Rui Carlos Pereira De Sa

Title(s)	Assistant Adjunct Professor, Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Biography

Education and Training

Université Libre de Bruxelles, Brussels, Belgium	Ph.D.	2008	Medicine
Instituto Superior Técnico, Lisbon, Portugal	Engineer in Physics	1998	Physics

Awards and Honors

International Society for Aerosols in Medicine

2017

Willi Stahlhofen Experimental Award for Outstanding Research in the Field of Aerosols

ORNG Applications

Featured Publications

Faculty Mentoring

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Heavy upright exercise increases ventilation-perfusion mismatch in the basal lung: indirect evidence for interstitial pulmonary edema. J Appl Physiol (1985). 2019 08 01; 127(2):473-481. Tedjasaputra V, Sá RC, Anderson KM, Prisk GK, Hopkins SR. PMID: 31246558; PMCID: PMC6732434.

View in: PubMed Mentions: 3 Fields:
Phy Physiology
Translation:Humans
Regional pulmonary perfusion patterns in humans are not significantly altered by inspiratory hypercapnia. J Appl Physiol (1985). 2019 08 01; 127(2):365-375. Asadi AK, Sá RC, Arai TJ, Theilmann RJ, Hopkins SR, Buxton RB, Prisk GK. PMID: 31169470; PMCID: PMC6732437.

View in: PubMed Mentions: 5 Fields:
Phy Physiology
Translation:Humans
Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent. J Vis Exp. 2019 06 05; (148). Geier ET, Theilmann RJ, Darquenne C, Prisk GK, Sá RC. PMID: 31233033; PMCID: PMC6743506.

View in: PubMed Mentions: 2 Fields:
Bio Biology Med Medicine (General)
Translation:Humans
Regional airflow obstruction after bronchoconstriction and subsequent bronchodilation in subjects without pulmonary disease. J Appl Physiol (1985). 2019 07 01; 127(1):31-39. Geier ET, Theilmann RJ, Prisk GK, Sá RC. PMID: 31120808; PMCID: PMC7276920.

View in: PubMed Mentions: 2 Fields:
Phy Physiology
Translation:Humans
The spatial pattern of methacholine bronchoconstriction recurs when supine independently of posture during provocation but does not recur between postures. J Appl Physiol (1985). 2018 Dec 01; 125(6):1720-1730. Geier ET, Kubo K, Theilmann RJ, Prisk GK, Sá RC. PMID: 30188793; PMCID: PMC10392630.

View in: PubMed Mentions: 4 Fields:
Phy Physiology
Comparison of quantitative multiple-breath specific ventilation imaging using colocalized 2D oxygen-enhanced MRI and hyperpolarized 3He MRI. J Appl Physiol (1985). 2018 11 01; 125(5):1526-1535. Arai TJ, Horn FC, Sá RC, Rao MR, Collier GJ, Theilmann RJ, Prisk GK, Wild JM. PMID: 30161004; PMCID: PMC6295484.

View in: PubMed Mentions: 6 Fields:
Phy Physiology
Translation:Humans
In silico modeling of oxygen-enhanced MRI of specific ventilation. Physiol Rep. 2018 04; 6(7):e13659. Kang W, Tawhai MH, Clark AR, Sá RC, Geier ET, Prisk GK, Burrowes KS. PMID: 29659198; PMCID: PMC5900997.

View in: PubMed Mentions: 5 Fields:
Phy Physiology
Translation:Humans
Pulmonary Delivery of Therapeutic and Diagnostic Gases. J Aerosol Med Pulm Drug Deliv. 2018 04; 31(2):78-87. Zapol WM, Charles HC, Martin AR, Sá RC, Yu B, Ichinose F, MacIntyre N, Mammarappallil J, Moon R, Chen JZ, Geier ET, Darquenne C, Prisk GK, Katz I. PMID: 29451844; PMCID: PMC6421997.

View in: PubMed Mentions: 2 Fields:
Dru Drug Therapy Pul Pulmonary Medicine
Translation:Humans
Spatial persistence of reduced specific ventilation following methacholine challenge in the healthy human lung. J Appl Physiol (1985). 2018 05 01; 124(5):1222-1232. Geier ET, Neuhart I, Theilmann RJ, Prisk GK, Sá RC. PMID: 29420156; PMCID: PMC6008074.

View in: PubMed Mentions: 8 Fields:
Phy Physiology
Translation:Humans
Evidence from high-altitude acclimatization for an integrated cerebrovascular and ventilatory hypercapnic response but different responses to hypoxia. J Appl Physiol (1985). 2017 12 01; 123(6):1477-1486. Smith ZM, Krizay E, Sá RC, Li ET, Scadeng M, Powell FL, Dubowitz DJ. PMID: 28705997; PMCID: PMC6734088.

View in: PubMed Mentions: 4 Fields:
Phy Physiology
Translation:Humans
Regional Ventilation Is the Main Determinant of Alveolar Deposition of Coarse Particles in the Supine Healthy Human Lung During Tidal Breathing. J Aerosol Med Pulm Drug Deliv. 2017 Oct; 30(5):322-331. Sá RC, Zeman KL, Bennett WD, Prisk GK, Darquenne C. PMID: 28277885; PMCID: PMC5650708.

