Alice Yu

Title(s)Recall Faculty, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Predicting toxicity and success of anti-GD2 immunotherapy of neuroblastoma
    NIH R01CA164132Apr 1, 2012 - Mar 31, 2016
    Role: Principal Investigator
    IMMUNE MONITOR FOR COG TRIAL OF ANTI-GD2 IN NEUROBLASTOMA
    NIH R01FD002319Sep 30, 2003 - May 31, 2010
    Role: Principal Investigator
    CLINICAL TRIAL OF ANTIID VACCINE FOR NEUROBLASTOMA
    NIH R21CA078806Jul 1, 1998 - Jun 30, 2000
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000827Jan 27, 1997 - Nov 30, 2010
    Role: Co-Investigator
    EXPLOITATION OF FREQUENT P16 DELETION IN T-ALL THERAPY
    NIH R21CA070397Apr 1, 1996 - Mar 31, 1998
    Role: Principal Investigator
    CLINICAL UTILITY OF A NEUROBLASTOMA MONOCLONAL ANTIBODY
    NIH R01CA040186Sep 1, 1985 - Nov 30, 1988
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. BTK Inhibition Reverses MDSC-Mediated Immunosuppression and Enhances Response to Anti-PDL1 Therapy in Neuroblastoma. Cancers (Basel). 2021 Feb 16; 13(4). Ishfaq M, Pham T, Beaman C, Tamayo P, Yu AL, Joshi S. PMID: 33669187.
      View in: PubMed   Mentions:
    2. Long-Term Follow-up of a Phase III Study of ch14.18 (Dinutuximab) + Cytokine Immunotherapy in Children with High-Risk Neuroblastoma: COG Study ANBL0032. Clin Cancer Res. 2021 Apr 15; 27(8):2179-2189. Yu AL, Gilman AL, Ozkaynak MF, Naranjo A, Diccianni MB, Gan J, Hank JA, Batova A, London WB, Tenney SC, Smith M, Shulkin BL, Parisi M, Matthay KK, Cohn SL, Maris JM, Bagatell R, Park JR, Sondel PM. PMID: 33504555.
      View in: PubMed   Mentions: 6     Fields:    
    3. High B3GALT5 expression confers poor clinical outcome and contributes to tumor progression and metastasis in breast cancer. Breast Cancer Res. 2021 Jan 07; 23(1):5. Liao YM, Wang YH, Hung JT, Lin YJ, Huang YL, Liao GS, Hsu YL, Wu JC, Yu AL. PMID: 33413566.
      View in: PubMed   Mentions:    Fields:    
    4. Sialylation of CD55 by ST3GAL1 Facilitates Immune Evasion in Cancer. Cancer Immunol Res. 2021 01; 9(1):113-122. Lin WD, Fan TC, Hung JT, Yeo HL, Wang SH, Kuo CW, Khoo KH, Pai LM, Yu J, Yu AL. PMID: 33177111.
      View in: PubMed   Mentions: 1     Fields:    
    5. Co-Delivery of CPT-11 and Panobinostat with Anti-GD2 Antibody Conjugated Immunoliposomes for Targeted Combination Chemotherapy. Cancers (Basel). 2020 Oct 31; 12(11). Jose G, Lu YJ, Hung JT, Yu AL, Chen JP. PMID: 33142721.
      View in: PubMed   Mentions:
    6. Targeting glycosphingolipids for cancer immunotherapy. FEBS Lett. 2020 11; 594(22):3602-3618. Yu J, Hung JT, Wang SH, Cheng JY, Yu AL. PMID: 32860713.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Comprehensive Cohort Analysis of Mutational Spectrum in Early Onset Breast Cancer Patients. Cancers (Basel). 2020 Jul 28; 12(8). Midha MK, Huang YF, Yang HH, Fan TC, Chang NC, Chen TH, Wang YT, Kuo WH, Chang KJ, Shen CY, Yu AL, Chiu KP, Chen CJ. PMID: 32731431.
      View in: PubMed   Mentions:
    8. Anti-GD2 induced allodynia in rats can be reduced by pretreatment with DFMO. PLoS One. 2020; 15(7):e0236115. Diccianni MB, Kempinska K, Gangoti JA, Yu AL, Sorkin LS. PMID: 32697811.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    9. Globo H-KLH vaccine adagloxad simolenin (OBI-822)/OBI-821 in patients with metastatic breast cancer: phase II randomized, placebo-controlled study. J Immunother Cancer. 2020 07; 8(2). Huang CS, Yu AL, Tseng LM, Chow LWC, Hou MF, Hurvitz SA, Schwab RB, L Murray J, Chang HK, Chang HT, Chen SC, Kim SB, Hung JT, Ueng SH, Lee SH, Chen CC, Rugo HS. PMID: 32718986.
