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    Alice Yu

    TitleEmeritus Professor
    SchoolUniversity of California, San Diego
    DepartmentPediatrics
    Address200 W. Arbor Drive #8447
    CA San Diego 92103
    Phone858-246-0027
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      Collapse Research 
      Collapse Research Activities and Funding
      Predicting toxicity and success of anti-GD2 immunotherapy of neuroblastoma
      NIH R01CA164132Apr 1, 2012 - Mar 31, 2015
      Role: Principal Investigator
      IMMUNE MONITOR FOR COG TRIAL OF ANTI-GD2 IN NEUROBLASTOMA
      NIH R01FD002319Sep 30, 2003 - May 31, 2010
      Role: Principal Investigator
      CLINICAL TRIAL OF ANTIID VACCINE FOR NEUROBLASTOMA
      NIH R21CA078806Jul 1, 1998 - Jun 30, 2000
      Role: Principal Investigator
      EXPLOITATION OF FREQUENT P16 DELETION IN T-ALL THERAPY
      NIH R21CA070397Apr 1, 1996 - Mar 31, 1998
      Role: Principal Investigator
      CLINICAL UTILITY OF A NEUROBLASTOMA MONOCLONAL ANTIBODY
      NIH R01CA040186Sep 1, 1985 - Nov 30, 1988
      Role: Principal Investigator
      General Clinical Research Center
      NIH M01RR000827Mar 1, 1974 - Nov 30, 2010
      Role: Co-Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Carvunis AR, Wang T, Skola D, Yu A, Chen J, Kreisberg JF, Ideker T. Evidence for a common evolutionary rate in metazoan transcriptional networks. Elife. 2015; 4. PMID: 26682651.
        View in: PubMed
      2. Williams RT, Yu A, Diccianni MB, Theodorakis EA, Batova A. Erratum: renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy. J Exp Clin Cancer Res. 2014; 33(1):95. PMID: 25480670.
        View in: PubMed
      3. Sonawane P, Cho HE, Tagde A, Verlekar D, Yu A, Reynolds CP, Kang MH. Metabolic characteristics of 13-cis-retinoic acid (isotretinoin) and anti-tumour activity of the 13-cis-retinoic acid metabolite 4-oxo-13-cis-retinoic acid in neuroblastoma. Br J Pharmacol. 2014 Dec; 171(23):5330-44. PMID: 25039756.
        View in: PubMed
      4. Cheng JY, Wang SH, Lin J, Tsai YC, Yu J, Wu JC, Hung JT, Lin JJ, Wu YY, Yeh KT, Yu A. Globo-h ceramide shed from cancer cells triggers translin-associated factor x-dependent angiogenesis. Cancer Res. 2014 Dec 1; 74(23):6856-66. PMID: 25281721.
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      5. Chang CH, Fan TC, Yu JC, Liao GS, Lin YC, Shih AC, Li WH, Yu A. The prognostic significance of RUNX2 and miR-10a/10b and their inter-relationship in breast cancer. J Transl Med. 2014; 12(1):257. PMID: 25266482.
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      6. Fu CH, Lin RJ, Yu J, Chang WW, Liao GS, Chang WY, Tseng LM, Tsai YF, Yu JC, Yu A. A novel oncogenic role of inositol phosphatase SHIP2 in ER-negative breast cancer stem cells: involvement of JNK/vimentin activation. Stem Cells. 2014 Aug; 32(8):2048-60. PMID: 24802135.
        View in: PubMed
      7. Barnhill LM, Williams RT, Cohen O, Kim Y, Batova A, Mielke JA, Messer K, Pu M, Bao L, Yu A, Diccianni MB. High Expression of CAI2, a 9p21-Embedded Long Noncoding RNA, Contributes to Advanced-Stage Neuroblastoma. Cancer Res. 2014 Jul 15; 74(14):3753-63. PMID: 25028366.
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      8. Hung JT, Tsai YC, Lin WD, Jan JT, Lin KH, Huang JR, Cheng JY, Chen MW, Wong CH, Yu A. Potent adjuvant effects of novel NKT stimulatory glycolipids on hemagglutinin based DNA vaccine for H5N1 influenza virus. Antiviral Res. 2014 Jul; 107:110-8. PMID: 24786174.
