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Michael Croft

TitleAdjunct Professor
InstitutionUniversity of California San Diego
DepartmentMedicine
Address9500 Gilman Drive #0656
La Jolla CA 92093
Phone858-752-6500
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    Collapse Research 
    Collapse Research Activities and Funding
    TWEAK and Skin Inflammation
    NIH/NIAMS R01AR072640Jul 18, 2018 - Apr 30, 2023
    Role: Principal Investigator
    LIGHT/TNFSF14 in allergic esophagitis remodeling
    NIH/NIDDK R01DK114457Apr 1, 2018 - Feb 28, 2022
    Role: Principal Investigator
    Training in Immunological Mechanisms
    NIH/NIAID T32AI125179Aug 1, 2016 - Jul 31, 2020
    Role: Principal Investigator
    Novel PTPRD interaction Controlling T cell Responsiveness
    NIH/NIAID R21AI123134Jan 15, 2016 - Dec 31, 2017
    Role: Principal Investigator
    Structural Characterization of 4-1BB-Galectin-9 Complexes
    NIH/NIAID R03AI110929Jul 1, 2014 - Jun 30, 2016
    Role: Principal Investigator
    Control of Airway Tolerance
    NIH/NIAID R01AI103021May 15, 2013 - Apr 30, 2018
    Role: Principal Investigator
    TNF Family Members and Control of Fibrotic Disease
    NIH/NIAID R21AI100905Jul 2, 2012 - Jun 30, 2014
    Role: Principal Investigator
    FACSAria II Cell Sorter
    NIH/NCRR S10RR027366Mar 7, 2011 - Mar 6, 2012
    Role: Principal Investigator
    Induction and maintenance of regulatory T cells
    NIH P01AI089624Jul 16, 2010 - Jun 30, 2015
    Role: Co-Investigator
    Tolerogenic Interactions of 4-1BB
    NIH/NIAID R21AI085291Feb 10, 2010 - Jan 31, 2011
    Role: Principal Investigator
    Airway inflammation and airway remodeling
    NIH/NIAID U19AI070535Jul 1, 2006 - Aug 31, 2021
    Role: Co-Investigator
    TNFR Members in T Cell Immunity to Vaccinia
    NIH/NIAID R01AI067341Jun 15, 2006 - May 31, 2011
    Role: Principal Investigator
    TNFR Members in T Cell Immunity to Vaccinia
    NIH/NIAID R56AI067341Dec 1, 2005 - Aug 31, 2013
    Role: Principal Investigator
    INITIATION AND PROPAGATION OF ASTHMATIC INFLAMMATION
    NIH/NIAID P01AI050498Sep 10, 2001 - Jun 30, 2007
    Role: Co-Investigator
    Regulation of T Cell Tolerance by OX40
    NIH/NCI R01CA091837Jul 1, 2001 - May 31, 2013
    Role: Principal Investigator
    The molecular basis of OX40 on CD4 T cells
    NIH/NIAID R01AI049453Apr 1, 2001 - Nov 30, 2012
    Role: Principal Investigator
    COSTIMULATORY INTERACTIONS DURING THE AGING PROCESS
    NIH/NIAID R03AI043298Aug 1, 1998 - Jul 31, 2001
    Role: Principal Investigator
    MODULATION OF OX-40 AND 4-1BB FUNCTION IN AGING
    NIH/NIA R03AG015638Jul 1, 1998 - Jun 30, 1999
    Role: Principal Investigator
    The Role of 4-1BB in T Cell and APC Interactions
    NIH/NIAID R01AI042944Apr 1, 1998 - Apr 30, 2011
    Role: Principal Investigator
    SIGNALING IN ALLERGIC INFLAMMATION
    NIH U19AI042244Sep 30, 1997 - Oct 15, 2001
    Role: Co-Investigator
    REGULATION OF PRIMARY T HELPER RESPONSES
    NIH/NIAID R29AI036259Aug 15, 1994 - Jul 31, 1999
    Role: Principal Investigator
    MULTIPURPOSE ARTHRITIS &MUSCULOSKELETAL DISEASE CENTER
    NIH/NIAMS P60AR040770Aug 1, 1991 - Feb 28, 2002
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bitra A, Doukov T, Croft M, Zajonc DM. Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier. J Biol Chem. 2018 Jun 29; 293(26):9958-9969. PMID: 29720398.
