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Flossie Wong-Staal

Title(s)Emeritus Professor, Medicine
SchoolHealth Sciences
Address9500 Gilman Drive #9111E
La Jolla CA 92093
Phone858-552-8585
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    LENTIVIRAL VECTORS FOR HIV GENE THERAPY
    NIH/NIAID P01AI045992Aug 15, 1999 - Jul 31, 2004
    Role: Co-Principal Investigator
    CONFERENCE ON AIDS PATHOGENESIS
    NIH/NIAID R13AI043951Jan 1, 1999 - Dec 31, 1999
    Role: Principal Investigator
    RIBOZYME GENE THERAPY FOR CD4 AND CD34 CELLS
    NIH/NIDDK R01DK054675Sep 30, 1998 - Jul 31, 2003
    Role: Principal Investigator
    CELLULAR FACTORS INVOLVED IN NUCLEAR EXPORT OF VIRAL RNA
    NIH/NIGMS R01GM056089Jan 1, 1998 - Dec 31, 2001
    Role: Principal Investigator
    Center for AIDS Research
    NIH/NIAID P30AI036214Apr 1, 1997 - May 31, 2012
    Role: Co-Principal Investigator
    FACS VANTAGE CELL SORTER
    NIH/NCRR S10RR011852Feb 1, 1997 - Jun 30, 1998
    Role: Principal Investigator
    TRANSGENIC MICE MODEL FOR RIBOZYME EXPRESSION AND ACT
    NIH/FIC R03TW000678Apr 1, 1996 - Nov 30, 1999
    Role: Principal Investigator
    DEVELOPMENT OF GENE DELIVERY VECTOR
    NIH/NIAID U19AI036612Sep 1, 1994 - Feb 28, 2001
    Role: Principal Investigator
    RIBOZYME GENE THERAPY FOR CD4 AND CD34 CELLS
    NIH/NIDDK R01DK049618Aug 1, 1994 - Sep 30, 1998
    Role: Principal Investigator
    REV/REX TRANSACTIVATION PATHWAY OF HIV/HTLV
    NIH/NIAID R01AI031378Jul 1, 1991 - May 31, 1996
    Role: Principal Investigator
    HIV TAT PROTEIN AND KAPOSI'S SARCOMA PATHOGENESIS
    NIH/NCI R01CA052412Feb 1, 1991 - Jan 31, 1994
    Role: Principal Investigator
    IN VIVO AND IN VITRO PARAMETERS OF HIV-2 PATHOGENICITY
    NIH/NIAID R01AI029889Jul 1, 1990 - Jun 30, 1995
    Role: Principal Investigator
    STRATEGIES FOR HIV VACCINE DEVELOPMENT
    NIH/NIAID U01AI030238Jun 15, 1990 - Nov 30, 1996
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Effect of Anti-CD4 Antibody UB-421 on HIV-1 Rebound after Treatment Interruption. N Engl J Med. 2019 04 18; 380(16):1535-1545. Wang CY, Wong WW, Tsai HC, Chen YH, Kuo BS, Lynn S, Blazkova J, Clarridge KE, Su HW, Lin CY, Tseng FC, Lai A, Yang FH, Lin CH, Tseng W, Lin HY, Finstad CL, Wong-Staal F, Hanson CV, Chun TW, Liao MJ. PMID: 30995373.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    2. Safety and antiviral activity of the HCV entry inhibitor ITX5061 in treatment-naive HCV-infected adults: a randomized, double-blind, phase 1b study. J Infect Dis. 2014 Mar 01; 209(5):658-67. Sulkowski MS, Kang M, Matining R, Wyles D, Johnson VA, Morse GD, Amorosa V, Bhattacharya D, Coughlin K, Wong-Staal F, Glesby MJ. PMID: 24041792.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCellsCTClinical Trials
    3. Discovery of ITX 4520: a highly potent orally bioavailable hepatitis C virus entry inhibitor. Bioorg Med Chem Lett. 2012 Aug 01; 22(15):4955-61. Mittapalli GK, Zhao F, Jackson A, Gao H, Lee H, Chow S, Kaur MP, Nguyen N, Zamboni R, McKelvy J, Wong-Staal F, Macdonald JE. PMID: 22784640.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    4. Discovery of highly potent small molecule Hepatitis C Virus entry inhibitors. Bioorg Med Chem Lett. 2011 Nov 15; 21(22):6852-5. Mittapalli GK, Jackson A, Zhao F, Lee H, Chow S, McKelvy J, Wong-Staal F, Macdonald JE. PMID: 21978675.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    5. Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission. J Virol. 2011 Jan; 85(1):596-605. Brimacombe CL, Grove J, Meredith LW, Hu K, Syder AJ, Flores MV, Timpe JM, Krieger SE, Baumert TF, Tellinghuisen TL, Wong-Staal F, Balfe P, McKeating JA. PMID: 20962076.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansCells
    6. Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors. J Hepatol. 2011 Jan; 54(1):48-55. Syder AJ, Lee H, Zeisel MB, Grove J, Soulier E, Macdonald J, Chow S, Chang J, Baumert TF, McKeating JA, McKelvy J, Wong-Staal F. PMID: 20932595.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    7. Hepatitis C virus infection of neuroepithelioma cell lines. Gastroenterology. 2010 Oct; 139(4):1365-74. Fletcher NF, Yang JP, Farquhar MJ, Hu K, Davis C, He Q, Dowd K, Ray SC, Krieger SE, Neyts J, Baumert TF, Balfe P, McKeating JA, Wong-Staal F. PMID: 20538002.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    8. A method for detecting and preventing negative RNA interference in preparation of lentiviral vectors for siRNA delivery. RNA. 2009 Apr; 15(4):732-40. Zhou D, Zhang J, Wang C, Bliesath JR, He Q, Yu D, Li-He Z, Wong-Staal F. PMID: 19244361.
      View in: PubMed   Mentions: 3     Fields:    
    9. Screening of small-molecule compounds as inhibitors of HCV entry. Methods Mol Biol. 2009; 510:295-304. Yang JP, Zhou D, Wong-Staal F. PMID: 19009270.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    10. Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy. PLoS One. 2008; 3(12):e3951. Yu DH, Macdonald J, Liu G, Lee AS, Ly M, Davis T, Ke N, Zhou D, Wong-Staal F, Li QX. PMID: 19079611.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    11. Comparisons of RNAi approaches for validation of human RNA helicase A as an essential factor in hepatitis C virus replication. J Virol Methods. 2008 Dec; 154(1-2):216-9. He QS, Tang H, Zhang J, Truong K, Wong-Staal F, Zhou D. PMID: 18782589.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    12. Oncolytic virotherapy as a personalized cancer vaccine. Int J Cancer. 2008 Aug 01; 123(3):493-9. Li QX, Liu G, Wong-Staal F. PMID: 18500742.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    13. Toxicity and intraocular properties of a novel long-acting anti-proliferative and anti-angiogenic compound IMS2186. Curr Eye Res. 2008 Jul; 33(7):599-609. Falkenstein IA, Cheng L, Wong-Staal F, Tammewar AM, Barron EC, Silva GA, Li QX, Yu D, Hysell M, Liu G, Ke N, Macdonald JE, Freeman WR. PMID: 18600493.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    14. Generation of shRNA pool library: a revision of the biological technique from the viewpoint of chemistry. Chembiochem. 2008 Jun 16; 9(9):1365-7. Zhou D, Wang C, Zhang J, Bliesath J, He QS, Ke N, Yu D, Li Q, Zhang LH, Wong-Staal F. PMID: 18435449.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    15. Biochemical characterization of genetic mutations of GPR56 in patients with bilateral frontoparietal polymicrogyria (BFPP). Biochem Biophys Res Commun. 2008 Feb 08; 366(2):314-20. Ke N, Ma H, Diedrich G, Chionis J, Liu G, Yu DH, Wong-Staal F, Li QX. PMID: 18042463.