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Victor De Gruttola

Title(s)Adjunct Professor, Herbert Wertheim School of Public Health & Human Longevity Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Salvaging information from paused or stopped clinical studies. Clin Trials. 2025 Jul 12; 17407745251353429. Smith D, Fleming T, Gianella S, Halloran E, Hillier S, Longini I, Smeaton L, DeGruttola V. PMID: 40650496; PMCID: PMC12331140.
      View in: PubMed   Mentions:    Fields:    
    2. Machine Learning and Probabilistic Approaches for Forecasting COVID-19 Transmission and Cases. medRxiv. 2025 Jun 24. Hossain MS, Goyal R, Martin NK, DeGruttola V, Ahammed T, McMahan C, Rennert L. PMID: 40666366; PMCID: PMC12262794.
      View in: PubMed   Mentions:
    3. A flexible framework for local-level estimation of the effective reproductive number in geographic regions with sparse data. BMC Med Res Methodol. 2025 Mar 18; 25(1):73. Hossain MS, Goyal R, Martin NK, DeGruttola V, Chowdhury MM, McMahan C, Rennert L. PMID: 40102783; PMCID: PMC11917005.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    4. A Flexible Framework for Local-Level Estimation of the Effective Reproductive Number in Geographic Regions with Sparse Data. medRxiv. 2025 Mar 10. Hossain MS, Goyal R, Martin NK, DeGruttola V, Chowdhury MM, McMahan C, Rennert L. PMID: 40162254; PMCID: PMC11952488.
      View in: PubMed   Mentions:
    5. Cytokine trajectory over time in men and women with HIV on long-term antiretroviral therapy. AIDS. 2025 Jan 01; 39(1):1-10. Vanpouille C, Wells A, DeGruttola V, Lynch M, Zhang X, Fitzgerald W, Tu X, Chaillon A, Landay A, Weber K, Scully E, Karn J, Gianella S. PMID: 39639719; PMCID: PMC11631044.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Letter to editor regarding: "Moral controversies and academic public health: Notes on navigating and surviving academic freedom challenges" by professor VanderWeele. Glob Epidemiol. 2024 Dec; 8:100152. Litwack R, DeGruttola V. PMID: 39070696; PMCID: PMC11283073.
      View in: PubMed   Mentions: 1  
    7. Designing and analyzing studies of coronavirus disease 2019 and post-acute sequelae of severe acute respiratory syndrome coronavirus 2 among immunocompromised individuals. Transpl Infect Dis. 2024 Apr; 26(2):e14231. DeGruttola V, Aslam S. PMID: 38375954; PMCID: PMC11009066.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Post-acute sequelae of COVID-19 in solid organ transplant recipients. Transpl Infect Dis. 2023 Dec; 25(6):e14167. Sigler R, Covarrubias K, Chen B, Rubarth RB, Torosian K, Sanchez CR, Bharti A, DeGruttola V, Aslam S. PMID: 37922371; PMCID: PMC10841400.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Modeling homophily in dynamic networks with application to HIV molecular surveillance. BMC Infect Dis. 2023 Oct 04; 23(1):656. DeGruttola V, Nakazawa M, Lin T, Liu J, Goyal R, Little S, Tu X, Mehta S. PMID: 37794364; PMCID: PMC10548762.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Leveraging Contact Network Information in Clustered Randomized Studies of Contagion Processes. Obs Stud. 2023; 9(2):157-175. Wang MH, Staples P, Prague M, Goyal R, DeGruttola V, Onnela JP. PMID: 37325081; PMCID: PMC10270696.
      View in: PubMed   Mentions: 3  
    11. Network methods and design of randomized trials: Application to investigation of COVID-19 vaccination boosters. Clin Trials. 2022 08; 19(4):363-374. DeGruttola V, Goyal R, Martin NK, Wang R. PMID: 35894099; PMCID: PMC9378506.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    12. Ensemble clustering of longitudinal bivariate HIV biomarker profiles to group patients by patterns of disease progression. Int J Data Sci Anal. 2022; 14(3):305-318. Lynch ML, DeGruttola V. PMID: 35528805; PMCID: PMC9064718.
      View in: PubMed   Mentions:
    13. Deep-sequence phylogenetics to quantify patterns of HIV transmission in the context of a universal testing and treatment trial - BCPP/Ya Tsie trial. Elife. 2022 03 01; 11. Magosi LE, Zhang Y, Golubchik T, DeGruttola V, Tchetgen Tchetgen E, Novitsky V, Moore J, Bachanas P, Segolodi T, Lebelonyane R, Pretorius Holme M, Moyo S, Makhema J, Lockman S, Fraser C, Essex MM, Lipsitch M, Botswana Combination Prevention Project and PANGEA consortium. PMID: 35229714; PMCID: PMC8912920.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansPHPublic Health
    14. Effective Human Immunodeficiency Virus Molecular Surveillance Requires Identification of Incident Cases of Infection. Clin Infect Dis. 2021 09 07; 73(5):842-849. Little SJ, Chen T, Wang R, Anderson C, Pond SK, Nakazawa M, Mathews WC, DeGruttola V, Smith DM. PMID: 34492694; PMCID: PMC8423467.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsPHPublic Health
    15. Bayesian reconstruction of transmission trees from genetic sequences and uncertain infection times. Stat Appl Genet Mol Biol. 2020 Oct 21. Montazeri H, Little S, Mozaffarilegha M, Beerenwinkel N, DeGruttola V. PMID: 33085643; PMCID: PMC8212962.