      View in: PubMed   Mentions: 1     Fields:    
    10. Irinotecan, Temozolomide, and Dinutuximab With GM-CSF in Children With Refractory or Relapsed Neuroblastoma: A Report From the Children's Oncology Group. J Clin Oncol. 2020 07 01; 38(19):2160-2169. Mody R, Yu AL, Naranjo A, Zhang FF, London WB, Shulkin BL, Parisi MT, Servaes SE, Diccianni MB, Hank JA, Felder M, Birstler J, Sondel PM, Asgharzadeh S, Glade-Bender J, Katzenstein H, Maris JM, Park JR, Bagatell R. PMID: 32343642.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    11. Design and synthesis of glyco-peptides as anti-cancer agents targeting thrombin-protease activated receptor-1 interaction. Chem Commun (Camb). 2020 May 28; 56(43):5827-5830. Chang YH, Wu JC, Yu HM, Hsu HT, Wu YT, Yu AL, Yu CT, Wong CH. PMID: 32329494.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    12. Upregulation of Protein Synthesis and Proteasome Degradation Confers Sensitivity to Proteasome Inhibitor Bortezomib in Myc-Atypical Teratoid/Rhabdoid Tumors. Cancers (Basel). 2020 Mar 22; 12(3). Tran HM, Wu KS, Sung SY, Changou CA, Hsieh TH, Liu YR, Liu YL, Tsai ML, Lee HL, Hsieh KL, Huang WC, Liang ML, Chen HH, Lee YY, Lin SC, Ho DM, Chang FC, Chao ME, Chen W, Chu SS, Yu AL, Yen Y, Chang CC, Wong TT. PMID: 32235770.
      View in: PubMed   Mentions:
    13. Molecular-Clinical Correlation in Pediatric Medulloblastoma: A Cohort Series Study of 52 Cases in Taiwan. Cancers (Basel). 2020 Mar 11; 12(3). Wu KS, Ho DM, Jou ST, Yu AL, Tran HM, Liang ML, Chen HH, Lee YY, Chen YW, Lin SC, Chang FC, Tsai ML, Liu YL, Lee HL, Hsieh KL, Huang WC, Sung SY, Chang CC, Changou CA, Liang KH, Hsieh TH, Liu YR, Chao ME, Chen W, Chu SS, Cho EC, Wong TT. PMID: 32168907.
      View in: PubMed   Mentions:
    14. A Phase II Trial of Hu14.18K322A in Combination with Induction Chemotherapy in Children with Newly Diagnosed High-Risk Neuroblastoma. Clin Cancer Res. 2019 11 01; 25(21):6320-6328. Furman WL, Federico SM, McCarville MB, Shulkin BL, Davidoff AM, Krasin MJ, Sahr N, Sykes A, Wu J, Brennan RC, Bishop MW, Helmig S, Stewart E, Navid F, Triplett B, Santana VM, Bahrami A, Anthony G, Yu AL, Hank J, Gillies SD, Sondel PM, Leung WH, Pappo AS. PMID: 31601569.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsCTClinical Trials
    15. GPER-induced signaling is essential for the survival of breast cancer stem cells. Int J Cancer. 2020 03 15; 146(6):1674-1685. Chan YT, Lai AC, Lin RJ, Wang YH, Wang YT, Chang WW, Wu HY, Lin YJ, Chang WY, Wu JC, Yu JC, Chen YJ, Yu AL. PMID: 31340060.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    16. Application of cell-free DNA sequencing in characterization of bloodborne microbes and the study of microbe-disease interactions. PeerJ. 2019; 7:e7426. Chiu KP, Yu AL. PMID: 31404440.
