Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Jesus Rivera-Nieves

    TitleProfessor of Medicine
    SchoolUniversity of California, San Diego
    Address9500 Gilman Drive #0063
    CA La Jolla 92093
    vCardDownload vCard

      Collapse Biography 
      Collapse Education and Training
      Fellowship Training2001University of Virginia, Charlottesville, VA
      Research Fellowship1998Pulmonary Medicine Branch, National Hearth, Lung and Blood Institute, National Institutes of Health
      Residency1993University of Maryland, Baltimore, MD
      MD1990University of Puerto Rico, San Juan, PR
      BS1985University of Puerto Rico, San Juan, PR

      Collapse Research 
      Collapse Research Activities and Funding
      Novel Traffic-targeted Therapies for IBD
      NIH/NIDDK R01DK108670Jan 1, 2016 - Dec 31, 2020
      Role: Principal Investigator
      Dendritic Cell Manipulation: A Novel Therapeutic for Inflammatory Bowel Disease
      VA I01BX001051Apr 1, 2011 - Dec 31, 2015
      Role: Principal Investigator
      Targeting L-Selectin in Chronic Murine Ileitis
      NIH/NIDDK R01DK080212Jul 20, 2009 - Jun 30, 2014
      Role: Principal Investigator
      Role of L-selectin and its Ligands in Chronic Murine Ileitis
      NIH/NIDDK R03DK073280Sep 1, 2006 - Aug 31, 2009
      Role: Principal Investigator
      Lymphocyte Trafficking by Chemokines/Adhesion Molecules in Crohn's Disease
      NIH/NIDDK K08DK067254Jul 1, 2004 - Jun 30, 2010
      Role: Principal Investigator