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      9. Lin JJ, Huang CS, Yu J, Liao GS, Lien HC, Hung JT, Lin RJ, Chou FP, Yeh KT, Yu A. Malignant phyllodes tumors display mesenchymal stem cell features and aldehyde dehydrogenase/disialoganglioside identify their tumor stem cells. Breast Cancer Res. 2014; 16(2):R29. PMID: 24670249.
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      10. Terme M, Dorvillius M, Cochonneau D, Chaumette T, Xiao W, Diccianni MB, Barbet J, Yu A, Paris F, Sorkin LS, Birklé S. Chimeric Antibody c.8B6 to O-Acetyl-GD2 Mediates the Same Efficient Anti-Neuroblastoma Effects as Therapeutic ch14.18 Antibody to GD2 without Antibody Induced Allodynia. PLoS One. 2014; 9(2):e87210. PMID: 24520328.
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      11. Williams RT, Barnhill LM, Kuo HH, Lin WD, Batova A, Yu A, Diccianni MB. Chimeras of p14ARF and p16: Functional Hybrids with the Ability to Arrest Growth. PLoS One. 2014; 9(2):e88219. PMID: 24505435.
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      12. Kelner MJ, Diccianni MB, Yu A, Rutherford MR, Estes LA, Morgenstern R. Absence of MGST1 mRNA and protein expression in human neuroblastoma cell lines and primary tissue. Free Radic Biol Med. 2014 Apr; 69:167-71. PMID: 24486338.
        View in: PubMed
      13. Williams RT, Yu A, Diccianni MB, Theodorakis EA, Batova A. Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy. J Exp Clin Cancer Res. 2013; 32(1):57. PMID: 23958461.
        View in: PubMed
      14. Kreissman SG, Seeger RC, Matthay KK, London WB, Sposto R, Grupp SA, Haas-Kogan DA, Laquaglia MP, Yu A, Diller L, Buxton A, Park JR, Cohn SL, Maris JM, Reynolds CP, Villablanca JG. Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomised phase 3 trial. Lancet Oncol. 2013 Sep; 14(10):999-1008. PMID: 23890779.
        View in: PubMed
      15. Chang WW, Lin RJ, Yu J, Chang WY, Fu CH, Lai A, Yu JC, Yu A. The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stem/progenitors. Breast Cancer Res. 2013; 15(3):R39. PMID: 23663564; PMCID: PMC3706809.
      16. Chan YT, Lin YC, Lin RJ, Kuo HH, Thang WC, Chiu KP, Yu A. Concordant and discordant regulation of target genes by miR-31 and its isoforms. PLoS One. 2013; 8(3):e58169. PMID: 23472152.
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      17. Unguru Y, Joffe S, Fernandez CV, Yu A. Ethical issues for control-arm patients after revelation of benefits of experimental therapy: a framework modeled in neuroblastoma. J Clin Oncol. 2013 Feb 10; 31(5):641-6. PMID: 23295797.
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      18. Hsieh MH, Hung JT, Liw YW, Lu YJ, Wong CH, Yu A, Liang PH. Synthesis and evaluation of acyl-chain- and galactose-6''-modified analogues of a-GalCer for NKT cell activation. Chembiochem. 2012 Jul 23; 13(11):1689-97. PMID: 22730199.
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      19. Matthay KK, George RE, Yu A. Promising therapeutic targets in neuroblastoma. Clin Cancer Res. 2012 May 15; 18(10):2740-53. PMID: 22589483.
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      20. Wu TN, Lin KH, Chang YJ, Huang JR, Cheng JY, Yu A, Wong CH. Avidity of CD1d-ligand-receptor ternary complex contributes to T-helper 1 (Th1) polarization and anticancer efficacy. Proc Natl Acad Sci U S A. 2011 Oct 18; 108(42):17275-80. PMID: 21987790.
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      21. Guizzunti G, Theodorakis EA, Yu A, Zurzolo C, Batova A. Cluvenone induces apoptosis via a direct target in mitochondria: a possible mechanism to circumvent chemo-resistance? Invest New Drugs. 2012 Oct; 30(5):1841-8. PMID: 21898184.
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      22. Liang YJ, Kuo HH, Lin CH, Chen YY, Yang BC, Cheng YY, Yu A, Khoo KH, Yu J. Switching of the core structures of glycosphingolipids from globo- and lacto- to ganglio-series upon human embryonic stem cell differentiation. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22564-9. PMID: 21149694.
