Seema Aceves

Title(s)Professor Of Clinical, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    UC San DiegoMD, PhDMedical Scientist Training Program

    Collapse Overview 
    Collapse Overview
    Dr. Aceves completed both her medical degree and her PhD through the Medical Scientist Training Program at UC San Diego. She also completed her pediatric internship, residency and a fellowship in allergy and immunology at UC San Diego.

    Dr. Aceves was named a Physician of Exceptional Excellence in the 2012 "San Diego's Top Doctors" survey from the San Diego County Medical Society and San Diego Magazine.

    She was elected to the American Society for Clinical Investigation in 2013.

    Collapse Research 
    Collapse Research Activities and Funding
    Probing the Mechanisms of Fibroblast-Extracellular Matrix Interactions to Assess Disease Severity in Allergic Eosinophilic Esophagitis
    NIH R21AI154353May 22, 2020 - Apr 30, 2022
    Role: Principal Investigator
    LIGHT/TNFSF14 in allergic esophagitis remodeling
    NIH R01DK114457Apr 1, 2018 - Feb 28, 2022
    Role: Co-Principal Investigator
    Mentoring Patient Oriented Research in Allergic Eosinophilic Gastrointestinal Disorders
    NIH K24AI135034Dec 12, 2017 - Nov 30, 2022
    Role: Principal Investigator
    Consortium of Eosinophilic Gastrointestinal Disease Researchers
    NIH U54AI117804Aug 15, 2014 - Jul 31, 2019
    Role: Co-Investigator
    Contribution of rigid matrix to allergic eosinophilic esophagitis pathogenesis
    NIH R01AI092135Jul 1, 2011 - Jun 30, 2021
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mechanotransduction Induced Interplay between Phospholamban and Yes Activated Protein Induces Smooth Muscle Cell Hypertrophy. Mucosal Immunol. 2024 Feb 27. Rawson R, Duong L, Tkachenko E, Chiang AWT, Okamoto K, Dohil R, Lewis NE, Kurten R, Abud EM, Aceves SS. PMID: 38423390.
      View in: PubMed   Mentions:    Fields:    
    2. Eosinophilic esophagitis: Shifting immune complexity beyond the eosinophil. J Allergy Clin Immunol. 2024 Mar; 153(3):669-671. Lewis NE, Aceves SS. PMID: 38262501.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Pathophysiology and Clinical Impact of Esophageal Remodeling and Fibrosis in Eosinophilic Esophagitis. Immunol Allergy Clin North Am. 2024 May; 44(2):129-143. Menard-Katcher C, Aceves S. PMID: 38575213.
      View in: PubMed   Mentions:    Fields:    
    4. Sleep, anxiety, somatization, quality of life, and resilience in pediatric patients with eosinophilic esophagitis. Clin Transl Gastroenterol. 2024 Jan 11. Jensen ET, Chaiboonma K, Ayala O, Proia A, Aceves SS. PMID: 38205930.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Concepts and Controversies in Eosinophilic Esophagitis: What's Coming Down the Pipe? Gastroenterology. 2024 Mar; 166(3):382-395. Peterson K, Collins MH, Aceves SS, Chehade M, Gonsalves N. PMID: 38052335.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. The Index of Severity for Eosinophilic Esophagitis (I-SEE) Reflects Longitudinal Clinicopathologic Changes in Children. Clin Gastroenterol Hepatol. 2024 Apr; 22(4):732-740.e1. Dickerson A, Kolemen A, Kime K, Chaiboonma K, Dohil R, Furuta GT, Dellon ES, Aceves SS. PMID: 37743034.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Ascending to New Heights for Novel Therapeutics for Eosinophilic Esophagitis. Gastroenterology. 2024 Jan; 166(1):1-10. Hirano I, Dellon ES, Falk GW, Gonsalves NP, Furuta GT, Bredenoord AJ, ASCENT WORKING GROUP. PMID: 37690772; PMCID: PMC10872872.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Breakthroughs in understanding and treating eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERs Symposium at the 2022 American Academy of Allergy, Asthma & Immunology Meeting. J Allergy Clin Immunol. 2023 12; 152(6):1382-1393. Chehade M, Wright BL, Atkins D, Aceves SS, Ackerman SJ, Assa'ad AH, Bauer M, Collins MH, Commins SP, Davis CM, Dellon ES, Doerfler B, Gleich GJ, Gupta SK, Hill DA, Jensen ET, Katzka D, Kliewer K, Kodroff E, Kottyan LC, Kyle S, Muir AB, Pesek RD, Peterson K, Shreffler WG, Spergel JM, Strobel MJ, Wechsler J, Zimmermann N, Furuta GT, Rothenberg ME. PMID: 37660987.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Enhancing diversity, equity, inclusion, and accessibility in eosinophilic gastrointestinal disease research: the consortium for eosinophilic gastrointestinal disease researchers' journey. Ther Adv Rare Dis. 2023 Jan-Dec; 4:26330040231180895. Chehade M, Furuta G, Klion A, Abonia JP, Aceves S, Bose P, Collins MH, Davis C, Dellon ES, Eickel G, Falk G, Gupta S, Hiremath G, Howard A, Jensen ET, Kesh S, Khoury P, Kocher K, Kodroff E, Kyle S, Mak N, McCoy D, Mehta P, Menard-Katcher P, Mukkada V, Paliana A, Rothenberg M, Sable K, Schmitt C, Scott M, Spergel J, Strobel MJ, Wechsler JB, Yang GY, Zicarelli A, Muir AB, Wright BL, Bailey DD. PMID: 37588777; PMCID: PMC10426297.
