Katrin Soldau

Title(s)	SRA 3, Pathology
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Multi-omic analysis of meningeal cerebral amyloid angiopathy reveals enrichment of unsubstituted glucosamine and extracellular proteins. J Neuropathol Exp Neurol. 2025 May 01; 84(5):398-411. Mayfield JE, Rajic AJ, Aguilar-Calvo P, Soldau K, Flores S, Lawrence R, Choudhury B, Ghassemian M, Pizzo DP, Wagner SL, Danque GA, Sumowski P, Hansen LA, Goodwill V, Esko JD, Sigurdson CJ. PMID: 40156913; PMCID: PMC12012350.

View in: PubMed Mentions: Fields:
Neu Neurology Pat Pathology
Translation:Humans
PrP C -induced signaling in human neurons activates phospholipase Cɣ1 and an Arc/Arg3.1 response. bioRxiv. 2025 Apr 05. Ojeda-Juarez D, Funk G, Richards E, Rajic AJ, McClatchy DB, Soldau K, Chen X, Yates JR, Gonias SL, Sigurdson CJ. PMID: 40236043; PMCID: PMC11996466.

View in: PubMed Mentions:
Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice. J Clin Invest. 2025 Apr 04. Lin J, Callender JA, Mayfield JE, McClatchy DB, Ojeda-Juárez D, Pourhamzeh M, Soldau K, Kurt TD, Danque GA, Khuu HK, Ronson JE, Pizzo DP, Du Y, Gruber MA, Sevillano AM, Wang J, Orrú CD, Chen J, Funk G, Aguilar-Calvo P, Aulston BD, Roy S, Rho JM, Bui JD, Newton AC, Lipton SA, Caughey B, Patrick GN, Doré K, Yates Iii JR, Sigurdson CJ. PMID: 40185484.

View in: PubMed Mentions: Fields:
Med Medicine (General)
Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice. J Clin Invest. 2025 Apr 04. Lin J, Callender JA, Mayfield JE, McClatchy DB, Ojeda-Juárez D, Pourhamzeh M, Soldau K, Kurt TD, Danque GA, Khuu HK, Ronson JE, Pizzo DP, Du Y, Gruber MA, Sevillano AM, Wang J, Orrú CD, Chen J, Funk G, Aguilar-Calvo P, Aulston BD, Roy S, Rho JM, Bui JD, Newton AC, Lipton SA, Caughey B, Patrick GN, Doré K, Yates Iii JR, Sigurdson CJ. PMID: 40185484.

View in: PubMed Mentions: Fields:
Med Medicine (General)
Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection. PLoS Pathog. 2023 09; 19(9):e1011487. Aguilar-Calvo P, Malik A, Sandoval DR, Barback C, Orrù CD, Standke HG, Thomas OR, Dwyer CA, Pizzo DP, Bapat J, Soldau K, Ogawa R, Riley MB, Nilsson KPR, Kraus A, Caughey B, Iliff JJ, Vera DR, Esko JD, Sigurdson CJ. PMID: 37747931; PMCID: PMC10586673.

View in: PubMed Mentions: 1 Fields:
Mic Microbiology
Translation:Animals Cells
Diminished Neuronal ESCRT-0 Function Exacerbates AMPA Receptor Derangement and Accelerates Prion-Induced Neurodegeneration. J Neurosci. 2023 05 24; 43(21):3970-3984. Lawrence JA, Aguilar-Calvo P, Ojeda-Juárez D, Khuu H, Soldau K, Pizzo DP, Wang J, Malik A, Shay TF, Sullivan EE, Aulston B, Song SM, Callender JA, Sanchez H, Geschwind MD, Roy S, Rissman RA, Trejo J, Tanaka N, Wu C, Chen X, Patrick GN, Sigurdson CJ. PMID: 37019623; PMCID: PMC10219035.

View in: PubMed Mentions: 5 Fields:
Neu Neurology
Translation:Humans Animals Cells
Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus. Neurobiol Dis. 2022 10 01; 172:105834. Ojeda-Juárez D, Lawrence JA, Soldau K, Pizzo DP, Wheeler E, Aguilar-Calvo P, Khuu H, Chen J, Malik A, Funk G, Nam P, Sanchez H, Geschwind MD, Wu C, Yeo GW, Chen X, Patrick GN, Sigurdson CJ. PMID: 35905927; PMCID: PMC10080886.

View in: PubMed Mentions: 3 Fields:
Neu Neurology
Translation:Animals
Minimal change prion retinopathy: Morphometric comparison of retinal and brain prion deposits in Creutzfeldt-Jakob disease. Exp Eye Res. 2022 09; 222:109172. Goodwill VS, Dryden I, Choi J, De Lillo C, Soldau K, Llibre-Guerra J, Sanchez H, Sigurdson CJ, Lin JH. PMID: 35803332; PMCID: PMC9946801.