      View in: PubMed   Mentions:
    17. FAM129B, an antioxidative protein, reduces chemosensitivity by competing with Nrf2 for Keap1 binding. EBioMedicine. 2019 Jul; 45:25-38. Cheng KC, Lin RJ, Cheng JY, Wang SH, Yu JC, Wu JC, Liang YJ, Hsu HM, Yu J, Yu AL. PMID: 31262713.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    18. Sialylation of vasorin by ST3Gal1 facilitates TGF-ß1-mediated tumor angiogenesis and progression. Int J Cancer. 2019 04 15; 144(8):1996-2007. Yeo HL, Fan TC, Lin RJ, Yu JC, Liao GS, Chen ES, Ho MY, Lin WD, Chen K, Chen CH, Hung JT, Wu JC, Chang NC, Chang MD, Yu J, Yu AL. PMID: 30252131.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    19. Reciprocal feedback regulation of ST3GAL1 and GFRA1 signaling in breast cancer cells. Cancer Lett. 2018 10 10; 434:184-195. Fan TC, Yeo HL, Hsu HM, Yu JC, Ho MY, Lin WD, Chang NC, Yu J, Yu AL. PMID: 30040982.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    20. Corrigendum: A Comprehensive Safety Trial of Chimeric Antibody 14.18 With GM-CSF, IL-2, and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy: Children's Oncology Group Study ANBL0931. Front Immunol. 2018; 9:1641. Ozkaynak MF, Gilman AL, London WB, Naranjo A, Diccianni MB, Tenney SC, Smith M, Messer KS, Seeger R, Reynolds CP, Smith LM, Shulkin BL, Parisi M, Maris JM, Park JR, Sondel PM, Yu AL. PMID: 30046297.
      View in: PubMed   Mentions: 3     Fields:    
    21. A Comprehensive Safety Trial of Chimeric Antibody 14.18 With GM-CSF, IL-2, and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy: Children's Oncology Group Study ANBL0931. Front Immunol. 2018; 9:1355. Ozkaynak MF, Gilman AL, London WB, Naranjo A, Diccianni MB, Tenney SC, Smith M, Messer KS, Seeger R, Reynolds CP, Smith LM, Shulkin BL, Parisi M, Maris JM, Park JR, Sondel PM, Yu AL. PMID: 29967609.
      View in: PubMed   Mentions: 20     Fields:    
    22. Analysis of microbial sequences in plasma cell-free DNA for early-onset breast cancer patients and healthy females. BMC Med Genomics. 2018 02 13; 11(Suppl 1):16. Huang YF, Chen YJ, Fan TC, Chang NC, Chen YJ, Midha MK, Chen TH, Yang HH, Wang YT, Yu AL, Chiu KP. PMID: 29504912.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. RETRACTED: Deficiency of a novel gene, Yulink, predisposes to heart failure and ventricular arrhythmia. FASEB J. 2018 Jan 11; fj201700932RR. Tsai CT, Kuo MW, Lin JL, Yu AL, Yu J. PMID: 29401584.
      View in: PubMed   Mentions:    Fields:    
    24. Neuroblastoma Patients' KIR and KIR-Ligand Genotypes Influence Clinical Outcome for Dinutuximab-based Immunotherapy: A Report from the Children's Oncology Group. Clin Cancer Res. 2018 01 01; 24(1):189-196. Erbe AK, Wang W, Carmichael L, Kim K, Mendonça EA, Song Y, Hess D, Reville PK, London WB, Naranjo A, Hank JA, Diccianni MB, Reisfeld RA, Gillies SD, Matthay KK, Cohn SL, Hogarty MD, Maris JM, Park JR, Ozkaynak MF, Gilman AL, Yu AL, Sondel PM. PMID: 28972044.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    25. High expression FUT1 and B3GALT5 is an independent predictor of postoperative recurrence and survival in hepatocellular carcinoma. Sci Rep. 2017 09 07; 7(1):10750. Kuo HH, Lin RJ, Hung JT, Hsieh CB, Hung TH, Lo FY, Ho MY, Yeh CT, Huang YL, Yu J, Yu AL. PMID: 28883415.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    26. HLA-Bw4-I-80 Isoform Differentially Influences Clinical Outcome As Compared to HLA-Bw4-T-80 and HLA-A-Bw4 Isoforms in Rituximab or Dinutuximab-Based Cancer Immunotherapy. Front Immunol. 2017; 8:675. Erbe AK, Wang W, Reville PK, Carmichael L, Kim K, Mendonca EA, Song Y, Hank JA, London WB, Naranjo A, Hong F, Hogarty MD, Maris JM, Park JR, Ozkaynak MF, Miller JS, Gilman AL, Kahl B, Yu AL, Sondel PM. PMID: 28659916.
