Robert Langer

Title(s)Senate Emeritus, Family Medicine and Public Health
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Clinical and Translational Research Infrastructure Network IDeA-CTR
    NIH U54GM104944Sep 15, 2013 - Jun 30, 2023
    Role: Co-Principal Investigator
    NIH/WHI N01WH032120Apr 30, 1993 - Sep 14, 2005
    Role: Principal Investigator
    NIH R01HL044689Jan 1, 1991 - Dec 31, 1993
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Author Correction: Modeling of intracranial tumor treating fields for the treatment of complex high-grade gliomas. Sci Rep. 2023 Mar 09; 13(1):3955. Segar DJ, Bernstock JD, Arnaout O, Bi WL, Friedman GK, Langer R, Traverso G, Rampersad SM. PMID: 36894660; PMCID: PMC9998856.
      View in: PubMed   Mentions:    Fields:    
    2. Modeling of intracranial tumor treating fields for the treatment of complex high-grade gliomas. Sci Rep. 2023 01 30; 13(1):1636. Segar DJ, Bernstock JD, Arnaout O, Bi WL, Friedman GK, Langer R, Traverso G, Rampersad SM. PMID: 36717682; PMCID: PMC9886948.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. The landscape of mRNA nanomedicine. Nat Med. 2022 Nov; 28(11):2273-2287. Huang X, Kong N, Zhang X, Cao Y, Langer R, Tao W. PMID: 36357682.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    4. Partially Oxidized Alginate as a Biodegradable Carrier for Glucose-Responsive Insulin Delivery and Islet Cell Replacement Therapy. Adv Healthc Mater. 2023 01; 12(2):e2201822. Volpatti LR, Bochenek MA, Facklam AL, Burns DM, MacIsaac C, Morgart A, Walters B, Langer R, Anderson DG. PMID: 36325648; PMCID: PMC9840661.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Delivery of therapeutic carbon monoxide by gas-entrapping materials. Sci Transl Med. 2022 06 29; 14(651):eabl4135. Byrne JD, Gallo D, Boyce H, Becker SL, Kezar KM, Cotoia AT, Feig VR, Lopes A, Csizmadia E, Longhi MS, Lee JS, Kim H, Wentworth AJ, Shankar S, Lee GR, Bi J, Witt E, Ishida K, Hayward A, Kuosmanen JLP, Jenkins J, Wainer J, Aragon A, Wong K, Steiger C, Jeck WR, Bosch DE, Coleman MC, Spitz DR, Tift M, Langer R, Otterbein LE, Traverso G. PMID: 35767653; PMCID: PMC9576196.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    6. Platform for the Delivery of Unformulated RNA In Vivo. J Pharm Sci. 2022 06; 111(6):1770-1775. France MM, Rio TD, Travers H, Raftery E, Langer R, Traverso G, Schoellhammer CM. PMID: 34906584.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    7. A therapeutic convection-enhanced macroencapsulation device for enhancing β cell viability and insulin secretion. Proc Natl Acad Sci U S A. 2021 09 14; 118(37). Yang K, O'Cearbhaill ED, Liu SS, Zhou A, Chitnis GD, Hamilos AE, Xu J, Verma MKS, Giraldo JA, Kudo Y, Lee EA, Lee Y, Pop R, Langer R, Melton DA, Greiner DL, Karp JM. PMID: 34504013; PMCID: PMC8449352.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    8. Randomized Controlled Trial of a Dichoptic Digital Therapeutic for Amblyopia. Ophthalmology. 2022 01; 129(1):77-85. Xiao S, Angjeli E, Wu HC, Gaier ED, Gomez S, Travers DA, Binenbaum G, Langer R, Hunter DG, Repka MX, Luminopia Pivotal Trial Group. PMID: 34534556.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    9. Engineered insulin-polycation complexes for glucose-responsive delivery with high insulin loading. J Control Release. 2021 10 10; 338:71-79. Volpatti LR, Burns DM, Basu A, Langer R, Anderson DG. PMID: 34391834.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    10. Lipid nanoparticles for mRNA delivery. Nat Rev Mater. 2021; 6(12):1078-1094. Hou X, Zaks T, Langer R, Dong Y. PMID: 34394960; PMCID: PMC8353930.
      View in: PubMed   Mentions: 541  
    11. Author Correction: Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates. Nat Mater. 2021 Jul; 20(7):1038. Doloff JC, Veiseh O, Vegas AJ, Tam HH, Farah S, Ma M, Li J, Bader A, Chiu A, Sadraei A, Aresta-Dasilva S, Griffin M, Jhunjhunwala S, Webber M, Siebert S, Tang K, Chen M, Langan E, Dholakia N, Thakrar R, Qi M, Oberholzer J, Greiner DL, Langer R, Anderson DG. PMID: 34012046.
      View in: PubMed   Mentions:    Fields:    
    12. Exhaled aerosol increases with COVID-19 infection, age, and obesity. Proc Natl Acad Sci U S A. 2021 02 23; 118(8). Edwards DA, Ausiello D, Salzman J, Devlin T, Langer R, Beddingfield BJ, Fears AC, Doyle-Meyers LA, Redmann RK, Killeen SZ, Maness NJ, Roy CJ. PMID: 33563754; PMCID: PMC7923364.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    13. BBB pathophysiology-independent delivery of siRNA in traumatic brain injury. Sci Adv. 2021 01; 7(1). Li W, Qiu J, Li XL, Aday S, Zhang J, Conley G, Xu J, Joseph J, Lan H, Langer R, Mannix R, Karp JM, Joshi N. PMID: 33523853; PMCID: PMC7775748.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    14. Engineering precision nanoparticles for drug delivery. Nat Rev Drug Discov. 2021 02; 20(2):101-124. Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R. PMID: 33277608; PMCID: PMC7717100.
      View in: PubMed   Mentions: 1095     Fields:    Translation:Humans
    15. Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association. Circulation. 2020 12 22; 142(25):e506-e532. El Khoudary SR, Aggarwal B, Beckie TM, Hodis HN, Johnson AE, Langer RD, Limacher MC, Manson JE, Stefanick ML, Allison MA, American Heart Association Prevention Science Committee of the Council on Epidemiology and Preventio. PMID: 33251828.
      View in: PubMed   Mentions: 181     Fields:    Translation:HumansPHPublic Health
    16. Analysis of the Human Plasma Proteome Using Multi-Nanoparticle Protein Corona for Detection of Alzheimer's Disease. Adv Healthc Mater. 2021 01; 10(2):e2000948. Corbo C, Li AA, Poustchi H, Lee GY, Stacks S, Molinaro R, Ma P, Platt T, Behzadi S, Langer R, Farias V, Farokhzad OC. PMID: 33169521.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    17. Microgel encapsulated nanoparticles for glucose-responsive insulin delivery. Biomaterials. 2021 01; 267:120458. Volpatti LR, Facklam AL, Cortinas AB, Lu YC, Matranga MA, MacIsaac C, Hill MC, Langer R, Anderson DG. PMID: 33197650.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    18. Chemical Tuning of Fibers Drawn from Extensible Hyaluronic Acid Networks. J Am Chem Soc. 2020 11 18; 142(46):19715-19721. Chu CK, Joseph AJ, Limjoco MD, Yang J, Bose S, Thapa LS, Langer R, Anderson DG. PMID: 33141568; PMCID: PMC9455704.
      View in: PubMed   Mentions: 7     Fields:    
    19. A materials-science perspective on tackling COVID-19. Nat Rev Mater. 2020; 5(11):847-860. Tang Z, Kong N, Zhang X, Liu Y, Hu P, Mou S, Liljeström P, Shi J, Tan W, Kim JS, Cao Y, Langer R, Leong KW, Farokhzad OC, Tao W. PMID: 33078077; PMCID: PMC7556605.
      View in: PubMed   Mentions: 100  
    20. Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche. Nat Biomed Eng. 2020 11; 4(11):1076-1089. Krohn-Grimberghe M, Mitchell MJ, Schloss MJ, Khan OF, Courties G, Guimaraes PPG, Rohde D, Cremer S, Kowalski PS, Sun Y, Tan M, Webster J, Wang K, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Nayar R, Frodermann V, Hulsmans M, Chung A, Hoyer FF, Swirski FK, Langer R, Anderson DG, Nahrendorf M. PMID: 33020600; PMCID: PMC7655681.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    21. Corrigendum to "Advanced multimodal nanoparticles delay tumor progression withclinical radiation therapy" [Journal of Controlled Release 238 (2016) 103-133]. J Control Release. 2021 Jan 10; 329:1283-1285. Detappe A, Kunjachan S, Sancey L, Motto-Ros V, Biancur D, Drane P, Guieze R, Makrigiorgos GM, Tillement O, Langer R, Berbeco R. PMID: 32977991.
      View in: PubMed   Mentions:    Fields:    
    22. Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy. Sci Transl Med. 2020 08 12; 12(556). Lu X, Miao L, Gao W, Chen Z, McHugh KJ, Sun Y, Tochka Z, Tomasic S, Sadtler K, Hyacinthe A, Huang Y, Graf T, Hu Q, Sarmadi M, Langer R, Anderson DG, Jaklenec A. PMID: 32801144; PMCID: PMC9019818.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    23. Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing. ACS Nano. 2020 08 25; 14(8):9243-9262. Wei T, Cheng Q, Farbiak L, Anderson DG, Langer R, Siegwart DJ. PMID: 32697075; PMCID: PMC7996671.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    24. Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona. Nat Commun. 2020 07 22; 11(1):3662. Blume JE, Manning WC, Troiano G, Hornburg D, Figa M, Hesterberg L, Platt TL, Zhao X, Cuaresma RA, Everley PA, Ko M, Liou H, Mahoney M, Ferdosi S, Elgierari EM, Stolarczyk C, Tangeysh B, Xia H, Benz R, Siddiqui A, Carr SA, Ma P, Langer R, Farias V, Farokhzad OC. PMID: 32699280; PMCID: PMC7376165.
      View in: PubMed   Mentions: 68     Fields:    Translation:Humans
    25. Vascularized Muscle Flap to Reduce Wound Breakdown During Flexible Electrode-Mediated Functional Electrical Stimulation After Peripheral Nerve Injury. Front Neurol. 2020; 11:644. McAvoy M, Doloff JC, Khan OF, Rosen J, Langer R, Anderson DG. PMID: 32793094; PMCID: PMC7385241.
      View in: PubMed   Mentions:
    26. Cyclodextrins in drug delivery: applications in gene and combination therapy. Drug Deliv Transl Res. 2020 06; 10(3):661-677. Haley RM, Gottardi R, Langer R, Mitchell MJ. PMID: 32077052; PMCID: PMC7524011.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    27. A Nanoprimer To Improve the Systemic Delivery of siRNA and mRNA. Nano Lett. 2020 06 10; 20(6):4264-4269. Saunders NRM, Paolini MS, Fenton OS, Poul L, Devalliere J, Mpambani F, Darmon A, Bergère M, Jibault O, Germain M, Langer R. PMID: 32357299.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    28. A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells. Nat Biomed Eng. 2020 08; 4(8):814-826. Bose S, Volpatti LR, Thiono D, Yesilyurt V, McGladrigan C, Tang Y, Facklam A, Wang A, Jhunjhunwala S, Veiseh O, Hollister-Lock J, Bhattacharya C, Weir GC, Greiner DL, Langer R, Anderson DG. PMID: 32231313; PMCID: PMC8051527.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    29. Machine Learning Uncovers Food- and Excipient-Drug Interactions. Cell Rep. 2020 03 17; 30(11):3710-3716.e4. Reker D, Shi Y, Kirtane AR, Hess K, Zhong GJ, Crane E, Lin CH, Langer R, Traverso G. PMID: 32187543; PMCID: PMC7179333.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    30. Magnetic Retrieval of Encapsulated Beta Cell Transplants from Diabetic Mice Using Dual-Function MRI Visible and Retrievable Microcapsules. Adv Mater. 2020 Apr; 32(16):e1904502. Delcassian D, Luzhansky I, Spanoudaki V, Bochenek M, McGladrigan C, Nguyen A, Norcross S, Zhu Y, Shan CS, Hausser R, Shakesheff KM, Langer R, Anderson DG. PMID: 32134138.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    31. Glucose-Responsive Nanoparticles for Rapid and Extended Self-Regulated Insulin Delivery. ACS Nano. 2020 01 28; 14(1):488-497. Volpatti LR, Matranga MA, Cortinas AB, Delcassian D, Daniel KB, Langer R, Anderson DG. PMID: 31765558.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    32. In Vivo RNAi-Mediated eIF3m Knockdown Affects Ribosome Biogenesis and Transcription but Has Limited Impact on mRNA-Specific Translation. Mol Ther Nucleic Acids. 2020 Mar 06; 19:252-266. Smekalova EM, Gerashchenko MV, O'Connor PBF, Whittaker CA, Kauffman KJ, Fefilova AS, Zatsepin TS, Bogorad RL, Baranov PV, Langer R, Gladyshev VN, Anderson DG, Koteliansky V. PMID: 31855834; PMCID: PMC6926209.
      View in: PubMed   Mentions: 8  
    33. A crosslinked polymer skin barrier film for moderate to severe atopic dermatitis: A pilot study in adults. J Am Acad Dermatol. 2020 Apr; 82(4):895-901. Bouthillette M, Beccati D, Akthakul A, Ramadurai N, Nashat A, Langer R, Anderson RR, Sakamoto FH. PMID: 31589946.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation. Nat Biotechnol. 2019 10; 37(10):1174-1185. Miao L, Li L, Huang Y, Delcassian D, Chahal J, Han J, Shi Y, Sadtler K, Gao W, Lin J, Doloff JC, Langer R, Anderson DG. PMID: 31570898.