      View in: PubMed
    2. Publicover J, Gaggar A, Jespersen JM, Halac U, Johnson AJ, Goodsell A, Avanesyan L, Nishimura SL, Holdorf M, Mansfield KG, Judge JB, Koshti A, Croft M, Wakil AE, Rosenthal P, Pai E, Cooper S, Baron JL. An OX40/OX40L interaction directs successful immunity to hepatitis B virus. Sci Transl Med. 2018 Mar 21; 10(433). PMID: 29563320.
      View in: PubMed
    3. da Silva Antunes R, Mehta AK, Madge L, Tocker J, Croft M. TNFSF14 (LIGHT) Exhibits Inflammatory Activities in Lung Fibroblasts Complementary to IL-13 and TGF-ß. Front Immunol. 2018; 9:576. PMID: 29616048.
      View in: PubMed
    4. Desai P, Tahiliani V, Hutchinson TE, Dastmalchi F, Stanfield J, Abboud G, Thomas PG, Ware CF, Song J, Croft M, Salek-Ardakani S. The TNF Superfamily Molecule LIGHT Promotes the Generation of Circulating and Lung-Resident Memory CD8 T Cells following an Acute Respiratory Virus Infection. J Immunol. 2018 Apr 15; 200(8):2894-2904. PMID: 29514949.
      View in: PubMed
    5. Herro R, Shui JW, Zahner S, Sidler D, Kawakami Y, Kawakami T, Tamada K, Kronenberg M, Croft M. LIGHT-HVEM signaling in keratinocytes controls development of dermatitis. J Exp Med. 2018 Feb 05; 215(2):415-422. PMID: 29339444.
      View in: PubMed
    6. Claus M, Herro R, Wolf D, Buscher K, Rudloff S, Huynh-Do U, Burkly L, Croft M, Sidler D. The TWEAK/Fn14 pathway is required for calcineurin inhibitor toxicity of the kidneys. Am J Transplant. 2017 Dec 21. PMID: 29266762.
      View in: PubMed
    7. Bitra A, Doukov T, Wang J, Picarda G, Benedict CA, Croft M, Zajonc DM. Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling. J Biol Chem. 2018 Jan 26; 293(4):1317-1329. PMID: 29242193.
      View in: PubMed
    8. Madireddi S, Eun SY, Mehta AK, Birta A, Zajonc DM, Niki T, Hirashima M, Podack ER, Schreiber TH, Croft M. Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9. J Immunol. 2017 10 15; 199(8):2721-2728. PMID: 28877989.
      View in: PubMed
    9. Desai P, Abboud G, Stanfield J, Thomas PG, Song J, Ware CF, Croft M, Salek-Ardakani S. HVEM Imprints Memory Potential on Effector CD8 T Cells Required for Protective Mucosal Immunity. J Immunol. 2017 10 15; 199(8):2968-2975. PMID: 28864473.
      View in: PubMed
    10. Song DJ, Miller M, Beppu A, Rosenthal P, Das S, Karta M, Vuong C, Mehta AK, Croft M, Broide DH. Rhinovirus Infection of ORMDL3 Transgenic Mice Is Associated with Reduced Rhinovirus Viral Load and Airway Inflammation. J Immunol. 2017 10 01; 199(7):2215-2224. PMID: 28827284.
      View in: PubMed
    11. Lund SJ, Portillo A, Cavagnero K, Baum RE, Naji LH, Badrani JH, Mehta A, Croft M, Broide DH, Doherty TA. Leukotriene C4 Potentiates IL-33-Induced Group 2 Innate Lymphoid Cell Activation and Lung Inflammation. J Immunol. 2017 08 01; 199(3):1096-1104. PMID: 28667163.
      View in: PubMed
    12. Sidler D, Wu P, Herro R, Claus M, Wolf D, Kawakami Y, Kawakami T, Burkly L, Croft M. TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis. Nat Commun. 2017 May 22; 8:15395. PMID: 28530223.
