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Pranav Garimella

Title(s)Assistant Clinical Professor, Medicine
SchoolHealth Sciences
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    Collapse Biography 
    Collapse Education and Training
    Tufts Medical CenterClinical Research Fellowsihp2016Nephrology
    John H. Stroger Jr. Hospital of Cook CountyInternal Medicine Residency2012
    University of MinnesotaMPH/Epidemiology2009School of Public Health
    Jawaharlal Institute of Postgraduate Medical Education & ResearchMBBS2007
    Collapse Awards and Honors
    Gov. of Andhra Pradesh, India2001  - 2005Pratibha Scholarship
    JIPMER, India2007Moh. Hussain Kuthoos Marikayar Endowment Prize in Cardiology
    American Society of Nephrology 2013Ben J. Lipps Research Fellowship (declined)
    American Society of Nephrology 2014Professional Development Seminar Travel Award
    American Society of Nephrology 2014Kidney Week Top Oral Abstracts by Trainee
    American College of Cardiology2016Best Poster and Best Poster by Fellow-In-Training

    Collapse Overview 
    Collapse Overview
    Dr. Pranav Garimella is an Assistant Professor at University of California San Diego School of Medicine. He is an internist and nephrologist with a primary research focus on novel diagnostic and prognostic biomarkers for kidney disease, pharmacokinetics and peripheral artery disease among those with kidney disease. His clinical interests include bone and mineral disorders, kidney stones and autosomal dominant polycystic kidney disease. (ADPKD).

    His research has been funded by the National Institutes of Health, the Center For Aids Research, Veterans Medical Research Foundation and UC San Diego. He is currently the site PI for an RCT evaluating new treatments for ADPKD.

    He mentors medical studies, residents and fellows on research and quality improvement projects in addition to participating in didactics.

    Collapse Research 
    Collapse Research Activities and Funding
    Clinical Applicability of Photoacoustic Ultrasound in Foot Ulcers in Dialysis Patients
    UCSD ACTRI Aug 1, 2019 - Feb 1, 2021
    Role: Principal Investiagator
    Role Description: This project will use photoacoustic ultrasound to create a detailed map of the tissue physiology at the wound site or site of a potential wound. Our overarching hypothesis is that the use of photoacoustic ultrasound will advance our understanding of the pathophysiology of chronic wounds and provide the community a tool to detect ulcers before they are visually apparent.
    Tubular secretion, kidney disease progression, and drug dosing in older adults
    NIH K23DK114556Jul 1, 2018 - Apr 30, 2023
    Role: Principal Investigator
    The role of uromodulin in mediating salt sensitive hypertension
    VMRF Jun 1, 2018 - May 31, 2019
    Role: Principal Investigator
    Tubular Secretion and Kidney Function Change in HIV
    UCSD CFAR CFAR P30 AI036214Jul 1, 2017 - Oct 31, 2018
    Role: Principal Investigator
    Urinary uromodulin and graft failure in kidney transplant recipients
    UCSD Academic Senate RQ279RJun 1, 2017 - Nov 30, 2018
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Websites
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. LaFavers KA, Macedo E, Garimella PS, Lima C, Khan S, Myslinski J, McClintick J, Witzmann FA, Winfree S, Phillips CL, Hato T, Dagher PC, Wu XR, El-Achkar TM, Micanovic R. Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel. Sci Transl Med. 2019 Oct 02; 11(512). PMID: 31578243.
      View in: PubMed
    2. Patidar KR, Garimella PS, Macedo E, Slaven JE, Ghabril MS, Weber RE, Anderson MD, Orman ES, Nephew LD, Desai AP, Chalasani N, El-Achkar TM. Admission Plasma Uromodulin and the Risk of Acute Kidney Injury in Hospitalized Patients with Cirrhosis: a Pilot Study. Am J Physiol Gastrointest Liver Physiol. 2019 Aug 14. PMID: 31411505.
