Gabriel Silva

Title(s)Professor, Bioengineering
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research Activities and Funding
    Experimental Testing and Validation of a Quantum Dot FRET Calcium Sensor
    NIH R21EB017898Sep 30, 2013 - Aug 31, 2015
    Role: Principal Investigator
    High Throughput Mapping of Neuronal and Glial Networks
    NIH R01NS054736Apr 1, 2006 - Mar 31, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Identifying steady state in the network dynamics of spiking neural networks. Heliyon. 2023 Mar; 9(3):e13913. George VK, Gupta A, Silva GA. PMID: 36967881; PMCID: PMC10036509.
      View in: PubMed   Mentions:
    2. Super-Selective Reconstruction of Causal and Direct Connectivity With Application to in vitro iPSC Neuronal Networks. Front Neurosci. 2021; 15:647877. Puppo F, Pré D, Bang AG, Silva GA. PMID: 34335152; PMCID: PMC8323822.
      View in: PubMed   Mentions: 1  
    3. All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors. Front Cell Neurosci. 2021; 15:671549. Puppo F, Sadegh S, Trujillo CA, Thunemann M, Campbell EP, Vandenberghe M, Shan X, Akkouh IA, Miller EW, Bloodgood BL, Silva GA, Dale AM, Einevoll GT, Djurovic S, Andreassen OA, Muotri AR, Devor A. PMID: 34122014; PMCID: PMC8193062.
      View in: PubMed   Mentions: 3  
    4. Computing Temporal Sequences Associated With Dynamic Patterns on the C. elegans Connectome. Front Syst Neurosci. 2021; 15:564124. George VK, Puppo F, Silva GA. PMID: 33767613; PMCID: PMC7985353.
      View in: PubMed   Mentions: 1  
    5. Generalizable Machine Learning in Neuroscience Using Graph Neural Networks. Front Artif Intell. 2021; 4:618372. Wang PY, Sapra S, George VK, Silva GA. PMID: 33748747; PMCID: PMC7971515.
      View in: PubMed   Mentions: 5  
    6. The Effect of Signaling Latencies and Node Refractory States on the Dynamics of Networks. Neural Comput. 2019 12; 31(12):2492-2522. Silva GA. PMID: 31614102.
      View in: PubMed   Mentions: 5     Fields:    
    7. A New Frontier: The Convergence of Nanotechnology, Brain Machine Interfaces, and Artificial Intelligence. Front Neurosci. 2018; 12:843. Silva GA. PMID: 30505265; PMCID: PMC6250836.
      View in: PubMed   Mentions: 9  
    8. An Optimized Structure-Function Design Principle Underlies Efficient Signaling Dynamics in Neurons. Sci Rep. 2018 Jul 11; 8(1):10460. Puppo F, George V, Silva GA. PMID: 29992977; PMCID: PMC6041316.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    9. The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements. Philos Trans R Soc Lond B Biol Sci. 2016 10 05; 371(1705). Uhlirova H, Kiliç K, Tian P, Sakadžic S, Gagnon L, Thunemann M, Desjardins M, Saisan PA, Nizar K, Yaseen MA, Hagler DJ, Vandenberghe M, Djurovic S, Andreassen OA, Silva GA, Masliah E, Kleinfeld D, Vinogradov S, Buxton RB, Einevoll GT, Boas DA, Dale AM, Devor A. PMID: 27574309; PMCID: PMC5003857.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    10. Towards high-resolution retinal prostheses with direct optical addressing and inductive telemetry. J Neural Eng. 2016 10; 13(5):056008. Ha S, Khraiche ML, Akinin A, Jing Y, Damle S, Kuang Y, Bauchner S, Lo YH, Freeman WR, Silva GA, Cauwenberghs G. PMID: 27529371.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    11. Cell type specificity of neurovascular coupling in cerebral cortex. Elife. 2016 05 31; 5. Uhlirova H, Kiliç K, Tian P, Thunemann M, Desjardins M, Saisan PA, Sakadžic S, Ness TV, Mateo C, Cheng Q, Weldy KL, Razoux F, Vandenberghe M, Cremonesi JA, Ferri CG, Nizar K, Sridhar VB, Steed TC, Abashin M, Fainman Y, Masliah E, Djurovic S, Andreassen OA, Silva GA, Boas DA, Kleinfeld D, Buxton RB, Einevoll GT, Dale AM, Devor A. PMID: 27244241; PMCID: PMC4933561.