      View in: PubMed
    13. Croft M, Siegel RM. Beyond TNF: TNF superfamily cytokines as targets for the treatment of rheumatic diseases. Nat Rev Rheumatol. 2017 Apr; 13(4):217-233. PMID: 28275260.
      View in: PubMed
    14. Croft M, Dubey C. Accessory Molecule and Costimulation Requirements for CD4 T Cell Response. Crit Rev Immunol. 2017; 37(2-6):261-290. PMID: 29773023.
      View in: PubMed
    15. Tahiliani V, Hutchinson TE, Abboud G, Croft M, Salek-Ardakani S. OX40 Cooperates with ICOS To Amplify Follicular Th Cell Development and Germinal Center Reactions during Infection. J Immunol. 2017 01 01; 198(1):218-228. PMID: 27895177.
      View in: PubMed
    16. Mehta AK, Gracias DT, Croft M. TNF activity and T cells. Cytokine. 2018 01; 101:14-18. PMID: 27531077.
      View in: PubMed
    17. Ley K, Pramod AB, Croft M, Ravichandran KS, Ting JP. How Mouse Macrophages Sense What Is Going On. Front Immunol. 2016; 7:204. PMID: 27313577; PMCID: PMC4890338.
    18. Miller M, Esnault S, Kurten RC, Kelly EA, Beppu A, Das S, Rosenthal P, Ramsdell J, Croft M, Zuraw B, Jarjour N, Hamid Q, Broide DH. Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma. J Allergy Clin Immunol. 2016 Aug; 138(2):596-599.e4. PMID: 27001159; PMCID: PMC4975994 [Available on 08/01/17].
    19. Lee-Chang C, Bodogai M, Moritoh K, Chen X, Wersto R, Sen R, Young HA, Croft M, Ferrucci L, Biragyn A. Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers. J Immunol. 2016 Apr 15; 196(8):3385-97. PMID: 26983789.
      View in: PubMed
    20. Herro R, Croft M. The control of tissue fibrosis by the inflammatory molecule LIGHT (TNF Superfamily member 14). Pharmacol Res. 2016 Feb; 104:151-5. PMID: 26748035; PMCID: PMC4712451 [Available on 02/01/17].
    21. Miller M, Beppu A, Rosenthal P, Pham A, Das S, Karta M, Song DJ, Vuong C, Doherty T, Croft M, Zuraw B, Zhang X, Gao X, Aceves S, Chouiali F, Hamid Q, Broide DH. Fstl1 Promotes Asthmatic Airway Remodeling by Inducing Oncostatin M. J Immunol. 2015 Oct 15; 195(8):3546-56. PMID: 26355153; PMCID: PMC4811198 [Available on 10/15/16].
    22. da Silva Antunes R, Madge L, Soroosh P, Tocker J, Croft M. The TNF Family Molecules LIGHT and Lymphotoxin aß Induce a Distinct Steroid-Resistant Inflammatory Phenotype in Human Lung Epithelial Cells. J Immunol. 2015 Sep 01; 195(5):2429-41. PMID: 26209626; PMCID: PMC4546856.
    23. Mehta AK, Duan W, Doerner AM, Traves SL, Broide DH, Proud D, Zuraw BL, Croft M. Rhinovirus infection interferes with induction of tolerance to aeroantigens through OX40 ligand, thymic stromal lymphopoietin, and IL-33. J Allergy Clin Immunol. 2016 Jan; 137(1):278-288.e6. PMID: 26100084; PMCID: PMC4684822 [Available on 01/01/17].
    24. Herro R, Antunes RDS, Aguilera AR, Tamada K, Croft M. The Tumor Necrosis Factor Superfamily Molecule LIGHT Promotes Keratinocyte Activity and Skin Fibrosis. J Invest Dermatol. 2015 Aug; 135(8):2109-2118. PMID: 25789702; PMCID: PMC4504809.