      View in: PubMed   Mentions: 160     Fields:    Translation:HumansAnimalsCells
    35. Flexible Multielectrode Array for Skeletal Muscle Conditioning, Acetylcholine Receptor Stabilization and Epimysial Recording After Critical Peripheral Nerve Injury. Theranostics. 2019; 9(23):7099-7107. McAvoy M, Tsosie JK, Vyas KN, Khan OF, Sadtler K, Langer R, Anderson DG. PMID: 31660089; PMCID: PMC6815960.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    36. Using Large Datasets to Understand Nanotechnology. Adv Mater. 2019 Oct; 31(43):e1902798. Paunovska K, Loughrey D, Sago CD, Langer R, Dahlman JE. PMID: 31429126; PMCID: PMC6810779.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    37. Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations. Nat Mater. 2019 08; 18(8):892-904. Farah S, Doloff JC, Müller P, Sadraei A, Han HJ, Olafson K, Vyas K, Tam HH, Hollister-Lock J, Kowalski PS, Griffin M, Meng A, McAvoy M, Graham AC, McGarrigle J, Oberholzer J, Weir GC, Greiner DL, Langer R, Anderson DG. PMID: 31235902; PMCID: PMC7184801.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    38. BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension. Circulation. 2019 05 07; 139(19):2238-2255. Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE, Sugahara M, Kagiyama N, Satoh T, Zhang M, Feng N, Gorcsan J, Vargas SO, Haley KJ, Kumar R, Graham BB, Langer R, Anderson DG, Wang B, Shiva S, Bertero T, Chan SY. PMID: 30759996; PMCID: PMC6519484.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    39. Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy. Proc Natl Acad Sci U S A. 2019 05 28; 116(22):10674-10680. Chauhan VP, Chen IX, Tong R, Ng MR, Martin JD, Naxerova K, Wu MW, Huang P, Boucher Y, Kohane DS, Langer R, Jain RK. PMID: 31040208; PMCID: PMC6561160.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    40. Polyimide Electrode-Based Electrical Stimulation Impedes Early Stage Muscle Graft Regeneration. Front Neurol. 2019; 10:252. Srinivasan S, Vyas K, McAvoy M, Calvaresi P, Khan OF, Langer R, Anderson DG, Herr H. PMID: 30967830; PMCID: PMC6438882.
      View in: PubMed   Mentions: 4  
    41. Delivery technologies for cancer immunotherapy. Nat Rev Drug Discov. 2019 03; 18(3):175-196. Riley RS, June CH, Langer R, Mitchell MJ. PMID: 30622344; PMCID: PMC6410566.
      View in: PubMed   Mentions: 681     Fields:    Translation:HumansAnimalsCells
    42. Simultaneous spatiotemporal tracking and oxygen sensing of transient implants in vivo using hot-spot MRI and machine learning. Proc Natl Acad Sci U S A. 2019 03 12; 116(11):4861-4870. Spanoudaki V, Doloff JC, Huang W, Norcross SR, Farah S, Langer R, Anderson DG. PMID: 30808810; PMCID: PMC6421446.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    43. Steroid pretreatment of organ donors does not impact on early rejection and long-term kidney allograft survival: Results from a multicenter randomized, controlled trial. Am J Transplant. 2019 06; 19(6):1770-1776. Reindl-Schwaighofer R, Kainz A, Jelencsics K, Heinzel A, Berlakovich G, Remport Á, Heinze G, Langer R, Oberbauer R. PMID: 30614649; PMCID: PMC6563104.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    44. Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer. Proc Natl Acad Sci U S A. 2019 03 05; 116(10):4558-4566. Chen IX, Chauhan VP, Posada J, Ng MR, Wu MW, Adstamongkonkul P, Huang P, Lindeman N, Langer R, Jain RK. PMID: 30700545; PMCID: PMC6410779.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansAnimalsCells
    45. Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium. Adv Mater. 2019 Feb; 31(8):e1805116. Patel AK, Kaczmarek JC, Bose S, Kauffman KJ, Mir F, Heartlein MW, DeRosa F, Langer R, Anderson DG. PMID: 30609147; PMCID: PMC7490222.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    46. Author Correction: Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Nat Biomed Eng. 2018 Dec; 2(12):968. Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J. PMID: 31015729.
      View in: PubMed   Mentions: 3     Fields:    
    47. Publisher Correction: Engineering and physical sciences in oncology: challenges and opportunities. Nat Rev Cancer. 2018 11; 18(11):720. Mitchell MJ, Jain RK, Langer R. PMID: 30337715; PMCID: PMC6357229.
      View in: PubMed   Mentions:    Fields:    
    48. In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy. Analyst. 2018 Oct 08; 143(20):4836-4839. Jonas O, Kang JW, Singh SP, Lammers A, Nguyen FT, Dasari RR, So PTC, Langer R, Cima MJ. PMID: 30070266; PMCID: PMC6175619.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    49. Potent in vivo lung cancer Wnt signaling inhibition via cyclodextrin-LGK974 inclusion complexes. J Control Release. 2018 11 28; 290:75-87. Guimaraes PPG, Tan M, Tammela T, Wu K, Chung A, Oberli M, Wang K, Spektor R, Riley RS, Viana CTR, Jacks T, Langer R, Mitchell MJ. PMID: 30290244; PMCID: PMC6441337.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    50. Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Nat Biomed Eng. 2018 11; 2(11):850-864. Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J. PMID: 31015614; PMCID: PMC6486184.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    51. Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques. Nat Biomed Eng. 2018 Nov; 2(11):810-821. Bochenek MA, Veiseh O, Vegas AJ, McGarrigle JJ, Qi M, Marchese E, Omami M, Doloff JC, Mendoza-Elias J, Nourmohammadzadeh M, Khan A, Yeh CC, Xing Y, Isa D, Ghani S, Li J, Landry C, Bader AR, Olejnik K, Chen M, Hollister-Lock J, Wang Y, Greiner DL, Weir GC, Strand BL, Rokstad AMA, Lacik I, Langer R, Anderson DG, Oberholzer J. PMID: 30873298; PMCID: PMC6413527.
      View in: PubMed   Mentions: 100     Fields:    
    52. Genotype-targeted local therapy of glioma. Proc Natl Acad Sci U S A. 2018 09 04; 115(36):E8388-E8394. Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, Wojtkiewicz GR, Baig A, Francis JM, Rinne ML, Batten JM, Batchelor TT, Brastianos PK, Curry WT, Barker FG, Jordan JT, Iafrate AJ, Chi AS, Lennerz JK, Meyerson M, Langer R, Wakimoto H, Traverso G, Cahill DP. PMID: 30082399; PMCID: PMC6130372.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    53. Reduction of measurement noise in a continuous glucose monitor by coating the sensor with a zwitterionic polymer. Nat Biomed Eng. 2018 12; 2(12):894-906. Xie X, Doloff JC, Yesilyurt V, Sadraei A, McGarrigle JJ, Omami M, Veiseh O, Farah S, Isa D, Ghani S, Joshi I, Vegas A, Li J, Wang W, Bader A, Tam HH, Tao J, Chen HJ, Yang B, Williamson KA, Oberholzer J, Langer R, Anderson DG. PMID: 30931173; PMCID: PMC6436621.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    54. Ionizable Amino-Polyesters Synthesized via Ring Opening Polymerization of Tertiary Amino-Alcohols for Tissue Selective mRNA Delivery. Adv Mater. 2018 Jul 05; e1801151. Kowalski PS, Capasso Palmiero U, Huang Y, Rudra A, Langer R, Anderson DG. PMID: 29975801; PMCID: PMC6320729.
