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    Edward Ball

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9500 Gilman Drive #0960
    CA La Jolla 92093
    Phone858-822-6600
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      Research Interests
      Dr. Ball’s research focuses on the development of monoclonal antibody (mAb)-targeted immunotherapy and its translation to the treatment of patients with malignancy. His lab produced mAbs to myeloid-associated antigens expressed on myeloid leukemia cells. These antibodies have been used clinically for the diagnosis and treatment of acute myeloid leukemia (AML).He has conducted multi-center clinical trials using antibody-mediated purging using the AML cells from the marrow of patients with leukemia prior to transplantation, after high dose chemotherapy. He has also developed in vivo therapeutics using an anti-CD15 mAb and a bispecific antibody. This bispecific antibody (251xH22) mediates antibody–directed cellular cytotoxicity(ADCC) of AML cells mediated by normal leukocyte cells including natural killer cells, monocytes and granulocytes. They determined that there are direct signals transduced by binding of the anti-CD33 monoclonal antibody that lead to death of AML cells mediated in part by the protein kinase Syk. This led to an investigator-initiated multi-center Phase I/II clinical trial combining 5-azacytidine (that increases Syk expression) and the anti-CD33 monoclonal antibody Mylotarg. His laboratory has also been working the generation of cytotoxic T cells in vitro in a novel culture system. Based on this pre-clinical work, they developed a clinical trial wherein patients with AML undergoing autologous stem cell transplantation are administered autologous cytotoxic T cells following the transplant with the goal of reducing the relapse rate. Dr. Ball is principal investigator on numerous clinical trials active at UCSD Medical Center ranging from Phase I investigator-initiated to Phase III trials. He has been a recipient of a NCI and NHLBI-sponsored UO1 grant from the NIH. He recently completed a study of a novel treatment of relapse following allogeneic stem cell transplantation. The infusion of a monoclonal antibody directed to the cytotoxic T lymphocyte antigen-4 (CTLA-4) was tested in series of patients with relapse for safety and efficacy. The study demonstrated the safety of this approach and some promising signs of efficacy. Dr. Ball has been the elected Secretary of the American Society of Blood and Marrow Transplantation and a member of the steering committee of the BMT Clinical Trials Network.

      Education and Training
      BS - Biochemistry, University of Maryland - 1968-1972
      MD - Case Western Reserve University - 1972-1976
      Resident - Hartford Hospital - 1976-1979
      Fellow - Hematology & Oncolog, University Hospitals of Cleveland - 1979-1981
      Fellow - Hematology & Oncology, Dartmouth- Hitchcock Medical Center - 1982-1983


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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Wang HY, McMahon C, Ali SM, Young LE, Yekezare S, Ross JS, Ball ED. Novel FNDC3B and MECOM fusion and WT1 L378fs* 7 frameshift mutation in an acute myeloid leukaemia patient with cytomorphological and immunophenotypic features reminiscent of acute promyelocytic leukaemia. Br J Haematol. 2016 Mar; 172(6):987-90. PMID: 26147192.
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      2. Ong E, Szedlak A, Kang Y, Smith P, Smith N, McBride M, Finlay D, Vuori K, Mason J, Ball ED, Piermarocchi C, Paternostro G. A scalable method for molecular network reconstruction identifies properties of targets and mutations in acute myeloid leukemia. J Comput Biol. 2015 Apr; 22(4):266-88. PMID: 25844667.
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      3. Zhong R, Li H, Messer K, Lane TA, Zhou J, Ball ED. Augmentation of autologous T cell reactivity with acute myeloid leukemia (AML) blasts by Toll-like receptor (TLR) agonists. Cancer Immunol Immunother. 2015 Jun; 64(6):737-44. PMID: 25795133.
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      4. Cunard R, Marquez II, Ball ED, Nelson CL, Corringham S, Clopton P, Sanchez AP, Lane T, Ward DM. Prophylactic red blood cell exchange for ABO-mismatched hematopoietic progenitor cell transplants. Transfusion. 2014 Jul; 54(7):1857-63. PMID: 24372185.
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      5. Johnson RL, Boisot S, Ball ED, Wang HY. A case of interdigitating dendritic cell sarcoma/histiocytic sarcoma - a diagnostic pitfall. Int J Clin Exp Pathol. 2013; 7(1):378-85. PMID: 24427360.
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      6. Armand P, Nagler A, Weller EA, Devine SM, Avigan DE, Chen YB, Kaminski MS, Holland HK, Winter JN, Mason JR, Fay JW, Rizzieri DA, Hosing CM, Ball ED, Uberti JP, Lazarus HM, Mapara MY, Gregory SA, Timmerman JM, Andorsky D, Or R, Waller EK, Rotem-Yehudar R, Gordon LI. Disabling Immune Tolerance by Programmed Death-1 Blockade With Pidilizumab After Autologous Hematopoietic Stem-Cell Transplantation for Diffuse Large B-Cell Lymphoma: Results of an International Phase II Trial. J Clin Oncol. 2013 Nov 20; 31(33):4199-206. PMID: 24127452.
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      7. Shaughnessy P, Uberti J, Devine S, Maziarz RT, Vose J, Micallef I, Jacobsen E, McCarty J, Stiff P, Artz A, Ball ED, Berryman R, Dugan M, Joyce R, Hsu FJ, Johns D, McSweeney P. Plerixafor and G-CSF for autologous stem cell mobilization in patients with NHL, Hodgkin's lymphoma and multiple myeloma: results from the expanded access program. Bone Marrow Transplant. 2013 Jun; 48(6):777-81. PMID: 23178544.
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      8. Ballen K, Mendizabal AM, Cutler C, Politikos I, Jamieson K, Shpall EJ, Dey BR, Attar E, McAfee S, Delaney C, McCarthy P, Ball ED, Kamble R, Avigan D, Maziarz RT, Ho VT, Koreth J, Alyea E, Soiffer R, Wingard JR, Boussiotis V, Spitzer TR, Antin JH. Phase II trial of parathyroid hormone after double umbilical cord blood transplantation. Biol Blood Marrow Transplant. 2012 Dec; 18(12):1851-8. PMID: 22766223.
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      9. Lor KW, Helmons PJ, Belew H, Lane JR, Ball ED. Plerixafor as first- and second-line strategies for autologous stem cell mobilization in patients with non-Hodgkin's lymphoma or multiple myeloma. Pharmacotherapy. 2012 Jul; 32(7):596-603. PMID: 22760691.
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      10. Heidary DK, Huang G, Boucher D, Ma J, Forster C, Grey R, Xu J, Arnost M, Choquette D, Chen G, Zhou JH, Yao YM, Ball ED, Namchuk M, Davies RJ, Henkel G. VX-322: a novel dual receptor tyrosine kinase inhibitor for the treatment of acute myelogenous leukemia. J Med Chem. 2012 Jan 26; 55(2):725-34. PMID: 22221201.
