Leah Bushin

Title(s)	Postdoctoral Scholar, Center for Marine Biotechnology and Biomedecine
School	Vc-marine Sciences
Address	9500 Gilman Drive # La Jolla CA 92093
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Expanding the Landscape of Noncanonical Amino Acids in RiPP Biosynthesis. J Am Chem Soc. 2024 02 14; 146(6):3805-3815. Johnson BA, Clark KA, Bushin LB, Spolar CN, Seyedsayamdost MR. PMID: 38316431.

View in: PubMed Mentions: 3 Fields:
Che Chemistry
Translation:Cells
Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs. Nat Chem Biol. 2022 10; 18(10):1135-1143. Bushin LB, Covington BC, Clark KA, Caruso A, Seyedsayamdost MR. PMID: 35953547.

View in: PubMed Mentions: 9 Fields:
Bio Biology Che Chemistry
Translation:Humans Cells
RaS-RiPPs in Streptococci and the Human Microbiome. ACS Bio Med Chem Au. 2022 Aug 17; 2(4):328-339. Clark KA, Bushin LB, Seyedsayamdost MR. PMID: 35996476; PMCID: PMC9389541.

View in: PubMed Mentions: 12
Erratum for Rued et al., "Quorum Sensing in Streptococcus mutans Regulates Production of Tryglysin, a Novel RaS-RiPP Antimicrobial Compound". mBio. 2021 Oct 26; 12(5):e0256021. Rued BE, Covington BC, Bushin LB, Szewczyk G, Laczkovich I, Seyedsayamdost MR, Federle MJ. PMID: 34607453; PMCID: PMC8546554.

View in: PubMed Mentions: 1 Fields:
Mic Microbiology
Quorum Sensing in Streptococcus mutans Regulates Production of Tryglysin, a Novel RaS-RiPP Antimicrobial Compound. mBio. 2021 03 16; 12(2). Rued BE, Covington BC, Bushin LB, Szewczyk G, Laczkovich I, Seyedsayamdost MR, Federle MJ. PMID: 33727351; PMCID: PMC8092268.

View in: PubMed Mentions: 24 Fields:
Mic Microbiology
Translation:Animals Cells
Discovery and Biosynthesis of Streptosactin, a Sactipeptide with an Alternative Topology Encoded by Commensal Bacteria in the Human Microbiome. J Am Chem Soc. 2020 09 23; 142(38):16265-16275. Bushin LB, Covington BC, Rued BE, Federle MJ, Seyedsayamdost MR. PMID: 32845143.

View in: PubMed Mentions: 27 Fields:
Che Chemistry
Translation:Humans Cells
Total Synthesis and Stereochemical Assignment of Streptide. J Am Chem Soc. 2019 10 30; 141(43):17361-17369. Isley NA, Endo Y, Wu ZC, Covington BC, Bushin LB, Seyedsayamdost MR, Boger DL. PMID: 31577142; PMCID: PMC6821584.

View in: PubMed Mentions: 10 Fields:
Che Chemistry
Translation:Cells
Macrocyclization via an Arginine-Tyrosine Crosslink Broadens the Reaction Scope of Radical S-Adenosylmethionine Enzymes. J Am Chem Soc. 2019 10 23; 141(42):16610-16614. Caruso A, Martinie RJ, Bushin LB, Seyedsayamdost MR. PMID: 31596076.

View in: PubMed Mentions: 28 Fields:
Che Chemistry
Translation:Cells
Aliphatic Ether Bond Formation Expands the Scope of Radical SAM Enzymes in Natural Product Biosynthesis. J Am Chem Soc. 2019 07 10; 141(27):10610-10615. Clark KA, Bushin LB, Seyedsayamdost MR. PMID: 31246011.

View in: PubMed Mentions: 22 Fields:
Che Chemistry
Translation:Animals Cells
A genetics-free method for high-throughput discovery of cryptic microbial metabolites. Nat Chem Biol. 2019 02; 15(2):161-168. Xu F, Wu Y, Zhang C, Davis KM, Moon K, Bushin LB, Seyedsayamdost MR. PMID: 30617293; PMCID: PMC6339573.

View in: PubMed Mentions: 61 Fields:
Bio Biology Che Chemistry
Translation:Cells
Radical Approach to Enzymatic β-Thioether Bond Formation. J Am Chem Soc. 2019 01 16; 141(2):990-997. Caruso A, Bushin LB, Clark KA, Martinie RJ, Seyedsayamdost MR. PMID: 30521328.

View in: PubMed Mentions: 29 Fields:
Che Chemistry
Translation:Cells
Charting an Unexplored Streptococcal Biosynthetic Landscape Reveals a Unique Peptide Cyclization Motif. J Am Chem Soc. 2018 12 19; 140(50):17674-17684. Bushin LB, Clark KA, Pelczer I, Seyedsayamdost MR. PMID: 30398325.

View in: PubMed Mentions: 40 Fields:
Che Chemistry
Translation:Cells
Guidelines for Determining the Structures of Radical SAM Enzyme-Catalyzed Modifications in the Biosynthesis of RiPP Natural Products. Methods Enzymol. 2018; 606:439-460. Bushin LB, Seyedsayamdost MR. PMID: 30097102.

View in: PubMed Mentions: 3 Fields:
Bio Biochemistry
Translation:Cells
Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens. J Am Chem Soc. 2017 07 12; 139(27):9203-9212. Xu F, Nazari B, Moon K, Bushin LB, Seyedsayamdost MR. PMID: 28590725; PMCID: PMC5617735.

View in: PubMed Mentions: 71 Fields:
Che Chemistry
Translation:Cells
Discovery of scmR as a global regulator of secondary metabolism and virulence in Burkholderia thailandensis E264. Proc Natl Acad Sci U S A. 2017 04 04; 114(14):E2920-E2928. Mao D, Bushin LB, Moon K, Wu Y, Seyedsayamdost MR. PMID: 28320949; PMCID: PMC5389298.

View in: PubMed Mentions: 42 Fields:
Sci Science
Translation:Animals Cells
Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae. ACS Chem Biol. 2017 03 17; 12(3):814-824. Metelev M, Arseniev A, Bushin LB, Kuznedelov K, Artamonova TO, Kondratenko R, Khodorkovskii M, Seyedsayamdost MR, Severinov K. PMID: 28106375.

View in: PubMed Mentions: 26 Fields:
Bio Biochemistry Bio Biology
Translation:Humans Cells
Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis. ACS Chem Biol. 2016 08 19; 11(8):2124-30. Okada BK, Wu Y, Mao D, Bushin LB, Seyedsayamdost MR. PMID: 27367535; PMCID: PMC6786267.

View in: PubMed Mentions: 37 Fields:
Bio Biochemistry Bio Biology
Translation:Cells
Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink. Nat Chem. 2015 May; 7(5):431-437. Schramma KR, Bushin LB, Seyedsayamdost MR. PMID: 25901822; PMCID: PMC4443489.

View in: PubMed Mentions: 92 Fields:
Che Chemistry
Translation:Cells