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Structure and dynamics determine G protein coupling specificity at a class A GPCR. bioRxiv. 2024 Apr 12.
Casiraghi M, Wang H, Brennan P, Habrian C, Hubner H, Schmidt MF, Maul L, Pani B, Bahriz SM, Xu B, White E, Sunahara RK, Xiang YK, Lefkowitz RJ, Isacoff EY, Nucci N, Gmeiner P, Lerch M, Kobilka BK. PMID: 38586060; PMCID: PMC10996611.
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Author Correction: Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics. Nat Commun. 2023 May 24; 14(1):2992.
Xu X, Shonberg J, Kaindl J, Clark MJ, Stößel A, Maul L, Mayer D, Hübner H, Hirata K, Venkatakrishnan AJ, Dror RO, Kobilka BK, Sunahara RK, Liu X, Gmeiner P. PMID: 37225685; PMCID: PMC10209213.
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Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics. Nat Commun. 2023 04 14; 14(1):2138.
Xu X, Shonberg J, Kaindl J, Clark MJ, Stößel A, Maul L, Mayer D, Hübner H, Hirata K, Venkatakrishnan AJ, Dror RO, Kobilka BK, Sunahara RK, Liu X, Gmeiner P. PMID: 37059717; PMCID: PMC10104803.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Mapping the conformational landscape of the stimulatory heterotrimeric G protein. Nat Struct Mol Biol. 2023 04; 30(4):502-511.
Huang SK, Picard LP, Rahmatullah RSM, Pandey A, Van Eps N, Sunahara RK, Ernst OP, Sljoka A, Prosser RS. PMID: 36997760.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Non-canonical β-adrenergic activation of ERK at endosomes. Nature. 2022 11; 611(7934):173-179.
Kwon Y, Mehta S, Clark M, Walters G, Zhong Y, Lee HN, Sunahara RK, Zhang J. PMID: 36289326; PMCID: PMC10031817.
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PubMed Mentions:
34 Fields:
Translation:
Cells
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Integrative RNA-omics Discovers GNAS Alternative Splicing as a Phenotypic Driver of Splicing Factor-Mutant Neoplasms. Cancer Discov. 2022 03 01; 12(3):836-855.
Wheeler EC, Vora S, Mayer D, Kotini AG, Olszewska M, Park SS, Guccione E, Teruya-Feldstein J, Silverman L, Sunahara RK, Yeo GW, Papapetrou EP. PMID: 34620690; PMCID: PMC8904276.
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18 Fields:
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HumansCells
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Leveraging nonstructural data to predict structures and affinities of protein-ligand complexes. Proc Natl Acad Sci U S A. 2021 12 21; 118(51).
Paggi JM, Belk JA, Hollingsworth SA, Villanueva N, Powers AS, Clark MJ, Chemparathy AG, Tynan JE, Lau TK, Sunahara RK, Dror RO. PMID: 34921117; PMCID: PMC8713799.
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PubMed Mentions:
9 Fields:
Translation:
Cells
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A photoswitchable GPCR-based opsin for presynaptic inhibition. Neuron. 2021 06 02; 109(11):1791-1809.e11.
Copits BA, Gowrishankar R, O'Neill PR, Li JN, Girven KS, Yoo JJ, Meshik X, Parker KE, Spangler SM, Elerding AJ, Brown BJ, Shirley SE, Ma KKL, Vasquez AM, Stander MC, Kalyanaraman V, Vogt SK, Samineni VK, Patriarchi T, Tian L, Gautam N, Sunahara RK, Gereau RW, Bruchas MR. PMID: 33979635; PMCID: PMC8194251.
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PubMed Mentions:
42 Fields:
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HumansAnimalsCells
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Delineating the conformational landscape of the adenosine A2A receptor during G protein coupling. Cell. 2021 04 01; 184(7):1884-1894.e14.
Huang SK, Pandey A, Tran DP, Villanueva NL, Kitao A, Sunahara RK, Sljoka A, Prosser RS. PMID: 33743210; PMCID: PMC10266235.
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PubMed Mentions:
55 Fields:
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HumansCells
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Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR. Cell Res. 2021 05; 31(5):569-579.
Xu X, Kaindl J, Clark MJ, Hübner H, Hirata K, Sunahara RK, Gmeiner P, Kobilka BK, Liu X. PMID: 33093660; PMCID: PMC8089101.
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PubMed Mentions:
53 Fields:
Translation:
Humans
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Structure and selectivity engineering of the M1 muscarinic receptor toxin complex. Science. 2020 07 10; 369(6500):161-167.
Maeda S, Xu J, N Kadji FM, Clark MJ, Zhao J, Tsutsumi N, Aoki J, Sunahara RK, Inoue A, Garcia KC, Kobilka BK. PMID: 32646996; PMCID: PMC7954660.
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PubMed Mentions:
22 Fields:
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AnimalsCells
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Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane. Nature. 2020 08; 584(7819):125-129.
Yin J, Chen KM, Clark MJ, Hijazi M, Kumari P, Bai XC, Sunahara RK, Barth P, Rosenbaum DM. PMID: 32528175; PMCID: PMC7415663.
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PubMed Mentions:
81 Fields:
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HumansCells
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An allosteric modulator binds to a conformational hub in the β2 adrenergic receptor. Nat Chem Biol. 2020 07; 16(7):749-755.