      View in: PubMed   Mentions: 3     Fields:    
    16. The vitamin D for COVID-19 (VIVID) trial: A pragmatic cluster-randomized design. Contemp Clin Trials. 2021 01; 100:106176. Wang R, DeGruttola V, Lei Q, Mayer KH, Redline S, Hazra A, Mora S, Willett WC, Ganmaa D, Manson JE. PMID: 33045402; PMCID: PMC7547023.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCellsCTClinical Trials
    17. Efficient estimation of human immunodeficiency virus incidence rate using a pooled cross-sectional cohort study design. Stat Med. 2020 10 30; 39(24):3255-3271. Molebatsi K, Gabaitiri L, Mokgatlhe L, Moyo S, Gaseitsiwe S, Wirth KE, DeGruttola V, Tchetgen Tchetgen E. PMID: 32875624; PMCID: PMC8118390.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    18. Bayesian method for inferring the impact of geographical distance on intensity of communication. Sci Rep. 2020 07 16; 10(1):11775. Ozga F, Onnela JP, DeGruttola V. PMID: 32678148; PMCID: PMC7367279.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    19. Mapping of HIV-1C Transmission Networks Reveals Extensive Spread of Viral Lineages Across Villages in Botswana Treatment-as-Prevention Trial. J Infect Dis. 2020 11 15; 222(10):1670-1680. Novitsky V, Zahralban-Steele M, Moyo S, Nkhisang T, Maruapula D, McLane MF, Leidner J, Bennett K, PANGEA Consortium, Wirth KE, Gaolathe T, Kadima E, Chakalisa U, Pretorius Holme M, Lockman S, Mmalane M, Makhema J, Gaseitsiwe S, DeGruttola V, Essex M. PMID: 32492145; PMCID: PMC7936922.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    20. Population uptake of HIV testing, treatment, viral suppression, and male circumcision following a community-based intervention in Botswana (Ya Tsie/BCPP): a cluster-randomised trial. Lancet HIV. 2020 06; 7(6):e422-e433. Wirth KE, Gaolathe T, Pretorius Holme M, Mmalane M, Kadima E, Chakalisa U, Manyake K, Matildah Mbikiwa A, Simon SV, Letlhogile R, Mukokomani K, van Widenfelt E, Moyo S, Bennett K, Leidner J, Powis KM, Lebelonyane R, Alwano MG, Jarvis J, Dryden-Peterson SL, Kgathi C, Moore J, Bachanas P, Raizes E, Abrams W, Block L, Sento B, Novitsky V, El-Halabi S, Marukutira T, Mills LA, Sexton C, Pals S, Shapiro RL, Wang R, Lei Q, DeGruttola V, Makhema J, Essex M, Lockman S, Tchetgen Tchetgen EJ. PMID: 32504575; PMCID: PMC7864245.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsPHPublic Health
    21. A flexible nonlinear mixed effects model for HIV viral load rebound after treatment interruption. Stat Med. 2020 07 10; 39(15):2051-2066. Wang R, Bing A, Wang C, Hu Y, Bosch RJ, DeGruttola V. PMID: 32293756; PMCID: PMC8081565.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    22. Bottom-up and top-down neural signatures of disordered multi-talker speech perception in adults with normal hearing. Elife. 2020 01 21; 9. Parthasarathy A, Hancock KE, Bennett K, DeGruttola V, Polley DB. PMID: 31961322; PMCID: PMC6974362.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    23. Universal Testing, Expanded Treatment, and Incidence of HIV Infection in Botswana. N Engl J Med. 2019 07 18; 381(3):230-242. Makhema J, Wirth KE, Pretorius Holme M, Gaolathe T, Mmalane M, Kadima E, Chakalisa U, Bennett K, Leidner J, Manyake K, Mbikiwa AM, Simon SV, Letlhogile R, Mukokomani K, van Widenfelt E, Moyo S, Lebelonyane R, Alwano MG, Powis KM, Dryden-Peterson SL, Kgathi C, Novitsky V, Moore J, Bachanas P, Abrams W, Block L, El-Halabi S, Marukutira T, Mills LA, Sexton C, Raizes E, Gaseitsiwe S, Bussmann H, Okui L, John O, Shapiro RL, Pals S, Michael H, Roland M, DeGruttola V, Lei Q, Wang R, Tchetgen Tchetgen E, Essex M, Lockman S. PMID: 31314967; PMCID: PMC6800102.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansPHPublic Health
    24. Designing & Conducting Trials To Reliably Evaluate HIV Prevention Interventions. Stat Commun Infect Dis. 2019; 11(1). Fleming TR, DeGruttola V, Donnell D. PMID: 33777327; PMCID: PMC7996711.
      View in: PubMed   Mentions:
    25. Short Communication: Viral Genetic Linkage Analysis Among Black Men Who Have Sex With Men (HIV Prevention Trials Network 061). AIDS Res Hum Retroviruses. 2019 05; 35(5):434-436. Kobe J, Talbot O, Chen I, Eshleman SH, Cummings V, Wheeler D, Mayer KH, DeGruttola V. PMID: 30638029; PMCID: PMC6508062.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    26. Simulations for designing and interpreting intervention trials in infectious diseases. BMC Med. 2017 12 29; 15(1):223. Halloran ME, Auranen K, Baird S, Basta NE, Bellan SE, Brookmeyer R, Cooper BS, DeGruttola V, Hughes JP, Lessler J, Lofgren ET, Longini IM, Onnela JP, Özler B, Seage GR, Smith TA, Vespignani A, Vynnycky E, Lipsitch M. PMID: 29287587; PMCID: PMC5747936.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    27. Estimating mono- and bi-phasic regression parameters using a mixture piecewise linear Bayesian hierarchical model. PLoS One. 2017; 12(7):e0180756. Zhao R, Catalano P, DeGruttola VG, Michor F. PMID: 28723910; PMCID: PMC5516991.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    28. Using a network-based approach and targeted maximum likelihood estimation to evaluate the effect of adding pre-exposure prophylaxis to an ongoing test-and-treat trial. Clin Trials. 2017 Apr; 14(2):201-210. Balzer L, Staples P, Onnela JP, DeGruttola V. PMID: 28124579; PMCID: PMC5377920.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    29. Can the Heterosexual HIV Epidemic be Eliminated in South Africa Using Combination Prevention? A Modeling Analysis. Am J Epidemiol. 2016 08 01; 184(3):239-48. Abuelezam NN, McCormick AW, Fussell T, Afriyie AN, Wood R, DeGruttola V, Freedberg KA, Lipsitch M, Seage GR. PMID: 27416841; PMCID: PMC4967594.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic Health
    30. Accounting for interactions and complex inter-subject dependency in estimating treatment effect in cluster-randomized trials with missing outcomes. Biometrics. 2016 12; 72(4):1066-1077. Prague M, Wang R, Stephens A, Tchetgen Tchetgen E, DeGruttola V. PMID: 27060877; PMCID: PMC5055852.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    31. Botswana's progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals: a population-based survey. Lancet HIV. 2016 May; 3(5):e221-30. Gaolathe T, Wirth KE, Holme MP, Makhema J, Moyo S, Chakalisa U, Yankinda EK, Lei Q, Mmalane M, Novitsky V, Okui L, van Widenfelt E, Powis KM, Khan N, Bennett K, Bussmann H, Dryden-Peterson S, Lebelonyane R, El-Halabi S, Mills LA, Marukutira T, Wang R, Tchetgen EJ, DeGruttola V, Essex M, Lockman S, Botswana Combination Prevention Project study team. PMID: 27126489; PMCID: PMC5146754.
