William Trogler

Title(s)	Emeritus Professor, Chemistry and Biochemistry
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
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Research

Research Activities and Funding

Center of Nanotechnology for Treatment, Understanding, *
NIH U54CA119335Sep 30, 2005 - Dec 31, 2011
Role: Co-Investigator

DETECTION AND MODELS OF TOXICANT EXPOSURE
NIH P42ES010337Jul 1, 2000 - Mar 31, 2022
Role: Co-Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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A Local and Abscopal Effect Observed with Liposomal Encapsulation of Intratumorally Injected Oncolytic Adenoviral Therapy. Cancers (Basel). 2023 Jun 12; 15(12). Dong T, Shah JR, Phung AT, Larson C, Sanchez AB, Aisagbonhi O, Blair SL, Oronsky B, Trogler WC, Reid T, Kummel AC. PMID: 37370769; PMCID: PMC10296131.

View in: PubMed Mentions: 2
Full Remission of CAR-Deficient Tumors by DOTAP-Folate Liposome Encapsulation of Adenovirus. ACS Biomater Sci Eng. 2022 Nov 17. Huang CH, Dong T, Phung AT, Shah JR, Larson C, Sanchez AB, Blair SL, Oronsky B, Trogler WC, Reid T, Kummel AC. PMID: 36395425.

View in: PubMed Mentions: 5 Fields:
Bio Biomedical Engineering Bio Biotechnology
Development of Adenovirus Containing Liposomes Produced by Extrusion vs. Homogenization: A Comparison for Scale-Up Purposes. Bioengineering (Basel). 2022 Oct 27; 9(11). Shah JR, Dong T, Phung AT, Reid T, Larson C, Sanchez AB, Oronsky B, Blair SL, Aisagbonhi O, Trogler WC, Kummel AC. PMID: 36354531; PMCID: PMC9687354.

View in: PubMed Mentions: 1
Immunostimulatory TLR7 agonist-nanoparticles together with checkpoint blockade for effective cancer immunotherapy. Adv Ther (Weinh). 2020 Jun; 3(6). Huang CH, Mendez N, Echeagaray OH, Weeks J, Wang J, Yao S, Blair SL, Gude N, Trogler WC, Carson DA, Hayashi T, Kummel AC. PMID: 33644299; PMCID: PMC7904104.

View in: PubMed Mentions: 5
Indocyanine green modified silica shells for colon tumor marking. Appl Surf Sci. 2020 Jan 01; 499. Badaracco AG, Ward E, Barback C, Yang J, Wang J, Huang CH, Kim M, Wang Q, Nam S, Delong J, Blair S, Trogler WC, Kummel A. PMID: 32863496; PMCID: PMC7455021.

View in: PubMed Mentions: 2
Conjugation of a Small-Molecule TLR7 Agonist to Silica Nanoshells Enhances Adjuvant Activity. ACS Appl Mater Interfaces. 2019 Jul 31; 11(30):26637-26647. Huang CH, Mendez N, Echeagaray OH, Weeks J, Wang J, Vallez CN, Gude N, Trogler WC, Carson DA, Hayashi T, Kummel AC. PMID: 31276378.

View in: PubMed Mentions: 5 Fields:
Bio Biomedical Engineering Bio Biotechnology
Translation:Humans Animals Cells
Thickness and Sphericity Control of Hollow Hard Silica Shells through Iron (III) Doping: Low Threshold Ultrasound Contrast Agents. Adv Funct Mater. 2019 Aug 15; 29(33). Huang CH, Wang J, Yang J, Oviedo JP, Nam S, Trogler WC, Blair SL, Kim MJ, Kummel AC. PMID: 34326713; PMCID: PMC8318338.

View in: PubMed Mentions:
MRI-guided transurethral insonation of silica-shell phase-shift emulsions in the prostate with an advanced navigation platform. Med Phys. 2019 Feb; 46(2):774-788. Anthony GJ, Bader KB, Wang J, Zamora M, Ostdiek A, Antic T, Krueger S, Weiss S, Trogler WC, Blair SL, Kummel AC, Sammet S. PMID: 30414276; PMCID: PMC6367027.