Liu X, Kaindl J, Korczynska M, Stößel A, Dengler D, Stanek M, Hübner H, Clark MJ, Mahoney J, Matt RA, Xu X, Hirata K, Shoichet BK, Sunahara RK, Kobilka BK, Gmeiner P. PMID: 32483378; PMCID: PMC7816728.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Structure of an endosomal signaling GPCR-G protein-β-arrestin megacomplex. Nat Struct Mol Biol. 2019 12; 26(12):1123-1131.
Nguyen AH, Thomsen ARB, Cahill TJ, Huang R, Huang LY, Marcink T, Clarke OB, Heissel S, Masoudi A, Ben-Hail D, Samaan F, Dandey VP, Tan YZ, Hong C, Mahoney JP, Triest S, Little J, Chen X, Sunahara R, Steyaert J, Molina H, Yu Z, des Georges A, Lefkowitz RJ. PMID: 31740855; PMCID: PMC7108872.
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PubMed Mentions:
91 Fields:
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HumansAnimalsCells
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Publisher Correction: Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist. Nat Chem Biol. 2019 02; 15(2):205.
Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, Kobilka BK. PMID: 30504785.
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Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists. Proc Natl Acad Sci U S A. 2018 11 20; 115(47):12046-12050.
Liu H, Hofmann J, Fish I, Schaake B, Eitel K, Bartuschat A, Kaindl J, Rampp H, Banerjee A, Hübner H, Clark MJ, Vincent SG, Fisher JT, Heinrich MR, Hirata K, Liu X, Sunahara RK, Shoichet BK, Kobilka BK, Gmeiner P. PMID: 30404914; PMCID: PMC6255194.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist. Nat Chem Biol. 2018 11; 14(11):1059-1066.
Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, Kobilka BK. PMID: 30327561; PMCID: PMC6197491.
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PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCells
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Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment. J Biol Chem. 2018 11 16; 293(46):17875-17887.
Valnohova J, Kowalski-Jahn M, Sunahara RK, Schulte G. PMID: 30237173; PMCID: PMC6240854.
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PubMed Mentions:
11 Fields:
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HumansCells
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Rules of Engagement: GPCRs and G Proteins. ACS Pharmacol Transl Sci. 2018 Nov 09; 1(2):73-83.
Glukhova A, Draper-Joyce CJ, Sunahara RK, Christopoulos A, Wootten D, Sexton PM. PMID: 32219204; PMCID: PMC7089011.
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PubMed Mentions:
61
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Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor. Elife. 2018 06 22; 7.
Livingston KE, Mahoney JP, Manglik A, Sunahara RK, Traynor JR. PMID: 29932421; PMCID: PMC6042960.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Mechanistic insights into allosteric regulation of the A2A adenosine G protein-coupled receptor by physiological cations. Nat Commun. 2018 04 10; 9(1):1372.
Ye L, Neale C, Sljoka A, Lyda B, Pichugin D, Tsuchimura N, Larda ST, Pomès R, García AE, Ernst OP, Sunahara RK, Prosser RS. PMID: 29636462; PMCID: PMC5893540.
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PubMed Mentions:
68 Fields:
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HumansAnimalsCells
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Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor. Proc Natl Acad Sci U S A. 2018 03 06; 115(10):E2419-E2428.
Korczynska M, Clark MJ, Valant C, Xu J, Moo EV, Albold S, Weiss DR, Torosyan H, Huang W, Kruse AC, Lyda BR, May LT, Baltos JA, Sexton PM, Kobilka BK, Christopoulos A, Shoichet BK, Sunahara RK. PMID: 29453275; PMCID: PMC5877965.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
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Structure-Based Design and Discovery of New M2 Receptor Agonists. J Med Chem. 2017 11 22; 60(22):9239-9250.
Fish I, Stößel A, Eitel K, Valant C, Albold S, Huebner H, Möller D, Clark MJ, Sunahara RK, Christopoulos A, Shoichet BK, Gmeiner P. PMID: 29094937; PMCID: PMC5836741.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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ER/K linked GPCR-G protein fusions systematically modulate second messenger response in cells. Sci Rep. 2017 08 10; 7(1):7749.
Malik RU, Dysthe M, Ritt M, Sunahara RK, Sivaramakrishnan S. PMID: 28798477; PMCID: PMC5552854.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK. Sci Signal. 2017 Jun 20; 10(484).
O'Hayre M, Eichel K, Avino S, Zhao X, Steffen DJ, Feng X, Kawakami K, Aoki J, Messer K, Sunahara R, Inoue A, von Zastrow M, Gutkind JS. PMID: 28634209; PMCID: PMC5751434.
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PubMed Mentions:
96 Fields:
Translation:
HumansAnimalsCells
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Purification of family B G protein-coupled receptors using nanodiscs: Application to human glucagon-like peptide-1 receptor. PLoS One. 2017; 12(6):e0179568.
Cai Y, Liu Y, Culhane KJ, DeVree BT, Yang Y, Sunahara RK, Yan ECY. PMID: 28609478; PMCID: PMC5469476.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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In Situ Reconstitution of the Adenosine A2A Receptor in Spontaneously Formed Synthetic Liposomes. J Am Chem Soc. 2017 03 15; 139(10):3607-3610.
Brea RJ, Cole CM, Lyda BR, Ye L, Prosser RS, Sunahara RK, Devaraj NK. PMID: 28263576; PMCID: PMC5702554.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Mechanistic insights into GPCR-G protein interactions. Curr Opin Struct Biol. 2016 12; 41:247-254.