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      11. Armand P, Kim HT, Zhang MJ, Perez WS, Dal Cin PS, Klumpp TR, Waller EK, Litzow MR, Liesveld JL, Lazarus HM, Artz AS, Gupta V, Savani BN, McCarthy PL, Cahn JY, Schouten HC, Finke J, Ball ED, Aljurf MD, Cutler CS, Rowe JM, Antin JH, Isola LM, Di Bartolomeo P, Camitta BM, Miller AM, Cairo MS, Stockerl-Goldstein K, Sierra J, Savoie ML, Halter J, Stiff PJ, Nabhan C, Jakubowski AA, Bunjes DW, Petersdorf EW, Devine SM, Maziarz RT, Bornhauser M, Lewis VA, Marks DI, Bredeson CN, Soiffer RJ, Weisdorf DJ. Classifying cytogenetics in patients with acute myelogenous leukemia in complete remission undergoing allogeneic transplantation: a Center for International Blood and Marrow Transplant Research study. Biol Blood Marrow Transplant. 2012 Feb; 18(2):280-8. PMID: 21810400.
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      12. von Drygalski A, Tran TB, Messer K, Pu M, Corringham S, Nelson C, Ball ED. Obesity is an independent predictor of poor survival in metastatic breast cancer: retrospective analysis of a patient cohort whose treatment included high-dose chemotherapy and autologous stem cell support. Int J Breast Cancer. 2011; 2011:523276. PMID: 22295228.
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      13. Holman PR, Costello C, deMagalhaes-Silverman M, Corringham S, Castro J, Ball ED. Idiotype immunization following high-dose therapy and autologous stem cell transplantation for non-Hodgkin lymphoma. Biol Blood Marrow Transplant. 2012 Feb; 18(2):257-64. PMID: 21736867.
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      14. Cortes J, Kantarjian H, Ball ED, Dipersio J, Kolitz JE, Fernandez HF, Goodman M, Borthakur G, Baer MR, Wetzler M. Phase 2 randomized study of p53 antisense oligonucleotide (cenersen) plus idarubicin with or without cytarabine in refractory and relapsed acute myeloid leukemia. Cancer. 2012 Jan 15; 118(2):418-27. PMID: 21717444.
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      15. Dimsdale JE, Ball ED, Carrier E, Wallace M, Holman P, Mulroney C, Shaikh F, Natarajan L. Effect of eszopiclone on sleep, fatigue, and pain in patients with mucositis associated with hematologic malignancies. Support Care Cancer. 2011 Dec; 19(12):2015-20. PMID: 21116652.
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      16. Zhou J, Bashey A, Zhong R, Corringham S, Messer K, Pu M, Ma W, Chut T, Soiffer R, Mitrovich RC, Lowy I, Ball ED. CTLA-4 blockade following relapse of malignancy after allogeneic stem cell transplantation is associated with T cell activation but not with increased levels of T regulatory cells. Biol Blood Marrow Transplant. 2011 May; 17(5):682-92. PMID: 20713164.
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      17. Ball ED, Broome HE. Monoclonal antibodies in the treatment of hematologic malignancy. Best Pract Res Clin Haematol. 2010 Sep; 23(3):403-16. PMID: 21112039.
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      18. Espinosa-Aguilar L, Green JS, Forrest GN, Ball ED, Maziarz RT, Strasfeld L, Taplitz RA. Novel H1N1 influenza in hematopoietic stem cell transplantation recipients: two centers' experiences. Biol Blood Marrow Transplant. 2011 Apr; 17(4):566-73. PMID: 20708084.
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      19. Bashey A, Owzar K, Johnson JL, Edwards PS, Kelly M, Baxter-Lowe LA, Devine S, Farag S, Hurd D, Ball E, McCarthy P, Lister J, Shea TC, Linker C. Reduced-intensity conditioning allogeneic hematopoietic cell transplantation for patients with hematologic malignancies who relapse following autologous transplantation: a multi-institutional prospective study from the Cancer and Leukemia Group B (CALGB trial 100002). Biol Blood Marrow Transplant. 2011 Apr; 17(4):558-65. PMID: 20674758.
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      20. Messer K, Natarajan L, Ball ED, Lane TA. Toxicity-evaluation designs for phase I/II cancer immunotherapy trials. Stat Med. 2010 Mar 30; 29(7-8):712-20. PMID: 20213706.
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      21. Ball ED. Increasing the punch of reduced-intensity transplants. Blood. 2009 Dec 24; 114(27):5410-1. PMID: 20035041.
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      22. Trivedi M, Martinez S, Corringham S, Medley K, Ball ED. Review and revision of clinical practice of using G-CSF after autologous and allogeneic hematopoietic stem cell transplantation at UCSD. J Oncol Pharm Pract. 2011 Jun; 17(2):85-90. PMID: 20015929.
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      23. Jung AS, Holman PR, Castro JE, Carrier EK, Bashey A, Lane TA, Nelson CL, Pu M, Messer K, Corringham SM, Ball ED. Autologous hematopoietic stem cell transplantation as an intensive consolidation therapy for adult patients in remission from acute myelogenous leukemia. Biol Blood Marrow Transplant. 2009 Oct; 15(10):1306-13. PMID: 19747639.
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      24. Trivedi M, Martinez S, Corringham S, Medley K, Ball ED. Optimal use of G-CSF administration after hematopoietic SCT. Bone Marrow Transplant. 2009 Jun; 43(12):895-908. PMID: 19363527.
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      25. Bashey A, Medina B, Corringham S, Pasek M, Carrier E, Vrooman L, Lowy I, Solomon SR, Morris LE, Holland HK, Mason JR, Alyea EP, Soiffer RJ, Ball ED. CTLA4 blockade with ipilimumab to treat relapse of malignancy after allogeneic hematopoietic cell transplantation. Blood. 2009 Feb 12; 113(7):1581-8. PMID: 18974373.
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      26. Zhong RK, Lane TA, Ball ED. Generation of T-cell lines to autologous acute myeloid leukemia cells by competitive limiting dilution culture of acute myeloid leukemia mononuclear cells. Exp Hematol. 2008 Apr; 36(4):486-94. PMID: 18249062.
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      27. Bashey A, Donohue M, Liu L, Medina B, Corringham S, Ihasz A, Carrier E, Castro JE, Holman PR, Xu R, Law P, Ball ED, Lane TA. Peripheral blood progenitor cell mobilization with intermediate-dose cyclophosphamide, sequential granulocyte-macrophage-colony-stimulating factor and granulocyte-colony-stimulating factor, and scheduled commencement of leukapheresis in 225 patients undergoing autologous transplantation. Transfusion. 2007 Nov; 47(11):2153-60. PMID: 17958545.
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      28. Liu J, Malhotra R, Voltarelli J, Stracieri AB, Oliveira L, Simoes BP, Ball ED, Carrier E. Ovarian recovery after stem cell transplantation. Bone Marrow Transplant. 2008 Feb; 41(3):275-8. PMID: 17952128.
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      29. Nearman ZP, Wlodarski M, Jankowska AM, Howe E, Narvaez Y, Ball E, Maciejewski JP. Immunogenetic factors determining the evolution of T-cell large granular lymphocyte leukaemia and associated cytopenias. Br J Haematol. 2007 Jan; 136(2):237-48. PMID: 17156396.
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      30. Balaian L, Ball ED. Cytotoxic activity of gemtuzumab ozogamicin (Mylotarg) in acute myeloid leukemia correlates with the expression of protein kinase Syk. Leukemia. 2006 Dec; 20(12):2093-101. PMID: 17051243.
