Alexander Kauffman

Photo of Alexander Kauffman
Title(s)Professor, Ob/Gyn & Reproductive sciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse education and training
    U.C. BerkeleyPhDIntegrative Biology
    University of VirginiaPostdocBehavioral Neuroscience
    University of WashingtonPostdocMolecular Neuroendocrinology

    Collapse Research 
    Collapse research activities and funding
    Androgen effects on the reproductive neuroendocrine axis
    NIH R01HD111650Dec 12, 2023 - Nov 30, 2028
    Role: Principal Investigator
    Neuroendocrine regulation of puberty and reproductive development
    NIH R01HD090161Sep 1, 2017 - May 31, 2022
    Role: Principal Investigator
    Project 2
    NIH P50 HD012303Aug 1, 2016 - Mar 31, 2021
    Role: Co-Investigator
    National Science Foundation NSF IOS-1457226Aug 1, 2015 - Jul 31, 2019
    Role: Principal Investigator
    NIH R01 HD082567Apr 1, 2015 - Jan 31, 2020
    Role: Co-Investigator
    Neuroendocrine regulation of the reproductive axis during puberty and development
    NIH R01HD065856Aug 10, 2010 - Dec 31, 2015
    Role: Principal Investigator
    National Science Foundation NSF IOS-1025893Aug 1, 2010 - Jul 31, 2015
    Role: Principal Investigator
    Role of Kiss1 neurons in the seasonal and circadian control of reproduction
    NIH R00HD056157Sep 1, 2007 - Mar 31, 2012
    Role: Principal Investigator
    Role of Kiss1 neurons in the seasonal and circadian control of reproduction
    NIH K99HD056157Sep 1, 2007 - Aug 31, 2009
    Role: Principal Investigator
    Neuroendocrine control of feeding and reproduction
    NIH F32MH070084May 1, 2004 - Apr 30, 2006
    Role: Principal Investigator

    Collapse Featured Content 

    Collapse Bibliographic 
    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Association of daily perceived stress with fertility outcomes in natural and controlled ovarian stimulation cycles: a feasibility study. J Assist Reprod Genet. 2026 Jul 24. Strohl H, Do N, Ryu H, Dayo O, Ho E, Hu J, Kauffman A, Stelzer I, Lang A, Church K, Zou J, Su I. PMID: 42498851.
      View in: PubMed   Mentions:    Fields:    
    2. Toll-like receptor 4 knockout mice are protected against PMOS-like pathogenesis. Reproduction. 2026 Jul 03; 172(1). Wiggins K, Del Mundo Z, Angulo JA, Naidu N, Saba A, Zhou L, Garcia C, Nguyen CM, Ujagar N, De La Torre JJ, De Robles G, Rivera A, Trinh D, Tinoco R, Kauffman AS, Thackray VG, Agrawal A, Seldin M, Pacheco-Sanchez G, Nicholas DA. PMID: 42384365.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    3. Surging towards a better understanding of ovulation. Elife. 2026 May 18; 15. Rose L, Kauffman AS. PMID: 42145085; PMCID: PMC13183372.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Kisspeptin made in the preoptic area is required for normal estradiol-induced LH surges and optimal fertility in females. Endocrinology. 2026 May 06; 167(6). Puffer MS, Yang J, Esparza LA, Rose L, Duong V, Radovick S, Kauffman AS. PMID: 42057695; PMCID: PMC13148160.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Haploinsufficiency of Sox2 causes fewer GnRH neurons and delayed puberty in mice. Endocrinology. 2026 01 08; 167(2). Cassin J, Dunn GA, Nguyen RD, Chen V, Duong AX, Esparza LA, Tripuraneni I, Kauffman AS, Tonsfeldt KJ, Mellon PL. PMID: 41403157; PMCID: PMC12780973.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    6. Toll-like Receptor 4 Contributes to PCOS-like Metabolic and Reproductive Pathogenesis. bioRxiv. 2025 Oct 17. Wiggins K, Del Mundo Z, Angulo JA, Naidu N, Saba A, Garcia C, Nguyen C, Ujagar N, De La Torre JJ, De Robles G, Rivera A, Trinh D, Tinoco R, Kauffman AS, Thackray VG, Agrawal A, Seldin M, Sanchez GP, Nicholas D. PMID: 41279684; PMCID: PMC12632965.
