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Metabolome Changes during In Vivo Red Cell Aging Reveal Disruption of Key Metabolic Pathways. iScience. 2020 Oct 23; 23(10):101630.
Jamshidi N, Xu X, von Löhneysen K, Soldau K, Mohney RP, Karoly ED, Scott M, Friedman JS. PMID: 33103072; PMCID: PMC7575880.
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1
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Prion protein post-translational modifications modulate heparan sulfate binding and limit aggregate size in prion disease. Neurobiol Dis. 2020 08; 142:104955.
Callender JA, Sevillano AM, Soldau K, Kurt TD, Schumann T, Pizzo DP, Altmeppen H, Glatzel M, Esko JD, Sigurdson CJ. PMID: 32454127; PMCID: PMC7425694.
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2 Fields:
Translation:
AnimalsCells
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Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease. J Clin Invest. 2020 03 02; 130(3):1350-1362.
Sevillano AM, Aguilar-Calvo P, Kurt TD, Lawrence JA, Soldau K, Nam TH, Schumann T, Pizzo DP, Nyström S, Choudhury B, Altmeppen H, Esko JD, Glatzel M, Nilsson KPR, Sigurdson CJ. PMID: 31985492; PMCID: PMC7269597.
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6 Fields:
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AnimalsCells
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Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions. Acta Neuropathol. 2020 03; 139(3):527-546.
Aguilar-Calvo P, Sevillano AM, Bapat J, Soldau K, Sandoval DR, Altmeppen HC, Linsenmeier L, Pizzo DP, Geschwind MD, Sanchez H, Appleby BS, Cohen ML, Safar JG, Edland SD, Glatzel M, Nilsson KPR, Esko JD, Sigurdson CJ. PMID: 31673874; PMCID: PMC7036335.
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4 Fields:
Translation:
HumansAnimals
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Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients. mBio. 2018 11 20; 9(6).
Orrù CD, Soldau K, Cordano C, Llibre-Guerra J, Green AJ, Sanchez H, Groveman BR, Edland SD, Safar JG, Lin JH, Caughey B, Geschwind MD, Sigurdson CJ. PMID: 30459197; PMCID: PMC6247090.
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14 Fields:
Translation:
Humans
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Generation of novel neuroinvasive prions following intravenous challenge. Brain Pathol. 2018 11; 28(6):999-1011.
Aguilar-Calvo P, Bett C, Sevillano AM, Kurt TD, Lawrence J, Soldau K, Hammarström P, Nilsson KPR, Sigurdson CJ. PMID: 29505163; PMCID: PMC6123309.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Post-translational modifications in PrP expand the conformational diversity of prions in vivo. Sci Rep. 2017 03 08; 7:43295.
Aguilar-Calvo P, Xiao X, Bett C, Eraña H, Soldau K, Castilla J, Nilsson KP, Surewicz WK, Sigurdson CJ. PMID: 28272426; PMCID: PMC5341109.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Assessment of the red cell proteome of young patients with unexplained hemolytic anemia by two-dimensional differential in-gel electrophoresis (DIGE). PLoS One. 2012; 7(4):e34237.
von Löhneysen K, Scott TM, Soldau K, Xu X, Friedman JS. PMID: 22509282; PMCID: PMC3317954.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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A novel approach for in vivo measurement of mouse red cell redox status. Blood. 2011 Sep 29; 118(13):3694-7.
Xu X, von Löhneysen K, Soldau K, Noack D, Vu A, Friedman JS. PMID: 21832281; PMCID: PMC3186341.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events. J Exp Med. 2008 Feb 18; 205(2):373-83.
Mullick AE, Soldau K, Kiosses WB, Bell TA, Tobias PS, Curtiss LK. PMID: 18250194; PMCID: PMC2271019.
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74 Fields:
Translation:
AnimalsCells
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Double-stranded RNA-mediated TLR3 activation is enhanced by CD14. Immunity. 2006 Feb; 24(2):153-63.
Lee HK, Dunzendorfer S, Soldau K, Tobias PS. PMID: 16473828.