    25. Herro R, Da Silva Antunes R, Aguilera AR, Tamada K, Croft M. Tumor necrosis factor superfamily 14 (LIGHT) controls thymic stromal lymphopoietin to drive pulmonary fibrosis. J Allergy Clin Immunol. 2015 Sep; 136(3):757-68. PMID: 25680454; PMCID: PMC4532661.
    26. Bang BR, Kim SJ, Yagita H, Croft M, Kang YJ. Inhibition of 4-1BBL-regulated TLR response in macrophages ameliorates endotoxin-induced sepsis in mice. Eur J Immunol. 2015 Mar; 45(3):886-92. PMID: 25501291; PMCID: PMC4418486.
    27. Duan W, Croft M. Control of regulatory T cells and airway tolerance by lung macrophages and dendritic cells. Ann Am Thorac Soc. 2014 Dec; 11 Suppl 5:S306-13. PMID: 25525738; PMCID: PMC4298969.
    28. Eun SY, Lee SW, Xu Y, Croft M. 4-1BB ligand signaling to T cells limits T cell activation. J Immunol. 2015 Jan 01; 194(1):134-41. PMID: 25404362; PMCID: PMC4272921.
    29. Buchan S, Manzo T, Flutter B, Rogel A, Edwards N, Zhang L, Sivakumaran S, Ghorashian S, Carpenter B, Bennett C, Freeman GJ, Sykes M, Croft M, Al-Shamkhani A, Chakraverty R. OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence. J Immunol. 2015 Jan 01; 194(1):125-133. PMID: 25404365; PMCID: PMC4272895.
    30. Lee-Chang C, Bodogai M, Moritoh K, Olkhanud PB, Chan AC, Croft M, Mattison JA, Holst PJ, Gress RE, Ferrucci L, Hakim F, Biragyn A. Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity. Blood. 2014 Aug 28; 124(9):1450-9. PMID: 25037628; PMCID: PMC4148767.
    31. Madireddi S, Eun SY, Lee SW, Nemcovicová I, Mehta AK, Zajonc DM, Nishi N, Niki T, Hirashima M, Croft M. Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies. J Exp Med. 2014 Jun 30; 211(7):1433-48. PMID: 24958847; PMCID: PMC4076583.
    32. Croft M. The TNF family in T cell differentiation and function--unanswered questions and future directions. Semin Immunol. 2014 Jun; 26(3):183-90. PMID: 24613728; PMCID: PMC4099277.
    33. Flynn R, Hutchinson T, Murphy KM, Ware CF, Croft M, Salek-Ardakani S. CD8 T cell memory to a viral pathogen requires trans cosignaling between HVEM and BTLA. PLoS One. 2013; 8(10):e77991. PMID: 24205056; PMCID: PMC3812147.
    34. Boettler T, Choi YS, Salek-Ardakani S, Cheng Y, Moeckel F, Croft M, Crotty S, von Herrath M. Exogenous OX40 stimulation during lymphocytic choriomeningitis virus infection impairs follicular Th cell differentiation and diverts CD4 T cells into the effector lineage by upregulating Blimp-1. J Immunol. 2013 Nov 15; 191(10):5026-35. PMID: 24101548; PMCID: PMC3915873.
    35. Ma J, Bang BR, Lu J, Eun SY, Otsuka M, Croft M, Tobias P, Han J, Takeuchi O, Akira S, Karin M, Yagita H, Kang YJ. The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation. Sci Signal. 2013 Oct 01; 6(295):ra87. PMID: 24084649; PMCID: PMC4004444.
    36. So T, Croft M. Regulation of PI-3-Kinase and Akt Signaling in T Lymphocytes and Other Cells by TNFR Family Molecules. Front Immunol. 2013; 4:139. PMID: 23760533; PMCID: PMC3675380.
    37. Lei F, Song J, Haque R, Xiong X, Fang D, Wu Y, Lens SM, Croft M, Song J. Transgenic expression of survivin compensates for OX40-deficiency in driving Th2 development and allergic inflammation. Eur J Immunol. 2013 Jul; 43(7):1914-24. PMID: 23616302; PMCID: PMC3876962.