      View in: PubMed   Mentions:
    7. RFRP Neurons Are Required for Acute Stress-induced Suppression of the Estrogen-stimulated LH Surge in Female Mice. Endocrinology. 2025 Jun 10; 166(8). Evans MC, Stowe SM, Sawyer IL, Decourt C, Lee F, Kauffman AS, Anderson GM. PMID: 40488302; PMCID: PMC12206581.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. T cells are necessary for development of PCOS reproductive symptoms in a letrozole-induced mouse model of PCOS. bioRxiv. 2025 Jan 13. Ujagar N, Velez LM, De Robles G, Nguyen C, Wiggins K, Kim J, Naidu N, Angulo JA, Kauffman AS, Thackray VG, Banaszewska B, Wysocka E, Duleba A, Seldin M, Nicholas D. PMID: 39868135; PMCID: PMC11760259.
      View in: PubMed   Mentions:
    9. Selective depletion of kisspeptin neurons in the hypothalamic arcuate nucleus in early juvenile life reduces pubertal LH secretion and delays puberty onset in mice. FASEB J. 2024 10 15; 38(19):e70078. Coutinho EA, Esparza LA, Steffen PH, Liaw R, Bolleddu S, Kauffman AS. PMID: 39377760; PMCID: PMC11804785.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    10. Targeted inhibition of kisspeptin neurons reverses hyperandrogenemia and abnormal hyperactive LH secretion in a preclinical mouse model of polycystic ovary syndrome. Hum Reprod. 2024 09 01; 39(9):2089-2103. Coutinho EA, Esparza LA, Rodriguez J, Yang J, Schafer D, Kauffman AS. PMID: 38978296; PMCID: PMC11373419.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    11. Androgen Inhibition of Reproductive Neuroendocrine Function in Females and Transgender Males. Endocrinology. 2024 Aug 27; 165(10). Kauffman AS. PMID: 39207217; PMCID: PMC11393496.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    12. The molecular phenotype of kisspeptin neurons in the medial amygdala of female mice. Front Endocrinol (Lausanne). 2023; 14:1093592. Hatcher KM, Costanza L, Kauffman AS, Stephens SBZ. PMID: 36843592; PMCID: PMC9951589.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    13. Conditional Deletion of KOR (Oprk1) in Kisspeptin Cells Does Not Alter LH Pulses, Puberty, or Fertility in Mice. Endocrinology. 2022 10 23; 163(12). Coutinho EA, Esparza LA, Hudson AD, Rizo N, Steffen P, Kauffman AS. PMID: 36260530; PMCID: PMC10233252.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    14. Mistimed restricted feeding disrupts circadian rhythms of male mating behavior and female preovulatory LH surges in mice. Horm Behav. 2022 09; 145:105242. Kukino A, Walbeek TJ, Sun LJ, Watt AT, Park JH, Kauffman AS, Butler MP. PMID: 36054940; PMCID: PMC9728533.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    15. Neuroendocrine mechanisms underlying estrogen positive feedback and the LH surge. Front Neurosci. 2022; 16:953252. Kauffman AS. PMID: 35968365; PMCID: PMC9364933.
