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    Faik Tezcan

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentChemistry and Biochemistry
    Address9500 Gilman Drive #0356
    CA La Jolla 92093
    Phone858-534-4862
    vCardDownload vCard

      Collapse Research 
      Collapse Research Activities and Funding
      Mechanism of Energy Transduction and Substrate Activation in Biological Nitrogen
      NIH/NIGMS R01GM099813Aug 1, 2012 - Apr 30, 2017
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Bailey JB, Zhang L, Chiong JA, Ahn S, Tezcan F. Synthetic Modularity of Protein-Metal-Organic Frameworks. J Am Chem Soc. 2017 Jun 21; 139(24):8160-8166. PMID: 28590729.
        View in: PubMed
      2. Churchfield LA, George A, Tezcan F. Repurposing proteins for new bioinorganic functions. Essays Biochem. 2017 May 09; 61(2):245-258. PMID: 28487401.
        View in: PubMed
      3. Katz FE, Shi X, Owens CP, Joseph S, Tezcan F. Determination of NTPase activities from measurement of true inorganic phosphate in the presence of labile phosphate compounds. Anal Biochem. 2016 Dec 22. PMID: 28017740.
        View in: PubMed
      4. Churchfield LA, Medina-Morales A, Brodin JD, Perez A, Tezcan F. De Novo Design of an Allosteric Metalloprotein Assembly with Strained Disulfide Bonds. J Am Chem Soc. 2016 Oct 12; 138(40):13163-13166. PMID: 27649076.
        View in: PubMed
      5. Owens CP, Katz FE, Carter CH, Oswald VF, Tezcan F. Tyrosine-Coordinated P-Cluster in G. diazotrophicus Nitrogenase: Evidence for the Importance of O-Based Ligands in Conformationally Gated Electron Transfer. J Am Chem Soc. 2016 Aug 17; 138(32):10124-7. PMID: 27487256.
        View in: PubMed
      6. Bailey JB, Subramanian RH, Churchfield LA, Tezcan F. Metal-Directed Design of Supramolecular Protein Assemblies. Methods Enzymol. 2016; 580:223-50. PMID: 27586336.
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      7. Smith SJ, Radford RJ, Subramanian RH, Barnett BR, Figueroa JS, Tezcan F. Tunable Helicity, Stability and DNA-Binding Properties of Short Peptides with Hybrid Metal Coordination Motifs. Chem Sci. 2016 Aug 1; 7(8):5453-5461. PMID: 27800151.
        View in: PubMed
      8. Suzuki Y, Cardone G, Restrepo D, Zavattieri PD, Baker TS, Tezcan F. Self-assembly of coherently dynamic, auxetic, two-dimensional protein crystals. Nature. 2016 May 19; 533(7603):369-73. PMID: 27135928.
        View in: PubMed
      9. Owens CP, Katz FE, Carter CH, Luca MA, Tezcan F. Evidence for Functionally Relevant Encounter Complexes in Nitrogenase Catalysis. J Am Chem Soc. 2015 Oct 7; 137(39):12704-12. PMID: 26360912.
        View in: PubMed
      10. Sontz PA, Bailey JB, Ahn S, Tezcan F. A Metal Organic Framework with Spherical Protein Nodes: Rational Chemical Design of 3D Protein Crystals. J Am Chem Soc. 2015 Sep 16; 137(36):11598-601. PMID: 26305584.
        View in: PubMed
      11. Brodin JD, Smith SJ, Carr JR, Tezcan F. Designed, Helical Protein Nanotubes with Variable Diameters from a Single Building Block. J Am Chem Soc. 2015 Aug 26; 137(33):10468-71. PMID: 26256820.
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      12. Tezcan F, Kaiser JT, Howard JB, Rees DC. Structural evidence for asymmetrical nucleotide interactions in nitrogenase. J Am Chem Soc. 2015 Jan 14; 137(1):146-9. PMID: 25522159.
        View in: PubMed
      13. Song WJ, Tezcan F. A designed supramolecular protein assembly with in vivo enzymatic activity. Science. 2014 Dec 19; 346(6216):1525-8. PMID: 25525249.
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      14. Machan CW, Chabolla SA, Yin J, Gilson MK, Tezcan F, Kubiak CP. Supramolecular assembly promotes the electrocatalytic reduction of carbon dioxide by re(i) bipyridine catalysts at a lower overpotential. J Am Chem Soc. 2014 Oct 15; 136(41):14598-607. PMID: 25226161.
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      15. Song WJ, Sontz PA, Ambroggio XI, Tezcan F. Metals in protein-protein interfaces. Annu Rev Biophys. 2014 May 6; 43:409-31. PMID: 24773016.
        View in: PubMed
      16. Brodin JD, Carr JR, Sontz PA, Tezcan F. Exceptionally stable, redox-active supramolecular protein assemblies with emergent properties. Proc Natl Acad Sci U S A. 2014 Feb 25; 111(8):2897-902. PMID: 24516140.
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      17. Sontz PA, Song WJ, Tezcan F. Interfacial metal coordination in engineered protein and peptide assemblies. Curr Opin Chem Biol. 2014 Apr; 19:42-9. PMID: 24780278.
