Igor Wierzbicki

Title(s)Postdoctoral Scholar, Pharmacology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Immunization but not natural infection of horses results in antibody activity against the S protein of Streptococcus equi subsp equi. Am J Vet Res. 2024 Dec 16; 1-11. Cohen ND, Hughes EV, Bayne C, Morris ERA, Bray JM, Landrock KK, Gonzales DM, Baker RM, Klein RL, Liu W, Legere RM, Wehmeyer SG, Bordin AI, Wierzbicki IH, Gonzalez DJ. PMID: 39681079.
      View in: PubMed   Mentions:    Fields:    
    2. Pathobiont-driven antibody sialylation through IL-10 undermines vaccination. J Clin Invest. 2024 Dec 16; 134(24). Tsai CM, Hajam IA, Caldera JR, Chiang AW, Gonzalez C, Du X, Choudhruy B, Li H, Suzuki E, Askarian F, Clark T, Lin B, Wierzbicki IH, Riestra AM, Conrad DJ, Gonzalez DJ, Nizet V, Lewis NE, Liu GY. PMID: 39680460.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
    3. Giant polyketide synthase enzymes in the biosynthesis of giant marine polyether toxins. Science. 2024 08 09; 385(6709):671-678. Fallon TR, Shende VV, Wierzbicki IH, Pendleton AL, Watervoort NF, Auber RP, Gonzalez DJ, Wisecaver JH, Moore BS. PMID: 39116217; PMCID: PMC11416037.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling. J Biol Chem. 2024 Jun; 300(6):107393. Zhuang C, Yang S, Gonzalez CG, Ainsworth RI, Li S, Kobayashi MT, Wierzbicki I, Rossitto LM, Wen Y, Peti W, Stanford SM, Gonzalez DJ, Murali R, Santelli E, Bottini N. PMID: 38777143; PMCID: PMC11237943.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Giant polyketide synthase enzymes biosynthesize a giant marine polyether biotoxin. bioRxiv. 2024 Jan 31. Fallon TR, Shende VV, Wierzbicki IH, Auber RP, Gonzalez DJ, Wisecaver JH, Moore BS. PMID: 38352448; PMCID: PMC10862718.
      View in: PubMed   Mentions:
    6. Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness. Cell Metab. 2023 06 06; 35(6):1009-1021.e9. Gu L, Zhu Y, Watari K, Lee M, Liu J, Perez S, Thai M, Mayfield JE, Zhang B, Cunha E Rocha K, Li F, Kim LC, Jones AC, Wierzbicki IH, Liu X, Newton AC, Kisseleva T, Lee JH, Ying W, Gonzalez DJ, Saltiel AR, Simon MC, Karin M. PMID: 37084733; PMCID: PMC10430883.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    7. Group A Streptococcal S Protein Utilizes Red Blood Cells as Immune Camouflage and Is a Critical Determinant for Immune Evasion. Cell Rep. 2019 12 03; 29(10):2979-2989.e15. Wierzbicki IH, Campeau A, Dehaini D, Holay M, Wei X, Greene T, Ying M, Sands JS, Lamsa A, Zuniga E, Pogliano K, Fang RH, LaRock CN, Zhang L, Gonzalez DJ. PMID: 31801066; PMCID: PMC6951797.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    8. Structural and functional insights into the role of BamD and BamE within the β-barrel assembly machinery in Neisseria gonorrhoeae. J Biol Chem. 2018 01 26; 293(4):1106-1119. Sikora AE, Wierzbicki IH, Zielke RA, Ryner RF, Korotkov KV, Buchanan SK, Noinaj N. PMID: 29229778; PMCID: PMC5787791.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    9. Functional and structural studies on the Neisseria gonorrhoeae GmhA, the first enzyme in the glycero-manno-heptose biosynthesis pathways, demonstrate a critical role in lipooligosaccharide synthesis and gonococcal viability. Microbiologyopen. 2017 04; 6(2). Wierzbicki IH, Zielke RA, Korotkov KV, Sikora AE. PMID: 28063198; PMCID: PMC5387315.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    10. Proteomics-driven Antigen Discovery for Development of Vaccines Against Gonorrhea. Mol Cell Proteomics. 2016 07; 15(7):2338-55. Zielke RA, Wierzbicki IH, Baarda BI, Gafken PR, Soge OO, Holmes KK, Jerse AE, Unemo M, Sikora AE. PMID: 27141096; PMCID: PMC4937508.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    11. Polymeric Micelles as Carriers for Nerve-Highlighting Fluorescent Probe Delivery. Mol Pharm. 2015 Dec 07; 12(12):4386-94. Hackman KM, Doddapaneni BS, Barth CW, Wierzbicki IH, Alani AW, Gibbs SL. PMID: 26485440; PMCID: PMC4674818.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    12. The Neisseria gonorrhoeae Obg protein is an essential ribosome-associated GTPase and a potential drug target. BMC Microbiol. 2015 Jun 30; 15:129. Zielke RA, Wierzbicki IH, Baarda BI, Sikora AE. PMID: 26122105; PMCID: PMC4487204.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    13. A metalloprotease secreted by the type II secretion system links Vibrio cholerae with collagen. J Bacteriol. 2015 Mar; 197(6):1051-64. Park BR, Zielke RA, Wierzbicki IH, Mitchell KC, Withey JH, Sikora AE. PMID: 25561716; PMCID: PMC4336349.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    14. In situ gelling polyvalerolactone-based thermosensitive hydrogel for sustained drug delivery. Eur J Pharm Biopharm. 2014 Oct; 88(2):397-405. Mishra GP, Kinser R, Wierzbicki IH, Alany RG, Alani AW. PMID: 24931340.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    15. Quantitative proteomics of the Neisseria gonorrhoeae cell envelope and membrane vesicles for the discovery of potential therapeutic targets. Mol Cell Proteomics. 2014 May; 13(5):1299-317. Zielke RA, Wierzbicki IH, Weber JV, Gafken PR, Sikora AE. PMID: 24607996; PMCID: PMC4014286.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
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