      View in: PubMed   Mentions: 8     Fields:    
    27. Irinotecan-temozolomide with temsirolimus or dinutuximab in children with refractory or relapsed neuroblastoma (COG ANBL1221): an open-label, randomised, phase 2 trial. Lancet Oncol. 2017 07; 18(7):946-957. Mody R, Naranjo A, Van Ryn C, Yu AL, London WB, Shulkin BL, Parisi MT, Servaes SE, Diccianni MB, Sondel PM, Bender JG, Maris JM, Park JR, Bagatell R. PMID: 28549783.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCTClinical Trials
    28. Englerin A induces an acute inflammatory response and reveals lipid metabolism and ER stress as targetable vulnerabilities in renal cell carcinoma. PLoS One. 2017; 12(3):e0172632. Batova A, Altomare D, Creek KE, Naviaux RK, Wang L, Li K, Green E, Williams R, Naviaux JC, Diccianni M, Yu AL. PMID: 28296891.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    29. Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation. ACS Chem Biol. 2016 12 16; 11(12):3431-3441. Wu TN, Lin KH, Wu YT, Huang JR, Hung JT, Wu JC, Chen CY, Chu KC, Lin NH, Yu AL, Wong CH. PMID: 27782396.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    30. Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells. Cell Death Dis. 2016 08 25; 7(8):e2347. Tan KP, Ho MY, Cho HC, Yu J, Hung JT, Yu AL. PMID: 27560716.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    31. Evidence for a common evolutionary rate in metazoan transcriptional networks. Elife. 2015 Dec 18; 4. Carvunis AR, Wang T, Skola D, Yu A, Chen J, Kreisberg JF, Ideker T. PMID: 26682651.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    32. Tracking and Finding Slow-Proliferating/Quiescent Cancer Stem Cells with Fluorescent Nanodiamonds. Small. 2015 Sep 09; 11(34):4394-402. Lin HH, Lee HW, Lin RJ, Huang CW, Liao YC, Chen YT, Fang JM, Lee TC, Yu AL, Chang HC. PMID: 26077637.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    33. A simple and low-cost platform technology for producing pexiganan antimicrobial peptide in E. coli. Biotechnol Bioeng. 2015 May; 112(5):957-64. Zhao CX, Dwyer MD, Yu AL, Wu Y, Fang S, Middelberg AP. PMID: 25425208.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    34. Erratum: renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy. J Exp Clin Cancer Res. 2014 Dec 05; 33:95. Williams RT, Yu AL, Diccianni MB, Theodorakis EA, Batova A. PMID: 25480670.
      View in: PubMed   Mentions:    Fields:    
    35. Metabolic characteristics of 13-cis-retinoic acid (isotretinoin) and anti-tumour activity of the 13-cis-retinoic acid metabolite 4-oxo-13-cis-retinoic acid in neuroblastoma. Br J Pharmacol. 2014 Dec; 171(23):5330-44. Sonawane P, Cho HE, Tagde A, Verlekar D, Yu AL, Reynolds CP, Kang MH. PMID: 25039756.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    36. Globo-H ceramide shed from cancer cells triggers translin-associated factor X-dependent angiogenesis. Cancer Res. 2014 Dec 01; 74(23):6856-66. Cheng JY, Wang SH, Lin J, Tsai YC, Yu J, Wu JC, Hung JT, Lin JJ, Wu YY, Yeh KT, Yu AL. PMID: 25281721.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    37. The prognostic significance of RUNX2 and miR-10a/10b and their inter-relationship in breast cancer. J Transl Med. 2014 Sep 30; 12:257. Chang CH, Fan TC, Yu JC, Liao GS, Lin YC, Shih AC, Li WH, Yu AL. PMID: 25266482.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    38. A novel oncogenic role of inositol phosphatase SHIP2 in ER-negative breast cancer stem cells: involvement of JNK/vimentin activation. Stem Cells. 2014 Aug; 32(8):2048-60. Fu CH, Lin RJ, Yu J, Chang WW, Liao GS, Chang WY, Tseng LM, Tsai YF, Yu JC, Yu AL. PMID: 24802135.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    39. High expression of CAI2, a 9p21-embedded long noncoding RNA, contributes to advanced-stage neuroblastoma. Cancer Res. 2014 Jul 15; 74(14):3753-63. Barnhill LM, Williams RT, Cohen O, Kim Y, Batova A, Mielke JA, Messer K, Pu M, Bao L, Yu AL, Diccianni MB. PMID: 25028366.