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      31. Nguyen DH, Ball ED, Varki A. Myeloid precursors and acute myeloid leukemia cells express multiple CD33-related Siglecs. Exp Hematol. 2006 Jun; 34(6):728-35. PMID: 16728277.
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      32. Zhou J, Chen J, Zhong R, Mokotoff M, Shultz LD, Ball ED. Targeting gastrin-releasing peptide receptors on small cell lung cancer cells with a bispecific molecule that activates polyclonal T lymphocytes. Clin Cancer Res. 2006 Apr 1; 12(7 Pt 1):2224-31. PMID: 16609038.
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      33. Zhong RK, Loken M, Lane TA, Ball ED. CTLA-4 blockade by a human MAb enhances the capacity of AML-derived DC to induce T-cell responses against AML cells in an autologous culture system. Cytotherapy. 2006; 8(1):3-12. PMID: 16627340.
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      34. Bashey A, Liu L, Ihasz A, Medina B, Corringham S, Keese K, Carrier E, Castro JE, Holman P, Lane TA, Hassidim K, Ball ED. Non-anthracycline based remission induction therapy for newly diagnosed patients with acute myeloid leukemia aged 60 or older. Leuk Res. 2006 Apr; 30(4):503-6. PMID: 16303178.
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      35. Kalaycio M, Rybicki L, Pohlman B, Sobecks R, Ball E, Cook D, Andresen S, Kuczkowski E, Bolwell B. CD8+ T-cell-depleted, matched unrelated donor, allogeneic bone marrow transplantation for advanced AML using busulfan-based preparative regimens. Bone Marrow Transplant. 2005 Feb; 35(3):247-52. PMID: 15580282.
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      36. Balaian L, Ball ED. Anti-CD33 monoclonal antibodies enhance the cytotoxic effects of cytosine arabinoside and idarubicin on acute myeloid leukemia cells through similarities in their signaling pathways. Exp Hematol. 2005 Feb; 33(2):199-211. PMID: 15676214.
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      37. Kamrava MR, Anderson EM, Kalunian K, Bashey A, Abshey A, Holman P, Medina B, Ball ED, Carrier E. T-cell depletion improves outcome after autologous stem cell transplant in patients with systemic lupus erythematosus (SLE). Bone Marrow Transplant. 2005 Jan; 35(2):205-6. PMID: 15543199.
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      38. Zhou J, Chen J, Mokotoff M, Ball ED. Targeting gastrin-releasing peptide receptors for cancer treatment. Anticancer Drugs. 2004 Nov; 15(10):921-7. PMID: 15514561.
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      39. Ball ED, Ho AD. Summary of the 12th international symposium on recent advances in stem cell transplantation. Exp Hematol. 2004 Oct; 32(10):881-4. PMID: 15504542.
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      40. Wang EH, Chen YA, Corringham S, Bashey A, Holman P, Ball ED, Carrier E. High-dose CEB vs BEAM with autologous stem cell transplant in lymphoma. Bone Marrow Transplant. 2004 Oct; 34(7):581-7. PMID: 15273714.
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      41. Balaian L, Ball ED. Inhibition of acute myeloid leukemia cell growth by mono-specific and bi-specific anti-CD33 x anti-CD64 antibodies. Leuk Res. 2004 Aug; 28(8):821-9. PMID: 15203280.
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      42. Zhong R, Law P, Wong D, Merzouk A, Salari H, Ball ED. Small peptide analogs to stromal derived factor-1 enhance chemotactic migration of human and mouse hematopoietic cells. Exp Hematol. 2004 May; 32(5):470-5. PMID: 15145215.
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      43. Lane TA, Bashey A, Carrier E, Holman P, Castro J, Mullen M, Ward DM, Ada O, Ball ED. Improving the efficiency of PBPC collection by pre-apheresis peripheral blood and mid-apheresis product measurements of CD34 cells. Cytotherapy. 2004; 6(4):318-27. PMID: 16146884.
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      44. Ball ED. Update in hematology. Ann Intern Med. 2003 Dec 2; 139(11):916-22. PMID: 14644894.
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      45. Zhou J, Chen J, Mokotoff M, Zhong R, Shultz LD, Ball ED. Bombesin/gastrin-releasing peptide receptor: a potential target for antibody-mediated therapy of small cell lung cancer. Clin Cancer Res. 2003 Oct 15; 9(13):4953-60. PMID: 14581370.
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      46. Tanner ML, Hoh CK, Bashey A, Holman P, Sun C, Broome HE, Lane T, Ball ED, Carrier E. FLAG chemotherapy followed by allogeneic stem cell transplant using nonmyeloablative conditioning induces regression of myelofibrosis with myeloid metaplasia. Bone Marrow Transplant. 2003 Sep; 32(6):581-5. PMID: 12953130.
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      47. Balaian L, Zhong RK, Ball ED. The inhibitory effect of anti-CD33 monoclonal antibodies on AML cell growth correlates with Syk and/or ZAP-70 expression. Exp Hematol. 2003 May; 31(5):363-71. PMID: 12763134.
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      48. Zhong RK, Rassenti LZ, Kipps TJ, Chen J, Law P, Yu JF, Ball ED. Sequential modulation of growth factors: a novel strategy for adoptive immunotherapy of acute myeloid leukemia. Biol Blood Marrow Transplant. 2002; 8(10):557-68. PMID: 12434951.
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      49. Castro JE, Ball ED. Development of allogeneic hematopoietic stem cell transplantation (HSCT). Cancer Treat Res. 2002; 110:1-37. PMID: 11908193.
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      50. Niimi T, Orita M, Okazawa-Igarashi M, Sakashita H, Kikuchi K, Ball E, Ichikawa A, Yamagiwa Y, Sakamoto S, Tanaka A, Tsukamoto S, Fujita S, Tatsuta K, Maeda Y, Chikauchi K. Design and synthesis of non-peptidic inhibitors for the Syk C-terminal SH2 domain based on structure-based in-silico screening. J Med Chem. 2001 Dec 20; 44(26):4737-40. PMID: 11741491.
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      51. Balaian L, Ball ED. Direct effect of bispecific anti-CD33 x anti-CD64 antibody on proliferation and signaling in myeloid cells. Leuk Res. 2001 Dec; 25(12):1115-25. PMID: 11684286.
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      52. Voltarelli JC, Ahmed H, Paton EJ, Stracieri AB, Holman P, Bashey A, Coutinho M, Simoes BP, Ball ED, Carrier E. Beneficial effect of intravenous lidocaine in cutaneous chronic graft-versus-host disease secondary to donor lymphocyte infusion. Bone Marrow Transplant. 2001 Jul; 28(1):97-9. PMID: 11498752.
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      53. Mokotoff M, Mocarski YM, Gentsch BL, Miller MR, Zhou JH, Chen J, Ball ED. Caution in the use of 2-iminothiolane (Traut's reagent) as a cross-linking agent for peptides. The formation of N-peptidyl-2-iminothiolanes with bombesin (BN) antagonist (D-Trp(6),Leu(13)-psi[CH(2)NH]-Phe(14))BN(6-14) and D-Trp-Gln-Trp-NH(2). J Pept Res. 2001 May; 57(5):383-9. PMID: 11350598.
