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    Jeffrey Harris

    Address200 W. Arbor Drive #8895
    CA San Diego 92103
    Phone619-543-7895
    vCardDownload vCard

      Collapse Overview 
      Collapse Overview
      Dr. Jeffrey Harris is Chief of the Division of Otolaryngology-Head & Neck Surgery at the University of California, San Diego. A neuro-otologic surgeon who deals with disorders of the ear, hearing and balance, and tumors which affect the skull base, he obtained both his MD and PhD at the University of Pennsylvania and performed his otolaryngology residency training at Harvard. He did advanced fellowship training in Neurotology and Skull Base Surgery at the University of Zurich, and holds two board certifications in both otolaryngology and neurotology/skull base surgery.

      Dr. Harris has an active clinical practice and leads a large research team committed to discovering the causes of deafness and other disorders such as acoustic neuromas, Meniere's disease, and autoimmune inner ear disease.

      Dr. Harris has been named one of the outstanding Otolaryngologists in Town and Country Magazine, American Health Magazine, San Diego Magazine, and Best Doctors in America by Woodward and White. The UCSD Division of Otolaryngology has been listed as one of the best Otolaryngology programs in the country by U.S. News & World Report.

      Dr. Harris became a faculty member of the UCSD Division of Otolaryngology-Head & Neck Surgery in 1979. He was appointed Chief of the division in 1986, and obtained a full Professorship in 1989.

      He has served on several scientific review boards including the NIH, the Deafness Research Foundation, the American Otologic Society, the House Ear Institute, and the American Academy of Otolaryngology/Head & Neck Surgery. He co-chaired the Expert Panel on Hearing and Hearing Impairment for the NIH, which identified the priorities for federal funding of hearing research over the next decade. He is a past President of the Association for Research in Otolaryngology, the largest international organization devoted to research in Otolaryngology, and a past President of the San Diego Academy of Otolaryngology, and has recently served as President of the American Otological Society. He has also served as Chief of Staff for both the Medical Center and the Thornton Hospital, and on the Board of Governors for the UCSD Medical Group.

      Dr. Harris has been a Visiting Professor at many prestigious universities and institutions, including Harvard, Johns Hopkins, Michigan, Iowa, Pennsylvania, Washington, the Mayo Clinic, Stanford, University of Chicago, Baylor, British Columbia, University of Paris, University of Zurich, Utrecht, Toronto, and the Cleveland Clinic. He has been an invited guest speaker at the Academies of Otolaryngology in Britain, Ireland, Canada, Mexico, Norway, China, Spain, Brazil, Korea, and Thailand. He is on the editorial board of many scientific journals, is Editor in Chief of Audiology and Neurotology, and has published three books and over 200 scientific articles.

      Dr. Harris has been recommended repeatedly as one of the top otolaryngologists in the city by San Diego Magazine.

      Research Overview
      I have had a career long interest in the effects of inflammation and immunity on the sensory system of the inner ear. This has led to the quest for diagnostic tests for the different causes of rapid hearing loss and treatment strategies to reverse hearing losses. As a surgeon, I am also Interested in developing innovative surgical tools in collaboration with bioengineering for microsurgery of the ear.

      Research Topics
      - Clinical Trials
      - Drug Delivery
      - Inflammation
      - Injury
      - Outcomes
      - Translational Research

      Current Project Titles
      Clinical trials in autoimmune deafness, Meniere's disease and sudden hearing loss. Interested in antibody mediated deafness including rheumatic disorders involving the G-I tract and paraneoplastic syndromes. Outcome studies in Gamma Knife and other forms of stereotactic radiosurgery for Acoustic Neuromas.


      Collapse Research 
      Collapse Research Activities and Funding
      RESEARCH TRAINING CENTER IN OTOLARYNGOLOGY
      NIH/NIDCD P20DC001433Sep 30, 1991 - Aug 31, 1993
      Role: Principal Investigator
      THIRD NATIONAL CONFERENCE ON RESEARCH GOALS AND METHODS
      NIH/NIDCD R13DC001232Mar 11, 1991 - Mar 31, 1991
      Role: Principal Investigator
      THIRD INTERNATIONAL CONFERENCE ON IMMUNOLOGY IN ENT
      NIH/NIDCD R13DC000851Jul 1, 1990 - Jun 30, 1991
      Role: Principal Investigator
      EXPERIMENTAL CYTOMEGALOVIRAL LABYRINTHITIS
      NIH/NINDS R01NS021485Dec 1, 1984 - Jun 30, 1988
      Role: Principal Investigator
      ASPECTS OF INNER EAR IMMUNOLOGY
      NIH/NIDCD R01DC000193Jul 1, 1982 - Jul 31, 1999
      Role: Principal Investigator
      ASPECTS OF INNER EAR IMMUNOLOGY
      NIH/NINDS R01NS018643Jul 1, 1982 - Nov 30, 1988
      Role: Principal Investigator
      ASPECTS OF INNER EAR IMMUNOLOGY
      NIH/NINDS K07NS000606Jul 1, 1981 - Jun 30, 1986
      Role: Principal Investigator

