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    Stanley Opella

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentChemistry and Biochemistry
    Address9500 Gilman Drive #0307
    CA La Jolla 92093
    Phone858-822-4820
    vCardDownload vCard

      Collapse Research 
      Collapse Research Activities and Funding
      Structures, Dynamics, and Functions of Membrane Proteins
      NIH/NIGMS R35GM122501May 1, 2017 - Apr 30, 2022
      Role: Principal Investigator
      Structure Determination of Membrane Proteins in Phospholipid Bilyaers
      NIH/NIGMS R01GM099986Apr 1, 2012 - Mar 31, 2016
      Role: Principal Investigator
      Protein-Protein Interaction in Natural Product Biosynthesis
      NIH/NIGMS R01GM095970Mar 1, 2012 - Jan 31, 2020
      Role: Principal Investigator
      Acquisition of a Cryoprobe for an 800 MHz NMR Spectrometer
      NIH/NCRR S10RR023773Mar 1, 2008 - Feb 28, 2009
      Role: Principal Investigator
      Membrane Protein Structures in Phospholipid Bilayers by Solid State NMR
      NIH/NIGMS R01GM075877Sep 23, 2005 - Jul 31, 2011
      Role: Principal Investigator
      Molecular Imaging of G-Protein-Coupled Receptors for Drug Development
      NIH/NIBIB R01EB005161Apr 1, 2005 - Apr 30, 2015
      Role: Principal Investigator
      Structure, Dynamics, and Functions of the Viroporins Vpu from HIV and p7 from HCV
      NIH/NIGMS R01GM066978Jul 1, 2003 - Jul 31, 2017
      Role: Principal Investigator
      CONFERENCE ON FRONTIERS OF NMR IN MOLECULAR BIOLOGY VII
      NIH/NCI R13CA088925Mar 5, 2001 - Feb 28, 2002
      Role: Principal Investigator
      PHAGE DISPLAY--STRUCTURE, BIOLOGY AND APPLICATIONS
      NIH/NCI R13CA090984Sep 1, 2000 - Dec 31, 2003
      Role: Principal Investigator
      CONFERENCE ON FRONTIERS OF NMR IN MOLECULAR BIOLOGY
      NIH/NIDDK R13DK054982Jan 1, 1999 - Dec 31, 1999
      Role: Principal Investigator
      NMR PROBES FOR MEMBRANE PROTEIN STRUCTURE DETERMINATION
      NIH/NCRR R01RR012599Aug 1, 1998 - Mar 31, 2003
      Role: Principal Investigator
      STRUCTURAL BIOLOGY OF AIDS RELATED PROJECTS
      NIH/NIGMS P01GM056538Aug 1, 1997 - Nov 30, 2003
      Role: Principal Investigator
      Resource for NMR Molecular Imaging of Proteins
      NIH/NIBIB P41EB002031Apr 10, 1994 - May 31, 2019
      Role: Principal Investigator
      RESOURCE FOR SOLID STATE NMR OF PROTEINS
      NIH/NCRR P41RR009793Apr 10, 1994 - May 30, 2004
      Role: Principal Investigator
      PROTEIN STRUCTURE BY SOLID-STATE NMR SPECTROSCOPY
      NIH/NCRR R24RR005976Apr 1, 1991 - Mar 31, 1994
      Role: Principal Investigator
      NMR STRUCTURAL STUDIES OF MEMBRANE PROTEINS
      NIH/NIAID R01AI020770Dec 1, 1984 - Jun 30, 1998
      Role: Principal Investigator
      SOLID STATE NMR OF PEPTIDES
      NIH/NIBIB R01EB002169Jan 1, 1982 - Mar 31, 2006
      Role: Principal Investigator
      SOLID STATE NMR OF PEPTIDES
      NIH/NIGMS R01GM029754Jan 1, 1982 - Mar 31, 2005
      Role: Principal Investigator
      Consolidated Basic Cancer Research Program
      NIH P30CA010815Sep 1, 1978 - Feb 28, 2019
      Role: Co-Investigator
      NMR Studies of Biological Supramolecular Structures
      NIH/NIBIB R01EB001966Aug 1, 1977 - Feb 28, 2009
      Role: Principal Investigator
      NMR STUDIES OF BIOLOGICAL SUPRAMOLECULAR STRUCTURES
      NIH/NIGMS R37GM024266Aug 1, 1977 - Mar 31, 2004
      Role: Principal Investigator
      NMR STUDIES OF BIOLOGICAL SUPRAMOLECULAR STRUCTURES
      NIH/NIGMS R01GM024266Aug 1, 1977 - Jul 31, 1993
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Amin A, Latif Z, Opella S. Expression and Purification of Transmembrane Protein MerE from Mercury Resistant Bacillus cereus. J Microbiol Biotechnol. 2017 Aug 08. PMID: 28783894.
