J Trauma Acute Care Surg. 2017 05; 82(5):827-835. PMID: 28431413.
      View in: PubMed
    10. Berndtson AE, Costantini TW, Smith AM, Kobayashi L, Coimbra R. Does sex matter? Effects on venous thromboembolism risk in screened trauma patients. J Trauma Acute Care Surg. 2016 09; 81(3):493-9. PMID: 27280942.
      View in: PubMed
    11. Kobayashi LM, Costantini TW, Hamel MG, Dierksheide JE, Coimbra R. Abdominal vascular trauma. Trauma Surg Acute Care Open. 2016; 1(1):e000015. PMID: 29766059.
      View in: PubMed
    12. Berndtson AE, Huang WT, Box K, Kobayashi L, Godat LN, Smith AM, Weingarten D, Coimbra R. A new kid on the block: Outcomes with Kcentra 1 year after approval. J Trauma Acute Care Surg. 2015 Dec; 79(6):1004-8. PMID: 26488322.
      View in: PubMed
    13. Bulger EM, May A, Bernard A, Cohn S, Evans DC, Henry S, Quick J, Kobayashi L, Foster K, Duane TM, Sawyer RG, Kellum JA, Maung A, Maislin G, Smith DD, Segalovich I, Dankner W, Shirvan A. Impact and Progression of Organ Dysfunction in Patients with Necrotizing Soft Tissue Infections: A Multicenter Study. Surg Infect (Larchmt). 2015 Dec; 16(6):694-701. PMID: 26381131.
      View in: PubMed
    14. Evans CS, Smith S, Kobayashi L, Chang DC. The Effect of Community Health Center (CHC) Density on Preventable Hospital Admissions in Medicaid and Uninsured Patients. J Health Care Poor Underserved. 2015 Aug; 26(3):839-51. PMID: 26320918.
      View in: PubMed
    15. Inaba K, Nosanov L, Menaker J, Bosarge P, Williams L, Turay D, Cachecho R, de Moya M, Bukur M, Carl J, Kobayashi L, Kaminski S, Beekley A, Gomez M, Skiada D. Prospective derivation of a clinical decision rule for thoracolumbar spine evaluation after blunt trauma: An American Association for the Surgery of Trauma Multi-Institutional Trials Group Study. J Trauma Acute Care Surg. 2015 Mar; 78(3):459-65; discussion 465-7. PMID: 25710414.
      View in: PubMed
    16. Godat LN, Kobayashi L, Chang DC, Coimbra R. Can we ever stop worrying about venous thromboembolism after trauma? J Trauma Acute Care Surg. 2015 Mar; 78(3):475-80; discussion 480-1. PMID: 25710416.
      View in: PubMed
    17. Kim DY, Kobayashi L, Chang D, Fortlage D, Coimbra R. Early pharmacological venous thromboembolism prophylaxis is safe after operative fixation of traumatic spine fractures. Spine (Phila Pa 1976). 2015 Mar 01; 40(5):299-304. PMID: 25901977.
      View in: PubMed
    18. Bansal V, Reid CM, Fortlage D, Lee J, Kobayashi L, Doucet J, Coimbra R. Determining injuries from posterior and flank stab wounds using computed tomography tractography. Am Surg. 2014 Apr; 80(4):403-7. PMID: 24887674.
      View in: PubMed
    19. Kobayashi L, Coimbra R. Planned re-laparotomy and the need for optimization of physiology and immunology. Eur J Trauma Emerg Surg. 2014 Apr; 40(2):135-42. PMID: 26815893.
      View in: PubMed
    20. Godat L, Kobayashi L, Chang DC, Coimbra R. Do trauma stomas ever get reversed? J Am Coll Surg. 2014 Jul; 219(1):70-77.e1. PMID: 24862884.
      View in: PubMed
    21. Prendergast C, Hassanein AH, Bansal V, Kobayashi L. Shock with intestinal ischemia: a rare complication of methamphetamine use. Am Surg. 2014 Jan; 80(1):101-2. PMID: 24401527.