View in: PubMed Mentions: 1 Fields:
Oph Ophthalmology
Translation:Humans
Metabolome Changes during In Vivo Red Cell Aging Reveal Disruption of Key Metabolic Pathways. iScience. 2020 Oct 23; 23(10):101630. Jamshidi N, Xu X, von Löhneysen K, Soldau K, Mohney RP, Karoly ED, Scott M, Friedman JS. PMID: 33103072; PMCID: PMC7575880.

View in: PubMed Mentions: 9
Prion protein post-translational modifications modulate heparan sulfate binding and limit aggregate size in prion disease. Neurobiol Dis. 2020 08; 142:104955. Callender JA, Sevillano AM, Soldau K, Kurt TD, Schumann T, Pizzo DP, Altmeppen H, Glatzel M, Esko JD, Sigurdson CJ. PMID: 32454127; PMCID: PMC7425694.

View in: PubMed Mentions: 4 Fields:
Neu Neurology
Translation:Animals Cells
Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease. J Clin Invest. 2020 03 02; 130(3):1350-1362. Sevillano AM, Aguilar-Calvo P, Kurt TD, Lawrence JA, Soldau K, Nam TH, Schumann T, Pizzo DP, Nyström S, Choudhury B, Altmeppen H, Esko JD, Glatzel M, Nilsson KPR, Sigurdson CJ. PMID: 31985492; PMCID: PMC7269597.

View in: PubMed Mentions: 24 Fields:
Med Medicine (General)
Translation:Animals Cells
Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions. Acta Neuropathol. 2020 03; 139(3):527-546. Aguilar-Calvo P, Sevillano AM, Bapat J, Soldau K, Sandoval DR, Altmeppen HC, Linsenmeier L, Pizzo DP, Geschwind MD, Sanchez H, Appleby BS, Cohen ML, Safar JG, Edland SD, Glatzel M, Nilsson KPR, Esko JD, Sigurdson CJ. PMID: 31673874; PMCID: PMC7036335.

View in: PubMed Mentions: 19 Fields:
Neu Neurology
Translation:Humans Animals
Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients. mBio. 2018 11 20; 9(6). Orrù CD, Soldau K, Cordano C, Llibre-Guerra J, Green AJ, Sanchez H, Groveman BR, Edland SD, Safar JG, Lin JH, Caughey B, Geschwind MD, Sigurdson CJ. PMID: 30459197; PMCID: PMC6247090.

View in: PubMed Mentions: 30 Fields:
Mic Microbiology
Generation of novel neuroinvasive prions following intravenous challenge. Brain Pathol. 2018 11; 28(6):999-1011. Aguilar-Calvo P, Bett C, Sevillano AM, Kurt TD, Lawrence J, Soldau K, Hammarström P, Nilsson KPR, Sigurdson CJ. PMID: 29505163; PMCID: PMC6123309.

View in: PubMed Mentions: 13 Fields:
Bra Brain Pat Pathology
Translation:Animals Cells
Post-translational modifications in PrP expand the conformational diversity of prions in vivo. Sci Rep. 2017 03 08; 7:43295. Aguilar-Calvo P, Xiao X, Bett C, Eraña H, Soldau K, Castilla J, Nilsson KP, Surewicz WK, Sigurdson CJ. PMID: 28272426; PMCID: PMC5341109.

View in: PubMed Mentions: 27 Fields:
Sci Science
Translation:Animals Cells
Assessment of the red cell proteome of young patients with unexplained hemolytic anemia by two-dimensional differential in-gel electrophoresis (DIGE). PLoS One. 2012; 7(4):e34237. von Löhneysen K, Scott TM, Soldau K, Xu X, Friedman JS. PMID: 22509282; PMCID: PMC3317954.

View in: PubMed Mentions: 5 Fields:
Med Medicine (General)Sci Science
Translation:Humans Cells
A novel approach for in vivo measurement of mouse red cell redox status. Blood. 2011 Sep 29; 118(13):3694-7. Xu X, von Löhneysen K, Soldau K, Noack D, Vu A, Friedman JS. PMID: 21832281; PMCID: PMC3186341.

View in: PubMed Mentions: 7 Fields:
Hem Hematology
Translation:Animals Cells
Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events. J Exp Med. 2008 Feb 18; 205(2):373-83. Mullick AE, Soldau K, Kiosses WB, Bell TA, Tobias PS, Curtiss LK. PMID: 18250194; PMCID: PMC2271019.

View in: PubMed Mentions: 76 Fields:
All Allergy and Immunology Med Medicine (General)
Translation:Animals Cells
Double-stranded RNA-mediated TLR3 activation is enhanced by CD14. Immunity. 2006 Feb; 24(2):153-63. Lee HK, Dunzendorfer S, Soldau K, Tobias PS. PMID: 16473828.