Mahoney JP, Sunahara RK. PMID: 27871057; PMCID: PMC5363957.
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PubMed Mentions:
65 Fields:
Translation:
HumansCells
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GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling. Cell. 2016 Aug 11; 166(4):907-919.
Thomsen ARB, Plouffe B, Cahill TJ, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ. PMID: 27499021; PMCID: PMC5418658.
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PubMed Mentions:
253 Fields:
Translation:
HumansCells
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Allosteric coupling from G protein to the agonist-binding pocket in GPCRs. Nature. 2016 07 07; 535(7610):182-6.
DeVree BT, Mahoney JP, Vélez-Ruiz GA, Rasmussen SG, Kuszak AJ, Edwald E, Fung JJ, Manglik A, Masureel M, Du Y, Matt RA, Pardon E, Steyaert J, Kobilka BK, Sunahara RK. PMID: 27362234; PMCID: PMC5702553.
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PubMed Mentions:
138 Fields:
Translation:
HumansCells
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The Molecular Pharmacology of G Protein Signaling Then and Now: A Tribute to Alfred G. Gilman. Mol Pharmacol. 2016 May; 89(5):585-92.
Sunahara RK, Insel PA. PMID: 26984025; PMCID: PMC11037445.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Pharmacological chaperone for α-crystallin partially restores transparency in cataract models. Science. 2015 Nov 06; 350(6261):674-7.
Makley LN, McMenimen KA, DeVree BT, Goldman JW, McGlasson BN, Rajagopal P, Dunyak BM, McQuade TJ, Thompson AD, Sunahara R, Klevit RE, Andley UP, Gestwicki JE. PMID: 26542570; PMCID: PMC4725592.
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PubMed Mentions:
110 Fields:
Translation:
HumansAnimalsCells
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Electron Microscopic Visualization of Protein Assemblies on Flattened DNA Origami. ACS Nano. 2015 Jul 28; 9(7):7133-41.
Mallik L, Dhakal S, Nichols J, Mahoney J, Dosey AM, Jiang S, Sunahara RK, Skiniotis G, Walter NG. PMID: 26149412; PMCID: PMC5835357.
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PubMed Mentions:
9 Fields:
Translation:
Cells
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SIGNAL TRANSDUCTION. Structural basis for nucleotide exchange in heterotrimeric G proteins. Science. 2015 Jun 19; 348(6241):1361-5.
Dror RO, Mildorf TJ, Hilger D, Manglik A, Borhani DW, Arlow DH, Philippsen A, Villanueva N, Yang Z, Lerch MT, Hubbell WL, Kobilka BK, Sunahara RK, Shaw DE. PMID: 26089515; PMCID: PMC4968074.
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PubMed Mentions:
149 Fields:
Translation:
HumansCells
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A thermostable bacterial cocaine esterase rapidly eliminates cocaine from brain in nonhuman primates. Transl Psychiatry. 2014 Jul 01; 4:e407.
Howell LL, Nye JA, Stehouwer JS, Voll RJ, Mun J, Narasimhan D, Nichols J, Sunahara R, Goodman MM, Carroll FI, Woods JH. PMID: 24984194; PMCID: PMC4119218.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Detection of G protein-selective G protein-coupled receptor (GPCR) conformations in live cells. J Biol Chem. 2013 Jun 14; 288(24):17167-78.
Malik RU, Ritt M, DeVree BT, Neubig RR, Sunahara RK, Sivaramakrishnan S. PMID: 23629648; PMCID: PMC3682522.
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PubMed Mentions:
41 Fields:
Translation:
HumansCells
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Conformational biosensors reveal GPCR signalling from endosomes. Nature. 2013 Mar 28; 495(7442):534-8.
Irannejad R, Tomshine JC, Tomshine JR, Chevalier M, Mahoney JP, Steyaert J, Rasmussen SG, Sunahara RK, El-Samad H, Huang B, von Zastrow M. PMID: 23515162; PMCID: PMC3835555.
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PubMed Mentions:
386 Fields:
Translation:
HumansCells
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Calcium-dependent ligand binding and G-protein signaling of family B GPCR parathyroid hormone 1 receptor purified in nanodiscs. ACS Chem Biol. 2013 Mar 15; 8(3):617-25.
Mitra N, Liu Y, Liu J, Serebryany E, Mooney V, DeVree BT, Sunahara RK, Yan EC. PMID: 23237450; PMCID: PMC4015634.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Identification of GPCR-interacting cytosolic proteins using HDL particles and mass spectrometry-based proteomic approach. PLoS One. 2013; 8(1):e54942.
Chung KY, Day PW, Vélez-Ruiz G, Sunahara RK, Kobilka BK. PMID: 23372797; PMCID: PMC3556083.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Repeated administration of a mutant cocaine esterase: effects on plasma cocaine levels, cocaine-induced cardiovascular activity, and immune responses in rhesus monkeys. J Pharmacol Exp Ther. 2012 Jul; 342(1):205-13.
Collins GT, Brim RL, Noon KR, Narasimhan D, Lukacs NW, Sunahara RK, Woods JH, Ko MC. PMID: 22518021; PMCID: PMC3383034.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Cell permeable cocaine esterases constructed by chemical conjugation and genetic recombination. Mol Pharm. 2012 May 07; 9(5):1361-73.