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    40. Potent adjuvant effects of novel NKT stimulatory glycolipids on hemagglutinin based DNA vaccine for H5N1 influenza virus. Antiviral Res. 2014 Jul; 107:110-8. Hung JT, Tsai YC, Lin WD, Jan JT, Lin KH, Huang JR, Cheng JY, Chen MW, Wong CH, Yu AL. PMID: 24786174.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    41. The multifaceted effects of polysaccharides isolated from Dendrobium huoshanense on immune functions with the induction of interleukin-1 receptor antagonist (IL-1ra) in monocytes. PLoS One. 2014; 9(4):e94040. Lin J, Chang YJ, Yang WB, Yu AL, Wong CH. PMID: 24705413.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    42. Chimeric antibody c.8B6 to O-acetyl-GD2 mediates the same efficient anti-neuroblastoma effects as therapeutic ch14.18 antibody to GD2 without antibody induced allodynia. PLoS One. 2014; 9(2):e87210. Terme M, Dorvillius M, Cochonneau D, Chaumette T, Xiao W, Diccianni MB, Barbet J, Yu AL, Paris F, Sorkin LS, Birklé S. PMID: 24520328.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    43. Chimeras of p14ARF and p16: functional hybrids with the ability to arrest growth. PLoS One. 2014; 9(2):e88219. Williams RT, Barnhill LM, Kuo HH, Lin WD, Batova A, Yu AL, Diccianni MB. PMID: 24505435.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    44. Absence of MGST1 mRNA and protein expression in human neuroblastoma cell lines and primary tissue. Free Radic Biol Med. 2014 Apr; 69:167-71. Kelner MJ, Diccianni MB, Yu AL, Rutherford MR, Estes LA, Morgenstern R. PMID: 24486338.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    45. a-Galactosylceramide but not phenyl-glycolipids induced NKT cell anergy and IL-33-mediated myeloid-derived suppressor cell accumulation via upregulation of egr2/3. J Immunol. 2014 Feb 15; 192(4):1972-81. Huang JR, Tsai YC, Chang YJ, Wu JC, Hung JT, Lin KH, Wong CH, Yu AL. PMID: 24465013.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    46. Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. PLoS One. 2013; 8(12):e82751. Chen YJ, Thang MW, Chan YT, Huang YF, Ma N, Yu AL, Wu CY, Hu ML, Chiu KP. PMID: 24358224.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    47. Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy. J Exp Clin Cancer Res. 2013 Aug 20; 32:57. Williams RT, Yu AL, Diccianni MB, Theodorakis EA, Batova A. PMID: 23958461.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    48. Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomised phase 3 trial. Lancet Oncol. 2013 Sep; 14(10):999-1008. Kreissman SG, Seeger RC, Matthay KK, London WB, Sposto R, Grupp SA, Haas-Kogan DA, Laquaglia MP, Yu AL, Diller L, Buxton A, Park JR, Cohn SL, Maris JM, Reynolds CP, Villablanca JG. PMID: 23890779.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCTClinical Trials
    49. Concordant and discordant regulation of target genes by miR-31 and its isoforms. PLoS One. 2013; 8(3):e58169. Chan YT, Lin YC, Lin RJ, Kuo HH, Thang WC, Chiu KP, Yu AL. PMID: 23472152.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    50. Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer. Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7):2517-22. Huang YL, Hung JT, Cheung SK, Lee HY, Chu KC, Li ST, Lin YC, Ren CT, Cheng TJ, Hsu TL, Yu AL, Wu CY, Wong CH. PMID: 23355685.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    51. Ethical issues for control-arm patients after revelation of benefits of experimental therapy: a framework modeled in neuroblastoma. J Clin Oncol. 2013 Feb 10; 31(5):641-6. Unguru Y, Joffe S, Fernandez CV, Yu AL. PMID: 23295797.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    52. Surface markers in stem cells and cancer from the perspective of glycomic analysis. Int J Biol Markers. 2012 Dec 27; 27(4):e344-52. Cho HC, Liao CH, Yu AL, Yu J. PMID: 23250773.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    53. Synthesis and evaluation of acyl-chain- and galactose-6''-modified analogues of a-GalCer for NKT cell activation. Chembiochem. 2012 Jul 23; 13(11):1689-97. Hsieh MH, Hung JT, Liw YW, Lu YJ, Wong CH, Yu AL, Liang PH. PMID: 22730199.