      View in: PubMed   Mentions: 148     Fields:    Translation:Humans
    32. A composite likelihood approach for estimating HIV prevalence in the presence of spatial variation. Stat Med. 2015 Dec 10; 34(28):3750-9. Wirth KE, Agniel D, Barr CD, Austin MD, DeGruttola V. PMID: 26215657; PMCID: PMC5029272.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    33. Estimated age and gender profile of individuals missed by a home-based HIV testing and counselling campaign in a Botswana community. J Int AIDS Soc. 2015; 18:19918. Novitsky V, Bussmann H, Okui L, Logan A, Moyo S, van Widenfelt E, Mmalane M, Lei Q, Holme MP, Makhema J, Lockman S, Degruttola V, Essex M. PMID: 26028155; PMCID: PMC4450241.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    34. Distal leg epidermal nerve fiber density as a surrogate marker of HIV-associated sensory neuropathy risk: risk factors and change following initial antiretroviral therapy. J Neurovirol. 2015 Oct; 21(5):525-34. Shikuma CM, Bennett K, Ananworanich J, Gerschenson M, Teeratakulpisarn N, Jadwattanakul T, DeGruttola V, McArthur JC, Ebenezer G, Chomchey N, Praihirunkit P, Hongchookiat P, Mathajittiphun P, Nakamoto B, Hauer P, Phanuphak P, Phanuphak N, SEARCH 003 protocol team. PMID: 26002840; PMCID: PMC4611029.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    35. Importance of Viral Sequence Length and Number of Variable and Informative Sites in Analysis of HIV Clustering. AIDS Res Hum Retroviruses. 2015 May; 31(5):531-42. Novitsky V, Moyo S, Lei Q, DeGruttola V, Essex M. PMID: 25560745; PMCID: PMC4426322.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    36. Predicting time to threshold for initiating antiretroviral treatment to evaluate cost of treatment as prevention of human immunodeficiency virus. J R Stat Soc Ser C Appl Stat. 2015 02 01; 64(2):359-375. Lynch ML, DeGruttola V. PMID: 25620814; PMCID: PMC4302962.
      View in: PubMed   Mentions: 2  
    37. Impact of sampling density on the extent of HIV clustering. AIDS Res Hum Retroviruses. 2014 Dec; 30(12):1226-35. Novitsky V, Moyo S, Lei Q, DeGruttola V, Essex M. PMID: 25275430; PMCID: PMC4250956.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    38. Toward an endgame: finding and engaging people unaware of their HIV-1 infection in treatment and prevention. AIDS Res Hum Retroviruses. 2014 Mar; 30(3):217-24. Burns DN, DeGruttola V, Pilcher CD, Kretzschmar M, Gordon CM, Flanagan EH, Duncombe C, Cohen MS. PMID: 24410300; PMCID: PMC3938938.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansPHPublic Health
    39. Phylogenetic relatedness of circulating HIV-1C variants in Mochudi, Botswana. PLoS One. 2013; 8(12):e80589. Novitsky V, Bussmann H, Logan A, Moyo S, van Widenfelt E, Okui L, Mmalane M, Baca J, Buck L, Phillips E, Tim D, McLane MF, Lei Q, Wang R, Makhema J, Lockman S, DeGruttola V, Essex M. PMID: 24349005; PMCID: PMC3859477.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    40. University of Pennsylvania 5th annual conference on statistical issues in clinical trials: emerging statistical issues in biomarker validation (afternoon session). Clin Trials. 2013 Oct; 10(5):701-8. Rubin E, LaVange L, DeGruttola V. PMID: 23988466.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    41. HIV DNA reservoir increases risk for cognitive disorders in cART-naïve patients. PLoS One. 2013; 8(7):e70164. Valcour VG, Ananworanich J, Agsalda M, Sailasuta N, Chalermchai T, Schuetz A, Shikuma C, Liang CY, Jirajariyavej S, Sithinamsuwan P, Tipsuk S, Clifford DB, Paul R, Fletcher JL, Marovich MA, Slike BM, DeGruttola V, Shiramizu B, SEARCH 011 Protocol Team. PMID: 23936155; PMCID: PMC3729685.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    42. Bayesian estimation of mixture models with prespecified elements to compare drug resistance in treatment-naïve and experienced tuberculosis cases. PLoS Comput Biol. 2013; 9(3):e1002973. Izu A, Cohen T, Degruttola V. PMID: 23555210; PMCID: PMC3605089.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    43. Trail Making Test A improves performance characteristics of the International HIV Dementia Scale to identify symptomatic HAND. J Neurovirol. 2013 Apr; 19(2):137-43. Chalermchai T, Valcour V, Sithinamsuwan P, Pinyakorn S, Clifford D, Paul RH, Tipsuk S, Fletcher JL, Degruttola V, Ratto-Kim S, Hutchings N, Shikuma C, Ananworanich J, SEARCH 007 and 011 study groups. PMID: 23483520; PMCID: PMC3644005.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    44. Change in brain magnetic resonance spectroscopy after treatment during acute HIV infection. PLoS One. 2012; 7(11):e49272. Sailasuta N, Ross W, Ananworanich J, Chalermchai T, DeGruttola V, Lerdlum S, Pothisri M, Busovaca E, Ratto-Kim S, Jagodzinski L, Spudich S, Michael N, Kim JH, Valcour V, RV254/SEARCH 010 protocol teams. PMID: 23229129; PMCID: PMC3500278.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCellsCTClinical Trials
