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    Timothy Rodwell

    TitleAssociate Professor In Residence
    SchoolUniversity of California, San Diego
    Address9500 Gilman Drive #0643
    CA La Jolla 92093
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      Collapse Research 
      Collapse Research Activities and Funding
      Culture-free next generation sequencing for rapid detection of drug-resistant tuberculosis
      NIH/NIAID R21AI135756Jan 15, 2018 - Dec 31, 2019
      Role: Principal Investigator
      An Integrated Tabletop Platform for Rapid Detection of XDR-TB in Clinical Samples
      NIH/NIAID R01AI111435Jul 1, 2014 - Jun 30, 2019
      Role: Principal Investigator
      Binational Transmission of Multidrug-Resistant Tuberculosis, California &Mexico
      NIH/NIAID K01AI083784Sep 15, 2009 - Aug 31, 2013
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Seifert M, Georghiou SB, Garfein RS, Catanzaro D, Rodwell T. Impact of fluoroquinolone use on mortality among a cohort of suspected drug-resistant tuberculosis patients. Clin Infect Dis. 2017 May 05. PMID: 28475735.
        View in: PubMed
      2. Georghiou SB, Seifert M, Catanzaro DG, Garfein RS, Rodwell T. Increased Tuberculosis Patient Mortality Associated with Mycobacterium tuberculosis Mutations Conferring Resistance to Second-Line Antituberculous Drugs. J Clin Microbiol. 2017 Jun; 55(6):1928-1937. PMID: 28404672.
        View in: PubMed
      3. Catanzaro DG, Trollip AP, Seifert M, Georghiou SB, Garfein RS, Rodwell T, Catanzaro A, Eisenach KD. Evaluation of the microscopic observation drug susceptibility assay for the detection of first- and second-line drug susceptibility for Mycobacterium tuberculosis. Eur Respir J. 2017 Apr; 49(4). PMID: 28381434.
        View in: PubMed
      4. Bojorquez I, Salazar I, Garfein RS, Cerecer P, Rodwell T. Surveillance or support: The experience of direct observation during tuberculosis treatment. Glob Public Health. 2016 Oct 16; 1-15. PMID: 27748157.
        View in: PubMed
      5. Georghiou SB, Seifert M, Lin SY, Catanzaro D, Garfein RS, Jackson RL, Crudu V, Rodrigues C, Victor TC, Catanzaro A, Rodwell T. Shedding light on the performance of a pyrosequencing assay for drug-resistant tuberculosis diagnosis. BMC Infect Dis. 2016 Aug 31; 16:458. PMID: 27576542; PMCID: PMC5006534.
      6. Kapasi AJ, Dittrich S, González IJ, Rodwell T. Host Biomarkers for Distinguishing Bacterial from Non-Bacterial Causes of Acute Febrile Illness: A Comprehensive Review. PLoS One. 2016; 11(8):e0160278. PMID: 27486746.
        View in: PubMed
      7. Kambli P, Ajbani K, Nikam C, Sadani M, Shetty A, Udwadia Z, Georghiou SB, Rodwell T, Catanzaro A, Rodrigues C. Corrigendum to "Correlating rrs and eis promoter mutations in clinical isolates of Mycobacterium tuberculosis with phenotypic susceptibility levels to the second-line injectables" [Int. J. Mycobacteriol. 5(1) 2016 1-6]. Int J Mycobacteriol. 2016 Sep; 5(3):370-372. PMID: 27847030.
        View in: PubMed
      8. Colman RE, Anderson J, Lemmer D, Lehmkuhl E, Georghiou SB, Heaton H, Wiggins K, Gillece JD, Schupp JM, Catanzaro DG, Crudu V, Cohen T, Rodwell T, Engelthaler DM. Rapid Drug Susceptibility Testing of Drug-Resistant Mycobacterium tuberculosis Isolates Directly from Clinical Samples by Use of Amplicon Sequencing: a Proof-of-Concept Study. J Clin Microbiol. 2016 Aug; 54(8):2058-67. PMID: 27225403; PMCID: PMC4963505.
      9. Berrada ZL, Lin SY, Rodwell T, Nguyen D, Schecter GF, Pham L, Janda JM, Elmaraachli W, Catanzaro A, Desmond E. Rifabutin and rifampin resistance levels and associated rpoB mutations in clinical isolates of Mycobacterium tuberculosis complex. Diagn Microbiol Infect Dis. 2016 Jun; 85(2):177-81. PMID: 27036978; PMCID: PMC4873381 [Available on 06/01/17].
      10. Seifert M, Georghiou SB, Catanzaro D, Rodrigues C, Crudu V, Victor TC, Garfein RS, Catanzaro A, Rodwell T. MTBDRplus and MTBDRsl Assays: Absence of Wild-Type Probe Hybridization and Implications for Detection of Drug-Resistant Tuberculosis. J Clin Microbiol. 2016 Apr; 54(4):912-8. PMID: 26763971; PMCID: PMC4809938 [Available on 10/01/16].