      View in: PubMed
    3. Lee AK, Katz R, Jotwani V, Garimella PS, Ambrosius WT, Cheung AK, Gren LH, Neyra JA, Punzi H, Raphael KL, Shlipak MG, Ix JH. Distinct Dimensions of Kidney Health and Risk of Cardiovascular Disease, Heart Failure, and Mortality. Hypertension. 2019 Aug 05; HYPERTENSIONAHA11913339. PMID: 31378102.
      View in: PubMed
    4. Garimella PS, Lee AK, Ambrosius WT, Bhatt U, Cheung AK, Chonchol M, Craven T, Hawfield AT, Jotwani V, Killeen A, Punzi H, Sarnak MJ, Wall BM, Ix JH, Shlipak MG. Markers of kidney tubule function and risk of cardiovascular disease events and mortality in the SPRINT trial. Eur Heart J. 2019 Jun 30. PMID: 31257404.
      View in: PubMed
    5. Steubl D, Buzkova P, Garimella PS, Ix JH, Devarajan P, Bennett MR, Chaves PHM, Shlipak MG, Bansal N, Sarnak MJ. Association of Serum Uromodulin With ESKD and Kidney Function Decline in the Elderly: The Cardiovascular Health Study. Am J Kidney Dis. 2019 May 22. PMID: 31128770.
      View in: PubMed
    6. Kumar U, Wettersten N, Garimella PS. Cardiorenal Syndrome: Pathophysiology. Cardiol Clin. 2019 Aug; 37(3):251-265. PMID: 31279419.
      View in: PubMed
    7. Bullen AL, Katz R, Lee AK, Anderson CAM, Cheung AK, Garimella PS, Jotwani V, Haley WE, Ishani A, Lash JP, Neyra JA, Punzi H, Rastogi A, Riessen E, Malhotra R, Parikh CR, Rocco MV, Wall BM, Bhatt UY, Shlipak MG, Ix JH, Estrella MM. The SPRINT trial suggests that markers of tubule cell function in the urine associate with risk of subsequent acute kidney injury while injury markers elevate after the injury. Kidney Int. 2019 May 07. PMID: 31262489.
      View in: PubMed
    8. Steubl D, Block M, Herbst V, Nockher WA, Schlumberger W, Kemmner S, Bachmann Q, Angermann S, Wen M, Heemann U, Renders L, Garimella PS, Scherberich J. Urinary uromodulin independently predicts end-stage renal disease and rapid kidney function decline in a cohort of chronic kidney disease patients. Medicine (Baltimore). 2019 May; 98(21):e15808. PMID: 31124979.
      View in: PubMed
    9. Jotwani VK, Lee AK, Estrella MM, Katz R, Garimella PS, Malhotra R, Rifkin DE, Ambrosius W, Freedman BI, Cheung AK, Raphael KL, Drawz P, Neyra JA, Oparil S, Punzi H, Shlipak MG, Ix JH. Urinary Biomarkers of Tubular Damage Are Associated with Mortality but Not Cardiovascular Risk among Systolic Blood Pressure Intervention Trial Participants with Chronic Kidney Disease. Am J Nephrol. 2019; 49(5):346-355. PMID: 30939472.
      View in: PubMed
    10. Steubl D, Buzkova P, Garimella PS, Ix JH, Devarajan P, Bennett MR, Chaves PHM, Shlipak MG, Bansal N, Sarnak MJ. Association of serum uromodulin with mortality and cardiovascular disease in the elderly-the Cardiovascular Health Study. Nephrol Dial Transplant. 2019 Mar 21. PMID: 30903163.
      View in: PubMed
    11. Prasad R, Kamath T, Ginsberg C, Potok OA, Ix JH, Garimella PS, Rifkin DE. The association of the ankle-brachial index, the toe-brachial index, and their difference, with mortality and limb outcomes in dialysis patients. Hemodial Int. 2019 Apr; 23(2):214-222. PMID: 30734987.
      View in: PubMed
    12. Micanovic R, LaFavers K, Garimella PS, Wu XR, El-Achkar TM. Uromodulin (Tamm-Horsfall protein): guardian of urinary and systemic homeostasis. Nephrol Dial Transplant. 2019 Jan 14. PMID: 30649494.