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      54. Chen J, Zhou JH, Ball ED. Characterization of a new monoclonal antibody 6G7 that recognizes a unique antigen on myeloid and lymphoid cells. J Hematother Stem Cell Res. 2001 Apr; 10(2):237-46. PMID: 11359671.
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      55. Zhong RK, van de Winkel JG, Thepen T, Schultz LD, Ball ED. Cytotoxicity of anti-CD64-ricin a chain immunotoxin against human acute myeloid leukemia cells in vitro and in SCID mice. J Hematother Stem Cell Res. 2001 Feb; 10(1):95-105. PMID: 11276363.
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      56. Bashey A, Sundaram S, Corringham S, Jones V, Lancaster D, Silva-Gietzen J, Law P, Ball ED. Use of capecitabine as first-line therapy in patients with metastatic breast cancer relapsing after high-dose chemotherapy and autologous stem cell support. Clin Oncol (R Coll Radiol). 2001; 13(6):434-7. PMID: 11824880.
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      57. Ball ED, Wilson J, Phelps V, Neudorf S. Autologous bone marrow transplantation for acute myeloid leukemia in remission or first relapse using monoclonal antibody-purged marrow: results of phase II studies with long-term follow-up. Bone Marrow Transplant. 2000 Apr; 25(8):823-9. PMID: 10808202.
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      58. deMagalhaes-Silverman M, Donnenberg A, Lembersky B, Elder E, Lister J, Rybka W, Whiteside T, Ball E. Posttransplant adoptive immunotherapy with activated natural killer cells in patients with metastatic breast cancer. J Immunother. 2000 Jan; 23(1):154-60. PMID: 10687148.
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      59. Bashey A, Corringham S, Gilpin E, Fields KK, Smilee RC, DeFrancisco C, Santos-Ada O, Holman P, Carrier E, Ho AD, Lane TA, Ball ED, Janssen WE, Law P. Simultaneous administration of G-CSF and GM-CSF for re-mobilization in patients with inadequate initial progenitor cell collections for autologous transplantation. Cytotherapy. 2000; 2(3):195-200. PMID: 12042042.
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      60. Ball ED. Ex vivo purging and cell expansion. J Hematother Stem Cell Res. 1999 Oct; 8(5):457-8. PMID: 10791896.
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      61. Zhong RK, Donnenberg AD, Zhang HF, Watkins S, Zhou JH, Ball ED. Human blood dendritic cell-like B cells isolated by the 5G9 monoclonal antibody reactive with a novel 220-kDa antigen. J Immunol. 1999 Aug 1; 163(3):1354-62. PMID: 10415035.
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      62. de Magalhaes-Silverman M, Donnenberg AD, Lister J, Rybka W, Wilson J, Ball E. Factors influencing mobilization and engraftment in patients with metastatic breast cancer undergoing PBSC transplantation. J Hematother. 1999 Apr; 8(2):167-72. PMID: 10349910.
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      63. Takiyama N, Mohney T, Swaney W, Bahnson AB, Rice E, Beeler M, Scheirer-Fochler S, Ball ED, Barranger JA. Comparison of methods for retroviral mediated transfer of glucocerebrosidase gene to CD34+ hematopoietic progenitor cells. Eur J Haematol. 1998 Jul; 61(1):1-6. PMID: 9688285.
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      64. Steinman RA, Huang J, Yaroslavskiy B, Goff JP, Ball ED, Nguyen A. Regulation of p21(WAF1) expression during normal myeloid differentiation. Blood. 1998 Jun 15; 91(12):4531-42. PMID: 9616149.
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      65. White SM, Ball ED, Ehmann WC, Rao AS, Tweardy DJ. Increased expression of the differentiation-defective granulocyte colony-stimulating factor receptor mRNA isoform in acute myelogenous leukemia. Leukemia. 1998 Jun; 12(6):899-906. PMID: 9639418.
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      66. de Magalhaes-Silverman M, Simpson J, Ball E. Pneumoperitoneum without peritonitis after allogeneic peripheral blood stem cell transplantation. Bone Marrow Transplant. 1998 Jun; 21(11):1153-4. PMID: 9645580.
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      67. deMagalhaes-Silverman M, Hammert L, Lembersky B, Lister J, Rybka W, Ball E. High-dose chemotherapy and autologous stem cell support followed by post-transplant doxorubicin and taxol as initial therapy for metastatic breast cancer: hematopoietic tolerance and efficacy. Bone Marrow Transplant. 1998 Jun; 21(12):1207-11. PMID: 9674853.
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      68. Shpall EJ, LeMaistre CF, Holland K, Ball E, Jones RB, Saral R, Jacobs C, Heimfeld S, Berenson R, Champlin R. A prospective randomized trial of buffy coat versus CD34-selected autologous bone marrow support in high-risk breast cancer patients receiving high-dose chemotherapy. Blood. 1997 Dec 1; 90(11):4313-20. PMID: 9373242.
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      69. Hammert LC, Ball ED. Purging marrow or peripheral blood stem cells for autografting. Curr Opin Hematol. 1997 Nov; 4(6):423-8. PMID: 9359000.
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      70. Davis BH, Foucar K, Szczarkowski W, Ball E, Witzig T, Foon KA, Wells D, Kotylo P, Johnson R, Hanson C, Bessman D. U.S.-Canadian Consensus recommendations on the immunophenotypic analysis of hematologic neoplasia by flow cytometry: medical indications. Cytometry. 1997 Oct 15; 30(5):249-63. PMID: 9383099.
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      71. Reynolds WF, Chang E, Douer D, Ball ED, Kanda V. An allelic association implicates myeloperoxidase in the etiology of acute promyelocytic leukemia. Blood. 1997 Oct 1; 90(7):2730-7. PMID: 9326240.
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      72. Neudorf SM, Rybka W, Ball E, Blatt J, Bloom E, Corey S, deMagalhaes-Silverman M, Koehler M, Lister J, Mierski J, Mirro J, Pincus S, Wilson J, Wollman M, Donnenberg AD. The use of counterflow centrifugal elutriation for the depletion of T cells from unrelated donor bone marrow. J Hematother. 1997 Aug; 6(4):351-9. PMID: 9377073.
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      73. deMagalhaes-Silverman M, Donnenberg A, Hammert L, Lister J, Myers D, Simpson J, Ball E. Induction of graft-versus-leukemia effect in a patient with chronic lymphocytic leukemia. Bone Marrow Transplant. 1997 Jul; 20(2):175-7. PMID: 9244424.
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      74. Hammert LC, Ball ED. Purging autologous bone marrow with monoclonal antibodies for transplantation in acute myelogenous leukemia. Blood Rev. 1997 Jun; 11(2):80-90. PMID: 9242991.
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      75. Kozii R, Wilson J, Persichetti J, Phelps V, Ball SE, Ball ED. Thy-1 expression on blast cells from adult patients with acute myeloid leukemia. Leuk Res. 1997 May; 21(5):381-5. PMID: 9225063.
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      76. Lister J, Simpson JK, deMagalhaes-Silverman MM, Rybka WB, Donnenberg AD, Myers DJ, Ball ED. Allogeneic peripheral blood stem cell transplant for myelodysplasia after chemotherapy for post-transplant lymphoma in a cardiac transplant recipient at 10 years. Bone Marrow Transplant. 1997 May; 19(9):943-5. PMID: 9156271.