    38. Doherty TA, Khorram N, Lund S, Mehta AK, Croft M, Broide DH. Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production. J Allergy Clin Immunol. 2013 Jul; 132(1):205-13. PMID: 23688412.
      View in: PubMed
    39. Guimond DM, Cam NR, Hirve N, Duan W, Lambris JD, Croft M, Tsoukas CD. Regulation of immune responsiveness in vivo by disrupting an early T-cell signaling event using a cell-permeable peptide. PLoS One. 2013; 8(5):e63645. PMID: 23667652; PMCID: PMC3646824.
    40. Gerlic M, Faustin B, Postigo A, Yu EC, Proell M, Gombosuren N, Krajewska M, Flynn R, Croft M, Way M, Satterthwait A, Liddington RC, Salek-Ardakani S, Matsuzawa S, Reed JC. Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation. Proc Natl Acad Sci U S A. 2013 May 07; 110(19):7808-13. PMID: 23603272; PMCID: PMC3651467.
    41. Huang LR, Wohlleber D, Reisinger F, Jenne CN, Cheng RL, Abdullah Z, Schildberg FA, Odenthal M, Dienes HP, van Rooijen N, Schmitt E, Garbi N, Croft M, Kurts C, Kubes P, Protzer U, Heikenwalder M, Knolle PA. Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection. Nat Immunol. 2013 Jun; 14(6):574-83. PMID: 23584070.
      View in: PubMed
    42. Soroosh P, Doherty TA, Duan W, Mehta AK, Choi H, Adams YF, Mikulski Z, Khorram N, Rosenthal P, Broide DH, Croft M. Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance. J Exp Med. 2013 Apr 08; 210(4):775-88. PMID: 23547101; PMCID: PMC3620360.
    43. Croft M, Benedict CA, Ware CF. Clinical targeting of the TNF and TNFR superfamilies. Nat Rev Drug Discov. 2013 Feb; 12(2):147-68. PMID: 23334208.
      View in: PubMed
    44. Zhao Y, Tahiliani V, Salek-Ardakani S, Croft M. Targeting 4-1BB (CD137) to enhance CD8 T cell responses with poxviruses and viral antigens. Front Immunol. 2012; 3:332. PMID: 23162550; PMCID: PMC3492829.
    45. Boettler T, Moeckel F, Cheng Y, Heeg M, Salek-Ardakani S, Crotty S, Croft M, von Herrath MG. OX40 facilitates control of a persistent virus infection. PLoS Pathog. 2012 Sep; 8(9):e1002913. PMID: 22969431; PMCID: PMC3435255.
    46. Lee SW, Park Y, Eun SY, Madireddi S, Cheroutre H, Croft M. Cutting edge: 4-1BB controls regulatory activity in dendritic cells through promoting optimal expression of retinal dehydrogenase. J Immunol. 2012 Sep 15; 189(6):2697-701. PMID: 22896640; PMCID: PMC3436963.
    47. Doherty TA, Khorram N, Chang JE, Kim HK, Rosenthal P, Croft M, Broide DH. STAT6 regulates natural helper cell proliferation during lung inflammation initiated by Alternaria. Am J Physiol Lung Cell Mol Physiol. 2012 Oct 01; 303(7):L577-88. PMID: 22865552; PMCID: PMC3469584.
    48. Bae JS, Choi JK, Moon JH, Kim EC, Croft M, Lee HW. Novel transmembrane protein 126A (TMEM126A) couples with CD137L reverse signals in myeloid cells. Cell Signal. 2012 Dec; 24(12):2227-36. PMID: 22885069; PMCID: PMC3466360.
    49. Goulding J, Bogue R, Tahiliani V, Croft M, Salek-Ardakani S. CD8 T cells are essential for recovery from a respiratory vaccinia virus infection. J Immunol. 2012 Sep 01; 189(5):2432-40. PMID: 22826318; PMCID: PMC3496758.
    50. So T, Croft M. Regulation of the PKC?-NF-?B Axis in T Lymphocytes by the Tumor Necrosis Factor Receptor Family Member OX40. Front Immunol. 2012; 3:133. PMID: 22654884; PMCID: PMC3361009.