      View in: PubMed
    13. Bostom A, Pasch A, Madsen T, Roberts MB, Franceschini N, Steubl D, Garimella PS, Ix JH, Tuttle KR, Ivanova A, Shireman T, Gohh R, Merhi B, Jarolim P, Kusek JW, Pfeffer MA, Liu S, Eaton CB. Serum Calcification Propensity and Fetuin-A: Biomarkers of Cardiovascular Disease in Kidney Transplant Recipients. Am J Nephrol. 2018; 48(1):21-31. PMID: 29996127.
      View in: PubMed
    14. Chan L, Saha A, Poojary P, Chauhan K, Naik N, Coca S, Garimella PS, Nadkarni GN. National Trends in Emergency Room Visits of Dialysis Patients for Adverse Drug Reactions. Am J Nephrol. 2018; 47(6):441-449. PMID: 29895030.
      View in: PubMed
    15. Bostom A, Steubl D, Garimella PS, Franceschini N, Roberts MB, Pasch A, Ix JH, Tuttle KR, Ivanova A, Shireman T, Kim SJ, Gohh R, Weiner DE, Levey AS, Hsu CY, Kusek JW, Eaton CB. Serum Uromodulin: A Biomarker of Long-Term Kidney Allograft Failure. Am J Nephrol. 2018; 47(4):275-282. PMID: 29698955.
      View in: PubMed
    16. Hsu S, Rifkin DE, Criqui MH, Suder NC, Garimella P, Ginsberg C, Marasco AM, McQuaide BJ, Barinas-Mitchell EJ, Allison MA, Wassel CL, Ix JH. Relationship of femoral artery ultrasound measures of atherosclerosis with chronic kidney disease. J Vasc Surg. 2018 06; 67(6):1855-1863.e1. PMID: 29276107.
      View in: PubMed
    17. Ginsberg C, Katz R, de Boer IH, Kestenbaum BR, Chonchol M, Shlipak MG, Sarnak MJ, Hoofnagle AN, Rifkin DE, Garimella PS, Ix JH. The 24,25 to 25-hydroxyvitamin D ratio and fracture risk in older adults: The cardiovascular health study. Bone. 2018 02; 107:124-130. PMID: 29155243.
      View in: PubMed
    18. Garg PK, Norby FL, Polfus LM, Boerwinkle E, Gibbs RA, Grove ML, Folsom AR, Garimella PS, Matsushita K, Hoogeveen RC, Ballantyne CM. Lipoprotein-associated phospholipase A2 and risk of incident peripheral arterial disease: Findings from The Atherosclerosis Risk in Communities study (ARIC). Atherosclerosis. 2018 01; 268:12-18. PMID: 29169030.
      View in: PubMed
    19. Garimella PS, Balakrishnan P, Correa A, Poojary P, Annapureddy N, Chauhan K, Patel A, Patel S, Konstantinidis I, Chan L, Agarwal SK, Jaar BG, Gidwani U, Matsushita K, Nadkarni GN. Nationwide Trends in Hospital Outcomes and Utilization After Lower Limb Revascularization in Patients on Hemodialysis. JACC Cardiovasc Interv. 2017 10 23; 10(20):2101-2110. PMID: 29050629.
      View in: PubMed
    20. Yang C, Kwak L, Ballew SH, Garimella PS, Jaar BG, Folsom AR, Heiss G, Selvin E, Lutsey PL, Coresh J, Matsushita K. Kidney function, bone-mineral metabolism markers, and future risk of peripheral artery disease. Atherosclerosis. 2017 Dec; 267:167-174. PMID: 28992939.
      View in: PubMed
    21. Nadkarni GN, Chauhan K, Patel A, Saha A, Poojary P, Kamat S, Patel S, Ferrandino R, Konstantinidis I, Garimella PS, Menon MC, Thakar CV. Temporal trends of dialysis requiring acute kidney injury after orthotopic cardiac and liver transplant hospitalizations. BMC Nephrol. 2017 Jul 19; 18(1):244. PMID: 28724404.