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      77. de Magalhaes-Silverman M, Lister J, Rybka W, Wilson J, Ball E. Busulfan and cyclophosphamide (BU/CY2) as preparative regimen for patients with lymphoma. Bone Marrow Transplant. 1997 Apr; 19(8):777-81. PMID: 9134168.
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      78. deMagalhaes-Silverman M, Bloom E, Lembersky B, Lister J, Pincus S, Rybka W, Voloshin M, Wilson J, Ball E. High-dose chemotherapy and autologous stem cell support followed by posttransplantation doxorubicin as initial therapy for metastatic breast cancer. Clin Cancer Res. 1997 Feb; 3(2):193-7. PMID: 9815672.
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      79. Kiss JE, Rybka WB, Winkelstein A, deMagalhaes-Silverman M, Lister J, D'Andrea P, Ball ED. Relationship of CD34+ cell dose to early and late hematopoiesis following autologous peripheral blood stem cell transplantation. Bone Marrow Transplant. 1997 Feb; 19(4):303-10. PMID: 9051238.
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      80. Chakraborty A, White SM, Schaefer TS, Ball ED, Dyer KF, Tweardy DJ. Granulocyte colony-stimulating factor activation of Stat3 alpha and Stat3 beta in immature normal and leukemic human myeloid cells. Blood. 1996 Oct 1; 88(7):2442-9. PMID: 8839834.
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      81. Jurlander J, Caligiuri MA, Ruutu T, Baer MR, Strout MP, Oberkircher AR, Hoffmann L, Ball ED, Frei-Lahr DA, Christiansen NP, Block AM, Knuutila S, Herzig GP, Bloomfield CD. Persistence of the AML1/ETO fusion transcript in patients treated with allogeneic bone marrow transplantation for t(8;21) leukemia. Blood. 1996 Sep 15; 88(6):2183-91. PMID: 8822938.
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      82. Henderson RA, Nimgaonkar MT, Watkins SC, Robbins PD, Ball ED, Finn OJ. Human dendritic cells genetically engineered to express high levels of the human epithelial tumor antigen mucin (MUC-1). Cancer Res. 1996 Aug 15; 56(16):3763-70. PMID: 8706022.
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      83. Zhong RK, Donnenberg AD, Shultz LD, Swerdlow SH, Lee E, Rubin J, Kozii R, Chen J, Griffin DL, Wilson J, Ball ED. Evaluation of monoclonal antibody-mediated anti-acute myeloid leukemia immunotherapy in a SCID/hu model. Leuk Res. 1996 Jul; 20(7):581-9. PMID: 8795692.
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      84. Silla LM, Pincus SM, Locker JD, Glover J, Elder EM, Donnenberg AD, Nardi NB, Bryant J, Ball ED, Whiteside TL. Generation of activated natural killer (A-NK) cells in patients with chronic myelogenous leukaemia and their role in the in vitro disappearance of BCR/abl-positive targets. Br J Haematol. 1996 May; 93(2):375-85. PMID: 8639431.
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      85. deMagalhaes-Silverman M, Rybka WB, Lembersky B, Bloom EJ, Lister J, Pincus SM, Voloshin M, Wilson J, Ball ED. High-dose cyclophosphamide, carboplatin, and etoposide with autologous stem cell rescue in patients with breast cancer. Am J Clin Oncol. 1996 Apr; 19(2):169-73. PMID: 8610643.
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      86. deMagalhaes-Silverman M, Bloom EJ, Donnenberg A, Lister J, Pincus S, Rybka WB, Ball ED. Toxicity of busulfan and cyclophosphamide (BU/CY2) in patients with hematologic malignancies. Bone Marrow Transplant. 1996 Mar; 17(3):329-33. PMID: 8704682.
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      87. Nimgaonkar M, Kemp A, Lancia J, Ball ED. A combination of CD34 selection and complement-mediated immunopurging (anti-CD15 monoclonal antibody) eliminates tumor cells while sparing normal progenitor cells. J Hematother. 1996 Feb; 5(1):39-48. PMID: 8646480.
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      88. Mannion-Henderson J, Kemp A, Mohney T, Nimgaonkar M, Lancia J, Beeler MT, Mierski J, Bahnson AB, Ball ED, Barranger JA. Efficient retroviral mediated transfer of the glucocerebrosidase gene in CD34+ enriched umbilical cord blood human hematopoietic progenitors. Exp Hematol. 1995 Dec; 23(14):1628-32. PMID: 8542957.
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      89. Nimgaonkar M, Mierski J, Beeler M, Kemp A, Lancia J, Mannion-Henderson J, Mohney T, Bahnson A, Rice E, Ball ED, et al. Cytokine mobilization of peripheral blood stem cells in patients with Gaucher disease with a view to gene therapy. Exp Hematol. 1995 Dec; 23(14):1633-41. PMID: 8542958.
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      90. Chen J, Zhou JH, Ball ED. Monocyte-mediated lysis of acute myeloid leukemia cells in the presence of the bispecific antibody 251 x 22 (anti-CD33 x anti-CD64). Clin Cancer Res. 1995 Nov; 1(11):1319-25. PMID: 9815927.
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      91. Fanger MW, Ball ED, Drakeman DL. Comments on the Fourth International Conference on Bispecific Antibodies and Cellular Cytotoxicity, Duck Key, Florida, March 1-5, 1995. J Hematother. 1995 Oct; 4(5):345-9. PMID: 8581367.
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      92. Chen J, Zhou JH, Mokotoff M, Fanger MW, Ball ED. Lysis of small cell carcinoma of the lung (SCCL) cells by cytokine-activated monocytes and natural killer cells in the presence of bispecific immunoconjugates containing a gastrin-releasing peptide (GRP) analog or a GRP antagonist. J Hematother. 1995 Oct; 4(5):369-76. PMID: 8581371.
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      93. Zhong RK, Kozii R, Ball ED. Homologous restriction of complement-mediated cell lysis can be markedly enhanced by blocking decay-accelerating factor. Br J Haematol. 1995 Oct; 91(2):269-74. PMID: 8547061.
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      94. Ball ED, Selvaggi K, Hurd D, Herzig R, Clark L, Malley V, Persichetti J, deMagelhaus-Silverman M. Phase I clinical trial of serotherapy in patients with acute myeloid leukemia with an immunoglobulin M monoclonal antibody to CD15. Clin Cancer Res. 1995 Sep; 1(9):965-72. PMID: 9816068.
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      95. Silla LM, Whiteside TL, Ball ED. The role of natural killer cells in the treatment of chronic myeloid leukemia. J Hematother. 1995 Aug; 4(4):269-79. PMID: 7489141.
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      96. Lister J, Rybka WB, Donnenberg AD, deMagalhaes-Silverman M, Pincus SM, Bloom EJ, Elder EM, Ball ED, Whiteside TL. Autologous peripheral blood stem cell transplantation and adoptive immunotherapy with activated natural killer cells in the immediate posttransplant period. Clin Cancer Res. 1995 Jun; 1(6):607-14. PMID: 9816022.
