Mariko Horii

Title(s)	Assistant Adjunct Professor, Pathology
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
ORCID	0000-0002-4996-6792
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Research

Research Activities and Funding

Modeling Preeclampsia Using Human Pluripotent Stem Cells
NIH R00HD091452Jun 1, 2020 - May 31, 2023
Role: Principal Investigator

Modeling Preeclampsia Using Human Pluripotent Stem Cells
NIH K99HD091452Jun 15, 2018 - May 31, 2020
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

iPSC-based modeling of preeclampsia identifies epigenetic defects in extravillous trophoblast differentiation. iScience. 2024 Apr 19; 27(4):109569. Morey R, Bui T, Cheung VC, Dong C, Zemke JE, Requena D, Arora H, Jackson MG, Pizzo D, Theunissen TW, Horii M. PMID: 38623329; PMCID: PMC11016801.

View in: PubMed Mentions:
Discovery and verification of extracellular microRNA biomarkers for diagnostic and prognostic assessment of preeclampsia at triage. Sci Adv. 2023 Dec 22; 9(51):eadg7545. Morey R, Poling L, Srinivasan S, Martinez-King C, Anyikam A, Zhang-Rutledge K, To C, Hakim A, Mochizuki M, Verma K, Mason A, Tran V, Meads M, Lamale-Smith L, Roeder H, Horii M, Ramos GA, DeHoff P, Parast MM, Pantham P, Laurent LC. PMID: 38117879; PMCID: PMC10732528.

View in: PubMed Mentions: Fields:
Sci Science
Translation:Humans
High placental expression of FLT1, LEP, PHYHIP and IL3RA - In persons of African ancestry with severe preeclampsia. Placenta. 2023 Dec; 144:13-22. Aisagbonhi O, Bui T, Nasamran CA, St Louis H, Pizzo D, Meads M, Mulholland M, Magallanes C, Lamale-Smith L, Laurent LC, Morey R, Jacobs MB, Fisch KM, Horii M. PMID: 37949031; PMCID: PMC10843761.

View in: PubMed Mentions: Fields:
Emb Embryology Obs Obstetrics Phy Physiology
Translation:Humans
Current Strategies of Modeling Human Trophoblast Using Human Pluripotent Stem Cells in vitro. Curr Protoc. 2023 Oct; 3(10):e875. Cheung VC, Bui T, Soncin F, Bai T, Kessler JA, Parast MM, Horii M. PMID: 37787612; PMCID: PMC10558083.

View in: PubMed Mentions: Fields:
Sci Science
Translation:Humans Cells
Histopathologic and Transcriptomic Profiling Identifies Novel Trophoblast Defects in Patients With Preeclampsia and Maternal Vascular Malperfusion. Mod Pathol. 2023 02; 36(2):100035. Horii M, To C, Morey R, Jacobs MB, Li Y, Nelson KK, Meads M, Siegel BA, Pizzo D, Adami R, Zhang-Rutledge K, Lamale-Smith L, Laurent LC, Parast MM. PMID: 36853788; PMCID: PMC10081686.

View in: PubMed Mentions: 2 Fields:
Pat Pathology
Translation:Humans Cells
Modeling placental development and disease using human pluripotent stem cells. Placenta. 2023 09 26; 141:18-25. Morey R, Bui T, Fisch KM, Horii M. PMID: 36333266; PMCID: PMC10148925.

View in: PubMed Mentions: 3 Fields:
Emb Embryology Obs Obstetrics Phy Physiology
Translation:Humans Animals Cells
Derivation of functional trophoblast stem cells from primed human pluripotent stem cells. Stem Cell Reports. 2022 06 14; 17(6):1303-1317. Soncin F, Morey R, Bui T, Requena DF, Cheung VC, Kallol S, Kittle R, Jackson MG, Farah O, Chousal J, Meads M, Pizzo D, Horii M, Fisch KM, Parast MM. PMID: 35594858; PMCID: PMC9214048.

View in: PubMed Mentions: 13 Fields:
Cel Cell Biology
Translation:Humans Cells
Modeling preeclampsia using human induced pluripotent stem cells. Sci Rep. 2021 03 15; 11(1):5877. Horii M, Morey R, Bui T, Touma O, Nelson KK, Cho HY, Rishik H, Laurent LC, Parast MM. PMID: 33723311; PMCID: PMC7961010.

View in: PubMed Mentions: 23 Fields:
Sci Science
Translation:Humans Cells
High altitude regulates the expression of AMPK pathways in human placenta. Placenta. 2021 01 15; 104:267-276. Lorca RA, Houck JA, Laurent LC, Matarazzo CJ, Baker K, Horii M, Nelson KK, Bales ES, Euser AG, Parast MM, Moore LG, Julian CG. PMID: 33472134.

