Sara Browne

Title(s)Clinical Professor, Medicine
SchoolHealth Sciences
vCardDownload vCard

    Collapse Overview 
    Collapse Overview
    Sara H. Browne, M.D. is an Associate Professor of Clinical Medicine in the Department of Medicine, Division of Infectious Diseases, at the University of California, San Diego (UCSD). Dr. Browne received her undergraduate education at the University of Cape Town, RSA and her medical degree from the Oxford University School of Medicine. She has a master of public health from the Harvard University School of Public Health, where she was a Fulbright Scholar. She completed her license in the United Kingdom at the John Radcliffe Hospital, Oxford, UK. She did her residency in Internal Medicine at Stanford University Medical Center, where subsequently completed a Clinical Pharmacology Fellowship at Stanford University and an Infectious Diseases Fellowship at UCSD.

    Since joining the UCSD faculty in 2006, Dr. Browne’s main focus has been Global Health and more recently Mobile Health. She has partnered with 3 institutions in South Africa (Stellenbosch University in the Western Cape and Rhodes University, Walter Sisulu University in the Eastern Cape) to support the development of skilled medically trained research faculty locally to better address clinical research questions crucial to the combat and treatment of the HIV/TB epidemics in Southern Africa. She has successfully mentored South African medical faculty in the design and development of three NIH-funded international HIV research projects in the areas of ART adherence, metabolic side effects in ART and transmitted HIV resistance. Research from these partnerships continue to yield both vital clinical data and clinical tools to implement in the field.

    Dr. Browne currently conducts translational research and clinical trials to analyze and support patient medication adherence and promote medication literacy in the treatment of HIV/AIDS, TB, and chronic diseases. She seeks to provide new paradigms of healthcare delivery especially in the arena of patient self-management with the use of novel mobile health (mHealth) technologies. Her collaborators include. In collaboration with Proteus Digital Health., who have developed an ingestible event marker that is able to capture oral ingestion medication, Dr. Browne is investigating the efficacy of mHealth sensor technology to monitor treatment of Mycobacterium tuberculosis. She is an Alliance Healthcare Foundation Innovation Award recipient for this work.

    Dr. Browne is the Principal Investigator in NIH R01 funded research into the use of ingestion sensor technology in the treatment and prevention of HIV infection. She is also funded to preform clinical trials on cell phone based remote vital sign monitoring.