        View in: PubMed
      2. Opella S, Marassi FM. Applications of NMR to membrane proteins. Arch Biochem Biophys. 2017 Aug 15; 628:92-101. PMID: 28529197.
        View in: PubMed
      3. Yao Y, Dutta SK, Park SH, Rai R, Fujimoto LM, Bobkov AA, Opella S, Marassi FM. High resolution solid-state NMR spectroscopy of the Yersinia pestis outer membrane protein Ail in lipid membranes. J Biomol NMR. 2017 Mar; 67(3):179-190. PMID: 28239773.
        View in: PubMed
      4. Tian Y, Schwieters CD, Opella S, Marassi FM. High quality NMR structures: a new force field with implicit water and membrane solvation for Xplor-NIH. J Biomol NMR. 2016 Dec 29. PMID: 28035651.
        View in: PubMed
      5. Das BB, Opella S. Simultaneous cross polarization to (13)C and (15)N with (1)H detection at 60kHz MAS solid-state NMR. J Magn Reson. 2016 Jan; 262:20-6. PMID: 26705905.
        View in: PubMed
      6. Zhang H, Lin EC, Das BB, Tian Y, Opella S. Structural determination of virus protein U from HIV-1 by NMR in membrane environments. Biochim Biophys Acta. 2015 Nov; 1848(11 Pt A):3007-18. PMID: 26362058.
        View in: PubMed
      7. Jaremko MJ, Lee DJ, Opella S, Burkart MD. Structure and Substrate Sequestration in the Pyoluteorin Type II Peptidyl Carrier Protein PltL. J Am Chem Soc. 2015 Sep 16; 137(36):11546-9. PMID: 26340431.
        View in: PubMed
      8. Tian Y, Schwieters CD, Opella S, Marassi FM. A Practical Implicit Membrane Potential for NMR Structure Calculations of Membrane Proteins. Biophys J. 2015 Aug 4; 109(3):574-85. PMID: 26244739.
        View in: PubMed
      9. Opella S. Relating structure and function of viral membrane-spanning miniproteins. Curr Opin Virol. 2015 Jun; 12:121-5. PMID: 26057606.
        View in: PubMed
      10. Lewinski MK, Jafari M, Zhang H, Opella S, Guatelli J. Membrane Anchoring by a C-terminal Tryptophan Enables HIV-1 Vpu to Displace Bone Marrow Stromal Antigen 2 (BST2) from Sites of Viral Assembly. J Biol Chem. 2015 Apr 24; 290(17):10919-33. PMID: 25759385.
        View in: PubMed
      11. Opella S. Solid-state NMR and membrane proteins. J Magn Reson. 2015 Apr; 253:129-37. PMID: 25681966.
        View in: PubMed
      12. Park SH, Wang VS, Radoicic J, De Angelis AA, Berkamp S, Opella S. Paramagnetic relaxation enhancement of membrane proteins by incorporation of the metal-chelating unnatural amino acid 2-amino-3-(8-hydroxyquinolin-3-yl)propanoic acid (HQA). J Biomol NMR. 2015 Apr; 61(3-4):185-96. PMID: 25430059.
        View in: PubMed
      13. Tian Y, Lu GJ, Marassi FM, Opella S. Structure of the membrane protein MerF, a bacterial mercury transporter, improved by the inclusion of chemical shift anisotropy constraints. J Biomol NMR. 2014 Sep; 60(1):67-71. PMID: 25103921.
        View in: PubMed
      14. Radoicic J, Lu GJ, Opella S. NMR structures of membrane proteins in phospholipid bilayers. Q Rev Biophys. 2014 Aug; 47(3):249-83. PMID: 25032938.
        View in: PubMed
      15. Wu CH, De Angelis AA, Opella S. Magic angle Lee-Goldburg frequency offset irradiation improves the efficiency and selectivity of SPECIFIC-CP in triple-resonance MAS solid-state NMR. J Magn Reson. 2014 Sep; 246:1-3. PMID: 25051542.
        View in: PubMed
      16. Das BB, Opella S. Multiple acquisition/multiple observation separated local field/chemical shift correlation solid-state magic angle spinning NMR spectroscopy. J Magn Reson. 2014 Aug; 245:98-104. PMID: 25023566.