      View in: PubMed   Mentions: 36     Fields:    
    55. Endothelial siRNA delivery in nonhuman primates using ionizable low-molecular weight polymeric nanoparticles. Sci Adv. 2018 06; 4(6):eaar8409. Khan OF, Kowalski PS, Doloff JC, Tsosie JK, Bakthavatchalu V, Winn CB, Haupt J, Jamiel M, Langer R, Anderson DG. PMID: 29963629; PMCID: PMC6021147.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    56. Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types. BMC Biol. 2018 06 05; 16(1):62. Mead BE, Ordovas-Montanes J, Braun AP, Levy LE, Bhargava P, Szucs MJ, Ammendolia DA, MacMullan MA, Yin X, Hughes TK, Wadsworth MH, Ahmad R, Rakoff-Nahoum S, Carr SA, Langer R, Collins JJ, Shalek AK, Karp JM. PMID: 29871632; PMCID: PMC5989470.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    57. Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics. Nanomaterials (Basel). 2018 May 03; 8(5). van der Valk DC, van der Ven CFT, Blaser MC, Grolman JM, Wu PJ, Fenton OS, Lee LH, Tibbitt MW, Andresen JL, Wen JR, Ha AH, Buffolo F, van Mil A, Bouten CVC, Body SC, Mooney DJ, Sluijter JPG, Aikawa M, Hjortnaes J, Langer R, Aikawa E. PMID: 29751516; PMCID: PMC5977310.
      View in: PubMed   Mentions: 33  
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    319. Conjugated equine estrogens and breast cancer risk in the Women's Health Initiative clinical trial and observational study. Am J Epidemiol. 2008 Jun 15; 167(12):1407-15. Prentice RL, Chlebowski RT, Stefanick ML, Manson JE, Langer RD, Pettinger M, Hendrix SL, Hubbell FA, Kooperberg C, Kuller LH, Lane DS, McTiernan A, O'Sullivan MJ, Rossouw JE, Anderson GL. PMID: 18448442; PMCID: PMC2703736.
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    320. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat Biotechnol. 2008 May; 26(5):561-9. Akinc A, Zumbuehl A, Goldberg M, Leshchiner ES, Busini V, Hossain N, Bacallado SA, Nguyen DN, Fuller J, Alvarez R, Borodovsky A, Borland T, Constien R, de Fougerolles A, Dorkin JR, Narayanannair Jayaprakash K, Jayaraman M, John M, Koteliansky V, Manoharan M, Nechev L, Qin J, Racie T, Raitcheva D, Rajeev KG, Sah DW, Soutschek J, Toudjarska I, Vornlocher HP, Zimmermann TS, Langer R, Anderson DG. PMID: 18438401; PMCID: PMC3014085.
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    321. Usefulness of baseline lipids and C-reactive protein in women receiving menopausal hormone therapy as predictors of treatment-related coronary events. Am J Cardiol. 2008 Jun 01; 101(11):1599-1605. Bray PF, Larson JC, Lacroix AZ, Manson J, Limacher MC, Rossouw JE, Lasser NL, Lawson WE, Stefanick ML, Langer RD, Margolis KL, Women's Health Initiative Investigators. PMID: 18489937; PMCID: PMC3543778.
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    322. Nanomechanical control of cell rolling in two dimensions through surface patterning of receptors. Nano Lett. 2008 Apr; 8(4):1153-8. Karnik R, Hong S, Zhang H, Mei Y, Anderson DG, Karp JM, Langer R. PMID: 18321075; PMCID: PMC2911031.
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    323. Estrogen plus progestin and breast cancer detection by means of mammography and breast biopsy. Arch Intern Med. 2008 Feb 25; 168(4):370-7; quiz 345. Chlebowski RT, Anderson G, Pettinger M, Lane D, Langer RD, Gilligan MA, Gillian MA, Walsh BW, Chen C, McTiernan A, Women's Health Initiative Investigators. PMID: 18299491.
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    324. Nanoparticle delivery of suicide DNA for epithelial ovarian cancer therapy. Adv Exp Med Biol. 2008; 622:209-19. Sawicki JA, Anderson DG, Langer R. PMID: 18546630.
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    325. New frontiers in nanotechnology for cancer treatment. Urol Oncol. 2008 Jan-Feb; 26(1):74-85. Alexis F, Rhee JW, Richie JP, Radovic-Moreno AF, Langer R, Farokhzad OC. PMID: 18190835.
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    326. Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol. 2007 Dec; 2(12):751-60. Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, Langer R. PMID: 18654426.
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    327. Self-reported sleep latency in postmenopausal women. J Korean Med Sci. 2007 Dec; 22(6):1007-14. Park DH, Kripke DF, Louis GJ, Elliott JA, Klauber MR, Rex KM, Tuunainen A, Langer RD. PMID: 18162715; PMCID: PMC2694625.
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    328. TOF-SIMS analysis of a 576 micropatterned copolymer array to reveal surface moieties that control wettability. Anal Chem. 2008 Jan 01; 80(1):135-42. Urquhart AJ, Taylor M, Anderson DG, Langer R, Davies MC, Alexander MR. PMID: 18044847.
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    329. Gene delivery properties of end-modified poly(beta-amino ester)s. Bioconjug Chem. 2007 Nov-Dec; 18(6):1887-96. Zugates GT, Tedford NC, Zumbuehl A, Jhunjhunwala S, Kang CS, Griffith LG, Lauffenburger DA, Langer R, Anderson DG. PMID: 17929884.
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    330. Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway. Nature. 2007 Oct 11; 449(7163):745-7. John M, Constien R, Akinc A, Goldberg M, Moon YA, Spranger M, Hadwiger P, Soutschek J, Vornlocher HP, Manoharan M, Stoffel M, Langer R, Anderson DG, Horton JD, Koteliansky V, Bumcrot D. PMID: 17898712; PMCID: PMC3019095.
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    331. Intravitreal injections of GDNF-loaded biodegradable microspheres are neuroprotective in a rat model of glaucoma. Mol Vis. 2007 Sep 24; 13:1783-92. Jiang C, Moore MJ, Zhang X, Klassen H, Langer R, Young M. PMID: 17960131.
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    332. Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer. Nano Lett. 2007 Oct; 7(10):3065-70. Bagalkot V, Zhang L, Levy-Nissenbaum E, Jon S, Kantoff PW, Langer R, Farokhzad OC. PMID: 17854227.
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    333. Risk factors for chronic venous disease: the San Diego Population Study. J Vasc Surg. 2007 Aug; 46(2):331-7. Criqui MH, Denenberg JO, Bergan J, Langer RD, Fronek A. PMID: 17600666; PMCID: PMC2023874.
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    334. Estrogen therapy and coronary-artery calcification. N Engl J Med. 2007 Jun 21; 356(25):2591-602. Manson JE, Allison MA, Rossouw JE, Carr JJ, Langer RD, Hsia J, Kuller LH, Cochrane BB, Hunt JR, Ludlam SE, Pettinger MB, Gass M, Margolis KL, Nathan L, Ockene JK, Prentice RL, Robbins J, Stefanick ML, WHI and WHI-CACS Investigators. PMID: 17582069.
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    335. Nanoparticulate delivery of suicide DNA to murine prostate and prostate tumors. Prostate. 2007 Jun 01; 67(8):855-62. Peng W, Anderson DG, Bao Y, Padera RF, Langer R, Sawicki JA. PMID: 17427200.
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    336. Peritoneal adhesion prevention with an in situ cross-linkable hyaluronan gel containing tissue-type plasminogen activator in a rabbit repeated-injury model. Biomaterials. 2007 Sep; 28(25):3704-13. Yeo Y, Bellas E, Highley CB, Langer R, Kohane DS. PMID: 17512979.
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    337. Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells. Lab Chip. 2007 Jun; 7(6):786-94. Karp JM, Yeh J, Eng G, Fukuda J, Blumling J, Suh KY, Cheng J, Mahdavi A, Borenstein J, Langer R, Khademhosseini A. PMID: 17538722.