      View in: PubMed
    22. Kim DY, Regner J, Doucet J, Kobayashi L, Lee J, Coimbra R, Bansal V. Use of ultrasonography during percutaneous endoscopic gastrostomy. Am Surg. 2014 Jan; 80(1):E30-2. PMID: 24401510.
      View in: PubMed
    23. Kim D, Kobayashi L, Chang D, Fortlage D, Coimbra R. Development of a preliminary risk index to identify trauma patients at risk for an unplanned intubation. J Trauma Acute Care Surg. 2014 Jan; 76(1):167-71. PMID: 24368373.
      View in: PubMed
    24. Godat L, Kobayashi L, Costantini T, Coimbra R. Abdominal damage control surgery and reconstruction: world society of emergency surgery position paper. World J Emerg Surg. 2013 Dec 17; 8(1):53. PMID: 24341602.
      View in: PubMed
    25. Schnüriger B, Lam L, Inaba K, Kobayashi L, Barbarino R, Demetriades D. Negative laparotomy in trauma: are we getting better? Am Surg. 2012 Nov; 78(11):1219-23. PMID: 23089438.
      View in: PubMed
    26. Kobayashi L, Costantini TW, Coimbra R. Hypovolemic shock resuscitation. Surg Clin North Am. 2012 Dec; 92(6):1403-23. PMID: 23153876.
      View in: PubMed
    27. Mohseni S, Talving P, Kobayashi L, Kim D, Inaba K, Lam L, Chan LS, Coimbra R, Demetriades D. Closed-suction drain placement at laparotomy in isolated solid organ injury is not associated with decreased risk of deep surgical site infection. Am Surg. 2012 Oct; 78(10):1187-91. PMID: 23025967.
      View in: PubMed
    28. Kim DY, Kobayashi L, Barmparas G, Fortlage D, Curry T, Coimbra R. Venous thromboembolism in the elderly: the result of comorbid conditions or a consequence of injury? J Trauma Acute Care Surg. 2012 May; 72(5):1286-91. PMID: 22673256.
      View in: PubMed
    29. Ramirez M, Chang DC, Rogers SO, Yu PT, Easterlin M, Coimbra R, Kobayashi L. Can universal coverage eliminate health disparities? Reversal of disparate injury outcomes in elderly insured minorities. J Surg Res. 2013 Jun 15; 182(2):264-9. PMID: 23562209.
      View in: PubMed
    30. Regner JL, Kobayashi L, Coimbra R. Surgical strategies for management of the open abdomen. World J Surg. 2012 Mar; 36(3):497-510. PMID: 21847684.
      View in: PubMed
    31. Bukur M, Castelo Branco B, Inaba K, Cestero R, Kobayashi L, Tang A, Demetriades D. The impact of American College of Surgeons trauma center designation and outcomes after early thoracotomy: a National Trauma Databank analysis. Am Surg. 2012 Jan; 78(1):36-41. PMID: 22273303.
      View in: PubMed
    32. Kim DY, Kobayashi L, Costantini TW, Chang D, Fortlage D, Curry T, Wynn S, Doucet J, Bansal V, Coimbra R. Is contrast exposure safe among the highest risk trauma patients? J Trauma Acute Care Surg. 2012 Jan; 72(1):61-6; discussion 66-7. PMID: 22310117.
      View in: PubMed
    33. Chang DC, Anderson JE, Kobayashi L, Coimbra R, Bickler SW. Projected lifetime risks and hospital care expenditure for traumatic injury. J Surg Res. 2012 Aug; 176(2):567-70. PMID: 22261584.
      View in: PubMed
    34. Kobayashi L, Konstantinidis A, Shackelford S, Chan LS, Talving P, Inaba K, Demetriades D. Necrotizing soft tissue infections: delayed surgical treatment is associated with increased number of surgical debridements and morbidity. J Trauma. 2011 Nov; 71(5):1400-5. PMID: 21768906.
      View in: PubMed
    35. Mohseni S, Talving P, Kobayashi L, Lam L, Inaba K, Branco BC, Oliver M, Demetriades D. The diagnostic accuracy of 64-slice computed tomography in detecting clinically significant arterial bleeding after pelvic fractures. Am Surg. 2011 Sep; 77(9):1176-82. PMID: 21944627.