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    54. High-speed mass measurement of nanoparticle and virus. Anal Chem. 2012 Jun 05; 84(11):4965-9. Lin HC, Lin JL, Lin HH, Tsai SW, Yu AL, Chen RL, Chen CH. PMID: 22591507.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    55. Promising therapeutic targets in neuroblastoma. Clin Cancer Res. 2012 May 15; 18(10):2740-53. Matthay KK, George RE, Yu AL. PMID: 22589483.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    56. Monoclonal antibodies targeting the synthetic peptide corresponding to the polybasic cleavage site on H5N1 influenza hemagglutinin. J Biomed Sci. 2012 Apr 03; 19:37. Tsai HJ, Chi LA, Yu AL. PMID: 22471562.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    57. Single nuclei Raman spectroscopy for drug evaluation. Anal Chem. 2012 Jan 03; 84(1):113-20. Lin HH, Li YC, Chang CH, Liu C, Yu AL, Chen CH. PMID: 22053782.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    58. Avidity of CD1d-ligand-receptor ternary complex contributes to T-helper 1 (Th1) polarization and anticancer efficacy. Proc Natl Acad Sci U S A. 2011 Oct 18; 108(42):17275-80. Wu TN, Lin KH, Chang YJ, Huang JR, Cheng JY, Yu AL, Wong CH. PMID: 21987790.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    59. Cluvenone induces apoptosis via a direct target in mitochondria: a possible mechanism to circumvent chemo-resistance? Invest New Drugs. 2012 Oct; 30(5):1841-8. Guizzunti G, Theodorakis EA, Yu AL, Zurzolo C, Batova A. PMID: 21898184.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    60. Switching of the core structures of glycosphingolipids from globo- and lacto- to ganglio-series upon human embryonic stem cell differentiation. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22564-9. Liang YJ, Kuo HH, Lin CH, Chen YY, Yang BC, Cheng YY, Yu AL, Khoo KH, Yu J. PMID: 21149694.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    61. Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. N Engl J Med. 2010 Sep 30; 363(14):1324-34. Yu AL, Gilman AL, Ozkaynak MF, London WB, Kreissman SG, Chen HX, Smith M, Anderson B, Villablanca JG, Matthay KK, Shimada H, Grupp SA, Seeger R, Reynolds CP, Buxton A, Reisfeld RA, Gillies SD, Cohn SL, Maris JM, Sondel PM, Children's Oncology Group . PMID: 20879881.
      View in: PubMed   Mentions: 532     Fields:    Translation:Humans
    62. The synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity. . 2010 Nov; 9(11):2869-78. Batova A, Altomare D, Chantarasriwong O, Ohlsen KL, Creek KE, Lin YC, Messersmith A, Yu AL, Yu J, Theodorakis EA. PMID: 20881270.
      View in: PubMed   Mentions:
    63. microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastoma. Cancer Res. 2010 Oct 15; 70(20):7841-50. Lin RJ, Lin YC, Chen J, Kuo HH, Chen YY, Diccianni MB, London WB, Chang CH, Yu AL. PMID: 20805302.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    64. miR-149* induces apoptosis by inhibiting Akt1 and E2F1 in human cancer cells. Mol Carcinog. 2010 Aug; 49(8):719-27. Lin RJ, Lin YC, Yu AL. PMID: 20623644.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    65. Immunomodulatory and adjuvant activities of a polysaccharide extract of Ganoderma lucidum in vivo and in vitro. Vaccine. 2010 Jul 12; 28(31):4945-54. Lai CY, Hung JT, Lin HH, Yu AL, Chen SH, Tsai YC, Shao LE, Yang WB, Yu J. PMID: 20653103.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    66. TGF-{beta}2 induces senescence-associated changes in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2010 Nov; 51(11):5718-23. Yu AL, Birke K, Moriniere J, Welge-Lüssen U. PMID: 20554622.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    67. Quantitative measurement of nano-/microparticle endocytosis by cell mass spectrometry. Angew Chem Int Ed Engl. 2010 May 03; 49(20):3460-4. Lin HC, Lin HH, Kao CY, Yu AL, Peng WP, Chen CH. PMID: 20391551.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    68. Anti-GD(2) with an FC point mutation reduces complement fixation and decreases antibody-induced allodynia. Pain. 2010 Apr; 149(1):135-142. Sorkin LS, Otto M, Baldwin WM, Vail E, Gillies SD, Handgretinger R, Barfield RC, Yu HM, Yu AL. PMID: 20171010.
