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Age-related dry eye disease: Redefining a distinct subtype driven by aging. Ocul Surf. 2026 Jul; 41:171-184.
Zhang Z, Yuan Y, He Y, Chi K, Zeng H, Deng Y, Wang B, Yu H, Calder VL, Yuan J, Zuo X. PMID: 42276417.
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Humans
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FGD3 as a prognostic and immunological biomarker: a pan-cancer analysis of its role in tumor progression and the immune landscape. Cancer Cell Int. 2026 Jun 10.
Zhu J, Yu C, Xu X, Zuo X, Li J, Wang R, Li X, Sun A, Wang S, Jiang C. PMID: 42271337.
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Preformed fibrils of α-synuclein rapidly activate LRRK2 on early endosomes, driving Rab5 phosphorylation and disrupting endolysosomal and synaptic function. NPJ Parkinsons Dis. 2026 May 12.
Zuo X, Chen Z, Chen XQ, Guan D, Shaw PX, Johnstone A, Becker A, Das U, Mobley WC. PMID: 42120407.
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Linking accelerated biological ageing to cataract susceptibility: evidence from cross-cohort analysis. Br J Ophthalmol. 2026 May 12.
Chi K, He Y, Zuo X, Lai C, Cao J, Ying Y, Zhang B, Li R, Chen M, Tan X, Li Q, Wang S, Wu Q, He J, Liu L, Hu Y, Zhu Z, Zhang X, Yu H. PMID: 42097863.
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PubMed Mentions: Fields:
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Reversing the Conductance Evolution of Azobenzene Derivatives in Photoisomerization. Phys Rev Lett. 2025 Nov 21; 135(21):218001.
Zhang D, Feng Y, Xu X, Jia K, Emusani R, Zhang ZY, Zhang J, Zuo X, Zhao Z, Li T, Ma L, Xiang D. PMID: 41349079.
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Tau pathology differs by sex in Alzheimer's disease in Down syndrome. Alzheimers Dement. 2025 10; 21(10):e70838.
Chen XQ, Zuo X, Mobley WC. PMID: 41126730; PMCID: PMC12547191.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Regulating enol-keto tautomerism at the single-molecule level with a confined optical field. Chem Sci. 2025 Oct 01; 16(38):17850-17858.
Adijiang A, Ge Y, Feng H, Yan Y, Zuo X, Wang H, Zhao X, Tan M, Zhang S, Xu X, Chen L, Wang C, Li Z, Xiang D. PMID: 40918718; PMCID: PMC12412053.
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Melatonin Ameliorates Circadian Disruption-Associated Dry Eye via Modulation of BMAL1-REV-ERBα-IL-17 Axis and Ocular Surface Microbiota Homeostasis. J Pineal Res. 2025 Sep; 77(5):e70076.
Wang B, Zeng H, Yang X, Zuo X, Liang L, Zhang R, Deng W, Ju R, Wang X, Yuan J. PMID: 40936475.
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Translation:
Animals
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Hyperactivation of RAB5 disrupts the endosomal Rab cascade leading to endolysosomal dysregulation in Down syndrome: A necessary role for increased APP gene dose. Alzheimers Dement. 2025 05; 21(5):e70046.
Chen XQ, Zuo X, Becker A, Mobley WC. PMID: 40339170; PMCID: PMC12058456.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Antisense oligonucleotides directed against App and Rab5 normalized endosomal Rab activity and reversed DS-AD-linked degenerative phenotypes in the Dp16 mouse model of Down syndrome. Alzheimers Dement. 2025 05; 21(5):e70022.
Chen XQ, Zuo X, Becker A, Mante M, Florio JB, Jadhav SG, Albay R, Johnstone A, Karachentsev D, Rissman R, Zhao H, Dowdy SF, Mobley WC. PMID: 40339155; PMCID: PMC12058459.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Mitochondrial Imbalance in Down Syndrome: A Driver of Accelerated Brain Aging? Aging Dis. 2025 Apr 06; 16(5):2674-2694.
Zuo X. PMID: 40249934; PMCID: PMC12339184.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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From gene to therapy: a review of deciphering the role of ABCD1 in combating X-Linked adrenoleukodystrophy. Lipids Health Dis. 2024 Nov 11; 23(1):369.