      Collapse ORNG Applications 
      Collapse Websites

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. McNamee EN, Rivera-Nieves J. Defective Lymphatics in Crohn's Disease: Tertiary Lymphoid Follicles Plug the Gap. Gastroenterology. 2017 Mar; 152(4):908-910. PMID: 28153586.
        View in: PubMed
      2. Bamias G, Rivera-Nieves J. Targeting S1P Receptors, A New Mechanism of Action for Inflammatory Bowel Disease Therapy. Gastroenterology. 2016 Nov; 151(5):1025-1027. PMID: 27693331.
        View in: PubMed
      3. Karuppuchamy T, Behrens EH, González-Cabrera P, Sarkisyan G, Gima L, Boyer JD, Bamias G, Jedlicka P, Veny M, Clark D, Peach R, Scott F, Rosen H, Rivera-Nieves J. Sphingosine-1-phosphate receptor-1 (S1P1) is expressed by lymphocytes, dendritic cells, and endothelium and modulated during inflammatory bowel disease. Mucosal Immunol. 2017 Jan; 10(1):162-171. PMID: 27049060.
        View in: PubMed
      4. Rivera-Nieves J, Bamias G. Anti-Interleukin-12/23 Blockade Offers Novel Therapeutic Opportunities for the "Difficult" Patient with Crohn's Disease. Gastroenterology. 2016 05; 150(5):1237-1239. PMID: 27018181.
        View in: PubMed
      5. Lee NS, Pola S, Groessl EJ, Rivera-Nieves J, Ho SB. Opportunities for Improvement in the Care of Patients Hospitalized for Inflammatory Bowel Disease-Related Colitis. Dig Dis Sci. 2016 Apr; 61(4):1003-12. PMID: 26860508.
        View in: PubMed
      6. Ley K, Rivera-Nieves J, Sandborn WJ, Shattil S. Integrin-based therapeutics: biological basis, clinical use and new drugs. Nat Rev Drug Discov. 2016 Mar; 15(3):173-83. PMID: 26822833; PMCID: PMC4890615.
      7. Boland BS, Boyle DL, Sandborn WJ, Firestein GS, Levesque BG, Hillman J, Zhang B, Proudfoot J, Eckmann L, Ernst PB, Rivera-Nieves J, Pola S, Copur-Dahi N, Zou G, Chang JT. Validation of gene expression biomarker analysis for biopsy-based clinical trials in Crohn's disease. Inflamm Bowel Dis. 2015 Feb; 21(2):323-30. PMID: 25545378; PMCID: PMC4404151.
      8. Boland BS, Boyle DL, Sandborn WJ, Firestein GS, Levesque BG, Hillman J, Zhang B, Proudfoot J, Eckmann L, Ernst PB, Rivera-Nieves J, Pola S, Copur-Dahi N, Chang JT. Validated gene expression biomarker analysis for biopsy-based clinical trials in ulcerative colitis. Aliment Pharmacol Ther. 2014 Sep; 40(5):477-85. PMID: 25041724; PMCID: PMC4143528.
      9. Mosli MH, Rivera-Nieves J, Feagan BG. T-cell trafficking and anti-adhesion strategies in inflammatory bowel disease: current and future prospects. Drugs. 2014 Mar; 74(3):297-311. PMID: 24452878.
        View in: PubMed
      10. Bamias G, Clark DJ, Rivera-Nieves J. Leukocyte traffic blockade as a therapeutic strategy in inflammatory bowel disease. Curr Drug Targets. 2013 Nov; 14(12):1490-500. PMID: 23621509; PMCID: PMC3779486.
      11. Rivera-Nieves J, Abreu MT. A call for investment in education of US minorities in the 21(st) century. Gastroenterology. 2013 May; 144(5):863-7. PMID: 23523955; PMCID: PMC3684384.
      12. Pola S, Patel D, Ramamoorthy S, McLemore E, Fahmy M, Rivera-Nieves J, Chang JT, Evans E, Docherty M, Talamini M, Sandborn WJ. Strategies for the care of adults hospitalized for active ulcerative colitis. Clin Gastroenterol Hepatol. 2012 Dec; 10(12):1315-1325.e4. PMID: 22835577; PMCID: PMC4226798.
      13. Gorfu G, Rivera-Nieves J, Hoang S, Abbott DW, Arbenz-Smith K, Azar DW, Pizarro TT, Cominelli F, McDuffie M, Ley K. Beta7 integrin deficiency suppresses B cell homing and attenuates chronic ileitis in SAMP1/YitFc mice. J Immunol. 2010 Nov 01; 185(9):5561-8. PMID: 20926792; PMCID: PMC3228636.
      14. Eltzschig HK, Rivera-Nieves J, Colgan SP. Targeting the A2B adenosine receptor during gastrointestinal ischemia and inflammation. Expert Opin Ther Targets. 2009 Nov; 13(11):1267-77. PMID: 19769545; PMCID: PMC4077533.
      15. Smith E, von Vietinghoff S, Stark MA, Zarbock A, Sanders JM, Duley A, Rivera-Nieves J, Bender TP, Ley K. T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo. J Immunol. 2009 Nov 01; 183(9):5685-93. PMID: 19843951; PMCID: PMC2893017.
      16. Gorfu G, Rivera-Nieves J, Ley K. Role of beta7 integrins in intestinal lymphocyte homing and retention. Curr Mol Med. 2009 Sep; 9(7):836-50. PMID: 19860663; PMCID: PMC2770881.
      17. Barnes SL, Vidrich A, Wang ML, Wu GD, Cominelli F, Rivera-Nieves J, Bamias G, Cohn SM. Resistin-like molecule beta (RELMbeta/FIZZ2) is highly expressed in the ileum of SAMP1/YitFc mice and is associated with initiation of ileitis. J Immunol. 2007 Nov 15; 179(10):7012-20. PMID: 17982092.
        View in: PubMed
      18. Bamias G, Okazawa A, Rivera-Nieves J, Arseneau KO, De La Rue SA, Pizarro TT, Cominelli F. Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis. J Immunol. 2007 Feb 01; 178(3):1809-18. PMID: 17237431.
        View in: PubMed
      19. Bamias G, Mishina M, Nyce M, Ross WG, Kollias G, Rivera-Nieves J, Pizarro TT, Cominelli F. Role of TL1A and its receptor DR3 in two models of chronic murine ileitis. Proc Natl Acad Sci U S A. 2006 May 30; 103(22):8441-6. PMID: 16698931; PMCID: PMC1482511.
      20. Bachmann C, Klibanov AL, Olson TS, Sonnenschein JR, Rivera-Nieves J, Cominelli F, Ley KF, Lindner JR, Pizarro TT. Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease. Gastroenterology. 2006 Jan; 130(1):8-16. PMID: 16401463.
        View in: PubMed
      21. Odashima M, Bamias G, Rivera-Nieves J, Linden J, Nast CC, Moskaluk CA, Marini M, Sugawara K, Kozaiwa K, Otaka M, Watanabe S, Cominelli F. Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease. Gastroenterology. 2005 Jul; 129(1):26-33. PMID: 16012931.
        View in: PubMed
      22. Bamias G, Martin C, Mishina M, Ross WG, Rivera-Nieves J, Marini M, Cominelli F. Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation. Gastroenterology. 2005 Mar; 128(3):654-66. PMID: 15765401.
        View in: PubMed
      23. Spencer LT, Paone G, Krein PM, Rouhani FN, Rivera-Nieves J, Brantly ML. Role of human neutrophil peptides in lung inflammation associated with alpha1-antitrypsin deficiency. Am J Physiol Lung Cell Mol Physiol. 2004 Mar; 286(3):L514-20. PMID: 14594730.
        View in: PubMed
      24. Burns RC, Rivera-Nieves J, Moskaluk CA, Matsumoto S, Cominelli F, Ley K. Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice. Gastroenterology. 2001 Dec; 121(6):1428-36. PMID: 11729122.
        View in: PubMed
      25. Kosiewicz MM, Nast CC, Krishnan A, Rivera-Nieves J, Moskaluk CA, Matsumoto S, Kozaiwa K, Cominelli F. Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease. J Clin Invest. 2001 Mar; 107(6):695-702. PMID: 11254669; PMCID: PMC208944.
      26. Rivera-Nieves J, Kozaiwa K, Parrish CR, Iezzoni J, Berg CL. Marked transaminase elevation in anorexia nervosa. Dig Dis Sci. 2000 Oct; 45(10):1959-63. PMID: 11117567.
        View in: PubMed
      27. Rivera-Nieves J, Battle E, Alfert J. Image of the month. Esophageal foreign body. Gastroenterology. 2000 Jan; 118(1):6, 243. PMID: 17165207.
        View in: PubMed
      Jesus's Networks
      Derived automatically from this person's publications.
      People in Profiles who have published with this person.
      Similar People
      People who share similar concepts with this person.
      Same Department
      Physical Neighbors
      People whose addresses are nearby this person.