      Collapse ORNG Applications 
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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Hobson CE, Alexander TH, Harris J. Primary treatment of idiopathic sudden sensorineural hearing loss with intratympanic dexamethasone. Curr Opin Otolaryngol Head Neck Surg. 2016 Oct; 24(5):407-12. PMID: 27379547.
        View in: PubMed
      2. Harris J, Wong YT, Yang TH, Miller M. How I do it: Anterior pull-through tympanoplasty for anterior eardrum perforations. Acta Otolaryngol. 2016 Apr; 136(4):414-9. PMID: 26988908.
        View in: PubMed
      3. Alexander TH, Harris J, Nguyen QT, Vorasubin N. Dose Effect of Intratympanic Dexamethasone for Idiopathic Sudden Sensorineural Hearing Loss: 24 mg/mL Is Superior to 10 mg/mL. Otol Neurotol. 2015 Sep; 36(8):1321-7. PMID: 26196209.
        View in: PubMed
      4. Greene JJ, Keefe MW, Harris J, Matsuoka AJ. Paraneoplastic syndrome: a masquerade of autoimmune inner ear disease. Otol Neurotol. 2015 Jan; 36(1):e3-e10. PMID: 25427223.
        View in: PubMed
      5. Alexander TH, Harris J. Incidence of sudden sensorineural hearing loss. Otol Neurotol. 2013 Dec; 34(9):1586-9. PMID: 24232060.
        View in: PubMed
      6. Matsuoka AJ, Harris J. Autoimmune inner ear disease: a retrospective review of forty-seven patients. Audiol Neurootol. 2013; 18(4):228-39. PMID: 23817208.
        View in: PubMed
      7. Halpin C, Shi H, Reda D, Antonelli PJ, Babu S, Carey JP, Gantz BJ, Goebel JA, Hammerschlag PE, Harris J, Isaacson B, Lee D, Linstrom CJ, Parnes LS, Slattery WH, Telian SA, Vrabec JT, Rauch S. Audiology in the sudden hearing loss clinical trial. Otol Neurotol. 2012 Aug; 33(6):907-11. PMID: 22805100.
        View in: PubMed
      8. Rauch SD, Halpin CF, Antonelli PJ, Babu S, Carey JP, Gantz BJ, Goebel JA, Hammerschlag PE, Harris J, Isaacson B, Lee D, Linstrom CJ, Parnes LS, Shi H, Slattery WH, Telian SA, Vrabec JT, Reda DJ. Oral vs intratympanic corticosteroid therapy for idiopathic sudden sensorineural hearing loss: a randomized trial. JAMA. 2011 May 25; 305(20):2071-9. PMID: 21610239.
        View in: PubMed
      9. Baik FM, Nguyen L, Doherty JK, Harris J, Mafee MF, Nguyen QT. Comparative case series of exostoses and osteomas of the internal auditory canal. Ann Otol Rhinol Laryngol. 2011 Apr; 120(4):255-60. PMID: 21585156.
        View in: PubMed
      10. Altuna X, Lopez JP, Yu MA, Arandazi MJ, Harris J, Wang-Rodriguez J, An Y, Dobrow R, Doherty JK, Ongkeko WM. Potential role of imatinib mesylate (Gleevec, STI-571) in the treatment of vestibular schwannoma. Otol Neurotol. 2011 Jan; 32(1):163-70. PMID: 21157293.
        View in: PubMed
      11. Nguyen LT, Harris J, Nguyen QT. Erosive external otitis: a novel distinct clinical entity of the external auditory canal in nonimmunosuppressed individuals. Otol Neurotol. 2010 Dec; 31(9):1409-11. PMID: 21113981.
        View in: PubMed
      12. Alexander TH, Harris J. Current epidemiology of Meniere's syndrome. Otolaryngol Clin North Am. 2010 Oct; 43(5):965-70. PMID: 20713236.
        View in: PubMed
      13. Nguyen LT, Harris J, Nguyen QT. Clinical utility of electrocochleography in the diagnosis and management of Ménière's disease: AOS and ANS membership survey data. Otol Neurotol. 2010 Apr; 31(3):455-9. PMID: 20104195.
        View in: PubMed
      14. Harris J, Alexander TH. Current-day prevalence of Ménière's syndrome. Audiol Neurootol. 2010; 15(5):318-22. PMID: 20173319.