      View in: PubMed
    22. Garimella PS, Katz R, Ix JH, Fried LF, Kritchevsky SB, Devarajan P, Bennett MR, Parikh CR, Shlipak MG, Harris TB, Gutiérrez OM, Sarnak MJ. Association of urinary uromodulin with kidney function decline and mortality: the health ABC study?. Clin Nephrol. 2017 Jun; 87(6):278-286. PMID: 28332475.
      View in: PubMed
    23. Malhotra R, Persic V, Zhang W, Brown J, Tao X, Rosales L, Thijssen S, Finkelstein FO, Unruh ML, Ikizler A, Garimella PS, Ix JH, Kooman J, Levin NW, Handelman GJ, Kotanko P. Tryptophan and Kynurenine Levels and Its Association With Sleep, Nonphysical Fatigue, and Depression in Chronic Hemodialysis Patients. J Ren Nutr. 2017 07; 27(4):260-266. PMID: 28366444.
      View in: PubMed
    24. Garimella PS, Li K, Naviaux JC, Shlipak MG, Abdelmalek JA, Castro E, Capparelli EV, Naviaux RK, Ix JH. Utility of Spot Urine Specimens to Assess Tubular Secretion. Am J Kidney Dis. 2017 May; 69(5):709-711. PMID: 28284759.
      View in: PubMed
    25. Garimella PS, Sarnak MJ. Uromodulin in kidney health and disease. Curr Opin Nephrol Hypertens. 2017 03; 26(2):136-142. PMID: 27898524.
      View in: PubMed
    26. Garimella PS, Balakrishnan P, Ammakkanavar NR, Patel S, Patel A, Konstantinidis I, Annapureddy N, Nadkarni GN. Impact of dialysis requirement on outcomes in tumor lysis syndrome. Nephrology (Carlton). 2017 Jan; 22(1):85-88. PMID: 27119419.
      View in: PubMed
    27. Dad T, Garimella PS, Strom JA. Quiz: An Unusual Case of Metabolic Alkalosis in a Patient With CKD. Am J Kidney Dis. 2017 01; 69(1):A13-A16. PMID: 28007194.
      View in: PubMed
    28. Fink HA, Litwack-Harrison S, Taylor BC, Bauer DC, Orwoll ES, Lee CG, Barrett-Connor E, Schousboe JT, Kado DM, Garimella PS, Ensrud KE. Erratum to: Clinical utility of routine laboratory testing to identify possible secondary causes in older men with osteoporosis: the osteoporotic fractures in men (MrOS) study. Osteoporos Int. 2017 01; 28(1):419-420. PMID: 27766366.
      View in: PubMed
    29. Chan L, Mehta S, Chauhan K, Poojary P, Patel S, Pawar S, Patel A, Correa A, Patel S, Garimella PS, Annapureddy N, Agarwal SK, Gidwani U, Coca SG, Nadkarni GN. National Trends and Impact of Acute Kidney Injury Requiring Hemodialysis in Hospitalizations With Atrial Fibrillation. J Am Heart Assoc. 2016 12 20; 5(12). PMID: 27998917.
      View in: PubMed
    30. Nowak KL, Bartz TM, Dalrymple L, de Boer IH, Kestenbaum B, Shlipak MG, Garimella PS, Ix JH, Chonchol M. Fibroblast Growth Factor 23 and the Risk of Infection-Related Hospitalization in Older Adults. J Am Soc Nephrol. 2017 Apr; 28(4):1239-1246. PMID: 28122946.
      View in: PubMed
    31. Garimella PS, Bartz TM, Ix JH, Chonchol M, Shlipak MG, Devarajan P, Bennett MR, Sarnak MJ. Urinary Uromodulin and Risk of Urinary Tract Infections: The Cardiovascular Health Study. Am J Kidney Dis. 2017 Jun; 69(6):744-751. PMID: 28029393.
      View in: PubMed
    32. Garimella PS, Jaber BL, Tighiouart H, Liangos O, Bennett MR, Devarajan P, El-Achkar TM, Sarnak MJ. Association of Preoperative Urinary Uromodulin with AKI after Cardiac Surgery. Clin J Am Soc Nephrol. 2017 01 06; 12(1):10-18. PMID: 27797887.