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    338. Ethnic-specific prevalence of peripheral arterial disease in the United States. Am J Prev Med. 2007 Apr; 32(4):328-33. Allison MA, Ho E, Denenberg JO, Langer RD, Newman AB, Fabsitz RR, Criqui MH. PMID: 17383564.
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    339. Rapid optimization of gene delivery by parallel end-modification of poly(beta-amino ester)s. Mol Ther. 2007 Jul; 15(7):1306-12. Zugates GT, Peng W, Zumbuehl A, Jhunjhunwala S, Huang YH, Langer R, Sawicki JA, Anderson DG. PMID: 17375071.
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    340. Electrostatic ligand coatings of nanoparticles enable ligand-specific gene delivery to human primary cells. Nano Lett. 2007 Apr; 7(4):874-9. Green JJ, Chiu E, Leshchiner ES, Shi J, Langer R, Anderson DG. PMID: 17362046.
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    341. Cardiovascular disease, its risk factors and treatment, and age-related macular degeneration: Women's Health Initiative Sight Exam ancillary study. Am J Ophthalmol. 2007 Mar; 143(3):473-83. Klein R, Deng Y, Klein BE, Hyman L, Seddon J, Frank RN, Wallace RB, Hendrix SL, Kuppermann BD, Langer RD, Kuller L, Brunner R, Johnson KC, Thomas AM, Haan M. PMID: 17317391; PMCID: PMC2812860.
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    342. Nanostructured materials for applications in drug delivery and tissue engineering. J Biomater Sci Polym Ed. 2007; 18(3):241-68. Goldberg M, Langer R, Jia X. PMID: 17471764; PMCID: PMC3017754.
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    343. Renal artery calcium: relationship to systemic calcified atherosclerosis. Vasc Med. 2006 Nov; 11(4):232-8. Allison MA, DiTomasso D, Criqui MH, Langer RD, Wright CM. PMID: 17390546.
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    344. Physical activity-mediated functional recovery after spinal cord injury: potential roles of neural stem cells. Regen Med. 2006 Nov; 1(6):763-76. Teng YD, Liao WL, Choi H, Konya D, Sabharwal S, Langer R, Sidman RL, Snyder EY, Frontera WR. PMID: 17465758.
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    345. Nanomedicine: developing smarter therapeutic and diagnostic modalities. Adv Drug Deliv Rev. 2006 Dec 01; 58(14):1456-9. Farokhzad OC, Langer R. PMID: 17070960.
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    346. Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials. 2007 Feb; 28(5):869-76. Cheng J, Teply BA, Sherifi I, Sung J, Luther G, Gu FX, Levy-Nissenbaum E, Radovic-Moreno AF, Langer R, Farokhzad OC. PMID: 17055572; PMCID: PMC2925222.
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    347. Synthesis of poly(beta-amino ester)s with thiol-reactive side chains for DNA delivery. J Am Chem Soc. 2006 Oct 04; 128(39):12726-34. Zugates GT, Anderson DG, Little SR, Lawhorn IE, Langer R. PMID: 17002366.
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    348. Impact of cyclooxygenase inhibitors in the Women's Health Initiative hormone trials: secondary analysis of a randomized trial. PLoS Clin Trials. 2006 Sep 29; 1(5):e26. Hsia J, Manson JE, Kuller L, Pettinger M, Choe JH, Langer RD, Limacher M, Oberman A, Ockene J, O'Sullivan MJ, Robinson JG, Women's Health Initiative Research. PMID: 17016543; PMCID: PMC1584256.
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    350. Biodegradable polymeric vectors for gene delivery to human endothelial cells. Bioconjug Chem. 2006 Sep-Oct; 17(5):1162-9. Green JJ, Shi J, Chiu E, Leshchiner ES, Langer R, Anderson DG. PMID: 16984124.
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    351. Effects of E2 and E2/norgestimate hormone therapy on elevated baseline lipids. J Reprod Med. 2006 Aug; 51(8):610-6. Langer RD, Friedman AJ. PMID: 16967629.
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    352. Heparin localization and fine structure regulate Burkitt's lymphoma growth. Biochem Biophys Res Commun. 2006 Sep 29; 348(3):850-6. Berry D, Lynn DM, Berry E, Sasisekharan R, Langer R. PMID: 16904641.
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    353. Effects of tibolone and continuous combined conjugated equine estrogen/medroxyprogesterone acetate on the endometrium and vaginal bleeding: results of the OPAL study. Am J Obstet Gynecol. 2006 Nov; 195(5):1320-7. Langer RD, Landgren BM, Rymer J, Helmond FA, OPAL Investigators. PMID: 16875644.
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    354. Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs: part 3. Therapeutic efficacy and safety studies in ovarian cancer xenograft model. Cancer Chemother Pharmacol. 2007 Mar; 59(4):477-84. Devalapally H, Shenoy D, Little S, Langer R, Amiji M. PMID: 16862429.
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    355. The association between aspirin use and the incidence of colorectal cancer in women. Am J Epidemiol. 2006 Sep 15; 164(6):567-75. Allison M, Garland C, Chlebowski R, Criqui M, Langer R, Wu L, Roy H, McTiernan A, Kuller L, Women's Health Initiative Investigators. PMID: 16847042.
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    356. Micromolding of shape-controlled, harvestable cell-laden hydrogels. Biomaterials. 2006 Nov; 27(31):5391-8. Yeh J, Ling Y, Karp JM, Gantz J, Chandawarkar A, Eng G, Blumling J, Langer R, Khademhosseini A. PMID: 16828863.
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    357. Direct confinement of individual viruses within polyethylene glycol (PEG) nanowells. Nano Lett. 2006 Jun; 6(6):1196-201. Suh KY, Khademhosseini A, Jon S, Langer R. PMID: 16771579.
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    358. Light exposure is related to social and emotional functioning and to quality of life in older women. Psychiatry Res. 2006 Jun 30; 143(1):35-42. Grandner MA, Kripke DF, Langer RD. PMID: 16725207; PMCID: PMC3685148.
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    359. Nanoparticle-aptamer bioconjugates for cancer targeting. Expert Opin Drug Deliv. 2006 May; 3(3):311-24. Farokhzad OC, Karp JM, Langer R. PMID: 16640493.
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    360. Biodegradable polymeric microspheres and nanospheres for drug delivery in the peritoneum. J Biomed Mater Res A. 2006 May; 77(2):351-61. Kohane DS, Tse JY, Yeo Y, Padera R, Shubina M, Langer R. PMID: 16425240.
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    361. Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc Natl Acad Sci U S A. 2006 Apr 18; 103(16):6315-20. Farokhzad OC, Cheng J, Teply BA, Sherifi I, Jon S, Kantoff PW, Richie JP, Langer R. PMID: 16606824; PMCID: PMC1458875.
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    362. Venous thrombosis and conjugated equine estrogen in women without a uterus. Arch Intern Med. 2006 Apr 10; 166(7):772-80. Curb JD, Prentice RL, Bray PF, Langer RD, Van Horn L, Barnabei VM, Bloch MJ, Cyr MG, Gass M, Lepine L, Rodabough RJ, Sidney S, Uwaifo GI, Rosendaal FR. PMID: 16606815.