Zuo X, Chen Z. PMID: 39529100; PMCID: PMC11552335.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Rice's trajectory from wild to domesticated in East Asia. Science. 2024 05 24; 384(6698):901-906.
Zhang J, Jiang L, Yu L, Huan X, Zhou L, Wang C, Jin J, Zuo X, Wu N, Zhao Z, Sun H, Yu Z, Zhang G, Zhu J, Wu Z, Dong Y, Fan B, Shen C, Lu H. PMID: 38781358.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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New insights into the effects of APP gene dose on synapse in Down syndrome. Neural Regen Res. 2024 May; 19(5):961-962.
Chen XQ, Zuo X. PMID: 37862189; PMCID: PMC10749626.
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In-house ammonia induced lung impairment and oxidative stress of ducks. Poult Sci. 2024 May; 103(5):103622.
Liu B, Yang Y, Fu Y, Zhao Y, Chen W, Wei S, Zuo X, Zhu Y, Ye H, Zhang M, Zhang P, Yang L, Wang W, Pan J. PMID: 38513550; PMCID: PMC10973188.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Retromer Proteins Reduced in Down Syndrome and the Dp16 Model: Impact of APP Dose and Preclinical Studies of a γ-Secretase Modulator. Ann Neurol. 2023 08; 94(2):245-258.
Chen XQ, Sawa M, Becker A, Karachentsev D, Zuo X, Rynearson KD, Tanzi RE, Mobley WC. PMID: 37042072.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Reduced synaptic proteins and SNARE complexes in Down syndrome with Alzheimer's disease and the Dp16 mouse Down syndrome model: Impact of APP gene dose. Alzheimers Dement. 2023 05; 19(5):2095-2116.
Chen XQ, Zuo X, Becker A, Head E, Mobley WC. PMID: 36370135; PMCID: PMC10175517.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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AKR1C1 Protects Corneal Epithelial Cells Against Oxidative Stress-Mediated Ferroptosis in Dry Eye. Invest Ophthalmol Vis Sci. 2022 09 01; 63(10):3.
Zuo X, Zeng H, Wang B, Yang X, He D, Wang L, Ouyang H, Yuan J. PMID: 36066316; PMCID: PMC9463717.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Alternative polyadenylation by sequential activation of distal and proximal PolyA sites. Nat Struct Mol Biol. 2022 01; 29(1):21-31.
Tang P, Yang Y, Li G, Huang L, Wen M, Ruan W, Guo X, Zhang C, Zuo X, Luo D, Xu Y, Fu XD, Zhou Y. PMID: 35013598.
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PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Integrated Analysis of the m6A-Related lncRNA Identified lncRNA ABALON/miR-139-3p/NOB1 Axis Was Involved in the Occurrence of Lung Cancer. Cancer Manag Res. 2021; 13:8707-8722.
Liu X, Zuo X, Ma L, Wang Q, Zhu L, Li L, Zhao X. PMID: 34849026; PMCID: PMC8627251.
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PubMed Mentions:
3
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O-GlcNAcylation of TDP-43 suppresses proteinopathies and promotes TDP-43's mRNA splicing activity. EMBO Rep. 2021 06 04; 22(6):e51649.
Zhao MJ, Yao X, Wei P, Zhao C, Cheng M, Zhang D, Xue W, He WT, Xue W, Zuo X, Jiang LL, Luo Z, Song J, Shu WJ, Yuan HY, Liang Y, Sun H, Zhou Y, Zhou Y, Zheng L, Hu HY, Wang J, Du HN. PMID: 33855783; PMCID: PMC8183420.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Melatonin ameliorates oxidative stress-mediated injuries through induction of HO-1 and restores autophagic flux in dry eye. Exp Eye Res. 2021 04; 205:108491.
Wang B, Zuo X, Peng L, Wang X, Zeng H, Zhong J, Li S, Xiao Y, Wang L, Ouyang H, Yuan J. PMID: 33587908.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimals
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TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS. Nat Struct Mol Biol. 2021 02; 28(2):132-142.
Zuo X, Zhou J, Li Y, Wu K, Chen Z, Luo Z, Zhang X, Liang Y, Esteban MA, Zhou Y, Fu XD. PMID: 33398173.