      View in: PubMed   Mentions: 1  
    10. Prospective study of an amino acid-based elemental diet in an eosinophilic gastritis and gastroenteritis nutrition trial. J Allergy Clin Immunol. 2023 09; 152(3):676-688. Gonsalves N, Doerfler B, Zalewski A, Yang GY, Martin LJ, Zhang X, Shoda T, Brusilovsky M, Aceves S, Thompson K, Rudman Spergel AK, Furuta G, Rothenberg ME, Hirano I. PMID: 37462600; PMCID: PMC10528593.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. A Newly Proposed Severity Index for Eosinophilic Esophagitis is Associated With Baseline Clinical Features and Successful Treatment Response. Clin Gastroenterol Hepatol. 2023 09; 21(10):2534-2542.e1. Cotton CC, Moist SE, McGee SJ, Furuta GT, Aceves SS, Dellon ES. PMID: 37061110; PMCID: PMC10524581.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Development and Validation of the Veterans Affairs Eosinophilic Esophagitis Cohort. Clin Gastroenterol Hepatol. 2023 11; 21(12):3030-3040.e4. Low EE, Song Q, Yadlapati R, Dellon ES, Aceves S, Liu L, Gupta S, Choksi YA, Shah SC. PMID: 37031716; PMCID: PMC10558623.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Esophageal Epithelium and Lamina Propria Are Unevenly Involved in Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2023 10; 21(11):2807-2816.e3. Hiremath G, Sun L, Collins MH, Bonis PA, Arva NC, Capocelli KE, Chehade M, Davis CM, Falk GW, Gonsalves N, Gupta SK, Hirano I, Leung J, Khoury P, Mukkada VA, Martin LJ, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME, Koyama T, Dellon ES. PMID: 36967100; PMCID: PMC10518022.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. One-food versus six-food elimination diet therapy for the treatment of eosinophilic oesophagitis: a multicentre, randomised, open-label trial. Lancet Gastroenterol Hepatol. 2023 05; 8(5):408-421. Kliewer KL, Gonsalves N, Dellon ES, Katzka DA, Abonia JP, Aceves SS, Arva NC, Besse JA, Bonis PA, Caldwell JM, Capocelli KE, Chehade M, Cianferoni A, Collins MH, Falk GW, Gupta SK, Hirano I, Krischer JP, Leung J, Martin LJ, Menard-Katcher P, Mukkada VA, Peterson KA, Shoda T, Rudman Spergel AK, Spergel JM, Yang GY, Zhang X, Furuta GT, Rothenberg ME. PMID: 36863390; PMCID: PMC10102869.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    15. Monitoring Patients With Eosinophilic Esophagitis in Routine Clinical Practice - International Expert Recommendations. Clin Gastroenterol Hepatol. 2023 09; 21(10):2526-2533. Arnim UV, Biedermann L, Aceves SS, Bonis PA, Collins MH, Dellon ES, Furuta GT, Gonsalves N, Gupta S, Hirano I, Lucendo AJ, Miehlke S, Oliva S, Schlag C, Schoepfer A, Straumann A, Vieth M, Bredenoord AJ, EUREOS and TIGERs. PMID: 36572109.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    16. Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis. N Engl J Med. 2022 12 22; 387(25):2317-2330. Dellon ES, Rothenberg ME, Collins MH, Hirano I, Chehade M, Bredenoord AJ, Lucendo AJ, Spergel JM, Aceves S, Sun X, Kosloski MP, Kamal MA, Hamilton JD, Beazley B, McCann E, Patel K, Mannent LP, Laws E, Akinlade B, Amin N, Lim WK, Wipperman MF, Ruddy M, Patel N, Weinreich DR, Yancopoulos GD, Shumel B, Maloney J, Giannelou A, Shabbir A. PMID: 36546624.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCTClinical Trials
    17. Mucosal Microbiota Associated With Eosinophilic Esophagitis and Eosinophilic Gastritis. J Pediatr Gastroenterol Nutr. 2023 03 01; 76(3):347-354. Furuta GT, Fillon SA, Williamson KM, Robertson CE, Stevens MJ, Aceves SS, Arva NC, Chehade M, Collins MH, Davis CM, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Leung J, Martin LJ, Menard-Katcher P, Mukkada VA, Peterson K, Spergel JM, Wechsler JB, Yang GY, Rothenberg ME, Harris JK. PMID: 36525669; PMCID: PMC10201396.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Clinical guidance for the use of dupilumab in eosinophilic esophagitis: A yardstick. Ann Allergy Asthma Immunol. 2023 03; 130(3):371-378. Aceves SS, Dellon ES, Greenhawt M, Hirano I, Liacouras CA, Spergel JM. PMID: 36521784.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    19. A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis. J Immunol. 2022 Oct 26. Manresa MC, Miki H, Miller J, Okamoto K, Dobaczewska K, Herro R, Gupta RK, Kurten R, Aceves SS, Croft M. PMID: 36426994.