      View in: PubMed   Mentions: 110     Fields:    Translation:AnimalsCells
    12. exomeSuite: Whole exome sequence variant filtering tool for rapid identification of putative disease causing SNVs/indels. Genomics. 2014 Feb-Mar; 103(2-3):169-76. Maranhao B, Biswas P, Duncan JL, Branham KE, Silva GA, Naeem MA, Khan SN, Riazuddin S, Hejtmancik JF, Heckenlively JR, Riazuddin SA, Lee PL, Ayyagari R. PMID: 24603341; PMCID: PMC4146529.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    13. The challenge of connecting the dots in the B.R.A.I.N. Neuron. 2013 Oct 16; 80(2):270-4. Devor A, Bandettini PA, Boas DA, Bower JM, Buxton RB, Cohen LB, Dale AM, Einevoll GT, Fox PT, Franceschini MA, Friston KJ, Fujimoto JG, Geyer MA, Greenberg JH, Halgren E, Hämäläinen MS, Helmchen F, Hyman BT, Jasanoff A, Jernigan TL, Judd LL, Kim SG, Kleinfeld D, Kopell NJ, Kutas M, Kwong KK, Larkum ME, Lo EH, Magistretti PJ, Mandeville JB, Masliah E, Mitra PP, Mobley WC, Moskowitz MA, Nimmerjahn A, Reynolds JH, Rosen BR, Salzberg BM, Schaffer CB, Silva GA, So PT, Spitzer NC, Tootell RB, Van Essen DC, Vanduffel W, Vinogradov SA, Wald LL, Wang LV, Weber B, Yodh AG. PMID: 24139032; PMCID: PMC3864648.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    14. A positive feedback cell signaling nucleation model of astrocyte dynamics. Front Neuroeng. 2013; 6:4. Macdonald CL, Silva GA. PMID: 23847529; PMCID: PMC3706728.
      View in: PubMed   Mentions: 1  
    15. Nanotechnologies for stimulating and recording excitable events in neurons and cardiomyocytes. Discov Med. 2013 Jun; 15(85):357-65. Silva GA, Khraiche ML. PMID: 23819950.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    16. In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase. J Neurosci. 2013 May 08; 33(19):8411-22. Nizar K, Uhlirova H, Tian P, Saisan PA, Cheng Q, Reznichenko L, Weldy KL, Steed TC, Sridhar VB, MacDonald CL, Cui J, Gratiy SL, Sakadzic S, Boas DA, Beka TI, Einevoll GT, Chen J, Masliah E, Dale AM, Silva GA, Devor A. PMID: 23658179; PMCID: PMC3712855.
      View in: PubMed   Mentions: 114     Fields:    Translation:AnimalsCells
    17. Targeting the brain: advances in drug delivery. Curr Pharm Biotechnol. 2012 Sep; 13(12):2417-26. Blumling Iii JP, Silva GA. PMID: 23016646.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    18. Direct inductive stimulation for energy-efficient wireless neural interfaces. Annu Int Conf IEEE Eng Med Biol Soc. 2012; 2012:883-6. Ha S, Khraiche ML, Silva GA, Cauwenberghs G. PMID: 23366034.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    19. The need for the emergence of mathematical neuroscience: beyond computation and simulation. Front Comput Neurosci. 2011; 5:51. Silva GA. PMID: 22131972; PMCID: PMC3223358.
      View in: PubMed   Mentions: 4  
    20. Ultra-high photosensitivity silicon nanophotonics for retinal prosthesis: electrical characteristics. Annu Int Conf IEEE Eng Med Biol Soc. 2011; 2011:2933-6. Khraiche ML, Lo Y, Wang D, Cauwenberghs G, Freeman W, Silva GA. PMID: 22254955.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Nanotechnology applications and approaches for neuroregeneration and drug delivery to the central nervous system. Ann N Y Acad Sci. 2010 Jun; 1199:221-30. Silva GA. PMID: 20633128.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    22. Mapping the spatiotemporal dynamics of calcium signaling in cellular neural networks using optical flow. Ann Biomed Eng. 2010 Aug; 38(8):2520-31. Buibas M, Yu D, Nizar K, Silva GA. PMID: 20300851; PMCID: PMC2900593.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    23. Amyloid β-peptide directly induces spontaneous calcium transients, delayed intercellular calcium waves and gliosis in rat cortical astrocytes. ASN Neuro. 2010 Jan 25; 2(1):e00026. Chow SK, Yu D, Macdonald CL, Buibas M, Silva GA. PMID: 20001968; PMCID: PMC2810812.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    24. Chapter 2 - Quantum dot nanotechnologies for neuroimaging. Prog Brain Res. 2009; 180:19-34. Silva GA. PMID: 20302827.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    25. Quantum dot labeling and imaging of glial fibrillary acidic protein intermediate filaments and gliosis in the rat neural retina and dissociated astrocytes. J Nanosci Nanotechnol. 2009 Aug; 9(8):5047-54. Pathak S, Tolentino R, Nguyen K, D'Amico L, Barron E, Cheng L, Freeman WR, Silva GA. PMID: 19928184.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    26. Characterization of Calcium-Mediated Intracellular and Intercellular Signaling in the rMC-1 Glial Cell Line. Cell Mol Bioeng. 2009 Mar 01; 2(1):144-155. Yu D, Buibas M, Chow SK, Lee IY, Singer Z, Silva GA. PMID: 19890481; PMCID: PMC2771886.