Lee TY, Park YS, Garcia GA, Sunahara RK, Woods JH, Yang VC. PMID: 22404344; PMCID: PMC3349905.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Crystal structure of the µ-opioid receptor bound to a morphinan antagonist. Nature. 2012 Mar 21; 485(7398):321-6.
Manglik A, Kruse AC, Kobilka TS, Thian FS, Mathiesen JM, Sunahara RK, Pardo L, Weis WI, Kobilka BK, Granier S. PMID: 22437502; PMCID: PMC3523197.
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PubMed Mentions:
636 Fields:
Translation:
AnimalsCells
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Bacterial cocaine esterase: a protein-based therapy for cocaine overdose and addiction. Future Med Chem. 2012 Feb; 4(2):137-50.
Narasimhan D, Woods JH, Sunahara RK. PMID: 22300094; PMCID: PMC3290992.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Long-lasting effects of a PEGylated mutant cocaine esterase (CocE) on the reinforcing and discriminative stimulus effects of cocaine in rats. Neuropsychopharmacology. 2012 Apr; 37(5):1092-103.
Collins GT, Narasimhan D, Cunningham AR, Zaks ME, Nichols J, Ko MC, Sunahara RK, Woods JH. PMID: 21993206; PMCID: PMC3306869.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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The fate of bacterial cocaine esterase (CocE): an in vivo study of CocE-mediated cocaine hydrolysis, CocE pharmacokinetics, and CocE elimination. J Pharmacol Exp Ther. 2012 Jan; 340(1):83-95.
Brim RL, Noon KR, Collins GT, Stein A, Nichols J, Narasimhan D, Ko MC, Woods JH, Sunahara RK. PMID: 21990608; PMCID: PMC3251018.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Conformational changes in the G protein Gs induced by the β2 adrenergic receptor. Nature. 2011 Sep 28; 477(7366):611-5.
Chung KY, Rasmussen SG, Liu T, Li S, DeVree BT, Chae PS, Calinski D, Kobilka BK, Woods VL, Sunahara RK. PMID: 21956331; PMCID: PMC3448949.
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PubMed Mentions:
197 Fields:
Translation:
HumansAnimalsCells
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Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex. Proc Natl Acad Sci U S A. 2011 Sep 20; 108(38):16086-91.
Westfield GH, Rasmussen SG, Su M, Dutta S, DeVree BT, Chung KY, Calinski D, Velez-Ruiz G, Oleskie AN, Pardon E, Chae PS, Liu T, Li S, Woods VL, Steyaert J, Kobilka BK, Sunahara RK, Skiniotis G. PMID: 21914848; PMCID: PMC3179071.
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PubMed Mentions:
134 Fields:
Translation:
AnimalsCells
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Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time. Mol Pharmacol. 2011 Dec; 80(6):1056-65.
Narasimhan D, Collins GT, Nance MR, Nichols J, Edwald E, Chan J, Ko MC, Woods JH, Tesmer JJ, Sunahara RK. PMID: 21890748; PMCID: PMC3228533.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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The ability of bacterial cocaine esterase to hydrolyze cocaine metabolites and their simultaneous quantification using high-performance liquid chromatography-tandem mass spectrometry. Mol Pharmacol. 2011 Dec; 80(6):1119-27.
Brim RL, Noon KR, Collins GT, Nichols J, Narasimhan D, Sunahara RK, Woods JH. PMID: 21885621; PMCID: PMC3228532.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Evaluation of the hydrolytic activity of a long-acting mutant bacterial cocaine in the presence of commonly co-administered drugs. Drug Alcohol Depend. 2011 Dec 15; 119(3):224-8.
Brim RL, Noon KR, Nichols J, Narasimhan D, Woods JH, Sunahara RK. PMID: 21775073; PMCID: PMC3217061.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Crystal structure of the β2 adrenergic receptor-Gs protein complex. Nature. 2011 Jul 19; 477(7366):549-55.
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK. PMID: 21772288; PMCID: PMC3184188.
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PubMed Mentions:
1430 Fields:
Translation:
AnimalsCells
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Effects of a long-acting mutant bacterial cocaine esterase on acute cocaine toxicity in rats. Drug Alcohol Depend. 2011 Nov 01; 118(2-3):158-65.
Collins GT, Zaks ME, Cunningham AR, St Clair C, Nichols J, Narasimhan D, Ko MC, Sunahara RK, Woods JH. PMID: 21481548; PMCID: PMC3150623.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase. Neuropsychopharmacology. 2011 Apr; 36(5):1047-59.
Collins GT, Carey KA, Narasimhan D, Nichols J, Berlin AA, Lukacs NW, Sunahara RK, Woods JH, Ko MC. PMID: 21289605; PMCID: PMC3076304.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Nature. 2011 Jan 13; 469(7329):175-80.
Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, Chae PS, Devree BT, Rosenbaum DM, Thian FS, Kobilka TS, Schnapp A, Konetzki I, Sunahara RK, Gellman SH, Pautsch A, Steyaert J, Weis WI, Kobilka BK. PMID: 21228869; PMCID: PMC3058308.
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PubMed Mentions:
770 Fields:
Translation:
HumansAnimalsCells
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Structure and function of an irreversible agonist-β(2) adrenoceptor complex. Nature. 2011 Jan 13; 469(7329):236-40.
Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, Caffrey M, Gmeiner P, Kobilka BK. PMID: 21228876; PMCID: PMC3074335.
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PubMed Mentions:
345 Fields:
Translation:
HumansCells
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Reconstitution of G protein-coupled receptors into a model bilayer system: reconstituted high-density lipoprotein particles. Methods Mol Biol. 2011; 756:167-82.
Vélez-Ruiz GA, Sunahara RK. PMID: 21870225; PMCID: PMC3582183.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Structural analysis of thermostabilizing mutations of cocaine esterase. Protein Eng Des Sel. 2010 Jul; 23(7):537-47.
Narasimhan D, Nance MR, Gao D, Ko MC, Macdonald J, Tamburi P, Yoon D, Landry DM, Woods JH, Zhan CG, Tesmer JJ, Sunahara RK. PMID: 20436035; PMCID: PMC2920302.
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PubMed Mentions:
26 Fields:
Translation:
Cells
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A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse. Mol Pharmacol. 2010 Apr; 77(4):593-600.
Brim RL, Nance MR, Youngstrom DW, Narasimhan D, Zhan CG, Tesmer JJ, Sunahara RK, Woods JH. PMID: 20086035; PMCID: PMC2845945.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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PEGylation of bacterial cocaine esterase for protection against protease digestion and immunogenicity. J Control Release. 2010 Mar 03; 142(2):174-9.
Park JB, Kwon YM, Lee TY, Brim R, Ko MC, Sunahara RK, Woods JH, Yang VC. PMID: 19857534; PMCID: PMC2824037.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Prevention and reversal by cocaine esterase of cocaine-induced cardiovascular effects in rats. Drug Alcohol Depend. 2010 Jan 15; 106(2-3):219-29.
Wood SK, Narasimhan D, Cooper Z, Sunahara RK, Woods JH. PMID: 19800183; PMCID: PMC3349347.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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Ligand-regulated oligomerization of beta(2)-adrenoceptors in a model lipid bilayer. EMBO J. 2009 Nov 04; 28(21):3315-28.
Fung JJ, Deupi X, Pardo L, Yao XJ, Velez-Ruiz GA, Devree BT, Sunahara RK, Kobilka BK. PMID: 19763081; PMCID: PMC2748299.
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PubMed Mentions:
74 Fields:
Translation:
HumansCells
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Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats. J Pharmacol Exp Ther. 2009 Nov; 331(2):445-55.
Collins GT, Brim RL, Narasimhan D, Ko MC, Sunahara RK, Zhan CG, Woods JH. PMID: 19710369; PMCID: PMC2775252.
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PubMed Mentions:
33 Fields:
Translation:
Animals
-
Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2. J Biol Chem. 2009 Sep 25; 284(39):26732-41.
Kuszak AJ, Pitchiaya S, Anand JP, Mosberg HI, Walter NG, Sunahara RK. PMID: 19542234; PMCID: PMC2785361.
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PubMed Mentions:
86 Fields:
Translation:
HumansAnimalsCells
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The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex. Proc Natl Acad Sci U S A. 2009 Jun 09; 106(23):9501-6.
Yao XJ, Vélez Ruiz G, Whorton MR, Rasmussen SG, DeVree BT, Deupi X, Sunahara RK, Kobilka B. PMID: 19470481; PMCID: PMC2685739.
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PubMed Mentions:
134 Fields:
Translation:
HumansCells
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Effects of cocaine esterase following its repeated administration with cocaine in mice. Drug Alcohol Depend. 2009 May 01; 101(3):202-9.
Ko MC, Narasimhan D, Berlin AA, Lukacs NW, Sunahara RK, Woods JH. PMID: 19217723; PMCID: PMC2693214.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimals
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Proerectile effects of dopamine D2-like agonists are mediated by the D3 receptor in rats and mice. J Pharmacol Exp Ther. 2009 Apr; 329(1):210-7.
Collins GT, Truccone A, Haji-Abdi F, Newman AH, Grundt P, Rice KC, Husbands SM, Greedy BM, Enguehard-Gueiffier C, Gueiffier A, Chen J, Wang S, Katz JL, Grandy DK, Sunahara RK, Woods JH. PMID: 19136638; PMCID: PMC2670592.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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A bacterial cocaine esterase protects against cocaine-induced epileptogenic activity and lethality. Ann Emerg Med. 2009 Sep; 54(3):409-20.
Jutkiewicz EM, Baladi MG, Cooper ZD, Narasimhan D, Sunahara RK, Woods JH. PMID: 19013687; PMCID: PMC3357128.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity. Mol Pharmacol. 2009 Feb; 75(2):318-23.
Gao D, Narasimhan DL, Macdonald J, Brim R, Ko MC, Landry DW, Woods JH, Sunahara RK, Zhan CG. PMID: 18987161; PMCID: PMC2684895.
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PubMed Mentions:
50 Fields:
Translation:
Animals
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Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer. J Biol Chem. 2008 Feb 15; 283(7):4387-94.
Whorton MR, Jastrzebska B, Park PS, Fotiadis D, Engel A, Palczewski K, Sunahara RK. PMID: 18033822; PMCID: PMC2651572.
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PubMed Mentions:
136 Fields:
Translation:
HumansAnimalsCells
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Detection of g protein coupled receptor mediated adenylyl cyclase activity by capillary electrophoresis using fluorescently labeled ATP. Anal Chem. 2007 Oct 01; 79(19):7534-9.