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      97. Davey FR, Abraham N, Brunetto VL, MacCallum JM, Nelson DA, Ball ED, Griffin JD, Baer MR, Wurster-Hill D, Mayer RJ, et al. Morphologic characteristics of erythroleukemia (acute myeloid leukemia; FAB-M6): a CALGB study. Am J Hematol. 1995 May; 49(1):29-38. PMID: 7741135.
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      98. Ball ED. Introduction: workshop summary of the CD15 monoclonal antibody panel from the Fifth International Workshop on Leukocyte Antigens. Eur J Morphol. 1995 Apr; 33(2):95-100. PMID: 7488522.
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      99. Silla LM, Chen J, Zhong RK, Whiteside TL, Ball ED. Potentiation of lysis of leukaemia cells by a bispecific antibody to CD33 and CD16 (Fc gamma RIII) expressed by human natural killer (NK) cells. Br J Haematol. 1995 Apr; 89(4):712-8. PMID: 7772507.
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      100. Rybka WB, Fontes PA, Rao AS, Winkelstein A, Ricordi C, Ball ED, Starzl TE. Hematopoietic progenitor cell content of vertebral body marrow used for combined solid organ and bone marrow transplantation. Transplantation. 1995 Mar 27; 59(6):871-4. PMID: 7701582.
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      101. Nimgaonkar MT, Roscoe RA, Persichetti J, Rybka WB, Winkelstein A, Ball ED. A unique population of CD34+ cells in cord blood. Stem Cells. 1995 Mar; 13(2):158-66. PMID: 7540469.
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      102. Memon M, deMagalhaes-Silverman M, Bloom EJ, Lister J, Myers DJ, Pincus SM, Rybka WB, Ball ED. Reversible cyclosporine-induced cortical blindness in allogeneic bone marrow transplant recipients. Bone Marrow Transplant. 1995 Feb; 15(2):283-6. PMID: 7773219.
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      103. Ricordi C, Tzakis AG, Rybka WB, Fontes P, Ball ED, Trucco M, Kocova M, Triulzi D, McMichael J, Doyle H, et al. Xenotransplantation of hematopoietic cells resistant to HIV as a potential treatment for patients with AIDS. Transplant Proc. 1994 Jun; 26(3):1302-3. PMID: 7913262.
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      104. Bahnson AB, Nimgaonkar M, Fei Y, Boggs SS, Robbins PD, Ohashi T, Dunigan J, Li J, Ball ED, Barranger JA. Transduction of CD34+ enriched cord blood and Gaucher bone marrow cells by a retroviral vector carrying the glucocerebrosidase gene. Gene Ther. 1994 May; 1(3):176-84. PMID: 7584079.
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      105. Nimgaonkar MT, Bahnson AB, Boggs SS, Ball ED, Barranger JA. Transduction of mobilized peripheral blood CD34+ cells with the glucocerebrosidase cDNA. Gene Ther. 1994 May; 1(3):201-7. PMID: 7584082.
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      106. Zhong RK, Donnenberg AD, Rubin J, Ball ED. Differential effect of 4-hydroperoxycyclophosphamide and antimyeloid monoclonal antibodies on T and natural killer cells during bone marrow purging. Blood. 1994 Apr 15; 83(8):2345-51. PMID: 7512845.
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      107. Neubauer A, Dodge RK, George SL, Davey FR, Silver RT, Schiffer CA, Mayer RJ, Ball ED, Wurster-Hill D, Bloomfield CD, et al. Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia. Blood. 1994 Mar 15; 83(6):1603-11. PMID: 8123851.
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      108. Ricordi C, Tzakis AG, Zeevi A, Rybka WB, Demetris AJ, Fontes PA, Nalesnik MA, Trucco M, Ukah FO, Ball ED, et al. Reversal of graft-versus-host disease with infusion of autologous bone marrow. Cell Transplant. 1994 Mar-Apr; 3(2):187-92. PMID: 8012734.
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      109. Rubin J, Malley V, Ball ED. A combination of anti-CD15 monoclonal antibody PM-81 and 4-hydroperoxycyclophosphamide augments tumor cytotoxicity while sparing normal progenitor cells. J Hematother. 1994; 3(2):121-7. PMID: 7922015.
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      110. Ball ED, Rybka WB. Autologous bone marrow transplantation for adult acute leukemia. Hematol Oncol Clin North Am. 1993 Feb; 7(1):201-31. PMID: 8449859.
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      111. Taylor JA, Sandler DP, Bloomfield CD, Shore DL, Ball ED, Neubauer A, McIntyre OR, Liu E. ras oncogene activation and occupational exposures in acute myeloid leukemia. J Natl Cancer Inst. 1992 Nov 4; 84(21):1626-32. PMID: 1433344.
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      112. Howell AL, Stukel TA, Bloomfield CD, Ball ED. Predictive value of flow cytometric analyses of blast cells in assessing the phenotype of the leukemia colony-forming cell (L-CFC) population in acute myeloid leukemia. Bone Marrow Transplant. 1992 Sep; 10(3):261-6. PMID: 1422480.
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      113. Ericson SG, Colby E, Welch L, Ball ED. Engraftment of leukocyte subsets following autologous bone marrow transplantation in acute myeloid leukemia using anti-myeloid (CD14 and CD15) monoclonal antibody-purged bone marrow. Bone Marrow Transplant. 1992 Feb; 9(2):129-37. PMID: 1373982.
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      114. Ball ED, Mills L, Hurd D, McMillan R, Gingrich R. Autologous bone marrow transplantation for acute myeloid leukemia using monoclonal antibody-purged bone marrow. Prog Clin Biol Res. 1992; 377:97-110; discussion 111. PMID: 1438450.
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      115. Ball ED, Guyre PM, Mills L, Fisher J, Dinces NB, Fanger MW. Initial trial of bispecific antibody-mediated immunotherapy of CD15-bearing tumors: cytotoxicity of human tumor cells using a bispecific antibody comprised of anti-CD15 (MoAb PM81) and anti-CD64/Fc gamma RI (MoAb 32). J Hematother. 1992; 1(1):85-94. PMID: 1365020.
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      116. Vaickus L, Ball ED, Foon KA. Immune markers in hematologic malignancies. Crit Rev Oncol Hematol. 1991 Dec; 11(4):267-97. PMID: 1777090.
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      117. Ball ED, Schwarz LM, Bloomfield CD. Expression of the CD15 antigen on normal and leukemic myeloid cells: effects of neuraminidase and variable detection with a panel of monoclonal antibodies. Mol Immunol. 1991 Sep; 28(9):951-8. PMID: 1681429.
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      118. Wurster-Hill DH, Vredenburgh JJ, Davis BH, Mills LE, Ball ED. Isodicentric chromosome 18q as sole abnormality in a histologically normal bone marrow from a patient with diffuse large-cell non-Hodgkin's lymphoma. Cancer Genet Cytogenet. 1991 Jul 15; 54(2):233-7. PMID: 1884356.
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      119. Ball ED, Powers FJ, Vredenburgh JJ, Heath CA, Converse AO. Purging of small cell lung cancer cells from bone marrow using immunomagnetic beads and a flow-through device. Bone Marrow Transplant. 1991 Jul; 8(1):35-40. PMID: 1655139.