View in: PubMed Mentions: 65 Fields:
All Allergy and Immunology
Translation:Humans Animals Cells
Interaction of SP-A (surfactant protein A) with bacterial rough lipopolysaccharide (Re-LPS), and effects of SP-A on the binding of Re-LPS to CD14 and LPS-binding protein. Biochem J. 2005 Oct 01; 391(Pt 1):115-24. García-Verdugo I, Sánchez-Barbero F, Soldau K, Tobias PS, Casals C. PMID: 15932345; PMCID: PMC1237145.

View in: PubMed Mentions: 14 Fields:
Bio Biochemistry
Translation:Humans Cells
TLR4 is the signaling but not the lipopolysaccharide uptake receptor. J Immunol. 2004 Jul 15; 173(2):1166-70. Dunzendorfer S, Lee HK, Soldau K, Tobias PS. PMID: 15240706.

View in: PubMed Mentions: 57 Fields:
All Allergy and Immunology
Translation:Animals Cells
Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: roles of LBP and sCD14 in mediating LPS responses. FASEB J. 2004 Jul; 18(10):1117-9. Dunzendorfer S, Lee HK, Soldau K, Tobias PS. PMID: 15132988.

View in: PubMed Mentions: 44 Fields:
Bio Biology Phy Physiology
Translation:Humans Animals Cells
Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2. J Biol Chem. 2001 Jun 15; 276(24):21129-35. da Silva Correia J, Soldau K, Christen U, Tobias PS, Ulevitch RJ. PMID: 11274165.

View in: PubMed Mentions: 158 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Innate immune system recognition of microbial pathogens. Immunol Res. 2000; 21(2-3):341-3. Tobias PS, Lee H, Orr S, Soldau K, Tapping R. PMID: 10852135.

View in: PubMed Mentions: 2 Fields:
All Allergy and Immunology
Translation:Humans
MD-2 binds to bacterial lipopolysaccharide. J Endotoxin Res. 2000; 6(6):489-91. Viriyakosol S, Kirkland T, Soldau K, Tobias P. PMID: 11521076.

View in: PubMed Mentions: 8 Fields:
Bac Bacteriology Vas Vascular Diseases
Translation:Humans Animals Cells
Membrane-anchored forms of lipopolysaccharide (LPS)-binding protein do not mediate cellular responses to LPS independently of CD14. J Immunol. 1999 May 01; 162(9):5483-9. Tapping RI, Orr SL, Lawson EM, Soldau K, Tobias PS. PMID: 10228028.

View in: PubMed Mentions: 2 Fields:
All Allergy and Immunology
Translation:Humans Animals Cells
Phagocytosis of gram-negative bacteria by a unique CD14-dependent mechanism. J Leukoc Biol. 1997 Dec; 62(6):786-94. Schiff DE, Kline L, Soldau K, Lee JD, Pugin J, Tobias PS, Ulevitch RJ. PMID: 9400820.

View in: PubMed Mentions: 28 Fields:
All Allergy and Immunology
Translation:Humans Cells
Lipopolysaccharide (LPS)-binding proteins BPI and LBP form different types of complexes with LPS. J Biol Chem. 1997 Jul 25; 272(30):18682-5. Tobias PS, Soldau K, Iovine NM, Elsbach P, Weiss J. PMID: 9228038.

View in: PubMed Mentions: 25 Fields:
Bio Biochemistry
Translation:Humans Cells
Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14. J Biol Chem. 1995 May 05; 270(18):10482-8. Tobias PS, Soldau K, Gegner JA, Mintz D, Ulevitch RJ. PMID: 7537731.

View in: PubMed Mentions: 79 Fields:
Bio Biochemistry
Translation:Humans Cells
Cross-linking of lipopolysaccharide (LPS) to CD14 on THP-1 cells mediated by LPS-binding protein. J Immunol. 1993 Apr 01; 150(7):3011-21. Tobias PS, Soldau K, Kline L, Lee JD, Kato K, Martin TP, Ulevitch RJ. PMID: 7681085.

View in: PubMed Mentions: 32 Fields:
All Allergy and Immunology
Translation:Humans Animals Cells
Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein. J Biol Chem. 1989 Jun 25; 264(18):10867-71. Tobias PS, Soldau K, Ulevitch RJ. PMID: 2471708.

View in: PubMed Mentions: 90 Fields:
Bio Biochemistry
Translation:Animals Cells
Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum. J Exp Med. 1986 Sep 01; 164(3):777-93. Tobias PS, Soldau K, Ulevitch RJ. PMID: 2427635; PMCID: PMC2188379.

View in: PubMed Mentions: 121 Fields:
All Allergy and Immunology Med Medicine (General)
Translation:Animals Cells
Control of lipopolysaccharide-high-density lipoprotein interactions by an acute-phase reactant in human serum. Infect Immun. 1985 Oct; 50(1):73-6. Tobias PS, McAdam KP, Soldau K, Ulevitch RJ. PMID: 2412965; PMCID: PMC262137.

View in: PubMed Mentions: 17 Fields:
All Allergy and Immunology Com Communicable Diseases
Translation:Humans Cells