Larissa Traxler

Title(s)Assistant Project Scientist, Neurosciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. RUNX1 and YY1 modulate neuronal fate and energy metabolism in Alzheimer's disease. bioRxiv. 2026 Apr 14. Lucciola R, Herdy JR, Vajaphattana Y, Karbacher L, Sabedot TS, Cuoco MS, Traxler L, Kang A, Reynolds M, Jones JR, Schafer ST, Mertens J, Gage FH. PMID: 42039533; PMCID: PMC13104874.
      View in: PubMed   Mentions:
    2. Stable expression of voltage-gated calcium channel mRNA in α2δ (CACNA2D) knockout mouse brains. Neuroscience. 2025 08 06; 580:169-180. Geisler SM, Traxler L, Obermair GJ. PMID: 40543890.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    3. An accelerated human in-vitro aging model mimicsin-vivo aging and facilitates dynamic testing of anti-aging compounds. Res Sq. 2025 Mar 28. Mertens J, Traxler L, Karbacher L, Borgogno O, Ozbun T, Champion K, Smaling A, Boeckle B, Mack H, Defrancesco M. PMID: 40195985; PMCID: PMC11975038.
      View in: PubMed   Mentions:
    4. All roads lead to cholesterol: Modulating lipid biosynthesis in multiple sclerosis patient-derived models. Cell Stem Cell. 2024 Nov 07; 31(11):1551-1552. Eichhorner S, Traxler L, Borgogno O, Mertens J. PMID: 39515295.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Ignorance is bliss: Inhibition of proteomic stress sensing improves direct neuronal conversion. Neuron. 2024 04 03; 112(7):1035-1037. Traxler L, Borgogno O, Mertens J. PMID: 38574725.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    6. Neural cell state shifts and fate loss in ageing and age-related diseases. Nat Rev Neurol. 2023 07; 19(7):434-443. Traxler L, Lucciola R, Herdy JR, Jones JR, Mertens J, Gage FH. PMID: 37268723; PMCID: PMC10478103.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    7. Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's disease. Cell Stem Cell. 2022 12 01; 29(12):1637-1652.e6. Herdy JR, Traxler L, Agarwal RK, Karbacher L, Schlachetzki JCM, Boehnke L, Zangwill D, Galasko D, Glass CK, Mertens J, Gage FH. PMID: 36459967; PMCID: PMC10093780.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansCells
    8. Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's disease. Cell Metab. 2022 09 06; 34(9):1248-1263.e6. Traxler L, Herdy JR, Stefanoni D, Eichhorner S, Pelucchi S, Szücs A, Santagostino A, Kim Y, Agarwal RK, Schlachetzki JCM, Glass CK, Lagerwall J, Galasko D, Gage FH, D'Alessandro A, Mertens J. PMID: 35987203; PMCID: PMC9458870.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    9. Metabolism navigates neural cell fate in development, aging and neurodegeneration. Dis Model Mech. 2021 08 01; 14(8). Traxler L, Lagerwall J, Eichhorner S, Stefanoni D, D'Alessandro A, Mertens J. PMID: 34345916; PMCID: PMC8353098.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    10. Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients. Cell Stem Cell. 2021 09 02; 28(9):1533-1548.e6. Mertens J, Herdy JR, Traxler L, Schafer ST, Schlachetzki JCM, Böhnke L, Reid DA, Lee H, Zangwill D, Fernandes DP, Agarwal RK, Lucciola R, Zhou-Yang L, Karbacher L, Edenhofer F, Stern S, Horvath S, Paquola ACM, Glass CK, Yuan SH, Ku M, Szücs A, Goldstein LSB, Galasko D, Gage FH. PMID: 33910058; PMCID: PMC8423435.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansCells
    11. Direct Conversion of Human Fibroblasts to Induced Neurons. Methods Mol Biol. 2021; 2352:73-96. Zhou-Yang L, Eichhorner S, Karbacher L, Böhnke L, Traxler L, Mertens J. PMID: 34324181.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    12. Next-generation disease modeling with direct conversion: a new path to old neurons. FEBS Lett. 2019 12; 593(23):3316-3337. Traxler L, Edenhofer F, Mertens J. PMID: 31715002; PMCID: PMC6907729.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    13. Human neurons to model aging: A dish best served old. Drug Discov Today Dis Models. 2018; 27:43-49. Böhnke L, Traxler L, Herdy JR, Mertens J. PMID: 31745399; PMCID: PMC6863511.
      View in: PubMed   Mentions: 12  
    14. Presynaptic α2δ-2 Calcium Channel Subunits Regulate Postsynaptic GABAA Receptor Abundance and Axonal Wiring. J Neurosci. 2019 04 03; 39(14):2581-2605. Geisler S, Schöpf CL, Stanika R, Kalb M, Campiglio M, Repetto D, Traxler L, Missler M, Obermair GJ. PMID: 30683685; PMCID: PMC6445987.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    15. Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile. Cell Rep. 2018 05 29; 23(9):2550-2558. Kim Y, Zheng X, Ansari Z, Bunnell MC, Herdy JR, Traxler L, Lee H, Paquola ACM, Blithikioti C, Ku M, Schlachetzki JCM, Winkler J, Edenhofer F, Glass CK, Paucar AA, Jaeger BN, Pham S, Boyer L, Campbell BC, Hunter T, Mertens J, Gage FH. PMID: 29847787; PMCID: PMC6478017.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
    16. Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis. Cancer Cell. 2018 03 12; 33(3):417-434.e7. Mondal T, Juvvuna PK, Kirkeby A, Mitra S, Kosalai ST, Traxler L, Hertwig F, Wernig-Zorc S, Miranda C, Deland L, Volland R, Bartenhagen C, Bartsch D, Bandaru S, Engesser A, Subhash S, Martinsson T, Carén H, Akyürek LM, Kurian L, Kanduri M, Huarte M, Kogner P, Fischer M, Kanduri C. PMID: 29533783.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
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