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Francis Gabbai

TitleSenate Emeritus
InstitutionUniversity of California San Diego
DepartmentMedicine
Address9500 Gilman Drive #9111H
La Jolla CA 92093
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    AASK Cohort Study, Clinical Center #0-UCSD
    NIH/NIDDK U01DK048645Aug 15, 1996 - Jun 30, 2008
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Drawz PE, Brown R, De Nicola L, Fujii N, Gabbai F, Gassman J, He J, Iimuro S, Lash J, Minutolo R, Phillips RA, Rudser K, Ruilope L, Steigerwalt S, Townsend RR, Xie D, Rahman M. Variations in 24-Hour BP Profiles in Cohorts of Patients with Kidney Disease around the World: The I-DARE Study. Clin J Am Soc Nephrol. 2018 Jul 05. PMID: 29976600.
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    2. Minutolo R, Gabbai F, Provenzano M, Chiodini P, Borrelli S, Garofalo C, Sasso FC, Santoro D, Bellizzi V, Conte G, De Nicola L. Cardiorenal prognosis by residual proteinuria level in diabetic chronic kidney disease: pooled analysis of four cohort studies. Nephrol Dial Transplant. 2018 Mar 02. PMID: 29509925.
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    3. Gabbai F. The role of renal response to amino acid infusion and oral protein load in normal kidneys and kidney with acute and chronic disease. Curr Opin Nephrol Hypertens. 2018 01; 27(1):23-29. PMID: 29068795.
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    4. Ix JH, Katz R, Bansal N, Foster M, Weiner DE, Tracy R, Jotwani V, Hughes-Austin J, McKay D, Gabbai F, Hsu CY, Bostom A, Levey AS, Shlipak MG. Urine Fibrosis Markers and Risk of Allograft Failure in Kidney Transplant Recipients: A Case-Cohort Ancillary Study of the FAVORIT Trial. Am J Kidney Dis. 2017 Mar; 69(3):410-419. PMID: 28024930.
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    5. Paoletti E, De Nicola L, Gabbai F, Chiodini P, Ravera M, Pieracci L, Marre S, Cassottana P, Lucà S, Vettoretti S, Borrelli S, Conte G, Minutolo R. Associations of Left Ventricular Hypertrophy and Geometry with Adverse Outcomes in Patients with CKD and Hypertension. Clin J Am Soc Nephrol. 2016 Feb 05; 11(2):271-9. PMID: 26668021; PMCID: PMC4741044 [Available on 02/05/17].
    6. Minutolo R, Gabbai F, Chiodini P, Garofalo C, Stanzione G, Liberti ME, Pacilio M, Borrelli S, Provenzano M, Conte G, De Nicola L. Reassessment of Ambulatory Blood Pressure Improves Renal Risk Stratification in Nondialysis Chronic Kidney Disease: Long-Term Cohort Study. Hypertension. 2015 Sep; 66(3):557-62. PMID: 26150434.
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    7. Minutolo R, Gabbai F, Agarwal R, Chiodini P, Borrelli S, Bellizzi V, Nappi F, Stanzione G, Conte G, De Nicola L. Assessment of achieved clinic and ambulatory blood pressure recordings and outcomes during treatment in hypertensive patients with CKD: a multicenter prospective cohort study. Am J Kidney Dis. 2014 Nov; 64(5):744-52. PMID: 25082100.
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    8. De Nicola L, Gabbai F, Liberti ME, Sagliocca A, Conte G, Minutolo R. Sodium/glucose cotransporter 2 inhibitors and prevention of diabetic nephropathy: targeting the renal tubule in diabetes. Am J Kidney Dis. 2014 Jul; 64(1):16-24. PMID: 24673844.
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    9. De Nicola L, Gabbai F, Agarwal R, Chiodini P, Borrelli S, Bellizzi V, Nappi F, Conte G, Minutolo R. Prevalence and prognostic role of resistant hypertension in chronic kidney disease patients. J Am Coll Cardiol. 2013 Jun 18; 61(24):2461-2467. PMID: 23623908.