        View in: PubMed
      17. Das BB, Park SH, Opella S. Membrane protein structure from rotational diffusion. Biochim Biophys Acta. 2015 Jan; 1848(1 Pt B):229-45. PMID: 24747039.
        View in: PubMed
      18. Tian Y, Schwieters CD, Opella S, Marassi FM. A practical implicit solvent potential for NMR structure calculation. J Magn Reson. 2014 Jun; 243:54-64. PMID: 24747742.
        View in: PubMed
      19. Lu GJ, Opella S. Mechanism of dilute-spin-exchange in solid-state NMR. J Chem Phys. 2014 Mar 28; 140(12):124201. PMID: 24697432.
        View in: PubMed
      20. Das BB, Zhang H, Opella S. Dipolar Assisted Assignment Protocol (DAAP) for MAS solid-state NMR of rotationally aligned membrane proteins in phospholipid bilayers. J Magn Reson. 2014 May; 242:224-32. PMID: 24698983.
        View in: PubMed
      21. Perrin BS, Tian Y, Fu R, Grant CV, Chekmenev EY, Wieczorek WE, Dao AE, Hayden RM, Burzynski CM, Venable RM, Sharma M, Opella S, Pastor RW, Cotten ML. High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion. J Am Chem Soc. 2014 Mar 5; 136(9):3491-504. PMID: 24410116.
        View in: PubMed
      22. Opella S. The development of solid-state NMR of membrane proteins. Biomed Spectrosc Imaging. 2014; 3(2):81-105. PMID: 26069880.
        View in: PubMed
      23. Nguyen C, Haushalter RW, Lee DJ, Markwick PR, Bruegger J, Caldara-Festin G, Finzel K, Jackson DR, Ishikawa F, O'Dowd B, McCammon JA, Opella S, Tsai SC, Burkart MD. Trapping the dynamic acyl carrier protein in fatty acid biosynthesis. Nature. 2014 Jan 16; 505(7483):427-31. PMID: 24362570.
        View in: PubMed
      24. Lu GJ, Opella S. Resonance assignments of a membrane protein in phospholipid bilayers by combining multiple strategies of oriented sample solid-state NMR. J Biomol NMR. 2014 Jan; 58(1):69-81. PMID: 24356892.
        View in: PubMed
      25. Lin EC, Opella S. Covariance spectroscopy in high-resolution multi-dimensional solid-state NMR. J Magn Reson. 2014 Feb; 239:57-60. PMID: 24380813.
        View in: PubMed
      26. Gleason NJ, Greathouse DV, Grant CV, Opella S, Koeppe RE. Single Tryptophan and Tyrosine Comparisons in the N-Terminal and C-Terminal Interface Regions of Transmembrane GWALP Peptides. J Phys Chem B. 2013 Nov 7; 117(44):13786-94. PMID: 24111589.
        View in: PubMed
      27. Park SH, Yang C, Opella S, Mueller LJ. Resolution and measurement of heteronuclear dipolar couplings of a noncrystalline protein immobilized in a biological supramolecular assembly by proton-detected MAS solid-state NMR spectroscopy. J Magn Reson. 2013 Dec; 237:164-8. PMID: 24225529.
        View in: PubMed
      28. Wang Y, Park SH, Tian Y, Opella S. Impact of histidine residues on the transmembrane helices of viroporins. Mol Membr Biol. 2013 Nov; 30(7):360-9. PMID: 24102567.
        View in: PubMed
      29. Das BB, Lin EC, Opella S. Experiments optimized for magic angle spinning and oriented sample solid-state NMR of proteins. J Phys Chem B. 2013 Oct 17; 117(41):12422-31. PMID: 24044695.
        View in: PubMed
      30. Lin EC, Opella S. Sampling scheme and compressed sensing applied to solid-state NMR spectroscopy. J Magn Reson. 2013 Dec; 237:40-8. PMID: 24140622.
        View in: PubMed
      31. Lu GJ, Opella S. Motion-adapted pulse sequences for oriented sample (OS) solid-state NMR of biopolymers. J Chem Phys. 2013 Aug 28; 139(8):084203. PMID: 24006989.
        View in: PubMed
      32. Cook GA, Dawson LA, Tian Y, Opella S. Three-Dimensional Structure and Interaction Studies of Hepatitis C Virus p7 in 1,2-Dihexanoyl-sn-glycero-3-phosphocholine by Solution Nuclear Magnetic Resonance. Biochemistry. 2013 Aug 6; 52(31):5295-303. PMID: 23841474.