      View in: PubMed   Mentions: 54     Fields:    Translation:Animals
    69. A phase II study of Campath-1H in children with relapsed or refractory acute lymphoblastic leukemia: a Children's Oncology Group report. Pediatr Blood Cancer. 2009 Dec; 53(6):978-83. Angiolillo AL, Yu AL, Reaman G, Ingle AM, Secola R, Adamson PC. PMID: 19637330.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCTClinical Trials
    70. Inactivation of SHIP1 in T-cell acute lymphoblastic leukemia due to mutation and extensive alternative splicing. Leuk Res. 2009 Nov; 33(11):1562-6. Lo TC, Barnhill LM, Kim Y, Nakae EA, Yu AL, Diccianni MB. PMID: 19473701.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    71. A novel puf-A gene predicted from evolutionary analysis is involved in the development of eyes and primordial germ-cells. PLoS One. 2009; 4(3):e4980. Kuo MW, Wang SH, Chang JC, Chang CH, Huang LJ, Lin HH, Yu AL, Li WH, Yu J. PMID: 19319195.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    72. BO-0742, a derivative of AHMA and N-mustard, has selective toxicity to drug sensitive and drug resistant leukemia cells and solid tumors. Cancer Lett. 2009 Apr 18; 276(2):204-11. Lee CH, Chou TC, Su TL, Yu J, Shao LE, Yu AL. PMID: 19108949.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    73. Phase I study of ch14.18 with granulocyte-macrophage colony-stimulating factor and interleukin-2 in children with neuroblastoma after autologous bone marrow transplantation or stem-cell rescue: a report from the Children's Oncology Group. J Clin Oncol. 2009 Jan 01; 27(1):85-91. Gilman AL, Ozkaynak MF, Matthay KK, Krailo M, Yu AL, Gan J, Sternberg A, Hank JA, Seeger R, Reaman GH, Sondel PM. PMID: 19047298.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCTClinical Trials
    74. Nonparametric estimation of LOH using Affymetrix SNP genotyping arrays for unpaired samples. J Hum Genet. 2008; 53(11-12):983-990. Huggins R, Li LH, Lin YC, Yu AL, Yang HC. PMID: 18989737.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    75. A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses. Proc Natl Acad Sci U S A. 2008 Sep 09; 105(36):13538-43. Chen MW, Cheng TJ, Huang Y, Jan JT, Ma SH, Yu AL, Wong CH, Ho DD. PMID: 18765801.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    76. Glycan microarray of Globo H and related structures for quantitative analysis of breast cancer. Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33):11661-6. Wang CC, Huang YL, Ren CT, Lin CW, Hung JT, Yu JC, Yu AL, Wu CY, Wong CH. PMID: 18689688.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    77. Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis. Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33):11667-72. Chang WW, Lee CH, Lee P, Lin J, Hsu CW, Hung JT, Lin JJ, Yu JC, Shao LE, Yu J, Wong CH, Yu AL. PMID: 18685093.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    78. c-Myb is an evolutionary conserved miR-150 target and miR-150/c-Myb interaction is important for embryonic development. Mol Biol Evol. 2008 Oct; 25(10):2189-98. Lin YC, Kuo MW, Yu J, Kuo HH, Lin RJ, Lo WL, Yu AL. PMID: 18667440.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    79. MPDA: microarray pooled DNA analyzer. BMC Bioinformatics. 2008 Apr 15; 9:196. Yang HC, Huang MC, Li LH, Lin CH, Yu AL, Diccianni MB, Wu JY, Chen YT, Fann CS. PMID: 18412951.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    80. Charge monitoring cell mass spectrometry. Anal Chem. 2008 Apr 01; 80(7):2524-30. Peng WP, Lin HC, Chu ML, Chang HC, Lin HH, Yu AL, Chen CH. PMID: 18321134.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    81. Human TRIM71 and its nematode homologue are targets of let-7 microRNA and its zebrafish orthologue is essential for development. Mol Biol Evol. 2007 Nov; 24(11):2525-34. Lin YC, Hsieh LC, Kuo MW, Yu J, Kuo HH, Lo WL, Lin RJ, Yu AL, Li WH. PMID: 17890240.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    82. High-speed mass analysis of whole erythrocytes by charge-detection quadrupole ion trap mass spectrometry. Anal Chem. 2007 Oct 01; 79(19):7401-7. Nie Z, Cui F, Tzeng YK, Chang HC, Chu M, Lin HC, Chen CH, Lin HH, Yu AL. PMID: 17784735.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    83. Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids. Proc Natl Acad Sci U S A. 2007 Jun 19; 104(25):10299-304. Chang YJ, Huang JR, Tsai YC, Hung JT, Wu D, Fujio M, Wong CH, Yu AL. PMID: 17566107.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    84. Charge-monitoring laser-induced acoustic desorption mass spectrometry for cell and microparticle mass distribution measurement. Angew Chem Int Ed Engl. 2007; 46(21):3865-9. Peng WP, Lin HC, Lin HH, Chu M, Yu AL, Chang HC, Chen CH. PMID: 17436263.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    85. Synthesis and evaluation of caged Garcinia xanthones. Org Biomol Chem. 2007 Feb 07; 5(3):494-500. Batova A, Lam T, Wascholowski V, Yu AL, Giannis A, Theodorakis EA. PMID: 17252132.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    86. Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor Blimp-1. J Biol Chem. 2006 Aug 25; 281(34):24111-23. Lin KI, Kao YY, Kuo HK, Yang WB, Chou A, Lin HH, Yu AL, Wong CH. PMID: 16798741.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    87. Identification of pulmonary Oct-4+ stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro. Proc Natl Acad Sci U S A. 2006 Jun 20; 103(25):9530-5. Ling TY, Kuo MD, Li CL, Yu AL, Huang YH, Wu TJ, Lin YC, Chen SH, Yu J. PMID: 16772384.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    88. EFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine. Blood. 2006 Feb 01; 107(3):898-903. Batova A, Cottam H, Yu J, Diccianni MB, Carrera CJ, Yu AL. PMID: 16234352.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    89. Temozolomide and radiation for aggressive pediatric central nervous system malignancies. J Pediatr Hematol Oncol. 2005 May; 27(5):254-8. Loh KC, Willert J, Meltzer H, Roberts W, Kerlin B, Kadota R, Levy M, White G, Geddis A, Schiff D, Martin L, Yu A, Kung F, Spear MA. PMID: 15891559.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    90. Expression profiles and clinical relationships of ID2, CDKN1B, and CDKN2A in primary neuroblastoma. Genes Chromosomes Cancer. 2004 Dec; 41(4):297-308. Gebauer S, Yu AL, Omura-Minamisawa M, Batova A, Diccianni MB. PMID: 15390183.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    91. 3-amino thioacridone inhibits DNA synthesis and induce DNA damage in T-cell acute lymphoblastic leukemia (T-ALL) in a p16-dependent manner. J Exp Ther Oncol. 2004 Oct; 4(3):223-37. Diccianni MB, Yu J, Meppelink G, de Vries M, Shao L, Gebauer S, Shih H, Roberts W, Kilcoin NP, Pullen J, Carson DA, Yu AL. PMID: 15724842.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    92. The role of methionine in ethylmalonic encephalopathy with petechiae. Arch Neurol. 2004 Apr; 61(4):570-4. McGowan KA, Nyhan WL, Barshop BA, Naviaux RK, Yu A, Haas RH, Townsend JJ. PMID: 15096407.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    93. Testing of new agents in childhood cancer preclinical models: meeting summary. Clin Cancer Res. 2002 Dec; 8(12):3646-57. Houghton PJ, Adamson PC, Blaney S, Fine HA, Gorlick R, Haber M, Helman L, Hirschfeld S, Hollingshead MG, Israel MA, Lock RB, Maris JM, Merlino G, Patterson W, Reynolds CP, Shannon K, Yu A, Yu J, Smith MA. PMID: 12473573.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    94. The histone deacetylase inhibitor AN-9 has selective toxicity to acute leukemia and drug-resistant primary leukemia and cancer cell lines. Blood. 2002 Nov 01; 100(9):3319-24. Batova A, Shao LE, Diccianni MB, Yu AL, Tanaka T, Rephaeli A, Nudelman A, Yu J. PMID: 12384433.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    95. Treatment of high-risk neuroblastoma with triple-tandem high-dose therapy and stem-cell rescue: results of the Chicago Pilot II Study. J Clin Oncol. 2002 May 01; 20(9):2284-92. Kletzel M, Katzenstein HM, Haut PR, Yu AL, Morgan E, Reynolds M, Geissler G, Marymount MH, Liu D, Kalapurakal JA, Shore RM, Bardo DM, Schmoldt J, Rademaker AW, Cohn SL. PMID: 11980999.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCTClinical Trials
    96. Inhibition of Bcl-xL expression sensitizes T-cell acute lymphoblastic leukemia cells to chemotherapeutic drugs. Leuk Res. 2002 Mar; 26(3):311-6. Broome HE, Yu AL, Diccianni M, Camitta BM, Monia BP, Dean NM. PMID: 11792421.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
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