Philbert Tsai

Title(s)	Lecturer, Physics
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
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Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Brain Capillary Networks Across Species: A few Simple Organizational Requirements Are Sufficient to Reproduce Both Structure and Function. Front Physiol. 2019; 10:233. Smith AF, Doyeux V, Berg M, Peyrounette M, Haft-Javaherian M, Larue AE, Slater JH, Lauwers F, Blinder P, Tsai P, Kleinfeld D, Schaffer CB, Nishimura N, Davit Y, Lorthois S. PMID: 30971935.

View in: PubMed Mentions:
Entrainment of Arteriole Vasomotor Fluctuations by Neural Activity Is a Basis of Blood-Oxygenation-Level-Dependent "Resting-State" Connectivity. Neuron. 2017 Nov 15; 96(4):936-948.e3. Mateo C, Knutsen PM, Tsai PS, Shih AY, Kleinfeld D. PMID: 29107517.

View in: PubMed Mentions: 63 Fields:
Neu Neurology
Translation:Animals
The impact of vessel size, orientation and intravascular contribution on the neurovascular fingerprint of BOLD bSSFP fMRI. Neuroimage. 2017 12; 163:13-23. Báez-Yánez MG, Ehses P, Mirkes C, Tsai PS, Kleinfeld D, Scheffler K. PMID: 28890417.

View in: PubMed Mentions: 8 Fields:
Dia Diagnostic Imaging
Translation:Animals
Depth-dependent flow and pressure characteristics in cortical microvascular networks. PLoS Comput Biol. 2017 02; 13(2):e1005392. Schmid F, Tsai PS, Kleinfeld D, Jenny P, Weber B. PMID: 28196095.

View in: PubMed Mentions: 26 Fields:
Com Computational Biology
Translation:Animals Cells
Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain. Nat Neurosci. 2017 Mar; 20(3):406-416. Kisler K, Nelson AR, Rege SV, Ramanathan A, Wang Y, Ahuja A, Lazic D, Tsai PS, Zhao Z, Zhou Y, Boas DA, Sakadžic S, Zlokovic BV. PMID: 28135240.

View in: PubMed Mentions: 132 Fields:
Neu Neurology
Translation:Animals Cells
The capillary bed offers the largest hemodynamic resistance to the cortical blood supply. J Cereb Blood Flow Metab. 2017 01; 37(1):52-68. Gould IG, Tsai P, Kleinfeld D, Linninger A. PMID: 27780904.

View in: PubMed Mentions: 55 Fields:
Bra Brain Met Metabolism Vas Vascular Diseases
Translation:Animals
Ultra-large field-of-view two-photon microscopy. Opt Express. 2015 Jun 01; 23(11):13833-47. Tsai PS, Mateo C, Field JJ, Schaffer CB, Anderson ME, Kleinfeld D. PMID: 26072755.

View in: PubMed Mentions: 36 Fields:
Bio Biophysics Oph Ophthalmology
Translation:Animals
Robust and fragile aspects of cortical blood flow in relation to the underlying angioarchitecture. Microcirculation. 2015 Apr; 22(3):204-218. Shih AY, Rühlmann C, Blinder P, Devor A, Drew PJ, Friedman B, Knutsen PM, Lyden PD, Mateo C, Mellander L, Nishimura N, Schaffer CB, Tsai PS, Kleinfeld D. PMID: 25705966.

View in: PubMed Mentions: 35 Fields:
Vas Vascular Diseases
Translation:Humans Animals Cells
All-optical osteotomy to create windows for transcranial imaging in mice. Opt Express. 2013 Oct 07; 21(20):23160-8. Jeong DC, Tsai PS, Kleinfeld D. PMID: 24104230.

View in: PubMed Mentions: 8 Fields:
Bio Biophysics Oph Ophthalmology
Translation:Animals
The cortical angiome: an interconnected vascular network with noncolumnar patterns of blood flow. Nat Neurosci. 2013 Jul; 16(7):889-97. Blinder P, Tsai PS, Kaufhold JP, Knutsen PM, Suhl H, Kleinfeld D. PMID: 23749145.

View in: PubMed Mentions: 183 Fields:
Neu Neurology
Translation:Animals Cells
All-optical in situ histology of brain tissue with femtosecond laser pulses. Cold Spring Harb Protoc. 2013 Apr 01; 2013(4):327-34. Tsai PS, Blinder P, Squier JA, Kleinfeld D. PMID: 23547156.

View in: PubMed Mentions: Fields:
Cli Clinical Laboratory Techniques
Translation:Animals
The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit. Nat Neurosci. 2013 Jan; 16(1):55-63. Shih AY, Blinder P, Tsai PS, Friedman B, Stanley G, Lyden PD, Kleinfeld D. PMID: 23242312.

View in: PubMed Mentions: 118 Fields:
Neu Neurology
Translation:Humans Animals
Vectorization of optically sectioned brain microvasculature: learning aids completion of vascular graphs by connecting gaps and deleting open-ended segments. Med Image Anal. 2012 Aug; 16(6):1241-58. Kaufhold JP, Tsai PS, Blinder P, Kleinfeld D. PMID: 22854035.

View in: PubMed Mentions: 11 Fields:
Dia Diagnostic Imaging
Translation:Humans Animals
A polished and reinforced thinned-skull window for long-term imaging of the mouse brain. J Vis Exp. 2012 Mar 07; (61). Shih AY, Mateo C, Drew PJ, Tsai PS, Kleinfeld D. PMID: 22433225.