      View in: PubMed   Mentions: 32  
    16. Developmental sex differences in the peri-pubertal pattern of hypothalamic reproductive gene expression, including Kiss1 and Tac2, may contribute to sex differences in puberty onset. Mol Cell Endocrinol. 2022 07 01; 551:111654. Semaan SJ, Kauffman AS. PMID: 35469849; PMCID: PMC9889105.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    17. Kisspeptin impacts on circadian and ultradian rhythms of core body temperature: Evidence in kisspeptin receptor knockout and kisspeptin knockdown mice. Mol Cell Endocrinol. 2022 02 15; 542:111530. Kavanagh GS, Tadi J, Balkenhol SM, Kauffman AS, Maloney SK, Smith JT. PMID: 34896241; PMCID: PMC9907773.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    18. Progesterone Receptors in AVPV Kisspeptin Neurons Are Sufficient for Positive Feedback Induction of the LH Surge. Endocrinology. 2021 11 01; 162(11). Mohr MA, Esparza LA, Steffen P, Micevych PE, Kauffman AS. PMID: 34379733; PMCID: PMC8423423.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    19. Metabolic actions of kisspeptin signaling: Effects on body weight, energy expenditure, and feeding. Pharmacol Ther. 2022 03; 231:107974. Hudson AD, Kauffman AS. PMID: 34530008; PMCID: PMC8884343.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    20. Estrogen Regulation of the Molecular Phenotype and Active Translatome of AVPV Kisspeptin Neurons. Endocrinology. 2021 09 01; 162(9). Stephens SBZ, Kauffman AS. PMID: 33856454; PMCID: PMC8286094.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    21. Androgen Suppresses In Vivo and In Vitro LH Pulse Secretion and Neural Kiss1 and Tac2 Gene Expression in Female Mice. Endocrinology. 2020 12 01; 161(12). Esparza LA, Terasaka T, Lawson MA, Kauffman AS. PMID: 33075809; PMCID: PMC7671291.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    22. GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes. Sci Rep. 2020 08 03; 10(1):13063. Nicholas DA, Knight VS, Tonsfeldt KJ, Terasaka T, Molinar-Inglis O, Stephens SBZ, Trejo J, Kauffman AS, Mellon PL, Lawson MA. PMID: 32747664; PMCID: PMC7400764.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    23. Hyperactive LH Pulses and Elevated Kisspeptin and NKB Gene Expression in the Arcuate Nucleus of a PCOS Mouse Model. Endocrinology. 2020 04 01; 161(4). Esparza LA, Schafer D, Ho BS, Thackray VG, Kauffman AS. PMID: 32031594; PMCID: PMC7341557.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    24. Editorial: Hormone release patterns in mammals. Mol Cell Endocrinol. 2020 05 01; 507:110781. Kauffman AS, Hoffmann HM. PMID: 32119896; PMCID: PMC7880580.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    25. Conditional knockout of kisspeptin signaling in brown adipose tissue increases metabolic rate and body temperature and lowers body weight. FASEB J. 2020 01; 34(1):107-121. Tolson KP, Marooki N, De Bond JP, Walenta E, Stephens SBZ, Liaw RB, Savur R, Wolfe A, Oh DY, Smith JT, Kauffman AS. PMID: 31914628; PMCID: PMC7202476.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    26. Potential use of stem cells for fertility preservation. Andrology. 2020 07; 8(4):862-878. Gauthier-Fisher A, Kauffman A, Librach CL. PMID: 31560823.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    27. Neural and endocrine mechanisms underlying stress-induced suppression of pulsatile LH secretion. Mol Cell Endocrinol. 2019 12 01; 498:110579. McCosh RB, Breen KM, Kauffman AS. PMID: 31521706; PMCID: PMC6874223.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    28. Cre/lox generation of a novel whole-body Kiss1r KO mouse line recapitulates a hypogonadal, obese, and metabolically-impaired phenotype. Mol Cell Endocrinol. 2019 12 01; 498:110559. Tolson KP, Marooki N, Wolfe A, Smith JT, Kauffman AS. PMID: 31442544; PMCID: PMC6814569.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    29. The Role of the Brain in the Pathogenesis and Physiology of Polycystic Ovary Syndrome (PCOS). Med Sci (Basel). 2019 Aug 02; 7(8). Coutinho EA, Kauffman AS. PMID: 31382541; PMCID: PMC6722593.
      View in: PubMed   Mentions: 45     Fields:    
    30. Stress rapidly suppresses in vivo LH pulses and increases activation of RFRP-3 neurons in male mice J Endocrinol. 2018 10 31; 239(3):339-350. Yang JA, Hughes JK, Parra RA, Volk KM, Kauffman AS. PMID: 30382693; PMCID: PMC6214202.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    31. Estradiol-Dependent and -Independent Stimulation of Kiss1 Expression in the Amygdala, BNST, and Lateral Septum of Mice. Endocrinology. 2018 09 01; 159(9):3389-3402. Stephens SBZ, Di Giorgio NP, Liaw RB, Parra RA, Yang JA, Chahal N, Lux-Lantos VA, Kauffman AS. PMID: 30107405; PMCID: PMC6112601.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    32. Emerging insights into hypothalamic-pituitary-gonadal axis regulation and interaction with stress signalling. J Neuroendocrinol. 2018 10; 30(10):e12590. Acevedo-Rodriguez A, Kauffman AS, Cherrington BD, Borges CS, Roepke TA, Laconi M. PMID: 29524268; PMCID: PMC6129417.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimals
    33. The 3rd World Conference on Kisspeptin, "Kisspeptin 2017: Brain and Beyond":Unresolved questions, challenges and future directions for the field. J Neuroendocrinol. 2018 Apr 14; e12600. Lehman MN, Coolen LM, Steiner RA, Neal-Perry G, Wang L, Moenter SM, Moore AM, Goodman RL, Hwa-Yeo S, Padilla SL, Kauffman AS, Garcia J, Kelly MJ, Clarkson J, Radovick S, Babwah AV, Leon S, Tena-Sempere M, Comninos A, Seminara S, Dhillo WS, Levine J, Terasawa E, Negron A, Herbison AE. PMID: 29656508; PMCID: PMC6461527.