      View in: PubMed   Mentions: 1     Fields:    
    20. A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis. J Immunol. 2022 Oct 26. Manresa MC, Miki H, Miller J, Okamoto K, Dobaczewska K, Herro R, Gupta RK, Kurten R, Aceves SS, Croft M. PMID: 36288906; PMCID: PMC10130236.
      View in: PubMed   Mentions: 4     Fields:    
    21. Current state of biologics in treating eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2023 01; 130(1):15-20. Nhu QM, Aceves SS. PMID: 36243282.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. Reply. Gastroenterology. 2022 Dec; 163(6):1720-1721. Dellon ES, Collins MH, Furuta GT, Aceves SS. PMID: 36063963.
      View in: PubMed   Mentions:    Fields:    
    23. Endoscopic approach to eosinophilic esophagitis: American Society for Gastrointestinal Endoscopy Consensus Conference. Gastrointest Endosc. 2022 10; 96(4):576-592.e1. Aceves SS, Alexander JA, Baron TH, Bredenoord AJ, Day L, Dellon ES, Falk GW, Furuta GT, Gonsalves N, Hirano I, Konda VJA, Lucendo AJ, Moawad F, Peterson KA, Putnam PE, Richter J, Schoepfer AM, Straumann A, McBride DL, Sharma P, Katzka DA. PMID: 35965102.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    24. A subset of patients with eosinophilic esophagitis demonstrate delayed gastric emptying. J Allergy Clin Immunol Pract. 2022 10; 10(10):2764-2767.e1. Khosh-Hemmat E, Babbel J, Chaiboonma K, Dohil R, Aceves SS. PMID: 35779782.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Eosinophilic gastrointestinal diseases make a name for themselves: A new consensus statement with updated nomenclature. J Allergy Clin Immunol. 2022 08; 150(2):291-293. Wright BL, Schwartz JT, Ruffner MA, Furuta GT, Gonsalves N, Dellon ES, Aceves SS. PMID: 35649464; PMCID: PMC9378528.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    26. A Clinical Severity Index for Eosinophilic Esophagitis: Development, Consensus, and Future Directions. J Allergy Clin Immunol. 2022 07; 150(1):33-47. Dellon ES, Khoury P, Muir AB, Liacouras CA, Safroneeva E, Atkins D, Collins MH, Gonsalves N, Falk GW, Spergel JM, Hirano I, Chehade M, Schoepfer AM, Menard-Katcher C, Katzka DA, Bonis PA, Bredenoord AJ, Geng B, Jensen ET, Pesek RD, Feuerstadt P, Gupta SK, Lucendo AJ, Genta RM, Hiremath G, McGowan EC, Moawad FJ, Peterson KA, Rothenberg ME, Straumann A, Furuta GT, Aceves SS. PMID: 35606166; PMCID: PMC9549868.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. A Clinical Severity Index for Eosinophilic Esophagitis: Development, Consensus, and Future Directions. Gastroenterology. 2022 07; 163(1):59-76. Dellon ES, Khoury P, Muir AB, Liacouras CA, Safroneeva E, Atkins D, Collins MH, Gonsalves N, Falk GW, Spergel JM, Hirano I, Chehade M, Schoepfer AM, Menard-Katcher C, Katzka DA, Bonis PA, Bredenoord AJ, Geng B, Jensen ET, Pesek RD, Feuerstadt P, Gupta SK, Lucendo AJ, Genta RM, Hiremath G, McGowan EC, Moawad FJ, Peterson KA, Rothenberg ME, Straumann A, Furuta GT, Aceves SS. PMID: 35606197; PMCID: PMC9233087.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    28. Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature. J Pediatr Gastroenterol Nutr. 2022 06 01; 74(6):e160-e161. Bose P, Chang JW, Dellon ES, Furuta GT, Aceves SS, Gonsalves N. PMID: 35442234.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Disease Burden and Unmet Need in Eosinophilic Esophagitis. Am J Gastroenterol. 2022 08 01; 117(8):1231-1241. Bredenoord AJ, Patel K, Schoepfer AM, Dellon ES, Chehade M, Aceves SS, Spergel JM, Shumel B, Deniz Y, Rowe PJ, Jacob-Nara JA. PMID: 35417421.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    30. Mast cell-pain connection in eosinophilic esophagitis. Allergy. 2022 06; 77(6):1895-1899. Zhang S, Shoda T, Aceves SS, Arva NC, Chehade M, Collins MH, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Leung J, Spergel AKR, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Rothenberg ME, Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Investigators Group. PMID: 35175645; PMCID: PMC9167217.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    31. Prospective Endoscopic Activity Assessment for Eosinophilic Gastritis in a Multisite Cohort. Am J Gastroenterol. 2022 03 01; 117(3):413-423. Hirano I, Collins MH, King E, Sun Q, Chehade M, Abonia JP, Bonis PA, Capocelli KE, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Leung J, Katzka D, Menard-Katcher P, Khoury P, Klion A, Mukkada VA, Peterson K, Shoda T, Rudman-Spergel AK, Spergel JA, Yang GY, Rothenberg ME, Aceves SS, Furuta GT, CEGIR investigators. PMID: 35080202; PMCID: PMC8897269.