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PubMed Mentions:
112 Fields:
Translation:
HumansAnimalsCells
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Probing the dynamic characteristics of aerosol originated from South Asia biomass burning using POLDER/GRASP satellite data with relevant accessory technique design. Environ Int. 2020 12; 145:106097.
Shi S, Cheng T, Gu X, Guo H, Wu Y, Wang Y, Bao F, Zuo X. PMID: 32911245.
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PHPublic Health
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Active RNA interference in mitochondria. Cell Res. 2021 02; 31(2):219-228.
Gao K, Cheng M, Zuo X, Lin J, Hoogewijs K, Murphy MP, Fu XD, Zhang X. PMID: 32807841; PMCID: PMC8027830.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Spatial and temporal variations of air quality and six air pollutants in China during 2015-2017. Sci Rep. 2019 10 23; 9(1):15201.
Guo H, Gu X, Ma G, Shi S, Wang W, Zuo X, Zhang X. PMID: 31645580; PMCID: PMC6811589.
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11 Fields:
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Phytolith Radiocarbon Dating: A Review of Previous Studies in China and the Current State of the Debate. Front Plant Sci. 2019; 10:1302.
Zuo X, Lu H. PMID: 31681388; PMCID: PMC6807676.
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PubMed Mentions:
2
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An in-depth analysis of glycosylated haemoglobin level, body mass index and left ventricular diastolic dysfunction in patients with type 2 diabetes. BMC Endocr Disord. 2019 Aug 27; 19(1):88.
Zuo X, Liu X, Chen R, Ou H, Lai J, Zhang Y, Yan D. PMID: 31455303; PMCID: PMC6712657.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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The production of reactive oxygen species enhanced with the reduction of menadione by active thioredoxin reductase. Metallomics. 2019 09 01; 11(9):1490-1497.
Li J, Zuo X, Cheng P, Ren X, Sun S, Xu J, Holmgren A, Lu J. PMID: 31359011.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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A retrospective investigation of HLA-B*5801 in hyperuricemia patients in a Han population of China. Pharmacogenet Genomics. 2018 05; 28(5):117-124.
Cheng H, Yan D, Zuo X, Liu J, Liu W, Zhang Y. PMID: 29642234.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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The spatial pattern of farming and factors influencing it during the Peiligang culture period in the middle Yellow River valley, China. Sci Bull (Beijing). 2017 Dec 15; 62(23):1565-1568.
Wang C, Lu H, Gu W, Wu N, Zhang J, Zuo X, Li F, Wang D, Dong Y, Wang S, Liu Y, Bao Y, Hu Y. PMID: 36659473.
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PubMed Mentions:
2 Fields:
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Dating rice remains through phytolith carbon-14 study reveals domestication at the beginning of the Holocene. Proc Natl Acad Sci U S A. 2017 06 20; 114(25):6486-6491.
Zuo X, Lu H, Jiang L, Zhang J, Yang X, Huan X, He K, Wang C, Wu N. PMID: 28559349; PMCID: PMC5488950.
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PubMed Mentions:
32 Fields:
Translation:
Animals
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Radiocarbon dating of prehistoric phytoliths: a preliminary study of archaeological sites in China. Sci Rep. 2016 05 26; 6:26769.
Zuo X, Lu H, Zhang J, Wang C, Sun G, Zheng Y. PMID: 27225903; PMCID: PMC4880898.
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PubMed Mentions:
4 Fields:
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Bulliform Phytolith Research in Wild and Domesticated Rice Paddy Soil in South China. PLoS One. 2015; 10(10):e0141255.
Huan X, Lu H, Wang C, Tang X, Zuo X, Ge Y, He K. PMID: 26488583; PMCID: PMC4619503.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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MicroRNA directly enhances mitochondrial translation during muscle differentiation. Cell. 2014 Jul 31; 158(3):607-19.
Zhang X, Zuo X, Yang B, Li Z, Xue Y, Zhou Y, Huang J, Zhao X, Zhou J, Yan Y, Zhang H, Guo P, Sun H, Guo L, Zhang Y, Fu XD. PMID: 25083871; PMCID: PMC4119298.
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PubMed Mentions:
279 Fields:
Translation:
AnimalsCells