      View in: PubMed
    33. Garimella PS, Wang W, Lin SF, Hymes J, Lacson E. Incident diabetic foot ulcers and mortality in hemodialysis patients. Hemodial Int. 2017 01; 21(1):145-147. PMID: 27624300.
      View in: PubMed
    34. Barzilay JI, Bužková P, Fink HA, Cauley JA, Robbins JA, Garimella PS, Jalal DI, Mukamal KJ. Systemic markers of microvascular disease and bone mineral density in older adults : The cardiovascular health study. Osteoporos Int. 2016 11; 27(11):3217-3225. PMID: 27250972.
      View in: PubMed
    35. Chen J, Mohler ER, Garimella PS, Hamm LL, Xie D, Kimmel S, Townsend RR, Budoff M, Pan Q, Nessel L, Steigerwalt S, Wright JT, He J. Ankle Brachial Index and Subsequent Cardiovascular Disease Risk in Patients With Chronic Kidney Disease. J Am Heart Assoc. 2016 05 31; 5(6). PMID: 27247339.
      View in: PubMed
    36. Garimella PS, Jaber BL. Patiromer for Hyperkalemia in Diabetic CKD: A New Kid on the Block. Am J Kidney Dis. 2016 Apr; 67(4):545-7. PMID: 26806002.
      View in: PubMed
    37. Garimella PS, Katz R, Patel KV, Kritchevsky SB, Parikh CR, Ix JH, Fried LF, Newman AB, Shlipak MG, Harris TB, Sarnak MJ. Association of Serum Erythropoietin With Cardiovascular Events, Kidney Function Decline, and Mortality: The Health Aging and Body Composition Study. Circ Heart Fail. 2016 Jan; 9(1):e002124. PMID: 26721912.
      View in: PubMed
    38. Fink HA, Litwack-Harrison S, Taylor BC, Bauer DC, Orwoll ES, Lee CG, Barrett-Connor E, Schousboe JT, Kado DM, Garimella PS, Ensrud KE. Clinical utility of routine laboratory testing to identify possible secondary causes in older men with osteoporosis: the Osteoporotic Fractures in Men (MrOS) Study. Osteoporos Int. 2016 Jan; 27(1):331-8. PMID: 26458388.
      View in: PubMed
    39. Garimella PS, Biggs ML, Katz R, Ix JH, Bennett MR, Devarajan P, Kestenbaum BR, Siscovick DS, Jensen MK, Shlipak MG, Chaves PH, Sarnak MJ. Urinary uromodulin, kidney function, and cardiovascular disease in elderly adults. Kidney Int. 2015 Nov; 88(5):1126-34. PMID: 26154925.
      View in: PubMed
    40. Fink HA, Bužková P, Garimella PS, Mukamal KJ, Cauley JA, Kizer JR, Barzilay JI, Jalal DI, Ix JH. Association of Fetuin-A With Incident Fractures in Community-Dwelling Older Adults: The Cardiovascular Health Study. J Bone Miner Res. 2015 Aug; 30(8):1394-402. PMID: 25656814.
      View in: PubMed
    41. Garimella PS, Rennke HG, Strom JA. Alendronate associated focal segmental glomerulosclerosis: a case report and review of the literature. CEN Case Rep. 2015 Apr 01; 4(1):20-23. PMID: 26101727.
      View in: PubMed
    42. Ix JH, Biggs ML, Mukamal K, Djousse L, Siscovick D, Tracy R, Katz R, Delaney JA, Chaves P, Rifkin DE, Hughes-Austin JM, Garimella PS, Sarnak MJ, Shlipak MG, Kizer JR. Urine Collagen Fragments and CKD Progression-The Cardiovascular Health Study. J Am Soc Nephrol. 2015 Oct; 26(10):2494-503. PMID: 25655067.
      View in: PubMed
    43. Garimella PS, Hirsch AT. Peripheral artery disease and chronic kidney disease: clinical synergy to improve outcomes. Adv Chronic Kidney Dis. 2014 Nov; 21(6):460-71. PMID: 25443571.
