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Francesca Soncin

Title(s)Assistant Project Scientist, Pathology
SchoolHealth Sciences
Phone858-534-8648
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    Collapse Biography 
    Collapse Education and Training
    University of Turin, Torino, ItalyBSc/MA03/2004Pharmaceutical Chemistry and Technologies
    University of Manchester, Manchester, UKMRes12/2006Life Sciences
    University of Manchester, Manchester, UKPhD12/2010Stem Cell Biology
    Collapse Awards and Honors
    European Union2002Socrates Erasmus Program
    The Armourers & Brasiers' Company2009Armourers & Brasiers’ Gauntlet Trust Award
    Marine Biological Laboratory2013Frontiers in Reproduction MBL Scholarship
    International Federation of Placenta Associations2015NIH Young Investigator Award
    International Federation of Placenta Associations 2016Elsevier Award
    Perinatal Research Society 2017PRS Young Investigator Award

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Role of VGLL1 in human placental development and trophoblast specification
    NIH R01HD096260Feb 1, 2019 - Jan 31, 2024
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Soncin F, Khater M, To C, Pizzo D, Farah O, Wakeland A, Arul Nambi Rajan K, Nelson KK, Chang CW, Moretto-Zita M, Natale DR, Laurent LC, Parast MM. Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development. Development. 2018 01 29; 145(2). PMID: 29361559.
      View in: PubMed
    2. Arul Nambi Rajan K, Khater M, Soncin F, Pizzo D, Moretto-Zita M, Pham J, Stus O, Iyer P, Tache V, Laurent LC, Parast MM. Sirtuin1 is required for proper trophoblast differentiation and placental development in mice. Placenta. 2018 02; 62:1-8. PMID: 29405961.
      View in: PubMed
    3. Wakeland AK, Soncin F, Moretto-Zita M, Chang CW, Horii M, Pizzo D, Nelson KK, Laurent LC, Parast MM. Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor-Dependent Manner. Am J Pathol. 2017 Apr; 187(4):767-780. PMID: 28167044.
      View in: PubMed
    4. Moretto Zita M, Soncin F, Natale D, Pizzo D, Parast M. Gene Expression Profiling Reveals a Novel Regulatory Role for Sox21 Protein in Mouse Trophoblast Stem Cell Differentiation. J Biol Chem. 2015 Dec 11; 290(50):30152-62. PMID: 26491013; PMCID: PMC4705987 [Available on 12/11/16].
    5. Soncin F, Natale D, Parast MM. Signaling pathways in mouse and human trophoblast differentiation: a comparative review. Cell Mol Life Sci. 2015 Apr; 72(7):1291-302. PMID: 25430479; PMCID: PMC4366325.
    6. Hawkins K, Keramari M, Soncin F, Segal JM, Mohamet L, Miazga N, Ritson S, Bobola N, Merry CL, Ward CM. Novel cell lines isolated from mouse embryonic stem cells exhibiting de novo methylation of the E-cadherin promoter. Stem Cells. 2014 Nov; 32(11):2869-79. PMID: 25074424.
      View in: PubMed
    7. Li Y, Moretto-Zita M, Soncin F, Wakeland A, Wolfe L, Leon-Garcia S, Pandian R, Pizzo D, Cui L, Nazor K, Loring JF, Crum CP, Laurent LC, Parast MM. BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ?Np63+ cytotrophoblast stem cell state. Development. 2013 Oct; 140(19):3965-76. PMID: 24004950; PMCID: PMC3775414.
    8. Losfeld ME, Soncin F, Ng BG, Singec I, Freeze HH. A sensitive green fluorescent protein biomarker of N-glycosylation site occupancy. FASEB J. 2012 Oct; 26(10):4210-7. PMID: 22691915; PMCID: PMC3448770.
    9. Soncin F, Mohamet L, Ritson S, Hawkins K, Bobola N, Zeef L, Merry CL, Ward CM. E-cadherin acts as a regulator of transcripts associated with a wide range of cellular processes in mouse embryonic stem cells. PLoS One. 2011; 6(7):e21463. PMID: 21779327; PMCID: PMC3136471.
    10. Soncin F, Ward CM. The function of e-cadherin in stem cell pluripotency and self-renewal. Genes (Basel). 2011 Feb 25; 2(1):229-59. PMID: 24710147; PMCID: PMC3924836.
    11. Oldershaw RA, Baxter MA, Lowe ET, Bates N, Grady LM, Soncin F, Brison DR, Hardingham TE, Kimber SJ. Directed differentiation of human embryonic stem cells toward chondrocytes. Nat Biotechnol. 2010 Nov; 28(11):1187-94. PMID: 20967028.
      View in: PubMed
    12. Soncin F, Mohamet L, Eckardt D, Ritson S, Eastham AM, Bobola N, Russell A, Davies S, Kemler R, Merry CL, Ward CM. Abrogation of E-cadherin-mediated cell-cell contact in mouse embryonic stem cells results in reversible LIF-independent self-renewal. Stem Cells. 2009 Sep; 27(9):2069-80. PMID: 19544408.
      View in: PubMed
    13. Eastham AM, Spencer H, Soncin F, Ritson S, Merry CL, Stern PL, Ward CM. Epithelial-mesenchymal transition events during human embryonic stem cell differentiation. Cancer Res. 2007 Dec 01; 67(23):11254-62. PMID: 18056451.
      View in: PubMed
    14. Spencer HL, Eastham AM, Merry CL, Southgate TD, Perez-Campo F, Soncin F, Ritson S, Kemler R, Stern PL, Ward CM. E-cadherin inhibits cell surface localization of the pro-migratory 5T4 oncofetal antigen in mouse embryonic stem cells. Mol Biol Cell. 2007 Aug; 18(8):2838-51. PMID: 17507657.
      View in: PubMed