        View in: PubMed
      15. King JF, Kinney AC, Iacobellis SF, Alexander TH, Harris J, Torre P, Doherty JK, Nguyen QT. Laterality of exostosis in surfers due to evaporative cooling effect. Otol Neurotol. 2010 Feb; 31(2):345-51. PMID: 19806064.
        View in: PubMed
      16. Nguyen LT, Baik FM, Doherty JK, Harris J, Nguyen QT. Exostoses and osteomas of the internal auditory canal. Laryngoscope. 2010; 120 Suppl 4:S215. PMID: 21225813.
        View in: PubMed
      17. Harris J. Inner ear medicine: targeted therapy. Editorial. Audiol Neurootol. 2009; 14(6):349. PMID: 19923804.
        View in: PubMed
      18. Wang X, Dellamary L, Fernandez R, Harrop A, Keithley EM, Harris J, Ye Q, Lichter J, LeBel C, Piu F. Dose-dependent sustained release of dexamethasone in inner ear cochlear fluids using a novel local delivery approach. Audiol Neurootol. 2009; 14(6):393-401. PMID: 19923809.
        View in: PubMed
      19. Ahmad ZK, Altuna X, Lopez JP, An Y, Wang-Rodriguez J, Juneja VR, Chen JS, Arandazi MJ, Aguilera J, Harris J, Ongkeko WM. p73 expression and function in vestibular schwannoma. Arch Otolaryngol Head Neck Surg. 2009 Jul; 135(7):662-9. PMID: 19620587.
        View in: PubMed
      20. Alexander TH, Weisman MH, Derebery JM, Espeland MA, Gantz BJ, Gulya AJ, Hammerschlag PE, Hannley M, Hughes GB, Moscicki R, Nelson RA, Niparko JK, Rauch SD, Telian SA, Brookhouser PE, Harris J. Safety of high-dose corticosteroids for the treatment of autoimmune inner ear disease. Otol Neurotol. 2009 Jun; 30(4):443-8. PMID: 19395984.
        View in: PubMed
      21. Crawley BK, Close A, Canto C, Harris J. Susac's syndrome: intratympanic therapy for hearing loss and a review of the literature. Laryngoscope. 2009 Jan; 119(1):141-4. PMID: 19117315.
        View in: PubMed
      22. Harris J, Ariessohn ML. Economic, family, and length-of-training issues that influence the selection of a clinician-scientist career path in otolaryngology. Otolaryngol Head Neck Surg. 2008 Jul; 139(1):100-4. PMID: 18585569.
        View in: PubMed
      23. Barkdull GC, Hondarrague Y, Meyer T, Harris J, Keithley EM. AM-111 reduces hearing loss in a guinea pig model of acute labyrinthitis. Laryngoscope. 2007 Dec; 117(12):2174-82. PMID: 18322422.
        View in: PubMed
      24. Harris J, Gong S. Comparison of hearing results of nitinol SMART stapes piston prosthesis with conventional piston prostheses: postoperative results of nitinol stapes prosthesis. Otol Neurotol. 2007 Aug; 28(5):692-5. PMID: 17414180.
        View in: PubMed
      25. Grandis JR, Battey JF, Califf RM, Chole RA, Gantz BJ, Gates GA, Gorelic L, Hannley MT, Hardwick KS, Harris J, Kapoor WN, Lai SY, Lalwani AK, Minor LB, Nadol JP, Post JC, Roland PS, Schechter AM, Schuller DE, Sklare DA, Wackym PA, Weber RS, Weymuller EA, Wolf GT, Woodson GE. Research education and training in otolaryngology: meeting summary and research opportunities. Otolaryngol Head Neck Surg. 2006 Sep; 135(3):361-7. PMID: 16949965.
        View in: PubMed
      26. Satoh H, Billings P, Firestein GS, Harris J, Keithley EM. Transforming growth factor beta expression during an inner ear immune response. Ann Otol Rhinol Laryngol. 2006 Jan; 115(1):81-8. PMID: 16466104.
        View in: PubMed
      27. Niparko JK, Wang NY, Rauch SD, Russell GB, Espeland MA, Pierce JJ, Bowditch S, Masuda A, Gulya AJ, Gantz BJ, Hughes GB, Brookhouser PE, Hannley MT, Telian SA, Harris J. Serial audiometry in a clinical trial of AIED treatment. Otol Neurotol. 2005 Sep; 26(5):908-17. PMID: 16151337.