    45. Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV. Antivir Ther. 2012; 17(7):1233-42. Shikuma CM, Nakamoto B, Shiramizu B, Liang CY, DeGruttola V, Bennett K, Paul R, Kallianpur K, Chow D, Gavegnano C, Hurwitz SJ, Schinazi RF, Valcour VG. PMID: 23018140; PMCID: PMC3715550.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    46. Recursive partitioning for monotone missing at random longitudinal markers. Stat Med. 2013 Mar 15; 32(6):978-94. Stock S, DeGruttola V. PMID: 22941582; PMCID: PMC3754451.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    47. Resampling-based methods in single and multiple testing for equality of covariance/correlation matrices. Int J Biostat. 2012 Jun 22; 8(1):Article 13. Yang Y, DeGruttola V. PMID: 22740584; PMCID: PMC5027617.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    48. Risk factors for symptomatic hyperlactatemia and lactic acidosis among combination antiretroviral therapy-treated adults in Botswana: results from a clinical trial. AIDS Res Hum Retroviruses. 2012 Aug; 28(8):759-65. Wester CW, Eden SK, Shepherd BE, Bussmann H, Novitsky V, Samuels DC, Hendrickson SL, Winkler CA, O'Brien SJ, Essex M, D'Aquila RT, DeGruttola V, Marlink RG. PMID: 22540188; PMCID: PMC3399551.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    49. Determinants of epidermal nerve fibre density in antiretroviral-naïve HIV-infected individuals. HIV Med. 2012 Nov; 13(10):602-8. Shikuma C, Gerschenson M, Ananworanich J, Valcour V, Teeratakulpisarn N, Jadwattanakul T, Degruttola V, Liang CY, McArthur J, Ebenezer G, Chomchey N, Praihirunkit P, Hongchookiath P, Mathajittiphun P, Nakamoto B, Hauer P, Phanuphak P, Phanuphak N, SEARCH 003 protocol team. PMID: 22574621; PMCID: PMC3654839.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    50. Editorial commentary: network epidemic models: assumptions and interpretations. Clin Infect Dis. 2012 Jul; 55(2):276-8. Goyal R, Wang R, DeGruttola V. PMID: 22491502; PMCID: PMC3403840.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    51. Effect modification by sex and baseline CD4+ cell count among adults receiving combination antiretroviral therapy in Botswana: results from a clinical trial. AIDS Res Hum Retroviruses. 2012 Sep; 28(9):981-8. Wester CW, Stitelman OM, deGruttola V, Bussmann H, Marlink RG, van der Laan MJ. PMID: 22309114; PMCID: PMC3423643.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    52. Impact of time to start treatment following infection with application to initiating HAART in HIV-positive patients. Biometrics. 2012 Sep; 68(3):745-54. Lok JJ, DeGruttola V. PMID: 22352840; PMCID: PMC3811162.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    53. The setpoint study (ACTG A5217): effect of immediate versus deferred antiretroviral therapy on virologic set point in recently HIV-1-infected individuals. J Infect Dis. 2012 Jan 01; 205(1):87-96. Hogan CM, Degruttola V, Sun X, Fiscus SA, Del Rio C, Hare CB, Markowitz M, Connick E, Macatangay B, Tashima KT, Kallungal B, Camp R, Morton T, Daar ES, Little S, A5217 Study Team. PMID: 22180621; PMCID: PMC3242744.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    54. Vitamin D levels and markers of arterial dysfunction in HIV. AIDS Res Hum Retroviruses. 2012 Aug; 28(8):793-7. Shikuma CM, Seto T, Liang CY, Bennett K, DeGruttola V, Gerschenson M, Stein JH, Budoff M, Hodis HN, Delaney JA, Ogata-Arakaki D, Pramyothin P, Chow D. PMID: 21978287; PMCID: PMC3399561.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    55. Can computer-based feedback improve emergency department patient uptake of rapid HIV screening? Ann Emerg Med. 2011 Jul; 58(1 Suppl 1):S114-9.e1-2. Merchant RC, Clark MA, Langan TJ, Mayer KH, Seage GR, DeGruttola VG. PMID: 21684389; PMCID: PMC3205940.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansPHPublic Health
    56. Recursive partitioning of resistant mutations for longitudinal markers based on a U-type score. Biostatistics. 2011 Oct; 12(4):750-62. Hu C, Degruttola V. PMID: 21596729; PMCID: PMC3169671.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    57. Antiretroviral therapy as prevention: linking the mainframe to Main Street. Clin Infect Dis. 2011 Apr 15; 52(8):1050-2. DeGruttola V, Schooley RT. PMID: 21460323; PMCID: PMC3070032.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    58. Statistical interpretation of the RV144 HIV vaccine efficacy trial in Thailand: a case study for statistical issues in efficacy trials. J Infect Dis. 2011 Apr 01; 203(7):969-75. Gilbert PB, Berger JO, Stablein D, Becker S, Essex M, Hammer SM, Kim JH, Degruttola VG. PMID: 21402548; PMCID: PMC3068028.
      View in: PubMed   Mentions: 55     Fields:    Translation:Humans
    59. Strengthening biostatistics resources in sub-Saharan Africa: research collaborations through U.S. partnerships. Stat Med. 2011 Mar 30; 30(7):695-708. Gezmu M, DeGruttola V, Dixon D, Essex M, Halloran E, Hogan J, Grobler A, Kim S, McDermott J, McKaig R, Neaton JD. PMID: 21394746; PMCID: PMC4562470.
