Charles Mosier

Title(s)	SRA 1, School of Pharmacy and Pharmaceutical Science
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions. ACS Chem Biol. 2021 09 17; 16(9):1628-1643. Yoon MC, Solania A, Jiang Z, Christy MP, Podvin S, Mosier C, Lietz CB, Ito G, Gerwick WH, Wolan DW, Hook G, O'Donoghue AJ, Hook V. PMID: 34416110.

View in: PubMed Mentions: Fields:
Bio Biochemistry Bio Biology
Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons. ACS Omega. 2021 May 25; 6(20):13033-13056. Podvin S, Jones A, Liu Q, Aulston B, Mosier C, Ames J, Winston C, Lietz CB, Jiang Z, O'Donoghue AJ, Ikezu T, Rissman RA, Yuan SH, Hook V. PMID: 34056454.

View in: PubMed Mentions:
Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders. Biochim Biophys Acta Proteins Proteom. 2020 08; 1868(8):140428. Hook V, Yoon M, Mosier C, Ito G, Podvin S, Head BP, Rissman R, O'Donoghue AJ, Hook G. PMID: 32305689.

View in: PubMed Mentions: 8 Fields:
Bio Biochemistry Bio Biophysics Mol Molecular Biology
Translation:Humans Animals Cells
Multiple clinical features of Huntington's disease correlate with mutant HTT gene CAG repeat lengths and neurodegeneration. J Neurol. 2019 Mar; 266(3):551-564. Podvin S, Reardon HT, Yin K, Mosier C, Hook V. PMID: 29956026.

View in: PubMed Mentions: 8 Fields:
Neu Neurology
Translation:Humans Cells
Phosphopeptidomics Reveals Differential Phosphorylation States and Novel SxE Phosphosite Motifs of Neuropeptides in Dense Core Secretory Vesicles. J Am Soc Mass Spectrom. 2018 05; 29(5):935-947. Lietz CB, Toneff T, Mosier C, Podvin S, O'Donoghue AJ, Hook V. PMID: 29556927.

View in: PubMed Mentions: 6 Fields:
Che Chemistry Techniques
Translation:Animals Cells
Beta-amyloid peptides undergo regulated co-secretion with neuropeptide and catecholamine neurotransmitters. Peptides. 2013 Aug; 46:126-35. Toneff T, Funkelstein L, Mosier C, Abagyan A, Ziegler M, Hook V, Toneff T, Funkelstein L, Mosier C, Abagyan A, Ziegler M, Hook V. PMID: 23747840; PMCID: PMC3842158.

View in: PubMed Mentions: 14 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Human cathepsin V protease participates in production of enkephalin and NPY neuropeptide neurotransmitters. J Biol Chem. 2012 May 04; 287(19):15232-41. Funkelstein L, Lu WD, Koch B, Mosier C, Toneff T, Taupenot L, O'Connor DT, Reinheckel T, Peters C, Hook V, Funkelstein L, Lu WD, Koch B, Mosier C, Toneff T, Taupenot L, O'Connor DT, Reinheckel T, Peters C, Hook V. PMID: 22393040; PMCID: PMC3346103.

View in: PubMed Mentions: 14 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Proteomics of dense core secretory vesicles reveal distinct protein categories for secretion of neuroeffectors for cell-cell communication. J Proteome Res. 2010 Oct 01; 9(10):5002-24. Wegrzyn JL, Bark SJ, Funkelstein L, Mosier C, Yap A, Kazemi-Esfarjani P, La Spada AR, Sigurdson C, O'Connor DT, Hook V, Wegrzyn JL, Bark SJ, Funkelstein L, Mosier C, Yap A, Kazemi-Esfarjani P, La Spada AR, Sigurdson C, O'Connor DT, Hook V. PMID: 20695487; PMCID: PMC2996463.

View in: PubMed Mentions: 26 Fields:
Bio Biochemistry
Translation:Animals Cells
Human pituitary contains dual cathepsin L and prohormone convertase processing pathway components involved in converting POMC into the peptide hormones ACTH, alpha-MSH, and beta-endorphin. Endocrine. 2009 Jun; 35(3):429-37. Hook V, Funkelstein L, Toneff T, Mosier C, Hwang SR, Hook V, Funkelstein L, Toneff T, Mosier C, Hwang SR. PMID: 19343278; PMCID: PMC2731682.

View in: PubMed Mentions: 10 Fields:
End Endocrinology
Translation:Humans
Major role of cathepsin L for producing the peptide hormones ACTH, beta-endorphin, and alpha-MSH, illustrated by protease gene knockout and expression. J Biol Chem. 2008 Dec 19; 283(51):35652-9. Funkelstein L, Toneff T, Mosier C, Hwang SR, Beuschlein F, Lichtenauer UD, Reinheckel T, Peters C, Hook V, Funkelstein L, Toneff T, Mosier C, Hwang SR, Beuschlein F, Lichtenauer UD, Reinheckel T, Peters C, Hook V. PMID: 18849346; PMCID: PMC2602888.

View in: PubMed Mentions: 32 Fields:
Bio Biochemistry
Translation:Animals Cells
Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion. J Biol Chem. 2007 Mar 30; 282(13):9556-9563. Hwang SR, Garza C, Mosier C, Toneff T, Wunderlich E, Goldsmith P, Hook V, Hwang SR, Garza C, Mosier C, Toneff T, Wunderlich E, Goldsmith P, Hook V. PMID: 17244622.

View in: PubMed Mentions: 26 Fields:
Bio Biochemistry
Translation:Animals Cells