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    10. Rahman M, Greene T, Phillips RA, Agodoa LY, Bakris GL, Charleston J, Contreras G, Gabbai F, Hiremath L, Jamerson K, Kendrick C, Kusek JW, Lash JP, Lea J, Miller ER, Rostand S, Toto R, Wang X, Wright JT, Appel LJ. A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease. Hypertension. 2013 Jan; 61(1):82-8. PMID: 23172931; PMCID: PMC3523681.
    11. Gabbai F, Rahman M, Hu B, Appel LJ, Charleston J, Contreras G, Faulkner ML, Hiremath L, Jamerson KA, Lea JP, Lipkowitz MS, Pogue VA, Rostand SG, Smogorzewski MJ, Wright JT, Greene T, Gassman J, Wang X, Phillips RA. Relationship between ambulatory BP and clinical outcomes in patients with hypertensive CKD. Clin J Am Soc Nephrol. 2012 Nov; 7(11):1770-6. PMID: 22935847; PMCID: PMC3488952.
    12. Singh P, Blantz RC, Rosenberger C, Gabbai F, Schoeb TR, Thomson SC. Aberrant tubuloglomerular feedback and HIF-1a confer resistance to ischemia after subtotal nephrectomy. J Am Soc Nephrol. 2012 Mar; 23(3):483-93. PMID: 22266667; PMCID: PMC3294306.
    13. De Nicola L, Borrelli S, Chiodini P, Zamboli P, Iodice C, Gabbai F, Conte G, Minutolo R. Hypertension management in chronic kidney disease: translating guidelines into daily practice. J Nephrol. 2011 Nov-Dec; 24(6):733-41. PMID: 21319133.
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    14. Minutolo R, Agarwal R, Borrelli S, Chiodini P, Bellizzi V, Nappi F, Cianciaruso B, Zamboli P, Conte G, Gabbai F, De Nicola L. Prognostic role of ambulatory blood pressure measurement in patients with nondialysis chronic kidney disease. Arch Intern Med. 2011 Jun 27; 171(12):1090-8. PMID: 21709109.
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    15. De Nicola L, Borrelli S, Gabbai F, Chiodini P, Zamboli P, Iodice C, Vitiello S, Conte G, Minutolo R. Burden of resistant hypertension in hypertensive patients with non-dialysis chronic kidney disease. Kidney Blood Press Res. 2011; 34(1):58-67. PMID: 21212686.
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    16. Appel LJ, Wright JT, Greene T, Agodoa LY, Astor BC, Bakris GL, Cleveland WH, Charleston J, Contreras G, Faulkner ML, Gabbai F, Gassman JJ, Hebert LA, Jamerson KA, Kopple JD, Kusek JW, Lash JP, Lea JP, Lewis JB, Lipkowitz MS, Massry SG, Miller ER, Norris K, Phillips RA, Pogue VA, Randall OS, Rostand SG, Smogorzewski MJ, Toto RD, Wang X. Intensive blood-pressure control in hypertensive chronic kidney disease. N Engl J Med. 2010 Sep 02; 363(10):918-29. PMID: 20818902; PMCID: PMC3662974.
    17. Appel LJ, Wright JT, Greene T, Kusek JW, Lewis JB, Wang X, Lipkowitz MS, Norris KC, Bakris GL, Rahman M, Contreras G, Rostand SG, Kopple JD, Gabbai F, Schulman GI, Gassman JJ, Charleston J, Agodoa LY. Long-term effects of renin-angiotensin system-blocking therapy and a low blood pressure goal on progression of hypertensive chronic kidney disease in African Americans. Arch Intern Med. 2008 Apr 28; 168(8):832-9. PMID: 18443258; PMCID: PMC3870204.
    18. Ruiz M, Singh P, Thomson SC, Munger K, Blantz RC, Gabbai F. L-arginine-induced glomerular hyperfiltration response: the roles of insulin and ANG II. Am J Physiol Regul Integr Comp Physiol. 2008 May; 294(5):R1744-51. PMID: 18353876.
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    19. Satriano J, Cunard R, Peterson OW, Dousa T, Gabbai F, Blantz RC. Effects on kidney filtration rate by agmatine requires activation of ryanodine channels for nitric oxide generation. Am J Physiol Renal Physiol. 2008 Apr; 294(4):F795-800. PMID: 18199604.
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    20. Minutolo R, Gabbai F, Borrelli S, Scigliano R, Trucillo P, Baldanza D, Laurino S, Mascia S, Conte G, De Nicola L. Changing the timing of antihypertensive therapy to reduce nocturnal blood pressure in CKD: an 8-week uncontrolled trial. Am J Kidney Dis. 2007 Dec; 50(6):908-17. PMID: 18037091.
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    21. Deng A, Miracle CM, Lortie M, Satriano J, Gabbai F, Munger KA, Thomson SC, Blantz RC. Kidney oxygen consumption, carbonic anhydrase, and proton secretion. Am J Physiol Renal Physiol. 2006 May; 290(5):F1009-15. PMID: 16352743.
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    22. Lortie MJ, Satriano J, Gabbai F, Thareau S, Khang S, Deng A, Pizzo DP, Thomson SC, Blantz RC, Munger KA. Production of arginine by the kidney is impaired in a model of sepsis: early events following LPS. Am J Physiol Regul Integr Comp Physiol. 2004 Dec; 287(6):R1434-40. PMID: 15308488.
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    23. Slomowitz LA, Gabbai F, Khang SJ, Satriano J, Thareau S, Deng A, Thomson SC, Blantz RC, Munger KA. Protein intake regulates the vasodilatory function of the kidney and NMDA receptor expression. Am J Physiol Regul Integr Comp Physiol. 2004 Nov; 287(5):R1184-9. PMID: 15242825.
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    24. Thomson SC, Deng A, Komine N, Hammes JS, Blantz RC, Gabbai F. Early diabetes as a model for testing the regulation of juxtaglomerular NOS I. Am J Physiol Renal Physiol. 2004 Oct; 287(4):F732-8. PMID: 15213066.
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    25. Narsipur SS, Peterson OW, Smith R, Bigby TD, Parthasarathy S, Gabbai F, Wilson CB, Blantz RC. Mechanisms of glomerular immune injury: effects of antioxidant treatment. J Am Soc Nephrol. 2003 Jul; 14(7):1748-55. PMID: 12819234.
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    26. Mehta RL, McDonald B, Gabbai F, Pahl M, Farkas A, Pascual MT, Zhuang S, Kaplan RM, Chertow GM. Nephrology consultation in acute renal failure: does timing matter? Am J Med. 2002 Oct 15; 113(6):456-61. PMID: 12427493.
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    27. Slomowitz LA, Deng A, Hammes JS, Gabbai F, Thomson SC. Glomerulotubular balance, dietary protein, and the renal response to glycine in diabetic rats. Am J Physiol Regul Integr Comp Physiol. 2002 Apr; 282(4):R1096-103. PMID: 11893614.
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    28. Blantz RC, Deng A, Lortie M, Munger K, Vallon V, Gabbai F, Thomson SC. The complex role of nitric oxide in the regulation of glomerular ultrafiltration. Kidney Int. 2002 Mar; 61(3):782-5. PMID: 11849425.
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    29. Gabbai F, Hammond TC, Thomson SC, Khang S, Kelly CJ. Effect of acute iNOS inhibition on glomerular function in tubulointerstitial nephritis. Kidney Int. 2002 Mar; 61(3):851-4. PMID: 11849437.
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    30. Komine N, Khang S, Wead LM, Blantz RC, Gabbai F. Effect of combining an ACE inhibitor and an angiotensin II receptor blocker on plasma and kidney tissue angiotensin II levels. Am J Kidney Dis. 2002 Jan; 39(1):159-64. PMID: 11774115.
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    31. Mehta RL, McDonald B, Gabbai F, Pahl M, Pascual MT, Farkas A, Kaplan RM. A randomized clinical trial of continuous versus intermittent dialysis for acute renal failure. Kidney Int. 2001 Sep; 60(3):1154-63. PMID: 11532112.