      View in: PubMed
    36. Konstantinidis A, Talving P, Kobayashi L, Barmparas G, Plurad D, Lam L, Inaba K, Demetriades D. Work-related injuries: injury characteristics, survival, and age effect. Am Surg. 2011 Jun; 77(6):702-7. PMID: 21679637.
      View in: PubMed
    37. Lustenberger T, Talving P, Lam L, Kobayashi L, Inaba K, Plurad D, Branco BC, Demetriades D. Unstable cervical spine fracture after penetrating neck injury: a rare entity in an analysis of 1,069 patients. J Trauma. 2011 Apr; 70(4):870-2. PMID: 20805776.
      View in: PubMed
    38. Lopez N, Kobayashi L, Coimbra R. A Comprehensive review of abdominal infections. World J Emerg Surg. 2011 Feb 23; 6:7. PMID: 21345232.
      View in: PubMed
    39. Eberle BM, Schnüriger B, Inaba K, Cestero R, Kobayashi L, Barmparas G, Oliver M, Demetriades D. Thromboembolic prophylaxis with low-molecular-weight heparin in patients with blunt solid abdominal organ injuries undergoing nonoperative management: current practice and outcomes. J Trauma. 2011 Jan; 70(1):141-6; discussion 147. PMID: 21217492.
      View in: PubMed
    40. Lustenberger T, Talving P, Kobayashi L, Barmparas G, Inaba K, Lam L, Branco BC, Demetriades D. Early coagulopathy after isolated severe traumatic brain injury: relationship with hypoperfusion challenged. J Trauma. 2010 Dec; 69(6):1410-4. PMID: 20404754.
      View in: PubMed
    41. Leemann H, Lustenberger T, Talving P, Kobayashi L, Bukur M, Brenni M, Brüesch M, Spahn DR, Keel MJ. The role of rotation thromboelastometry in early prediction of massive transfusion. J Trauma. 2010 Dec; 69(6):1403-8; discussion 1408-9. PMID: 21150521.
      View in: PubMed
    42. Eberle BM, Schnüriger B, Putty B, Barmparas G, Kobayashi L, Inaba K, Belzberg H, Demetriades D. The impact of Acinetobacter baumannii infections on outcome in trauma patients: a matched cohort study. Crit Care Med. 2010 Nov; 38(11):2133-8. PMID: 20802326.
      View in: PubMed
    43. Lustenberger T, Talving P, Kobayashi L, Inaba K, Lam L, Plurad D, Demetriades D. Time course of coagulopathy in isolated severe traumatic brain injury. Injury. 2010 Sep; 41(9):924-8. PMID: 20471013.
      View in: PubMed
    44. DuBose JJ, Kobayashi L, Lozornio A, Teixeira P, Inaba K, Lam L, Talving P, Branco B, Demetriades D, Rhee P. Clinical experience using 5% hypertonic saline as a safe alternative fluid for use in trauma. J Trauma. 2010 May; 68(5):1172-7. PMID: 20453771.
      View in: PubMed
    45. Kobayashi L, Inaba K, Barmparas G, Criscuoli M, Lustenberger T, Talving P, Lam L, Demetriades D. Traumatic limb amputations at a level I trauma center. Eur J Trauma Emerg Surg. 2011 Feb; 37(1):67-72. PMID: 26814753.
      View in: PubMed
    46. Talving P, Lustenberger T, Kobayashi L, Inaba K, Barmparas G, Schnüriger B, Lam L, Chan LS, Demetriades D. Erythropoiesis stimulating agent administration improves survival after severe traumatic brain injury: a matched case control study. Ann Surg. 2010 Jan; 251(1):1-4. PMID: 19779323.
      View in: PubMed
    47. Salim A, Hadjizacharia P, DuBose J, Kobayashi L, Inaba K, Chan LS, Margulies DR. What is the significance of thrombocytosis in patients with trauma? J Trauma. 2009 May; 66(5):1349-54. PMID: 19430238.
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