      View in: PubMed   Mentions: 3     Fields:    
    34. Acute Psychosocial Stress Inhibits LH Pulsatility and Kiss1 Neuronal Activation in Female Mice. Endocrinology. 2017 11 01; 158(11):3716-3723. Yang JA, Song CI, Hughes JK, Kreisman MJ, Parra RA, Haisenleder DJ, Kauffman AS, Breen KM. PMID: 28973125; PMCID: PMC5695836.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    35. Sex Differences in Steroid Receptor Coexpression and Circadian-Timed Activation of Kisspeptin and RFRP-3 Neurons May Contribute to the Sexually Dimorphic Basis of the LH Surge. Endocrinology. 2017 10 01; 158(10):3565-3578. Poling MC, Luo EY, Kauffman AS. PMID: 28938464; PMCID: PMC5659694.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    36. Regulation and Possible Functions of Kisspeptin in the Medial Amygdala. Front Endocrinol (Lausanne). 2017; 8:191. Stephens SBZ, Kauffman AS. PMID: 28824550; PMCID: PMC5545938.
      View in: PubMed   Mentions: 13     Fields:    
    37. Effects of Selective Deletion of Tyrosine Hydroxylase from Kisspeptin Cells on Puberty and Reproduction in Male and Female Mice. eNeuro. 2017 May-Jun; 4(3). Stephens SBZ, Rouse ML, Tolson KP, Liaw RB, Parra RA, Chahal N, Kauffman AS. PMID: 28660243; PMCID: PMC5480141.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    38. Bmal1 Is Required for Normal Reproductive Behaviors in Male Mice. Endocrinology. 2016 Dec; 157(12):4914-4929. Schoeller EL, Clark DD, Dey S, Cao NV, Semaan SJ, Chao LW, Kauffman AS, Stowers L, Mellon PL. PMID: 27704948; PMCID: PMC5133342.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    39. Unaltered Hypothalamic Metabolic Gene Expression in Kiss1r Knockout Mice Despite Obesity and Reduced Energy Expenditure. J Neuroendocrinol. 2016 10; 28(10). De Bond JP, Tolson KP, Nasamran C, Kauffman AS, Smith JT. PMID: 27601011; PMCID: PMC5083214.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    40. Metabolism and Energy Expenditure, But Not Feeding or Glucose Tolerance, Are Impaired in Young Kiss1r KO Female Mice. Endocrinology. 2016 Nov; 157(11):4192-4199. Tolson KP, Garcia C, Delgado I, Marooki N, Kauffman AS. PMID: 27649089; PMCID: PMC5086529.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    41. Estrogen Stimulation of Kiss1 Expression in the Medial Amygdala Involves Estrogen Receptor-α But Not Estrogen Receptor-β. Endocrinology. 2016 Oct; 157(10):4021-4031. Stephens SB, Chahal N, Munaganuru N, Parra RA, Kauffman AS. PMID: 27564649; PMCID: PMC5045512.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    42. Corticosterone Blocks Ovarian Cyclicity and the LH Surge via Decreased Kisspeptin Neuron Activation in Female Mice. Endocrinology. 2016 Mar; 157(3):1187-99. Luo E, Stephens SB, Chaing S, Munaganuru N, Kauffman AS, Breen KM. PMID: 26697722; PMCID: PMC4769373.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    43. Regulation and Function of RFRP-3 (GnIH) Neurons during Postnatal Development. Front Endocrinol (Lausanne). 2015; 6:150. Poling MC, Kauffman AS. PMID: 26441840; PMCID: PMC4585233.