        View in: PubMed
      28. Harris J, Chia S, Gamst A, Anderson JP. Meta-analysis of intratympanic gentamicin. Otol Neurotol. 2005 Sep; 26(5):1094. PMID: 16151367.
        View in: PubMed
      29. Benninger MS, Harris J, Jackler RK, Johnson JT, Johns MM, Kennedy DW, Ruben RJ, Sataloff RT, Smith RJ, Weber PC, Weber RS, Young ED. Consortium of otolaryngology-head and neck surgery journals to collaborate in maintenance of high ethical standards. Audiol Neurootol. 2005 Nov-Dec; 10(6):303-4. PMID: 16103640.
        View in: PubMed
      30. Barkdull GC, Vu C, Keithley EM, Harris J. Cochlear microperfusion: experimental evaluation of a potential new therapy for severe hearing loss caused by inflammation. Otol Neurotol. 2005 Jan; 26(1):19-26. PMID: 15699715.
        View in: PubMed
      31. Hashimoto S, Billings P, Harris J, Firestein GS, Keithley EM. Innate immunity contributes to cochlear adaptive immune responses. Audiol Neurootol. 2005 Jan-Feb; 10(1):35-43. PMID: 15567913.
        View in: PubMed
      32. Chia SH, Gamst AC, Anderson JP, Harris J. Intratympanic gentamicin therapy for Ménière's disease: a meta-analysis. Otol Neurotol. 2004 Jul; 25(4):544-52. PMID: 15241234.
        View in: PubMed
      33. Harris J, Weisman MH, Derebery JM, Espeland MA, Gantz BJ, Gulya AJ, Hammerschlag PE, Hannley M, Hughes GB, Moscicki R, Nelson RA, Niparko JK, Rauch SD, Telian SA, Brookhouser PE. Treatment of corticosteroid-responsive autoimmune inner ear disease with methotrexate: a randomized controlled trial. JAMA. 2003 Oct 8; 290(14):1875-83. PMID: 14532316.
        View in: PubMed
      34. Satoh H, Firestein GS, Billings PB, Harris J, Keithley EM. Proinflammatory cytokine expression in the endolymphatic sac during inner ear inflammation. J Assoc Res Otolaryngol. 2003 Jun; 4(2):139-47. PMID: 12943369.
        View in: PubMed
      35. Wang X, Truong T, Billings PB, Harris J, Keithley EM. Blockage of immune-mediated inner ear damage by etanercept. Otol Neurotol. 2003 Jan; 24(1):52-7. PMID: 12544029.
        View in: PubMed
      36. Satoh H, Firestein GS, Billings PB, Harris J, Keithley EM. Tumor necrosis factor-alpha, an initiator, and etanercept, an inhibitor of cochlear inflammation. Laryngoscope. 2002 Sep; 112(9):1627-34. PMID: 12352677.
        View in: PubMed
      37. Harris J, Mehta RP, Nadol JB. Malleus fixation: clinical and histopathologic findings. Ann Otol Rhinol Laryngol. 2002 Mar; 111(3 Pt 1):246-54. PMID: 11913685.
        View in: PubMed
      38. Harris J, Keithley EM. A case against spiral ligament atrophy as a cause of Ménière's disease. ORL J Otorhinolaryngol Relat Spec. 2002 Mar-Apr; 64(2):125-8. PMID: 12021504.
        View in: PubMed
      39. Ryan AF, Harris J, Keithley EM. Immune-mediated hearing loss: basic mechanisms and options for therapy. Acta Otolaryngol Suppl. 2002; (548):38-43. PMID: 12211356.
        View in: PubMed
      40. Ryan AF, Pak K, Low W, Battaglia A, Mullen L, Harris J, Keithley EM. Immunological damage to the inner ear: current and future therapeutic strategies. Adv Otorhinolaryngol. 2002; 59:66-74. PMID: 11885663.
        View in: PubMed
      41. Harris J, Heydt J, Keithley EM, Chen MC. Immunopathology of the inner ear: an update. Ann N Y Acad Sci. 1997 Dec 29; 830:166-78. PMID: 9616676.
        View in: PubMed
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