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      23. Yu A, Gilman AL, Ozkaynak MF, London WB, Kreissman SG, Chen HX, Smith M, Anderson B, Villablanca JG, Matthay KK, Shimada H, Grupp SA, Seeger R, Reynolds CP, Buxton A, Reisfeld RA, Gillies SD, Cohn SL, Maris JM, Sondel PM. Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. N Engl J Med. 2010 Sep 30; 363(14):1324-34. PMID: 20879881.
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      24. Batova A, Altomare D, Chantarasriwong O, Ohlsen KL, Creek KE, Lin YC, Messersmith A, Yu A, Yu J, Theodorakis EA. The synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity. Mol Cancer Ther. 2010 Nov; 9(11):2869-78. PMID: 20881270.
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      25. Lin RJ, Lin YC, Chen J, Kuo HH, Chen YY, Diccianni MB, London WB, Chang CH, Yu A. microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastoma. Cancer Res. 2010 Oct 15; 70(20):7841-50. PMID: 20805302.
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      26. Lin RJ, Lin YC, Yu A. miR-149* induces apoptosis by inhibiting Akt1 and E2F1 in human cancer cells. Mol Carcinog. 2010 Aug; 49(8):719-27. PMID: 20623644.
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      27. Lai CY, Hung JT, Lin HH, Yu A, Chen SH, Tsai YC, Shao LE, Yang WB, Yu J. Immunomodulatory and adjuvant activities of a polysaccharide extract of Ganoderma lucidum in vivo and in vitro. Vaccine. 2010 Jul 12; 28(31):4945-54. PMID: 20653103.
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      28. Yu A, Birke K, Moriniere J, Welge-Lüssen U. TGF-{beta}2 induces senescence-associated changes in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2010 Nov; 51(11):5718-23. PMID: 20554622.
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      29. Sorkin LS, Otto M, Baldwin WM, Vail E, Gillies SD, Handgretinger R, Barfield RC, Ming Yu H, Yu A. Anti-GD(2) with an FC point mutation reduces complement fixation and decreases antibody-induced allodynia. Pain. 2010 Apr; 149(1):135-42. PMID: 20171010.
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      30. Angiolillo AL, Yu A, Reaman G, Ingle AM, Secola R, Adamson PC. A phase II study of Campath-1H in children with relapsed or refractory acute lymphoblastic leukemia: a Children's Oncology Group report. Pediatr Blood Cancer. 2009 Dec; 53(6):978-83. PMID: 19637330.
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      31. Lo TC, Barnhill LM, Kim Y, Nakae EA, Yu A, Diccianni MB. Inactivation of SHIP1 in T-cell acute lymphoblastic leukemia due to mutation and extensive alternative splicing. Leuk Res. 2009 Nov; 33(11):1562-6. PMID: 19473701.
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      32. Yu A, Fuchshofer R, Kook D, Kampik A, Bloemendal H, Welge-Lüssen U. Subtoxic oxidative stress induces senescence in retinal pigment epithelial cells via TGF-beta release. Invest Ophthalmol Vis Sci. 2009 Feb; 50(2):926-35. PMID: 19171648.
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      33. Lee CH, Chou TC, Su TL, Yu J, Shao LE, Yu A. BO-0742, a derivative of AHMA and N-mustard, has selective toxicity to drug sensitive and drug resistant leukemia cells and solid tumors. Cancer Lett. 2009 Apr 18; 276(2):204-11. PMID: 19108949.
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      34. Gilman AL, Ozkaynak MF, Matthay KK, Krailo M, Yu A, Gan J, Sternberg A, Hank JA, Seeger R, Reaman GH, Sondel PM. Phase I study of ch14.18 with granulocyte-macrophage colony-stimulating factor and interleukin-2 in children with neuroblastoma after autologous bone marrow transplantation or stem-cell rescue: a report from the Children's Oncology Group. J Clin Oncol. 2009 Jan 1; 27(1):85-91. PMID: 19047298.
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      35. Huggins R, Li LH, Lin YC, Yu A, Yang HC. Nonparametric estimation of LOH using Affymetrix SNP genotyping arrays for unpaired samples. J Hum Genet. 2008; 53(11-12):983-90. PMID: 18989737.