View in: PubMed Mentions: 6 Fields:
Emb Embryology Obs Obstetrics Phy Physiology
Translation:Humans Cells
Modeling human trophoblast, the placental epithelium at the maternal fetal interface. Reproduction. 2020 07; 160(1):R1-R11. Horii M, Touma O, Bui T, Parast MM. PMID: 32485667; PMCID: PMC7286067.

View in: PubMed Mentions: 25 Fields:
Rep Reproductive Medicine
Translation:Humans Cells
An Improved Two-Step Protocol for Trophoblast Differentiation of Human Pluripotent Stem Cells. Curr Protoc Stem Cell Biol. 2019 09; 50(1):e96. Horii M, Bui T, Touma O, Cho HY, Parast MM. PMID: 31479595; PMCID: PMC6730560.

View in: PubMed Mentions: 19 Fields:
Cel Cell Biology
Translation:Humans Cells
Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor-Dependent Manner. Am J Pathol. 2017 Apr; 187(4):767-780. Wakeland AK, Soncin F, Moretto-Zita M, Chang CW, Horii M, Pizzo D, Nelson KK, Laurent LC, Parast MM. PMID: 28167044; PMCID: PMC5397702.

View in: PubMed Mentions: 57 Fields:
Pat Pathology
Translation:Humans Cells
Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):E3882-91. Horii M, Li Y, Wakeland AK, Pizzo DP, Nelson KK, Sabatini K, Laurent LC, Liu Y, Parast MM. PMID: 27325764; PMCID: PMC4941448.

View in: PubMed Mentions: 68 Fields:
Sci Science
Translation:Humans Cells
MTA3 regulates differentiation of human cytotrophoblast stem cells. Placenta. 2015 Sep; 36(9):974-80. Horii M, Moretto-Zita M, Nelson KK, Li Y, Parast MM. PMID: 26198267; PMCID: PMC4554833.

View in: PubMed Mentions: 3 Fields:
Emb Embryology Obs Obstetrics Phy Physiology
Translation:Humans Cells
Hepatoblastoma in an infant with paternal uniparental disomy 14. Congenit Anom (Kyoto). 2012 Dec; 52(4):219-20. Horii M, Horiuchi H, Momoeda M, Nakagawa M, Hirata M, Kusakawa I, Yamanaka M. PMID: 23181499.

View in: PubMed Mentions: 4 Fields:
Ter Teratology
Translation:Humans Cells
Nitric oxide prevents phosphorylation of neuronal nitric oxide synthase at serine1412 by inhibiting the Akt/PKB and CaM-K II signaling pathways. Int J Mol Med. 2012 Jul; 30(1):15-20. Song T, Hatano N, Sugimoto K, Horii M, Yamaguchi F, Tokuda M, Miyamoto Y, Kambe T, Watanabe Y. PMID: 22576624.

View in: PubMed Mentions: 6 Fields:
Gen Genetics Mol Molecular Biology
Translation:Animals Cells
Rare sugar D-allose enhances anti-tumor effect of 5-fluorouracil on the human hepatocellular carcinoma cell line HuH-7. J Biosci Bioeng. 2008 Sep; 106(3):248-52. Yamaguchi F, Kamitori K, Sanada K, Horii M, Dong Y, Sui L, Tokuda M. PMID: 18930000.

View in: PubMed Mentions: 9 Fields:
Bio Biomedical Engineering Mic Microbiology
Translation:Humans Cells
Calcium/calmodulin-dependent protein kinase I inhibits neuronal nitric-oxide synthase activity through serine 741 phosphorylation. FEBS Lett. 2004 Jul 16; 570(1-3):133-7. Song T, Hatano N, Horii M, Tokumitsu H, Yamaguchi F, Tokuda M, Watanabe Y. PMID: 15251453.

View in: PubMed Mentions: 12 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Post-synaptic density-95 promotes calcium/calmodulin-dependent protein kinase II-mediated Ser847 phosphorylation of neuronal nitric oxide synthase. Biochem J. 2003 Jun 01; 372(Pt 2):465-71. Watanabe Y, Song T, Sugimoto K, Horii M, Araki N, Tokumitsu H, Tezuka T, Yamamoto T, Tokuda M. PMID: 12630910; PMCID: PMC1223425.

View in: PubMed Mentions: 16 Fields:
Bio Biochemistry
Translation:Animals Cells