View in: PubMed Mentions: 2 Fields:
Bio Biophysics Phy Physics Rad Radiology Rad Radiotherapy
Translation:Animals
Identifying lost surgical needles with visible and near infrared fluorescent light emitting microscale coating. Surgery. 2018 04; 163(4):883-888. Ward EP, Yang J, Delong JC, Sung TW, Wang J, Barback C, Mendez N, Horgan S, Trogler W, Kummel AC, Blair SL. PMID: 29338879.

View in: PubMed Mentions: 3 Fields:
Gen General Surgery
Translation:Animals
Extended Lifetime In Vivo Pulse Stimulated Ultrasound Imaging. IEEE Trans Med Imaging. 2018 01; 37(1):222-229. Wang J, Barback CV, Ta CN, Weeks J, Gude N, Mattrey RF, Blair SL, Trogler WC, Lee H, Kummel AC. PMID: 28829305; PMCID: PMC5868352.

View in: PubMed Mentions: 5 Fields:
Dia Diagnostic Imaging
Translation:Animals
A Highly Sensitive Enzymatic Catalysis System for Trace Detection of Arsenic in Water. Chemistry. 2017 Aug 01; 23(43):10289-10292. Liu Y, Yu C, Cao Z, Shvarts D, Trogler WC. PMID: 28631380; PMCID: PMC5665019.

View in: PubMed Mentions: 2 Fields:
Che Chemistry
Translation:Humans Cells
Silica Shells/Adhesive Composite Film for Color Doppler Ultrasound Guided Needle Placement. ACS Biomater Sci Eng. 2017 Aug 14; 3(8):1780-1787. Yang J, Ward E, Sung TW, Wang J, Barback C, Mendez N, Blair S, Trogler WC, Kummel AC. PMID: 33429658.

View in: PubMed Mentions: 1 Fields:
Bio Biomedical Engineering Bio Biotechnology
Ultrasound Responsive Macrophase-Segregated Microcomposite Films for in Vivo Biosensing. ACS Appl Mater Interfaces. 2017 Jan 18; 9(2):1719-1727. Yang J, Wang J, Ta CN, Ward E, Barback CV, Sung TW, Mendez N, Blair SL, Kummel AC, Trogler WC. PMID: 28001041.

View in: PubMed Mentions: 1 Fields:
Bio Biomedical Engineering Bio Biotechnology
Assessment of in vivo systemic toxicity and biodistribution of iron-doped silica nanoshells. Nanomedicine. 2017 04; 13(3):933-942. Mendez N, Liberman A, Corbeil J, Barback C, Viveros R, Wang J, Wang-Rodriguez J, Blair SL, Mattrey R, Vera D, Trogler W, Kummel AC. PMID: 27840314.

View in: PubMed Mentions: 5 Fields:
Bio Biotechnology Nan Nanotechnology
Translation:Animals
Utilization of iron (III)-doped nanoshells for in vivo marking of nonpalpable tumors using a VX2 rabbit model. Am J Surg. 2016 Dec; 212(6):1140-1146. Ward EP, Wang J, Mendez N, Yang J, Barback C, Wang-Rodriguez J, Trogler W, Kummel AC, Blair S. PMID: 27776757; PMCID: PMC5138116.

View in: PubMed Mentions: 1 Fields:
Gen General Surgery
Translation:Animals
Comment on 'Fluorescence sensing of arsenate at nanomolar level in a greener way: naphthalene based probe for living cell imaging'. Chem Commun (Camb). 2015 Oct 11; 51(79):14775-7. Liu Y, Trogler WC. PMID: 26299989; PMCID: PMC4607275.

View in: PubMed Mentions: 1 Fields:
Che Chemistry
Translation:Animals
Quantification of endocytosis using a folate functionalized silica hollow nanoshell platform. J Biomed Opt. 2015 Aug; 20(8):88003. Sandoval S, Mendez N, Alfaro JG, Yang J, Aschemeyer S, Liberman A, Trogler WC, Kummel AC. PMID: 26315280; PMCID: PMC5996829.