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      36. Yu A, Moriniere J, Birke M, Neumann C, Fuchshofer R, Kampik A, Bloemendal H, Welge-Lussen U. Reactivation of optic nerve head astrocytes by TGF-beta2 and H2O2 is accompanied by increased Hsp32 and Hsp47 expression. Invest Ophthalmol Vis Sci. 2009 Apr; 50(4):1707-17. PMID: 18952926.
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      37. Chang WW, Lee CH, Lee P, Lin J, Hsu CW, Hung JT, Lin JJ, Yu JC, Shao LE, Yu J, Wong CH, Yu A. Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis. Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33):11667-72. PMID: 18685093.
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      38. Lin YC, Kuo MW, Yu J, Kuo HH, Lin RJ, Lo WL, Yu A. c-Myb is an evolutionary conserved miR-150 target and miR-150/c-Myb interaction is important for embryonic development. Mol Biol Evol. 2008 Oct; 25(10):2189-98. PMID: 18667440.
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      39. Yu A, Fuchshofer R, Birke M, Kampik A, Bloemendal H, Welge-Lüssen U. Oxidative stress and TGF-beta2 increase heat shock protein 27 expression in human optic nerve head astrocytes. Invest Ophthalmol Vis Sci. 2008 Dec; 49(12):5403-11. PMID: 18552392.
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      40. Yang HC, Huang MC, Li LH, Lin CH, Yu A, Diccianni MB, Wu JY, Chen YT, Fann CS. MPDA: microarray pooled DNA analyzer. BMC Bioinformatics. 2008; 9:196. PMID: 18412951.
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      41. Lin YC, Hsieh LC, Kuo MW, Yu J, Kuo HH, Lo WL, Lin RJ, Yu A, Li WH. Human TRIM71 and its nematode homologue are targets of let-7 microRNA and its zebrafish orthologue is essential for development. Mol Biol Evol. 2007 Nov; 24(11):2525-34. PMID: 17890240.
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      42. Batova A, Lam T, Wascholowski V, Yu A, Giannis A, Theodorakis EA. Synthesis and evaluation of caged Garcinia xanthones. Org Biomol Chem. 2007 Feb 7; 5(3):494-500. PMID: 17252132.
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      43. Ling TY, Kuo MD, Li CL, Yu A, Huang YH, Wu TJ, Lin YC, Chen SH, Yu J. Identification of pulmonary Oct-4+ stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro. Proc Natl Acad Sci U S A. 2006 Jun 20; 103(25):9530-5. PMID: 16772384.
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      44. Batova A, Cottam H, Yu J, Diccianni MB, Carrera CJ, Yu A. EFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine. Blood. 2006 Feb 1; 107(3):898-903. PMID: 16234352.
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      45. Loh KC, Willert J, Meltzer H, Roberts W, Kerlin B, Kadota R, Levy M, White G, Geddis A, Schiff D, Martin L, Yu A, Kung F, Spear MA. Temozolomide and radiation for aggressive pediatric central nervous system malignancies. J Pediatr Hematol Oncol. 2005 May; 27(5):254-8. PMID: 15891559.
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      46. Gebauer S, Yu A, Omura-Minamisawa M, Batova A, Diccianni MB. Expression profiles and clinical relationships of ID2, CDKN1B, and CDKN2A in primary neuroblastoma. Genes Chromosomes Cancer. 2004 Dec; 41(4):297-308. PMID: 15390183.
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      47. Diccianni MB, Yu J, Meppelink G, de Vries M, Shao L, Gebauer S, Shih H, Roberts W, Kilcoin NP, Pullen J, Carson DA, Yu A. 3-amino thioacridone inhibits DNA synthesis and induce DNA damage in T-cell acute lymphoblastic leukemia (T-ALL) in a p16-dependent manner. J Exp Ther Oncol. 2004 Oct; 4(3):223-37. PMID: 15724842.
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      48. McGowan KA, Nyhan WL, Barshop BA, Naviaux RK, Yu A, Haas RH, Townsend JJ. The role of methionine in ethylmalonic encephalopathy with petechiae. Arch Neurol. 2004 Apr; 61(4):570-4. PMID: 15096407.