View in: PubMed Mentions: 4 Fields:
Dru Drug Therapy Pul Pulmonary Medicine
Translation:Humans
Measurement of the distribution of ventilation-perfusion ratios in the human lung with proton MRI: comparison with the multiple inert-gas elimination technique. J Appl Physiol (1985). 2017 Jul 01; 123(1):136-146. Sá RC, Henderson AC, Simonson T, Arai TJ, Wagner H, Theilmann RJ, Wagner PD, Prisk GK, Hopkins SR. PMID: 28280105; PMCID: PMC5538816.

View in: PubMed Mentions: 13 Fields:
Phy Physiology
Translation:Humans
Susceptibility to high-altitude pulmonary edema is associated with a more uniform distribution of regional specific ventilation. J Appl Physiol (1985). 2017 Apr 01; 122(4):844-852. Patz MD, Sá RC, Darquenne C, Elliott AR, Asadi AK, Theilmann RJ, Dubowitz DJ, Swenson ER, Prisk GK, Hopkins SR. PMID: 28057815; PMCID: PMC5407202.

View in: PubMed Mentions: 3 Fields:
Phy Physiology
Translation:Humans
The effect of lung deformation on the spatial distribution of pulmonary blood flow. J Physiol. 2016 11 01; 594(21):6333-6347. Arai TJ, Theilmann RJ, Sá RC, Villongco MT, Hopkins SR. PMID: 27273807; PMCID: PMC5088230.

View in: PubMed Mentions: 3 Fields:
Phy Physiology
Translation:Humans
Rapid Prototyping of Inspired Gas Delivery System for Pulmonary MRI Research. 3D Print Addit Manuf. 2015 Dec 01; 2(4):196-203. Cook FR, Geier ET, Asadi AK, Sá RC, Prisk GK. PMID: 27917393; PMCID: PMC4981153.

View in: PubMed Mentions: 8
Effect of Posture on Regional Deposition of Coarse Particles in the Healthy Human Lung. J Aerosol Med Pulm Drug Deliv. 2015 Dec; 28(6):423-31. Sá RC, Zeman KL, Bennett WD, Prisk GK, Darquenne C. PMID: 25826480.

View in: PubMed Mentions: 10 Fields:
Dru Drug Therapy Pul Pulmonary Medicine
Translation:Humans
Inhaled nitric oxide alters the distribution of blood flow in the healthy human lung, suggesting active hypoxic pulmonary vasoconstriction in normoxia. J Appl Physiol (1985). 2015 Feb 01; 118(3):331-43. Asadi AK, Sá RC, Kim NH, Theilmann RJ, Hopkins SR, Buxton RB, Prisk GK. PMID: 25429099; PMCID: PMC4312852.

View in: PubMed Mentions: 16 Fields:
Phy Physiology
Translation:Humans
Advances in functional and structural imaging of the human lung using proton MRI. NMR Biomed. 2014 Dec; 27(12):1542-56. Miller GW, Mugler JP, Sá RC, Altes TA, Prisk GK, Hopkins SR. PMID: 24990096; PMCID: PMC4515033.

View in: PubMed Mentions: 18 Fields:
Dia Diagnostic Imaging Nuc Nuclear Medicine
Translation:Humans
Validating the distribution of specific ventilation in healthy humans measured using proton MR imaging. J Appl Physiol (1985). 2014 Apr 15; 116(8):1048-56. Sá RC, Asadi AK, Theilmann RJ, Hopkins SR, Prisk GK, Darquenne C. PMID: 24505099; PMCID: PMC4035784.

View in: PubMed Mentions: 26 Fields:
Phy Physiology
Translation:Humans
It's about numbers, not pictures. J Appl Physiol (1985). 2014 Jan 15; 116(2):127-8. Prisk GK, Sá RC. PMID: 24356517.

View in: PubMed Mentions: Fields:
Phy Physiology
Translation:Humans
The effect of supine exercise on the distribution of regional pulmonary blood flow measured using proton MRI. J Appl Physiol (1985). 2014 Feb 15; 116(4):451-61. Hall ET, Sá RC, Holverda S, Arai TJ, Dubowitz DJ, Theilmann RJ, Prisk GK, Hopkins SR. PMID: 24356515; PMCID: PMC3921353.

View in: PubMed Mentions: 5 Fields:
Phy Physiology
Translation:Humans
Cardiogenic mixing increases aerosol deposition in the human lung in the absence of gravity. Acta Astronaut. 2013 Nov; 92(1):15-20. Prisk GK, Sá RC, Darquenne C. PMID: 23976801; PMCID: PMC3747654.

View in: PubMed Mentions: 3 Fields:
Aer Aerospace Medicine
Removal of sedimentation decreases relative deposition of coarse particles in the lung periphery. J Appl Physiol (1985). 2013 Aug 15; 115(4):546-55. Darquenne C, Zeman KL, Sá RC, Cooper TK, Fine JM, Bennett WD, Prisk GK. PMID: 23743403.