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    32. International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature. Clin Gastroenterol Hepatol. 2022 11; 20(11):2474-2484.e3. Dellon ES, Gonsalves N, Abonia JP, Alexander JA, Arva NC, Atkins D, Attwood SE, Auth MKH, Bailey DD, Biederman L, Blanchard C, Bonis PA, Bose P, Bredenoord AJ, Chang JW, Chehade M, Collins MH, Di Lorenzo C, Dias JA, Dohil R, Dupont C, Falk GW, Ferreira CT, Fox AT, Genta RM, Greuter T, Gupta SK, Hirano I, Hiremath GS, Horsley-Silva JL, Ishihara S, Ishimura N, Jensen ET, Gutiérrez-Junquera C, Katzka DA, Khoury P, Kinoshita Y, Kliewer KL, Koletzko S, Leung J, Liacouras CA, Lucendo AJ, Martin LJ, McGowan EC, Menard-Katcher C, Metz DC, Miller TL, Moawad FJ, Muir AB, Mukkada VA, Murch S, Nhu QM, Nomura I, Nurko S, Ohtsuka Y, Oliva S, Orel R, Papadopoulou A, Patel DA, Pesek RD, Peterson KA, Philpott H, Putnam PE, Richter JE, Rosen R, Ruffner MA, Safroneeva E, Schreiner P, Schoepfer A, Schroeder SR, Shah N, Souza RF, Spechler SJ, Spergel JM, Straumann A, Talley NJ, Thapar N, Vandenplas Y, Venkatesh RD, Vieira MC, von Arnim U, Walker MM, Wechsler JB, Wershil BK, Wright BL, Yamada Y, Yang GY, Zevit N, Rothenberg ME, Furuta GT, Aceves SS. PMID: 35181570; PMCID: PMC9378753.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    33. Development and Validation of Web-Based Tool to Predict Lamina Propria Fibrosis in Eosinophilic Esophagitis. Am J Gastroenterol. 2022 02 01; 117(2):272-279. Hiremath G, Sun L, Correa H, Acra S, Collins MH, Bonis P, Arva NC, Capocelli KE, Falk GW, King E, Gonsalves N, Gupta SK, Hirano I, Mukkada VA, Martin LJ, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME, Koyama T, Dellon ES. PMID: 34932022; PMCID: PMC8858426.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    34. Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study. Gastroenterology. 2022 05; 162(6):1635-1649. Shoda T, Collins MH, Rochman M, Wen T, Caldwell JM, Mack LE, Osswald GA, Besse JA, Haberman Y, Aceves SS, Arva NC, Capocelli KE, Chehade M, Davis CM, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Klion A, Menard-Katcher C, Leung J, Mukkada VA, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Denson LA, Rothenberg ME, Consortium of Eosinophilic Gastrointestinal Diseases Researchers (CEGIR). PMID: 35085569; PMCID: PMC9038694.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    35. Impressions and aspirations from the FDA GREAT VI Workshop on Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis and Perspectives for Progress in the Field. J Allergy Clin Immunol. 2022 03; 149(3):844-853. Rothenberg ME, Hottinger SKB, Gonsalves N, Furuta GT, Collins MH, Talley NJ, Peterson K, Menard-Katcher C, Smith M, Hirano I, Genta RM, Chehade M, Gupta SK, Spergel JM, Aceves SS, Dellon ES. PMID: 34953790; PMCID: PMC8901475.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    36. LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms. Mucosal Immunol. 2022 02; 15(2):327-337. Manresa MC, Wu A, Nhu QM, Chiang AWT, Okamoto K, Miki H, Kurten R, Pham E, Duong LD, Lewis NE, Akuthota P, Croft M, Aceves SS. PMID: 34903876; PMCID: PMC8866113.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    37. Noninvasive tests for eosinophilic esophagitis: Ready for use? Ann Allergy Asthma Immunol. 2022 07; 129(1):27-34. McGowan EC, Aceves SS. PMID: 34706258; PMCID: PMC9035192.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    38. Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk. Gastroenterology. 2022 02; 162(2):439-453. Shoda T, Wen T, Caldwell JM, Ben-Baruch Morgenstern N, Osswald GA, Rochman M, Mack LE, Felton JM, Abonia JP, Arva NC, Atkins D, Bonis PA, Capocelli KE, Collins MH, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Leung J, Menard-Katcher PA, Mukkada VA, Putnam PE, Rudman Spergel AK, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME, Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Investigators Group. PMID: 34687736; PMCID: PMC8792211.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    39. A genome-wide association meta-analysis identifies new eosinophilic esophagitis loci. J Allergy Clin Immunol. 2022 03; 149(3):988-998. Chang X, March M, Mentch F, Nguyen K, Glessner J, Qu H, Liu Y, Furuta G, Aceves S, Gonsalves N, Nadeau K, Cianferoni A, Spergel J, Sleiman P, Hakonarson H. PMID: 34506852; PMCID: PMC9579995.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    40. Treatment of Eosinophilic Esophagitis: Diet or Medication? J Allergy Clin Immunol Pract. 2021 09; 9(9):3249-3256. Chehade M, Aceves SS. PMID: 34507706.