        View in: PubMed
      18. Smith SJ, Du K, Radford RJ, Tezcan F. Functional, metal-based crosslinkers for a-helix induction in short peptides. Chem Sci. 2013 Sep; 4(9):3740-3747. PMID: 24156013.
        View in: PubMed
      19. Medina-Morales A, Perez A, Brodin JD, Tezcan F. In vitro and cellular self-assembly of a Zn-binding protein cryptand via templated disulfide bonds. J Am Chem Soc. 2013 Aug 14; 135(32):12013-22. PMID: 23905754.
        View in: PubMed
      20. Huard DJ, Kane KM, Tezcan F. Re-engineering protein interfaces yields copper-inducible ferritin cage assembly. Nat Chem Biol. 2013 Mar; 9(3):169-76. PMID: 23340339.
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      21. Roth LE, Tezcan F. ATP-uncoupled, six-electron photoreduction of hydrogen cyanide to methane by the molybdenum-iron protein. J Am Chem Soc. 2012 May 23; 134(20):8416-9. PMID: 22564208.
        View in: PubMed
      22. Brodin JD, Ambroggio XI, Tang C, Parent KN, Baker TS, Tezcan F. Metal-directed, chemically tunable assembly of one-, two- and three-dimensional crystalline protein arrays. Nat Chem. 2012 May; 4(5):375-82. PMID: 22522257.
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      23. Salgado EN, Brodin JD, To MM, Tezcan F. Templated construction of a Zn-selective protein dimerization motif. Inorg Chem. 2011 Jul 4; 50(13):6323-9. PMID: 21648390.
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      24. Roth LE, Tezcan F. X-ray crystallography. Methods Mol Biol. 2011; 766:147-64. PMID: 21833866.
        View in: PubMed
      25. Roth LE, Nguyen JC, Tezcan F. ATP- and iron-protein-independent activation of nitrogenase catalysis by light. J Am Chem Soc. 2010 Oct 6; 132(39):13672-4. PMID: 20843032.
        View in: PubMed
      26. Ni TW, Tezcan F. Structural characterization of a microperoxidase inside a metal-directed protein cage. Angew Chem Int Ed Engl. 2010 Sep 17; 49(39):7014-8. PMID: 20721993.
        View in: PubMed
      27. Radford RJ, Lawrenz M, Nguyen PC, McCammon JA, Tezcan F. Porous protein frameworks with unsaturated metal centers in sterically encumbered coordination sites. Chem Commun (Camb). 2011 Jan 7; 47(1):313-5. PMID: 20740227.
        View in: PubMed
      28. Radford RJ, Nguyen PC, Tezcan F. Modular and versatile hybrid coordination motifs on alpha-helical protein surfaces. Inorg Chem. 2010 Aug 2; 49(15):7106-15. PMID: 20617830.
        View in: PubMed
      29. Brodin JD, Medina-Morales A, Ni T, Salgado EN, Ambroggio XI, Tezcan F. Evolution of metal selectivity in templated protein interfaces. J Am Chem Soc. 2010 Jun 30; 132(25):8610-7. PMID: 20515031.
        View in: PubMed
      30. Salgado EN, Radford RJ, Tezcan F. Metal-directed protein self-assembly. Acc Chem Res. 2010 May 18; 43(5):661-72. PMID: 20192262.
        View in: PubMed
      31. Radford RJ, Nguyen PC, Ditri TB, Figueroa JS, Tezcan F. Controlled protein dimerization through hybrid coordination motifs. Inorg Chem. 2010 May 3; 49(9):4362-9. PMID: 20377257.
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      32. Salgado EN, Ambroggio XI, Brodin JD, Lewis RA, Kuhlman B, Tezcan F. Metal templated design of protein interfaces. Proc Natl Acad Sci U S A. 2010 Feb 2; 107(5):1827-32. PMID: 20080561.
        View in: PubMed
      33. Radford RJ, Tezcan F. A superprotein triangle driven by nickel(II) coordination: exploiting non-natural metal ligands in protein self-assembly. J Am Chem Soc. 2009 Jul 8; 131(26):9136-7. PMID: 19527025.
        View in: PubMed
      34. Salgado EN, Lewis RA, Mossin S, Rheingold AL, Tezcan F. Control of protein oligomerization symmetry by metal coordination: C2 and C3 symmetrical assemblies through Cu(II) and Ni(II) coordination. Inorg Chem. 2009 Apr 6; 48(7):2726-8. PMID: 19267481.
        View in: PubMed
      35. Salgado EN, Lewis RA, Faraone-Mennella J, Tezcan F. Metal-mediated self-assembly of protein superstructures: influence of secondary interactions on protein oligomerization and aggregation. J Am Chem Soc. 2008 May 14; 130(19):6082-4. PMID: 18422313.
        View in: PubMed
      36. Salgado EN, Faraone-Mennella J, Tezcan F. Controlling protein-protein interactions through metal coordination: assembly of a 16-helix bundle protein. J Am Chem Soc. 2007 Nov 7; 129(44):13374-5. PMID: 17929927.
        View in: PubMed
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