        View in: PubMed
      33. Opella S. Structure determination of membrane proteins in their native phospholipid bilayer environment by rotationally aligned solid-state NMR spectroscopy. Acc Chem Res. 2013 Sep 17; 46(9):2145-53. PMID: 23829871.
        View in: PubMed
      34. Lu GJ, Tian Y, Vora N, Marassi FM, Opella S. The structure of the mercury transporter MerF in phospholipid bilayers: a large conformational rearrangement results from N-terminal truncation. J Am Chem Soc. 2013 Jun 26; 135(25):9299-302. PMID: 23763519.
        View in: PubMed
      35. Opella S. Structure determination of membrane proteins by nuclear magnetic resonance spectroscopy. Annu Rev Anal Chem (Palo Alto Calif). 2013; 6:305-28. PMID: 23577669.
        View in: PubMed
      36. Yao Y, Ding Y, Tian Y, Opella S, Marassi FM. Membrane protein structure determination: back to the membrane. Methods Mol Biol. 2013; 1063:145-58. PMID: 23975776.
        View in: PubMed
      37. Rankenberg JM, Vostrikov VV, Greathouse DV, Grant CV, Opella S, Koeppe RE. Properties of membrane-incorporated WALP peptides that are anchored on only one end. Biochemistry. 2012 Dec 18; 51(50):10066-74. PMID: 23171005.
        View in: PubMed
      38. Park SH, Das BB, Casagrande F, Tian Y, Nothnagel HJ, Chu M, Kiefer H, Maier K, De Angelis AA, Marassi FM, Opella S. Structure of the chemokine receptor CXCR1 in phospholipid bilayers. Nature. 2012 Nov 29; 491(7426):779-83. PMID: 23086146.
        View in: PubMed
      39. Tian Y, Opella S, Marassi FM. Improved chemical shift prediction by Rosetta conformational sampling. J Biomol NMR. 2012 Nov; 54(3):237-43. PMID: 23007199.
        View in: PubMed
      40. Lu GJ, Park SH, Opella S. Improved 1H amide resonance line narrowing in oriented sample solid-state NMR of membrane proteins in phospholipid bilayers. J Magn Reson. 2012 Jul; 220:54-61. PMID: 22683581.
        View in: PubMed
      41. Rankenberg JM, Vostrikov VV, DuVall CD, Greathouse DV, Koeppe RE, Grant CV, Opella S. Proline kink angle distributions for GWALP23 in lipid bilayers of different thicknesses. Biochemistry. 2012 May 1; 51(17):3554-64. PMID: 22489564.
        View in: PubMed
      42. Gleason NJ, Vostrikov VV, Greathouse DV, Grant CV, Opella S, Koeppe RE. Tyrosine replacing tryptophan as an anchor in GWALP peptides. Biochemistry. 2012 Mar 13; 51(10):2044-53. PMID: 22364236.
        View in: PubMed
      43. Das BB, Nothnagel HJ, Lu GJ, Son WS, Tian Y, Marassi FM, Opella S. Structure determination of a membrane protein in proteoliposomes. J Am Chem Soc. 2012 Feb 1; 134(4):2047-56. PMID: 22217388.
        View in: PubMed
      44. Vostrikov VV, Grant CV, Opella S, Koeppe RE. On the combined analysis of ²H and ¹5N/¹H solid-state NMR data for determination of transmembrane peptide orientation and dynamics. Biophys J. 2011 Dec 21; 101(12):2939-47. PMID: 22208192.
        View in: PubMed
      45. Skasko M, Wang Y, Tian Y, Tokarev A, Munguia J, Ruiz A, Stephens EB, Opella S, Guatelli J. HIV-1 Vpu protein antagonizes innate restriction factor BST-2 via lipid-embedded helix-helix interactions. J Biol Chem. 2012 Jan 2; 287(1):58-67. PMID: 22072710.
        View in: PubMed
      46. Son WS, Park SH, Nothnagel HJ, Lu GJ, Wang Y, Zhang H, Cook GA, Howell SC, Opella S. 'q-Titration' of long-chain and short-chain lipids differentiates between structured and mobile residues of membrane proteins studied in bicelles by solution NMR spectroscopy. J Magn Reson. 2012 Jan; 214(1):111-8. PMID: 22079194.