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    41. Onset of eosinophilic esophagitis during a clinical trial program of oral immunotherapy for peanut allergy. J Allergy Clin Immunol Pract. 2021 12; 9(12):4496-4501. Nilsson C, Scurlock AM, Dellon ES, Brostoff JM, Pham T, Ryan R, Brown KR, Adelman DC, Aceves SS. PMID: 34389504.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    42. Development of a core outcome set for therapeutic studies in eosinophilic esophagitis (COREOS). J Allergy Clin Immunol. 2022 02; 149(2):659-670. COREOS Collaborators:, Ma C, Schoepfer AM, Dellon ES, Bredenoord AJ, Chehade M, Collins MH, Feagan BG, Furuta GT, Gupta SK, Hirano I, Jairath V, Katzka DA, Pai RK, Rothenberg ME, Straumann A, Aceves SS, Alexander JA, Arva NC, Atkins D, Biedermann L, Blanchard C, Cianferoni A, Ciriza de Los Rios C, Clayton F, Davis CM, de Bortoli N, Dias JA, Falk GW, Genta RM, Ghaffari G, Gonsalves N, Greuter T, Hopp R, Hsu Blatman KS, Jensen ET, Johnston D, Kagalwalla AF, Larsson HM, Leung J, Louis H, Masterson JC, Menard-Katcher C, Menard-Katcher PA, Moawad FJ, Muir AB, Mukkada VA, Penagini R, Pesek RD, Peterson K, Putnam PE, Ravelli A, Savarino EV, Schlag C, Schreiner P, Simon D, Smyrk TC, Spergel JM, Taft TH, Terreehorst I, Vanuytsel T, Venter C, Vieira MC, Vieth M, Vlieg-Boerstra B, von Arnim U, Walker MM, Wechsler JB, Woodland P, Woosley JT, Yang GY, Zevit N, Safroneeva E. PMID: 34242635; PMCID: PMC8733049.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    43. The role of the allergist in the management of eosinophilic esophagitis. Curr Opin Gastroenterol. 2021 07 01; 37(4):390-396. Woo W, Aceves SS. PMID: 34059605; PMCID: PMC8527848.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    44. Long-Lasting Dissociation of Esophageal Eosinophilia and Symptoms After Dilation in Adults With Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2022 04; 20(4):766-775.e4. Safroneeva E, Pan Z, King E, Martin LJ, Collins MH, Yang GY, Capocelli KE, Arva NC, Abonia JP, Atkins D, Bonis PA, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Leung J, Menard-Katcher PA, Mukkada VA, Schoepfer AM, Spergel JM, Wershil BK, Rothenberg ME, Aceves SS, Furuta GT, Consortium of Eosinophilic Gastrointestinal Disease Researchers. PMID: 34062314; PMCID: PMC8628021.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    45. Type 2 Immunity and Age Modify Gene Expression of Coronavirus-induced Disease 2019 Receptors in Eosinophilic Gastrointestinal Disorders. J Pediatr Gastroenterol Nutr. 2021 05 01; 72(5):718-722. Chiang AWT, Duong LD, Shoda T, Nhu QM, Ruffner M, Hara T, Aaron B, Joplin E, Manresa MC, Abonia JP, Dellon ES, Hirano I, Gonsalves N, Gupta SK, Furuta GT, Rothenberg ME, Lewis NE, Muir AB, Aceves SS, CEGIR Investigator Group. PMID: 33394891; PMCID: PMC8048378.
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    50. Increased Production of LIGHT by T Cells in Eosinophilic Esophagitis Promotes Differentiation of Esophageal Fibroblasts Toward an Inflammatory Phenotype. Gastroenterology. 2020 11; 159(5):1778-1792.e13. Manresa MC, Chiang AWT, Kurten RC, Dohil R, Brickner H, Dohil L, Herro R, Akuthota P, Lewis NE, Croft M, Aceves SS. PMID: 32712105; PMCID: PMC7726704.
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    56. Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids. Curr Protoc Stem Cell Biol. 2020 03; 52(1):e106. Nakagawa H, Kasagi Y, Karakasheva TA, Hara T, Aaron B, Shimonosono M, Kijima T, Giroux V, Bailey D, Wilkins B, Abrams JA, Falk GW, Aceves SS, Spergel JM, Hamilton KE, Whelan KA, Muir AB. PMID: 32105412; PMCID: PMC7288850.
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    58. The potential for malignancy from atopic disorders and allergic inflammation: A systematic review and meta-analysis. Clin Exp Allergy. 2020 02; 50(2):147-159. Muir AB, Whelan KA, Dougherty MK, Aaron B, Navarre B, Aceves SS, Dellon ES, Jensen ET. PMID: 31743536; PMCID: PMC6994341.
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    60. Use of hPSC-derived 3D organoids and mouse genetics to define the roles of YAP in the development of the esophagus. Development. 2019 12 04; 146(23). Bailey DD, Zhang Y, van Soldt BJ, Jiang M, Suresh S, Nakagawa H, Rustgi AK, Aceves SS, Cardoso WV, Que J. PMID: 31748205; PMCID: PMC6918786.
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    68. Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. Sci Rep. 2019 04 17; 9(1):6206. Kurten RC, Rawson R, Shoda T, Duong LD, Adejumobi D, Levy R, Newbury RO, Rothenberg ME, Akuthota P, Wright BL, Dohil R, Jones SM, Aceves SS. PMID: 30996235; PMCID: PMC6470157.
