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    Kuo Lee

    TitleAdjunct Professor
    SchoolUniversity of California, San Diego
    Address9500 Gilman Drive #0932
    CA La Jolla 92093
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Xu J, de Winter F, Farrokhi C, Rockenstein E, Mante M, Adame A, Cook J, Jin X, Masliah E, Lee K. Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer's disease model. Sci Rep. 2016 Aug 25; 6:31692. PMID: 27558862; PMCID: PMC4997345.
      2. Mo AH, Landon PB, Gomez KS, Kang H, Lee J, Zhang C, Janetanakit W, Sant V, Lu T, Colburn DA, Akkiraju S, Dossou S, Cao Y, Lee K, Varghese S, Glinsky G, Lal R. Magnetically-responsive silica-gold nanobowls for targeted delivery and SERS-based sensing. Nanoscale. 2016 Jun 09; 8(23):11840-50. PMID: 27228391.
        View in: PubMed
      3. Amin ND, Bai G, Klug JR, Bonanomi D, Pankratz MT, Gifford WD, Hinckley CA, Sternfeld MJ, Driscoll SP, Dominguez B, Lee K, Jin X, Pfaff SL. Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure. Science. 2015 Dec 18; 350(6267):1525-9. PMID: 26680198; PMCID: PMC4913787 [Available on 12/18/16].
      4. Vilar M, Sung TC, Chen Z, García-Carpio I, Fernandez EM, Xu J, Riek R, Lee K. Heterodimerization of p45-p75 modulates p75 signaling: structural basis and mechanism of action. PLoS Biol. 2014 Aug; 12(8):e1001918. PMID: 25093680; PMCID: PMC4122344.
      5. Sung TC, Chen Z, Thuret S, Vilar M, Gage FH, Riek R, Lee K. P45 forms a complex with FADD and promotes neuronal cell survival following spinal cord injury. PLoS One. 2013; 8(7):e69286. PMID: 23935974; PMCID: PMC3720591.
      6. Seidel S, Bruce J, Leblanc M, Lee K, Fan H, Ahlquist P, Young JA. ZASC1 knockout mice exhibit an early bone marrow-specific defect in murine leukemia virus replication. Virol J. 2013 Apr 24; 10:130. PMID: 23617998; PMCID: PMC3654992.
      7. Morello CS, Kraynyak KA, Levinson MS, Chen Z, Lee K, Spector DH. Inactivated HSV-2 in MPL/alum adjuvant provides nearly complete protection against genital infection and shedding following long term challenge and rechallenge. Vaccine. 2012 Oct 12; 30(46):6541-6550. PMID: 22947141; PMCID: PMC3754855.
      8. Montminy M, Lee K, Rivier JE, Rivier C, Reichlin S. Wylie Vale: neuroendocrine master. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3604-5. PMID: 22355104; PMCID: PMC3309770.
      9. Yang J, Dominguez B, de Winter F, Gould TW, Eriksson JE, Lee K. Nestin negatively regulates postsynaptic differentiation of the neuromuscular synapse. Nat Neurosci. 2011 Mar; 14(3):324-30. PMID: 21278733; PMCID: PMC3069133.
      10. An MC, Lin W, Yang J, Dominguez B, Padgett D, Sugiura Y, Aryal P, Gould TW, Oppenheim RW, Hester ME, Kaspar BK, Ko CP, Lee K. Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10702-7. PMID: 20498043; PMCID: PMC2890820.
      11. Bengoechea TG, Chen Z, O'Leary DA, O'Leary D, Masliah E, Lee K. p75 reduces beta-amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model. Proc Natl Acad Sci U S A. 2009 May 12; 106(19):7870-5. PMID: 19416837; PMCID: PMC2683130.
      12. Lim YS, McLaughlin T, Sung TC, Santiago A, Lee K, O'Leary DD. p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping. Neuron. 2008 Sep 11; 59(5):746-58. PMID: 18786358; PMCID: PMC2677386.
      13. Wang W, Takimoto JK, Louie GV, Baiga TJ, Noel JP, Lee K, Slesinger PA, Wang L. Genetically encoding unnatural amino acids for cellular and neuronal studies. Nat Neurosci. 2007 Aug; 10(8):1063-72. PMID: 17603477; PMCID: PMC2692200.
      14. Rissman RA, Lee K, Vale W, Sawchenko PE. Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation. J Neurosci. 2007 Jun 13; 27(24):6552-62. PMID: 17567816.
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      15. Li C, Chen P, Vaughan J, Lee K, Vale W. Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):4206-11. PMID: 17360501; PMCID: PMC1820733.
      16. Negro A, Brar BK, Gu Y, Peterson KL, Vale W, Lee K. erbB2 is required for G protein-coupled receptor signaling in the heart. Proc Natl Acad Sci U S A. 2006 Oct 24; 103(43):15889-93. PMID: 17043217; PMCID: PMC1635098.
      17. Chen A, Zorrilla E, Smith S, Rousso D, Levy C, Vaughan J, Donaldson C, Roberts A, Lee K, Vale W. Urocortin 2-deficient mice exhibit gender-specific alterations in circadian hypothalamus-pituitary-adrenal axis and depressive-like behavior. J Neurosci. 2006 May 17; 26(20):5500-10. PMID: 16707802.