      View in: PubMed   Mentions: 17     Fields:    Translation:PHPublic Health
    60. Implications of HIV PrEP trials results. AIDS Res Hum Retroviruses. 2011 Jan; 27(1):81-90. Veronese F, Anton P, Fletcher CV, DeGruttola V, McGowan I, Becker S, Zwerski S, Burns D, Workshop Organizing Committee. PMID: 20969483; PMCID: PMC3014767.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    61. HIV-1 diversity after a class switch failure. AIDS Res Hum Retroviruses. 2010 Nov; 26(11):1175-80. Kolber MA, Buendia P, Degruttola V, Moore RD. PMID: 20854203; PMCID: PMC3000642.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    62. Developing and evaluating comprehensive HIV infection control strategies: issues and challenges. Clin Infect Dis. 2010 May 15; 50 Suppl 3:S102-7. DeGruttola V, Smith DM, Little SJ, Miller V. PMID: 20397937; PMCID: PMC2913596.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansPHPublic Health
    63. HIV-1 subtype C-infected individuals maintaining high viral load as potential targets for the "test-and-treat" approach to reduce HIV transmission. PLoS One. 2010 Apr 12; 5(4):e10148. Novitsky V, Wang R, Bussmann H, Lockman S, Baum M, Shapiro R, Thior I, Wester C, Wester CW, Ogwu A, Asmelash A, Musonda R, Campa A, Moyo S, van Widenfelt E, Mine M, Moffat C, Mmalane M, Makhema J, Marlink R, Gilbert P, Seage GR, DeGruttola V, Essex M. PMID: 20405044; PMCID: PMC2853582.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCellsPHPublic Health
    64. Development of a didanosine genotypic resistance interpretation system based on large derivation and validation datasets. AIDS. 2010 Jan 28; 24(3):365-71. Assoumou L, Cozzi-Lepri A, Brun-Vézinet F, Degruttola V, Kuritzkes DR, Phillips A, Zolopa A, Miller V, Flandre P, Costagliola D, Standardization, Clinical Relevance of HIV Drug Resistance Testing Project from the Forum for Collab. PMID: 19864933.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    65. Adherence to antiretroviral therapy, virological response, and time to resistance in the Dakar cohort. Stat Med. 2010 Jan 15; 29(1):14-32. Tournoud M, Etard JF, Ecochard R, DeGruttola V. PMID: 19941299; PMCID: PMC3388622.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    66. The relationship of reported HIV risk and history of HIV testing among emergency department patients. Postgrad Med. 2010 Jan; 122(1):61-74. Merchant RC, Freelove SM, Langan TJ, Clark MA, Mayer KH, Seage GR, DeGruttola VG. PMID: 20107290; PMCID: PMC3172990.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    67. Non-nucleoside reverse transcriptase inhibitor outcomes among combination antiretroviral therapy-treated adults in Botswana. AIDS. 2010 Jan; 24 Suppl 1:S27-36. Wester CW, Thomas AM, Bussmann H, Moyo S, Makhema JM, Gaolathe T, Novitsky V, Essex M, deGruttola V, Marlink RG. PMID: 20023437; PMCID: PMC3087813.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    68. Effectiveness of increasing emergency department patients' self-perceived risk for being human immunodeficiency virus (HIV) infected through audio computer self-interview-based feedback about reported HIV risk behaviors. Acad Emerg Med. 2009 Nov; 16(11):1143-55. Merchant RC, Clark MA, Langan TJ, Seage GR, Mayer KH, DeGruttola VG. PMID: 20053235; PMCID: PMC3173950.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic Health
    69. A phylogenetic and Markov model approach for the reconstruction of mutational pathways of drug resistance. Bioinformatics. 2009 Oct 01; 25(19):2522-9. Buendia P, Cadwallader B, DeGruttola V. PMID: 19654117; PMCID: PMC2752619.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    70. Response to zidovudine/didanosine-containing combination antiretroviral therapy among HIV-1 subtype C-infected adults in Botswana: two-year outcomes from a randomized clinical trial. J Acquir Immune Defic Syndr. 2009 May 01; 51(1):37-46. Bussmann H, Wester CW, Thomas A, Novitsky V, Okezie R, Muzenda T, Gaolathe T, Ndwapi N, Mawoko N, Widenfelt E, Moyo S, Musonda R, Mine M, Makhema J, Moffat H, Essex M, Degruttola V, Marlink RG. PMID: 19282782; PMCID: PMC3066172.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    71. Emergency department patient perceptions and preferences on opt-in rapid HIV screening program components. AIDS Care. 2009 Apr; 21(4):490-500. Merchant RC, Clark MA, Seage GR, Mayer KH, Degruttola VG, Becker BM. PMID: 19283644; PMCID: PMC3173939.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansPHPublic Health
    72. HIV DNA and cognition in a Thai longitudinal HAART initiation cohort: the SEARCH 001 Cohort Study. Neurology. 2009 Mar 17; 72(11):992-8. Valcour VG, Shiramizu BT, Sithinamsuwan P, Nidhinandana S, Ratto-Kim S, Ananworanich J, Siangphoe U, Kim JH, de Souza M, Degruttola V, Paul RH, Shikuma CM, Southeast Asia Research Collaboration with the University of Hawaii 001 protocol team. PMID: 19289739; PMCID: PMC2677463.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    73. Demographic variations in HIV testing history among emergency department patients: implications for HIV screening in US emergency departments. J Med Screen. 2009; 16(2):60-6. Merchant RC, Catanzaro BM, Seage GR, Mayer KH, Clark MA, Degruttola VG, Becker BM. PMID: 19564517; PMCID: PMC3174686.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic Health
    74. Video as an effective method to deliver pretest information for rapid human immunodeficiency testing. Acad Emerg Med. 2009 Feb; 16(2):124-35. Merchant RC, Clark MA, Mayer KH, Seage Iii GR, DeGruttola VG, Becker BM. PMID: 19120050; PMCID: PMC2633421.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansPHPublic Health
    75. Controlling the HIV epidemic, without a vaccine! AIDS. 2008 Nov 30; 22(18):2554-5. DeGruttola V, Little S, Schooley R. PMID: 19005285; PMCID: PMC6037487.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    76. Five-year outcomes of initial patients treated in Botswana's National Antiretroviral Treatment Program. AIDS. 2008 Nov 12; 22(17):2303-11. Bussmann H, Wester CW, Ndwapi N, Grundmann N, Gaolathe T, Puvimanasinghe J, Avalos A, Mine M, Seipone K, Essex M, Degruttola V, Marlink RG. PMID: 18981769; PMCID: PMC2853026.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    77. Emergency department patient acceptance of opt-in, universal, rapid HIV screening. Public Health Rep. 2008 Nov-Dec; 123 Suppl 3:27-40. Merchant RC, Seage GR, Mayer KH, Clark MA, DeGruttola VG, Becker BM. PMID: 19172704; PMCID: PMC2567017.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansPHPublic Health