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    98. How do gastroenterologists assess overall activity of eosinophilic esophagitis in adult patients? Am J Gastroenterol. 2015 Mar; 110(3):402-14. Schoepfer AM, Panczak R, Zwahlen M, Kuehni CE, Coslovsky M, Maurer E, Haas NA, Alexander JA, Dellon ES, Gonsalves N, Hirano I, Leung J, Bussmann C, Collins MH, Newbury RO, De Petris G, Smyrk TC, Woosley JT, Yan P, Yang GY, Romero Y, Katzka DA, Furuta GT, Gupta SK, Aceves SS, Chehade M, Blanchard C, Straumann A, Safroneeva E, International EEsAI Study Group. PMID: 25732414.
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    99. Reply: To PMID 24035776. Clin Gastroenterol Hepatol. 2015 May; 13(5):1030. Aceves SS. PMID: 25737444.
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    100. Food allergy and eosinophilic esophagitis: what do we do? J Allergy Clin Immunol Pract. 2015 Jan-Feb; 3(1):25-32. Chehade M, Aceves SS, Furuta GT, Fleischer DM. PMID: 25577614.
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    101. Eosinophilic esophagitis. Immunol Allergy Clin North Am. 2015 Feb; 35(1):145-59. Aceves SS. PMID: 25459582.
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    102. GWAS identifies four novel eosinophilic esophagitis loci. Nat Commun. 2014 Nov 19; 5:5593. Sleiman PM, Wang ML, Cianferoni A, Aceves S, Gonsalves N, Nadeau K, Bredenoord AJ, Furuta GT, Spergel JM, Hakonarson H. PMID: 25407941; PMCID: PMC4238044.
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    103. Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signaling. J Mol Cell Cardiol. 2015 Feb; 79:133-44. Banerjee I, Carrion K, Serrano R, Dyo J, Sasik R, Lund S, Willems E, Aceves S, Meili R, Mercola M, Chen J, Zambon A, Hardiman G, Doherty TA, Lange S, del Álamo JC, Nigam V. PMID: 25446186; PMCID: PMC4302020.
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    104. Transcriptome analysis of proton pump inhibitor-responsive esophageal eosinophilia reveals proton pump inhibitor-reversible allergic inflammation. J Allergy Clin Immunol. 2015 Jan; 135(1):187-97. Wen T, Dellon ES, Moawad FJ, Furuta GT, Aceves SS, Rothenberg ME. PMID: 25441638; PMCID: PMC4289084.
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    105. Health-related quality of life over time in children with eosinophilic esophagitis and their families. J Pediatr Gastroenterol Nutr. 2014 Sep; 59(3):308-16. Klinnert MD, Silveira L, Harris R, Moore W, Atkins D, Fleischer DM, Menard-Katcher C, Aceves S, Spergel JM, Franciosi JP, Furuta GT. PMID: 24897164; PMCID: PMC4141021.
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    106. Food allergy: a practice parameter update-2014. J Allergy Clin Immunol. 2014 Nov; 134(5):1016-25.e43. Sampson HA, Aceves S, Bock SA, James J, Jones S, Lang D, Nadeau K, Nowak-Wegrzyn A, Oppenheimer J, Perry TT, Randolph C, Sicherer SH, Simon RA, Vickery BP, Wood R, Joint Task Force on Practice Parameters, Bernstein D, Blessing-Moore J, Khan D, Lang D, Nicklas R, Oppenheimer J, Portnoy J, Randolph C, Schuller D, Spector S, Tilles SA, Wallace D, Practice Parameter Workgroup, Sampson HA, Aceves S, Bock SA, James J, Jones S, Lang D, Nadeau K, Nowak-Wegrzyn A, Oppenheimer J, Perry TT, Randolph C, Sicherer SH, Simon RA, Vickery BP, Wood R. PMID: 25174862.
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    107. Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis. Gastroenterology. 2014 Dec; 147(6):1255-66.e21. Schoepfer AM, Straumann A, Panczak R, Coslovsky M, Kuehni CE, Maurer E, Haas NA, Romero Y, Hirano I, Alexander JA, Gonsalves N, Furuta GT, Dellon ES, Leung J, Collins MH, Bussmann C, Netzer P, Gupta SK, Aceves SS, Chehade M, Moawad FJ, Enders FT, Yost KJ, Taft TH, Kern E, Zwahlen M, Safroneeva E, International Eosinophilic Esophagitis Activity Index Study Group. PMID: 25160980; PMCID: PMC4425255.
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    108. Smad3-deficient mice have reduced esophageal fibrosis and angiogenesis in a model of egg-induced eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2014 Jul; 59(1):10-6. Cho JY, Doshi A, Rosenthal P, Beppu A, Miller M, Aceves S, Broide D. PMID: 24590208; PMCID: PMC4148477.
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    109. Food and aeroallergens in eosinophilic esophagitis: role of the allergist in patient management. Curr Opin Gastroenterol. 2014 Jul; 30(4):391-5. Aceves SS. PMID: 24867155; PMCID: PMC4309387.
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    110. TGF-β1-induced phospholamban expression alters esophageal smooth muscle cell contraction in patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2014 Nov; 134(5):1100-1107.e4. Beppu LY, Anilkumar AA, Newbury RO, Dohil R, Broide DH, Aceves SS. PMID: 24835503; PMCID: PMC4231011.
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    111. Clinical implications and pathogenesis of esophageal remodeling in eosinophilic esophagitis. Gastroenterol Clin North Am. 2014 Jun; 43(2):297-316. Hirano I, Aceves SS. PMID: 24813517; PMCID: PMC4127387.