Cunliffe JM, Sunahara RK, Kennedy RT. PMID: 17718540.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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A CE assay for the detection of agonist-stimulated adenylyl cyclase activity. Electrophoresis. 2007 Jun; 28(12):1913-20.
Cunliffe JM, Whorton MR, Sunahara RK, Kennedy RT. PMID: 17480040.
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PubMed Mentions: Fields:
Translation:
CellsPHPublic Health
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Fluorescence-based adenylyl cyclase assay adaptable to high throughput screening. Comb Chem High Throughput Screen. 2007 May; 10(4):289-98.
Vadakkadathmeethal K, Cunliffe JM, Swift J, Kennedy RT, Neubig RR, Sunahara RK. PMID: 17506713.
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PubMed Mentions: Fields:
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A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc Natl Acad Sci U S A. 2007 May 01; 104(18):7682-7.
Whorton MR, Bokoch MP, Rasmussen SG, Huang B, Zare RN, Kobilka B, Sunahara RK. PMID: 17452637; PMCID: PMC1863461.
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PubMed Mentions:
309 Fields:
Translation:
HumansAnimalsCells
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Under the microscope: single molecule symposium at the University of Michigan, 2006. Biopolymers. 2007 Feb 05; 85(2):106-14.
Walter NG, Meiners JC, Meyhofer E, Neubig RR, Sunahara RK, Perkins NC, Steel DG, Swanson JA. PMID: 17080420.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5. Proc Natl Acad Sci U S A. 2007 Feb 06; 104(6):1805-10.
Benson MD, Li QJ, Kieckhafer K, Dudek D, Whorton MR, Sunahara RK, Iñiguez-Lluhí JA, Martens JR. PMID: 17261810; PMCID: PMC1794304.
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PubMed Mentions:
75 Fields:
Translation:
HumansAnimalsCells
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N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells. Mol Pharmacol. 2007 Apr; 71(4):1040-50.
Bodenstein J, Sunahara RK, Neubig RR. PMID: 17220356.
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PubMed Mentions:
50 Fields:
Translation:
HumansCells
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Cocaine esterase: interactions with cocaine and immune responses in mice. J Pharmacol Exp Ther. 2007 Feb; 320(2):926-33.
Ko MC, Bowen LD, Narasimhan D, Berlin AA, Lukacs NW, Sunahara RK, Cooper ZD, Woods JH. PMID: 17114567.
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PubMed Mentions:
37 Fields:
Translation:
Animals
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Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay. Mol Pharmacol. 2007 Jan; 71(1):169-75.
Roman DL, Talbot JN, Roof RA, Sunahara RK, Traynor JR, Neubig RR. PMID: 17012620.
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PubMed Mentions:
70 Fields:
Translation:
Cells
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Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase. Mol Pharmacol. 2006 Dec; 70(6):1885-91.
Cooper ZD, Narasimhan D, Sunahara RK, Mierzejewski P, Jutkiewicz EM, Larsen NA, Wilson IA, Landry DW, Woods JH. PMID: 16968810.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins. Chem Biol Drug Des. 2006 Apr; 67(4):266-74.
Roof RA, Jin Y, Roman DL, Sunahara RK, Ishii M, Mosberg HI, Neubig RR. PMID: 16629824.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Detection of adenylyl cyclase activity using a fluorescent ATP substrate and capillary electrophoresis. Anal Chem. 2006 Mar 15; 78(6):1731-8.
Cunliffe JM, Sunahara RK, Kennedy RT. PMID: 16536404.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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ARF6 activation by Galpha q signaling: Galpha q forms molecular complexes with ARNO and ARF6. Cell Signal. 2006 Nov; 18(11):1988-94.
Giguère P, Rochdi MD, Laroche G, Dupré E, Whorton MR, Sunahara RK, Claing A, Dupuis G, Parent JL. PMID: 16650966.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Regulation of cytochrome P450 2E1 by heat shock protein 90-dependent stabilization and CHIP-dependent proteasomal degradation. Biochemistry. 2005 Dec 13; 44(49):16333-40.
Morishima Y, Peng HM, Lin HL, Hollenberg PF, Sunahara RK, Osawa Y, Pratt WB. PMID: 16331994.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Cloning and characterization of the G protein betagamma subunits from Trichoplusia ni (High Five cells). Insect Biochem Mol Biol. 2005 Apr; 35(4):333-45.
Vadakkadathmeethal K, Felczak A, Davignon I, Collins J, Sunahara RK. PMID: 15763469.
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Translation:
HumansAnimalsCells
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Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities. J Lipid Res. 2005 Jun; 46(6):1239-47.
Draganov DI, Teiber JF, Speelman A, Osawa Y, Sunahara R, La Du BN. PMID: 15772423.
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PubMed Mentions:
236 Fields:
Translation:
HumansCells
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Nitric oxide-dependent allosteric inhibitory role of a second nucleotide binding site in soluble guanylyl cyclase. J Biol Chem. 2005 Mar 25; 280(12):11513-9.
Chang FJ, Lemme S, Sun Q, Sunahara RK, Beuve A. PMID: 15649897.
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PubMed Mentions:
24 Fields:
Translation:
Cells
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Real-time detection of basal and stimulated G protein GTPase activity using fluorescent GTP analogues. J Biol Chem. 2005 Mar 04; 280(9):7712-9.