      View in: PubMed   Mentions: 12     Fields:    
    44. A Novel Letrozole Model Recapitulates Both the Reproductive and Metabolic Phenotypes of Polycystic Ovary Syndrome in Female Mice. Biol Reprod. 2015 Sep; 93(3):69. Kauffman AS, Thackray VG, Ryan GE, Tolson KP, Glidewell-Kenney CA, Semaan SJ, Poling MC, Iwata N, Breen KM, Duleba AJ, Stener-Victorin E, Shimasaki S, Webster NJ, Mellon PL. PMID: 26203175; PMCID: PMC4710190.
      View in: PubMed   Mentions: 105     Fields:    Translation:Animals
    45. Absent Progesterone Signaling in Kisspeptin Neurons Disrupts the LH Surge and Impairs Fertility in Female Mice. Endocrinology. 2015 Sep; 156(9):3091-7. Stephens SB, Tolson KP, Rouse ML, Poling MC, Hashimoto-Partyka MK, Mellon PL, Kauffman AS. PMID: 26076042; PMCID: PMC4541622.
      View in: PubMed   Mentions: 60     Fields:    Translation:Animals
    46. Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice. Mol Cell Endocrinol. 2015 Aug 15; 411:223-31. Xie C, Jonak CR, Kauffman AS, Coss D. PMID: 25958044; PMCID: PMC4764054.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    47. Circadian Control of the Female Reproductive Axis Through Gated Responsiveness of the RFRP-3 System to VIP Signaling. Endocrinology. 2015 Jul; 156(7):2608-18. Russo KA, La JL, Stephens SB, Poling MC, Padgaonkar NA, Jennings KJ, Piekarski DJ, Kauffman AS, Kriegsfeld LJ. PMID: 25872006; PMCID: PMC4475714.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    48. Daily successive changes in reproductive gene expression and neuronal activation in the brains of pubertal female mice. Mol Cell Endocrinol. 2015 Feb 05; 401:84-97. Semaan SJ, Kauffman AS. PMID: 25498961; PMCID: PMC4312730.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    49. Examination of the influence of leptin and acute metabolic challenge on RFRP-3 neurons of mice in development and adulthood. Neuroendocrinology. 2014; 100(4):317-33. Poling MC, Shieh MP, Munaganuru N, Luo E, Kauffman AS. PMID: 25378037; PMCID: PMC4329049.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    50. Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice. Endocrinology. 2014 Oct; 155(10):4043-53. Hoffmann HM, Tamrazian A, Xie H, Pérez-Millán MI, Kauffman AS, Mellon PL. PMID: 25060364; PMCID: PMC4164932.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    51. Primary cilia enhance kisspeptin receptor signaling on gonadotropin-releasing hormone neurons. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10335-40. Koemeter-Cox AI, Sherwood TW, Green JA, Steiner RA, Berbari NF, Yoder BK, Kauffman AS, Monsma PC, Brown A, Askwith CC, Mykytyn K. PMID: 24982149; PMCID: PMC4104922.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    52. Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity. J Clin Invest. 2014 Jul; 124(7):3075-9. Tolson KP, Garcia C, Yen S, Simonds S, Stefanidis A, Lawrence A, Smith JT, Kauffman AS. PMID: 24937427; PMCID: PMC4071390.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    53. Vasoactive intestinal peptide modulation of the steroid-induced LH surge involves kisspeptin signaling in young but not in middle-aged female rats. Endocrinology. 2014 Jun; 155(6):2222-32. Kauffman AS, Sun Y, Kim J, Khan AR, Shu J, Neal-Perry G. PMID: 24654782; PMCID: PMC4020928.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    54. Impaired GABAB receptor signaling dramatically up-regulates Kiss1 expression selectively in nonhypothalamic brain regions of adult but not prepubertal mice. Endocrinology. 2014 Mar; 155(3):1033-44. Di Giorgio NP, Semaan SJ, Kim J, López PV, Bettler B, Libertun C, Lux-Lantos VA, Kauffman AS. PMID: 24424047; PMCID: PMC3929734.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    55. Lack of functional GABAB receptors alters Kiss1 , Gnrh1 and Gad1 mRNA expression in the medial basal hypothalamus at postnatal day 4. Neuroendocrinology. 2013; 98(3):212-23. Di Giorgio NP, Catalano PN, López PV, González B, Semaan SJ, López GC, Kauffman AS, Rulli SB, Somoza GM, Bettler B, Libertun C, Lux-Lantos VA. PMID: 24080944; PMCID: PMC3915412.