View in: PubMed Mentions: Fields:
Bio Biomedical Engineering Oph Ophthalmology
Translation:Humans Cells
Mechanically Tunable Hollow Silica Ultrathin Nanoshells for Ultrasound Contrast Agents. Adv Funct Mater. 2015 Jul 08; 25(26):4049-4057. Liberman A, Wang J, Lu N, Viveros RD, Allen CA, Mattrey RF, Blair SL, Trogler WC, Kim MJ, Kummel AC. PMID: 26955300; PMCID: PMC4778971.

View in: PubMed Mentions: 19
Alkaline and ultrasonic dissolution of biological materials for trace silicon determination. J Vac Sci Technol B Nanotechnol Microelectron. 2015 May; 33(3):031803. Viveros RD, Liberman A, Trogler WC, Kummel AC. PMID: 25909037; PMCID: PMC4385096.

View in: PubMed Mentions: 3
Self-assembled Targeting of Cancer Cells by Iron(III)-doped, Silica Nanoparticles. J Mater Chem B. 2014 Dec 07; 2(45):8017-8025. Mitchell KK, Sandoval S, Cortes-Mateos MJ, Alfaro JG, Kummel AC, Trogler WC. PMID: 25364507; PMCID: PMC4214387.

View in: PubMed Mentions: 3 Fields:
Bio Biochemistry Bio Biotechnology Nan Nanotechnology
Synthesis and surface functionalization of silica nanoparticles for nanomedicine. Surf Sci Rep. 2014 Sep; 69(2-3):132-158. Liberman A, Mendez N, Trogler WC, Kummel AC. PMID: 25364083; PMCID: PMC4212223.

View in: PubMed Mentions: 95
Encapsulation of adenovirus serotype 5 in anionic lecithin liposomes using a bead-based immunoprecipitation technique enhances transfection efficiency. Biomaterials. 2014 Nov; 35(35):9554-61. Mendez N, Herrera V, Zhang L, Hedjran F, Feuer R, Blair SL, Trogler WC, Reid TR, Kummel AC. PMID: 25154663; PMCID: PMC4157089.

View in: PubMed Mentions: 24 Fields:
Bio Biomedical Engineering
Translation:Humans Animals Cells
Hollow iron-silica nanoshells for enhanced high intensity focused ultrasound. J Surg Res. 2014 Aug; 190(2):391-8. Liberman A, Wu Z, Barback CV, Viveros RD, Wang J, Ellies LG, Mattrey RF, Trogler WC, Kummel AC, Blair SL. PMID: 24972734; PMCID: PMC4141695.

View in: PubMed Mentions: 16 Fields:
Gen General Surgery
Translation:Humans Animals
Dual-porosity hollow nanoparticles for the immunoprotection and delivery of nonhuman enzymes. Nano Lett. 2014 Jun 11; 14(6):3023-32. Ortac I, Simberg D, Yeh YS, Yang J, Messmer B, Trogler WC, Tsien RY, Esener S. PMID: 24471767; PMCID: PMC4059531.

View in: PubMed Mentions: 7 Fields:
Nan Nanotechnology
Translation:Animals Cells
Luminescent tris(8-hydroxyquinolates) of bismuth(III). Inorg Chem. 2013 Oct 21; 52(20):12033-45. Han PJ, Rheingold AL, Trogler WC. PMID: 24093446.

View in: PubMed Mentions: Fields:
Che Chemistry
Atomic imaging of the irreversible sensing mechanism of NO2 adsorption on copper phthalocyanine. J Am Chem Soc. 2013 Oct 02; 135(39):14600-9. Park JH, Royer JE, Chagarov E, Kaufman-Osborn T, Edmonds M, Kent T, Lee S, Trogler WC, Kummel AC. PMID: 23968338.

View in: PubMed Mentions: 4 Fields:
Che Chemistry
Color Doppler ultrasound and gamma imaging of intratumorally injected 500 nm iron-silica nanoshells. ACS Nano. 2013 Jul 23; 7(7):6367-77. Liberman A, Wu Z, Barback CV, Viveros R, Blair SL, Ellies LG, Vera DR, Mattrey RF, Kummel AC, Trogler WC. PMID: 23802554; PMCID: PMC3777724.

