Randolph Hampton

Title(s)Professor, Cell and Developmental Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Pathways in Biological Sciences Training Program
    NIH T32GM133351Jul 1, 2020 - Jun 30, 2025
    Role: Principal Investigator
    FASEB SRC on Ubiquitin and Cellular Regulation
    NIH R13CA168247Jul 27, 2012 - May 31, 2013
    Role: Principal Investigator
    Ubr1: A Protein Quality Control E3 Ubiquitin Ligase
    NIH R01GM092748Sep 30, 2011 - May 31, 2016
    Role: Principal Investigator
    Mallosteric Regulation of the Sterol Pathway
    NIH R01DK051996Jan 1, 1997 - Jul 31, 2025
    Role: Principal Investigator
    Protein degradation and cholesterol regulation
    NIH R37DK051996Jan 1, 1997 - Jan 31, 2021
    Role: Principal Investigator
    IVEM and Image Analysis Resource
    NIH P41RR004050Dec 12, 1988 - Mar 31, 2014
    Role: Co-Investigator
    Cell and Molecular Genetics Training Program
    NIH T32GM007240Jul 1, 1975 - Jun 30, 2021
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Exploring the "misfolding problem" by systematic discovery and analysis of functional-but-degraded proteins. Mol Biol Cell. 2023 Dec 01; 34(13):ar125. Flagg MP, Lam B, Lam DK, Le TM, Kao A, Slaiwa YI, Hampton RY. PMID: 37729018; PMCID: PMC10848938.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    2. Inner-nuclear-membrane-associated degradation employs Dfm1-independent retrotranslocation and alleviates misfolded transmembrane-protein toxicity. Mol Biol Cell. 2021 04 01; 32(7):521-537. Flagg MP, Wangeline MA, Holland SR, Duttke SH, Benner C, Neal S, Hampton RY. PMID: 33566711; PMCID: PMC8101470.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    3. An autonomous, but INSIG-modulated, role for the sterol sensing domain in mallostery-regulated ERAD of yeast HMG-CoA reductase. J Biol Chem. 2021 Jan-Jun; 296:100063. Wangeline MA, Hampton RY. PMID: 33184059; PMCID: PMC7948459.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    4. Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control. Mol Biol Cell. 2020 11 15; 31(24):2669-2686. Singh A, Vashistha N, Heck J, Tang X, Wipf P, Brodsky JL, Hampton RY. PMID: 32966159; PMCID: PMC7927186.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    5. HRD Complex Self-Remodeling Enables a Novel Route of Membrane Protein Retrotranslocation. iScience. 2020 Aug 21; 23(9):101493. Neal S, Syau D, Nejatfard A, Nadeau S, Hampton RY. PMID: 32891886; PMCID: PMC7481253.
      View in: PubMed   Mentions: 12  
    6. Integrating after CEN Excision (ICE) Plasmids: Combining the ease of yeast recombination cloning with the stability of genomic integration. Yeast. 2019 10; 36(10):593-605. Flagg MP, Kao A, Hampton RY. PMID: 31074531.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    7. Assays for protein retrotranslocation in ERAD. Methods Enzymol. 2019; 619:1-26. Neal S, Duttke SH, Hampton RY. PMID: 30910017; PMCID: PMC10802991.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    8. "Mallostery"-ligand-dependent protein misfolding enables physiological regulation by ERAD. J Biol Chem. 2018 09 21; 293(38):14937-14950. Wangeline MA, Hampton RY. PMID: 30018140; PMCID: PMC6153289.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    9. The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Mol Cell. 2018 03 01; 69(5):915. Neal S, Jaeger PA, Duttke SH, Benner C, Glass CK, Ideker T, Hampton RY. PMID: 29499140.