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    363. Combined analysis of Women's Health Initiative observational and clinical trial data on postmenopausal hormone treatment and cardiovascular disease. Am J Epidemiol. 2006 Apr 01; 163(7):589-99. Prentice RL, Langer RD, Stefanick ML, Howard BV, Pettinger M, Anderson GL, Barad D, Curb JD, Kotchen J, Kuller L, Limacher M, Wactawski-Wende J, Women's Health Initiative Investigators. PMID: 16484450.
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    364. Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med. 2006 Feb 16; 354(7):684-96. Wactawski-Wende J, Kotchen JM, Anderson GL, Assaf AR, Brunner RL, O'Sullivan MJ, Margolis KL, Ockene JK, Phillips L, Pottern L, Prentice RL, Robbins J, Rohan TE, Sarto GE, Sharma S, Stefanick ML, Van Horn L, Wallace RB, Whitlock E, Bassford T, Beresford SA, Black HR, Bonds DE, Brzyski RG, Caan B, Chlebowski RT, Cochrane B, Garland C, Gass M, Hays J, Heiss G, Hendrix SL, Howard BV, Hsia J, Hubbell FA, Jackson RD, Johnson KC, Judd H, Kooperberg CL, Kuller LH, LaCroix AZ, Lane DS, Langer RD, Lasser NL, Lewis CE, Limacher MC, Manson JE, Women's Health Initiative Investigators. PMID: 16481636.
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    365. Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med. 2006 Feb 16; 354(7):669-83. Jackson RD, LaCroix AZ, Gass M, Wallace RB, Robbins J, Lewis CE, Bassford T, Beresford SA, Black HR, Blanchette P, Bonds DE, Brunner RL, Brzyski RG, Caan B, Cauley JA, Chlebowski RT, Cummings SR, Granek I, Hays J, Heiss G, Hendrix SL, Howard BV, Hsia J, Hubbell FA, Johnson KC, Judd H, Kotchen JM, Kuller LH, Langer RD, Lasser NL, Limacher MC, Ludlam S, Manson JE, Margolis KL, McGowan J, Ockene JK, O'Sullivan MJ, Phillips L, Prentice RL, Sarto GE, Stefanick ML, Van Horn L, Wactawski-Wende J, Whitlock E, Anderson GL, Assaf AR, Barad D, Women's Health Initiative Investigators. PMID: 16481635.
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    366. Conjugated equine estrogens and coronary heart disease: the Women's Health Initiative. Arch Intern Med. 2006 Feb 13; 166(3):357-65. Hsia J, Langer RD, Manson JE, Kuller L, Johnson KC, Hendrix SL, Pettinger M, Heckbert SR, Greep N, Crawford S, Eaton CB, Kostis JB, Caralis P, Prentice R, Women's Health Initiative Investigators. PMID: 16476878.
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    367. Low-fat dietary pattern and risk of colorectal cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA. 2006 Feb 08; 295(6):643-54. Beresford SA, Johnson KC, Ritenbaugh C, Lasser NL, Snetselaar LG, Black HR, Anderson GL, Assaf AR, Bassford T, Bowen D, Brunner RL, Brzyski RG, Caan B, Chlebowski RT, Gass M, Harrigan RC, Hays J, Heber D, Heiss G, Hendrix SL, Howard BV, Hsia J, Hubbell FA, Jackson RD, Kotchen JM, Kuller LH, LaCroix AZ, Lane DS, Langer RD, Lewis CE, Manson JE, Margolis KL, Mossavar-Rahmani Y, Ockene JK, Parker LM, Perri MG, Phillips L, Prentice RL, Robbins J, Rossouw JE, Sarto GE, Stefanick ML, Van Horn L, Vitolins MZ, Wactawski-Wende J, Wallace RB, Whitlock E. PMID: 16467233.
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    368. Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA. 2006 Feb 08; 295(6):629-42. Prentice RL, Caan B, Chlebowski RT, Patterson R, Kuller LH, Ockene JK, Margolis KL, Limacher MC, Manson JE, Parker LM, Paskett E, Phillips L, Robbins J, Rossouw JE, Sarto GE, Shikany JM, Stefanick ML, Thomson CA, Van Horn L, Vitolins MZ, Wactawski-Wende J, Wallace RB, Wassertheil-Smoller S, Whitlock E, Yano K, Adams-Campbell L, Anderson GL, Assaf AR, Beresford SA, Black HR, Brunner RL, Brzyski RG, Ford L, Gass M, Hays J, Heber D, Heiss G, Hendrix SL, Hsia J, Hubbell FA, Jackson RD, Johnson KC, Kotchen JM, LaCroix AZ, Lane DS, Langer RD, Lasser NL, Henderson MM. PMID: 16467232.
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    370. Mitral and aortic annular calcification are highly associated with systemic calcified atherosclerosis. Circulation. 2006 Feb 14; 113(6):861-6. Allison MA, Cheung P, Criqui MH, Langer RD, Wright CM. PMID: 16461818.
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    371. Should symptomatic menopausal women be offered hormone therapy? MedGenMed. 2006; 8(3):40. Lobo RA, Bélisle S, Creasman WT, Frankel NR, Goodman NF, Hall JE, Ivey SL, Kingsberg S, Langer R, Lehman R, McArthur DB, Montgomery-Rice V, Notelovitz M, Packin GS, Rebar RW, Rousseau M, Schenken RS, Schneider DL, Sherif K, Wysocki S. PMID: 17410686; PMCID: PMC1794325.
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    373. Direct patterning of mammalian cells onto porous tissue engineering substrates using agarose stamps. Biomaterials. 2005 Dec; 26(36):7636-41. Stevens MM, Mayer M, Anderson DG, Weibel DB, Whitesides GM, Langer R. PMID: 15979701.
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    374. Association between the ankle-brachial index and future coronary calcium (the Rancho Bernardo study). Am J Cardiol. 2006 Jan 15; 97(2):181-6. Allison MA, Laughlin GA, Barrett-Connor E, Langer R. PMID: 16442359.
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    375. Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs: part 2. In vivo distribution and tumor localization studies. Pharm Res. 2005 Dec; 22(12):2107-14. Shenoy D, Little S, Langer R, Amiji M. PMID: 16254763; PMCID: PMC1350958.
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    376. Biodegradable polymer composite grafts promote the survival and differentiation of retinal progenitor cells. Stem Cells. 2005 Nov-Dec; 23(10):1579-88. Tomita M, Lavik E, Klassen H, Zahir T, Langer R, Young MJ. PMID: 16293582.
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    377. Ethnicity and peripheral arterial disease: the San Diego Population Study. Circulation. 2005 Oct 25; 112(17):2703-7. Criqui MH, Vargas V, Denenberg JO, Ho E, Allison M, Langer RD, Gamst A, Bundens WP, Fronek A. PMID: 16246968.
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    378. Formulation and characterization of poly (beta amino ester) microparticles for genetic vaccine delivery. J Control Release. 2005 Oct 20; 107(3):449-62. Little SR, Lynn DM, Puram SV, Langer R. PMID: 16112767.
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    381. Atherosclerotic calcification and intimal medial thickness of the carotid arteries. Int J Cardiol. 2005 Aug 03; 103(1):98-104. Allison MA, Tiefenbrun J, Langer RD, Wright CM. PMID: 16061130.