    78. Resampling-based analyses of the effects of combinations of HIV genetic mutations on drug susceptibility. Stat Med. 2008 Oct 15; 27(23):4740-57. Schumi J, Degruttola V. PMID: 18186529.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    79. Testing for associations with missing high-dimensional categorical covariates. Int J Biostat. 2008 Sep 29; 4(1):Article 18. Schumi J, DiRienzo AG, DeGruttola V. PMID: 20231909; PMCID: PMC2835453.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    80. Initiatives for developing and comparing genotype interpretation systems: external validation of existing systems for didanosine against virological response. J Infect Dis. 2008 Aug 15; 198(4):470-80. Assoumou L, Brun-Vézinet F, Cozzi-Lepri A, Kuritzkes D, Phillips A, Zolopa A, Degruttola V, Miller V, Costagliola D, Standardization and Clinical Relevance of HIV Drug Resistance Testing Project of the Forum for Colla. PMID: 18598191.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    81. Accommodating uncertainty in a tree set for function estimation. Stat Appl Genet Mol Biol. 2008; 7(1):Article5. Healy BC, DeGruttola VG, Hu C. PMID: 18312210.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    82. Two-sample tests of area-under-the-curve in the presence of missing data. Int J Biostat. 2008 Jan 17; 4(1):Article 1. Spritzler J, DeGruttola VG, Pei L. PMID: 20231907; PMCID: PMC2835452.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    83. Association of efavirenz hypersusceptibility with virologic response in ACTG 368, a randomized trial of abacavir (ABC) in combination with efavirenz (EFV) and indinavir (IDV) in HIV-infected subjects with prior nucleoside analog experience. HIV Clin Trials. 2008 Jan-Feb; 9(1):11-25. Demeter LM, DeGruttola V, Lustgarten S, Bettendorf D, Fischl M, Eshleman S, Spreen W, Nguyen BY, Koval CE, Eron JJ, Hammer S, Squires K. PMID: 18215978; PMCID: PMC2821073.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    84. Higher-than-expected rates of lactic acidosis among highly active antiretroviral therapy-treated women in Botswana: preliminary results from a large randomized clinical trial. J Acquir Immune Defic Syndr. 2007 Nov 01; 46(3):318-22. Wester CW, Okezie OA, Thomas AM, Bussmann H, Moyo S, Muzenda T, Makhema J, van Widenfelt E, Musonda R, Novitsky V, Gaolathe T, Ndwapi N, Essex M, Kuritzkes DR, DeGruttola V, Marlink RG. PMID: 18090299.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    85. Resampling-based multiple testing methods with covariate adjustment: application to investigation of antiretroviral drug susceptibility. Biometrics. 2008 Jun; 64(2):329-36. Yang Y, Degruttola V. PMID: 17900313.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    86. Comparison of patient comprehension of rapid HIV pre-test fundamentals by information delivery format in an emergency department setting. BMC Public Health. 2007 Sep 12; 7:238. Merchant RC, Gee EM, Clark MA, Mayer KH, Seage GR, Degruttola VG. PMID: 17850670; PMCID: PMC2080636.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    87. Efficient Hybrid EM for Linear and Nonlinear Mixed Effects Models with Censored Response. Comput Stat Data Anal. 2007 Aug 15; 51(12):5718-5730. Vaida F, Fitzgerald AP, Degruttola V. PMID: 19578533; PMCID: PMC2705201.
      View in: PubMed   Mentions: 21  
    88. The reverse transcriptase 67N 70R 215Y genotype is the predominant TAM pathway associated with virologic failure among HIV type 1C-infected adults treated with ZDV/ddI-containing HAART in southern Africa. AIDS Res Hum Retroviruses. 2007 Jul; 23(7):868-78. Novitsky V, Wester CW, DeGruttola V, Bussmann H, Gaseitsiwe S, Thomas A, Moyo S, Musonda R, Van Widenfelt E, Marlink RG, Essex M. PMID: 17678469.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    89. Nonparametric tests for two-group comparisons of dependent observations obtained at varying time points. Biometrics. 2007 Mar; 63(1):194-200. May S, Degruttola V. PMID: 17447945.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    90. A resampling-based approach to multiple testing with uncertainty in phase. Int J Biostat. 2007; 3(1):Article 2. Foulkes AS, DeGruttola VG. PMID: 22550644.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    91. Host immune status and incidence of hepatocellular carcinoma among subjects infected with hepatitis C virus: a nested case-control study in Japan. Cancer Epidemiol Biomarkers Prev. 2006 Dec; 15(12):2521-5. Suruki RY, Mueller N, Hayashi K, Harn D, DeGruttola V, Raker CA, Tsubouchi H, Stuver SO. PMID: 17164379.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    92. Hidden Markov models for settings with interval-censored transition times and uncertain time origin: application to HIV genetic analyses. Biostatistics. 2007 Apr; 8(2):438-52. Healy B, Degruttola V. PMID: 16940036.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    93. Longitudinal analysis of clinical markers following antiretroviral therapy initiated during acute or early HIV type 1 infection. Clin Infect Dis. 2006 Apr 01; 42(7):1024-31. Kassutto S, Maghsoudi K, Johnston MN, Robbins GK, Burgett NC, Sax PE, Cohen D, Pae E, Davis B, Zachary K, Basgoz N, D'agata EM, DeGruttola V, Walker BD, Rosenberg ES. PMID: 16511771.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    94. A flexible B-spline model for multiple longitudinal biomarkers and survival. Biometrics. 2005 Mar; 61(1):64-73. Brown ER, Ibrahim JG, DeGruttola V. PMID: 15737079.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    95. Clinically validated genotype analysis: guiding principles and statistical concerns. Antivir Ther. 2004 Aug; 9(4):465-78. Brun-Vézinet F, Costagliola D, Khaled MA, Calvez V, Clavel F, Clotet B, Haubrich R, Kempf D, King M, Kuritzkes D, Lanier R, Miller M, Miller V, Phillips A, Pillay D, Schapiro J, Scott J, Shafer R, Zazzi M, Zolopa A, DeGruttola V. PMID: 15456077.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    96. Immunophenotypic markers and antiretroviral therapy (IMART): T cell activation and maturation help predict treatment response. J Infect Dis. 2004 May 15; 189(10):1811-20. Mildvan D, Bosch RJ, Kim RS, Spritzler J, Haas DW, Kuritzkes D, Kagan J, Nokta M, DeGruttola V, Moreno M, Landay A. PMID: 15122517.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCellsCTClinical Trials