      11. Kambli P, Ajbani K, Nikam C, Sadani M, Shetty A, Udwadia Z, Georghiou SB, Rodwell T, Catanzaro A, Rodrigues C. Correlating rrs and eis promoter mutations in clinical isolates of Mycobacterium tuberculosis with phenotypic susceptibility levels to the second-line injectables. Int J Mycobacteriol. 2016 Mar; 5(1):1-6. PMID: 26927983; PMCID: PMC4863938.
      12. Catanzaro A, Rodwell T, Catanzaro DG, Garfein RS, Jackson RL, Seifert M, Georghiou SB, Trollip A, Groessl E, Hillery N, Crudu V, Victor TC, Rodrigues C, Lin GS, Valafar F, Desmond E, Eisenach K. Performance Comparison of Three Rapid Tests for the Diagnosis of Drug-Resistant Tuberculosis. PLoS One. 2015; 10(8):e0136861. PMID: 26322781; PMCID: PMC4556461.
      13. Avalos E, Catanzaro D, Catanzaro A, Ganiats T, Brodine S, Alcaraz J, Rodwell T. Frequency and geographic distribution of gyrA and gyrB mutations associated with fluoroquinolone resistance in clinical Mycobacterium tuberculosis isolates: a systematic review. PLoS One. 2015; 10(3):e0120470. PMID: 25816236; PMCID: PMC4376704.
      14. Seifert M, Catanzaro D, Catanzaro A, Rodwell T. Genetic mutations associated with isoniazid resistance in Mycobacterium tuberculosis: a systematic review. PLoS One. 2015; 10(3):e0119628. PMID: 25799046; PMCID: PMC4370653.
      15. Kambli P, Ajbani K, Sadani M, Nikam C, Shetty A, Udwadia Z, Georghiou SB, Rodwell T, Catanzaro A, Rodrigues C. Defining multidrug-resistant tuberculosis: correlating GenoType MTBDRplus assay results with minimum inhibitory concentrations. Diagn Microbiol Infect Dis. 2015 May; 82(1):49-53. PMID: 25749461; PMCID: PMC4414878.
      16. Hillery N, Groessl EJ, Trollip A, Catanzaro D, Jackson L, Rodwell T, Garfein RS, Lin SY, Eisenach K, Ganiats TG, Park D, Valafar F, Rodrigues C, Crudu V, Victor TC, Catanzaro A. The Global Consortium for Drug-resistant Tuberculosis Diagnostics (GCDD): design of a multi-site, head-to-head study of three rapid tests to detect extensively drug-resistant tuberculosis. Trials. 2014 Nov 06; 15:434. PMID: 25377177; PMCID: PMC4232628.
      17. Ajbani K, Lin SY, Rodrigues C, Nguyen D, Arroyo F, Kaping J, Jackson L, Garfein RS, Catanzaro D, Eisenach K, Victor TC, Crudu V, Gler MT, Ismail N, Desmond E, Catanzaro A, Rodwell T. Evaluation of pyrosequencing for detecting extensively drug-resistant Mycobacterium tuberculosis among clinical isolates from four high-burden countries. Antimicrob Agents Chemother. 2015 Jan; 59(1):414-20. PMID: 25367911; PMCID: PMC4291380.
      18. Bennett RJ, Brodine S, Waalen J, Moser K, Rodwell T. Prevalence and treatment of latent tuberculosis infection among newly arrived refugees in San Diego County, January 2010-October 2012. Am J Public Health. 2014 Apr; 104(4):e95-e102. PMID: 24524534; PMCID: PMC4025726.
      19. Rodwell T, Valafar F, Douglas J, Qian L, Garfein RS, Chawla A, Torres J, Zadorozhny V, Kim MS, Hoshide M, Catanzaro D, Jackson L, Lin G, Desmond E, Rodrigues C, Eisenach K, Victor TC, Ismail N, Crudu V, Gler MT, Catanzaro A. Predicting extensively drug-resistant Mycobacterium tuberculosis phenotypes with genetic mutations. J Clin Microbiol. 2014 Mar; 52(3):781-9. PMID: 24353002; PMCID: PMC3957771.
      20. Lin SY, Rodwell T, Victor TC, Rider EC, Pham L, Catanzaro A, Desmond EP. Pyrosequencing for rapid detection of extensively drug-resistant Mycobacterium tuberculosis in clinical isolates and clinical specimens. J Clin Microbiol. 2014 Feb; 52(2):475-82. PMID: 24478476; PMCID: PMC3911348.
      21. Bojorquez I, Barnes RF, Flood J, López-Gatell H, Garfein RS, Bäcker CE, Alpuche C, Vinetz JM, Catanzaro A, Kato-Maeda M, Rodwell T. Multidrug-resistant tuberculosis among patients in Baja California, Mexico, and Hispanic patients in California. Am J Public Health. 2013 Jul; 103(7):1301-5. PMID: 23678924; PMCID: PMC3682598.
      22. Shin SS, Gallardo M, Lozada R, Abramovitz D, Burgos JL, Laniado-Laborin R, Rodwell T, Novotny TE, Strathdee SA, Garfein RS. Cigarette-Smoking Intensity and Interferon-Gamma Release Assay Conversion among Persons Who Inject Drugs: A Cohort Study. Pulm Med. 2012; 2012:828106. PMID: 23304497; PMCID: PMC3529865.
      23. Rodwell T, Kapasi AJ, Barnes RF, Moser KS. Factors associated with genotype clustering of Mycobacterium tuberculosis isolates in an ethnically diverse region of southern California, United States. Infect Genet Evol. 2012 Dec; 12(8):1917-25. PMID: 22982156; PMCID: PMC3723456.
      24. Yen YF, Rodwell T, Yen MY, Hsu YH, Chuang P, Li LH, Su LW, Yang YH, Jiang XR, Fang YC, Garfein RS. HIV infection risk among injection drug users in a methadone maintenance treatment program, Taipei, Taiwan 2007-2010. Am J Drug Alcohol Abuse. 2012 Nov; 38(6):544-50. PMID: 22783806; PMCID: PMC4229362.
      25. Velasquez MG, Laniado-Laborin R, Rodwell T, Cerecer P, Lozada R, Cuevas-Mota J, Burgos JL, Garfein RS. Tuberculosis testing among populations with high HIV risk in Tijuana, Baja California, Mexico. Rev Panam Salud Publica. 2012 Jul; 32(1):30-5. PMID: 22910722; PMCID: PMC3711229.
      26. Georghiou SB, Magana M, Garfein RS, Catanzaro DG, Catanzaro A, Rodwell T. Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review. PLoS One. 2012; 7(3):e33275. PMID: 22479378; PMCID: PMC3315572.
      27. Barnes RF, Moore ML, Garfein RS, Brodine S, Strathdee SA, Rodwell T. Trends in mortality of tuberculosis patients in the United States: the long-term perspective. Ann Epidemiol. 2011 Oct; 21(10):791-5. PMID: 21820320; PMCID: PMC3166369.
      28. Rondinelli AJ, Morris MD, Rodwell T, Moser KS, Paida P, Popper ST, Brouwer KC. Under- and over-nutrition among refugees in San Diego County, California. J Immigr Minor Health. 2011 Feb; 13(1):161-8. PMID: 20505992; PMCID: PMC3021711.
      29. Rodwell T, Robertson AM, Aguirre N, Vera A, Anderson CM, Lozada R, Chait L, Schooley RT, Zhang XQ, Strathdee SA. Pandemic (H1N1) 2009 Surveillance in Marginalized Populations, Tijuana, Mexico. Emerg Infect Dis. 2010 Aug; 16(8):1292-5. PMID: 20678328; PMCID: PMC3298300.
      30. Garfein RS, Laniado-Laborin R, Rodwell T, Lozada R, Deiss R, Burgos JL, Cuevas-Mota J, Cerecer P, Moser K, Volker ML, Strathdee SA. Latent tuberculosis among persons at risk for infection with HIV, Tijuana, Mexico. Emerg Infect Dis. 2010 May; 16(5):757-63. PMID: 20409363; PMCID: PMC2953999.
      31. Rodwell T, Kapasi AJ, Moore M, Milian-Suazo F, Harris B, Guerrero LP, Moser K, Strathdee SA, Garfein RS. Tracing the origins of Mycobacterium bovis tuberculosis in humans in the USA to cattle in Mexico using spoligotyping. Int J Infect Dis. 2010 Sep; 14 Suppl 3:e129-35. PMID: 20399697; PMCID: PMC2920372.
      32. Rodwell T, Barnes RF, Moore M, Strathdee SA, Raich A, Moser KS, Garfein RS. HIV-tuberculosis coinfection in Southern California: evaluating disparities in disease burden. Am J Public Health. 2010 Apr 01; 100 Suppl 1:S178-85. PMID: 20147681; PMCID: PMC2837460.
      33. Morris MD, Popper ST, Rodwell T, Brodine SK, Brouwer KC. Healthcare barriers of refugees post-resettlement. J Community Health. 2009 Dec; 34(6):529-38. PMID: 19705264.
        View in: PubMed
      34. Deiss R, Garfein RS, Lozada R, Burgos JL, Brouwer KC, Moser KS, Zuniga ML, Rodwell T, Ojeda VD, Strathdee SA. Influences of cross-border mobility on tuberculosis diagnoses and treatment interruption among injection drug users in Tijuana, Mexico. Am J Public Health. 2009 Aug; 99(8):1491-5. PMID: 19542040; PMCID: PMC2707467.
      35. Deiss RG, Rodwell T, Garfein RS. Tuberculosis and illicit drug use: review and update. Clin Infect Dis. 2009 Jan 01; 48(1):72-82. PMID: 19046064; PMCID: PMC3110742.
      36. Rodwell T, Moore M, Moser KS, Brodine SK, Strathdee SA. Tuberculosis from Mycobacterium bovis in binational communities, United States. Emerg Infect Dis. 2008 Jun; 14(6):909-16. PMID: 18507901; PMCID: PMC2600278.