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    384. Relationships between symptoms and venous disease: the San Diego population study. Arch Intern Med. 2005 Jun 27; 165(12):1420-4. Langer RD, Ho E, Denenberg JO, Fronek A, Allison M, Criqui MH. PMID: 15983292.
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    385. Baseline associations between postmenopausal hormone therapy and inflammatory, haemostatic, and lipid biomarkers of coronary heart disease. The Women's Health Initiative Observational Study. Thromb Haemost. 2005 Jun; 93(6):1108-16. Langer RD, Pradhan AD, Lewis CE, Manson JE, Rossouw JE, Hendrix SL, LaCroix AZ, Ridker PM. PMID: 15968396.
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    386. Risk of cardiovascular disease by hysterectomy status, with and without oophorectomy: the Women's Health Initiative Observational Study. Circulation. 2005 Mar 29; 111(12):1462-70. Howard BV, Kuller L, Langer R, Manson JE, Allen C, Assaf A, Cochrane BB, Larson JC, Lasser N, Rainford M, Van Horn L, Stefanick ML, Trevisan M, Women's Health Initiative. PMID: 15781742.
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    387. Postmenopausal hormone therapy: critical reappraisal and a unified hypothesis. Fertil Steril. 2005 Mar; 83(3):558-66. Phillips LS, Langer RD. PMID: 15749481.
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    388. Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters). Mol Ther. 2005 Mar; 11(3):426-34. Anderson DG, Akinc A, Hossain N, Langer R. PMID: 15727939.
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    389. Association between reported alcohol intake and cognition: results from the Women's Health Initiative Memory Study. Am J Epidemiol. 2005 Feb 01; 161(3):228-38. Espeland MA, Gu L, Masaki KH, Langer RD, Coker LH, Stefanick ML, Ockene J, Rapp SR. PMID: 15671255.
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    390. In vivo evaluation of tetrahedral amorphous carbon. Biomaterials. 2005 Feb; 26(5):465-73. LaVan DA, Padera RF, Friedmann TA, Sullivan JP, Langer R, Kohane DS. PMID: 15276354.
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    391. Biomaterial microarrays: rapid, microscale screening of polymer-cell interaction. Biomaterials. 2005 Aug; 26(23):4892-7. Anderson DG, Putnam D, Lavik EB, Mahmood TA, Langer R. PMID: 15763269.
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    392. Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res. 2004 Nov 01; 64(21):7668-72. Farokhzad OC, Jon S, Khademhosseini A, Tran TN, Lavan DA, Langer R. PMID: 15520166.
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    393. A polymer library approach to suicide gene therapy for cancer. Proc Natl Acad Sci U S A. 2004 Nov 09; 101(45):16028-33. Anderson DG, Peng W, Akinc A, Hossain N, Kohn A, Padera R, Langer R, Sawicki JA. PMID: 15520369; PMCID: PMC528737.
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    394. Association of morning illumination and window covering with mood and sleep among post-menopausal women. Sleep Biol Rhythms. 2004 Oct; 2(3):174-183. Youngstedt SD, Leung A, Kripke DF, Langer RD. PMID: 25374475; PMCID: PMC4217703.
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    395. Materials science. Smart biomaterials. Science. 2004 Sep 24; 305(5692):1923-4. Anderson DG, Burdick JA, Langer R. PMID: 15448260.
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    396. pH-triggered microparticles for peptide vaccination. J Immunol. 2004 Aug 15; 173(4):2578-85. Haining WN, Anderson DG, Little SR, von Bergwelt-Baildon MS, Cardoso AA, Alves P, Kosmatopoulos K, Nadler LM, Langer R, Kohane DS, von Berwelt-Baildon MS. PMID: 15294974.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    397. Naps and circadian rhythms in postmenopausal women. J Gerontol A Biol Sci Med Sci. 2004 Aug; 59(8):844-8. Yoon IY, Kripke DF, Elliott JA, Langer RD. PMID: 15345736.
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    398. A novel polymeric chlorhexidine delivery device for the treatment of periodontal disease. Biomaterials. 2004 Aug; 25(17):3743-50. Yue IC, Poff J, Cortés ME, Sinisterra RD, Faris CB, Hildgen P, Langer R, Shastri VP. PMID: 15020150.
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    399. Tissue plasminogen activator antigen and D-dimer as markers for atherothrombotic risk among healthy postmenopausal women. Circulation. 2004 Jul 20; 110(3):292-300. Pradhan AD, LaCroix AZ, Langer RD, Trevisan M, Lewis CE, Hsia JA, Oberman A, Kotchen JM, Ridker PM. PMID: 15238458.
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    400. Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Proc Natl Acad Sci U S A. 2004 Jun 29; 101(26):9534-9. Little SR, Lynn DM, Ge Q, Anderson DG, Puram SV, Chen J, Eisen HN, Langer R. PMID: 15210954; PMCID: PMC470709.
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    401. Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells. Nat Biotechnol. 2004 Jul; 22(7):863-6. Anderson DG, Levenberg S, Langer R. PMID: 15195101.
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    402. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 2004 Apr 14; 291(14):1701-12. Anderson GL, Limacher M, Assaf AR, Bassford T, Beresford SA, Black H, Bonds D, Brunner R, Brzyski R, Caan B, Chlebowski R, Curb D, Gass M, Hays J, Heiss G, Hendrix S, Howard BV, Hsia J, Hubbell A, Jackson R, Johnson KC, Judd H, Kotchen JM, Kuller L, LaCroix AZ, Lane D, Langer RD, Lasser N, Lewis CE, Manson J, Margolis K, Ockene J, O'Sullivan MJ, Phillips L, Prentice RL, Ritenbaugh C, Robbins J, Rossouw JE, Sarto G, Stefanick ML, Van Horn L, Wactawski-Wende J, Wallace R, Wassertheil-Smoller S, Women's Health Initiative Steering Committee. PMID: 15082697.
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    403. Ethnicity, sleep, mood, and illumination in postmenopausal women. BMC Psychiatry. 2004 Apr 07; 4:8. Kripke DF, Jean-Louis G, Elliott JA, Klauber MR, Rex KM, Tuunainen A, Langer RD. PMID: 15070419; PMCID: PMC400740.
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    404. In vivo inflammatory and wound healing effects of gold electrode voltammetry for MEMS micro-reservoir drug delivery device. IEEE Trans Biomed Eng. 2004 Apr; 51(4):627-35. Voskerician G, Shawgo RS, Hiltner PA, Anderson JM, Cima MJ, Langer R. PMID: 15072217.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    405. Poly(beta-amino ester)s promote cellular uptake of heparin and cancer cell death. Chem Biol. 2004 Apr; 11(4):487-98. Berry D, Lynn DM, Sasisekharan R, Langer R. PMID: 15123243.
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    406. Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002 : Section 4: lessons from hormone replacement trials. Circulation. 2004 Feb 17; 109(6):e53-5. Waters DD, Gordon D, Rossouw JE, Cannon RO, Collins P, Herrington DM, Hsia J, Langer R, Mosca L, Ouyang P, Sopko G, Stefanick ML, National Heart, Lung and Blood Institute, American College of Cardiology Foundation. PMID: 14970126.
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    407. Estrogen plus progestin and the risk of peripheral arterial disease: the Women's Health Initiative. Circulation. 2004 Feb 10; 109(5):620-6. Hsia J, Criqui MH, Rodabough RJ, Langer RD, Resnick HE, Phillips LS, Allison M, Bonds DE, Masaki K, Caralis P, Kotchen JM, Women's Health Initiative Investigators. PMID: 14769684.