    97. A randomized trial of nelfinavir and abacavir in combination with efavirenz and adefovir dipivoxil in HIV-1-infected persons with virological failure receiving indinavir. Antivir Ther. 2003 Dec; 8(6):507-18. Hammer SM, Bassett R, Squires KE, Fischl MA, Demeter LM, Currier JS, Mellors JW, Morse GD, Eron JJ, Santana JL, DeGruttola V, ACTG 372B/D Study Team. PMID: 14760884.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsCTClinical Trials
    98. Assessing resistance costs of antiretroviral therapies via measures of future drug options. J Infect Dis. 2003 Oct 01; 188(7):1001-8. Jiang H, Deeks SG, Kuritzkes DR, Lallemant M, Katzenstein D, Albrecht M, DeGruttola V. PMID: 14513420.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    99. Non-parametric methods to predict HIV drug susceptibility phenotype from genotype. Stat Med. 2003 Sep 15; 22(17):2785-98. DiRienzo AG, DeGruttola V, Larder B, Hertogs K. PMID: 12939786.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    100. Characterizing classes of antiretroviral drugs by genotype. Stat Med. 2003 Aug 30; 22(16):2637-55. Foulkes AS, DeGruttola V. PMID: 12898549.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    101. What constitutes efficacy for a human immunodeficiency virus vaccine that ameliorates viremia: issues involving surrogate end points in phase 3 trials. J Infect Dis. 2003 Jul 15; 188(2):179-93. Gilbert PB, DeGruttola VG, Hudgens MG, Self SG, Hammer SM, Corey L. PMID: 12854072.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    102. Design and analysis of clinical trials with a bivariate failure time endpoint, with application to AIDS Clinical Trials Group Study A5142. Control Clin Trials. 2003 Apr; 24(2):122-34. DiRienzo AG, DeGruttola V. PMID: 12689734.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    103. Baseline predictors of CD4 T-lymphocyte recovery with combination antiretroviral therapy. J Acquir Immune Defic Syndr. 2002 Sep 01; 31(1):20-6. Bennett KK, DeGruttola VG, Marschner IC, Havlir DV, Richman DD. PMID: 12352146.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    104. Modelling HIV viral rebound using non-linear mixed effects models. Stat Med. 2002 Jul 30; 21(14):2093-108. Fitzgerald AP, DeGruttola VG, Vaida F. PMID: 12111889.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    105. Dual vs single protease inhibitor therapy following antiretroviral treatment failure: a randomized trial. JAMA. 2002 Jul 10; 288(2):169-80. Hammer SM, Vaida F, Bennett KK, Holohan MK, Sheiner L, Eron JJ, Wheat LJ, Mitsuyasu RT, Gulick RM, Valentine FT, Aberg JA, Rogers MD, Karol CN, Saah AJ, Lewis RH, Bessen LJ, Brosgart C, DeGruttola V, Mellors JW, AIDS Clinical Trials Group 398 Study Team. PMID: 12095381.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCTClinical Trials
    106. ACTG (AIDS Clinical Trials Group) 384: a strategy trial comparing consecutive treatments for HIV-1. Control Clin Trials. 2001 Apr; 22(2):142-59. Smeaton LM, DeGruttola V, Robbins GK, Shafer RW. PMID: 11306153; PMCID: PMC4767253.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    107. Virologic and regimen termination surrogate end points in AIDS clinical trials. JAMA. 2001 Feb 14; 285(6):777-84. Gilbert PB, DeGruttola V, Hammer SM, Kuritzkes DR. PMID: 11176916.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    108. Two double-blinded, randomized, comparative trials of 4 human immunodeficiency virus type 1 (HIV-1) envelope vaccines in HIV-1-infected individuals across a spectrum of disease severity: AIDS Clinical Trials Groups 209 and 214. J Infect Dis. 2000 Nov; 182(5):1357-64. Schooley RT, Spino C, Kuritzkes D, Walker BD, Valentine FA, Hirsch MS, Cooney E, Friedland G, Kundu S, Merigan TC, McElrath MJ, Collier A, Plaeger S, Mitsuyasu R, Kahn J, Haslett P, Uherova P, deGruttola V, Chiu S, Zhang B, Jones G, Bell D, Ketter N, Twadell T, Chernoff D, Rosandich M. PMID: 11023459.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    109. Methods for investigation of the relationship between drug-susceptibility phenotype and human immunodeficiency virus type 1 genotype with applications to AIDS clinical trials group 333. J Infect Dis. 2000 Jul; 182(1):59-67. Sevin AD, DeGruttola V, Nijhuis M, Schapiro JM, Foulkes AS, Para MF, Boucher CA. PMID: 10882582.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCellsCTClinical Trials
    110. Both serum HIV type 1 RNA levels and CD4+ lymphocyte counts predict clinical outcome in HIV type 1-infected subjects with 200 to 500 CD4+ cells per cubic millimeter. AIDS Clinical Trials Group Study 175 Virology Study Team. AIDS Res Hum Retroviruses. 2000 May 01; 16(7):645-53. Kim S, Hughes MD, Hammer SM, Jackson JB, DeGruttola V, Katzenstein DA. PMID: 10791875.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsCTClinical Trials
    111. Beta-blockade for patients undergoing vascular surgery. N Engl J Med. 2000 Apr 06; 342(14):1052; author reply 1052-3. Litwack RS, Gilligan DM, DeGruttola V. PMID: 10755897.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    112. The relation between baseline HIV drug resistance and response to antiretroviral therapy: re-analysis of retrospective and prospective studies using a standardized data analysis plan. Antivir Ther. 2000 Mar; 5(1):41-8. DeGruttola V, Dix L, D'Aquila R, Holder D, Phillips A, Ait-Khaled M, Baxter J, Clevenbergh P, Hammer S, Harrigan R, Katzenstein D, Lanier R, Miller M, Para M, Yerly S, Zolopa A, Murray J, Patick A, Miller V, Castillo S, Pedneault L, Mellors J. PMID: 10846592.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    113. Treatment with amprenavir alone or amprenavir with zidovudine and lamivudine in adults with human immunodeficiency virus infection. AIDS Clinical Trials Group 347 Study Team. J Infect Dis. 1999 Apr; 179(4):808-16. Murphy RL, Gulick RM, DeGruttola V, D'Aquila RT, Eron JJ, Sommadossi JP, Currier JS, Smeaton L, Frank I, Caliendo AM, Gerber JG, Tung R, Kuritzkes DR. PMID: 10068575.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
    114. Clinical trials using HIV-1 RNA-based primary endpoints: statistical analysis and potential biases. J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Mar 01; 20(3):220-7. Marschner IC, Betensky RA, DeGruttola V, Hammer SM, Kuritzkes DR. PMID: 10077169.
