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Timothy Sears

Title(s)Postdoctoral Scholar, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. NeoPrecis: Enhancing Immunotherapy Response Prediction through Integration of Qualified Immunogenicity and Clonality-Aware Neoantigen Landscapes. bioRxiv. 2025 Jul 27. Lee KH, Sears TJ, Zanetti M, Carter H. PMID: 40777306; PMCID: PMC12330539.
      View in: PubMed   Mentions:
    2. MHC Hammer Decodes HLA Disruption in Tumors. Cancer Res. 2025 Feb 17; 85(4):642-643. Sears T, Carter H. PMID: 39636736.
      View in: PubMed   Mentions:
    3. Integrated Germline and Somatic Features Reveal Divergent Immune Pathways Driving Response to Immune Checkpoint Blockade. Cancer Immunol Res. 2024 Dec 03; 12(12):1780-1795. Sears TJ, Pagadala MS, Castro A, Lee KH, Kong J, Tanaka K, Lippman SM, Zanetti M, Carter H. PMID: 39255339; PMCID: PMC11612627.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    4. Genetic association and machine learning improves discovery and prediction of type 1 diabetes. medRxiv. 2024 Aug 02. McGrail C, Sears TJ, Kudtarkar P, Carter H, Gaulton K. PMID: 39132494; PMCID: PMC11312647.
      View in: PubMed   Mentions:
    5. Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy. Nat Cancer. 2024 04; 5(4):642-658. Subramanian A, Nemat-Gorgani N, Ellis-Caleo TJ, van IJzendoorn DGP, Sears TJ, Somani A, Luca BA, Zhou MY, Bradic M, Torres IA, Oladipo E, New C, Kenney DE, Avedian RS, Steffner RJ, Binkley MS, Mohler DG, Tap WD, D'Angelo SP, van de Rijn M, Ganjoo KN, Bui NQ, Charville GW, Newman AM, Moding EJ. PMID: 38429415; PMCID: PMC11058033.
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    6. Integrated germline and somatic features reveal divergent immune pathways driving ICB response. bioRxiv. 2024 Jan 15. Sears T, Pagadala M, Castro A, Lee KH, Kong J, Tanaka K, Lippman S, Zanetti M, Carter H. PMID: 38293085; PMCID: PMC10827124.
      View in: PubMed   Mentions:
    7. Application of a Machine Learning Algorithm in Prediction of Abusive Head Trauma in Children. J Pediatr Surg. 2024 Jan; 59(1):80-85. Jadhav P, Sears T, Floan G, Joskowitz K, Nienow S, Cruz S, David M, de Cos V, Choi P, Ignacio RC. PMID: 37858394.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Characterizing the role of Phlda3 in the development of acute toxicity and malignant transformation of hematopoietic cells induced by total-body irradiation in mice. Sci Rep. 2023 08 09; 13(1):12916. Hasapis S, Caraballo I, Sears TJ, Brock KD, Cart JB, Moding EJ, Lee CL. PMID: 37558703; PMCID: PMC10412554.
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    9. Monitoring Sarcoma Response to Immune Checkpoint Inhibition and Local Cryotherapy with Circulating Tumor DNA Analysis. Clin Cancer Res. 2023 07 14; 29(14):2612-2620. Bui NQ, Nemat-Gorgani N, Subramanian A, Torres IA, Lohman M, Sears TJ, van de Rijn M, Charville GW, Becker HC, Wang DS, Hwang GL, Ganjoo KN, Moding EJ. PMID: 37130154.
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    10. Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response. Nat Commun. 2023 05 12; 14(1):2744. Pagadala M, Sears TJ, Wu VH, Pérez-Guijarro E, Kim H, Castro A, Talwar JV, Gonzalez-Colin C, Cao S, Schmiedel BJ, Goudarzi S, Kirani D, Au J, Zhang T, Landi T, Salem RM, Morris GP, Harismendy O, Patel SP, Alexandrov LB, Mesirov JP, Zanetti M, Day CP, Fan CC, Thompson WK, Merlino G, Gutkind JS, Vijayanand P, Carter H. PMID: 37173324; PMCID: PMC10182072.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    11. Differential regulation of TNFα and IL-6 expression contributes to immune evasion in prostate cancer. J Transl Med. 2022 11 12; 20(1):527. Deichaite I, Sears TJ, Sutton L, Rebibo D, Morgan K, Nelson T, Rose B, Tamayo P, Ferrara N, Asimakopoulos F, Carter H. PMID: 36371231; PMCID: PMC9652804.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    12. Germline genetic biomarkers to stratify patients for personalized radiation treatment. J Transl Med. 2022 08 12; 20(1):360. Deichaite I, Hopper A, Krockenberger L, Sears TJ, Sutton L, Ray X, Sharabi A, Navon A, Sanghvi P, Carter H, Moiseenko V. PMID: 35962345; PMCID: PMC9373374.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
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