Carlos Carrera

Title(s)Clinical Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    L ALANOSINE THERAPY FOR MTAP DEFICIENT LUNG CANCER
    NIH R21CA068260Apr 19, 1996 - Mar 31, 1999
    Role: Principal Investigator
    MECHANISMS OF PROGRAMMED CELL DEATH IN CHEMOTHERAPY
    NIH R29CA054892Jul 1, 1991 - Jun 30, 1996
    Role: Principal Investigator
    TOXICITY OF DNA DAMAGE IN NON-DIVIDING LYMPHOID CELLS
    NIH K08CA001100Jun 1, 1987 - Jun 30, 1990
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Injury, Illness, and Mental Health Risks in United States Domestic Mariners. J Occup Environ Med. 2020 10; 62(10):839-841. Lefkowitz RY, Null DB, Slade MD, Redlich CA. PMID: 32769797.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    2. Imaging examination, diagnosis, and control and prevention of nosocomial infection for coronavirus disease 2019: Expert consensus of Hunan radiologist. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2020 Mar 28; 45(3):221-228. Liu J, Wang W. PMID: 32386011.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    3. Effect of Antidepressant Switching vs Augmentation on Remission Among Patients With Major Depressive Disorder Unresponsive to Antidepressant Treatment: The VAST-D Randomized Clinical Trial. JAMA. 2017 Jul 11; 318(2):132-145. Mohamed S, Johnson GR, Chen P, Hicks PB, Davis LL, Yoon J, Gleason TC, Vertrees JE, Weingart K, Tal I, Scrymgeour A, Lawrence DD, Planeta B, Thase ME, Huang GD, Zisook S, and the VAST-D Investigators, Rao SD, Pilkinton PD, Wilcox JA, Iranmanesh A, Sapra M, Jurjus G, Michalets JP, Aslam M, Beresford T, Anderson KD, Fernando R, Ramaswamy S, Kasckow J, Westermeyer J, Yoon G, D'Souza DC, Larson G, Anderson WG, Klatt M, Fareed A, Thompson SI, Carrera CJ, Williams SS, Juergens TM, Albers LJ, Nasdahl CS, Villarreal G, Winston JL, Nogues CA, Connolly KR, Tapp A, Jones KA, Khatkhate G, Marri S, Suppes T, LaMotte J, Hurley R, Mayeda AR, Niculescu AB, Fischer BA, Loreck DJ, Rosenlicht N, Lieske S, Finkel MS, Little JT. PMID: 28697253; PMCID: PMC5817471.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    4. EFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine. Blood. 2006 Feb 01; 107(3):898-903. Batova A, Cottam H, Yu J, Diccianni MB, Carrera CJ, Yu AL. PMID: 16234352; PMCID: PMC1895892.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    5. A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer. Oncogene. 2000 Nov 23; 19(50):5747-54. Schmid M, Sen M, Rosenbach MD, Carrera CJ, Friedman H, Carson DA. PMID: 11126361.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    6. Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria. Blood. 2000 Nov 15; 96(10):3537-43. Genini D, Adachi S, Chao Q, Rose DW, Carrera CJ, Cottam HB, Carson DA, Leoni LM. PMID: 11071652.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    7. Rational design, synthesis and structure-activity relationships of antitumor (E)-2-benzylidene-1-tetralones and (E)-2-benzylidene-1-indanones. Bioorg Med Chem Lett. 2000 Mar 06; 10(5):487-90. Shih H, Deng L, Carrera CJ, Adachi S, Cottam HB, Carson DA. PMID: 10743954.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    8. Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells. J Natl Cancer Inst. 2000 Feb 02; 92(3):217-24. Leoni LM, Hamel E, Genini D, Shih H, Carrera CJ, Cottam HB, Carson DA. PMID: 10655438.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    9. Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway. J Biol Chem. 2000 Jan 07; 275(1):29-34. Genini D, Budihardjo I, Plunkett W, Wang X, Carrera CJ, Cottam HB, Carson DA, Leoni LM. PMID: 10617581.