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    112. Remodeling and fibrosis in chronic eosinophil inflammation. Dig Dis. 2014; 32(1-2):15-21. Aceves SS. PMID: 24603375; PMCID: PMC4037288.
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    113. Unmet therapeutic needs in eosinophilic esophagitis. Dig Dis. 2014; 32(1-2):143-8. Aceves SS. PMID: 24603399; PMCID: PMC4037231.
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    114. Targeting AMCase reduces esophageal eosinophilic inflammation and remodeling in a mouse model of egg induced eosinophilic esophagitis. Int Immunopharmacol. 2014 Jan; 18(1):35-42. Cho JY, Rosenthal P, Miller M, Pham A, Aceves S, Sakuda S, Broide DH. PMID: 24239745; PMCID: PMC3908829.
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    115. Food allergy testing in eosinophilic esophagitis: what the gastroenterologist needs to know. Clin Gastroenterol Hepatol. 2014 Aug; 12(8):1216-23. Aceves SS. PMID: 24035776; PMCID: PMC4048803.
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    116. The management of eosinophilic esophagitis. J Allergy Clin Immunol Pract. 2013 Jul-Aug; 1(4):332-40; quiz 341-2. Greenhawt M, Aceves SS, Spergel JM, Rothenberg ME. PMID: 24565538.
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    117. Anti-IL-5 therapy reduces mast cell and IL-9 cell numbers in pediatric patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2013 Jun; 131(6):1576-82. Otani IM, Anilkumar AA, Newbury RO, Bhagat M, Beppu LY, Dohil R, Broide DH, Aceves SS. PMID: 23623266; PMCID: PMC3699422.
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    118. Working with the US Food and Drug Administration: progress and timelines in understanding and treating patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2012 Sep; 130(3):617-9. Rothenberg ME, Aceves S, Bonis PA, Collins MH, Gonsalves N, Gupta SK, Hirano I, Liacouras CA, Putnam PE, Spergel JM, Straumann A, Wershil BK, Furuta GT. PMID: 22935588; PMCID: PMC3828675.
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    119. Mutations of complement factor I and potential mechanisms of neuroinflammation in acute hemorrhagic leukoencephalitis. J Clin Immunol. 2013 Jan; 33(1):162-71. Broderick L, Gandhi C, Mueller JL, Putnam CD, Shayan K, Giclas PC, Peterson KS, Aceves SS, Sheets RM, Peterson BM, Newbury RO, Hoffman HM, Bastian JF. PMID: 22926405; PMCID: PMC3540165.
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    120. Eosinophilic gastrointestinal diseases--clinically diverse and histopathologically confounding. Semin Immunopathol. 2012 Sep; 34(5):715-31. Aceves S, Hirano I, Furuta GT, Collins MH. PMID: 22842863.
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    121. Pediatric and adult eosinophilic esophagitis: similarities and differences. Allergy. 2012 Apr; 67(4):477-90. Straumann A, Aceves SS, Blanchard C, Collins MH, Furuta GT, Hirano I, Schoepfer AM, Simon D, Simon HU. PMID: 22313241.
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    122. Transient PPI responsive esophageal eosinophilia may be a clinical sub-phenotype of pediatric eosinophilic esophagitis. Dig Dis Sci. 2012 May; 57(5):1413-9. Dohil R, Newbury RO, Aceves S. PMID: 22134787.
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    123. Tissue remodeling in patients with eosinophilic esophagitis: what lies beneath the surface? J Allergy Clin Immunol. 2011 Nov; 128(5):1047-9. Aceves SS. PMID: 22036097.
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    124. Siglec-F inhibition reduces esophageal eosinophilia and angiogenesis in a mouse model of eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2011 Oct; 53(4):409-16. Rubinstein E, Cho JY, Rosenthal P, Chao J, Miller M, Pham A, Aceves SS, Varki A, Broide DH. PMID: 21970996; PMCID: PMC3980963.
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    125. An antibody against IL-5 reduces numbers of esophageal intraepithelial eosinophils in children with eosinophilic esophagitis. Gastroenterology. 2011 Nov; 141(5):1593-604. Assa'ad AH, Gupta SK, Collins MH, Thomson M, Heath AT, Smith DA, Perschy TL, Jurgensen CH, Ortega HG, Aceves SS. PMID: 21835135.
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    126. Oral viscous budesonide therapy in children with epidermolysis bullosa and proximal esophageal strictures. J Pediatr Gastroenterol Nutr. 2011 Jun; 52(6):776-7. Dohil R, Aceves SS, Dohil MA. PMID: 21593650.
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    127. Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol. 2011 Jul; 128(1):3-20.e6; quiz 21-2. Liacouras CA, Furuta GT, Hirano I, Atkins D, Attwood SE, Bonis PA, Burks AW, Chehade M, Collins MH, Dellon ES, Dohil R, Falk GW, Gonsalves N, Gupta SK, Katzka DA, Lucendo AJ, Markowitz JE, Noel RJ, Odze RD, Putnam PE, Richter JE, Romero Y, Ruchelli E, Sampson HA, Schoepfer A, Shaheen NJ, Sicherer SH, Spechler S, Spergel JM, Straumann A, Wershil BK, Rothenberg ME, Aceves SS. PMID: 21477849.
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    128. Gastrointestinal manifestations of food allergies. Pediatr Clin North Am. 2011 Apr; 58(2):389-405, x. Wolfe JL, Aceves SS. PMID: 21453809.