      View in: PubMed   Mentions: 10  
    27. Nanotechnology approaches to crossing the blood-brain barrier and drug delivery to the CNS. BMC Neurosci. 2008 Dec 10; 9 Suppl 3:S4. Silva GA. PMID: 19091001; PMCID: PMC2604882.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimals
    28. Diffusion modeling of ATP signaling suggests a partially regenerative mechanism underlies astrocyte intercellular calcium waves. Front Neuroeng. 2008; 1:1. Macdonald CL, Yu D, Buibas M, Silva GA. PMID: 18958241; PMCID: PMC2526017.
      View in: PubMed   Mentions: 15  
    29. Toxicity and intraocular properties of a novel long-acting anti-proliferative and anti-angiogenic compound IMS2186. Curr Eye Res. 2008 Jul; 33(7):599-609. Falkenstein IA, Cheng L, Wong-Staal F, Tammewar AM, Barron EC, Silva GA, Li QX, Yu D, Hysell M, Liu G, Ke N, Macdonald JE, Freeman WR. PMID: 18600493; PMCID: PMC2664073.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    30. The role of abnormal vitreomacular adhesion in age-related macular degeneration: spectral optical coherence tomography and surgical results. Am J Ophthalmol. 2008 Aug; 146(2):218-227. Mojana F, Cheng L, Bartsch DU, Silva GA, Kozak I, Nigam N, Freeman WR. PMID: 18538742; PMCID: PMC2735863.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    31. Automated detection of intercellular signaling in astrocyte networks using the converging squares algorithm. J Neurosci Methods. 2008 May 30; 170(2):294-9. Hashemi M, Buibas M, Silva GA. PMID: 18328570; PMCID: PMC2637820.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    32. Stem cell sources and therapeutic approaches for central nervous system and neural retinal disorders. Neurosurg Focus. 2008; 24(3-4):E11. Yu D, Silva GA. PMID: 18341387; PMCID: PMC2647750.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    33. Testing of intraocular drugs for clinical use. Invest Ophthalmol Vis Sci. 2007 Nov; 48(11):4861-3. Kozak I, Cheng L, Silva GA, Freeman WR. PMID: 17962431.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    34. Characterization of the functional binding properties of antibody conjugated quantum dots. Nano Lett. 2007 Jul; 7(7):1839-45. Pathak S, Davidson MC, Silva GA. PMID: 17536868.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    35. What impact will nanotechnology have on neurology? Nat Clin Pract Neurol. 2007 Apr; 3(4):180-1. Silva GA. PMID: 17410106.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Nanotechnology approaches for drug and small molecule delivery across the blood brain barrier. Surg Neurol. 2007 Feb; 67(2):113-6. Silva GA. PMID: 17254859.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    37. The effect of recombinant human hyaluronidase on dexamethasone penetration into the posterior segment of the eye after sub-Tenon's injection. J Ocul Pharmacol Ther. 2006 Oct; 22(5):362-9. Kozak I, Kayikcioglu OR, Cheng L, Falkenstein I, Silva GA, Yu DX, Freeman WR. PMID: 17076631.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    38. Comparison of standard surface chemistries for culturing mesenchymal stem cells prior to neural differentiation. Biomaterials. 2006 Aug; 27(24):4333-9. Ho M, Yu D, Davidsion MC, Silva GA. PMID: 16647114.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    39. Quantum dot applications to neuroscience: new tools for probing neurons and glia. J Neurosci. 2006 Feb 15; 26(7):1893-5. Pathak S, Cao E, Davidson MC, Jin S, Silva GA. PMID: 16481420; PMCID: PMC6674918.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    40. Neuroscience nanotechnology: progress, opportunities and challenges. Nat Rev Neurosci. 2006 Jan; 7(1):65-74. Silva GA. PMID: 16371951.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    41. Nanotechnology approaches for the regeneration and neuroprotection of the central nervous system. Surg Neurol. 2005 Apr; 63(4):301-6. Silva GA. PMID: 15808703.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    42. Introduction to nanotechnology and its applications to medicine. Surg Neurol. 2004 Mar; 61(3):216-20. Silva GA. PMID: 14984987.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    43. Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science. 2004 Feb 27; 303(5662):1352-5. Silva GA, Czeisler C, Niece KL, Beniash E, Harrington DA, Kessler JA, Stupp SI. PMID: 14739465.
      View in: PubMed   Mentions: 447     Fields:    Translation:AnimalsCells
    44. Step response of mouse rod photoreceptors modeled in terms of elemental photic signals. IEEE Trans Biomed Eng. 2004 Jan; 51(1):3-12. Silva GA, Pepperberg DR. PMID: 14723488.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
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