    Collapse Research 
    Collapse Research Activities and Funding
    The Vital Case System for Remote Monitoring Multiple Vital Signs Simultaneously on Cell Phones
    NIH/NIMH R01MH110057 S3&4Jan 10, 2018 - Dec 31, 2020
    Role: Principal Investigator
    A Novel Wireless Ingestible Sensor System for Measurement of Medication Adherence in HIV Treatment and Prevention
    NIH/NIMH R01MH110057Sep 20, 2015 - Jul 31, 2020
    Role: Principal Investigator
    Screening for Atherosclerotic Vascular Disease in HIV-Infected Children
    NIH R01 HD083042-01May 5, 2015 - Apr 2, 2020
    Role: Principal Investigator
    Salmonella-induced Cytopathology in Human Macrophages
    NIH/NIAID K08AI062758May 15, 2005 - Apr 30, 2011
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Browne SH, Barford K, Ramela T, Dowse R. The impact of illustrated side effect information on understanding and sustained retention of antiretroviral side effect knowledge. Res Social Adm Pharm. 2019 Apr; 15(4):469-473. PMID: 29803539.
      View in: PubMed
    2. Browne SH, Peloquin C, Santillo F, Haubrich R, Muttera L, Moser K, Savage GM, Benson CA, Blaschke TF. Digitizing Medicines for Remote Capture of Oral Medication Adherence Using Co-encapsulation. Clin Pharmacol Ther. 2018 Mar; 103(3):502-510. PMID: 28597911.
      View in: PubMed
    3. Browne SH, Diaz-Perez JA, Preziosi M, King CC, Jones GA, Jain S, Sun X, Reid EG, VandenBerg S, Wang HY. mTOR activity in AIDS-related diffuse large B-cell lymphoma. PLoS One. 2017; 12(2):e0170771. PMID: 28192480.
      View in: PubMed
    4. Innes S, Abdullah KL, Haubrich R, Cotton MF, Browne SH. High Prevalence of Dyslipidemia and Insulin Resistance in HIV-infected Prepubertal African Children on Antiretroviral Therapy. Pediatr Infect Dis J. 2016 Jan; 35(1):e1-7. PMID: 26421804.
      View in: PubMed
    5. Browne SH, Behzadi Y, Littlewort G. Let Visuals Tell the Story: Medication Adherence in Patients with Type II Diabetes Captured by a Novel Ingestion Sensor Platform. JMIR Mhealth Uhealth. 2015 Dec 31; 3(4):e108. PMID: 26721413; PMCID: PMC4713908.
    6. Dowse R, Barford K, Browne SH. Simple, illustrated medicines information improves ARV knowledge and patient self-efficacy in limited literacy South African HIV patients. AIDS Care. 2014; 26(11):1400-6. PMID: 24975116.
      View in: PubMed
    7. Innes S, Schulte-Kemna E, Cotton MF, Zöllner EW, Haubrich R, Klinker H, Sun X, Jain S, Edson C, van Niekerk M, Innes ER, Rabie H, Browne SH. Biceps skin-fold thickness may detect and predict early lipoatrophy in HIV-infected children. Pediatr Infect Dis J. 2013 Jun; 32(6):e254-62. PMID: 23249919; PMCID: PMC4000309.
    8. Browne SH. Editorial commentary: dialing for doses: enhancing community-based adherence support with mobile technologies. Clin Infect Dis. 2013 May; 56(9):1327-9. PMID: 23249610.
      View in: PubMed
    9. Innes S, Cotton MF, Haubrich R, Conradie MM, van Niekerk M, Edson C, Rabie H, Jain S, Sun X, Zöllner EW, Hough S, Browne SH. High prevalence of lipoatrophy in pre-pubertal South African children on antiretroviral therapy: a cross-sectional study. BMC Pediatr. 2012 Nov 23; 12:183. PMID: 23176441; PMCID: PMC3584923.
    10. Preziosi MJ, Kandel SM, Guiney DG, Browne SH. Microbiological analysis of nontyphoidal Salmonella strains causing distinct syndromes of bacteremia or enteritis in HIV/AIDS patients in San Diego, California. J Clin Microbiol. 2012 Nov; 50(11):3598-603. PMID: 22933605; PMCID: PMC3486235.
    11. Dowse R, Ramela T, Browne SH. An illustrated leaflet containing antiretroviral information targeted for low-literate readers: development and evaluation. Patient Educ Couns. 2011 Dec; 85(3):508-15. PMID: 21306856.
      View in: PubMed
    12. van Sorge NM, Zialcita PA, Browne SH, Quach D, Guiney DG, Doran KS. Penetration and activation of brain endothelium by Salmonella enterica serovar Typhimurium. J Infect Dis. 2011 Feb 01; 203(3):401-5. PMID: 21186258; PMCID: PMC3071103.
    13. Browne SH, Hasegawa P, Okamoto S, Fierer J, Guiney DG. Identification of Salmonella SPI-2 secretion system components required for SpvB-mediated cytotoxicity in macrophages and virulence in mice. FEMS Immunol Med Microbiol. 2008 Mar; 52(2):194-201. PMID: 18248436.
      View in: PubMed
    14. Browne SH, Lesnick ML, Guiney DG. Genetic requirements for salmonella-induced cytopathology in human monocyte-derived macrophages. Infect Immun. 2002 Dec; 70(12):7126-35. PMID: 12438395; PMCID: PMC133012.
    15. Vinazzer H. [On the effect of anticoagulants]. Wien Med Wochenschr. 1965 Jul 17; 115(29):606-8. PMID: 5836848.
      View in: PubMed