    51. Fousteri G, Jasinski J, Dave A, Nakayama M, Pagni P, Lambolez F, Juntti T, Sarikonda G, Cheng Y, Croft M, Cheroutre H, Eisenbarth G, von Herrath M. Following the fate of one insulin-reactive CD4 T cell: conversion into Teffs and Tregs in the periphery controls diabetes in NOD mice. Diabetes. 2012 May; 61(5):1169-79. PMID: 22403296; PMCID: PMC3331775.
    52. Doherty TA, Khorram N, Sugimoto K, Sheppard D, Rosenthal P, Cho JY, Pham A, Miller M, Croft M, Broide DH. Alternaria induces STAT6-dependent acute airway eosinophilia and epithelial FIZZ1 expression that promotes airway fibrosis and epithelial thickness. J Immunol. 2012 Mar 15; 188(6):2622-9. PMID: 22327070; PMCID: PMC3294141.
    53. Croft M, Duan W, Choi H, Eun SY, Madireddi S, Mehta A. TNF superfamily in inflammatory disease: translating basic insights. Trends Immunol. 2012 Mar; 33(3):144-52. PMID: 22169337; PMCID: PMC3299395.
    54. Duan W, So T, Mehta AK, Choi H, Croft M. Inducible CD4+LAP+Foxp3- regulatory T cells suppress allergic inflammation. J Immunol. 2011 Dec 15; 187(12):6499-507. PMID: 22079987; PMCID: PMC3237738.
    55. Bresson D, Fousteri G, Manenkova Y, Croft M, von Herrath M. Antigen-specific prevention of type 1 diabetes in NOD mice is ameliorated by OX40 agonist treatment. J Autoimmun. 2011 Dec; 37(4):342-51. PMID: 22063316; PMCID: PMC3811160.
    56. Zhao Y, Croft M. Dispensable role for 4-1BB and 4-1BBL in development of vaccinia virus-specific CD8 T cells. Immunol Lett. 2012 Jan 30; 141(2):220-6. PMID: 22037570; PMCID: PMC3243825.
    57. Zhao Y, Adams YF, Croft M. Preferential replication of vaccinia virus in the ovaries is independent of immune regulation through IL-10 and TGF-ß. Viral Immunol. 2011 Oct; 24(5):387-96. PMID: 21958373; PMCID: PMC3189386.
    58. Magalhaes JG, Rubino SJ, Travassos LH, Le Bourhis L, Duan W, Sellge G, Geddes K, Geddes K, Reardon C, Lechmann M, Carneiro LA, Selvanantham T, Fritz JH, Taylor BC, Artis D, Mak TW, Comeau MR, Croft M, Girardin SE, Philpott DJ. Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation. Proc Natl Acad Sci U S A. 2011 Sep 06; 108(36):14896-901. PMID: 21856952; PMCID: PMC3169112.
    59. Doherty TA, Croft M. Therapeutic potential of targeting TNF/TNFR family members in asthma. Immunotherapy. 2011 Aug; 3(8):919-21. PMID: 21843077.
      View in: PubMed
    60. Salek-Ardakani S, Moutaftsi M, Sette A, Croft M. Targeting OX40 promotes lung-resident memory CD8 T cell populations that protect against respiratory poxvirus infection. J Virol. 2011 Sep; 85(17):9051-9. PMID: 21715499; PMCID: PMC3165842.
    61. Lee SW, Choi H, Eun SY, Fukuyama S, Croft M. Nitric oxide modulates TGF-beta-directive signals to suppress Foxp3+ regulatory T cell differentiation and potentiate Th1 development. J Immunol. 2011 Jun 15; 186(12):6972-80. PMID: 21555530; PMCID: PMC3113707.
    62. Doherty TA, Soroosh P, Khorram N, Fukuyama S, Rosenthal P, Cho JY, Norris PS, Choi H, Scheu S, Pfeffer K, Zuraw BL, Ware CF, Broide DH, Croft M. The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling. Nat Med. 2011 May; 17(5):596-603. PMID: 21499267; PMCID: PMC3097134.