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      120. Ball ED, Davis RB, Griffin JD, Mayer RJ, Davey FR, Arthur DC, Wurster-Hill D, Noll W, Elghetany MT, Allen SL, et al. Prognostic value of lymphocyte surface markers in acute myeloid leukemia. Blood. 1991 May 15; 77(10):2242-50. PMID: 1709379.
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      121. Vredenburgh JJ, Simpson W, Memoli VA, Ball ED. Reactivity of anti-CD15 monoclonal antibody PM-81 with breast cancer and elimination of breast cancer cells from human bone marrow by PM-81 and immunomagnetic beads. Cancer Res. 1991 May 1; 51(9):2451-5. PMID: 1673088.
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      122. Wilson KE, Ball E, Stasny P, Capra JD. Allorecognition of HLA DR2 and DR5 molecules by V-beta-8-positive T-cell clones. Scand J Immunol. 1991 Feb; 33(2):131-9. PMID: 2017654.
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      123. Ball ED. Immunophenotyping of acute myeloid leukemia cells. Clin Lab Med. 1990 Dec; 10(4):721-36. PMID: 2272171.
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      124. Vredenburgh JJ, Ball ED. Elimination of small cell carcinoma of the lung from human bone marrow by monoclonal antibodies and immunomagnetic beads. Cancer Res. 1990 Nov 15; 50(22):7216-20. PMID: 2171759.
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      125. Döhner H, Arthur DC, Ball ED, Sobol RE, Davey FR, Lawrence D, Gordon L, Patil SR, Surana RB, Testa JR, et al. Trisomy 13: a new recurring chromosome abnormality in acute leukemia. Blood. 1990 Oct 15; 76(8):1614-21. PMID: 1698482.
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      126. Ball ED, Vredenburgh JJ, Mills LE, Cornwell GG, Schwarz L, Howell AL, Troy K. Autologous bone marrow transplantation for acute myeloid leukemia following in vitro treatment with neuraminidase and monoclonal antibodies. Bone Marrow Transplant. 1990 Oct; 6(4):277-80. PMID: 1982228.
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      127. Fyrberg E, Kelly M, Ball E, Fyrberg C, Reedy MC. Molecular genetics of Drosophila alpha-actinin: mutant alleles disrupt Z disc integrity and muscle insertions. J Cell Biol. 1990 Jun; 110(6):1999-2011. PMID: 2112549.
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      128. Ball ED, Mills LE, Cornwell GG, Davis BH, Coughlin CT, Howell AL, Stukel TA, Dain BJ, McMillan R, Spruce W, et al. Autologous bone marrow transplantation for acute myeloid leukemia using monoclonal antibody-purged bone marrow. Blood. 1990 Mar 1; 75(5):1199-206. PMID: 2306522.
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      129. Howell AL, Stukel TA, Bloomfield CD, Davey FR, Ball ED. Induction of differentiation in blast cells and leukemia colony-forming cells from patients with acute myeloid leukemia. Blood. 1990 Feb 1; 75(3):721-9. PMID: 2105108.
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      130. Mills LE, Ball ED, Howell AL, Cornwell GG, Thompson L, Spruce W, Miller WE, McMillan R. Efficacy of bone marrow purging in AML using monoclonal antibodies and complement. Prog Clin Biol Res. 1990; 333:165-70. PMID: 2308980.
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      131. Mills LE, Cornwell GG, Ball ED. Autologous bone marrow transplantation in the treatment of acute myeloid leukemia: the Dartmouth experience and a review of literature. Cancer Invest. 1990; 8(2):181-90. PMID: 2205335.
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      132. Ball ED, Mills LE, Neubauer A, Liu E. Detection of minimal acute myeloid leukemia cells in bone marrow by probing for mutated ras oncogenes using the polymerase chain reaction. Prog Clin Biol Res. 1990; 333:499-506. PMID: 2408063.
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      133. Davis BH, Bigelow N, Ball ED, Mills L, Cornwell GG. Utility of flow cytometric reticulocyte quantification as a predictor of engraftment in autologous bone marrow transplantation. Am J Hematol. 1989 Oct; 32(2):81-7. PMID: 2474249.
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      134. Kimura H, Buescher ES, Ball ED, Marcus DM. Restricted usage of VH and V kappa genes by murine monoclonal antibodies against 3-fucosyllactosamine. Eur J Immunol. 1989 Sep; 19(9):1741-6. PMID: 2571506.
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      135. Ball ED, McDermott J, Griffin JD, Davey FR, Davis R, Bloomfield CD. Expression of the three myeloid cell-associated immunoglobulin G Fc receptors defined by murine monoclonal antibodies on normal bone marrow and acute leukemia cells. Blood. 1989 May 15; 73(7):1951-6. PMID: 2469504.
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      136. Ball ED, Keefe KA, McDermott JM. Effects of anti-myeloid antibodies on the generation of hematopoietic colony-forming units in long-term bone marrow culture. Bone Marrow Transplant. 1989 May; 4(3):309-15. PMID: 2659116.
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      137. Howell AL, Fogg-Leach M, Davis BH, Ball ED. Continuous infusion of complement by an automated cell processor enhances cytotoxicity of monoclonal antibody sensitized leukemia cells. Bone Marrow Transplant. 1989 May; 4(3):317-22. PMID: 2659117.
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      138. Memoli VA, Jordan AG, Ball ED. A novel monoclonal antibody, SCCL 175, with specificity for small cell neuroendocrine carcinoma of the lung. Cancer Res. 1988 Dec 15; 48(24 Pt 1):7319-22. PMID: 2847869.
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      139. Ball ED. In vitro purging of bone marrow for autologous marrow transplantation in acute myelogenous leukemia using myeloid-specific monoclonal antibodies. Bone Marrow Transplant. 1988 Sep; 3(5):387-92. PMID: 3056546.
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      140. Myers DE, Uckun FM, Ball ED, Vallera DA. Immunotoxins for ex vivo marrow purging in autologous bone marrow transplantation for acute nonlymphocytic leukemia. Transplantation. 1988 Aug; 46(2):240-5. PMID: 2457265.
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      141. Ball ED, Howell AL. Monoclonal antibodies to carbohydrate antigens in autologous bone marrow transplantation. J Cell Biochem. 1988 Apr; 36(4):445-52. PMID: 3288649.
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      142. Howell AL, Miller R, Keefe KA, McIntyre OR, Stockner M, Sullivan R, Hibbert SR, Noelle RJ, Ball ED. Distribution of the 124-kd antigen defined by monoclonal antibody AML-1-99 on normal and leukemic myeloid cells. Exp Hematol. 1988 Mar; 16(3):176-83. PMID: 3422192.
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      143. Kimura H, Cook R, Meek K, Umeda M, Ball E, Capra JD, Marcus DM. Sequences of the VH and VL regions of murine monoclonal antibodies against 3-fucosyllactosamine. J Immunol. 1988 Feb 15; 140(4):1212-7. PMID: 2893825.
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      144. Vredenburgh JJ, McIntyre OR, Cornwell GG, Ball ED, Cornell CJ, Mills LE, O'Donnell JF. Mitoxantrone in relapsed or refractory acute nonlymphocytic leukemia. Med Pediatr Oncol. 1988; 16(3):187-9. PMID: 3380061.