        View in: PubMed
      47. Park SH, Casagrande F, Chu M, Maier K, Kiefer H, Opella S. Optimization of purification and refolding of the human chemokine receptor CXCR1 improves the stability of proteoliposomes for structure determination. Biochim Biophys Acta. 2012 Mar; 1818(3):584-91. PMID: 22024025.
        View in: PubMed
      48. Park SH, Casagrande F, Cho L, Albrecht L, Opella S. Interactions of interleukin-8 with the human chemokine receptor CXCR1 in phospholipid bilayers by NMR spectroscopy. J Mol Biol. 2011 Nov 25; 414(2):194-203. PMID: 22019593.
        View in: PubMed
      49. Tian Y, Schwieters CD, Opella S, Marassi FM. AssignFit: a program for simultaneous assignment and structure refinement from solid-state NMR spectra. J Magn Reson. 2012 Jan; 214(1):42-50. PMID: 22036904.
        View in: PubMed
      50. Park SH, Berkamp S, Cook GA, Chan MK, Viadiu H, Opella S. Nanodiscs versus macrodiscs for NMR of membrane proteins. Biochemistry. 2011 Oct 25; 50(42):8983-5. PMID: 21936505.
        View in: PubMed
      51. Marassi FM, Das BB, Lu GJ, Nothnagel HJ, Park SH, Son WS, Tian Y, Opella S. Structure determination of membrane proteins in five easy pieces. Methods. 2011 Dec; 55(4):363-9. PMID: 21964394.
        View in: PubMed
      52. De Angelis AA, Grant CV, Baxter MK, McGavin JA, Opella S, Cotten ML. Amphipathic antimicrobial piscidin in magnetically aligned lipid bilayers. Biophys J. 2011 Sep 7; 101(5):1086-94. PMID: 21889445.
        View in: PubMed
      53. Lin EC, Opella S. 1H assisted 13C/15N heteronuclear correlation spectroscopy in oriented sample solid-state NMR of single crystal and magnetically aligned samples. J Magn Reson. 2011 Jul; 211(1):37-44. PMID: 21543244.
        View in: PubMed
      54. Park SH, Casagrande F, Das BB, Albrecht L, Chu M, Opella S. Local and global dynamics of the G protein-coupled receptor CXCR1. Biochemistry. 2011 Mar 29; 50(12):2371-80. PMID: 21323370.
        View in: PubMed
      55. Haushalter RW, Filipp FV, Ko KS, Yu R, Opella S, Burkart MD. Binding and "pKa" modulation of a polycyclic substrate analogue in a type II polyketide acyl carrier protein. ACS Chem Biol. 2011 May 20; 6(5):413-8. PMID: 21268653.
        View in: PubMed
      56. Lu GJ, Son WS, Opella S. A general assignment method for oriented sample (OS) solid-state NMR of proteins based on the correlation of resonances through heteronuclear dipolar couplings in samples aligned parallel and perpendicular to the magnetic field. J Magn Reson. 2011 Apr; 209(2):195-206. PMID: 21316275.
        View in: PubMed
      57. Cook GA, Stefer S, Opella S. Expression and purification of the membrane protein p7 from hepatitis C virus. Biopolymers. 2011; 96(1):32-40. PMID: 20560141.
        View in: PubMed
      58. Park SH, Das BB, De Angelis AA, Scrima M, Opella S. Mechanically, magnetically, and "rotationally aligned" membrane proteins in phospholipid bilayers give equivalent angular constraints for NMR structure determination. J Phys Chem B. 2010 Nov 11; 114(44):13995-4003. PMID: 20961141.
        View in: PubMed
      59. Park SH, Opella S. Triton X-100 as the "short-chain lipid" improves the magnetic alignment and stability of membrane proteins in phosphatidylcholine bilayers for oriented-sample solid-state NMR spectroscopy. J Am Chem Soc. 2010 Sep 15; 132(36):12552-3. PMID: 20735058.
        View in: PubMed
      60. Park SH, Marassi FM, Black D, Opella S. Structure and dynamics of the membrane-bound form of Pf1 coat protein: implications of structural rearrangement for virus assembly. Biophys J. 2010 Sep 8; 99(5):1465-74. PMID: 20816058.
        View in: PubMed
      61. Opella S. Perspectives in magnetic resonance. J Magn Reson. 2010 Sep; 206(1):1. PMID: 20727502.
        View in: PubMed
      62. Cook GA, Zhang H, Park SH, Wang Y, Opella S. Comparative NMR studies demonstrate profound differences between two viroporins: p7 of HCV and Vpu of HIV-1. Biochim Biophys Acta. 2011 Feb; 1808(2):554-60. PMID: 20727848.