View in: PubMed Mentions: 22 Fields:
Nan Nanotechnology
Translation:Animals Cells
Europium Doped TiO(2) Hollow Nanoshells: Two-Photon Imaging of Cell Binding. Chem Mater. 2012 Nov 13; 24(21):4222-4230. Sandoval S, Yang J, Alfaro JG, Liberman A, Makale M, Chiang CE, Schuller IK, Kummel AC, Trogler WC. PMID: 23185106; PMCID: PMC3505027.

View in: PubMed Mentions: 4
Iron(III)-doped, silica nanoshells: a biodegradable form of silica. J Am Chem Soc. 2012 Aug 29; 134(34):13997-4003. Pohaku Mitchell KK, Liberman A, Kummel AC, Trogler WC. PMID: 22871140; PMCID: PMC3433803.

View in: PubMed Mentions: 18 Fields:
Che Chemistry
Translation:Humans Animals
Hollow silica and silica-boron nano/microparticles for contrast-enhanced ultrasound to detect small tumors. Biomaterials. 2012 Jul; 33(20):5124-9. Liberman A, Martinez HP, Ta CN, Barback CV, Mattrey RF, Kono Y, Blair SL, Trogler WC, Kummel AC, Wu Z. PMID: 22498299; PMCID: PMC3588157.

View in: PubMed Mentions: 33 Fields:
Bio Biomedical Engineering
Translation:Humans
Air-stable spin-coated naphthalocyanine transistors for enhanced chemical vapor detection. Langmuir. 2012 Apr 10; 28(14):6192-200. Royer JE, Zhang C, Kummel AC, Trogler WC. PMID: 22376236.

View in: PubMed Mentions: Fields:
Che Chemistry
Integrated processing of contrast pulse sequencing ultrasound imaging for enhanced active contrast of hollow gas filled silica nanoshells and microshells. J Vac Sci Technol B Nanotechnol Microelectron. 2012 Mar; 30(2):2C104. Ta CN, Liberman A, Paul Martinez H, Barback CV, Mattrey RF, Blair SL, Trogler WC, Kummel AC, Wu Z. PMID: 23616935; PMCID: PMC3463889.

View in: PubMed Mentions: 8
Red-luminescent europium (III) doped silica nanoshells: synthesis, characterization, and their interaction with HeLa cells. J Biomed Opt. 2011 Jun; 16(6):066012. Yang J, Sandoval S, Alfaro JG, Aschemeyer S, Liberman A, Martin DT, Makale M, Kummel AC, Trogler WC. PMID: 21721813; PMCID: PMC3133801.

View in: PubMed Mentions: 11 Fields:
Bio Biomedical Engineering Oph Ophthalmology
Translation:Humans Cells
Hard shell gas-filled contrast enhancement particles for colour Doppler ultrasound imaging of tumors. Medchemcomm. 2010 Oct; 1(4):266-270. Martinez HP, Kono Y, Blair SL, Sandoval S, Wang-Rodriguez J, Mattrey RF, Kummel AC, Trogler WC. PMID: 21841967; PMCID: PMC3155153.

View in: PubMed Mentions: 30
Hollow silica nanospheres containing a silafluorene-fluorene conjugated polymer for aqueous TNT and RDX detection. Chem Commun (Camb). 2010 Sep 28; 46(36):6804-6. Yang J, Aschemeyer S, Martinez HP, Trogler WC. PMID: 20737079.

View in: PubMed Mentions: 1 Fields:
Che Chemistry
Lewis acid-base interactions enhance explosives sensing in silacycle polymers. Anal Bioanal Chem. 2009 Sep; 395(2):387-92. Sanchez JC, DiPasquale AG, Mrse AA, Trogler WC. PMID: 19506842; PMCID: PMC2727583.

View in: PubMed Mentions: 1 Fields:
Che Chemistry Techniques
A density functional theory study of the correlation between analyte basicity, ZnPc adsorption strength, and sensor response. J Chem Phys. 2009 May 28; 130(20):204307. Tran NL, Bohrer FI, Trogler WC, Kummel AC. PMID: 19485449.