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    129. Mast cells infiltrate the esophageal smooth muscle in patients with eosinophilic esophagitis, express TGF-β1, and increase esophageal smooth muscle contraction. J Allergy Clin Immunol. 2010 Dec; 126(6):1198-204.e4. Aceves SS, Chen D, Newbury RO, Dohil R, Bastian JF, Broide DH. PMID: 21047675.
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    130. Food allergy and eosinophilic esophagitis. Curr Opin Allergy Clin Immunol. 2010 Jun; 10(3):231-7. Chehade M, Aceves SS. PMID: 20410819.
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    131. Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial. Gastroenterology. 2010 Aug; 139(2):418-29. Dohil R, Newbury R, Fox L, Bastian J, Aceves S. PMID: 20457157.
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    132. Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51. J Allergy Clin Immunol. 2010 Apr; 125(4):879-888.e8. Caldwell JM, Blanchard C, Collins MH, Putnam PE, Kaul A, Aceves SS, Bouska CA, Rothenberg ME. PMID: 20371398; PMCID: PMC2865682.
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    133. Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nat Genet. 2010 Apr; 42(4):289-91. Rothenberg ME, Spergel JM, Sherrill JD, Annaiah K, Martin LJ, Cianferoni A, Gober L, Kim C, Glessner J, Frackelton E, Thomas K, Blanchard C, Liacouras C, Verma R, Aceves S, Collins MH, Brown-Whitehorn T, Putnam PE, Franciosi JP, Chiavacci RM, Grant SF, Abonia JP, Sleiman PM, Hakonarson H. PMID: 20208534; PMCID: PMC3740732.
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    134. A symptom scoring tool for identifying pediatric patients with eosinophilic esophagitis and correlating symptoms with inflammation. Ann Allergy Asthma Immunol. 2009 Nov; 103(5):401-6. Aceves SS, Newbury RO, Dohil MA, Bastian JF, Dohil R. PMID: 19927538.
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    135. Resolution of remodeling in eosinophilic esophagitis correlates with epithelial response to topical corticosteroids. Allergy. 2010 Jan; 65(1):109-16. Aceves SS, Newbury RO, Chen D, Mueller J, Dohil R, Hoffman H, Bastian JF, Broide DH. PMID: 19796194; PMCID: PMC2807896.
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    136. Relationships between eosinophilic inflammation, tissue remodeling, and fibrosis in eosinophilic esophagitis. Immunol Allergy Clin North Am. 2009 Feb; 29(1):197-211, xiii-xiv. Aceves SS, Ackerman SJ. PMID: 19141355; PMCID: PMC2665721.
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    137. Airway fibrosis and angiogenesis due to eosinophil trafficking in chronic asthma. Curr Mol Med. 2008 Aug; 8(5):350-8. Aceves SS, Broide DH. PMID: 18691061.
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    138. Integrated approach to treatment of children and adults with eosinophilic esophagitis. Gastrointest Endosc Clin N Am. 2008 Jan; 18(1):195-217; xi. Aceves SS, Furuta GT, Spechler SJ. PMID: 18061112.
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    139. Oral viscous budesonide: a potential new therapy for eosinophilic esophagitis in children. Am J Gastroenterol. 2007 Oct; 102(10):2271-9; quiz 2280. Aceves SS, Bastian JF, Newbury RO, Dohil R. PMID: 17581266.
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    140. Distinguishing eosinophilic esophagitis in pediatric patients: clinical, endoscopic, and histologic features of an emerging disorder. J Clin Gastroenterol. 2007 Mar; 41(3):252-6. Aceves SS, Newbury RO, Dohil R, Schwimmer J, Bastian JF. PMID: 17426462.
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    141. Esophageal remodeling in pediatric eosinophilic esophagitis. J Allergy Clin Immunol. 2007 Jan; 119(1):206-12. Aceves SS, Newbury RO, Dohil R, Bastian JF, Broide DH. PMID: 17208603.
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    142. Eosinophilic disorders in children. Curr Allergy Asthma Rep. 2006 Nov; 6(6):475-82. Wagelie-Steffen A, Aceves SS. PMID: 17026874.
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    143. A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis. Gastroenterology. 2006 Nov; 131(5):1381-91. Konikoff MR, Noel RJ, Blanchard C, Kirby C, Jameson SC, Buckmeier BK, Akers R, Cohen MB, Collins MH, Assa'ad AH, Aceves SS, Putnam PE, Rothenberg ME. PMID: 17101314.
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    144. Topical viscous budesonide suspension for treatment of eosinophilic esophagitis. J Allergy Clin Immunol. 2005 Sep; 116(3):705-6. Aceves SS, Dohil R, Newbury RO, Bastian JF. PMID: 16159647.
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    146. [CLINICAL INTEGRATION IN CARDIOLOGY]. Arch Inst Cardiol Mex. 1964 Jan-Feb; 34:4-10. ACEVES S. PMID: 14133253.
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    147. [RECENT ACQUISITIONS IN INTERNAL MEDICINE IN RELATION TO: CARDIOLOGY, DERMATOLOGY, GASTROENTEROLOGY, IMMUNOLOGY, NEPHROLOGY AND PNEUMOLOGY. II. CARDIOLOGY]. Gac Med Mex. 1963 Nov; 93:969-79. ACEVES S. PMID: 14107814.
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