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      49. Houghton PJ, Adamson PC, Blaney S, Fine HA, Gorlick R, Haber M, Helman L, Hirschfeld S, Hollingshead MG, Israel MA, Lock RB, Maris JM, Merlino G, Patterson W, Reynolds CP, Shannon K, Yu A, Yu J, Smith MA. Testing of new agents in childhood cancer preclinical models: meeting summary. Clin Cancer Res. 2002 Dec; 8(12):3646-57. PMID: 12473573.
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      50. Batova A, Shao LE, Diccianni MB, Yu A, Tanaka T, Rephaeli A, Nudelman A, Yu J. The histone deacetylase inhibitor AN-9 has selective toxicity to acute leukemia and drug-resistant primary leukemia and cancer cell lines. Blood. 2002 Nov 1; 100(9):3319-24. PMID: 12384433.
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      51. Kletzel M, Katzenstein HM, Haut PR, Yu A, Morgan E, Reynolds M, Geissler G, Marymount MH, Liu D, Kalapurakal JA, Shore RM, Bardo DM, Schmoldt J, Rademaker AW, Cohn SL. Treatment of high-risk neuroblastoma with triple-tandem high-dose therapy and stem-cell rescue: results of the Chicago Pilot II Study. J Clin Oncol. 2002 May 1; 20(9):2284-92. PMID: 11980999.
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      52. Sorkin LS, Yu A, Junger H, Doom CM. Antibody directed against GD(2) produces mechanical allodynia, but not thermal hyperalgesia when administered systemically or intrathecally despite its dependence on capsaicin sensitive afferents. Brain Res. 2002 Mar 15; 930(1-2):67-74. PMID: 11879797.
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      53. Broome HE, Yu A, Diccianni M, Camitta BM, Monia BP, Dean NM. Inhibition of Bcl-xL expression sensitizes T-cell acute lymphoblastic leukemia cells to chemotherapeutic drugs. Leuk Res. 2002 Mar; 26(3):311-6. PMID: 11792421.
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      54. Omura-Minamisawa M, Diccianni MB, Chang RC, Batova A, Bridgeman LJ, Schiff J, Cohn SL, London WB, Yu A. p16/p14(ARF) cell cycle regulatory pathways in primary neuroblastoma: p16 expression is associated with advanced stage disease. Clin Cancer Res. 2001 Nov; 7(11):3481-90. PMID: 11705866.
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      55. Omura-Minamisawa M, Diccianni MB, Batova A, Chang RC, Bridgeman LJ, Yu J, de Wit E, Kung FH, Pullen JD, Yu A. In vitro sensitivity of T-cell lymphoblastic leukemia to UCN-01 (7-hydroxystaurosporine) is dependent on p16 protein status: a Pediatric Oncology Group study. Cancer Res. 2000 Dec 1; 60(23):6573-6. PMID: 11118035.
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      56. von Lintig FC, Huvar I, Law P, Diccianni MB, Yu A, Boss GR. Ras activation in normal white blood cells and childhood acute lymphoblastic leukemia. Clin Cancer Res. 2000 May; 6(5):1804-10. PMID: 10815901.
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      57. Omura-Minamisawa M, Diccianni MB, Batova A, Chang RC, Bridgeman LJ, Yu J, Pullen J, Bowman WP, Yu A. Universal inactivation of both p16 and p15 but not downstream components is an essential event in the pathogenesis of T-cell acute lymphoblastic leukemia. Clin Cancer Res. 2000 Apr; 6(4):1219-28. PMID: 10778944.
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      58. Batova A, Kamps A, Gillies SD, Reisfeld RA, Yu A. The Ch14.18-GM-CSF fusion protein is effective at mediating antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity in vitro. Clin Cancer Res. 1999 Dec; 5(12):4259-63. PMID: 10632368.
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      59. Batova A, Diccianni MB, Omura-Minamisawa M, Yu J, Carrera CJ, Bridgeman LJ, Kung FH, Pullen J, Amylon MD, Yu A. Use of alanosine as a methylthioadenosine phosphorylase-selective therapy for T-cell acute lymphoblastic leukemia in vitro. Cancer Res. 1999 Apr 1; 59(7):1492-7. PMID: 10197619.
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      60. Diccianni MB, Omura-Minamisawa M, Batova A, Le T, Bridgeman L, Yu A. Frequent deregulation of p16 and the p16/G1 cell cycle-regulatory pathway in neuroblastoma. Int J Cancer. 1999 Jan 5; 80(1):145-54. PMID: 9935245.