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    16. Isoginkgetin enhances adiponectin secretion from differentiated adiposarcoma cells via a novel pathway involving AMP-activated protein kinase. J Endocrinol. 2007 Sep; 194(3):569-78. Liu G, Grifman M, Macdonald J, Moller P, Wong-Staal F, Li QX. PMID: 17761896.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    17. A more efficient RNAi inducible system for tight regulation of gene expression in mammalian cells and xenograft animals. RNA. 2007 Aug; 13(8):1375-83. Zhang J, Wang C, Ke N, Bliesath J, Chionis J, He QS, Li QX, Chatterton JE, Wong-Staal F, Zhou D. PMID: 17616554.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    18. Orphan G protein-coupled receptor GPR56 plays a role in cell transformation and tumorigenesis involving the cell adhesion pathway. Mol Cancer Ther. 2007 Jun; 6(6):1840-50. Ke N, Sundaram R, Liu G, Chionis J, Fan W, Rogers C, Awad T, Grifman M, Yu D, Wong-Staal F, Li QX. PMID: 17575113.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    19. Ribozyme technology for cancer gene target identification and validation. Adv Cancer Res. 2007; 96:103-43. Li QX, Tan P, Ke N, Wong-Staal F. PMID: 17161678.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    20. MDDD, a 4,9-diazapyrenium derivative, is selectively toxic to glioma cells by inducing growth arrest at G0/G1 independently of p53. Invest New Drugs. 2006 Nov; 24(6):489-98. Yu DH, Macdonald J, Josephs S, Liu Q, Nguy V, Tor Y, Wong-Staal F, Li QX. PMID: 16633716.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    21. A new inducible RNAi xenograft model for assessing the staged tumor response to mTOR silencing. Exp Cell Res. 2006 Sep 10; 312(15):2726-34. Ke N, Zhou D, Chatterton JE, Liu G, Chionis J, Zhang J, Tsugawa L, Lynn R, Yu D, Meyhack B, Wong-Staal F, Li QX. PMID: 16765945.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    22. A novel RNAi library based on partially randomized consensus sequences of nuclear receptors: identifying the receptors involved in amyloid beta degradation. Genomics. 2006 Sep; 88(3):282-92. Yang JP, Fan W, Rogers C, Chatterton JE, Bliesath J, Liu G, Ke N, Wang CY, Rhoades K, Wong-Staal F, Li QX. PMID: 16631344.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. Therapy with ribozyme to the proliferating cell nuclear antigen-ribozyme and 5-fluorouracil of experimental choroidal neovascularization in rats. J Ocul Pharmacol Ther. 2006 Feb; 22(1):1-9. Kayikcioglu OR, Falkenstein I, Cheng L, Kozak I, La Bree L, Azen SP, Wong-Staal F, Paoni NF, Freeman WR. PMID: 16503769.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    24. PHTS, a novel putative tumor suppressor, is involved in the transformation reversion of HeLaHF cells independently of the p53 pathway. Exp Cell Res. 2006 Apr 01; 312(6):865-76. Yu DH, Fan W, Liu G, Nguy V, Chatterton JE, Long S, Ke N, Meyhack B, Bruengger A, Brachat A, Wong-Staal F, Li QX. PMID: 16413018.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    25. RNA interference and potential applications. Curr Top Med Chem. 2006; 6(9):901-11. Zhou D, He QS, Wang C, Zhang J, Wong-Staal F. PMID: 16787283.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    26. Recent development of RNAi in drug target discovery and validation. Drug Discov Today Technol. 2006; 3(3):293-300. Liu G, Wong-Staal F, Li QX. PMID: 24980531.