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    408. Enhancement of a human immunodeficiency virus env DNA vaccine using a novel polycationic nanoparticle formulation. Immunol Lett. 2003 Dec 15; 90(2-3):67-70. Locher CP, Putnam D, Langer R, Witt SA, Ashlock BM, Levy JA. PMID: 14687705.
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    409. Postmenopausal hormone therapy and migraine headache. J Womens Health (Larchmt). 2003 Dec; 12(10):1027-36. Misakian AL, Langer RD, Bensenor IM, Cook NR, Manson JE, Buring JE, Rexrode KM. PMID: 14709191.
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    410. Polyhistidine-PEG:DNA nanocomposites for gene delivery. Biomaterials. 2003 Nov; 24(24):4425-33. Putnam D, Zelikin AN, Izumrudov VA, Langer R. PMID: 12922153.
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    411. Advancing the field of drug delivery: taking aim at cancer. Cancer Cell. 2003 Nov; 4(5):337-41. Moses MA, Brem H, Langer R. PMID: 14667500.
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    412. Degradable poly(amino alcohol esters) as potential DNA vectors with low cytotoxicity. Biomacromolecules. 2003 Nov-Dec; 4(6):1759-62. Jon S, Anderson DG, Langer R. PMID: 14606906.
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    413. pH-triggered release of macromolecules from spray-dried polymethacrylate microparticles. Pharm Res. 2003 Oct; 20(10):1533-8. Kohane DS, Anderson DG, Yu C, Langer R. PMID: 14620503.
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    414. The Women's Health Initiative Observational Study: baseline characteristics of participants and reliability of baseline measures. Ann Epidemiol. 2003 Oct; 13(9 Suppl):S107-21. Langer RD, White E, Lewis CE, Kotchen JM, Hendrix SL, Trevisan M. PMID: 14575943.
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    415. Synthesis of poly(beta-amino ester)s optimized for highly effective gene delivery. Bioconjug Chem. 2003 Sep-Oct; 14(5):979-88. Akinc A, Anderson DG, Lynn DM, Langer R. PMID: 13129402.
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    416. Chronic venous disease in an ethnically diverse population: the San Diego Population Study. Am J Epidemiol. 2003 Sep 01; 158(5):448-56. Criqui MH, Jamosmos M, Fronek A, Denenberg JO, Langer RD, Bergan J, Golomb BA. PMID: 12936900; PMCID: PMC4285442.
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    417. Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery. Angew Chem Int Ed Engl. 2003 Jul 14; 42(27):3153-8. Anderson DG, Lynn DM, Langer R. PMID: 12866105.
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    418. Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres. Pain. 2003 Jul; 104(1-2):415-21. Kohane DS, Smith SE, Louis DN, Colombo G, Ghoroghchian P, Hunfeld NG, Berde CB, Langer R. PMID: 12855352.
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    419. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial. JAMA. 2003 Jun 25; 289(24):3243-53. Chlebowski RT, Hendrix SL, Langer RD, Stefanick ML, Gass M, Lane D, Rodabough RJ, Gilligan MA, Cyr MG, Thomson CA, Khandekar J, Petrovitch H, McTiernan A, WHI Investigators. PMID: 12824205.
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    420. Sex and time differences in the associations of non-high-density lipoprotein cholesterol versus other lipid and lipoprotein factors in the prediction of cardiovascular death (The Rancho Bernardo Study). Am J Cardiol. 2003 Jun 01; 91(11):1311-5. von Mühlen D, Langer RD, Barrett-Connor E. PMID: 12767422.
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    421. Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery. J Am Chem Soc. 2003 May 07; 125(18):5316-23. Akinc A, Lynn DM, Anderson DG, Langer R. PMID: 12720443.
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    422. Quantified duplex augmentation in healthy subjects and patients with venous disease: San Diego population study. J Vasc Surg. 2003 May; 37(5):1054-8. Fronek A, Denenberg JO, Criqui MH, Langer RD. PMID: 12756354.
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    423. Biocompatibility and biofouling of MEMS drug delivery devices. Biomaterials. 2003 May; 24(11):1959-67. Voskerician G, Shive MS, Shawgo RS, von Recum H, Anderson JM, Cima MJ, Langer R. PMID: 12615486.
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    424. Gene transfer of a human insulin-like growth factor I cDNA enhances tissue engineering of cartilage. Hum Gene Ther. 2002 Sep 01; 13(13):1621-30. Madry H, Padera R, Seidel J, Langer R, Freed LE, Trippel SB, Vunjak-Novakovic G. PMID: 12228017.
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    425. Lipid-sugar particles for intracranial drug delivery: safety and biocompatibility. Brain Res. 2002 Aug 16; 946(2):206-13. Kohane DS, Plesnila N, Thomas SS, Le D, Langer R, Moskowitz MA. PMID: 12137923.
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    426. Adipose tissue mass can be regulated through the vasculature. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10730-5. Rupnick MA, Panigrahy D, Zhang CY, Dallabrida SM, Lowell BB, Langer R, Folkman MJ. PMID: 12149466; PMCID: PMC125027.
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    427. Hormone replacement and the prevention of cardiovascular disease. Am J Cardiol. 2002 Jun 20; 89(12A):36E-46E; discussion 46E. Langer RD. PMID: 12084403.
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    428. Measuring the pH environment of DNA delivered using nonviral vectors: implications for lysosomal trafficking. Biotechnol Bioeng. 2002 Jun 05; 78(5):503-8. Akinc A, Langer R. PMID: 12115119.
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    429. Depression and endogenous melatonin in postmenopausal women. J Affect Disord. 2002 May; 69(1-3):149-58. Tuunainen A, Kripke DF, Elliott JA, Assmus JD, Rex KM, Klauber MR, Langer RD. PMID: 12103461.
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    430. Evening light exposure: implications for sleep and depression. J Am Geriatr Soc. 2002 Apr; 50(4):738-9. Wallace-Guy GM, Kripke DF, Jean-Louis G, Langer RD, Elliott JA, Tuunainen A. PMID: 11982677.
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    431. Stability of electrocardiographic classification pre- and postglucose challenge. Am J Epidemiol. 2002 Mar 15; 155(6):577-9. Langer RD, Knoke JD, Barrett-Connor E. PMID: 11882532.
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    432. Biocompatibility of lipid-protein-sugar particles containing bupivacaine in the epineurium. J Biomed Mater Res. 2002 Mar 05; 59(3):450-9. Kohane DS, Lipp M, Kinney RC, Anthony DC, Louis DN, Lotan N, Langer R. PMID: 11774302.
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    433. Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. Proc Natl Acad Sci U S A. 2002 Mar 05; 99(5):3024-9. Teng YD, Lavik EB, Qu X, Park KI, Ourednik J, Zurakowski D, Langer R, Snyder EY. PMID: 11867737; PMCID: PMC122466.
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    434. Given diabetes, is fat better than thin? Diabetes Care. 1997 Apr; 20(4):650-2. Ross C, Langer RD, Barrett-Connor E. PMID: 9096997.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    435. Exercise and Survival in the Very Old. Am J Geriatr Cardiol. 1994 Jul; 3(4):24-34. Langer RD, Klauber MR, Criqui MH, Barret-Connor EL. PMID: 11416312.
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