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Marianna Alperin

Title(s)Associate Professor, Reproductive Medicine
SchoolHealth Sciences
Address9500 Gilman Drive #0863
La Jolla CA 92093
Phone858-534-5015
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    Collapse Biography 
    Collapse Education and Training
    St. Louis University, SOM, St. Louis, MOM.D.05/2002Medicine
    Brigham and Women's and MGH Hospitals, Harvard SOM, Boston, MA06/2005Obstetrics and Gynecology
    University of Pittsburgh, Pittsburgh, PAM.S.06/2007Research Design
    Magee Womens Hospital, University of Pittsburgh, Pittsburgh, PA06/2008Female Pelvic Medicine and Reconstructive Surgery

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Injectable Tissue-Specific Extracellular Matrix Hydrogel for Pelvic Skeletal Muscle Regeneration Following Birth Injury
    NIH/NICHD R21HD094566Dec 1, 2017 - Nov 30, 2019
    Role: Principal Investigator
    Mechanisms and impact of pregnancy-induced adaptations in pelvic floor muscles
    NIH/NICHD R01HD092515Aug 1, 2017 - Apr 30, 2022
    Role: Principal Investigator
    Impact of Aging on Structure and Function of Pelvic Floor Muscles
    NIH/NIA R03AG050951Aug 1, 2016 - Apr 30, 2018
    Role: Principal Investigator
    Architectural Design of the Pelvic Floor Skeletal Muscles
    NIH/NICHD R03HD075994Jun 25, 2013 - May 31, 2015
    Role: Principal Investigator
    UC San Diego Womens Reproductive Health Research Program
    NIH/NICHD K12HD001259Jul 23, 1999 - Nov 30, 2004
    Role: Scholar

