Samuel Rapaport

Title(s)Emeritus Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    NIH U09RG010773Oct 1, 1985 - Jun 30, 1991
    Role: Co-Principal Investigator
    NIH R37HL027234May 1, 1981 - Apr 30, 1997
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The multiple faces of the partial thromboplastin time APTT. J Thromb Haemost. 2004 Dec; 2(12):2250-9. Rapaport SI, Vermylen J, Hoylaerts M, Saito H, Hirsh J, Bates S, Dahlbäck B, Poller L. PMID: 15613038.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    2. Coagulation problems in liver disease. Blood Coagul Fibrinolysis. 2000 Apr; 11 Suppl 1:S69-74. Rapaport SI. PMID: 10850568.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    3. A novel clotting assay for quantitation of plasma prothrombin (factor II) using Echis multisquamatus venom. Am J Clin Pathol. 1999 Nov; 112(5):705-11. Petrovan RJ, Rapaport SI, Le DT. PMID: 10549258.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. Hemostatic factors in rabbit limb lymph: relationship to mechanisms regulating extravascular coagulation. Am J Physiol. 1998 03; 274(3):H769-76. Le DT, Borgs P, Toneff TW, Witte MH, Rapaport SI. PMID: 9530187.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    5. A Protac-based screening test for activated protein C-resistant factor Va and other defects of the protein C anticoagulant pathway. Blood Coagul Fibrinolysis. 1997 Sep; 8(6):327-35. Gable PS, Le DT, McGehee W, Rapaport SI. PMID: 9351522.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Presentation of the 1997 George M. Kober Medal to Helen Ranney. Proc Assoc Am Physicians. 1997 Sep; 109(5):494-503. Rapaport SI. PMID: 9285948.
      View in: PubMed   Mentions:    Fields:    
    7. Correction of excessive anticoagulation with low-dose oral vitamin K1. Ann Intern Med. 1997 Jun 15; 126(12):959-62. Weibert RT, Le DT, Kayser SR, Rapaport SI. PMID: 9182473.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    8. Protac, a commercially available protein C activator from the venom of Agkistrodon contortrix contortrix, can activate factor V and factor VIII. Thromb Res. 1997 Apr 01; 86(1):79-84. Gable PS, Le DT, Rapaport SI. PMID: 9172290.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. Reliability of a modified tissue factor-dependent factor V assay for activated protein C resistant factor Va using a calcium-containing thromboplastin. Thromb Haemost. 1997 Mar; 77(3):481-5. Le DT, Donnelly KJ, Wu N, Sevilla BK, Rapaport SI. PMID: 9065998.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. The effect of immunodepletion of antithrombin III on the response of rabbits to Russell's viper venom-induced activation of factor X. Arterioscler Thromb Vasc Biol. 1997 Feb; 17(2):409-16. Rapaport SI, Toneff T, Rimon A, Warn-Cramer BJ. PMID: 9081698.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    11. Plasma PIVKA proteins in rabbits given warfarin. Thromb Res. 1996 Jun 01; 82(5):429-38. Zivelin A, Rao LV, Rapaport SI. PMID: 8771703.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    12. The tissue factor pathway: how it has become a "prima ballerina". Thromb Haemost. 1995 Jul; 74(1):7-17. Rapaport SI, Rao LV. PMID: 8578528.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    13. Use of a generally applicable tissue factor--dependent factor V assay to detect activated protein C-resistant factor Va in patients receiving warfarin and in patients with a lupus anticoagulant. Blood. 1995 Apr 01; 85(7):1704-11. Le DT, Griffin JH, Greengard JS, Mujumdar V, Rapaport SI. PMID: 7703480.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. Evidence for an essential role of tissue factor dependent blood coagulation in the pathogenesis of the local Shwartzman reaction. Blood Cells Mol Dis. 1995; 21(1):9-19. Zivelin A, Rao LV, Rapaport SI. PMID: 7655863.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    15. Evidence suggestive of activation of the intrinsic pathway of blood coagulation after injection of factor Xa/phospholipid into rabbits. Arterioscler Thromb Vasc Biol. 1995 Jan; 15(1):133-9. Warn-Cramer BJ, Rapaport SI. PMID: 7749809.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    16. Studies of the mechanism for enhanced cell surface factor VIIa/tissue factor activation of factor X on fibroblast monolayers after their exposure to N-ethylmaleimide. Thromb Haemost. 1994 Dec; 72(6):848-55. Le DT, Rapaport SI, Rao LV. PMID: 7740453.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    17. Functional and binding studies of the roles of prothrombin and beta 2-glycoprotein I in the expression of lupus anticoagulant activity. Blood. 1994 May 15; 83(10):2878-92. Permpikul P, Rao LV, Rapaport SI. PMID: 8180383.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    18. The international normalized ratio (INR) for monitoring warfarin therapy: reliability and relation to other monitoring methods. Ann Intern Med. 1994 Apr 01; 120(7):552-8. Le DT, Weibert RT, Sevilla BK, Donnelly KJ, Rapaport SI. PMID: 8116992.