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72 Fields:
Translation:
HumansAnimalsCells
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Interaction of SP-A (surfactant protein A) with bacterial rough lipopolysaccharide (Re-LPS), and effects of SP-A on the binding of Re-LPS to CD14 and LPS-binding protein. Biochem J. 2005 Oct 01; 391(Pt 1):115-24.
García-Verdugo I, Sánchez-Barbero F, Soldau K, Tobias PS, Casals C. PMID: 15932345; PMCID: PMC1237145.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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TLR4 is the signaling but not the lipopolysaccharide uptake receptor. J Immunol. 2004 Jul 15; 173(2):1166-70.
Dunzendorfer S, Lee HK, Soldau K, Tobias PS. PMID: 15240706.
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PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
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Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: roles of LBP and sCD14 in mediating LPS responses. FASEB J. 2004 Jul; 18(10):1117-9.
Dunzendorfer S, Lee HK, Soldau K, Tobias PS. PMID: 15132988.
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44 Fields:
Translation:
HumansAnimalsCells
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Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2. J Biol Chem. 2001 Jun 15; 276(24):21129-35.
da Silva Correia J, Soldau K, Christen U, Tobias PS, Ulevitch RJ. PMID: 11274165.
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152 Fields:
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HumansAnimalsCells
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MD-2 binds to bacterial lipopolysaccharide. J Endotoxin Res. 2000; 6(6):489-91.
Viriyakosol S, Kirkland T, Soldau K, Tobias P. PMID: 11521076.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Innate immune system recognition of microbial pathogens. Immunol Res. 2000; 21(2-3):341-3.
Tobias PS, Lee H, Orr S, Soldau K, Tapping R. PMID: 10852135.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Membrane-anchored forms of lipopolysaccharide (LPS)-binding protein do not mediate cellular responses to LPS independently of CD14. J Immunol. 1999 May 01; 162(9):5483-9.
Tapping RI, Orr SL, Lawson EM, Soldau K, Tobias PS. PMID: 10228028.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Phagocytosis of gram-negative bacteria by a unique CD14-dependent mechanism. J Leukoc Biol. 1997 Dec; 62(6):786-94.
Schiff DE, Kline L, Soldau K, Lee JD, Pugin J, Tobias PS, Ulevitch RJ. PMID: 9400820.
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27 Fields:
Translation:
HumansCells
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Lipopolysaccharide (LPS)-binding proteins BPI and LBP form different types of complexes with LPS. J Biol Chem. 1997 Jul 25; 272(30):18682-5.
Tobias PS, Soldau K, Iovine NM, Elsbach P, Weiss J. PMID: 9228038.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14. J Biol Chem. 1995 May 05; 270(18):10482-8.
Tobias PS, Soldau K, Gegner JA, Mintz D, Ulevitch RJ. PMID: 7537731.
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PubMed Mentions:
80 Fields:
Translation:
HumansCells
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Cross-linking of lipopolysaccharide (LPS) to CD14 on THP-1 cells mediated by LPS-binding protein. J Immunol. 1993 Apr 01; 150(7):3011-21.
Tobias PS, Soldau K, Kline L, Lee JD, Kato K, Martin TP, Ulevitch RJ. PMID: 7681085.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein. J Biol Chem. 1989 Jun 25; 264(18):10867-71.
Tobias PS, Soldau K, Ulevitch RJ. PMID: 2471708.
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87 Fields:
Translation:
AnimalsCells
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Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum. J Exp Med. 1986 Sep 01; 164(3):777-93.
Tobias PS, Soldau K, Ulevitch RJ. PMID: 2427635; PMCID: PMC2188379.
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PubMed Mentions:
119 Fields:
Translation:
AnimalsCells
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Control of lipopolysaccharide-high-density lipoprotein interactions by an acute-phase reactant in human serum. Infect Immun. 1985 Oct; 50(1):73-6.
Tobias PS, McAdam KP, Soldau K, Ulevitch RJ. PMID: 2412965; PMCID: PMC262137.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells