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Protein Kinase G2 Is Essential for Skeletal Homeostasis and Adaptation to Mechanical Loading in Male but Not Female Mice. J Bone Miner Res. 2023 01; 38(1):171-185.
Kalyanaraman H, Pal China S, Cabriales JA, Moininazeri J, Casteel DE, Garcia JJ, Wong VW, Chen A, Sah RL, Boss GR, Pilz RB. PMID: 36371651; PMCID: PMC9825661.
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AnimalsCells
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Cobinamide is a strong and versatile antioxidant that overcomes oxidative stress in cells, flies, and diabetic mice. PNAS Nexus. 2022 Sep; 1(4):pgac191.
Chang S, Tat J, China SP, Kalyanaraman H, Zhuang S, Chan A, Lai C, Radic Z, Abdel-Rahman EA, Casteel DE, Pilz RB, Ali SS, Boss GR. PMID: 36276587; PMCID: PMC9578022.
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Estradiol overcomes adiponectin-resistance in diabetic mice by regulating skeletal muscle adiponectin receptor 1 expression. Mol Cell Endocrinol. 2022 01 15; 540:111525.
Chattopadhyay S, Joharapurkar A, Das N, Khatoon S, Kushwaha S, Gurjar AA, Singh AK, Shree S, Ahmed MZ, China SP, Pal S, Kumar H, Ramachandran R, Patel V, Trivedi AK, Lahiri A, Jain MR, Chattopadhyay N, Sanyal S. PMID: 34856343.
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HumansAnimalsCells
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Protein kinase G1 regulates bone regeneration and rescues diabetic fracture healing. JCI Insight. 2020 05 07; 5(9).
Schall N, Garcia JJ, Kalyanaraman H, China SP, Lee JJ, Sah RL, Pfeifer A, Pilz RB. PMID: 32315291; PMCID: PMC7253025.
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9 Fields:
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Long acting GLP-1 analog liraglutide ameliorates skeletal muscle atrophy in rodents. Metabolism. 2020 02; 103:154044.
Gurjar AA, Kushwaha S, Chattopadhyay S, Das N, Pal S, China SP, Kumar H, Trivedi AK, Guha R, Chattopadhyay N, Sanyal S. PMID: 31812628.
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Increased Bone Marrow-Specific Adipogenesis by Clofazimine Causes Impaired Fracture Healing, Osteopenia, and Osteonecrosis Without Extraskeletal Effects in Rats. Toxicol Sci. 2019 Nov 01; 172(1):167-180.
Porwal K, Pal S, Tewari D, Pal China S, Singh P, Chandra Tewari M, Prajapati G, Singh P, Cheruvu S, Khan YA, Sanyal S, Gayen JR, Ampapathi R, Mridha AR, Chattopadhyay N. PMID: 31393584.
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A nutraceutical composition containing diosmin and hesperidin has osteogenic and anti-resorptive effects and expands the anabolic window of teriparatide. Biomed Pharmacother. 2019 Oct; 118:109207.
Bhattacharyya S, Pal S, Mohamed R, Singh P, Chattopadhyay S, Pal China S, Porwal K, Sanyal S, Gayen JR, Chattopadhyay N. PMID: 31306971.
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5 Fields:
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The osteogenic effect of liraglutide involves enhanced mitochondrial biogenesis in osteoblasts. Biochem Pharmacol. 2019 06; 164:34-44.
Pal S, Maurya SK, Chattopadhyay S, Pal China S, Porwal K, Kulkarni C, Sanyal S, Sinha RA, Chattopadhyay N. PMID: 30885766; PMCID: PMC7234838.
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Adiponectin signaling and its role in bone metabolism. Cytokine. 2018 12; 112:116-131.
Pal China S, Sanyal S, Chattopadhyay N. PMID: 29937410.
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HumansAnimalsCells
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The wakefulness promoting drug Modafinil causes adenosine receptor-mediated upregulation of receptor activator of nuclear factor κB ligand in osteoblasts: Negative impact of the drug on peak bone accrual in rats. Toxicol Appl Pharmacol. 2018 06 01; 348:22-31.
Pal China S, Pal S, Chattopadhyay S, Porwal K, Mittal M, Sanyal S, Chattopadhyay N. PMID: 29649498.
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5 Fields:
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Stimulation of liver IGF-1 expression promotes peak bone mass achievement in growing rats: a study with pomegranate seed oil. J Nutr Biochem. 2018 02; 52:18-26.
Bachagol D, Joseph GS, Ellur G, Patel K, Aruna P, Mittal M, China SP, Singh RP, Sharan K. PMID: 29121593.
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10 Fields:
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Globular adiponectin reverses osteo-sarcopenia and altered body composition in ovariectomized rats. Bone. 2017 Dec; 105:75-86.
China SP, Pal S, Chattopadhyay S, Porwal K, Kushwaha S, Bhattacharyya S, Mittal M, Gurjar AA, Barbhuyan T, Singh AK, Trivedi AK, Gayen JR, Sanyal S, Chattopadhyay N. PMID: 28811200.
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Guava fruit extract and its triterpene constituents have osteoanabolic effect: Stimulation of osteoblast differentiation by activation of mitochondrial respiration via the Wnt/β-catenin signaling. J Nutr Biochem. 2017 06; 44:22-34.
Porwal K, Pal S, Dev K, China SP, Kumar Y, Singh C, Barbhuyan T, Sinha N, Sanyal S, Trivedi AK, Maurya R, Chattopadhyay N. PMID: 28343085.
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Pharmacological activation of aldehyde dehydrogenase 2 promotes osteoblast differentiation via bone morphogenetic protein-2 and induces bone anabolic effect. Toxicol Appl Pharmacol. 2017 02 01; 316:63-73.
Mittal M, Pal S, China SP, Porwal K, Dev K, Shrivastava R, Raju KS, Rashid M, Trivedi AK, Sanyal S, Wahajuddin M, Bhaduria S, Maurya R, Chattopadhyay N. PMID: 28017615.
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6 Fields:
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BMP signaling is required for adult skeletal homeostasis and mediates bone anabolic action of parathyroid hormone. Bone. 2016 11; 92:132-144.
Khan MP, Khan K, Yadav PS, Singh AK, Nag A, Prasahar P, Mittal M, China SP, Tewari MC, Nagar GK, Tewari D, Trivedi AK, Sanyal S, Bandyopadhyay A, Chattopadhyay N. PMID: 27567726.
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Theophylline, a methylxanthine drug induces osteopenia and alters calciotropic hormones, and prophylactic vitamin D treatment protects against these changes in rats. Toxicol Appl Pharmacol. 2016 Mar 15; 295:12-25.
Pal S, Khan K, China SP, Mittal M, Porwal K, Shrivastava R, Taneja I, Hossain Z, Mandalapu D, Gayen JR, Wahajuddin M, Sharma VL, Trivedi AK, Sanyal S, Bhadauria S, Godbole MM, Gupta SK, Chattopadhyay N. PMID: 26851681.
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10 Fields:
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Ovariectomized Rats with Established Osteopenia have Diminished Mesenchymal Stem Cells in the Bone Marrow and Impaired Homing, Osteoinduction and Bone Regeneration at the Fracture Site. Stem Cell Rev Rep. 2015 Apr; 11(2):309-21.
Tewari D, Khan MP, Sagar N, China SP, Singh AK, Kheruka SC, Barai S, Tewari MC, Nagar GK, Vishwakarma AL, Ogechukwu OE, Bellare JR, Gambhir S, Chattopadhyay N. PMID: 25433862.
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The thiocarbamate disulphide drug, disulfiram induces osteopenia in rats by inhibition of osteoblast function due to suppression of acetaldehyde dehydrogenase activity. Toxicol Sci. 2014 May; 139(1):257-70.
Mittal M, Khan K, Pal S, Porwal K, China SP, Barbhuyan TK, Baghel KS, Rawat T, Sanyal S, Bhadauria S, Sharma VL, Chattopadhyay N. PMID: 24496638.
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Positive skeletal effects of cladrin, a naturally occurring dimethoxydaidzein, in osteopenic rats that were maintained after treatment discontinuation. Osteoporos Int. 2013 Apr; 24(4):1455-70.
Khan K, Sharan K, Swarnkar G, Chakravarti B, Mittal M, Barbhuyan TK, China SP, Khan MP, Nagar GK, Yadav D, Dixit P, Maurya R, Chattopadhyay N. PMID: 22932734.
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9 Fields:
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