      View in: PubMed   Mentions: 2     Fields:    
    27. A 96-well surrogate survival assay coupled with a special short interfering RNA vector for assessing cancer gene targets with enhanced signal/noise ratio and its utility in HTS for cancer therapeutic targets. Assay Drug Dev Technol. 2005 Aug; 3(4):401-11. Yu DH, Chatterton JE, Bliesath JR, Sundaram R, Ke N, Nguy V, Meyhack B, Wong-Staal F, Li QX. PMID: 16180995.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    28. Identification of cellular cofactors for human immunodeficiency virus replication via a ribozyme-based genomics approach. J Virol. 2004 Dec; 78(23):12829-37. Waninger S, Kuhen K, Hu X, Chatterton JE, Wong-Staal F, Tang H. PMID: 15542635.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    29. Nuclear hormone receptor NR4A2 is involved in cell transformation and apoptosis. Cancer Res. 2004 Nov 15; 64(22):8208-12. Ke N, Claassen G, Yu DH, Albers A, Fan W, Tan P, Grifman M, Hu X, Defife K, Nguy V, Meyhack B, Brachat A, Wong-Staal F, Li QX. PMID: 15548686.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    30. RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator. Eur J Biochem. 2004 Sep; 271(18):3741-51. Tetsuka T, Uranishi H, Sanda T, Asamitsu K, Yang JP, Wong-Staal F, Okamoto T. PMID: 15355351.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    31. Relative gene-silencing efficiencies of small interfering RNAs targeting sense and antisense transcripts from the same genetic locus. Nucleic Acids Res. 2004; 32(15):4609-17. Hu X, Hipolito S, Lynn R, Abraham V, Ramos S, Wong-Staal F. PMID: 15333693.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    32. Transduction of cell lines and primary cells by FIV-packaged HIV vectors. Mol Ther. 2004 Jul; 10(1):181-90. Morris KV, Gilbert J, Wong-Staal F, Gasmi M, Looney DJ. PMID: 15272479.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    33. The HIV-1 HLA-A2-SLYNTVATL is a help-independent CTL epitope. J Immunol. 2004 May 01; 172(9):5249-61. Kan-Mitchell J, Bisikirska B, Wong-Staal F, Schaubert KL, Bajcz M, Bereta M. PMID: 15100263.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    34. One-week 96-well soft agar growth assay for cancer target validation. Biotechniques. 2004 May; 36(5):826-8, 830, 832-3. Ke N, Albers A, Claassen G, Yu DH, Chatterton JE, Hu X, Meyhack B, Wong-Staal F, Li QX. PMID: 15152603.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    35. Arginine methylation of RNA helicase a determines its subcellular localization. J Biol Chem. 2004 May 28; 279(22):22795-8. Smith WA, Schurter BT, Wong-Staal F, David M. PMID: 15084609.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    36. Generation of dendritic cells from lentiviral vector-transduced CD34+ cells from HIV+ donors. J Med Virol. 2003 Jun; 70(2):183-6. Gruber A, Chen I, Kuhen KL, Wheat JC, Law P, Wong-Staal F. PMID: 12696103.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    37. Inverse Genomics as a powerful tool to identify novel targets for the treatment of neurodegenerative diseases. Mech Ageing Dev. 2003 Jan; 124(1):125-32. Rhoades K, Wong-Staal F. PMID: 12618015.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    38. Functional interaction of Sam68 and heterogeneous nuclear ribonucleoprotein K. Oncogene. 2002 Oct 17; 21(47):7187-94. Yang JP, Reddy TR, Truong KT, Suhasini M, Wong-Staal F. PMID: 12370808.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    39. Novel technologies for studying virus-host interaction and discovering new drug targets for HCV and HIV. Curr Opin Pharmacol. 2002 Oct; 2(5):541-7. Tang H, Peng T, Wong-Staal F. PMID: 12324256.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    40. Integrated approaches to therapeutic target gene discovery. Curr Opin Drug Discov Devel. 2002 Sep; 5(5):683-9. DeFife KM, Wong-Staal F. PMID: 12630288.