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    56. Kisspeptin neurones do not directly signal to RFRP-3 neurones but RFRP-3 may directly modulate a subset of hypothalamic kisspeptin cells in mice. J Neuroendocrinol. 2013 Oct; 25(10):876-86. Poling MC, Quennell JH, Anderson GM, Kauffman AS. PMID: 23927071; PMCID: PMC4022484.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    57. Developmental GnRH signaling is not required for sexual differentiation of kisspeptin neurons but is needed for maximal Kiss1 gene expression in adult females. Endocrinology. 2013 Sep; 154(9):3273-83. Kim J, Tolson KP, Dhamija S, Kauffman AS. PMID: 23825121; PMCID: PMC3749477.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    58. Kisspeptin regulates gonadotropin genes via immediate early gene induction in pituitary gonadotropes. Mol Endocrinol. 2013 Aug; 27(8):1283-94. Witham EA, Meadows JD, Hoffmann HM, Shojaei S, Coss D, Kauffman AS, Mellon PL. PMID: 23770611; PMCID: PMC3725344.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    59. Analysis of multiple positive feedback paradigms demonstrates a complete absence of LH surges and GnRH activation in mice lacking kisspeptin signaling. Biol Reprod. 2013 Jun; 88(6):146. Dror T, Franks J, Kauffman AS. PMID: 23595904; PMCID: PMC4070868.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    60. Emerging concepts on the epigenetic and transcriptional regulation of the Kiss1 gene. Int J Dev Neurosci. 2013 Oct; 31(6):452-62. Semaan SJ, Kauffman AS. PMID: 23510953; PMCID: PMC3703475.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    61. The development of kisspeptin circuits in the Mammalian brain. Adv Exp Med Biol. 2013; 784:221-52. Semaan SJ, Tolson KP, Kauffman AS. PMID: 23550009; PMCID: PMC4305450.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    62. Prenatal exposure to low levels of androgen accelerates female puberty onset and reproductive senescence in mice. Endocrinology. 2012 Sep; 153(9):4522-32. Witham EA, Meadows JD, Shojaei S, Kauffman AS, Mellon PL. PMID: 22778229; PMCID: PMC3423623.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    63. Organizational and activational effects of sex steroids on kisspeptin neuron development. Front Neuroendocrinol. 2013 Jan; 34(1):3-17. Poling MC, Kauffman AS. PMID: 22728025; PMCID: PMC3725275.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    64. RFamide-related peptide-3 receptor gene expression in GnRH and kisspeptin neurons and GnRH-dependent mechanism of action. Endocrinology. 2012 Aug; 153(8):3770-9. Rizwan MZ, Poling MC, Corr M, Cornes PA, Augustine RA, Quennell JH, Kauffman AS, Anderson GM. PMID: 22691552.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    65. Assessment of epigenetic contributions to sexually-dimorphic Kiss1 expression in the anteroventral periventricular nucleus of mice. Endocrinology. 2012 Apr; 153(4):1875-86. Semaan SJ, Dhamija S, Kim J, Ku EC, Kauffman AS. PMID: 22374971; PMCID: PMC3320252.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    66. Development, sex steroid regulation, and phenotypic characterization of RFamide-related peptide (Rfrp) gene expression and RFamide receptors in the mouse hypothalamus. Endocrinology. 2012 Apr; 153(4):1827-40. Poling MC, Kim J, Dhamija S, Kauffman AS. PMID: 22355072; PMCID: PMC3320244.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    67. The role of kisspeptin and RFamide-related peptide-3 neurones in the circadian-timed preovulatory luteinising hormone surge. J Neuroendocrinol. 2012 Jan; 24(1):131-43. Khan AR, Kauffman AS. PMID: 21592236; PMCID: PMC3384704.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    68. Sexually dimorphic testosterone secretion in prenatal and neonatal mice is independent of kisspeptin-Kiss1r and GnRH signaling. Endocrinology. 2012 Feb; 153(2):782-93. Poling MC, Kauffman AS. PMID: 22202164; PMCID: PMC3275395.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    69. Regulation of Kiss1 expression by sex steroids in the amygdala of the rat and mouse. Endocrinology. 