        View in: PubMed
      63. Cook GA, Opella S. Secondary structure, dynamics, and architecture of the p7 membrane protein from hepatitis C virus by NMR spectroscopy. Biochim Biophys Acta. 2011 Jun; 1808(6):1448-53. PMID: 20727850.
        View in: PubMed
      64. Shealy P, Simin M, Park SH, Opella S, Valafar H. Simultaneous structure and dynamics of a membrane protein using REDCRAFT: membrane-bound form of Pf1 coat protein. J Magn Reson. 2010 Nov; 207(1):8-16. PMID: 20829084.
        View in: PubMed
      65. Lin EC, Wu CH, Yang Y, Grant CV, Opella S. 1H-13C separated local field spectroscopy of uniformly 13C labeled peptides and proteins. J Magn Reson. 2010 Sep; 206(1):105-11. PMID: 20637662.
        View in: PubMed
      66. Knox RW, Lu GJ, Opella S, Nevzorov AA. A resonance assignment method for oriented-sample solid-state NMR of proteins. J Am Chem Soc. 2010 Jun 23; 132(24):8255-7. PMID: 20509649.
        View in: PubMed
      67. Grant CV, Wu CH, Opella S. Probes for high field solid-state NMR of lossy biological samples. J Magn Reson. 2010 Jun; 204(2):180-8. PMID: 20435493.
        View in: PubMed
      68. Cook GA, Opella S. NMR studies of membrane proteins. Methods Mol Biol. 2010; 637:263-75. PMID: 20419440.
        View in: PubMed
      69. Wu CH, Das BB, Opella S. (1)H-(13)C Hetero-nuclear dipole-dipole couplings of methyl groups in stationary and magic angle spinning solid-state NMR experiments of peptides and proteins. J Magn Reson. 2010 Feb; 202(2):127-34. PMID: 19896874.
        View in: PubMed
      70. Park SH, Son WS, Mukhopadhyay R, Valafar H, Opella S. Phage-induced alignment of membrane proteins enables the measurement and structural analysis of residual dipolar couplings with dipolar waves and lambda-maps. J Am Chem Soc. 2009 Oct 14; 131(40):14140-1. PMID: 19761238.
        View in: PubMed
      71. Cook GA, Opella S. NMR studies of p7 protein from hepatitis C virus. Eur Biophys J. 2010 Jun; 39(7):1097-104. PMID: 19727701.
        View in: PubMed
      72. Filipp FV, Sinha N, Jairam L, Bradley J, Opella S. Labeling strategies for 13C-detected aligned-sample solid-state NMR of proteins. J Magn Reson. 2009 Dec; 201(2):121-30. PMID: 19781966.
        View in: PubMed
      73. Grant CV, Yang Y, Glibowicka M, Wu CH, Park SH, Deber CM, Opella S. A Modified Alderman-Grant Coil makes possible an efficient cross-coil probe for high field solid-state NMR of lossy biological samples. J Magn Reson. 2009 Nov; 201(1):87-92. PMID: 19733108.
        View in: PubMed
      74. Wu CH, Grant CV, Cook GA, Park SH, Opella S. A strip-shield improves the efficiency of a solenoid coil in probes for high-field solid-state NMR of lossy biological samples. J Magn Reson. 2009 Sep; 200(1):74-80. PMID: 19559634.
        View in: PubMed
      75. Opella S. Faster is better: improving the sensitivity of solid-state NMR. Nat Methods. 2009 Mar; 6(3):197-8. PMID: 19247292.
        View in: PubMed
      76. Diller A, Loudet C, Aussenac F, Raffard G, Fournier S, Laguerre M, Grélard A, Opella S, Marassi FM, Dufourc EJ. Bicelles: A natural 'molecular goniometer' for structural, dynamical and topological studies of molecules in membranes. Biochimie. 2009 Jun; 91(6):744-51. PMID: 19248817.
        View in: PubMed
      77. Page RC, Lee S, Moore JD, Opella S, Cross TA. Backbone structure of a small helical integral membrane protein: A unique structural characterization. Protein Sci. 2009 Jan; 18(1):134-46. PMID: 19177358.
        View in: PubMed
      78. Vostrikov VV, Grant CV, Daily AE, Opella S, Koeppe RE. Comparison of "Polarization inversion with spin exchange at magic angle" and "geometric analysis of labeled alanines" methods for transmembrane helix alignment. J Am Chem Soc. 2008 Sep 24; 130(38):12584-5. PMID: 18763771.