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    41. Human immunodeficiency virus type 2 (HIV-2) vector-mediated in vivo gene transfer into adult rabbit retina. Curr Eye Res. 2002 Mar; 24(3):196-201. Cheng L, Chaidhawangul S, Wong-Staal F, Gilbert J, Poeschla E, Toyoguchi M, El-Bradey M, Bergeron-Lynn G, Soules KA, Freeman WR. PMID: 12221527.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    42. A role for KH domain proteins (Sam68-like mammalian proteins and quaking proteins) in the post-transcriptional regulation of HIV replication. J Biol Chem. 2002 Feb 22; 277(8):5778-84. Reddy TR, Suhasini M, Xu W, Yeh LY, Yang JP, Wu J, Artzt K, Wong-Staal F. PMID: 11741900.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    43. Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation. Mol Cell Biol. 2001 Dec; 21(24):8357-64. Krüger M, Beger C, Welch PJ, Barber JR, Manns MP, Wong-Staal F. PMID: 11713272.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    44. Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells. J Biol Chem. 2002 Jan 18; 277(3):1770-9. Cortés MJ, Wong-Staal F, Lama J. PMID: 11704677.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    45. HIV-2 and SIV vector systems. Somat Cell Mol Genet. 2001 Nov; 26(1-6):83-98. Gilbert JR, Wong-Staal F. PMID: 12465463.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    46. Differential effects of HIV-1 protease inhibitors on dendritic cell immunophenotype and function. J Biol Chem. 2001 Dec 21; 276(51):47840-3. Gruber A, Wheat JC, Kuhen KL, Looney DJ, Wong-Staal F. PMID: 11602580.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    47. C-SPACE (cleavage-specific amplification of cDNA ends): a novel method of ribozyme-mediated gene identification. Nucleic Acids Res. 2001 Oct 01; 29(19):E94. Krüger M, Beger C, Welch PJ, Barber JR, Wong-Staal F. PMID: 11574696.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    48. Altered immunophenotype of dendritic cells generated from HIV infected subjects. Immunol Lett. 2001 Oct 01; 78(3):209-11. Gruber A, Looney DJ, Ibanez M, Wong-Staal F. PMID: 11578697.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    49. Mapping the functional domains of HAP95, a protein that binds RNA helicase A and activates the constitutive transport element of type D retroviruses. J Biol Chem. 2001 Aug 17; 276(33):30694-700. Yang JP, Tang H, Reddy TR, Wong-Staal F. PMID: 11402034.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    50. Approaches to gene therapy for human immunodeficiency virus infection. Hum Gene Ther. 2001 Jun 10; 12(9):1013-9. Buchschacher GL, Wong-Staal F. PMID: 11399224.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    51. Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach. Proc Natl Acad Sci U S A. 2001 Jan 02; 98(1):130-5. Beger C, Pierce LN, Kruger M, Marcusson EG, Robbins JM, Welcsh P, Welch PJ, Welte K, King MC, Barber JR, Wong-Staal F. PMID: 11136250.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    52. Specific interaction between RNA helicase A and Tap, two cellular proteins that bind to the constitutive transport element of type D retrovirus. J Biol Chem. 2000 Oct 20; 275(42):32694-700. Tang H, Wong-Staal F. PMID: 10924507.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    53. General effect of Sam68 on Rev/Rex regulated expression of complex retroviruses. Oncogene. 2000 Aug 17; 19(35):4071-4. Reddy TR, Xu WD, Wong-Staal F. PMID: 10962565.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    54. Dendritic cells transduced by multiply deleted HIV-1 vectors exhibit normal phenotypes and functions and elicit an HIV-specific cytotoxic T-lymphocyte response in vitro. Blood. 2000 Aug 15; 96(4):1327-33. Gruber A, Kan-Mitchell J, Kuhen KL, Mukai T, Wong-Staal F. PMID: 10942374.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    55. Sam68, RNA helicase A and Tap cooperate in the post-transcriptional regulation of human immunodeficiency virus and type D retroviral mRNA. Oncogene. 