Jameson EE, Roof RA, Whorton MR, Mosberg HI, Sunahara RK, Neubig RR, Kennedy RT. PMID: 15613467.
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PubMed Mentions:
17 Fields:
Translation:
Cells
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Affinity assays using fluorescence anisotropy with capillary electrophoresis separation. Anal Chem. 2004 Dec 15; 76(24):7380-6.
Whelan RJ, Sunahara RK, Neubig RR, Kennedy RT. PMID: 15595883.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Zinc inhibition of adenylyl cyclase correlates with conformational changes in the enzyme. Cell Signal. 2004 Oct; 16(10):1177-85.
Klein C, Heyduk T, Sunahara RK. PMID: 15240012.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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Differentially regulated expression of endogenous RGS4 and RGS7. J Biol Chem. 2004 Jan 23; 279(4):2593-9.
Krumins AM, Barker SA, Huang C, Sunahara RK, Yu K, Wilkie TM, Gold SJ, Mumby SM. PMID: 14604980.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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The hsp90 cochaperone p23 is the limiting component of the multiprotein hsp90/hsp70-based chaperone system in vivo where it acts to stabilize the client protein: hsp90 complex. J Biol Chem. 2003 Dec 05; 278(49):48754-63.
Morishima Y, Kanelakis KC, Murphy PJ, Lowe ER, Jenkins GJ, Osawa Y, Sunahara RK, Pratt WB. PMID: 14507910.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Detection of G proteins by affinity probe capillary electrophoresis using a fluorescently labeled GTP analogue. Anal Chem. 2003 Aug 15; 75(16):4297-304.
Jameson EE, Cunliffe JM, Neubig RR, Sunahara RK, Kennedy RT. PMID: 14632149.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Isoforms of mammalian adenylyl cyclase: multiplicities of signaling. Mol Interv. 2002 Jun; 2(3):168-84.
Sunahara RK, Taussig R. PMID: 14993377.
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PubMed Mentions:
141 Fields:
Translation:
HumansAnimalsCells
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Zinc inhibition of cAMP signaling. J Biol Chem. 2002 Apr 05; 277(14):11859-65.
Klein C, Sunahara RK, Hudson TY, Heyduk T, Howlett AC. PMID: 11805091.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Expression, purification, and assay of cytosolic (catalytic) domains of membrane-bound mammalian adenylyl cyclases. Methods Enzymol. 2002; 345:127-40.
Hatley ME, Gilman AG, Sunahara RK. PMID: 11665600.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Crystallization of complex between soluble domains of adenylyl cyclase and activated Gs alpha. Methods Enzymol. 2002; 345:198-206.
Tesmer JJ, Sunahara RK, Fancy DA, Gilman AG, Sprang SR. PMID: 11665605.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Cloning and mitochondrial localization of full-length D-AKAP2, a protein kinase A anchoring protein. Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):3220-5.
Wang L, Sunahara RK, Krumins A, Perkins G, Crochiere ML, Mackey M, Bell S, Ellisman MH, Taylor SS. PMID: 11248059; PMCID: PMC30634.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Isolation and characterization of constitutively active mutants of mammalian adenylyl cyclase. J Biol Chem. 2000 Dec 08; 275(49):38626-32.
Hatley ME, Benton BK, Xu J, Manfredi JP, Gilman AG, Sunahara RK. PMID: 10982815.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Molecular basis for P-site inhibition of adenylyl cyclase. Biochemistry. 2000 Nov 28; 39(47):14464-71.
Tesmer JJ, Dessauer CW, Sunahara RK, Murray LD, Johnson RA, Gilman AG, Sprang SR. PMID: 11087399.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Two-metal-Ion catalysis in adenylyl cyclase. Science. 1999 Jul 30; 285(5428):756-60.
Tesmer JJ, Sunahara RK, Johnson RA, Gosselin G, Gilman AG, Sprang SR. PMID: 10427002.
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PubMed Mentions:
111 Fields:
Translation:
AnimalsCells
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Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases. J Biol Chem. 1998 Jun 26; 273(26):16332-8.
Sunahara RK, Beuve A, Tesmer JJ, Sprang SR, Garbers DL, Gilman AG. PMID: 9632695.
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PubMed Mentions:
75 Fields:
Translation:
AnimalsCells
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Crystal structure of the adenylyl cyclase activator Gsalpha. Science. 1997 Dec 12; 278(5345):1943-7.
Sunahara RK, Tesmer JJ, Gilman AG, Sprang SR. PMID: 9395396.
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PubMed Mentions:
105 Fields:
Translation:
Cells
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Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS. Science. 1997 Dec 12; 278(5345):1907-16.
Tesmer JJ, Sunahara RK, Gilman AG, Sprang SR. PMID: 9417641.
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PubMed Mentions:
241 Fields:
Translation:
Cells
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Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas. Neuroscience. 1997 Oct; 80(4):1171-85.
Svenningsson P, Le Moine C, Kull B, Sunahara R, Bloch B, Fredholm BB. PMID: 9284069.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Interaction of Gsalpha with the cytosolic domains of mammalian adenylyl cyclase. J Biol Chem. 1997 Aug 29; 272(35):22265-71.
Sunahara RK, Dessauer CW, Whisnant RE, Kleuss C, Gilman AG. PMID: 9268375.
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PubMed Mentions:
50 Fields:
Translation:
Cells
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cAMP induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle. Am J Physiol. 1997 Jul; 273(1 Pt 2):H317-23.