      View in: PubMed
    44. Garimella PS, Ix JH, Katz R, Shlipak MG, Criqui MH, Siscovick DS, Kramer H, Sibley CT, Sarnak MJ. Association of albumin-creatinine ratio and cystatin C with change in ankle-brachial index: the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Kidney Dis. 2015 Jan; 65(1):33-40. PMID: 24998036.
      View in: PubMed
    45. Garimella PS, Ix JH, Katz R, Chonchol MB, Kestenbaum BR, de Boer IH, Siscovick DS, Shastri S, Hiramoto JS, Shlipak MG, Sarnak MJ. Fibroblast growth factor 23, the ankle-brachial index, and incident peripheral artery disease in the Cardiovascular Health Study. Atherosclerosis. 2014 Mar; 233(1):91-6. PMID: 24529128.
      View in: PubMed
    46. Garimella PS, Uhlig K. Current issues in the management and monitoring of hypertension in chronic kidney disease. Curr Opin Nephrol Hypertens. 2013 Nov; 22(6):599-606. PMID: 24076554.
      View in: PubMed
    47. Cohen-Bucay A, Garimella P, Ezeokonkwo C, Bijol V, Strom JA, Jaber BL. Acute oxalate nephropathy associated with Clostridium difficile colitis. Am J Kidney Dis. 2014 Jan; 63(1):113-8. PMID: 24183111.
      View in: PubMed
    48. Fink HA, Wilt TJ, Eidman KE, Garimella PS, MacDonald R, Rutks IR, Brasure M, Kane RL, Ouellette J, Monga M. Medical management to prevent recurrent nephrolithiasis in adults: a systematic review for an American College of Physicians Clinical Guideline. Ann Intern Med. 2013 Apr 02; 158(7):535-43. PMID: 23546565.
      View in: PubMed
    49. Garimella PS, Sarnak MJ. Cardiovascular disease in CKD in 2012: moving forward, slowly but surely. Nat Rev Nephrol. 2013 Feb; 9(2):69-70. PMID: 23296300.
      View in: PubMed
    50. Garimella PS, Paudel ML, Ensrud KE, Marshall LM, Taylor BC, Fink HA. Association between body size and composition and erectile dysfunction in older men: Osteoporotic Fractures in Men Study. J Am Geriatr Soc. 2013 Jan; 61(1):46-54. PMID: 23311552.
      View in: PubMed
    51. Gosain P, Garimella PS, Hart PD, Agarwal R. Renal sympathetic denervation for treatment of resistant hypertension: a systematic review. J Clin Hypertens (Greenwich). 2013 Jan; 15(1):75-84. PMID: 23282128.
      View in: PubMed
    52. Garimella PS, Agarwal R, Katz A. The utility of repeat enzyme immunoassay testing for the diagnosis of Clostridium difficile infection: a systematic review of the literature. J Postgrad Med. 2012 Jul-Sep; 58(3):194-8. PMID: 23023352.
      View in: PubMed
    53. Garimella PS, Hart PD, O'Hare A, DeLoach S, Herzog CA, Hirsch AT. Peripheral artery disease and CKD: a focus on peripheral artery disease as a critical component of CKD care. Am J Kidney Dis. 2012 Oct; 60(4):641-54. PMID: 22560831.
      View in: PubMed
    54. Garimella PS, Fink HA, Macdonald R, Wilt TJ. Naftopidil for the treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia. Cochrane Database Syst Rev. 2009 Oct 07; (4):CD007360. PMID: 19821408.
      View in: PubMed
    55. Agrawal V, Garimella PS, Roshan SJ, Ghosh AK. Questionnaire survey of physicians: Design and practical use in nephrology. Indian J Nephrol. 2009 Apr; 19(2):41-7. PMID: 20368922.
      View in: PubMed
    56. Fink HA, Akornor JW, Garimella PS, MacDonald R, Cutting A, Rutks IR, Monga M, Wilt TJ. Diet, fluid, or supplements for secondary prevention of nephrolithiasis: a systematic review and meta-analysis of randomized trials. Eur Urol. 2009 Jul; 56(1):72-80. PMID: 19321253.
      View in: PubMed