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      61. Yu A, Uttenreuther-Fischer MM, Huang CS, Tsui CC, Gillies SD, Reisfeld RA, Kung FH. Phase I trial of a human-mouse chimeric anti-disialoganglioside monoclonal antibody ch14.18 in patients with refractory neuroblastoma and osteosarcoma. J Clin Oncol. 1998 Jun; 16(6):2169-80. PMID: 9626218.
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      62. Diccianni MB, Batova A, Yu J, Vu T, Pullen J, Amylon M, Pollock BH, Yu A. Shortened survival after relapse in T-cell acute lymphoblastic leukemia patients with p16/p15 deletions. Leuk Res. 1997 Jun; 21(6):549-58. PMID: 9279366.
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      63. Batova A, Diccianni MB, Yu JC, Nobori T, Link MP, Pullen J, Yu A. Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia. Cancer Res. 1997 Mar 1; 57(5):832-6. PMID: 9041181.
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      64. Burns JC, Yee JK, Yu A. Methods for producing high titer, pantropic retroviral vectors for gene transfer into leukemic T-cells. Methods Mol Med. 1997; 7:213-21. PMID: 24493429.
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      65. Xiao WH, Yu A, Sorkin LS. Electrophysiological characteristics of primary afferent fibers after systemic administration of anti-GD2 ganglioside antibody. Pain. 1997 Jan; 69(1-2):145-51. PMID: 9060025.
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      66. Batova A, Diccianni MB, Nobori T, Vu T, Yu J, Bridgeman L, Yu A. Frequent deletion in the methylthioadenosine phosphorylase gene in T-cell acute lymphoblastic leukemia: strategies for enzyme-targeted therapy. Blood. 1996 Oct 15; 88(8):3083-90. PMID: 8874207.
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      67. Diccianni MB, Chau LS, Batova A, Vu TQ, Yu A. The p16 and p18 tumor suppressor genes in neuroblastoma: implications for drug resistance. Cancer Lett. 1996 Jul 12; 104(2):183-92. PMID: 8665486.
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      68. Nobori T, Takabayashi K, Tran P, Orvis L, Batova A, Yu A, Carson DA. Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers. Proc Natl Acad Sci U S A. 1996 Jun 11; 93(12):6203-8. PMID: 8650244.
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      69. Diccianni MB, Yu J, Hsiao M, Mukherjee S, Shao LE, Yu A. Clinical significance of p53 mutations in relapsed T-cell acute lymphoblastic leukemia. Blood. 1994 Nov 1; 84(9):3105-12. PMID: 7949183.
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      70. Hsiao MH, Yu A, Yeargin J, Ku D, Haas M. Nonhereditary p53 mutations in T-cell acute lymphoblastic leukemia are associated with the relapse phase. Blood. 1994 May 15; 83(10):2922-30. PMID: 8180387.
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      71. Page T, Barshop B, Yu A, Nyhan WL. Treatment of Lesch-Nyhan syndrome with AICAR. Adv Exp Med Biol. 1994; 370:353-6. PMID: 7660927.
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      72. Yeargin J, Cheng J, Yu A, Gjerset R, Bogart M, Haas M. P53 mutation in acute T cell lymphoblastic leukemia is of somatic origin and is stable during establishment of T cell acute lymphoblastic leukemia cell lines. J Clin Invest. 1993 May; 91(5):2111-7. PMID: 8486778.
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      73. Page T, Nyhan WL, Yu A, Yu J. A syndrome of megaloblastic anemia, immunodeficiency, and excessive nucleotide degradation. Adv Exp Med Biol. 1991; 309B:345-8. PMID: 1781393.
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      74. Hsiao RJ, Seeger RC, Yu A, O'Connor DT. Chromogranin A in children with neuroblastoma. Serum concentration parallels disease stage and predicts survival. J Clin Invest. 1990 May; 85(5):1555-9. PMID: 2332506.
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      75. Matsumoto SS, Yu J, Yu A. The effect of deoxyadenosine plus deoxycoformycin on replicative and repair synthesis of DNA in human lymphoblasts and isolated nuclei. J Biol Chem. 1988 May 25; 263(15):7153-8. PMID: 3259231.
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