Esteban Moya Cespedes

Title(s)	Assistant Project Scientist, Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Biography

Education and Training

Pontificia Universidad Católica, Chile	Ph.D.	2014	Physiology
Pontificia Universidad Católica, Chile	M.S.	2010	Biological Sciences
Pontificia Universidad Católica, Chile	Biochemistry	2008	Biochemistry

Awards and Honors

Journal of Histochemistry and Cytochemistry, Volumen 66, Issue 10, October.	2018	Selected Cover
Center for Physiological Genomics of Low oxygen	2017	Best Poster Award
American Physiological Society	2016	APS-TPS Joint Meeting Travel Award
Society for High Altitude and Medicine	2010	Young Latin American Researcher Award

Overview

Currently studying the consequences of sustained hypoxia exposure (low O2) on the neuroplasticity occurring in the neurons and glial cells of the brainstem areas that control the ventilation, as well as the changes in the ventilatory acclimatization to low O2 and high CO2 exposure in rodents.

Interests

Hypoxia, Control of Breathing, Neuroplasticity, High Altitude

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Effects of vagotomy on cardiovascular and heart rate variability alterations following chronic normobaric hypoxia in adult rabbits. Biol Res. 2018 Dec 20; 51(1):57. Alcayaga J, Del Rio R, Moya EA, Freire M, Iturriaga R. PMID: 30572940; PMCID: PMC6300919.

View in: PubMed Mentions: 3 Fields:
Bio Biology
Translation:Animals
AMP-activated Protein Kinase Phosphorylation of Angiotensin-Converting Enzyme 2 in Endothelium Mitigates Pulmonary Hypertension. Am J Respir Crit Care Med. 2018 08 15; 198(4):509-520. Zhang J, Dong J, Martin M, He M, Gongol B, Marin TL, Chen L, Shi X, Yin Y, Shang F, Wu Y, Huang HY, Zhang J, Zhang Y, Kang J, Moya EA, Huang HD, Powell FL, Chen Z, Thistlethwaite PA, Yuan ZY, Shyy JY. PMID: 29570986; PMCID: PMC6118028.

View in: PubMed Mentions: 111 Fields:
Cri Critical Care Pul Pulmonary Medicine
Translation:Humans Animals
Serotonin and Adenosine G-protein Coupled Receptor Signaling for Ventilatory Acclimatization to Sustained Hypoxia. Front Physiol. 2018; 9:860. Moya EA, Powell FL. PMID: 30072908; PMCID: PMC6059110.

View in: PubMed Mentions:
Nitration of MnSOD in the Carotid Body and Adrenal Gland Induced by Chronic Intermittent Hypoxia. J Histochem Cytochem. 2018 10; 66(10):753-765. Moya EA, Arias P, Iturriaga R. PMID: 29775122; PMCID: PMC6158631.

View in: PubMed Mentions: 1 Fields:
His Histocytochemistry
Translation:Animals Cells
Transcriptomic analysis identifies a role of PI3K-Akt signalling in the responses of skeletal muscle to acute hypoxia in vivo. J Physiol. 2017 09 01; 595(17):5797-5813. Gan Z, Powell FL, Zambon AC, Buchholz KS, Fu Z, Ocorr K, Bodmer R, Moya EA, Stowe JC, Haddad GG, McCulloch AD. PMID: 28688178; PMCID: PMC5577531.

View in: PubMed Mentions: 4 Fields:
Phy Physiology
Translation:Animals Cells
Minocycline blocks glial cell activation and ventilatory acclimatization to hypoxia. J Neurophysiol. 2017 04 01; 117(4):1625-1635. Stokes JA, Arbogast TE, Moya EA, Fu Z, Powell FL. PMID: 28100653; PMCID: PMC5380779.

View in: PubMed Mentions: 17 Fields:
Neu Neurology Phy Physiology
Translation:Animals Cells
Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation. Oxid Med Cell Longev. 2016; 2016:9802136. Moya EA, Arias P, Varela C, Oyarce MP, Del Rio R, Iturriaga R. PMID: 26798430; PMCID: PMC4699095.

View in: PubMed Mentions: 13 Fields:
Cel Cell Biology Met Metabolism
Translation:Animals Cells
Arginase-endothelial nitric oxide synthase imbalance contributes to endothelial dysfunction during chronic intermittent hypoxia. J Hypertens. 2015 Mar; 33(3):515-24; discussion 524. Krause BJ, Del Rio R, Moya EA, Marquez-Gutierrez M, Casanello P, Iturriaga R. PMID: 25629363.

View in: PubMed Mentions: 15 Fields:
Vas Vascular Diseases
Translation:Animals
Inflammation and oxidative stress during intermittent hypoxia: the impact on chemoreception. Exp Physiol. 2015 Feb 01; 100(2):149-55. Iturriaga R, Moya EA, Del Rio R. PMID: 25523440.

View in: PubMed Mentions: 25 Fields:
Phy Physiology
Translation:Humans Animals Cells
Carotid body potentiation during chronic intermittent hypoxia: implication for hypertension. Front Physiol. 2014; 5:434. Del Rio R, Moya EA, Iturriaga R. PMID: 25429271; PMCID: PMC4228839.

View in: PubMed Mentions: 21
Chronic hypoxia induces the activation of the Wnt/β-catenin signaling pathway and stimulates hippocampal neurogenesis in wild-type and APPswe-PS1ΔE9 transgenic mice in vivo. Front Cell Neurosci. 2014; 8:17. Varela-Nallar L, Rojas-Abalos M, Abbott AC, Moya EA, Iturriaga R, Inestrosa NC. PMID: 24574965; PMCID: PMC3918655.

View in: PubMed Mentions: 42
Effect of insular cortex inactivation on autonomic and behavioral responses to acute hypoxia in conscious rats. Behav Brain Res. 2013 Sep 15; 253:60-7. Casanova JP, Contreras M, Moya EA, Torrealba F, Iturriaga R. PMID: 23860120.

View in: PubMed Mentions: 5 Fields:
Beh Behavioral Sciences Bra Brain
Translation:Animals
NO modulation of carotid body chemoreception in health and disease. Respir Physiol Neurobiol. 2012 Nov 15; 184(2):158-64. Moya EA, Alcayaga J, Iturriaga R. PMID: 22516266.

View in: PubMed Mentions: 16 Fields:
Pul Pulmonary Medicine
Translation:Humans Animals Cells
Rabbit ventilatory responses to peripheral chemoexcitators: effects of chronic hypoxia. Adv Exp Med Biol. 2012; 758:307-13. Alcayaga J, Del Rio R, Moya EA, Freire M, Iturriaga R. PMID: 23080177.

View in: PubMed Mentions: 1 Fields:
Bio Biology Med Medicine (General)
Translation:Animals Cells
Contribution of inflammation on carotid body chemosensory potentiation induced by intermittent hypoxia. Adv Exp Med Biol. 2012; 758:199-205. Del Rio R, Moya EA, Iturriaga R. PMID: 23080163.

View in: PubMed Mentions: 18 Fields:
Bio Biology Med Medicine (General)
Translation:Animals Cells
Carotid body inflammation and cardiorespiratory alterations in intermittent hypoxia. Eur Respir J. 2012 Jun; 39(6):1492-500. Del Rio R, Moya EA, Parga MJ, Madrid C, Iturriaga R. PMID: 22183481.

View in: PubMed Mentions: 60 Fields:
Pul Pulmonary Medicine
Translation:Animals Cells
Chronic intermittent hypoxia-induced vascular enlargement and VEGF upregulation in the rat carotid body is not prevented by antioxidant treatment. Am J Physiol Lung Cell Mol Physiol. 2011 Nov; 301(5):L702-11. Del Rio R, Muñoz C, Arias P, Court FA, Moya EA, Iturriaga R. PMID: 21821731.

View in: PubMed Mentions: 25 Fields:
Cel Cell Biology Mol Molecular Biology Phy Physiology Pul Pulmonary Medicine
Translation:Animals Cells
Differential expression of pro-inflammatory cytokines, endothelin-1 and nitric oxide synthases in the rat carotid body exposed to intermittent hypoxia. Brain Res. 2011 Jun 13; 1395:74-85. Del Rio R, Moya EA, Iturriaga R. PMID: 21555119.

View in: PubMed Mentions: 36 Fields:
Bra Brain
Translation:Animals Cells
Cardiorespiratory alterations induced by intermittent hypoxia in a rat model of sleep apnea. Adv Exp Med Biol. 2010; 669:271-4. Iturriaga R, Moya EA, Del Rio R. PMID: 20217364.

View in: PubMed Mentions: 14 Fields:
Bio Biology Med Medicine (General)
Translation:Animals
Carotid body and cardiorespiratory alterations in intermittent hypoxia: the oxidative link. Eur Respir J. 2010 Jul; 36(1):143-50. Del Rio R, Moya EA, Iturriaga R. PMID: 19996187.

View in: PubMed Mentions: 57 Fields:
Pul Pulmonary Medicine
Translation:Animals Cells
Carotid body potentiation induced by intermittent hypoxia: implications for cardiorespiratory changes induced by sleep apnoea. Clin Exp Pharmacol Physiol. 2009 Dec; 36(12):1197-204. Iturriaga R, Moya EA, Del Rio R. PMID: 19473190.

View in: PubMed Mentions: 31 Fields:
Pha Pharmacology Phy Physiology
Translation:Humans Animals Cells
Cardioventilatory acclimatization induced by chronic intermittent hypoxia. Adv Exp Med Biol. 2009; 648:329-35. Iturriaga R, Rey S, Del Rio R, Moya EA, Alcayaga J. PMID: 19536496.

View in: PubMed Mentions: 4 Fields:
Bio Biology Med Medicine (General)
Translation:Animals
Evidence for histamine as a new modulator of carotid body chemoreception. Adv Exp Med Biol. 2009; 648:177-84. Rio RD, Moya EA, Alcayaga J, Iturriaga R. PMID: 19536479.

View in: PubMed Mentions: 4 Fields:
Bio Biology Med Medicine (General)
Translation:Animals Cells
Modulatory effects of histamine on cat carotid body chemoreception. Respir Physiol Neurobiol. 2008 Dec 31; 164(3):401-10. Del Rio R, Moya EA, Koenig CS, Fujiwara K, Alcayaga J, Iturriaga R. PMID: 18824142.

View in: PubMed Mentions: 7 Fields:
Pul Pulmonary Medicine
Translation:Animals Cells