      View in: PubMed   Mentions: 12     Fields:    
    10. Systematic Gene-to-Phenotype Arrays: A High-Throughput Technique for Molecular Phenotyping. Mol Cell. 2018 01 18; 69(2):321-333.e3. Jaeger PA, Ornelas L, McElfresh C, Wong LR, Hampton RY, Ideker T. PMID: 29351850; PMCID: PMC5777277.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    11. The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Mol Cell. 2018 01 18; 69(2):306-320.e4. Neal S, Jaeger PA, Duttke SH, Benner C, K Glass C, Ideker T, Hampton RY. PMID: 29351849; PMCID: PMC6049073.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    12. Proteostatic Tactics in the Strategy of Sterol Regulation. Annu Rev Cell Dev Biol. 2017 10 06; 33:467-489. Wangeline MA, Vashistha N, Hampton RY. PMID: 28992438; PMCID: PMC6037418.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    13. New developments for protein quality control. Science. 2017 08 04; 357(6350):450-451. Hampton RY, Dargemont C. PMID: 28774913.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    14. A Cdc48 "Retrochaperone" Function Is Required for the Solubility of Retrotranslocated, Integral Membrane Endoplasmic Reticulum-associated Degradation (ERAD-M) Substrates. J Biol Chem. 2017 02 24; 292(8):3112-3128. Neal S, Mak R, Bennett EJ, Hampton R. PMID: 28077573; PMCID: PMC5336148.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    15. Control of the innate immune response by the mevalonate pathway. Nat Immunol. 2016 08; 17(8):922-9. Akula MK, Shi M, Jiang Z, Foster CE, Miao D, Li AS, Zhang X, Gavin RM, Forde SD, Germain G, Carpenter S, Rosadini CV, Gritsman K, Chae JJ, Hampton R, Silverman N, Gravallese EM, Kagan JC, Fitzgerald KA, Kastner DL, Golenbock DT, Bergo MO, Wang D. PMID: 27270400; PMCID: PMC4955724.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCells
    16. Direct and essential function for Hrd3 in ER-associated degradation. Proc Natl Acad Sci U S A. 2016 May 24; 113(21):5934-9. Vashistha N, Neal SE, Singh A, Carroll SM, Hampton RY. PMID: 27170191; PMCID: PMC4889393.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    17. The Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal Proteins. Mol Cell. 2015 Jul 02; 59(1):35-49. Higgins R, Gendron JM, Rising L, Mak R, Webb K, Kaiser SE, Zuzow N, Riviere P, Yang B, Fenech E, Tang X, Lindsay SA, Christianson JC, Hampton RY, Wasserman SA, Bennett EJ. PMID: 26051182; PMCID: PMC4491043.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    18. Insulin-induced gene protein (INSIG)-dependent sterol regulation of Hmg2 endoplasmic reticulum-associated degradation (ERAD) in yeast. J Biol Chem. 2013 Mar 22; 288(12):8519-8530. Theesfeld CL, Hampton RY. PMID: 23306196; PMCID: PMC3605666.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    19. Finding the will and the way of ERAD substrate retrotranslocation. Curr Opin Cell Biol. 2012 Aug; 24(4):460-6. Hampton RY, Sommer T. PMID: 22854296.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    20. Cytosolic entry of Shiga-like toxin a chain from the yeast endoplasmic reticulum requires catalytically active Hrd1p. PLoS One. 2012; 7(7):e41119. Li S, Spooner RA, Hampton RY, Lord JM, Roberts LM. PMID: 22829918; PMCID: PMC3400632.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    21. The sterol-sensing domain (SSD) directly mediates signal-regulated endoplasmic reticulum-associated degradation (ERAD) of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase isozyme Hmg2. J Biol Chem. 2011 Jul 29; 286(30):26298-307. Theesfeld CL, Pourmand D, Davis T, Garza RM, Hampton RY. PMID: 21628456; PMCID: PMC3143592.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    22. San1-mediated quality control: substrate recognition "sans" chaperones. Mol Cell. 2011 Jan 07; 41(1):2-3. Hampton RY. PMID: 21211716.
      View in: PubMed   Mentions: 5     Fields:    
    23. Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1. Proc Natl Acad Sci U S A. 2010 Jan 19; 107(3):1106-11. Heck JW, Cheung SK, Hampton RY. PMID: 20080635; PMCID: PMC2824284.
      View in: PubMed   Mentions: 157     Fields:    Translation:AnimalsCells
    24. Geranylgeranyl pyrophosphate is a potent regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA reductase degradation in yeast. J Biol Chem. 2009 Dec 18; 284(51):35368-80. Garza RM, Tran PN, Hampton RY. PMID: 19776008; PMCID: PMC2790966.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    25. Usa1p is required for optimal function and regulation of the Hrd1p endoplasmic reticulum-associated degradation ubiquitin ligase. J Biol Chem. 2010 Feb 19; 285(8):5146-56. Carroll SM, Hampton RY. PMID: 19940128; PMCID: PMC2820741.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    26. Misfolded membrane proteins are specifically recognized by the transmembrane domain of the Hrd1p ubiquitin ligase. Mol Cell. 2009 Apr 24; 34(2):212-22. Sato BK, Schulz D, Do PH, Hampton RY. PMID: 19394298; PMCID: PMC2710143.
      View in: PubMed   Mentions: 125     Fields:    Translation:AnimalsCells
    27. Protein quality control as a strategy for cellular regulation: lessons from ubiquitin-mediated regulation of the sterol pathway. Chem Rev. 2009 Apr; 109(4):1561-74. Hampton RY, Garza RM. PMID: 19243134; PMCID: PMC8530524.
      View in: PubMed   Mentions: 55     Fields:    Translation:Cells
    28. In vitro analysis of Hrd1p-mediated retrotranslocation of its multispanning membrane substrate 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase. J Biol Chem. 2009 May 29; 284(22):14710-22. Garza RM, Sato BK, Hampton RY. PMID: 19324879; PMCID: PMC2685653.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    29. A cholesterol toggle switch. Cell Metab. 2008 Dec; 8(6):451-3. Hampton RY. PMID: 19041760.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    30. Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae. Mol Biol Cell. 2008 Oct; 19(10):4506-20. Federovitch CM, Jones YZ, Tong AH, Boone C, Prinz WA, Hampton RY. PMID: 18667535; PMCID: PMC2555956.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    31. Cue1p is an activator of Ubc7p E2 activity in vitro and in vivo. J Biol Chem. 2008 May 09; 283(19):12797-810. Bazirgan OA, Hampton RY. PMID: 18321851; PMCID: PMC2442330.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    32. Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase. J Biol Chem. 2007 Nov 16; 282(46):33776-33787. Chen D, Gould C, Garza R, Gao T, Hampton RY, Newton AC. PMID: 17893151.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    33. Determinants of RING-E2 fidelity for Hrd1p, a membrane-anchored ubiquitin ligase. J Biol Chem. 2006 Dec 22; 281(51):38989-9001. Bazirgan OA, Garza RM, Hampton RY. PMID: 17035235.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    34. Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis. Yeast. 2006 Oct-Nov; 23(14-15):1053-64. Sato BK, Hampton RY. PMID: 17083136.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    35. INSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteins. EMBO J. 2005 Nov 16; 24(22):3917-26. Flury I, Garza R, Shearer A, Rosen J, Cronin S, Hampton RY. PMID: 16270032; PMCID: PMC1283954.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    36. The dynamic ER: experimental approaches and current questions. Curr Opin Cell Biol. 2005 Aug; 17(4):409-14. Federovitch CM, Ron D, Hampton RY. PMID: 15975777.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    37. Cell biology: sterol sensor comes up for air. Nature. 2005 May 05; 435(7038):37-8. Garza RM, Hampton RY. PMID: 15875007.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    38. Cdc48-Ufd2-Rad23: the road less ubiquitinated? Nat Cell Biol. 2005 Mar; 7(3):207-9. Bazirgan OA, Hampton RY. PMID: 15738968.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    39. Lipid-mediated, reversible misfolding of a sterol-sensing domain protein. EMBO J. 2005 Jan 12; 24(1):149-59. Shearer AG, Hampton RY. PMID: 15635451; PMCID: PMC544911.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    40. Fusion-based strategies to identify genes involved in degradation of a specific substrate. Methods Enzymol. 2005; 399:310-23. Hampton RY. PMID: 16338365.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    41. Membrane biogenesis and the unfolded protein response. J Cell Biol. 2004 Oct 11; 167(1):23-5. Ron D, Hampton RY. PMID: 15479733; PMCID: PMC2172515.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    42. Structural control of endoplasmic reticulum-associated degradation: effect of chemical chaperones on 3-hydroxy-3-methylglutaryl-CoA reductase. J Biol Chem. 2004 Jan 02; 279(1):188-96. Shearer AG, Hampton RY. PMID: 14570925.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    43. IRE1: a role in UPREgulation of ER degradation. Dev Cell. 2003 Feb; 4(2):144-6. Hampton RY. PMID: 12586055.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    44. ER-associated degradation in protein quality control and cellular regulation. Curr Opin Cell Biol. 2002 Aug; 14(4):476-82. Hampton RY. PMID: 12383799.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansAnimalsCells
    45. Cod1p/Spf1p is a P-type ATPase involved in ER function and Ca2+ homeostasis. J Cell Biol. 2002 Jun 10; 157(6):1017-28. Cronin SR, Rao R, Hampton RY. PMID: 12058017; PMCID: PMC2174042.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    46. Cdc48-Ufd1-Npl4: stuck in the middle with Ub. Curr Biol. 2002 May 14; 12(10):R366-71. Bays NW, Hampton RY. PMID: 12015140.
      View in: PubMed   Mentions: 64     Fields:    Translation:Cells
    47. Proteolysis and sterol regulation. Annu Rev Cell Dev Biol. 2002; 18:345-78. Hampton RY. PMID: 12142284.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    48. HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Mol Biol Cell. 2001 Dec; 12(12):4114-28. Bays NW, Wilhovsky SK, Goradia A, Hodgkiss-Harlow K, Hampton RY. PMID: 11739805; PMCID: PMC60780.
      View in: PubMed   Mentions: 129     Fields:    Translation:AnimalsCells
    49. In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation. Mol Cell Biol. 2001 Jul; 21(13):4276-91. Gardner RG, Shearer AG, Hampton RY. PMID: 11390656; PMCID: PMC87088.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    50. Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation. Nat Cell Biol. 2001 Jan; 3(1):24-9. Bays NW, Gardner RG, Seelig LP, Joazeiro CA, Hampton RY. PMID: 11146622.
      View in: PubMed   Mentions: 211     Fields:    Translation:AnimalsCells
    51. An oxysterol-derived positive signal for 3-hydroxy- 3-methylglutaryl-CoA reductase degradation in yeast. J Biol Chem. 2001 Mar 23; 276(12):8681-94. Gardner RG, Shan H, Matsuda SP, Hampton RY. PMID: 11134013.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    52. Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p. J Cell Biol. 2000 Oct 02; 151(1):69-82. Gardner RG, Swarbrick GM, Bays NW, Cronin SR, Wilhovsky S, Seelig L, Kim C, Hampton RY. PMID: 11018054; PMCID: PMC2189800.
      View in: PubMed   Mentions: 156     Fields:    Translation:Cells
    53. ER stress response: getting the UPR hand on misfolded proteins. Curr Biol. 2000 Jul 13; 10(14):R518-21. Hampton RY. PMID: 10898996.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    54. HRD gene dependence of endoplasmic reticulum-associated degradation. Mol Biol Cell. 2000 May; 11(5):1697-708. Wilhovsky S, Gardner R, Hampton R. PMID: 10793145; PMCID: PMC14877.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    55. Cholesterol homeostasis: ESCAPe from the ER. Curr Biol. 2000 Apr 20; 10(8):R298-301. Hampton RY. PMID: 10801406.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    56. Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p. J Cell Biol. 2000 Mar 06; 148(5):915-24. Cronin SR, Khoury A, Ferry DK, Hampton RY. PMID: 10704442; PMCID: PMC2174543.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    57. A 'distributed degron' allows regulated entry into the ER degradation pathway. EMBO J. 1999 Nov 01; 18(21):5994-6004. Gardner RG, Hampton RY. PMID: 10545111; PMCID: PMC1171665.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    58. A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes. J Biol Chem. 1999 Oct 29; 274(44):31671-8. Gardner RG, Hampton RY. PMID: 10531376.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    59. Measuring protein degradation with green fluorescent protein. Methods Enzymol. 1999; 302:58-73. Cronin SR, Hampton RY. PMID: 12876763.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    60. Sequence determinants for regulated degradation of yeast 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein. Mol Biol Cell. 1998 Sep; 9(9):2611-26. Gardner R, Cronin S, Leader B, Rine J, Hampton R, Leder B. PMID: 9725915; PMCID: PMC25534.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    61. Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends Biochem Sci. 1998 Jul; 23(7):244-5. Finley D, Tanaka K, Mann C, Feldmann H, Hochstrasser M, Vierstra R, Johnston S, Hampton R, Haber J, Mccusker J, Silver P, Frontali L, Thorsness P, Varshavsky A, Byers B, Madura K, Reed SI, Wolf D, Jentsch S, Sommer T, Baumeister W, Goldberg A, Fried V, Rubin DM, Toh-e A, et al. PMID: 9697412.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    62. Genetic analysis of hydroxymethylglutaryl-coenzyme A reductase regulated degradation. Curr Opin Lipidol. 1998 Apr; 9(2):93-7. Hampton RY. PMID: 9559264.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    63. Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase. Proc Natl Acad Sci U S A. 1997 Nov 25; 94(24):12944-8. Hampton RY, Bhakta H. PMID: 9371780; PMCID: PMC24243.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    64. Effects of overproduction of the catalytic domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase on squalene synthesis in Saccharomyces cerevisiae. Appl Environ Microbiol. 1997 Sep; 63(9):3341-4. Donald KA, Hampton RY, Fritz IB. PMID: 9292983; PMCID: PMC168639.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    65. Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein. Mol Biol Cell. 1996 Dec; 7(12):2029-44. Hampton RY, Gardner RG, Rine J. PMID: 8970163; PMCID: PMC276048.
      View in: PubMed   Mentions: 238     Fields:    Translation:Cells
    66. The biology of HMG-CoA reductase: the pros of contra-regulation. Trends Biochem Sci. 1996 Apr; 21(4):140-5. Hampton R, Dimster-Denk D, Rine J. PMID: 8701471.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    67. In vivo examination of membrane protein localization and degradation with green fluorescent protein. Proc Natl Acad Sci U S A. 1996 Jan 23; 93(2):828-33. Hampton RY, Koning A, Wright R, Rine J. PMID: 8570643; PMCID: PMC40142.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    68. Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast. J Cell Biol. 1994 Apr; 125(2):299-312. Hampton RY, Rine J. PMID: 8163547; PMCID: PMC2120026.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    69. Lipid A 4'-kinase from Escherichia coli: enzyme assay and preparation of 4'-32P-labeled probes of high specific radioactivity. Methods Enzymol. 1992; 209:466-75. Hampton RY, Raetz CR. PMID: 1323052.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    70. Recognition and plasma clearance of endotoxin by scavenger receptors. Nature. 1991 Jul 25; 352(6333):342-4. Hampton RY, Golenbock DT, Penman M, Krieger M, Raetz CR. PMID: 1852209.
      View in: PubMed   Mentions: 128     Fields:    Translation:AnimalsCells
    71. Effects of changes in osmolality on the stability and function of cultured chromaffin cells and the possible role of osmotic forces in exocytosis. J Cell Biol. 1983 Apr; 96(4):1082-8. Hampton RY, Holz RW. PMID: 6833392; PMCID: PMC2112313.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
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