View in: PubMed Mentions: 2 Fields:
Bio Biophysics Che Chemistry Phy Physics
NO chemisorption dynamics on thick FePc and ttbu-FePc films. J Chem Phys. 2009 May 07; 130(17):174305. Tran NL, Bishop SR, Grassman TJ, Poon GC, Bohrer FI, Trogler WC, Kummel AC. PMID: 19425774.

View in: PubMed Mentions: Fields:
Bio Biophysics Che Chemistry Phy Physics
Analyte chemisorption and sensing on n- and p-channel copper phthalocyanine thin-film transistors. J Chem Phys. 2009 Apr 28; 130(16):164703. Yang RD, Park J, Colesniuc CN, Schuller IK, Royer JE, Trogler WC, Kummel AC. PMID: 19405612.

View in: PubMed Mentions: 2 Fields:
Bio Biophysics Che Chemistry Phy Physics
Comparative gas sensing in cobalt, nickel, copper, zinc, and metal-free phthalocyanine chemiresistors. J Am Chem Soc. 2009 Jan 21; 131(2):478-85. Bohrer FI, Colesniuc CN, Park J, Ruidiaz ME, Schuller IK, Kummel AC, Trogler WC. PMID: 19093852.

View in: PubMed Mentions: 26 Fields:
Che Chemistry
Translation:Cells
Automated microscopy to evaluate surgical specimens via touch prep in breast cancer. Ann Surg Oncol. 2009 Mar; 16(3):709-20. Cortes-Mateos MJ, Martin D, Sandoval S, Ruidiaz ME, Messmer D, Wang-Rodriguez J, Trogler W, Kummel AC, Blair SL. PMID: 19137376; PMCID: PMC3154836.

View in: PubMed Mentions: 2 Fields:
Gen General Surgery Neo Neoplasms
Translation:Humans
Selective detection of vapor phase hydrogen peroxide with phthalocyanine chemiresistors. J Am Chem Soc. 2008 Mar 26; 130(12):3712-3. Bohrer FI, Colesniuc CN, Park J, Schuller IK, Kummel AC, Trogler WC. PMID: 18321103.

View in: PubMed Mentions: 8 Fields:
Che Chemistry
Translation:Cells
Selective detection of trace nitroaromatic, nitramine, and nitrate ester explosive residues using a three-step fluorimetric sensing process: a tandem turn-off, turn-on sensor. J Forensic Sci. 2007 Nov; 52(6):1308-13. Sanchez JC, Toal SJ, Wang Z, Dugan RE, Trogler WC. PMID: 17944906.

View in: PubMed Mentions: 2 Fields:
For Forensic Sciences Jur Jurisprudence
Enhanced touch preps improve the ease of interpretation of intraoperative breast cancer margins. Am Surg. 2007 Oct; 73(10):973-6. Blair SL, Wang-Rodriguez J, Cortes-Mateos MJ, Messmer D, Sandoval S, Messmer B, Trogler W, Kummel A. PMID: 17983060.

View in: PubMed Mentions: 4 Fields:
Gen General Surgery
Translation:Humans
Gas sensing mechanism in chemiresistive cobalt and metal-free phthalocyanine thin films. J Am Chem Soc. 2007 May 02; 129(17):5640-6. Bohrer FI, Sharoni A, Colesniuc C, Park J, Schuller IK, Kummel AC, Trogler WC. PMID: 17411043.

View in: PubMed Mentions: 12 Fields:
Che Chemistry
Visual detection of trace nitroaromatic explosive residue using photoluminescent metallole-containing polymers. J Forensic Sci. 2007 Jan; 52(1):79-83. Toal SJ, Sanchez JC, Dugan RE, Trogler WC. PMID: 17209914.

View in: PubMed Mentions: 4 Fields:
For Forensic Sciences Jur Jurisprudence
Electrode independent chemoresistive response for cobalt phthalocyanine in the space charge limited conductivity regime. J Phys Chem B. 2006 Jan 12; 110(1):361-6. Miller KA, Yang RD, Hale MJ, Park J, Fruhberger B, Colesniuc CN, Schuller IK, Kummel AC, Trogler WC. PMID: 16471543.