    63. Salek-Ardakani S, Choi YS, Rafii-El-Idrissi Benhnia M, Flynn R, Arens R, Shoenberger S, Crotty S, Croft M, Salek-Ardakani S. B cell-specific expression of B7-2 is required for follicular Th cell function in response to vaccinia virus. J Immunol. 2011 May 01; 186(9):5294-303. PMID: 21441451; PMCID: PMC3089765.
    64. Soroosh P, Doherty TA, So T, Mehta AK, Khorram N, Norris PS, Scheu S, Pfeffer K, Ware C, Croft M. Herpesvirus entry mediator (TNFRSF14) regulates the persistence of T helper memory cell populations. J Exp Med. 2011 Apr 11; 208(4):797-809. PMID: 21402741; PMCID: PMC3135347.
    65. Fousteri G, Dave A, Morin B, Omid S, Croft M, von Herrath MG. Nasal cardiac myosin peptide treatment and OX40 blockade protect mice from acute and chronic virally-induced myocarditis. J Autoimmun. 2011 May; 36(3-4):210-20. PMID: 21333491; PMCID: PMC3079777.
    66. So T, Choi H, Croft M. OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling. J Immunol. 2011 Mar 15; 186(6):3547-55. PMID: 21289304; PMCID: PMC3079230.
    67. So T, Soroosh P, Eun SY, Altman A, Croft M. Antigen-independent signalosome of CARMA1, PKC?, and TNF receptor-associated factor 2 (TRAF2) determines NF-?B signaling in T cells. Proc Natl Acad Sci U S A. 2011 Feb 15; 108(7):2903-8. PMID: 21282629; PMCID: PMC3041086.
    68. Salek-Ardakani S, Flynn R, Arens R, Yagita H, Smith GL, Borst J, Schoenberger SP, Croft M. The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice. J Clin Invest. 2011 Jan; 121(1):296-307. PMID: 21183789.
      View in: PubMed
    69. Duan W, Mehta AK, Magalhaes JG, Ziegler SF, Dong C, Philpott DJ, Croft M. Innate signals from Nod2 block respiratory tolerance and program T(H)2-driven allergic inflammation. J Allergy Clin Immunol. 2010 Dec; 126(6):1284-93.e10. PMID: 21051079; PMCID: PMC3058679.
    70. Humphreys IR, Lee SW, Jones M, Loewendorf A, Gostick E, Price DA, Benedict CA, Ware CF, Croft M. Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells. Eur J Immunol. 2010 Oct; 40(10):2762-8. PMID: 20722077; PMCID: PMC2967573.
    71. Fousteri G, Chan JR, Zheng Y, Whiting C, Dave A, Bresson D, Croft M, von Herrath M. Virtual optimization of nasal insulin therapy predicts immunization frequency to be crucial for diabetes protection. Diabetes. 2010 Dec; 59(12):3148-58. PMID: 20864513; PMCID: PMC2992777.
    72. Hsieh EH, Fernandez X, Wang J, Hamer M, Calvillo S, Croft M, Kwon BS, Lo DD. CD137 is required for M cell functional maturation but not lineage commitment. Am J Pathol. 2010 Aug; 177(2):666-76. PMID: 20616340; PMCID: PMC2913358.
    73. Gong J, Yang NS, Croft M, Weng IC, Sun L, Liu FT, Chen SS. The antigen presentation function of bone marrow-derived mast cells is spatiotemporally restricted to a subset expressing high levels of cell surface FcepsilonRI and MHC II. BMC Immunol. 2010 Jun 30; 11:34. PMID: 20591187; PMCID: PMC2904267.
    74. Salek-Ardakani S, Croft M. Tumor necrosis factor receptor/tumor necrosis factor family members in antiviral CD8 T-cell immunity. J Interferon Cytokine Res. 2010 Apr; 30(4):205-18. PMID: 20377415; PMCID: PMC3001890.
    75. Croft M. Control of immunity by the TNFR-related molecule OX40 (CD134). Annu Rev Immunol. 2010; 28:57-78. PMID: 20307208; PMCID: PMC2882161.
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