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    115. Predicting long-term postoperative cardiovascular outcomes. Anesthesiology. 1998 Nov; 89(5):1286-8. Litwack RS, DeGruttola V. PMID: 9822031.
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    116. Efficient trial designs for studying combination antiretroviral treatments in patients with various resistance profiles. J Infect Dis. 1998 Aug; 178(2):340-8. Gilbert P, DeGruttola V, Hammer S. PMID: 9697713.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    117. Use of changes in plasma levels of human immunodeficiency virus type 1 RNA to assess the clinical benefit of antiretroviral therapy. J Infect Dis. 1998 Jan; 177(1):40-7. Marschner IC, Collier AC, Coombs RW, D'Aquila RT, DeGruttola V, Fischl MA, Hammer SM, Hughes MD, Johnson VA, Katzenstein DA, Richman DD, Smeaton LM, Spector SA, Saag MS. PMID: 9419168.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCellsCTClinical Trials
    118. Trial design in the era of highly effective antiviral drug combinations for HIV infection. AIDS. 1998; 12 Suppl A:S149-56. DeGruttola V, Hughes M, Gilbert P, Phillips A. PMID: 9632997.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    119. Surrogate endpoints. AIDS Clin Rev. 1997-1998; 129-43. Fleming TR, DeGruttola V, DeMets DL. PMID: 9305447.
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    120. Models for empirical Bayes estimators of longitudinal CD4 counts. Stat Med. 1996 Nov 15-30; 15(21-22):2289-305; discussion 2337-40. LaValley MP, DeGruttola V. PMID: 8931202.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    121. Lack of effect of cimetidine on lymphocyte subsets in patients infected with human immunodeficiency virus type 1. Clin Infect Dis. 1996 Nov; 23(5):1049-54. Cohen CJ, Hellinger JA, Day J, Salitsky N, Shevitz A, Zackin R, DeGruttola V. PMID: 8922801.
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    122. Association of plasma human immunodeficiency virus type 1 RNA level with risk of clinical progression in patients with advanced infection. AIDS Clinical Trials Group (ACTG) 116B/117 Study Team. ACTG Virology Committee Resistance and HIV-1 RNA Working Groups. J Infect Dis. 1996 Oct; 174(4):704-12. Coombs RW, Welles SL, Hooper C, Reichelderfer PS, D'Aquila RT, Japour AJ, Johnson VA, Kuritzkes DR, Richman DD, Kwok S, Todd J, Jackson JB, DeGruttola V, Crumpacker CS, Kahn J. PMID: 8843206.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    123. Randomized study of didanosine monotherapy and combination therapy with zidovudine in hemophilic and nonhemophilic subjects with asymptomatic human immunodeficiency virus-1 infection. AIDS Clinical Trial Groups. Blood. 1995 May 01; 85(9):2337-46. Ragni MV, Amato DA, LoFaro ML, DeGruttola V, Van Der Horst C, Eyster ME, Kessler CM, Gjerset GF, Ho M, Parenti DM, et al. PMID: 7727768.
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    124. Zidovudine resistance and HIV-1 disease progression during antiretroviral therapy. AIDS Clinical Trials Group Protocol 116B/117 Team and the Virology Committee Resistance Working Group. Ann Intern Med. 1995 Mar 15; 122(6):401-8. D'Aquila RT, Johnson VA, Welles SL, Japour AJ, Kuritzkes DR, DeGruttola V, Reichelderfer PS, Coombs RW, Crumpacker CS, Kahn JO, Richman DD. PMID: 7856987.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCellsCTClinical Trials
    125. Human immunodeficiency virus type 1 quantitative cell microculture as a measure of antiviral efficacy in a multicenter clinical trial. J Infect Dis. 1995 Feb; 171(2):305-11. Fiscus SA, DeGruttola V, Gupta P, Katzenstein DA, Meyer WA, LoFaro ML, Katzman M, Ragni MV, Reichelderfer PS, Coombs RW. PMID: 7844365.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    126. Evaluating surrogate markers. J Acquir Immune Defic Syndr Hum Retrovirol. 1995; 10 Suppl 2:S1-8. Hughes MD, DeGruttola V, Welles SL. PMID: 7552506.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    127. The effect of covariates on the induction time of AIDS using improved imputation of exact seroconversion times. Stat Med. 1994 Oct 15-30; 13(19-20):2021-30. Gauvreau K, Degruttola V, Pagano M, Bellocco R. PMID: 7846407.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    128. Serum p24 antigen level as an intermediate end point in clinical trials of zidovudine in people infected with human immunodeficiency virus type 1. Aids Clinical Trials Group Virology Laboratories. J Infect Dis. 1994 Apr; 169(4):713-21. DeGruttola V, Beckett LA, Coombs RW, Arduino JM, Balfour HH, Rasheed S, Hollinger FB, Fischl MA, Volberding P. PMID: 8133085.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsCTClinical Trials
    129. Infectiousness of HIV between male homosexual partners. J Clin Epidemiol. 1989; 42(9):849-56. DeGruttola V, Seage GR, Mayer KH, Horsburgh CR. PMID: 2789269.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    130. Human immunodeficiency virus and oral intercourse. Ann Intern Med. 1987 Sep; 107(3):428-9. DeGruttola V, Mayer KH. PMID: 3619236.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    131. Regional and urban-suburban differentials in coronary heart disease mortality and risk factor prevalence. J Chronic Dis. 1981; 34(1):11-9. Kleinman JC, DeGruttola VG, Cohen BB, Madans JH. PMID: 7451636.
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