View in: PubMed Mentions: 8 Fields:
Phy Physiology
Translation:Humans
The heterogeneity of regional specific ventilation is unchanged following heavy exercise in athletes. J Appl Physiol (1985). 2013 Jul 01; 115(1):126-35. Tedjasaputra V, Sá RC, Arai TJ, Holverda S, Theilmann RJ, Chen WT, Wagner PD, Davis CK, Kim Prisk G, Hopkins SR. PMID: 23640585; PMCID: PMC3727009.

View in: PubMed Mentions: 10 Fields:
Phy Physiology
Translation:Humans
The gravitational distribution of ventilation-perfusion ratio is more uniform in prone than supine posture in the normal human lung. J Appl Physiol (1985). 2013 Aug 01; 115(3):313-24. Henderson AC, Sá RC, Theilmann RJ, Buxton RB, Prisk GK, Hopkins SR. PMID: 23620488; PMCID: PMC3743008.

View in: PubMed Mentions: 55 Fields:
Phy Physiology
Translation:Humans
Spatial-temporal dynamics of pulmonary blood flow in the healthy human lung in response to altered FI(O2). J Appl Physiol (1985). 2013 Jan 01; 114(1):107-18. Asadi AK, Cronin MV, Sá RC, Theilmann RJ, Holverda S, Hopkins SR, Buxton RB, Prisk GK. PMID: 23104691; PMCID: PMC3544514.

View in: PubMed Mentions: 11 Fields:
Phy Physiology
Translation:Humans
Rapid intravenous infusion of 20 mL/kg saline alters the distribution of perfusion in healthy supine humans. Respir Physiol Neurobiol. 2012 Mar 15; 180(2-3):331-41. Henderson AC, Sá RC, Barash IA, Holverda S, Buxton RB, Hopkins SR, Prisk GK. PMID: 22227320; PMCID: PMC3273583.

View in: PubMed Mentions: 6 Fields:
Pul Pulmonary Medicine
Translation:Humans
Measuring lung water: ex vivo validation of multi-image gradient echo MRI. J Magn Reson Imaging. 2011 Jul; 34(1):220-4. Holverda S, Theilmann RJ, Sá RC, Arai TJ, Hall ET, Dubowitz DJ, Prisk GK, Hopkins SR. PMID: 21698711; PMCID: PMC3122154.

View in: PubMed Mentions: 21 Fields:
Dia Diagnostic Imaging
Translation:Animals
Magnetic resonance imaging quantification of pulmonary perfusion using calibrated arterial spin labeling. J Vis Exp. 2011 May 30; (51). Arai TJ, Prisk GK, Holverda S, Sá RC, Theilmann RJ, Henderson AC, Cronin MV, Buxton RB, Hopkins SR. PMID: 21673635; PMCID: PMC3197117.

View in: PubMed Mentions: 11 Fields:
Bio Biology Med Medicine (General)
Translation:Humans
Vertical distribution of specific ventilation in normal supine humans measured by oxygen-enhanced proton MRI. J Appl Physiol (1985). 2010 Dec; 109(6):1950-9. Sá RC, Cronin MV, Henderson AC, Holverda S, Theilmann RJ, Arai TJ, Dubowitz DJ, Hopkins SR, Buxton RB, Prisk GK. PMID: 20930129; PMCID: PMC3006418.

View in: PubMed Mentions: 49 Fields:
Phy Physiology
Translation:Humans
Microgravity alters respiratory abdominal and rib cage motion during sleep. J Appl Physiol (1985). 2009 Nov; 107(5):1406-12. Sá RC, Prisk GK, Paiva M. PMID: 19779153; PMCID: PMC2777791.

View in: PubMed Mentions: 3 Fields:
Phy Physiology
Translation:Humans
A method for the analysis of respiratory sinus arrhythmia using continuous wavelet transforms. IEEE Trans Biomed Eng. 2008 May; 55(5):1640-2. Cnockaert L, Migeotte PF, Daubigny L, Prisk GK, Grenez F, Sá RC. PMID: 18440911.

View in: PubMed Mentions: 1 Fields:
Bio Biomedical Engineering
Translation:Humans
Automated breath detection on long-duration signals using feedforward backpropagation artificial neural networks. IEEE Trans Biomed Eng. 2002 Oct; 49(10):1130-41. Sá RC, Verbandt Y. PMID: 12374337.

View in: PubMed Mentions: 5 Fields:
Bio Biomedical Engineering
Translation:Humans
Dynamics of blood pressure, pulse wave transit time and systolic time intervals during acute gravity changes induced by parabolic flight. J Gravit Physiol. 2002 Jul; 9(1):P77-8. Migeotte PF, Dominique T, Sa RC. PMID: 14977001.

View in: PubMed Mentions: 2 Fields:
Phy Physiology
Noninvasive beat-to-beat stroke volume computation during acute hydrostatic pressure changes in parabolic flight. J Gravit Physiol. 2002 Jul; 9(1):P97-8. Dominique T, Migeotte PF, Sa RC. PMID: 15002500.

View in: PubMed Mentions: 2 Fields:
Phy Physiology