Durante W, Christodoulides N, Cheng K, Peyton KJ, Sunahara RK, Schafer AI. PMID: 9249506.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Complexity and diversity of mammalian adenylyl cyclases. Annu Rev Pharmacol Toxicol. 1996; 36:461-80.
Sunahara RK, Dessauer CW, Gilman AG. PMID: 8725398.
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PubMed Mentions:
170 Fields:
Translation:
HumansAnimalsCells
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Receptor-receptor link in membranes revealed by ligand competition: example for dopamine D1 and D2 receptors. Synapse. 1994 May; 17(1):62-4.
Seeman P, Sunahara RK, Niznik HB. PMID: 8042146.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20. Mol Pharmacol. 1993 Jun; 43(6):894-901.
Demchyshyn LL, Srikant CB, Sunahara RK, Kent G, Seeman P, Van Tol HH, Panetta R, Patel YC, Niznik HB. PMID: 8100352.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Exclusion of close linkage of Tourette's syndrome to D1 dopamine receptor. Am J Psychiatry. 1993 Mar; 150(3):449-53.
Gelernter J, Kennedy JL, Grandy DK, Zhou QY, Civelli O, Pauls DL, Pakstis A, Kurlan R, Sunahara RK, Niznik HB, et al. PMID: 8434661.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Schizophrenia: dopamine D1 receptor sequence is normal, but has DNA polymorphisms. Neuropsychopharmacology. 1993 Feb; 8(2):131-5.
Ohara K, Ulpian C, Seeman P, Sunahara RK, Van Tol HH, Niznik HB. PMID: 8471124.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Serotonin receptor cDNA cloned from Lymnaea stagnalis. Proc Natl Acad Sci U S A. 1993 Jan 01; 90(1):11-5.
Sugamori KS, Sunahara RK, Guan HC, Bulloch AG, Tensen CP, Seeman P, Niznik HB, Van Tol HH. PMID: 8093556; PMCID: PMC45589.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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The cloned dopamine D2 receptor reveals different densities for dopamine receptor antagonist ligands. Implications for human brain positron emission tomography. Eur J Pharmacol. 1992 Oct 01; 227(2):139-46.
Seeman P, Guan HC, Civelli O, Van Tol HH, Sunahara RK, Niznik HB. PMID: 1358662.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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A human serotonin 1D receptor variant (5HT1D beta) encoded by an intronless gene on chromosome 6. Proc Natl Acad Sci U S A. 1992 Jun 15; 89(12):5522-6.
Demchyshyn L, Sunahara RK, Miller K, Teitler M, Hoffman BJ, Kennedy JL, Seeman P, Van Tol HH, Niznik HB. PMID: 1351684; PMCID: PMC49324.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Visualization of dopamine D1, D2 and D3 receptor mRNAs in human and rat brain. Neurochem Int. 1992 Mar; 20 Suppl:33S-43S.
Mengod G, Villaró MT, Landwehrmeyer GB, Martinez-Mir MI, Niznik HB, Sunahara RK, Seeman P, O'Dowd BF, Probst A, Palacios JM. PMID: 1365451.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimals
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Transcription of a human dopamine D5 pseudogene. Biochem Biophys Res Commun. 1991 Nov 27; 181(1):16-21.
Nguyen T, Sunahara R, Marchese A, Van Tol HH, Seeman P, O'Dowd BF. PMID: 1958184.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6. Mol Pharmacol. 1991 Jul; 40(1):63-8.
Tyndale RF, Sunahara R, Inaba T, Kalow W, Gonzalez FJ, Niznik HB. PMID: 1857341.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1. Nature. 1991 Apr 18; 350(6319):614-9.
Sunahara RK, Guan HC, O'Dowd BF, Seeman P, Laurier LG, Ng G, George SR, Torchia J, Van Tol HH, Niznik HB. PMID: 1826762.
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PubMed Mentions:
202 Fields:
Translation:
HumansAnimalsCells
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Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature. 1991 Apr 18; 350(6319):610-4.
Van Tol HH, Bunzow JR, Guan HC, Sunahara RK, Seeman P, Niznik HB, Civelli O. PMID: 1840645.
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PubMed Mentions:
308 Fields:
Translation:
HumansAnimalsCells
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D1 and D2 dopamine receptor mRNA in rat brain. Proc Natl Acad Sci U S A. 1991 Mar 01; 88(5):1859-63.
Weiner DM, Levey AI, Sunahara RK, Niznik HB, O'Dowd BF, Seeman P, Brann MR. PMID: 1825729; PMCID: PMC51125.
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PubMed Mentions:
120 Fields:
Translation:
AnimalsCells
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Human dopamine D1 receptor encoded by an intronless gene on chromosome 5. Nature. 1990 Sep 06; 347(6288):80-3.
Sunahara RK, Niznik HB, Weiner DM, Stormann TM, Brann MR, Kennedy JL, Gelernter JE, Rozmahel R, Yang YL, Israel Y, et al. PMID: 1975640.
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PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
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Identification, characterization, and photoaffinity labeling of the dihydropyridine receptor associated with the L-type calcium channel from bovine adrenal medulla. Mol Pharmacol. 1990 Feb; 37(2):173-81.
Murphy BJ, Rogers CA, Sunahara RK, Lemaire S, Tuana BS. PMID: 2154669.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells