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Fred Levine

Title(s)Recall Faculty, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    High-Throughput Screen for Beta-Cell Replication
    NIH/NINDS R21NS057001Sep 5, 2006 - Mar 31, 2008
    Role: Principal Investigator
    Small Molecular Regulation of Beta-Cell Differentiation
    NIH/NIDDK R01DK068754Jul 1, 2004 - Jun 30, 2006
    Role: Principal Investigator
    INHIBITION OF APOPTOSIS IN PANCREATIC BETA CELLS
    NIH/NIDDK R01DK055065Sep 30, 1998 - Sep 29, 2002
    Role: Principal Investigator
    Growth Versus Differentiation in Human Beta Cells
    NIH/NIDDK R01DK055283Sep 30, 1998 - Sep 29, 2002
    Role: Principal Investigator
    PANCREATIC CELL LINES--DEVELOPMENT AND CHARACTERIZATION
    NIH/NIDDK R55DK050171Sep 1, 1995 - Aug 31, 1997
    Role: Principal Investigator
    GENE EXPRESSION FROM RETROVIRAL VECTORS AND GENE THERAPY
    NIH/NIGMS F32GM013538Aug 1, 1990
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Efficient ß-cell regeneration by a combination of neogenesis and replication following ß-cell ablation and reversal of pancreatic duct ligation. Stem Cells. 2013 Nov; 31(11):2388-95. Hao E, Lee SH, Levine F. PMID: 23922239.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    2. HNF4a antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chem Biol. 2012 Jul 27; 19(7):806-18. Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, Higginbotham J, Cashman J, Freeze H, Itkin-Ansari P, Dawson MI, Schroeder F, Cang Y, Mercola M, Levine F. PMID: 22840769.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    3. Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen. J Biomol Screen. 2010 Jul; 15(6):663-70. Kiselyuk A, Farber-Katz S, Cohen T, Lee SH, Geron I, Azimi B, Heynen-Genel S, Singer O, Price J, Mercola M, Itkin-Ansari P, Levine F. PMID: 20547533.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    4. beta-cell Regeneration: neogenesis, replication or both? J Mol Med (Berl). 2008 Mar; 86(3):247-58. Levine F, Itkin-Ansari P. PMID: 17922102.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    5. HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion. Biochem Biophys Res Commun. 2007 Apr 06; 355(2):331-7. Ball AJ, Abrahamsson AE, Tyrberg B, Itkin-Ansari P, Levine F. PMID: 17300753.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    6. Cryopreservation by slow cooling with DMSO diminished production of Oct-4 pluripotency marker in human embryonic stem cells. Cryobiology. 2006 Oct; 53(2):194-205. Katkov II, Kim MS, Bajpai R, Altman YS, Mercola M, Loring JF, Terskikh AV, Snyder EY, Levine F. PMID: 16839540.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    7. Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas. Nat Med. 2006 Mar; 12(3):310-6. Hao E, Tyrberg B, Itkin-Ansari P, Lakey JR, Geron I, Monosov EZ, Barcova M, Mercola M, Levine F. PMID: 16491084.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    8. Telomere-independent cellular senescence in human fetal cardiomyocytes. Aging Cell. 2005 Feb; 4(1):21-30. Ball AJ, Levine F. PMID: 15659210.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    9. No pancreatic endocrine stem cells? N Engl J Med. 2004 Sep 02; 351(10):1024-6. Levine F, Mercola M. PMID: 15342812.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    10. Chronic treatment of mitochondrial disease patients with dichloroacetate. Mol Genet Metab. 2004 Sep-Oct; 83(1-2):138-49. Barshop BA, Naviaux RK, McGowan KA, Levine F, Nyhan WL, Loupis-Geller A, Haas RH. PMID: 15464428.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    11. Prediction of the glass transition temperature of water solutions: comparison of different models. Cryobiology. 2004 Aug; 49(1):62-82. Katkov II, Levine F. PMID: 15265717.
      View in: PubMed   Mentions: 7     Fields:    
    12. Sources of beta-cells for human cell-based therapies for diabetes. Cell Biochem Biophys. 2004; 40(3 Suppl):103-12. Itkin-Ansari P, Levine F. PMID: 15289647.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    13. Cell-based therapies for diabetes: progress towards a transplantable human beta cell line. Ann N Y Acad Sci. 2003 Nov; 1005:138-47. Itkin-Ansari P, Geron I, Hao E, Demeterco C, Tyrberg B, Levine F. PMID: 14679048.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    14. c-Myc controls proliferation versus differentiation in human pancreatic endocrine cells. J Clin Endocrinol Metab. 2002 Jul; 87(7):3475-85. Demeterco C, Itkin-Ansari P, Tyrberg B, Ford LP, Jarvis RA, Levine F. PMID: 12107268.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    15. Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes. BMC Endocr Disord. 2002 Apr 25; 2(1):2. Tyrberg B, Anachkov KA, Dib SA, Wang-Rodriguez J, Yoon KH, Levine F. PMID: 12003641.
      View in: PubMed   Mentions: 12     Fields:    
    16. Towards gene therapy of diabetes mellitus. Mol Med Today. 1999 Apr; 5(4):165-71. Levine F, Leibowitz G. PMID: 10203749.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
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