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      18. Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee K. Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron. 2005 May 19; 46(4):569-79. PMID: 15944126.
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      19. Myers CP, Lewcock JW, Hanson MG, Gosgnach S, Aimone JB, Gage FH, Lee K, Landmesser LT, Pfaff SL. Cholinergic input is required during embryonic development to mediate proper assembly of spinal locomotor circuits. Neuron. 2005 Apr 07; 46(1):37-49. PMID: 15820692.
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      20. Wang P, Yang G, Mosier DR, Chang P, Zaidi T, Gong YD, Zhao NM, Dominguez B, Lee K, Gan WB, Zheng H. Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2. J Neurosci. 2005 Feb 02; 25(5):1219-25. PMID: 15689559.
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      21. Joseph NM, Mukouyama YS, Mosher JT, Jaegle M, Crone SA, Dormand EL, Lee K, Meijer D, Anderson DJ, Morrison SJ. Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells. Development. 2004 Nov; 131(22):5599-612. PMID: 15496445; PMCID: PMC2638001.
      22. Bale TL, Hoshijima M, Gu Y, Dalton N, Anderson KR, Lee K, Rivier J, Chien KR, Vale WW, Peterson KL. The cardiovascular physiologic actions of urocortin II: acute effects in murine heart failure. Proc Natl Acad Sci U S A. 2004 Mar 09; 101(10):3697-702. PMID: 14990799; PMCID: PMC373525.
      23. Negro A, Brar BK, Lee K. Essential roles of Her2/erbB2 in cardiac development and function. Recent Prog Horm Res. 2004; 59:1-12. PMID: 14749494.
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      24. Brar BK, Jonassen AK, Egorina EM, Chen A, Negro A, Perrin MH, Mjøs OD, Latchman DS, Lee K, Vale W. Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: an essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart. Endocrinology. 2004 Jan; 145(1):24-35; discussion 21-3. PMID: 12970163.
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      25. Bale TL, Anderson KR, Roberts AJ, Lee K, Nagy TR, Vale WW. Corticotropin-releasing factor receptor-2-deficient mice display abnormal homeostatic responses to challenges of increased dietary fat and cold. Endocrinology. 2003 Jun; 144(6):2580-7. PMID: 12746321.
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      26. Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie BD, Willhoite AR, Muotri AR, Summers RG, Chun J, Lee K, Gage FH. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6777-82. PMID: 12748381; PMCID: PMC164523.
      27. Brandon EP, Lin W, D'Amour KA, Pizzo DP, Dominguez B, Sugiura Y, Thode S, Ko CP, Thal LJ, Gage FH, Lee K. Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice. J Neurosci. 2003 Jan 15; 23(2):539-49. PMID: 12533614.
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      28. Crone SA, Negro A, Trumpp A, Giovannini M, Lee K. Colonic epithelial expression of ErbB2 is required for postnatal maintenance of the enteric nervous system. Neuron. 2003 Jan 09; 37(1):29-40. PMID: 12526770.
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      29. Crone SA, Lee K. The bound leading the bound: target-derived receptors act as guidance cues. Neuron. 2002 Oct 24; 36(3):333-5. PMID: 12408835.
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      30. Crone SA, Lee K. Gene targeting reveals multiple essential functions of the neuregulin signaling system during development of the neuroendocrine and nervous systems. Ann N Y Acad Sci. 2002 Oct; 971:547-53. PMID: 12438181.
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      31. Vetter DE, Li C, Zhao L, Contarino A, Liberman MC, Smith GW, Marchuk Y, Koob GF, Heinemann SF, Vale W, Lee K. Urocortin-deficient mice show hearing impairment and increased anxiety-like behavior. Nat Genet. 2002 Aug; 31(4):363-9. PMID: 12091910.
        View in: PubMed
      32. Bale TL, Lee K, Vale WW. The role of corticotropin-releasing factor receptors in stress and anxiety. Integr Comp Biol. 2002 Jul; 42(3):552-5. PMID: 21708750.
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      33. Bale TL, Giordano FJ, Hickey RP, Huang Y, Nath AK, Peterson KL, Vale WW, Lee K. Corticotropin-releasing factor receptor 2 is a tonic suppressor of vascularization. Proc Natl Acad Sci U S A. 2002 May 28; 99(11):7734-9. PMID: 12032352; PMCID: PMC124337.
      34. Kaspar BK, Vissel B, Bengoechea T, Crone S, Randolph-Moore L, Muller R, Brandon EP, Schaffer D, Verma IM, Lee K, Heinemann SF, Gage FH. Adeno-associated virus effectively mediates conditional gene modification in the brain. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):2320-5. PMID: 11842206; PMCID: PMC122363.
      35. Bale TL, Picetti R, Contarino A, Koob GF, Vale WW, Lee K. Mice deficient for both corticotropin-releasing factor receptor 1 (CRFR1) and CRFR2 have an impaired stress response and display sexually dichotomous anxiety-like behavior. J Neurosci. 2002 Jan 01; 22(1):193-9. PMID: 11756502.
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