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    10. Use of alanosine as a methylthioadenosine phosphorylase-selective therapy for T-cell acute lymphoblastic leukemia in vitro. Cancer Res. 1999 Apr 01; 59(7):1492-7. Batova A, Diccianni MB, Omura-Minamisawa M, Yu J, Carrera CJ, Bridgeman LJ, Kung FH, Pullen J, Amylon MD, Yu AL. PMID: 10197619.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    11. Homozygous deletions of methylthioadenosine phosphorylase (MTAP) are more frequent than p16INK4A (CDKN2) homozygous deletions in primary non-small cell lung cancers (NSCLC). Oncogene. 1998 Nov 19; 17(20):2669-75. Schmid M, Malicki D, Nobori T, Rosenbach MD, Campbell K, Carson DA, Carrera CJ. PMID: 9840931.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    12. Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9567-71. Leoni LM, Chao Q, Cottam HB, Genini D, Rosenbach M, Carrera CJ, Budihardjo I, Wang X, Carson DA. PMID: 9689121; PMCID: PMC21379.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    13. The methylthioadenosine phosphorylase gene is frequently co-deleted with the p16INK4a gene in acute type adult T-cell leukemia. Int J Cancer. 1998 Jan 05; 75(1):51-6. Hori Y, Hori H, Yamada Y, Carrera CJ, Tomonaga M, Kamihira S, Carson DA, Nobori T. PMID: 9426690.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    14. Methylthioadenosine phosphorylase cDNA transfection alters sensitivity to depletion of purine and methionine in A549 lung cancer cells. Cancer Res. 1996 Dec 15; 56(24):5653-8. Hori H, Tran P, Carrera CJ, Hori Y, Rosenbach MD, Carson DA, Nobori T. PMID: 8971171.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    15. Oral 2-chlorodeoxyadenosine in psoriatic arthritis. A preliminary report. Arthritis Rheum. 1995 Nov; 38(11):1604-9. Eibschutz B, Baird SM, Weisman MH, Amox DG, Spellman M, Piacquadio D, Carrera CJ, Carson DA. PMID: 7488281.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Purine metabolism of lymphocytes. Targets for chemotherapy drug development. Hematol Oncol Clin North Am. 1994 Apr; 8(2):357-81. Carrera CJ, Saven A, Piro LD. PMID: 8040145.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    17. Relationship of deoxycytidine kinase and cytoplasmic 5'-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine. Blood. 1993 Feb 01; 81(3):597-601. Kawasaki H, Carrera CJ, Piro LD, Saven A, Kipps TJ, Carson DA. PMID: 8094016.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    18. Quantitative immunoassay of human deoxycytidine kinase in malignant cells. Anal Biochem. 1992 Nov 15; 207(1):193-6. Kawasaki H, Carrera CJ, Carson DA. PMID: 1489095.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    19. Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):2970-4. Carson DA, Wasson DB, Esparza LM, Carrera CJ, Kipps TJ, Cottam HB. PMID: 1348362; PMCID: PMC48785.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    20. Dependence of cell survival on DNA repair in human mononuclear phagocytes. J Immunol. 1991 Dec 15; 147(12):4302-6. Terai C, Wasson DB, Carrera CJ, Carson DA. PMID: 1753100.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    21. Deoxyadenosine-resistant human T lymphoblasts with elevated 5'-nucleotidase activity. Biochim Biophys Acta. 1991 Jan 10; 1091(1):22-8. Carson DA, Carrera CJ, Wasson DB, Iizasa T. PMID: 1995064.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    22. 2-Chlorodeoxyadenosine chemotherapy triggers programmed cell death in normal and malignant lymphocytes. Adv Exp Med Biol. 1991; 309A:15-8. Carrera CJ, Piro LD, Saven A, Beutler E, Terai C, Carson DA. PMID: 1686349.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
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