        View in: PubMed
      79. Park SH, Loudet C, Marassi FM, Dufourc EJ, Opella S. Solid-state NMR spectroscopy of a membrane protein in biphenyl phospholipid bicelles with the bilayer normal parallel to the magnetic field. J Magn Reson. 2008 Jul; 193(1):133-8. PMID: 18492613.
        View in: PubMed
      80. Wu CH, Opella S. Shiftless nuclear magnetic resonance spectroscopy. J Chem Phys. 2008 Feb 7; 128(5):052312. PMID: 18266429.
        View in: PubMed
      81. Opella S, Zeri AC, Park SH. Structure, dynamics, and assembly of filamentous bacteriophages by nuclear magnetic resonance spectroscopy. Annu Rev Phys Chem. 2008; 59:635-57. PMID: 18393681.
        View in: PubMed
      82. Sinha N, Filipp FV, Jairam L, Park SH, Bradley J, Opella S. Tailoring 13C labeling for triple-resonance solid-state NMR experiments on aligned samples of proteins. Magn Reson Chem. 2007 Dec; 45 Suppl 1:S107-15. PMID: 18157808.
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      83. Wu CH, Opella S. Proton-detected separated local field spectroscopy. J Magn Reson. 2008 Jan; 190(1):165-70. PMID: 17981481.
        View in: PubMed
      84. Müller SD, De Angelis AA, Walther TH, Grage SL, Lange C, Opella S, Ulrich AS. Structural characterization of the pore forming protein TatAd of the twin-arginine translocase in membranes by solid-state 15N-NMR. Biochim Biophys Acta. 2007 Dec; 1768(12):3071-9. PMID: 17980349.
        View in: PubMed
      85. Lee S, Howell SB, Opella S. NMR and mutagenesis of human copper transporter 1 (hCtr1) show that Cys-189 is required for correct folding and dimerization. Biochim Biophys Acta. 2007 Dec; 1768(12):3127-34. PMID: 17959139.
        View in: PubMed
      86. Park SH, Opella S. Conformational changes induced by a single amino acid substitution in the trans-membrane domain of Vpu: implications for HIV-1 susceptibility to channel blocking drugs. Protein Sci. 2007 Oct; 16(10):2205-15. PMID: 17766368.
        View in: PubMed
      87. Grant CV, Sit SL, De Angelis AA, Khuong KS, Wu CH, Plesniak LA, Opella S. An efficient (1)H/(31)P double-resonance solid-state NMR probe that utilizes a scroll coil. J Magn Reson. 2007 Oct; 188(2):279-84. PMID: 17719813.
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      88. Kim MJ, Park SH, Opella S, Marsilje TH, Michellys PY, Seidel HM, Tian SS. NMR structural studies of interactions of a small, nonpeptidyl Tpo mimic with the thrombopoietin receptor extracellular juxtamembrane and transmembrane domains. J Biol Chem. 2007 May 11; 282(19):14253-61. PMID: 17369254.
        View in: PubMed
      89. Sinha N, Grant CV, Park SH, Brown JM, Opella S. Triple resonance experiments for aligned sample solid-state NMR of (13)C and (15)N labeled proteins. J Magn Reson. 2007 May; 186(1):51-64. PMID: 17293139.
        View in: PubMed
      90. Das BB, Ajithkumar TG, Sinha N, Opella S, Ramanathan KV. Cross- and axial-peak intensities in 2D-SLF experiments based on cross-polarization--the role of the initial density matrix. J Magn Reson. 2007 Apr; 185(2):308-17. PMID: 17280846.
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      91. Nevzorov AA, Park SH, Opella S. Three-dimensional experiment for solid-state NMR of aligned protein samples in high field magnets. J Biomol NMR. 2007 Feb; 37(2):113-6. PMID: 17216304.
        View in: PubMed
      92. De Angelis AA, Opella S. Bicelle samples for solid-state NMR of membrane proteins. Nat Protoc. 2007; 2(10):2332-8. PMID: 17947974.
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      206. Gall CM, Cross TA, DiVerdi JA, Opella S. Protein dynamics by solid-state NMR: aromatic rings of the coat protein in fd bacteriophage. Proc Natl Acad Sci U S A. 1982 Jan; 79(1):101-5. PMID: 6948294.
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      207. Fritzsche H, Cross TA, Opella S, Kallenbach NR. Structure and architecture of the bacterial virus fd. An infrared linear dichroism study. Biophys Chem. 1981 Nov; 14(3):283-91. PMID: 7326351.