2000 Jul 27; 19(32):3570-5. Reddy TR, Tang H, Xu W, Wong-Staal F. PMID: 10951562.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    56. Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach. Proc Natl Acad Sci U S A. 2000 Jul 18; 97(15):8566-71. Kruger M, Beger C, Li QX, Welch PJ, Tritz R, Leavitt M, Barber JR, Wong-Staal F. PMID: 10900014.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    57. A novel shuttle protein binds to RNA helicase A and activates the retroviral constitutive transport element. J Biol Chem. 2000 Jul 14; 275(28):21396-401. Westberg C, Yang JP, Tang H, Reddy TR, Wong-Staal F. PMID: 10748171.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    58. Development of lentiviral vectors for gene therapy for human diseases. Blood. 2000 Apr 15; 95(8):2499-504. Buchschacher GL, Wong-Staal F. PMID: 10753827.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    59. Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev. Nat Med. 1999 Jun; 5(6):635-42. Reddy TR, Xu W, Mau JK, Goodwin CD, Suhasini M, Tang H, Frimpong K, Rose DW, Wong-Staal F. PMID: 10371501.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    60. The carboxyl terminus of RNA helicase A contains a bidirectional nuclear transport domain. Mol Cell Biol. 1999 May; 19(5):3540-50. Tang H, McDonald D, Middlesworth T, Hope TJ, Wong-Staal F. PMID: 10207077.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    61. A role for RNA helicase A in post-transcriptional regulation of HIV type 1. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):709-14. Li J, Tang H, Mullen TM, Westberg C, Reddy TR, Rose DW, Wong-Staal F. PMID: 9892698.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    62. Mobilization of peripheral blood progenitor cells for human immunodeficiency virus-infected individuals. Exp Hematol. 1999 Jan; 27(1):147-54. Law P, Lane TA, Gervaix A, Looney D, Schwarz L, Young D, Ramos S, Wong-Staal F, Recktenwald D, Ho AD. PMID: 9923453.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    63. Lentivirus replication and regulation. Annu Rev Genet. 1999; 33:133-70. Tang H, Kuhen KL, Wong-Staal F. PMID: 10690406.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    64. Use of ribozymes to inhibit gene expression. Methods Enzymol. 1999; 306:207-25. Krüger M, Beger C, Wong-Staal F. PMID: 10432456.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    65. A controlled, Phase 1 clinical trial to evaluate the safety and effects in HIV-1 infected humans of autologous lymphocytes transduced with a ribozyme that cleaves HIV-1 RNA. Hum Gene Ther. 1998 Nov 01; 9(16):2407-25. Wong-Staal F, Poeschla EM, Looney DJ. PMID: 9829540.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCellsCTClinical Trials
    66. Genetic variation in a human immunodeficiency virus type 2 live-virus Macaca nemestrina vaccine model. J Virol. 1998 Oct; 72(10):7871-84. Radaelli A, Kraus G, Schmidt A, Badel P, McClure J, Hu SL, Morton W, De Giuli Morghen C, Wong-Staal F, Looney D. PMID: 9733824.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    67. Identification of a human immunodeficiency virus type 2 (HIV-2) encapsidation determinant and transduction of nondividing human cells by HIV-2-based lentivirus vectors. J Virol. 1998 Aug; 72(8):6527-36. Poeschla E, Gilbert J, Li X, Huang S, Ho A, Wong-Staal F. PMID: 9658096.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    68. Transduction of CD34+ cells by a vesicular stomach virus protein G (VSV-G) pseudotyped HIV-1 vector. Stable gene expression in progeny cells, including dendritic cells. J Hum Virol. 1998 Jul-Aug; 1(5):346-52. Li X, Mukai T, Young D, Frankel S, Law P, Wong-Staal F. PMID: 10195262.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
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