View in: PubMed Mentions: Fields:
Che Chemistry
Luminescent oligo(tetraphenyl)silole nanoparticles as chemical sensors for aqueous TNT. Chem Commun (Camb). 2005 Nov 21; (43):5465-7. Toal SJ, Magde D, Trogler WC. PMID: 16261248.

View in: PubMed Mentions: 7 Fields:
Che Chemistry
Luminescent silole nanoparticles as chemoselective sensors for Cr(VI). J Am Chem Soc. 2005 Aug 24; 127(33):11661-5. Toal SJ, Jones KA, Magde D, Trogler WC. PMID: 16104742.

View in: PubMed Mentions: 12 Fields:
Che Chemistry
Detection of nitroaromatic explosives based on photoluminescent polymers containing metalloles. J Am Chem Soc. 2003 Apr 02; 125(13):3821-30. Sohn H, Sailor MJ, Magde D, Trogler WC. PMID: 12656615.

View in: PubMed Mentions: 21 Fields:
Che Chemistry
Detection of TNT and Picric Acid on Surfaces and in Seawater by Using Photoluminescent Polysiloles This work was supported through DARPA's Tactical Sensors Program through a Space and Naval Warfare Systems Center Contract (N66001-98-C-8514) and the National Science Foundation, Division of Material Research (Grant No. DMR 9900034). The technical point of contact for this DARPA program is Dr. Edward Carapezza. Angew Chem Int Ed Engl. 2001 Jun 01; 40(11):2104-2105. Sohn H, Calhoun RM, Sailor MJ, Trogler WC. PMID: 11433457.

View in: PubMed Mentions: 2 Fields:
Che Chemistry
Detection of TNT and Picric Acid on Surfaces and in Seawater by Using Photoluminescent Polysiloles. Angew Chem Int Ed Engl. 2001 Jun 01; 40(11):2104-2105. Sohn H, Calhoun RM, Sailor MJ, Trogler WC. PMID: 29712198.

View in: PubMed Mentions: 6 Fields:
Che Chemistry
Photopolymerization of liquid carbon disulfide produces nanoscale polythiene films. J Am Chem Soc. 2001 Feb 14; 123(6):1199-207. Zmolek PB, Sohn H, Gantzel PK, Trogler WC. PMID: 11456674.

View in: PubMed Mentions: Fields:
Che Chemistry
Nylon production: an unknown source of atmospheric nitrous oxide. Science. 1991 Feb 22; 251(4996):932-4. Thiemens MH, Trogler WC. PMID: 17847387.

View in: PubMed Mentions: 9 Fields:
Sci Science
Catalytic hydration of terminal alkenes to primary alcohols. Science. 1986 Sep 05; 233(4768):1069-71. Jensen CM, Trogler WC. PMID: 17746578.

View in: PubMed Mentions: 2 Fields:
Sci Science
Unexpected dissociative kinetics for carbon monoxide exchange in the 17-electron complexes carbonylbis(.eta.5-pentadienyl)vanadium(II), carbonyl(.eta.5-cyclopentadienyl)(.eta.5-pentadienyl)vanadium(II), and carbonyl(.eta.5-cyclopentadienyl)(.eta.5-2,4-dimethylpentadienyl)vanadium(II). J Am Chem Soc. 1986 Sep 01; 108(19):6046-8. Kowaleski RM, Basolo F, Trogler WC, Ernst RD. PMID: 22175375.

View in: PubMed Mentions: Fields:
Che Chemistry
Synthesis and structure of dicarbonyl(.eta.3-indenyl)(.eta.5-indenyl)vanadium(II). An unusual slipped ring in a metal radical. J Am Chem Soc. 1986 Apr 01; 108(9):2460-1. Kowaleski RM, Rheingold AL, Trogler WC, Basolo F. PMID: 22175609.

View in: PubMed Mentions: Fields:
Che Chemistry