View in: PubMed Mentions: 57 Fields:
Bio Biology Med Medicine (General)
Translation:Animals
Prospect for feedback guided surgery with ultra-short pulsed laser light. Curr Opin Neurobiol. 2012 Feb; 22(1):24-33. Jeong DC, Tsai PS, Kleinfeld D. PMID: 22088392.

View in: PubMed Mentions: 11 Fields:
Bio Biology Neu Neurology
Translation:Humans Animals
Large-scale automated histology in the pursuit of connectomes. J Neurosci. 2011 Nov 09; 31(45):16125-38. Kleinfeld D, Bharioke A, Blinder P, Bock DD, Briggman KL, Chklovskii DB, Denk W, Helmstaedter M, Kaufhold JP, Lee WC, Meyer HS, Micheva KD, Oberlaender M, Prohaska S, Reid RC, Smith SJ, Takemura S, Tsai PS, Sakmann B. PMID: 22072665.

View in: PubMed Mentions: 71 Fields:
Neu Neurology
Translation:Humans Animals Cells
A guide to delineate the logic of neurovascular signaling in the brain. Front Neuroenergetics. 2011; 3:1. Kleinfeld D, Blinder P, Drew PJ, Driscoll JD, Muller A, Tsai PS, Shih AY. PMID: 21559095.

View in: PubMed Mentions:
Chronic optical access through a polished and reinforced thinned skull. Nat Methods. 2010 Dec; 7(12):981-4. Drew PJ, Shih AY, Driscoll JD, Knutsen PM, Blinder P, Davalos D, Akassoglou K, Tsai PS, Kleinfeld D. PMID: 20966916.

View in: PubMed Mentions: 178 Fields:
Cli Clinical Laboratory Techniques
Translation:Animals
Temporally focused femtosecond laser pulses for low numerical aperture micromachining through optically transparent materials. Opt Express. 2010 Aug 16; 18(17):18086-94. Vitek DN, Adams DE, Johnson A, Tsai PS, Backus S, Durfee CG, Kleinfeld D, Squier JA. PMID: 20721196.

View in: PubMed Mentions: 12 Fields:
Bio Biophysics Oph Ophthalmology
Translation:Animals
Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels. J Neurosci. 2009 Nov 18; 29(46):14553-70. Tsai PS, Kaufhold JP, Blinder P, Friedman B, Drew PJ, Karten HJ, Lyden PD, Kleinfeld D. PMID: 19923289.

View in: PubMed Mentions: 210 Fields:
Neu Neurology
Translation:Animals Cells
Severe blood-brain barrier disruption and surrounding tissue injury. Stroke. 2009 Dec; 40(12):e666-74. Chen B, Friedman B, Cheng Q, Tsai P, Schim E, Kleinfeld D, Lyden PD. PMID: 19893002.

View in: PubMed Mentions: 54 Fields:
Bra Brain Vas Vascular Diseases
Translation:Animals
Acute vascular disruption and aquaporin 4 loss after stroke. Stroke. 2009 Jun; 40(6):2182-90. Friedman B, Schachtrup C, Tsai PS, Shih AY, Akassoglou K, Kleinfeld D, Lyden PD. PMID: 19372455.

View in: PubMed Mentions: 29 Fields:
Bra Brain Vas Vascular Diseases
Translation:Animals Cells
Plasma-mediated ablation: an optical tool for submicrometer surgery on neuronal and vascular systems. Curr Opin Biotechnol. 2009 Feb; 20(1):90-9. Tsai PS, Blinder P, Migliori BJ, Neev J, Jin Y, Squier JA, Kleinfeld D. PMID: 19269159.

View in: PubMed Mentions: 24 Fields:
Bio Biotechnology
Translation:Humans Animals
Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke. J Cereb Blood Flow Metab. 2009 Apr; 29(4):738-51. Shih AY, Friedman B, Drew PJ, Tsai PS, Lyden PD, Kleinfeld D. PMID: 19174826.

View in: PubMed Mentions: 49 Fields:
Bra Brain Met Metabolism Vas Vascular Diseases
Translation:Animals Cells
MPScope: a versatile software suite for multiphoton microscopy. J Neurosci Methods. 2006 Sep 30; 156(1-2):351-9. Nguyen QT, Tsai PS, Kleinfeld D. PMID: 16621010.

View in: PubMed Mentions: 52 Fields:
Neu Neurology
Translation:Animals
Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke. Nat Methods. 2006 Feb; 3(2):99-108. Nishimura N, Schaffer CB, Friedman B, Tsai PS, Lyden PD, Kleinfeld D. PMID: 16432519.

View in: PubMed Mentions: 119 Fields:
Cli Clinical Laboratory Techniques
Translation:Animals Cells
Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion. PLoS Biol. 2006 Feb; 4(2):e22. Schaffer CB, Friedman B, Nishimura N, Schroeder LF, Tsai PS, Ebner FF, Lyden PD, Kleinfeld D. PMID: 16379497.

View in: PubMed Mentions: 149 Fields:
Bio Biology
Translation:Animals
All-optical histology using ultrashort laser pulses. Neuron. 2003 Jul 03; 39(1):27-41. Tsai PS, Friedman B, Ifarraguerri AI, Thompson BD, Lev-Ram V, Schaffer CB, Xiong Q, Tsien RY, Squier JA, Kleinfeld D. PMID: 12848930.

View in: PubMed Mentions: 61 Fields:
Neu Neurology
Translation:Animals Cells