2011 May; 152(5):2020-30. Kim J, Semaan SJ, Clifton DK, Steiner RA, Dhamija S, Kauffman AS. PMID: 21363930; PMCID: PMC3075940.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    70. BAX-dependent and BAX-independent regulation of Kiss1 neuron development in mice. Endocrinology. 2010 Dec; 151(12):5807-17. Semaan SJ, Murray EK, Poling MC, Dhamija S, Forger NG, Kauffman AS. PMID: 20926580; PMCID: PMC2999490.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    71. Sexual differentiation and development of forebrain reproductive circuits. Curr Opin Neurobiol. 2010 Aug; 20(4):424-31. Semaan SJ, Kauffman AS. PMID: 20471241; PMCID: PMC2937059.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    72. Gonadal and nongonadal regulation of sex differences in hypothalamic Kiss1 neurones. J Neuroendocrinol. 2010 Jul; 22(7):682-91. Kauffman AS. PMID: 20492362; PMCID: PMC3096441.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    73. Pelage insulation, litter size, and ambient temperature impact maternal energy intake and offspring development during lactation. Physiol Behav. 2010 May 11; 100(2):128-34. Paul MJ, Tuthill C, Kauffman AS, Zucker I. PMID: 20184907; PMCID: PMC2886721.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    74. Coming of age in the kisspeptin era: sex differences, development, and puberty. Mol Cell Endocrinol. 2010 Aug 05; 324(1-2):51-63. Kauffman AS. PMID: 20083160; PMCID: PMC2902563.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    75. Critical periods of susceptibility to short-term energy challenge during pregnancy: Impact on fertility and offspring development. Physiol Behav. 2010 Jan 12; 99(1):100-8. Kauffman AS, Bojkowska K, Rissman EF. PMID: 19891981; PMCID: PMC2795402.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    76. Sex differences in the regulation of Kiss1/NKB neurons in juvenile mice: implications for the timing of puberty. Am J Physiol Endocrinol Metab. 2009 Nov; 297(5):E1212-21. Kauffman AS, Navarro VM, Kim J, Clifton DK, Steiner RA. PMID: 19755669; PMCID: PMC2781353.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    77. Circadian regulation of Kiss1 neurons: implications for timing the preovulatory gonadotropin-releasing hormone/luteinizing hormone surge. Endocrinology. 2009 Aug; 150(8):3664-71. Robertson JL, Clifton DK, de la Iglesia HO, Steiner RA, Kauffman AS. PMID: 19443569; PMCID: PMC2717859.
      View in: PubMed   Mentions: 106     Fields:    Translation:AnimalsCells
    78. Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation. J Neurosci. 2009 Mar 25; 29(12):3920-9. Roseweir AK, Kauffman AS, Smith JT, Guerriero KA, Morgan K, Pielecka-Fortuna J, Pineda R, Gottsch ML, Tena-Sempere M, Moenter SM, Terasawa E, Clarke IJ, Steiner RA, Millar RP. PMID: 19321788; PMCID: PMC3035813.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    79. Sexual differentiation and the Kiss1 system: hormonal and developmental considerations. Peptides. 2009 Jan; 30(1):83-93. Kauffman AS. PMID: 18644414; PMCID: PMC2631352.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    80. Emerging ideas about kisspeptin- GPR54 signaling in the neuroendocrine regulation of reproduction. Trends Neurosci. 2007 Oct; 30(10):504-11. Kauffman AS, Clifton DK, Steiner RA. PMID: 17904653.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimalsCells
    81. The kisspeptin receptor GPR54 is required for sexual differentiation of the brain and behavior. J Neurosci. 2007 Aug 15; 27(33):8826-35. Kauffman AS, Park JH, McPhie-Lalmansingh AA, Gottsch ML, Bodo C, Hohmann JG, Pavlova MN, Rohde AD, Clifton DK, Steiner RA, Rissman EF. PMID: 17699664; PMCID: PMC6672184.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    82. Sexual differentiation of Kiss1 gene expression in the brain of the rat. Endocrinology. 2007 Apr; 148(4):1774-83. Kauffman AS, Gottsch ML, Roa J, Byquist AC, Crown A, Clifton DK, Hoffman GE, Steiner RA, Tena-Sempere M. PMID: 17204549.