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      145. Ball ED, Keefe KA, Colby E. Expression of antigens associated with small cell carcinoma of the lung on hematopoietic progenitor cells. Cancer Res. 1987 Dec 15; 47(24 Pt 1):6556-9. PMID: 2824035.
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      146. Reading CL, Thomas MW, Hickey CM, Chandran M, Tindle S, Ball ED, Poynton CH, Dicke KA. Magnetic affinity colloid (MAC) cell separation of leukemia cells from autologous bone marrow aspirates. Leuk Res. 1987; 11(12):1067-77. PMID: 3695563.
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      147. Ball ED, Mills LE, Coughlin CT, Beck JR, Cornwell GG. Autologous bone marrow transplantation in acute myelogenous leukemia: in vitro treatment with myeloid cell-specific monoclonal antibodies. Blood. 1986 Dec; 68(6):1311-5. PMID: 3535927.
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      148. Ball ED, Howell AL, Shen L. Gamma interferon and 1,25 dihydroxyvitamin D3 cooperate in the induction of monocytoid differentiation but not in the functional activation of the HL-60 promyelocytic leukemia cell line. Exp Hematol. 1986 Dec; 14(11):998-1005. PMID: 3096754.
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      149. Spitalnik SL, Spitalnik PF, Civin CI, Ball ED, Schwartz JF, Ginsburg V. Sialylated glycolipid antigens on human leukemic cell lines. Exp Hematol. 1986 Aug; 14(7):643-7. PMID: 3732420.
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      150. Ball ED, Sorenson GD, Pettengill OS. Expression of myeloid and major histocompatibility antigens on small cell carcinoma of the lung cell lines analyzed by cytofluorography: modulation by gamma-interferon. Cancer Res. 1986 May; 46(5):2335-9. PMID: 3008987.
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      151. Umeda M, Diego I, Ball ED, Marcus DM. Idiotypic determinants of monoclonal antibodies that bind to 3-fucosyllactosamine. J Immunol. 1986 Apr 1; 136(7):2562-7. PMID: 2419441.
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      152. Ball ED, Nichols KE, Pettengill OS, Sorenson GD, Fanger MW. Lysis of small cell carcinoma of the lung tumor cell lines by gamma interferon-activated allogeneic peripheral blood mononuclear cells: abrogation of killing by pretreatment of tumor cells with gamma interferon. Cancer Immunol Immunother. 1986; 22(3):211-6. PMID: 3015408.
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      153. Maliszewski CR, Ball ED, Graziano RF, Fanger MW. Isolation and characterization of My23, a myeloid cell-derived antigen reactive with the monoclonal antibody AML-2-23. J Immunol. 1985 Sep; 135(3):1929-36. PMID: 3894519.
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      154. Howell AL, Ball ED. Monoclonal antibody-mediated cytotoxicity of human myeloid leukemia cells: an in vitro model for estimating efficiency and optimal conditions for cytolysis. Blood. 1985 Sep; 66(3):649-54. PMID: 3861203.
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      155. Rigby WF, Shen L, Ball ED, Fanger MW. 1,25-Dihydroxyvitamin D3 induces a myelomonocytic phenotype with enhanced effector cell function in the HL-60 promyelocytic leukemia cell line. Mol Immunol. 1985 May; 22(5):567-72. PMID: 3860730.
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      156. Rigby WF, Ball ED, Guyre PM, Fanger MW. The effects of recombinant-DNA-derived interferons on the growth of myeloid progenitor cells. Blood. 1985 Apr; 65(4):858-61. PMID: 2579688.
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      157. Sabbath KD, Ball ED, Larcom P, Davis RB, Griffin JD. Heterogeneity of clonogenic cells in acute myeloblastic leukemia. J Clin Invest. 1985 Feb; 75(2):746-53. PMID: 3855866.
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      158. Rigby WF, Shen L, Ball ED, Guyre PM, Fanger MW. Differentiation of a human monocytic cell line by 1,25-dihydroxyvitamin D3 (calcitriol): a morphologic, phenotypic, and functional analysis. Blood. 1984 Nov; 64(5):1110-5. PMID: 6548394.
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      159. Ball ED, Guyre PM, Glynn JM, Rigby WF, Fanger MW. Modulation of class I HLA antigens on HL-60 promyelocytic leukemia cells by serum-free medium: re-induction by gamma-IFN and 1,25-dihydroxyvitamin D3 (calcitriol). J Immunol. 1984 May; 132(5):2424-8. PMID: 6425403.
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      160. Ball ED, Guyre PM, Shen L, Glynn JM, Maliszewski CR, Baker PE, Fanger MW. Gamma interferon induces monocytoid differentiation in the HL-60 cell line. J Clin Invest. 1984 Apr; 73(4):1072-7. PMID: 6231309.
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      161. Ball ED, Graziano RF, Pettengill OS, Sorenson GD, Fanger MW. Monoclonal antibodies reactive with small cell carcinoma of the lung. J Natl Cancer Inst. 1984 Mar; 72(3):593-8. PMID: 6321841.
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      162. Ball ED, Bernier GM, Cornwell GG, McIntyre OR, O'Donnell JF, Fanger MW. Monoclonal antibodies to myeloid differentiation antigens: in vivo studies of three patients with acute myelogenous leukemia. Blood. 1983 Dec; 62(6):1203-10. PMID: 6605773.
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      163. Ball ED, Graziano RF, Fanger MW. A unique antigen expressed on myeloid cells and acute leukemia blast cells defined by a monoclonal antibody. J Immunol. 1983 Jun; 130(6):2937-41. PMID: 6574189.
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      164. Graziano RF, Ball ED, Fanger MW. The expression and modulation of human myeloid-specific antigens during differentiation of the HL-60 cell line. Blood. 1983 Jun; 61(6):1215-21. PMID: 6188506.
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      165. Ball ED, Fanger MW. The expression of myeloid-specific antigens on myeloid leukemia cells: correlations with leukemia subclasses and implications for normal myeloid differentiation. Blood. 1983 Mar; 61(3):456-63. PMID: 6186318.
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      166. Ball ED, Fanger MW. The use of myeloid-specific monoclonal antibodies in the diagnosis of leukemia. Diagn Immunol. 1983; 1(2):90-5. PMID: 6209052.
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      167. Ball ED, Graziano RF, Shen L, Fanger MW. Monoclonal antibodies to novel myeloid antigens reveal human neutrophil heterogeneity. Proc Natl Acad Sci U S A. 1982 Sep; 79(17):5374-8. PMID: 6752945.
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      168. Ball ED, Fanger MW. Monoclonal antibodies reactive with human myeloid leukaemia cells. Clin Exp Immunol. 1982 Jun; 48(3):655-65. PMID: 6956470.
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      169. Ball ED, Kadushin JM, Schacter B, Fanger MW. Studies on the ability of monoclonal antibodies to selectively mediate complement-dependent cytotoxicity of human myelogenous leukemia blast cells. J Immunol. 1982 Mar; 128(3):1476-81. PMID: 6948897.
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      170. Myers TJ, Wakem CJ, Ball ED, Tremont SJ. Thrombotic thrombocytopenic purpura: combined treatment with plasmapheresis and antiplatelet agents. Ann Intern Med. 1980 Feb; 92(2 Pt 1):149-55. PMID: 7188723.
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