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      208. DiVerdi JA, Opella S, Ma RI, Kallenbach NR, Seeman NC. 31P NMR of DNA in eukaryotic chromosomal complexes. Biochem Biophys Res Commun. 1981 Oct 15; 102(3):885-90. PMID: 7306194.
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      209. DiVerdi JA, Opella S. Dynamics of B-DNA in the solid state. J Mol Biol. 1981 Jun 25; 149(2):307-11. PMID: 7310883.
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      210. Opella S, Wise WB, DiVerdi JA. Deoxyribonucleic acid dynamics from phosphorus-31 nuclear magnetic resonance. Biochemistry. 1981 Jan 20; 20(2):284-90. PMID: 7193483.
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      211. DiVerdi JA, Opella S. Phosphorus-31 nuclear magnetic resonance of fd virus. Biochemistry. 1981 Jan 20; 20(2):280-4. PMID: 7008839.
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      212. Cross TA, Opella S. Hydrogen-1 and carbon-13 nuclear magnetic resonance of the aromatic residues of fd coat protein. Biochemistry. 1981 Jan 20; 20(2):290-7. PMID: 7008840.
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      213. Cross TA, Gall CM, Opella S. NMR studies of filamentous bacteriophage assembly. Prog Clin Biol Res. 1981; 64:457-65. PMID: 7330059.
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      214. Opella S, Cross TA, DiVerdi JA, Sturm CF. Nuclear magnetic resonance of the filamentous bacteriophage fd. Biophys J. 1980 Oct; 32(1):531-48. PMID: 7018608.
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      215. Cross TA, Opella S. Structural properties of fd coat protein in sodium dodecyl sulfate micelles. Biochem Biophys Res Commun. 1980 Jan 29; 92(2):478-84. PMID: 6986868.
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      216. Cross TA, Opella S. NMR of fd coat protein. J Supramol Struct. 1979; 11(2):139-45. PMID: 44890.
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      217. Moo-Penn WF, Bechtel KC, Schmidt RM, Johnson MH, Jue DL, Schmidt DE, Dunlap WM, Opella S, Bonaventura J, Bonaventura C. Hemoglobin Raleigh (beta1 valine replaced by acetylalanine). Structural and functional characterization. Biochemistry. 1977 Nov 1; 16(22):4872-9. PMID: 20942.
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      218. Opella S. Biological nuclear magnetic resonance spectroscopy. Science. 1977 Oct 14; 198(4313):158-65. PMID: 20662.
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      219. Matthews HR, Matthews KS, Opella S. Selectively deuterated amino acid analogues. Synthesis, incorporation into proteins and NMR properties. Biochim Biophys Acta. 1977 Mar 29; 497(1):1-13. PMID: 321035.
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      220. Nelson DJ, Opella S, Jardetzky O. 13C nuclear magnetic resonance study of molecular motions and conformational transitions in muscle calcium binding parvalbumins. Biochemistry. 1976 Dec 14; 15(25):5552-60. PMID: 999828.
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      221. Opella S, Yesinowski JP, Waugh JS. Nuclear magnetic resonance description of molecular motion and phase separations of cholesterol in lecithin dispersions. Proc Natl Acad Sci U S A. 1976 Nov; 73(11):3812-5. PMID: 1069266.
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      222. Roberts MF, Opella S, Schaffer MH, Phillips HM, Stark GR. Evidence from 13C NMR for protonation of carbamyl-P and N-(phosphonacetyl)-L-aspartate in the active site of aspartate transcarbamylase. J Biol Chem. 1976 Oct 10; 251(19):5976-85. PMID: 9410.
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      223. Cozzone PJ, Opella S, Jardetzky O, Berthou J, Jollès P. Detection of new temperature-dependent conformational transition in lysozyme by carbon-13 nuclear magnetic resonance spectroscopy. Proc Natl Acad Sci U S A. 1975 Jun; 72(6):2095-8. PMID: 1056017.
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      224. Bauer DR, Opella S, Nelson DJ, Pecora R. Letter: Depolarized light scattering and carbon nuclear resonance measurements of the isotropic rotational correlation time of muscle calcium binding protein. J Am Chem Soc. 1975 Apr 30; 97(9):2580-2. PMID: 1133427.
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      225. Opella S, Nelson DJ, Jardetzyk O. Letter: Carbon magnetic resonance study of the conformational changes in carp muscle calcium binding parvalbumin. J Am Chem Soc. 1974 Oct 30; 96(22):7157-9. PMID: 4474190.
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