    Collapse ORNG Applications 
    Collapse Clinical Trials
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    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Deeper dive into tissue-level events that incite and promote pelvic organ prolapse. Am J Obstet Gynecol. 2021 Jan; 224(1):1-2. Alperin M. PMID: 33386102.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Isolation of muscle stem cells from rat skeletal muscles. Stem Cell Res. 2020 03; 43:101684. Boscolo Sesillo F, Wong M, Cortez A, Alperin M. PMID: 31931473.
      View in: PubMed   Mentions:    Fields:    
    3. Age-associated changes in the mechanical properties of human cadaveric pelvic floor muscles. J Biomech. 2020 01 02; 98:109436. Burnett LA, Cook M, Shah S, Michelle Wong M, Kado DM, Alperin M. PMID: 31708240.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Uncovering changes in proteomic signature of rat pelvic floor muscles in pregnancy. Am J Obstet Gynecol. 2019 08; 221(2):130.e1-130.e9. Burnett LA, Boscolo FS, Laurent LC, Wong M, Alperin M. PMID: 31047881.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Mechanical impact of parturition-related strains on rat pelvic striated sphincters. Neurourol Urodyn. 2019 03; 38(3):912-919. Duran P, Ward S, Christman KL, Alperin M. PMID: 30779377.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    6. Multimodal imaging assessment and histologic correlation of the female rat pelvic floor muscles' anatomy. J Anat. 2019 04; 234(4):543-550. Sheth VR, Duran P, Wong J, Shah S, Du J, Christman KL, Chang EY, Alperin M. PMID: 30740685.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    7. The mysteries of menopause and urogynecologic health: clinical and scientific gaps. Menopause. 2019 01; 26(1):103-111. Alperin M, Burnett L, Lukacz E, Brubaker L. PMID: 30300297.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Recurrence of Rectal Prolapse After Surgical Repair in Women With Pelvic Organ Prolapse. Dis Colon Rectum. 2018 Jul; 61(7):861-867. Catanzarite T, Klaristenfeld DD, Tomassi MJ, Zazueta-Damian G, Alperin M. PMID: 29528907.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Pelvic muscles' mechanical response to strains in the absence and presence of pregnancy-induced adaptations in a rat model. Am J Obstet Gynecol. 2018 05; 218(5):512.e1-512.e9. Catanzarite T, Bremner S, Barlow CL, Bou-Malham L, O'Connor S, Alperin M. PMID: 29432755.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    10. The Role of the Surgeon on Outcomes of Vaginal Prolapse Surgery With Mesh. Female Pelvic Med Reconstr Surg. 2017 Sep/Oct; 23(5):293-296. Eilber KS, Alperin M, Khan A, Wu N, Pashos CL, Clemens JQ, Anger JT. PMID: 28134701.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Structure-function relationship of the human external anal sphincter. Int Urogynecol J. 2018 May; 29(5):673-678. Stewart AM, Cook MS, Dyer KY, Alperin M. PMID: 28689239.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Architectural assessment of rhesus macaque pelvic floor muscles: comparison for use as a human model. Int Urogynecol J. 2017 Oct; 28(10):1527-1535. Stewart AM, Cook MS, Esparza MC, Slayden OD, Alperin M. PMID: 28285397.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    13. Salpingo-oophorectomy at the Time of Benign Hysterectomy: A Systematic Review. Obstet Gynecol. 2016 Sep; 128(3):476-85. Evans EC, Matteson KA, Orejuela FJ, Alperin M, Balk EM, El-Nashar S, Gleason JL, Grimes C, Jeppson P, Mathews C, Wheeler TL, Murphy M. PMID: 27500347.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    14. Impact of vaginal parity and aging on the architectural design of pelvic floor muscles. Am J Obstet Gynecol. 2016 09; 215(3):312.e1-9. Alperin M, Cook M, Tuttle LJ, Esparza MC, Lieber RL. PMID: 26953079.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    15. Pregnancy-induced adaptations in intramuscular extracellular matrix of rat pelvic floor muscles. Am J Obstet Gynecol. 2016 08; 215(2):210.e1-7. Alperin M, Kaddis T, Pichika R, Esparza MC, Lieber RL. PMID: 26875952.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    16. Pregnancy-induced adaptations in the intrinsic structure of rat pelvic floor muscles. Am J Obstet Gynecol. 2015 Aug; 213(2):191.e1-7. Alperin M, Lawley DM, Esparza MC, Lieber RL. PMID: 25979618.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    17. Comparison of pelvic muscle architecture between humans and commonly used laboratory species. Int Urogynecol J. 2014 Nov; 25(11):1507-15. Alperin M, Tuttle LJ, Conner BR, Dixon DM, Mathewson MA, Ward SR, Lieber RL. PMID: 24915840.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    18. Collagen scaffold: a treatment for large mesh exposure following vaginal prolapse repair. Int Urogynecol J. 2014 Nov; 25(11):1597-9. Alperin M. PMID: 24832859.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Outcomes of vaginal prolapse surgery among female Medicare beneficiaries: the role of apical support. Obstet Gynecol. 2013 Nov; 122(5):981-7. Eilber KS, Alperin M, Khan A, Wu N, Pashos CL, Clemens JQ, Anger JT. PMID: 24104778.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    20. Architectural design of the pelvic floor is consistent with muscle functional subspecialization. Int Urogynecol J. 2014 Feb; 25(2):205-12. Tuttle LJ, Nguyen OT, Cook MS, Alperin M, Shah SB, Ward SR, Lieber RL. PMID: 23903821.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    21. Patterns of pessary care and outcomes for medicare beneficiaries with pelvic organ prolapse. Female Pelvic Med Reconstr Surg. 2013 May-Jun; 19(3):142-7. Alperin M, Khan A, Dubina E, Tarnay C, Wu N, Pashos CL, Anger JT. PMID: 23611931.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    22. A randomized trial of prophylactic uterosacral ligament suspension at the time of hysterectomy for Prevention of Vaginal Vault Prolapse (PULS): design and methods. Contemp Clin Trials. 2013 Jul; 35(2):8-12. Alperin M, Weinstein M, Kivnick S, Duong TH, Menefee S. PMID: 23587538.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Two-year outcomes after vaginal prolapse reconstruction with mesh pelvic floor repair system. Female Pelvic Med Reconstr Surg. 2013 Mar-Apr; 19(2):72-8. Alperin M, Ellison R, Meyn L, Frankman E, Zyczynski HM. PMID: 23442503.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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