Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Joseph Pogliano

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentMolecular Biology
    Address9500 Gilman Drive #0377
    CA La Jolla 92093
    Phone858-822-4074
    vCardDownload vCard

      Collapse Research 
      Collapse Research Activities and Funding
      Targeted discovery of antibiotics from cave bacteria
      NIH R01AI117712Mar 1, 2016 - Feb 28, 2020
      Role: Principal Investigator
      Identification of natural products targeting new pathways in bacteria
      NIH R01AI113295May 12, 2014 - Apr 30, 2019
      Role: Principal Investigator
      Characterization of a bacteriophage tubulin involved in viral replication
      NIH R01GM104556Aug 1, 2013 - Apr 30, 2017
      Role: Principal Investigator
      Circadian gating of cell division by the cyanobacterial oscillator
      NIH R01GM100116Aug 1, 2012 - Jul 31, 2016
      Role: Principal Investigator
      Cytology and function of ParA in E. coli
      NIH R01GM084334Sep 30, 2009 - Aug 31, 2011
      Role: Principal Investigator
      DNA segregation during Bacillus growth and development
      NIH R01GM073898Aug 1, 2006 - Jul 31, 2014
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Sakoulas G, Rose W, Berti A, Olson J, Mungia J, Nonejuie P, Sakoulas E, Rybak MJ, Pogliano J, Nizet V. Classical ß-lactamase Inhibitors Potentiate the Activity of Daptomycin against Methicillin-Resistant Staphylococcus aureus and Colistin Against Acinetobacter baumannii. Antimicrob Agents Chemother. 2016 Nov 21. PMID: 27872080.
        View in: PubMed
      2. Sakoulas G, Olson J, Yim J, Singh NB, Kumaraswamy M, Quach DT, Rybak MJ, Pogliano J, Nizet V. Cefazolin and Ertapenem: A Synergistic Combination Used to Clear Persistent Staphylococcus aureus Bacteremia. Antimicrob Agents Chemother. 2016 Aug 29. PMID: 27572414.
        View in: PubMed
      3. Berti AD, Theisen E, Sauer JD, Nonejuie P, Olson J, Pogliano J, Sakoulas G, Nizet V, Proctor RA, Rose WE. Penicillin Binding Protein 1 Is Important in the Compensatory Response of Staphylococcus aureus to Daptomycin-Induced Membrane Damage and Is a Potential Target for ß-Lactam-Daptomycin Synergy. Antimicrob Agents Chemother. 2015; 60(1):451-8. PMID: 26525797.
        View in: PubMed
      4. Sakoulas G, Kumaraswamy M, Nonejuie P, Werth BJ, Rybak MJ, Pogliano J, Rice LB, Nizet V. Differential Effects of Penicillin Binding Protein Deletion on the Susceptibility of Enterococcus faecium to Cationic Peptide Antibiotics. Antimicrob Agents Chemother. 2015 Oct; 59(10):6132-9. PMID: 26195528.
        View in: PubMed
      5. Hindler JA, Wong-Beringer A, Charlton CL, Miller SA, Kelesidis T, Carvalho M, Sakoulas G, Nonejuie P, Pogliano J, Nizet V, Humphries R. In Vitro Activity of Daptomycin in Combination with ß-Lactams, Gentamicin, Rifampin, and Tigecycline against Daptomycin-Nonsusceptible Enterococci. Antimicrob Agents Chemother. 2015 Jul; 59(7):4279-88. PMID: 25963982.
        View in: PubMed
      6. Sakoulas G, Nonejuie P, Kullar R, Pogliano J, Rybak MJ, Nizet V. Examining the Use of Ceftaroline in the Treatment of Streptococcus pneumoniae Meningitis with Reference to Human Cathelicidin LL-37. Antimicrob Agents Chemother. 2015 Apr; 59(4):2428-31. PMID: 25605351.
        View in: PubMed
      7. Bayer AS, Mishra NN, Sakoulas G, Nonejuie P, Nast CC, Pogliano J, Chen KT, Ellison SN, Yeaman MR, Yang SJ. Heterogeneity of mprF Sequences in Methicillin-Resistant Staphylococcus aureus Clinical Isolates: Role in Cross-Resistance between Daptomycin and Host Defense Antimicrobial Peptides. Antimicrob Agents Chemother. 2014 Dec; 58(12):7462-7. PMID: 25288091.
        View in: PubMed
      8. Sakoulas G, Moise PA, Casapao AM, Nonejuie P, Olson J, Okumura CY, Rybak MJ, Kullar R, Dhand A, Rose WE, Goff DA, Bressler AM, Lee Y, Pogliano J, Johns S, Kaatz GW, Ebright JR, Nizet V. Antimicrobial Salvage Therapy for Persistent Staphylococcal Bacteremia Using Daptomycin Plus Ceftaroline. Clin Ther. 2014 Jul 10. PMID: 25017183.
        View in: PubMed
      9. Barber KE, Werth BJ, Ireland CE, Stone NE, Nonejuie P, Sakoulas G, Pogliano J, Rybak MJ. Potent synergy of ceftobiprole plus daptomycin against multiple strains of Staphylococcus aureus with various resistance phenotypes. J Antimicrob Chemother. 2014 Nov; 69(11):3006-10. PMID: 24990867.
        View in: PubMed
      10. Sakoulas G, Rose W, Nonejuie P, Olson J, Pogliano J, Humphries R, Nizet V. Ceftaroline Restores Daptomycin Activity against Daptomycin-Nonsusceptible Vancomycin-Resistant Enterococcus faecium. Antimicrob Agents Chemother. 2014 Mar; 58(3):1494-500. PMID: 24366742.
        View in: PubMed
      11. Sakoulas G, Okumura CY, Thienphrapa W, Olson J, Nonejuie P, Dam Q, Dhand A, Pogliano J, Yeaman MR, Hensler ME, Bayer AS, Nizet V. Nafcillin enhances innate immune-mediated killing of methicillin-resistant Staphylococcus aureus. J Mol Med (Berl). 2014 Feb; 92(2):139-49. PMID: 24297496.
        View in: PubMed
      12. Sakoulas G, Nonejuie P, Nizet V, Pogliano J, Crum-Cianflone N, Haddad F. Treatment of high-level gentamicin-resistant Enterococcus faecalis endocarditis with daptomycin plus ceftaroline. Antimicrob Agents Chemother. 2013 Aug; 57(8):4042-5. PMID: 23689728.
        View in: PubMed
      13. Dedrick RM, Marinelli LJ, Newton GL, Pogliano K, Pogliano J, Hatfull GF. Functional requirements for bacteriophage growth: gene essentiality and expression in mycobacteriophage Giles. Mol Microbiol. 2013 May; 88(3):577-89. PMID: 23560716.
        View in: PubMed
      14. Werth BJ, Sakoulas G, Rose WE, Pogliano J, Tewhey R, Rybak MJ. Ceftaroline increases membrane binding and enhances the activity of daptomycin against daptomycin-nonsusceptible vancomycin-intermediate Staphylococcus aureus in a pharmacokinetic/pharmacodynamic model. Antimicrob Agents Chemother. 2013 Jan; 57(1):66-73. PMID: 23070161.
        View in: PubMed
      15. Pogliano J, Pogliano N, Silverman JA. Daptomycin-mediated reorganization of membrane architecture causes mislocalization of essential cell division proteins. J Bacteriol. 2012 Sep; 194(17):4494-504. PMID: 22661688.
        View in: PubMed
      16. Sakoulas G, Bayer AS, Pogliano J, Tsuji BT, Yang SJ, Mishra NN, Nizet V, Yeaman MR, Moise PA. Ampicillin enhances daptomycin- and cationic host defense peptide-mediated killing of ampicillin- and vancomycin-resistant Enterococcus faecium. Antimicrob Agents Chemother. 2012 Feb; 56(2):838-44. PMID: 22123698.
        View in: PubMed
      17. Dhand A, Bayer AS, Pogliano J, Yang SJ, Bolaris M, Nizet V, Wang G, Sakoulas G. Use of antistaphylococcal beta-lactams to increase daptomycin activity in eradicating persistent bacteremia due to methicillin-resistant Staphylococcus aureus: role of enhanced daptomycin binding. Clin Infect Dis. 2011 Jul 15; 53(2):158-63. PMID: 21690622.
        View in: PubMed
      18. Pogliano J. The bacterial cytoskeleton. Curr Opin Cell Biol. 2008 Feb; 20(1):19-27. PMID: 18243677.
        View in: PubMed
      Joseph's Networks
      Concepts
      Derived automatically from this person's publications.
      _
      Co-Authors
      People in Profiles who have published with this person.
      _
      Similar People
      People who share similar concepts with this person.
      _
      Same Department
      Physical Neighbors
      People whose addresses are nearby this person.
      _