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    32. O'Connor DT, Tyrell EA, Kailasam MT, Miller LM, Martinez JA, Henry RR, Parmer RJ, Gabbai F. Early alteration in glomerular reserve in humans at genetic risk of essential hypertension: mechanisms and consequences. Hypertension. 2001 Mar; 37(3):898-906. PMID: 11244015.
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    33. Gabbai F. Effects of nitric oxide synthase blockers on renal function. Nephrol Dial Transplant. 2001; 16 Suppl 1:10-3. PMID: 11369813.
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    34. Ishizuka S, Cunard R, Poucell-Hatton S, Wead L, Lortie M, Thomson SC, Gabbai F, Satriano J, Blantz RC. Agmatine inhibits cell proliferation and improves renal function in anti-thy-1 glomerulonephritis. J Am Soc Nephrol. 2000 Dec; 11(12):2256-64. PMID: 11095648.
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    35. Feng L, Garcia GE, Yang Y, Xia Y, Gabbai F, Peterson OW, Abraham JA, Blantz RC, Wilson CB. Heparin-binding EGF-like growth factor contributes to reduced glomerular filtration rate during glomerulonephritis in rats. J Clin Invest. 2000 Feb; 105(3):341-50. PMID: 10675360; PMCID: PMC377436.
    36. Gabbai F, Blantz RC. Role of nitric oxide in renal hemodynamics. Semin Nephrol. 1999 May; 19(3):242-50. PMID: 10226330.
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    37. Gabbai F, Boggiano C, Peter T, Khang S, Archer C, Gold DP, Kelly CJ. Inhibition of inducible nitric oxide synthase intensifies injury and functional deterioration in autoimmune interstitial nephritis. J Immunol. 1997 Dec 15; 159(12):6266-75. PMID: 9550431.
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    38. Garcia GE, Brown MR, Wead LM, Braun S, Gabbai F. Effect of reduction of nitric oxide on plasma and kidney tissue angiotensin II levels. Am J Hypertens. 1997 Oct; 10(10 Pt 1):1103-8. PMID: 9370380.
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    39. Gabbai F, Peterson OW, Khang S. [Glomerular hemodynamics in the isolated and perfused kidney. Effect of the inhibition of nitric oxide synthase]. Gac Med Mex. 1997 Jul-Aug; 133(4):307-13. PMID: 9410792.
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    40. Gabbai F, De Nicola L, Peterson OW, Obagi S, Thomson SC, Tucker BJ, Keiser JA, Wilson CB, Blantz RC. Renal response to blood pressure elevation in normal and glomerulonephritic rats. J Am Soc Nephrol. 1996 Dec; 7(12):2590-9. PMID: 8989737.
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    41. Garcia GE, Hammond TC, Wead LM, Mendonca MM, Brown MR, Gabbai F. Effect of angiotensin II on the renal response to amino acid in rats. Am J Kidney Dis. 1996 Jul; 28(1):115-23. PMID: 8712205.
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    42. Blantz RC, Lortie M, Vallon V, Gabbai F, Parmer RJ, Thomson S. Activities of nitric oxide in normal physiology and uremia. Semin Nephrol. 1996 May; 16(3):144-50. PMID: 8734457.
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    43. Vallon V, Peterson OW, Gabbai F, Blantz RC, Thomson SC. Interactive control of renal function by alpha 2-adrenergic system and nitric oxide: role of angiotensin II. J Cardiovasc Pharmacol. 1995 Dec; 26(6):916-22. PMID: 8606528.
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    44. Gabbai F, De Nicola L, Garcia GE, Blantz RC. Role of angiotensin in the regulation of renal response to proteins. Semin Nephrol. 1995 Sep; 15(5):396-404. PMID: 8525141.
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    45. Gabbai F. Renal reserve in patients with high blood pressure. Semin Nephrol. 1995 Sep; 15(5):482-7. PMID: 8525152.
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    46. Gabbai F, Thomson SC, Peterson O, Wead L, Malvey K, Blantz RC. Glomerular and tubular interactions between renal adrenergic activity and nitric oxide. Am J Physiol. 1995 Jun; 268(6 Pt 2):F1004-8. PMID: 7611442.
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    47. Gabbai F, Garcia GE, Blantz RC, De Nicola L. Role of nitric oxide in glomerular physiology and pathophysiology. Adv Nephrol Necker Hosp. 1995; 24:3-18. PMID: 7572414.
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    48. Gabbai F, Peterson OW, Khang S, Wilson CB, Blantz RC. Glomerular hemodynamics in cell-free and erythrocyte-perfused isolated rat kidney. Am J Physiol. 1994 Sep; 267(3 Pt 2):F423-7. PMID: 8092255.
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    49. Blantz RC, Gabbai F, Peterson O, Wilson CB, Kihara I, Kawachi H, Shimizu F, Yamamoto T. Water and protein permeability is regulated by the glomerular epithelial slit diaphragm. J Am Soc Nephrol. 1994 Jun; 4(12):1957-64. PMID: 7919149.
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    50. Garcia GE, Gabbai F, O'Connor DT, Dinh TQ, Kennedy B, Ziegler MG, Takiyyuddin MA. Does chromostatin influence catecholamine release or blood pressure in vivo? Peptides. 1994 Jan; 15(1):195-7. PMID: 8015978.
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    51. Gabbai F, Peterson OW, Blantz RC. Glycine prevents toxic tubular cell injury. Ren Fail. 1994; 16(1):101-8. PMID: 8184136.
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    52. De Nicola L, Peterson OW, Obagi S, Kaiser JA, Wilson CB, Gabbai F. Renal functional reserve in experimental chronic glomerulonephritis. Nephrol Dial Transplant. 1994; 9(10):1383-9. PMID: 7816249.
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    53. De Nicola L, Thomson SC, Wead LM, Brown MR, Gabbai F. Arginine feeding modifies cyclosporine nephrotoxicity in rats. J Clin Invest. 1993 Oct; 92(4):1859-65. PMID: 8408638; PMCID: PMC288350.
    54. Takiyyuddin MA, De Nicola L, Gabbai F, Dinh TQ, Kennedy B, Ziegler MG, Sabban EL, Parmer RJ, O'Connor DT. Catecholamine secretory vesicles. Augmented chromogranins and amines in secondary hypertension. Hypertension. 1993 May; 21(5):674-9. PMID: 8491501.
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    55. Blantz RC, Gabbai F, Tucker BJ, Yamamoto T, Wilson CB. Role of mesangial cell in glomerular response to volume and angiotensin II. Am J Physiol. 1993 Jan; 264(1 Pt 2):F158-65. PMID: 8430826.
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    56. Thomson SC, Gabbai F, Tucker BJ, Blantz RC. Interaction between alpha 2-adrenergic and angiotensin II systems in the control of glomerular hemodynamics as assessed by renal micropuncture in the rat. J Clin Invest. 1992 Aug; 90(2):604-11. PMID: 1353766; PMCID: PMC443139.
    57. De Nicola L, Keiser JA, Blantz RC, Gabbai F. Angiotensin II and renal functional reserve in rats with Goldblatt hypertension. Hypertension. 1992 Jun; 19(6 Pt 2):790-4. PMID: 1592482.
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    58. De Nicola L, Blantz RC, Gabbai F. Nitric oxide and angiotensin II. Glomerular and tubular interaction in the rat. J Clin Invest. 1992 Apr; 89(4):1248-56. PMID: 1556186; PMCID: PMC442985.
    59. De Nicola L, Blantz RC, Gabbai F. Renal functional reserve in the early stage of experimental diabetes. Diabetes. 1992 Mar; 41(3):267-73. PMID: 1551487.
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    60. De Nicola L, Gabbai F, Feng L, Tang WW, Wilson CB, Blantz RC. Inflammatory mediators in glomerular injury. Ren Fail. 1992; 14(3):401-5. PMID: 1509173.
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    61. De Nicola L, Blantz RC, Gabbai F. Renal functional reserve in treated and untreated hypertensive rats. Kidney Int. 1991 Sep; 40(3):406-12. PMID: 1787641.
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    62. Blantz RC, Gabbai F, Peterson OW, Thomson SC. Tubuloglomerular feedback activity after acute reductions in renal mass. Kidney Int Suppl. 1991 Jun; 32:S102-5. PMID: 1881030.
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    63. Gabbai F, Wilson CB, Blantz RC. Glomerular hemodynamic consequences of immune injury. Semin Nephrol. 1991 May; 11(3):367-72. PMID: 2057650.
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    64. Blantz RC, Gabbai F, Thomson SC, Tucker BJ. Adrenergic influences and interactions with angiotensin II. Kidney Int Suppl. 1990 Nov; 30:S84-6. PMID: 2259084.
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    65. Tapia E, Gabbai F, Calleja C, Franco M, Cermeño JL, Bobadilla NA, Pérez JM, Alvarado JA, Herrera-Acosta J. Determinants of renal damage in rats with systemic hypertension and partial renal ablation. Kidney Int. 1990 Oct; 38(4):642-8. PMID: 2232504.
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    66. Blantz RC, Thomson SC, Peterson OW, Gabbai F. Physiologic adaptations of the tubuloglomerular feedback system. Kidney Int. 1990 Oct; 38(4):577-83. PMID: 2232499.
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    67. Thomson SC, Tucker BJ, Gabbai F, Blantz RC. Glomerular hemodynamics and alpha 2-adrenoreceptor stimulation: the role of renal nerves. Am J Physiol. 1990 Jan; 258(1 Pt 2):F21-7. PMID: 1967910.
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    68. Peterson OW, Gabbai F, Myers RR, Mizisin AP, Blantz RC. A single nephron model of acute tubular injury: role of tubuloglomerular feedback. Kidney Int. 1989 Dec; 36(6):1037-44. PMID: 2601254.
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    69. Blantz RC, Gabbai F. Glomerular hemodynamics in pathophysiologic conditions. Am J Hypertens. 1989 Nov; 2(11 Pt 2):208S-212S. PMID: 2684227.
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    70. Gabbai F, Peterson OW, Prost JF, Blantz RC. Effect of tertatolol on glomerular hemodynamics in the normal Munich-Wistar rat. Am J Hypertens. 1989 Nov; 2(11 Pt 2):213S-218S. PMID: 2573366.
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    71. Gabbai F, Mundy CA, Wilson CB, Blantz RC. An evaluation of the role of complement depletion in experimental membranous nephropathy in the rat. Lab Invest. 1988 May; 58(5):539-48. PMID: 3367636.
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    72. Gabbai F, Wilson CB, Blantz RC. Role of angiotensin II in experimental membranous nephropathy. Am J Physiol. 1988 Apr; 254(4 Pt 2):F500-6. PMID: 2833120.
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    73. Herrera-Acosta J, Tapia E, Bobadilla NA, Romero L, Cermeño JL, Alvarado JA, Gabbai F. Evaluating hyperfiltration with glycine in hypertensive rats with renal ablation. Hypertension. 1988 Feb; 11(2 Pt 2):I33-7. PMID: 3346063.
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    74. Blantz RC, Gabbai F, Wilson CB. Glomerular hemodynamics in experimental glomerulonephritis. Adv Nephrol Necker Hosp. 1988; 17:3-13. PMID: 3124544.
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    75. Gabbai F, Gushwa LC, Wilson CB, Blantz RC. An evaluation of the development of experimental membranous nephropathy. Kidney Int. 1987 Jun; 31(6):1267-78. PMID: 3613404.
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    76. Blantz RC, Gabbai F. Effect of angiotensin II on glomerular hemodynamics and ultrafiltration coefficient. Kidney Int Suppl. 1987 May; 20:S108-11. PMID: 3298797.
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    77. Gabbai F, Gushwa LC, Peterson OW, Wilson CB, Blantz RC. Analysis of renal function in the two-kidney Goldblatt model. Am J Physiol. 1987 Jan; 252(1 Pt 2):F131-7. PMID: 3812698.
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    78. Gabbai F, Tapia E, Cermeño JL, Romero L, Bobadilla NA, Alvarado JA, Herrera-Acosta H. Evaluation of renal functional reserve of contralateral kidney of two-kidney, one clip Goldblatt hypertensive rats. J Hypertens Suppl. 1986 Dec; 4(5):S279-81. PMID: 15362235.
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