      View in: PubMed   Mentions: 206     Fields:    Translation:Animals
    83. Interval timer control of puberty in photoinhibited Siberian hamsters. J Biol Rhythms. 2006 Oct; 21(5):373-83. Park JH, Kauffman AS, Paul MJ, Butler MP, Beery AK, Costantini RM, Zucker I. PMID: 16998157.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    84. Gonadotropin-releasing hormone-II messenger ribonucleic acid and protein content in the mammalian brain are modulated by food intake. Endocrinology. 2006 Nov; 147(11):5069-77. Kauffman AS, Bojkowska K, Wills A, Rissman EF. PMID: 16873537.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    85. Role of gonadotropin-releasing hormone II in the mammalian nervous system. Expert Rev Endocrinol Metab. 2006 Jan; 1(1):133-145. Kauffman AS, Rissman EF. PMID: 30743776.
      View in: PubMed   Mentions: 1     Fields:    
    86. Evidence that the type-2 gonadotrophin-releasing hormone (GnRH) receptor mediates the behavioural effects of GnRH-II on feeding and reproduction in musk shrews. J Neuroendocrinol. 2005 Aug; 17(8):489-97. Kauffman AS, Wills A, Millar RP, Rissman EF. PMID: 16011485.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    87. Effects of galanin-like peptide (GALP) on locomotion, reproduction, and body weight in female and male mice. Horm Behav. 2005 Aug; 48(2):141-51. Kauffman AS, Buenzle J, Fraley GS, Rissman EF. PMID: 16042964.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    88. Emerging functions of gonadotropin-releasing hormone II in mammalian physiology and behaviour. J Neuroendocrinol. 2004 Sep; 16(9):794-806. Kauffman AS. PMID: 15344918.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    89. Reduced leptin concentrations are permissive for display of torpor in Siberian hamsters. Am J Physiol Regul Integr Comp Physiol. 2004 Jul; 287(1):R97-R103. Freeman DA, Lewis DA, Kauffman AS, Blum RM, Dark J. PMID: 15191926.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    90. Feeding schedule controls circadian timing of daily torpor in SCN-ablated Siberian hamsters. J Biol Rhythms. 2004 Jun; 19(3):226-37. Paul MJ, Kauffman AS, Zucker I. PMID: 15155009.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    91. A critical role for the evolutionarily conserved gonadotropin-releasing hormone II: mediation of energy status and female sexual behavior. Endocrinology. 2004 Aug; 145(8):3639-46. Kauffman AS, Rissman EF. PMID: 15105381.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    92. Increased heat loss affects hibernation in golden-mantled ground squirrels. Am J Physiol Regul Integr Comp Physiol. 2004 Jul; 287(1):R167-73. Kauffman AS, Paul MJ, Zucker I. PMID: 15016623.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    93. The evolutionarily conserved gonadotropin-releasing hormone II modifies food intake. Endocrinology. 2004 Feb; 145(2):686-91. Kauffman AS, Rissman EF. PMID: 14576176.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    94. Huddling, locomotor, and nest-building behaviors of furred and furless Siberian hamsters. Physiol Behav. 2003 Jul; 79(2):247-56. Kauffman AS, Paul MJ, Butler MP, Zucker I. PMID: 12834796.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    95. Termination of neuroendocrine refractoriness to melatonin in Siberian hamsters (Phodopus sungorus). J Neuroendocrinol. 2003 Feb; 15(2):191-6. Kauffman AS, Freeman DA, Zucker I. PMID: 12535161.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    96. Testicular recrudescence in intermediate day lengths reflects loss of photoperiodic memory in Siberian hamsters. J Biol Rhythms. 2002 Aug; 17(4):345-52. Kauffman AS, Zucker I. PMID: 12164250.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    97. Torpor characteristics and energy requirements of furless Siberian hamsters. Physiol Biochem Zool. 2001 Nov-Dec; 74(6):876-84. Kauffman AS, Cabrera A, Zucker I. PMID: 11731979.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    98. Energy intake and fur in summer- and winter-acclimated Siberian hamsters (Phodopus sungorus). Am J Physiol Regul Integr Comp Physiol. 2001 Aug; 281(2):R519-27. Kauffman AS, Cabrera A, Zucker I. PMID: 11448856.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
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