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    19. Studies of factor Xa/phospholipid-induced intravascular coagulation in rabbits. Effects of immunodepletion of tissue factor pathway inhibitor. Arterioscler Thromb. 1993 Nov; 13(11):1551-7. Warn-Cramer BJ, Rapaport SI. PMID: 8218094.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    20. Mechanism of the anticoagulant effect of warfarin as evaluated in rabbits by selective depression of individual procoagulant vitamin K-dependent clotting factors. J Clin Invest. 1993 Nov; 92(5):2131-40. Zivelin A, Rao LV, Rapaport SI. PMID: 8227329; PMCID: PMC288391.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    21. Binding of factor VIIa to tissue factor permits rapid antithrombin III/heparin inhibition of factor VIIa. Blood. 1993 May 15; 81(10):2600-7. Rao LV, Rapaport SI, Hoang AD. PMID: 8490170.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    22. Trousseau's syndrome. West J Med. 1993 Apr; 158(4):364-71. Callander N, Rapaport SI. PMID: 8317122; PMCID: PMC1022062.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    23. Heparin-releasable and platelet pools of tissue factor pathway inhibitor in rabbits. Thromb Haemost. 1993 Mar 01; 69(3):221-6. Warn-Cramer BJ, Maki SL, Rapaport SI. PMID: 8470044.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    24. Blood coagulation and its alterations in hemorrhagic and thrombotic disorders. West J Med. 1993 Feb; 158(2):153-61. Rapaport SI. PMID: 8434467; PMCID: PMC1021969.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Regulation of factor VIIa/tissue factor functional activity in an umbilical vein model. Arterioscler Thromb. 1993 Jan; 13(1):105-11. Almus FE, Rao LV, Rapaport SI. PMID: 8422331.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Initiation and regulation of tissue factor-dependent blood coagulation. Arterioscler Thromb. 1992 Oct; 12(10):1111-21. Rapaport SI, Rao LV. PMID: 1390583.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    27. Relations between factor VIIa binding and expression of factor VIIa/tissue factor catalytic activity on cell surfaces. J Biol Chem. 1992 Aug 05; 267(22):15447-54. Le DT, Rapaport SI, Rao LV. PMID: 1639786.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    28. Mechanisms of binding of recombinant extrinsic pathway inhibitor (rEPI) to cultured cell surfaces. Evidence that rEPI can bind to and inhibit factor VIIa-tissue factor complexes in the absence of factor Xa. J Biol Chem. 1992 Jan 15; 267(2):876-82. Callander NS, Rao LV, Nordfang O, Sandset PM, Warn-Cramer B, Rapaport SI. PMID: 1730676.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    29. Clinical significance of antibodies to bovine and human thrombin and factor V after surgical use of bovine thrombin. Am J Clin Pathol. 1992 Jan; 97(1):84-91. Rapaport SI, Zivelin A, Minow RA, Hunter CS, Donnelly K. PMID: 1728869.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    30. Immunodepletion of extrinsic pathway inhibitor sensitizes rabbits to endotoxin-induced intravascular coagulation and the generalized Shwartzman reaction. Blood. 1991 Sep 15; 78(6):1496-502. Sandset PM, Warn-Cramer BJ, Maki SL, Rapaport SI. PMID: 1909195.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    31. Mechanism for diminished tissue factor expression by endothelial cells cultured with heparin binding growth factor-1 and heparin. Blood. 1991 Mar 15; 77(6):1256-62. Almus FE, Rao LV, Pendurthi UR, Quattrochi L, Rapaport SI. PMID: 1705837.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    32. A sulfated rabbit endothelial cell glycoprotein that inhibits factor VIIa/tissue factor is functionally and immunologically identical to rabbit extrinsic pathway inhibitor (EPI). Thromb Res. 1991 Mar; 61(5-6):515-27. Warn-Cramer BJ, Maki SL, Rapaport SI. PMID: 2028453.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    33. Depletion of extrinsic pathway inhibitor (EPI) sensitizes rabbits to disseminated intravascular coagulation induced with tissue factor: evidence supporting a physiologic role for EPI as a natural anticoagulant. Proc Natl Acad Sci U S A. 1991 Feb 01; 88(3):708-12. Sandset PM, Warn-Cramer BJ, Rao LV, Maki SL, Rapaport SI. PMID: 1899482; PMCID: PMC50882.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    34. Regulation of the tissue factor pathway. Ann N Y Acad Sci. 1991; 614:51-62. Rapaport SI. PMID: 2024893.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    35. A sensitive, accurate assay for extrinsic pathway inhibitor (EPI) activity in rabbit plasma: paradoxical effect of excess exogenous factor X. Thromb Res. 1990 Aug 15; 59(4):773-82. Warr TA, Rao LV, Rapaport SI. PMID: 2080494.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    36. Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody. Thromb Res. 1990 Jul 15; 59(2):421-37. Fleck RA, Rao LV, Rapaport SI, Varki N. PMID: 2237820.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCells
    37. Properties of factor VIIa/tissue factor complexes in an umbilical vein model. Blood. 1990 Jul 15; 76(2):354-60. Almus FE, Rao LV, Fleck RA, Rapaport SI. PMID: 2114934.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    38. Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway inhibitor activity. Blood. 1990 Apr 01; 75(7):1481-9. Warr TA, Rao LV, Rapaport SI. PMID: 2317559.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    39. Factor VIIa-catalyzed activation of factor X independent of tissue factor: its possible significance for control of hemophilic bleeding by infused factor VIIa. Blood. 1990 Mar 01; 75(5):1069-73. Rao LV, Rapaport SI. PMID: 2306514.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    40. Assessing hemostatic function before abdominal interventions. AJR Am J Roentgenol. 1990 Feb; 154(2):239-40. Rapaport SI. PMID: 2105006.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    41. The initiation of the tissue factor dependent pathway of blood coagulation. Adv Exp Med Biol. 1990; 281:97-103. Rapaport SI. PMID: 2102629.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    42. Functional properties of factor VIIa/tissue factor formed with purified tissue factor and with tissue factor expressed on cultured endothelial cells. Thromb Haemost. 1989 Dec 29; 62(4):1067-73. Almus FE, Rao LV, Rapaport SI. PMID: 2617454.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    43. Human plasma extrinsic pathway inhibitor activity: II. Plasma levels in disseminated intravascular coagulation and hepatocellular disease. Blood. 1989 Aug 15; 74(3):994-8. Warr TA, Rao LV, Rapaport SI. PMID: 2787683.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    44. Human plasma extrinsic pathway inhibitor activity: I. Standardization of assay and evaluation of physiologic variables. Blood. 1989 Jul; 74(1):201-6. Warr TA, Warn-Cramer BJ, Rao LV, Rapaport SI. PMID: 2473796.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Studies of the factor Xa-dependent inhibitor of factor VIIa/tissue factor (extrinsic pathway inhibitor) from cell supernates of cultured human umbilical vein endothelial cells. Thromb Haemost. 1989 Feb 28; 61(1):101-5. Warn-Cramer BJ, Almus FE, Rapaport SI. PMID: 2665164.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    46. Inhibition of factor VIIa/tissue factor-induced blood coagulation: with particular emphasis upon a factor Xa-dependent inhibitory mechanism. Blood. 1989 Feb; 73(2):359-65. Rapaport SI. PMID: 2644974.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    47. Modifications of extrinsic pathway inhibitor (EPI) and factor Xa that affect their ability to interact and to inhibit factor VIIa/tissue factor: evidence for a two-step model of inhibition. Thromb Haemost. 1988 Dec 22; 60(3):453-6. Warn-Cramer BJ, Rao LV, Maki SL, Rapaport SI. PMID: 3238648.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    48. Activation of factor VII bound to tissue factor: a key early step in the tissue factor pathway of blood coagulation. Proc Natl Acad Sci U S A. 1988 Sep; 85(18):6687-91. Rao LV, Rapaport SI. PMID: 3261869; PMCID: PMC282042.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    49. The effect of platelets upon factor Xa-catalyzed activation of factor VII in vitro. Blood. 1988 Aug; 72(2):396-401. Rao LV, Rapaport SI. PMID: 3135857.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    50. Anti-prothrombin antibodies and the lupus anticoagulant. Blood. 1988 Aug; 72(2):512-9. Fleck RA, Rapaport SI, Rao LV. PMID: 2456797.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    51. Decreased inducibility of tissue factor activity on human umbilical vein endothelial cells cultured with endothelial cell growth factor and heparin. Thromb Res. 1988 Apr 15; 50(2):339-44. Almus FE, Rao LV, Rapaport SI. PMID: 3394119.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    52. Enhancement by human umbilical vein endothelial cells of factor Xa-catalyzed activation of factor VII. Blood. 1988 Mar; 71(3):791-6. Rao LV, Rapaport SI, Lorenzi M. PMID: 3422831.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    53. Partial purification and characterization of extrinsic pathway inhibitor (the factor Xa-dependent plasma inhibitor of factor VIIa/tissue factor). Thromb Res. 1987 Oct 01; 48(1):11-22. Warn-Cramer BJ, Maki SL, Zivelin A, Rapaport SI. PMID: 3501173.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    54. Affinity purification of human brain tissue factor utilizing factor VII bound to immobilized anti-factor VII. Anal Biochem. 1987 Sep; 165(2):365-70. Rao LV, Rapaport SI. PMID: 3425896.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
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